K-33 Endocrine System, Fk Usu,Rev

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    Dr. FITRIANI LUMONGGA

    Dr. LITA FERIYAWATI

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    Endocrine System Parts

    yPituitary Gland

    y Thyroid

    y Parathyroids

    yAdrenal Glands

    y Pineal Body

    y Reproductive Glands

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    PITUITARY

    GLAND

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    The pituitary gland or hypophysis is a smallgland about 1 centimeter in diameter or the size

    of a pea.

    It is nearly surrounded by bone as it rests in the

    sella turcica, a depression in the sphenoid bone.

    The gland is connected to the hypothalamus of

    the brain by a slender stalk called the

    infundibulum.

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    There are two distinct regions in the gland:

    - the anterior lobe (adenohypophysis) and- the posterior lobe (neurohypophysis).

    The activity of the adenohypophysis is controlled

    by releasing hormones from the hypothalamus.

    The neurohypophysis is controlled by nerve

    stimulation

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    THE ANTERIOR LOBE OF HYPOPHYSE

    is the larger and is somewhat kidney-shaped, the

    concavity being directed backward and

    embracing the posterior lobe.

    It consists ofa pars anteriorand a pars

    intermedia, separated from each other by a

    narrow cleft, the remnant of the pouch or

    diverticulum.

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    The pars anterioris extremely vascular and

    consists of epithelial cells of varying size andshape, arranged in cord-like trabecul or alveoli

    and separated by large, thin-walledbloodvessels.

    The pars intermedia is a thin lamina closely

    applied to the body and neck of the posterior

    lobe and extending onto the neighboring parts of

    the brain; it contains few bloodvessels andconsists of finely granular cells between which

    are small masses of colloid material.

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    The pineal organ is small, weighing little morethan 0.1 gram and only about 5 to 8 millimeters

    long

    It lies deep within the brain between the two

    cerebral hemispheres and above the thirdventricle of the spinal column.

    It has a rich supply of adrenergic nerve fibers

    that greatly influence its secretions

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    Unpaired gland very variable , frequentlyasymmetrical gland and highly vascular

    Location: ant neck at C5-T1, overlays 2nd4th tracheal rings

    Avg width: 12-15 mm (each lobe)

    Avg height: 50-60 mm long

    Avg weight: 25-30 g in adults (slightly more inwomen)

    enlarges during menstruation and pregnancy

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    This gland is found in the neck inferior to (below)

    the thyroid cartilage (also known as theAdam'sapple in men) and at approximately the same

    level as the cricoid cartilage

    The thyroid gland is a butterfly shaped organ and

    is composed of two cone-like lobes or wings:

    lobus dexter(right lobe) and lobus sinister(left

    lobe), and is also connected with the isthmus

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    The organ is situated on the anterior side of the neck,

    lying against and around the larynx and trachea,

    reaching posteriorly the oesophagus and carotid

    sheath.

    It starts cranially at the oblique line on the thyroid

    cartilage (just below the laryngeal prominence orAdam's apple) and extends inferiorly to the fifth or

    sixth tracheal ring.

    It is difficult to demarcate the gland's upper and lower

    border with vertebral levels because it movesposition in relation to these during swallowing.

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    The thyroid gland is covered by a fibrous sheath, thecapsula glandulae thyroidea, composed of an

    internal and external layer.

    The external layer is anteriorly continuous with the

    lamina pretrachealis fasciae cervicalis andposteriorolaterally continuous with the carotid

    sheath.

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    The gland is covered : Anteriorly with infrahyoid muscles

    Laterally with the sternocleidomastoid

    muscle.

    Posteriorly the gland is fixed to the cricoidand tracheal cartilage and cricopharyngeus

    muscle by a thickening of the fascia to form the

    posterior suspensory ligament of Berry

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    The thyroid isthmus is variable in presence and size,

    and can encompass a cranially extending pyramid

    lobe (lobus pyramidalis orprocessus pyramidalis),

    remnant of the thyroglossal duct.

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    VASCULAR

    ANATOMY

    ARTERIAL

    VEIN

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    ARTERIAL, There are three main arteries

    supplying the thyroid gland:

    Superior Thyroid Artery, a branch of the

    external carotid artery

    Inferior Thyroid Artery, a branch of the

    thyrocervical trunkThyroid Ima Artery (occasionaly),

    branching directly from the

    brachiocephalic trunk

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    VEIN, There are three main veins draining the

    thyroid gland:

    Superior Thyroid Veins, draining in the

    internal jugular vein

    Middle thyroid vein

    Inferior ThyroidV

    eins, draining via theplexus thyroideus impar in the left

    brachiocephalic vein.

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    PARATHYROID

    GLAND

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    y Usually two on each side (superior and inferior)

    y Situated on the dorsal surface of the thyroid

    gland

    y

    Form and size very variable, yellowish-browncolor and have uniform smooth and shining

    surface

    y Length 6-8mm, width 3-4mm, thickness

    1,5-2mm

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    PANCREAS

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    Pancreas is a mixed gland as it performs both

    endocrine and exocrine functions.

    Pancreas is an elongated, yellowish gland.

    It consists of lobules that secrete pancreatic

    juice.

    Interspersed at random among the lobules are

    Islets of langerhans, which produce hormones.

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    It presents for examination for a caput, a cauda

    and a cauda pancreatisThe caput fills up the concavity of the pars

    descendens and pars inferior duodeni and is

    intimately united with their walls

    Anterior and inferior surfaces are covered byperitoneum

    Ductus pancreaticus wirsungi begins as a delicate

    duct in the cauda , extends within the substance of

    the gland to the right to the caput and gradually

    enlarge as it receives numerous narrow branches

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    y Two small flat bodies, wich lie directly medial

    from and above the kidneys, one on each sidey The right is approximately triangular and sits

    more upon the upper pole of the kidney

    y The left approximately sickle-shaped and lies

    more upon the margo medial of the kidney

    y Facies posterior lies loosely upon the pars

    lumbalis diaphragmatis

    y

    Facies anterior wich is in relation on the rightside with the impressio suprarenalis hepatis and

    the v.cava inferior

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    There are two parts, each of which makeshormones and has a different function.

    y The outer part ( Adrenal Cortex)

    y

    The inner part (Adrenal Medulla)

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