Journal Reading CFS

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    Journal Reading

    Chronic FatigueSyndrome: An Update on

    Treatment in Primary CareHani Raoul Khouzam, MD, MPH

    Advisor: dr. Parlin Susanto,

    Sp.S

    Presentant: Togi Stanislaus

    Patrick (2010.061.137)

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    General ManagementPrinciples

    Treatment goals based on the stage andseverity of the disability

    Referral to subspecialists

    Individualized patient-centred treatmentplan with specific objectives

    Patient education

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    Non-pharmacologicalManagement

    To help the patient achieve anappropriate balance between rest anddaily physical and mental activities

    Pacing Approach

    Most helpful

    Exercise graded, supervised

    To find a level of activity at which patientsfeel comfortable

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    Relaxation Techniques

    Can be used to manage pain, sleepproblems, and co-occuring stress or anxiety

    Guided imagery and breathing exercise during periods of rest

    Diet

    Well-balanced diet

    Eating regularly

    Self-help Groups

    Benefit instil ho e, offer an o ortunit

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    Cognitive-behavioural Therapy (CBT)

    Patients perform a cognitive assignmentthat entails gathering background details

    and identifying automatic thoughts andcognitive errors

    Challenge their perception of illness andgenerate alternative ways to view their

    problems and to cope with their symptoms

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    Mindfulness-based Cognitive-behaviouralTherapy (MCBT)

    Based on mind-body interaction and on

    practicing mindfulness meditation

    How to focus on the present moment andact with purpose rather than letting

    judgements about past events or fearsabout what may happen in the future affectcurrent feeling helps patients respondpositively

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    Education and Employment

    Occupational health services, disabilityservices, home education services

    To initiate flexible adjusments to work orstudies to help patients resume theiremployment or education wheneverpossible

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    Treatment of Co-occuringConditions

    Depression

    Mild moderate CBT, antidepressantmedication

    Psychiatric consultation severe orchronic depression, suicidal intentions,social isolation, poor symptom control

    TCA : amitriptyline, desipramine,nortriptyline

    SSRIs : fluoxetine, paroxetine, sertraline

    SNRIs : venlafaxine, duloxetine

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    Anxiety

    Benzodiazepines patient education

    SSRIs and SNRIs more advisable

    Sleep Disturbances

    Sleep hygiene techniques regulatingtimes of going to bed and getting up,relaxing during the day, controlling sleepenvironment

    Underlying sleep disorder low dose

    antidepressant (amitriptyline, trazodone, ormirtazapine)

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    Pain

    Acetaminophen and NSAIDs

    Phenytoin, gabapentin, divalproex sodiumneuropathic pain

    Muscle relaxants (cyclobenzaprine),antispasmodics (baclofen) panful muscle

    spasmsOpiates is not recommended in a primary

    care setting

    Transcutaneous electrical nerve stimulation

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    Controversial and ExperimentalTherapies

    CNS Stimulants

    Methylphenidate reduce fatigue andimprove mental concentration in patients

    with ADHD and CFSModafinil increase wakefullnes

    D-Ribose

    Significantly ameliorate symptoms of CFSwith particular benefit in participantsenergy level and overall sense of well being

    Not recommended in primary care setting

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    TERIMA KASIH