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Commentary
Components of Preparedness: A Study Tool for the NMTCB Examination
Ann M. Steves, Karen L. Blondeau and Martha W. Pickett
Nuclear Medicine Technology Certification Board, Atlanta, Georgia
Objective: Preparedness is vital for the successful completion of the NMTCB examination. Methods: The NMTCB has developed a set of statements called the Components of Preparedness (COP) that are designed to provide additional information about examination content. The COP statement for each task in the 1991 validated task analysis includes a definition of the content base, the knowledge required to perform the task and one or more taxonomy levels. The validated task analysis appears in an earlier JNMT article. Results: Three taxonomy levels are defined that are used to assess the examinee's intellectual preparedness to practice entry-level nuclear medicine technology. Conclusion: By testing an examinee's various levels of understanding, the NMTCB hopes to ensure the quality of certified nuclear medicine technologists and maintain the highest standards possible. Key Words: Components of Preparedness, comprehension, application, analysis, NMTCB.
J Nucl Med Techno/1994; 22:7~92
The Nuclear Medicine Technology Certification Board (NMTCB) uses a validated task analysis to ensure that the nuclear medicine technology examination's content reflects current practice (1-5). The validated task analysis consists of a task list of entry-level responsibilities, an equipment list and a procedures list. The tasks are identified by nuclear medicine practitioners (technologists, physicians, physicists and radiopharmacists) as being essential to success as an entry-level nuclear medicine technologist. The equipment list is an inventory of nuclear medicine instrumentation and auxiliary devices used to accomplish certain tasks identified on the task list. The procedures list identifies the clinical examinations typically performed by entry-level technologists. Thus, the task analysis defines the subject matter included on the examination and provides direction to the examination developers, item writers and examinees. At
For correspondence or reprints contact: Ann M. Steves, NMTCB, 2970 Clairmont Rd., Suite 610, Atlanta, GA 30329.
VOLUME 22, NUMBER 2, JUNE 1994
present, there are 92 tasks included in the task analysis and tested on the NMTCB examination (5).
To complement and expand upon the 92 tasks, the NMTCB has also developed the Components of Preparedness (COP) statements. These statements are intended to provide additional information to examinees and item writers about examination content related to each task. The COP statement for each task includes a definition of the content base, the knowledge required to carry out the task and one or more taxonomy levels, i.e., statements that describe the level of thought processes needed to complete the task successfully.
For purposes of the NMTCB certification examination, three taxonomy levels in the cognitive area are defined: comprehension, application and analysis. These three levels are based on a classification of educational objectives developed by Bloom eta!. (6) and are used to evaluate the examinee's intellectual preparedness to practice nuclear medicine technology. Skills such as knowledge, understanding and reasoning are all evaluated. Characteristics of each taxonomy level are described in Table 1.
Certain tasks involve thought processes at the comprehension level only, or at the comprehension and application levels only. Therefore, not all tasks have COP statements for all three taxonomy levels. For example, tasks related to maintaining written records only involve the comprehension level because the information to be recorded is defined in the relevant regulation and is not determined by a staff technologist. However, thought processes are hierarchical, i.e., they range from the simplest thought process of comprehension, to the more complex processes of application and analysis. Each higher classification includes the lower level thought processes. For instance, posting appropriate signs in radiation areas to comply with NRC regulations includes both identifying the signs used to post radiation areas (comprehension) and choosing the appropriate sign based on the measured radiation level (application).
The NMTCB examination is developed accordirtg to the -taxortomy levels, and attempts to test at the highest taxonomy level defined for a particular task. In the previous example, test questions are written at the application level to
79
Level
Comprehension
Application
Analysis
TABLE 1 Characteristics of Taxonomy Levels
Characteristics
• Most basic level of understanding and remembering. • Involves recall, recognition or understanding of facts, specifics or patterns. • Refers to a basic type of understanding or comprehension, but relationships or implications of such information
to other information are not involved. • May involve recognizing information presented in graph form. • Behavior terms that may fall under this category include restate, recognize, remember, express, identify, recall
and translate.
• Requires comprehension as well as the ability to apply knowledge in a novel situation. • Involves identifying the operation necessary for a problem or context and performing them. • May involve recognizing and applying technical principles, ideas, theories and formulas in a novel context. • May involve interpreting graphs or images. • Behavior terms that may fall under this category include interpret, employ, illustrate, practice, sketch, predict,
use and apply.
• Requires both comprehension and application as well as analysis of a concept, principle or idea. • Involves separating a concept, principle or idea into its component parts and identifying relationships among
the parts. • May involve combining concepts, principles or ideas into a new pattern or structure. • Involves evaluation of an image or procedure to determine accuracy or errors. • Involves reducing complex expressions into simpler or more basic expressions. • Involves comparing and contrasting, identifying similarities and differences among concepts, principles or ideas. • Behavior terms that may fall under this category include compare, contrast, diagram, examine, analyze,
construct and relate.
test the examinee's ability to choose the correct sign based on specific information given in the test question about the area to be posted. Sometimes taxonomy levels for certain tasks, particularly application and analysis, overlap because it is difficult to clearly define where one level ends and another begins. For example, all mathematical calculations are applications of formulas and are considered to be at the application taxonomy level. In certain instances, the result of a calculation must be interpreted or applied by the examinee to a given situation. Then, the taxonomy level is designated as analysis. Calculating a chi-square value, for instance, involves thought processes at the application level, but interpreting the value to determine whether an instrument is properly functioning involves analytical thinking.
Samples of former test questions paired with the related task and COP statement have been distributed to all program directors for the past three years. For additional information, contact the NMTCB office at (404) 315-1739.
REFERENCES
1. Nuclear Medicine Technology Certification Board. NMTCB certification
examination validation report. J Nucl Med Techno/1982;10:210-222.
2. Nuclear Medicine Technology Certification Board. NMTCB critical task
validation study: identification of entry-level domain. J Nucl Med Techno/
1984; 12:192-200.
3. Nuclear Medicine Technology Certification Board. Reexamination of
NMTCB board critical task survey: a response to changing entry-level practice. J Nucl Med Techno/ 1986;14:228-234. The COP statements containing the content base and tax
onomy levels defined for each task in the latest validated NMTCB task analysis appear on the following pages. The statements have been used extensively by item writers to develop questions for the examination and should be useful to students and faculty of educational programs in preparing for the NMTCB examination.
80
4. Blosser N, Drew H, Steves A. NMTCB task analysis validation update. J Nucl Med Techno/1988;16:216-221.
5. Blondeau KL, Hartnett SD, Pickett MW, et al. Nuclear Medicine Technology Certification Board (NMTCB) 1991 critical task analysis validation report. J Nucl Med Techno/1992;20:173-176.
6. Bloom BS, et al. Taxonomy of educational objectives: handbook I, cog
nitive domain. New York, NY: David McKay Company, Inc.; 1956.
.JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY
NMTCB COMPONENTS OF PREPAREDNESS
1. Post appropriate signs in designated areas to comply with NRC regulations.
CONTENT BASE 1. NRC regulations 2. Restricted and unrestricted areas
maximum permissible radiation levels (exposure limits)
3. Radiation surveys a. Survey meters b. Area monitoring
COMPREHENSION Identify appropriate signs for posting in designated radiation areas.
APPLICATION Choose appropriate radiation signs for areas where radioactivity is stored or used.
ANALYSIS None
2. Package radioactive materials according to regulations.
CONTENT BASE 1. Regulatory requirements
a. NRC b. DOT
2. Radiation surveys of packages a. Survey meters b. Surface contamination
3. Transport index 4. Packaging types (materials)
COMPREHENSION State the regulatory requirements for packaging radioactive materials
APPLICATION Determine appropriate methods for packaging radioactive materials according to regulations.
ANALYSIS None
3. Maintain accurate, written radiation safety/protection records to comply with regulations.
CONTENT BASE Note: This applies to FDA, NRC and DOT regulations.
1. Personnel exposure documents 2. Wipe tests 3. Area radiation surveys 4. Survey instruments
VOLUMI! 22, NUMBI!R 2, .JUNE 1994
GROUP 1: RADIATION SAFETY
5. Radiopharmaceutical receipt, transfer and disposal
6. Management of radioactive spills
COMPREHENSION Identify regulations regarding written records for radiation safety/ protection procedures and the information to be recorded to comply with regulations.
APPLICATION None
ANALYSIS None
4. Use radiation monitoring devices. CONTENT BASE
1. NRC regulations 2. Types and characteristics of
personnel monitoring devices 3. Properties of nuclear radiation 4. Radiation surveys 5. Exposure limits for hospitalized
patients COMPREHENSION Identify various personnel monitoring devices and explain their proper use.
APPLICATION Determine appropriate personnel monitoring devices for various contexts. Determine appropriate patient monitoring devices given specific circumstances.
ANALYSIS None
S. Review monthly personnel exposure records with regard to maximum permissible radiation dose limits.
CONTENT BASE 1. NRC regulations 2. Absorbed dose units 3. Maximum permissible radiation
doses (MDP) 4. Types and characteristics of
personnel monitoring devices COMPREHENSION State maximum permissible radiation dose limits for personnel.
APPLICATION Examine monthly personnel exposure reports to determine if MPD limits have been exceeded.
ANALYSIS Analyze instances of increased radiation exposure and recommend measures to reduce or eliminate unnecessary exposure.
6. Take appropriate measures to reduce radiation exposure when necessary.
CONTENT BASE 1. NRC regulations 2. Properties of nuclear radiation 3. Radiation protection techniques
a. Time b. Distance c. Shielding
4. ALARA concept 5. Types and characteristics of
personnel monitoring devices 6. Radiation surveys
COMPREHENSION Identify appropriate measures to reduce radiation levels and to keep exposure as low as reasonably achievable.
APPLICATION Recommend appropriate techniques to reduce radiation levels and to keep exposure as low as reasonably achievable in various contexts.
ANALYSIS Examine instances of increased radiation levels and recommend measures to reduce them.
7. Notify the appropriate authority of excessive radiation exposure.
CONTENT BASE 1. NRC regulations 2. Personnel monitoring 3. Radiation surveys
a. Survey meters b. Area monitoring c. Patient monitoring
4. Acceptable activity ranges for diagnostic and therapeutic procedures
5. Maximum permissible radiation doses for personnel
COMPREHENSION Identify unacceptable levels of radiation exposure and the appropriate authority to notify.
81
APPLICATION Determine if excessive radiation exposure has occurred and select the appropriate authority to notify.
ANALYSIS None
8. Notify the appropriate authority of misadministration when applicable.
CONTENT BASE 1. Regulatory requirements
a. NRC b. FDA
2. Approved routes of radiopharmaceutical administration
3. Acceptable activity range for diagnostic and therapeutic radiopharmaceuticals
4. Approved FDA radiopharmaceuticals
COMPREHENSION Identify a radiopharmaceutical misadministration and the appropriate authority to notify.
APPLICATION Determine if a radiopharmaceutical misadministration has occurred and select the appropriate authority to notify.
ANALYSIS None
9. Use proper shielding and the invene square law to reduce radiation exposure.
CONTENT BASE 1. NRC regulations 2. Properties of nuclear radiation 3. Radiation protection techniques
a. Time b. Distance c. Shielding
4. ALARA concept 5. Types and characteristics of
personnel monitoring devices 6. Radiation surveys
COMPREHENSION Identify appropriate measures to reduce radiation levels and to keep exposure as low as reasonably achievable.
APPLICATION Recommend appropriate techniques to reduce radiation levels and to keep exposure as low as reasonably achievable in various contexts.
ANALYSIS Examine instances of increased radiation levels and recommend measures to reduce them.
10. Use proper methods for the storage of radiopharmaceuticals.
CONTENT BASE I. Regulatory requirements
82
a. NRC b. FDA
2. Radiation protection techniques a. Beta emitters b. Gamma emitters
3. Storage requirements of radiopharmaceuticals a. Temperature b. Light c. Humidity d. Ventilation
COMPREHENSION Identify proper storage methods for radiopharmaceuticals.
APPLICATION Determine proper storage conditions for a given radiopharmaceutical.
ANALYSIS Analyze consequences of improper storage and alter storage methods accordingly.
11. Identify and use proper procedures for radiopharmaceuticals that pose special hazards.
CONTENT BASE I. Regulatory requirements
a. NRC b. FDA
2. Radiopharmaceutical characteristics a. Physical properties b. Radiation emissions
3. Radiation protection techniques COMPREHENSION Identify the radiopharmaceuticals that pose special hazards and identify proper procedures for handling those materials.
APPLICATION Determine proper procedures for handling a given radiopharmaceutical.
ANALYSIS Analyze circumstances contributing to special hazards associated with radiopharmaceuticals and alter procedures appropriately.
12. Instruct the patient, family and hospital stall' in radiation safety precautions after the administration of diagnostic and therapeutic radiopharmaceuticals.
CONTENT BASE I. Regulatory requirements
a. NRC b. FDA
2. Radiation safety practices 3. Patient communications 4. Patient and personnel
monitoring
COMPREHENSION Identify radiation safety precautions which should be conveyed to the patient, family and hospital staff following the administration of radiopharmaceuticals.
APPLICATION Choose appropriate instructions to be conveyed to the patient, family and hospital staff following the administration of diagnostic and therapeutic radiopharmaceuticals.
ANALYSIS None
13. Provide instruction on proper radiation emergency procedures to be followed.
CONTENT BASE 1. NRC regulations 2. Radiation safety practices 3. Decontamination procedures
COMPREHENSION Identify a radiation emergency.
APPLICATION Choose appropriate instructions in proper radiation emergency procedures to be followed until radiation personnel arrive.
ANALYSIS None
14. Perform wipe tests and area radiation surveys following a standardized schedule and format.
CONTENT BASE 1. NRC regulations 2. Properties of nuclear radiation 3. Survey instruments 4. Area monitoring-surveys and
wipe tests COMPREHENSION Identify the procedure for performing wipe tests and area radiation surveys.
APPLICATION Perform wipe tests and area radiation surveys with appropriate survey instrument and frequency.
ANALYSIS None
15. Follow required procedures for receipt of radioactive materials.
CONTENT BASE I. Regulatory requirements
a. NRC b. DOT
2. Package survey requirements 3. Survey instruments 4. Wipe tests
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY
COMPREHENSION Identify procedures for receipt of radioactive materials.
APPLICATION Determine appropriate procedure for receiving a package containing radioactive materials.
ANALYSIS None
16. Appropriately dispose of radioactive material.
CONTENT BASE 1. Regulatory requirements
a. NRC b. DOT
2. Disposal methods for radioactive liquids, solids and gases
3. Half-life 4. Survey meters
COMPREHENSION Identify disposal procedures solid, liquid and gaseous radioactive materials.
19. Maintain appropriate instrumentation quality control records to comply with regulatory requirements.
CONTENT BASE This task relates to regulations which require written records for the following instrumentation quality control: 1. Scintillation camera
a. Linearity b. Resolution c. Sensitivity d. Uniformity
2. Scintillation spectrometer a. Resolution b. Sensitivity c. Constancy (Chi square)
3. Dose calibrator a. Accuracy b. Constancy c. Geometry d. Activity linearity
4. Survey instruments a. Accuracy b. Constancy
5. Laboratory equipment a. Balances b. Pipets, precision and
accuracy c. Refrigerator/water bath
temperatures d. Centrifuge (tachometer and
timer)
COMPREHENSION Identify regulations regarding written records for instrumentation quality control and the information
VOLUME 22, NUMBER 2, .JUNE 1994
APPLICATION Determine the appropriate procedure for disposing of a radioactive material.
ANALYSIS None
17. Maintain a long-term storage area to allow for decay of radioactivity.
CONTENT BASE 1. NRC regulations 2. Disposal of radioactive waste 3. Posting requirements 4. Shielding 5. Other characteristics of a decay
storage area COMPREHENSION Identify the requirements of a longterm storage area for the decay of radioactive waste.
APPLICATION None
ANALYSIS None
GROUP II: INSTRUMENTATION
to be recorded to comply with regulations.
APPLICATION None
ANALYSIS None
20. Calibrate a scintillation spectrometer.
CONTENT BASE 1. Basic electronic nomenclature 2. Sodium iodide scintillation
detector system components 3. Sodium iodide scintillation
detector performance characteristics
4. Gamma ray spectra COMPREHENSION State the procedure for calibrating a scintillation counter.
APPLICATION Determine the correct calibration for a scintillation counter.
ANALYSIS None
21. Determine the percent energy resolution of a scintillation spectrometer.
CONTENT BASE 1. Basic electronic nomenclature 2. Sodium iodide scintillation
detector system components 3. Sodium iodide scintillation
detector performance characteristics
4. Gamma ray spectra
18. Use proper procedures for managing a radioactive spill.
CONTENT BASE 1. NRC regulations 2. Radioactive spill management
a. Containment: major, minor spills
b. Equipment 3. Decontamination procedures
a. Patient and personnel decontamination
b. Equipment c. Area decontamination
4. Waste disposal 5. Survey methods
COMPREHENSION Identify procedures for handling a radioactive spill.
APPLICATION Determine the appropriate procedures for containing and decontaminating a radioactive spill and for notifying the proper authority.
ANALYSIS None
5. Quality control of scintillation spectrometer
COMPREHENSION Define full width at half maximum (FWHM).
APPLICATION Determine the percent energy resolution of a scintillation spectrometer.
ANALYSIS Evaluate results of energy resolution determination.
22. Conduct sensitivity checks on the scintillation spectrometer or scintillation camera.
CONTENT BASE 1. Basic electronic nomenclature 2. Sodium iodide scintillation
detector system components 3. Sodium iodide scintillation
detector performance characteristics
4. Quality control of scintillation spectrometer/camera
COMPREHENSION Define sensitivity.
APPLICATION Determine the sensitivity of a scintillation spectrometer or scintillation camera.
ANALYSIS Analyze changes in sensitivity and determine cause.
83
23. Obtain background counts on a scintillation spectrometer.
CONTENT BASE 1. Basic electronic nomenclature 2. Sodium iodide scintillation
detector system components 3. Sodium iodide scintillation
detector performance characteristics
4. Quality control of scintillation spectrometer
COMPREHENSION Define background.
APPLICATION Determine background.
ANALYSIS Assess changes in background and determine cause of increased background.
24. Perform a chi-square test on a scintillation spectrometer.
CONTENT BASE 1. Basic electronic nomenclature 2. Sodium iodide scintillation
detector system components 3. Sodium iodide scintillation
detector performance characteristics
4. Quality control of scintillation spectrometer
5. Chi-square formula
COMPREHENSION Define chi-square and identify the procedure for performing a chisquare test.
APPLICATION Determine the chi-square value for a scintillation spectrometer.
ANALYSIS Evaluate chi-square results.
25. Adjust pulse-height analyzer (PHA) on the scintillation spectrometer or camera for the appropriate photopeak.
CONTENT BASE 1. Sodium iodide detector system
components. a. Scintillation spectrometer b. Scintillation cameras
2. Pulse-height analysis (PHA) 3. Gamma ray spectra 4. Basic electronic nomenclature
COMPREHENSION Define the purpose of the pulseheight analyzer.
APPLICATION Determine the appropriate PHA adjustment.
ANALYSIS Analyze operational problems caused by improper PHA adjustment.
84
26. Perform field uniformity check on the scintillation camera on a routine basis.
CONTENT BASE 1. Scintillation camera
a. Components b. Collimators c. Image display
2. Uniformity quality control 3. Scintillation camera performance
characteristics 4. Uniformity requirements for
SPECT COMPREHENSION
Define field uniformity. APPLICATION Determine the field uniformity of a scintillation camera.
ANALYSIS Analyze field uniformity images and differentiate source of nonuniformities.
27. Perform detector linearity check on a scintillation camera on a routine basis.
CONTENT BASE 1. Scintillation camera
a. Components b. Collimators c. Image display
2. Linearity quality control 3. Scintillation camera performance
characteristics COMPREHENSION
Define linearity. APPLICATION Determine the linearity of a scintillation camera.
ANALYSIS Analyze images for nonlinearity and assess cause.
28. Perform spatial resolution check on a scintillation camera on a routine basis.
CONTENT BASE 1. Scintillation camera
a. Components b. Collimators c. Image display
2. Resolution quality control 3. Scintillation camera performance
characteristics 4. Phantoms 5. SPECT center of rotation
COMPREHENSION Define spatial resolution.
APPLICATION Determine the spatial resolution of a scintillation camera.
ANALYSIS Analyze images to determine any loss of spatial resolution and assess causes for loss of resolution.
29. Assess performance of image recording equipment.
CONTENT BASE 1. Scintillation camera/computer
a. Image display multiformatter, CRT
b. Quality control of image recording devices
2. Film processor quality control 3. Photographic film characteristics
COMPREHENSION Identify the components of the image recording equipment and their function.
APPLICATION Determine the performance of image recording equipment.
ANALYSIS Analyze images for proper performance of image recording equipment and assess cause of improper performance.
30. Perform reference check on survey meter.
CONTENT BASE 1. NRC regulations 2. Survey meter quality control
COMPREHENSION Identify test to evaluate survey meter operation.
APPLICATION Determine the performance of a survey meter.
ANALYSIS Assess survey meter operation based on reference source test results.
31. Ascertain the activity linearity of the dose calibrator over the entire range of radionuclide activity to be used.
CONTENT BASE 1. NRC regulations 2. Dose calibrator
a. Operation b. Quality control
COMPREHENSION Define activity linearity.
APPLICATION Determine the activity linearity of a dose calibrator.
ANALYSIS Analyze activity linearity test results and assess dose calibrator performance.
32. Test accuracy of dose calibrator for commonly used radionuclides.
CONTENT BASE 1. NRC regulations 2. Dose calibrator
a. Operation b. Quality control
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY
COMPREHENSION Define accuracy
APPLICATION Determine the accuracy of a dose calibrator.
ANALYSIS Analyze accuracy test results and assess dose calibrator performance.
33. Check for constancy of dose calibrator using a long-lived radionuclide standard.
CONTENT BASE 1. NRC regulations 2. Dose calibrator
a. Operation b. Quality control
COMPREHENSION Define constancy.
APPLICATION Determine the constancy of a dose calibrator.
ANALYSIS Analyze constancy test results and assess dose calibrator performance.
34. Perfonn basic computer operations.
CONTENT BASE 1. Digital computer components
a. Hardware b. Software c. Peripheral devices
2. Computer operation a. Acquisition b. Data processing and analysis c. Display
3. SPECT reconstruction COMPREHENSION Define the following: peripheral devices, software and hardware.
APPLICATION Choose the appropriate computer routines for data acquisition, processing, display and retrieval.
ANALYSIS Analyze information obtained from a computer for accuracy and completeness.
35. Maintain proper environmental conditions for computer and associated equipment and supplies.
CONTENT BASE 1. Computer and associated
equipment operating conditions
VOLUME 22, NUMBER 2, .JUNE 1994
2. Data storage conditions COMPREHENSION
Identify proper environment for optimal computer operation and data storage.
APPLICATION Maintain appropriate environmental conditions for proper computer operation and data storage.
ANALYSIS None
36. Conduct temperature checks on water baths and refrigerators.
CONTENT BASE 1. Water bath operation and
maintenance 2. Refrigerator operation and
maintenance 3. Thermometer calibration
COMPREHENSION Identify the proper method for conducting temperature checks on water baths and refrigerator.
APPLICATION Determine the temperature of water baths and refrigerator using a properly calibrated thermometer.
ANALYSIS None
37. Operate centrifuge and conduct routine tachometer checks.
CONTENT BASE 1. Centrifuge components and
types of centrifuges 2. Computation of relative
centrifugal force 3. Quality control using a
tachometer COMPREHENSION Identify the appropriate type of centrifuge for the procedure being performed and the method for computing relative centrifugal force.
APPLICATION Calculate the relative centrifugal force given the rotating radius in em, and the rotating speed in rpm. Determine centrifuging time when the optimum speed cannot be obtained.
ANALYSIS None
38. Calibrate and use single-sample well counter.
CONTENT BASE 1. Basic electronic nomenclature 2. Sodium iodide scintillation
detector system components 3. Sodium iodide scintillation
detector performance characteristics
4. Gamma ray spectra 5. Quality control of a scintillation
counter 6. Characteristics of a standard
well detector 7. Counting geometry and
efficiency
COMPREHENSION State the procedure for calibrating a scintillation counter. Identify considerations about sample volume, counting geometry and amount of activity to be counted.
APPLICATION Determine the correct calibration for a scintillation counter. Use appropriate sample volume, counting geometry and activity.
ANALYSIS None
39. Perfonn film processor quality control.
CONTENT BASE 1. Automatic film processor
operation 2. Automatic film processor quality
control
COMPREHENSION Identify quality control procedures to monitor film processor performance.
APPLICATION Determine film processor performance using appropriate quality control procedures.
ANALYSIS Assess results of quality control procedures and initiate corrective measures as needed.
85
40. Store and maintain adequate supplies including kits to assure timely completion of patient studies.
CONTENT BASE 1. Inventory control
a. Usage rate b. Expiration date
2. Storage conditions for supplies 3. Ordering procedures 4. Patient scheduling
COMPREHENSION List type and quantity of supplies required and identify method for obtaining them.
APPLICATION
Determine supply needs to assure that patient studies arc scheduled on a timely basis.
ANALYSIS None
41. Maintain and operate auxiliary equipment identified in the equipment procedures list.
CONTENT BASE I. Safety requirements 2. Theory of operation 3. Quality control procedures
COMPREHENSION Identify and state the proper procedure to use auxiliary equipment required for imaging procedures.
APPLICATION Determine appropriate procedures to maintain and operate auxiliary equipment for imaging procedures.
ANALYSIS None
42. Schedule patient studies, ensuring appropriate sequence for multiple procedures, and interact with hospital stall' regarding special orders.
CONTENT BASE l. Imaging and nonimaging
procedures 2. Sequence of procedures 3. Special orders
a. Premedication b. Dietary restriction c. Specimen collection d. Other
4. Radiopharmaceuticals a. Effective half-life b. Energy ranges
5. Inventory controls 6. Communication skills
86
GROUP III: CLINICAL PROCEDURES
COMPREHENSION Identify appropriate patient scheduling sequences and special orders for procedures.
APPLICATION Determine the most appropriate and timely sequence for patient studies and any special orders required.
ANALYSIS Analyze patient scheduling difficulties and revise schedule accordingly.
43. Maintain appropriate patient procedure records.
CONTENT BASE 1. Regulatory requirements
a. NRC b. FDA
2. Written patient records and reports
COMPREHENSION Identify appropriate written records to be maintained for patient procedures.
APPLICATION None
ANALYSIS None
44. Receive patient and provide proper nursing care during nuclear medicine procedure.
CONTENT BASE 1. Communication skills 2. Basic nursing procedures
a. Body mechanics b. Vital signs c. Infection control d. First aid
3. Patient support devices a. Intravenous fluids b. Oxygen c. Foley catheter and drainage
bag d. ECG monitor e. Other
COMPREHENSION Identify basic nursing procedures.
APPLICATION Determine appropriate nursing care during procedure.
ANALYSIS Appraise a situation that requires nursing care be provided and determine the most appropriate action.
45. Maintain good communication with patient by explaining procedure, answering questions and listening to patient's comments.
CONTENT BASE 1. Knowledge of nuclear medicine
procedures 2. Communication skills 3. Medical ethics
COMPREHENSION Identify responsibilities of technologist in maintaining effective communication with patients.
APPLICATION Recommend appropriate communication with patients given a particular situation.
ANALYSIS None
46. Provide functionally safe and sanitary conditions for patient.
CONTENT BASE 1. Body mechanics 2. Infection control precautions 3. Medical legal aspects
COMPREHENSION Identify unsafe or unsanitary conditions.
APPLICATION Determine safe and sanitary conditions for patient.
ANALYSIS None
47. Recognize emergency conditions and determine patient's vital signs when necessary.
CONTENT BASE 1. Vital signs
a. Pulse rate b. Respiratory rate c. Blood pressure d. Temperature
2. Signs/symptoms a. Fainting b. Seizure c. Cardiopulmonary arrest d. Other
COMPREHENSION Identify normal values for vital signs and describe signs and symptoms of medical emergencies.
APPLICATION Recognize signs and symptoms of medical emergencies.
ANALYSIS Assess an emergency situation and .initiate appropriate action.
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY
48. Administer cardiopulmonary resuscitation and first aid when necessary.
CONTENT BASE 1. Vital signs 2. Signs/symptoms of
cardiopulmonary arrest 3. First aid techniques
COMPREHENSION Describe CPR and first aid techniques.
APPLICATION Determine patient condition and initiate CPR and/or appropriate first aid measures as indicated.
ANALYSIS None
49. Receive patient and verify patient identification and written orders for study.
CONTENT BASE 1. NRC regulations 2. Patient preparation 3. Medical legal aspects 4. Communication skills
COMPREHENSION Identify procedure for receiving patient and methods of verifying patient identification and written orders for study.
APPLICATION Determine appropriate methods to receive patients and verify patient identification and written order for study.
ANALYSIS None
50. Check procedural contraindications for study and obtain pertinent patient history.
CONTENT BASE 1. Communication skills 2. Medical/legal aspects 3. Patient preparation
a. Premedications b. Dietary restrictions c. Radiopharmaceutical
administration d. Other
4. Contraindications for nuclear medicine procedures
COMPREHENSION Identify contraindications and pertinent patient history for nuclear medicine studies.
APPLICATION Obtain pertinent patient history and determine if a contraindication for performing study exists.
ANALYSIS None
VOLUME 22, NUMBER 2, JUNE 1994
51. Wben necessary, obtain written informed consent to perform study.
CONTENT BASE 1. Regulatory requirements
a. FDA b. IND
2. Informed consent 3. Communication skills
COMPREHENSION Define informed consent.
APPLICATION Determine when informed consent is required.
ANALYSIS None
52. Prepare patient for procedure as required.
(NOTE: THIS APPLIES TO PREPARATIONS THAT OCCUR IN THE NUCLEAR MEDICINE DEPARTMENT AND ARE NORMALLY PERFORMED BY THE TECHNOLOGIST.) CONTENT BASE
1. Communication skills 2. Procedural requirements
COMPREHENSION Identify patient preparation required for nuclear medicine procedures.
APPLICATION Determine appropriate patient preparation to be performed for a specific procedure.
ANALYSIS Analyze consequences of inappropriate patient preparation and initiate corrective action.
53. Transfer patient from wheelchair/ stretcher to the imaging table.
CONTENT BASE 1. Communication skills 2. Body mechanics
COMPREHENSION Identify patient transfer techniques.
APPLICATION Determine appropriate transfer technique based on patient's condition and ability to cooperate.
ANALYSIS None
54. Administer the appropriate radiopharmaceutical by the proper route.
CONTENT BASE 1. Approved radiopharmaceuticals 2. Radiopharmaceutical
administration a. Approved routes b. Aseptic technique c. Bolus technique
3. Radiation safety COMPREHENSION Identify the appropriate radiopharmaceuticals for nuclear medicine procedures and the method of administration.
APPLICATION Determine the appropriate radiopharmaceutical and route of administration for a procedure.
ANALYSIS None
55. Discard contaminated materials in appropriate waste container.
CONTENT BASE 1. Regulatory requirements 2. Infection control precautions 3. Radiation safety practices
COMPREHENSION Identify the appropriate methods for discarding contaminated materials.
APPLICATION Determine which materials require special methods of disposal and discard them appropriately.
ANALYSIS None
56. Wait appropriate length of time after administration of the radiopharmaceutical to begin imaging.
CONTENT BASE 1. Radiopharmacology
a. Mechanisms of localization b. Biological and effective half
life c. Temporal relationship to
other medications d. Blood clearance rates
2. Procedural requirements COMPREHENSION Identify appropriate waiting period after radiopharmaceutical administration to begin imaging procedure.
APPLICATION Determine appropriate imaging time after radiopharmaceutical administration for a given procedure.
ANALYSIS Analyze consequences of early or delayed imaging and initiate corrective measures as appropriate.
57. Select and prepare proper instrument, computer and auxiliary equipment necessary to perform imaging procedures as indicated by protocol.
CONTENT BASE 1. Nuclear medicine procedures
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2. Imaging parameters 3. Data acquisition 4. Auxiliary equipment operation
COMPREHENSION Identify instruments and auxiliary equipment available for imaging procedures.
APPLICATION Determine the appropriate instrument, imaging and data acquisition parameters and auxiliary equipment necessary to perform an imaging procedure according to protocol.
ANALYSIS None
58. Place tbe patient in correct position, using supportive materials and immobilizers, at appropriate distance from detector for obtaining eacb view.
CONTENT BASE 1. Nuclear medicine procedures 2. Patient positioning
a. Anatomy b. Positioning terminology c. Immobilization d. Anatomical markers
COMPREHENSION Identify routine patient position for an imaging procedure.
APPLICATION Determine correct patient position for an imaging procedure, including correct detector-to-patient distance, using supportive materials and immobilizers as necessary.
ANALYSIS Evaluate images for possible positioning errors and initiate corrective measures.
59. Indicate appropriate anatomical landmarks for eacb view of a procedure.
CONTENT BASE 1. Nuclear medicine procedures 2. Anatomical landmarks 3. Patient positioning
COMPREHENSION Identify commonly used anatomical landmarks.
APPLICATION Determine the appropriate anatomical landmark to be used for each view of a procedure.
ANALYSIS None
60. Collect specimens according to imaging protocol if applicable.
CONTENT BASE 1. Nuclear medicine procedures
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2. Collection techniques for blood, urine, CSF, etc.
COMPREHENSION Identify procedures requiring specimen collection and describe collection procedure.
APPLICATION Determine appropriate time for specimen collection using appropriate container.
ANALYSIS None
61. Analyze image appearance or computer information for normal structure and artifacts making adjustments if necessary, and assuring correct information is supplied.
CONTENT BASE 1. Anatomy 2. Nuclear medicine procedures 3. Quality control procedures
COMPREHENSION Identify anatomical structures and other information to be included in a diagnostic study. Also identify common artifacts that may appear on the images.
APPLICATION Determine appropriate imaging parameters and data acquisition to deliver technically satisfactory diagnostic images and/or computer information.
ANALYSIS Assess diagnostic images and/or computer information for technical quality and initiate corrective measures if appropriate.
62. Perform any special views as required.
CONTENT BASE 1. Nuclear medicine procedures 2. Patient positioning
a. Anatomy b. Markers
COMPREHENSION Identify need for special views.
APPLICATION Recommend special views for an imaging procedure.
ANALYSIS Assess images and determine most appropriate special views to aid image interpretation.
63. Retrieve and process patient data acquired on a computer.
CONTENT BASE 1. Data retrieval 2. Data processing techniques
COMPREHENSION Identify techniques to retrieve and process data.
APPLICATION Determine the appropriate technique to retrieve and process computer data for a diagnostic procedure.
ANALYSIS Analyze processed patient data and assess appropriate computer manipulation for interpretation.
64. Process film according to manufacturer's specifications and film processor optimum operation.
CONTENT BASE 1. Film processor operation 2. Film types and properties 3. Film processing quality control
COMPREHENSION Identify manufacturer's specifications for proper film processing and recognize optimum operation of film processor.
APPLICATION Determine methods to properly process film and operate automatic film processor.
ANALYSIS Examine images for problems related to film processing or automatic film processor problems and initiate corrective measures if appropriate.
65. Record information relative to any special circumstances aft"ecting tbe procedure as needed.
CONTENT BASE 1. Nuclear medicine procedures 2. Quality control procedures
COMPREHENSION Identify conditions which may affect the procedure and recognize the necessity of recording that information.
APPLICATION Recommend information to be recorded relative to special circumstances affecting the procedure.
ANALYSIS Differentiate those circumstances that would affect the procedure.
66. Determine hematocrit. CONTENT BASE
1. Definition of hematocrit 2. Method of obtaining hematocrit 3. Micro hematocrit centrifuge
operation
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COMPREHENSION Define hematocrit and identify when utilized in nuclear medicine procedures.
APPLICATION Determine hematocrit.
ANALYSIS None
67. Collect and process patient samples appropriately.
CONTENT BASE 1. Nuclear medicine procedures 2. Collection techniques for blood
and urine 3. Sample processing and storage
COMPREHENSION Identify type of specimen required for given procedure; describe collection, processing and storage procedures.
APPLICATION Determine appropriate time for specimen collection; collect, process and store specimen as required.
ANALYSIS None
68. Prepare a standard dilution.
CONTENT BASE 1. Standard preparation
a. Radiopharmaceutical and activity required
b. Amount of dilution required based on counting rate limitations of instrumentation
2. Dilution technique a. Calculation of dilution
concentration b. Solvents and wetting
solutions c. Use of volumetric glassware
and pipets
COMPREHENSION Identify necessary equipment, solvents and volumes need to prepare a standard dilution.
APPLICATION Determine the appropriate dilution of a standard for a given procedure and calculate the amount of sample and solvent required.
ANALYSIS Analyze effects of improper dilution on patient results.
VOLUME 22, NUMBER 2, JUNE 1994
69. Prepare patient specimens for analysis.
CONTENT BASE 1. Equilibration to room
temperature 2. Lab equipment e.g., pipets, etc. 3. Protocol
COMPREHENSION Identify materials necessary to prepare patient specimens.
APPLICATION Determine protocol to be used for patient specimen preparation.
ANALYSIS None
70. Count patient samples for statistically significant number of counts.
CONTENT BASE 1. Counting statistics 2. Effect of background 3. Level of activity to be counted
COMPREHENSION Identify count required for statistical significance.
APPLICATION Determine counts or time required to reach statistical significance for a given set of samples.
ANALYSIS None
71. Cboose correct detector-patient distance for external counting and count for a statistically significant number of counts.
CONTENT BASE 1. Collimator characteristics 2. Counting statistics 3. Effect of background
COMPREHENSION Identify the appropriate patientdetector distance and the total count required for statistical significance.
APPLICATION Determine appropriate detectorpatient distance and counting times given a specific situation.
ANALYSIS None
72. Review nonimaging procedures for possible technical errors tbat may alter results.
CONTENT BASE 1. Random errors
a. Human variables b. Mechanical variables (pipets,
centrifuge, etc.)
c. Environmental variables (timing, temperature)
2. Systematic errors 3. Precision
a. Standard deviation b. Coefficient of variation
4. Accuracy COMPREHENSION Identify variables that can cause random and systematic errors.
APPLICATION Determine standard deviation and coefficient of variation of data points.
ANALYSIS Analyze data to differentiate acceptable from unacceptable data and determine source of error.
73. Perform calculations, as required, to determine final results for nonimaging procedures.
CONTENT BASE 1. Calculations 2. Graphing techniques
a. Data presentation on linear/ semi-log plot
b. Derivation of half-time and slope
COMPREHENSION Identify formula and/or graph paper required to calculate results of an nonimaging procedure.
APPLICATION Determine final results of a given nonimaging procedure using the appropriate formulae and/or graphing technique.
ANALYSIS None
74. Report botb patient calculated values and tbe reference range for nonimaging procedures.
CONTENT BASE 1. Patient records and reports
a. Contents b. Medicolegal considerations
2. Reference ranges COMPREHENSION Identify the appropriate information to be reported for a nonimaging procedure.
APPLICATION Determine the appropriate information to be reported for a nonimaging procedure.
ANALYSIS None
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75. Assemble and elute a radionuclide generator using aseptic technique.
CONTENT BASE 1. Shielding considerations 2. Types of generators ("wet" vs.
"dry" column) a. Operation b. Elution technique c. Generator yield (volume and
activity) 3. Aseptic technique 4. Radiation protection practices
COMPREHENSION Describe the assembly and operation of a radionuclide generator. Define aseptic technique.
APPLICATION Determine the appropriate elution technique for a particular generator and elute it using aseptic technique and appropriate radiation protection.
ANALYSIS Assess operational problems and determine most appropriate corrective action.
76. Assay the activity of the generator eluate using a dose calibrator and affix label.
CONTENT BASE 1. NRC regulations 2. Units of radioactivity 3. Dose calibrator operation 4. Vial label
COMPREHENSION Identify methods used to assay generator eluate and information that must appear on the label.
APPLICATION Determine the appropriate procedure for assaying generator eluate using a dose calibrator and the appropriate information for the vial label.
ANALYSIS Analyze circumstances contributing to improper assay of generator eluate in a dose calibrator and alter procedures accordingly.
77. Check the generator eluate for radionuclide and chemical contamination.
CONTENT BASE 1. Regulatory requirements
a. NRC b. USP
2. Dose calibrator operation 3. Units of radioactivity 4. Molybdenum-99 breakthrough
and Al+3 testing
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GROUP IV: RADIOPHARMACY
5. Allowable limits of 99Mo and Al+3
COMPREHENSION Define radionuclidic and chemical purity and state the allowable limits of 99Mo and Al+3 in generator eluate.
APPLICATION Determine the appropriate procedure to check the generator eluate for radionuclide and chemical contamination.
ANALYSIS Analyze circumstances leading to radionuclidic and chemical contamination and recommend methods for eliminating and/or minimizing contamination.
78. Review the daily work schedule to plan radiopharmaceutical needs.
CONTENT BASE 1. Patient scheduling
a. Match procedure with appropriate radiopharmaceutical
b. Time interval between radiopharmaceutical administration and procedure
c. Length of time to complete procedure
2. Activity ranges for diagnostic procedures
3. Effect of radioactive decay and shelf-life on available radiopharmaceutical inventory
COMPREHENSION Identify the radiopharmaceutical and activity range for each procedure required.
APPLICATION Determine radiopharmaceutical needs required to complete daily work schedule based on shelf-life and decay.
ANALYSIS Adjust daily work schedule to use available radiopharmaceutical inventory effectively.
79. Prepare radiopharmaceutical compounds.
CONTENT BASE 1. Kit procedures and techniques
a. Activity calculations b. Activity and volume limits c. Aseptic technique
2. Preparation of compounds 3. Operation of dose calibrator 4. Radiopharmaceutical quality
control results a. pH b. Color c. Clarity
d. Particle size e. Radiochemical purity
COMPREHENSION Describe the preparation of a specified 99mTc-labeled radiopharmaceutical compound.
APPLICATION Determine the appropriate preparation of a specified radiopharmaceutical compound.
ANALYSIS Analyze quality control results to determine quality of prepared radiopharmaceutical.
80. Determine the total volume and radioactivity to be added to a radiopharmaceutical kit within activity limits.
CONTENT BASE 1. Activity and chemical limits in
kit preparation 2. Activity/volume calculations
COMPREHENSION Identify the volume and activity of generator eluate to be added to a radiopharmaceutical kit.
APPLICATION Determine the total volume and radioactivity to be added to a radiopharmaceutical kit within activity limits.
ANALYSIS Analyze consequences of the addition of inappropriate volume or activity to a radiopharmaceutical kit.
81. Check total activity in radiopharmaceutical reaction vials with a dose calibrator.
CONTENT BASE 1. Activity limits in kit preparation 2. Dose calibrator operation 3. Units of activity
COMPREHENSION Identify method for determining total activity in a radiopharmaceutical reaction vial.
APPLICATION Determine the total activity in radiopharmaceutical reaction vials using a dose calibrator.
ANALYSIS None
82. Calculate the concentration of radioactivity of a compound and label vial as to d~te, time of preparation, lot number, concentration and volume.
CONTENT BASE 1. Regulatory requirements
a. NRC
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b. USP 2. Units of activity 3. Radiopharmaceutical
concentration calculation COMPREHENSION Identify appropriate labeling information for radiopharmaceutical preparations and how to calculate concentration of radioactivity.
APPLICATION Calculate the concentration of radioactivity of a radioactive compound and label vials with the correct date, time of preparation, lot number, concentration and volume.
ANALYSIS None
83. Check all radiopharmaceutical preparations for proper pH, color, clarity and particle size as appropriate.
CONTENT BASE 1. Radiopharmaceutical quality
control a. pH testing b. Visual inspection c. Microscopic inspection
COMPREHENSION Identify the procedures for checking radiopharmaceutical preparations for pH, color, clarity and appropriate particle size.
APPLICATION Determine the appropriate quality control procedures for a specific radiopharmaceutical preparation.
ANALYSIS Analyze circumstances leading to improper particle size, pH color or clarity of a radiopharmaceutical preparation and assess whether patients and/or nuclear medicine procedures would be affected adversely.
84. Determine the radiochemical purity of radiopharmaceutical preparations by chromatography.
CONTENT BASE 1. USP Regulations 2. Radiochemical purity testing
a. Chromatography b. Acceptable limits of
radiochemical impurities COMPREHENSION Define radiochemical purity and state the acceptable limits of radiochemical impurities for radiopharmaceuticals.
APPLICATION Determine the appropriate method to evaluate the radiochemical purity of a specified radiopharmaceutical.
VOLUME 22, NUMBER 2, .JUNE 1994
ANALYSIS Examine chromatography results to determine if radiochemical purity of preparation is within acceptable limits.
85. Verify label on radiopharmaceutical vial, including concentration, specific activity, total activity, lot number, assay tie and date.
CONTENT BASE 1. Regulatory requirements
a. NRC b. USP
2. Definition of label contents a. Concentration b. Specific activity c. Total activity d. Assay time and date
COMPREHENSION Identify the appropriate information to appear on the label of a radiopharmaceutical vial.
APPLICATION Determine the concentration, specific activity, total activity, lot number, assay time and date from the radiopharmaceutical vial label.
ANALYSIS None
86. Calculate activity to be administered for diagnostic or therapeutic procedures.
CONTENT BASE 1. NRC regulations 2. Units of activity 3. Vial label contents (total
activity, total volume, etc.) 4. Determination of elapsed time 5. Activity calculation 6. Acceptable activity range for
diagnostic and therapeutic procedures
COMPREHENSION Identify the formula to calculate activity to be administered for a diagnostic or therapeutic procedure.
APPLICATION Calculate activity to be administered for diagnostic or therapeutic procedures.
ANALYSIS None
87. Determine the volume or number of capsules of the radiopharmaceutical required for diagnostic and therapeutic procedures.
CONTENT BASE 1. NRC regulations 2. Units of activity
3. Vial label contents (total activity, total volume, etc.)
4. Determination of elapsed time 5. Activity calculation 6. Acceptable activity range for
diagnostic and therapeutic procedures
7. Volume or capsule determination
COMPREHENSION Identify the formula to determine the volume or number of capsules to be administered for a diagnostic or therapeutic procedure.
APPLICATION Calculate the volume or number of capsules to be administered for a diagnostic or therapeutic procedure.
ANALYSIS None
88. Withdraw correct volume of the radiopharmaceutical into a syringe using aseptic technique and proper radiation safety precautions.
CONTENT BASE 1. Aseptic technique 2. Radiation protection techniques 3. Venipuncture materials
COMPREHENSION Describe proper preparation of a unit dose radiopharmaceutical in a syringe including aseptic technique and radiation safety precautions.
APPLICATION Determine the proper procedure for withdrawing an accurate volume of radiopharmaceutical into a syringe using aseptic technique and radiation safety precautions.
ANALYSIS None
89. Using a dose calibrator, verify the activity to be administered in the dispensed preparation.
CONTENT BASE I. NRC regulations 2. Dose calibrator operation 3. Activity units 4. Activity range for diagnostic and
therapeutic procedures COMPREHENSION Describe how to verify the activity of a radiopharmaceutical using a dose calibrator.
APPLICATION Determine the activity of a radiopharmaceutical to be administered using a dose calibrator.
ANALYSIS None
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90. Verify that radionuclide impurity limits are not exceeded in the dispensed preparation.
CONTENT BASE 1. Regulatory requirements
a. NRC b. USP
2. Radionuclide purity testing 3. Acceptable limits of radionuclide
impurities 4. Dose calibrator operation 5. Multichannel analyzer operation
COMPREHENSION I~e~tify radionuclide impurity hm1ts and methods for their determination.
APPLICATION Determine the appropriate methods to evaluate radiopharmaceutical preparations for radionuclidic impurities and confirm that limits are not exceeded.
ANALYSIS Analyze situations in which radionuclidic impurity limits are exceeded and recommend remedial measures.
91. Maintain appropriate radiopharmaceutical preparation and administration records to comply with regulatory requirements.
CONTENT BASE 1. Regulatory requirements
a. NRC b. USP
2. Generator eluate assay
92
a. Dose calibrator/whole vial assay
b. Radionuclide and chemical contamination
3. Radiopharmaceutical kit preparation a. Volume and activity
calculations b. Volume of generator eluate
used c. Total activity assay
4. Radiopharmaceutical quality control a. pH b. Color c. Clarity d. Particle size e. Radiochemical purity
5. Patient radiopharmaceutical administration a. Name b. Examination c. Activity d. Volume e. Lot number f. Time and date g. Misadministration
COMPREHENSION Id~ntify regulations regarding wntten records for radiopharmaceutical preparation and administration and the information to be recorded to comply with regulations.
APPLICATION None
ANALYSIS None
92. Transfer radioactive gas or liquid into administration equipment if appropriate.
CONTENT BASE 1. Operation of radioactive gas/
aerosol administration equipment
2. Radiation safety precautions COMPREHENSION Identify the appropriate procedure for loading radioactive gas/liquid into administration equipment.
APPLICATION Choose the appropriate method for loading radioactive gas into administration equipment given specific circumstances, using appropriate radiation safety precautions.
ANALYSIS None
93. Label cells with a radiopharmaceutical according to protocol for procedure.
CONTENT BASE 1. Labeling procedure
a. Lab equipment required b. Anticoagulants c. Chemical reactions to stop
tagging d. Cell washing e. Radiopharmaceuticals
required 2. Aseptic technique 3. Centrifuge operation
COMPREHENSION Identify appropriate blood components and equipment necessary to label cells with a radiopharmaceutical.
APPLICATION Determine appropriate procedure for labeling blood cells with a given radiopharmaceutical.
ANALYSIS None
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