Experts of Simulated Moving Bed Chromatography and Supercritical Fluid Technology

Jope Technology Co., LTD is one of the top leaders in offering services on Simulated Moving Bed (SMB) and supercritical fluid technology. From process development to manufacturing and on-site installation, Jope is committed in offering high quality and competitive price to meet the separation and purification needs of pharmaceutical, nutraceutical, and other industries.

Established in Taiwan, Jope is gathered by a group of experts with over 10 years of experiences cultivating in the field of SMB chromatography. In addition to that, our engineering department also possesses more than 20 years of expertise in supercritical fluid technology (SF) and innovatively designed and created the world’s first production scale SF-SMB in 2014. Furthermore, Jope owns patent and knowledge to achieve ternary separation by modifying the design of a traditional SMB, bringing SMB technology to a new cutting edge.

Since founded, Jope continues to grow, to reach, and to expand for the provision of high quality and highly reliable products. We are devoted to engage professionals, partners, and customers across the field and regions. Together, we are here to create, to develop, and to success with our customers.

About Us

SMBSimulated

Moving Bed

SFESupercritical

Fluid Extraction

SF-SMBSupercritical Fluid Simulated Moving

Bed

Prep-HPLCPreparative High

Performance Liquid Chromatography

Prep-SFCPreparative

Supercritical Fluid Chromatography

Our Products

Simulated Moving Bed (SMB) is an advanced chromatography that is highly efficient in separating binary mixtures. Characterized by its continuous feeding and countercurrent flow of solid and mobile phases, SMB allows significantly higher yield and purity compare to a batch chromatography.

For information on how SMB works, please visit our website: www.jope-smb.com

Batch HPLC SMB

Characters• Suitable for multicomponent• Batch feeding

• Best for binary separation • Available for complex mixtures with special design • Easy to scale up • Continuous feeding

Solvent Consumption High Save 90%

Purity > 85% > 99%

Recovery > 70% > 99%

Productivity of Adsorbent

0.01 ~ 0.1kg/kg-day

1.0 ~ 10kg/kg-day

Advantages of SMB

High pressure unitOur systems can operate under high pressure, up to 200 bar.

Centralized /Rotary valveReduces the number of valves needed.

Patent one-step ternary separation designSaving your time and cost with a simplified process.

SMBDesign

Customized Design – Your Needs SatisfiedJope offers customized SMB based on your target, production limitation, and productivity requirement. Our unique SMB are reliable, robust, and competitive in value with excellent qualities and services that you can trust.

SMB Design of Jope

Supercritical fluid Technology – A Greener SolutionJope is the first in the world to apply CO2 as a desorbent in full scale SMB. CO2 can be fully recycled to reduce desorbent cost and yield concentrated products. As it leaves no trace of residue, supercritical CO2 is recognized as a cleaner and greener option for natural products and pharmaceutical industries.

* Available in SF-SMB, using supercritical CO2 as desorbent ** Applicable in SF-SMB only

Our Standardized Product

Pilot ScaleSMB

Production Scale SMB*

Number of Columns 8 -24 6 or 8*

Column Dimensions

25-50 mm ID 80 mm IDX X

250 mm L 450 mm L

Number of Pumps 5 2

Max operating pressure 2.0 MPa 20MPa

Flow rate 6L/hr 100L/hr

CO2 Flow Rate** - - 50kg/hr

Operating Temperature** - - 60 ºC

Pharmaceutical and API industryWith SF-SMBIsolation of β-Carotene from Paprika extract

Isolation of Schisandrin B and Schisanrol A from seed oil of Schisandra chinensis

Isolation of Tanshinone IIA from medical herb extract

Isolation of Magnolin from medical herb extract

Isolation of Resveratrol from medical herb extract

Isomer separation of Clomiphene

Separation of Sesamin and Sesamolin

With SMBChiral separation of Bisoprolol

Chiral separation of Citalopram

Chiral separation of Gossypol

Isolation of Doxorubicin from fermented liquor

Molecular weight fractionation for peptide

Separation of Astaxanthin from algal oil

Separation of Echinacoside from Cistanche deserticola extract

Separation of EPA-EE from fish oil

Separation of Flavone from bamboo leaves

Purification of astaxanthin from algae oil

Astaxanthin

Crude algae oil

SMBApplications

Food IndustrySeparation of oligosaccharides and polysaccharides

Separation of trehalose and glucose

Separation of xylose and glucose

Petroleum and Biorefinery IndustriesDesalting for bagasse hydrolyzate

Desalting for crude glycerin from biodiesel production

Separation of cyclohexanol and cyclohexanone

Separation of DMAC and HMF

Separation of propane diol and butane diol

Separation of succinic acid and acetic acid from fermented liquor

Purification of fermented drug

Purified drug

Feed

喬璞科技有限公司 Jope Technology Co., Ltd

Tel: +886-7-616 0610 e-mail: jope-smb@jope-smb.com

Fax: +886-7-616 0622 Website: http://www.jope-smb.com

Address: 82443高雄市燕巢區安林三街31號

No. 31, Anlin 3rd St., Yanchao Dist., Kaohsiung City 82443, Taiwan