Our babies: Insulin and Diabetes

By: Jeff Bangs, Ashley Kealey, and Melanie

Busch

Insulin

September 24, 2010

Ashley Kealey, Jeff Bangs, Melanie Busch

Baby Insulin

• Was born being composed of 2 peptide chains– Chains are linked by 2 disulfide bonds

• Made up of an A chain that has 21 amino acids– The A chain is also made up of 2 alpha helices

– Also 3 disulphide bonds

• Chain B is made up of 30 amino acids– 1 alpha helix

– 2 disulphide bonds

– 2 beta turns

• Amino Acid sequence varies

Family Tree

Protein

Enzymes

Insulin

Actin

*There are many

other members of

the protein family

Functions of Insulin’s family

• Builds and repairs body tissues

• Essential body processes ( water

balancing, nutrient transport, and

muscle contractions) require protein

• Source of energy

Insulin’s home

The

pancreas

creates

and

secretes

Insulin

Insulin’s helpful actions

• Regulates energy

• Regulates glucose

• Causes cells in the liver, muscle, and fat

tissues to take up glucose from the blood

and stores it as glycogen in liver and

muscle

Elements that make up Insulin

• Carbon

• Hydrogen

• Nitrogen

• Oxygen

• Sulfur

All about diabetes

http://www.youtube.com/watch?v=MHlWM8_iqfA

Diabetes

September 24, 2010

Ashley Kealey, Jeff Bangs, and Melanie Busch

Type One Diabetes

• The body doesn’t produce insulin• Only 5-10% of people with diabetes have this

form• Usually diagnosed in children and young adults• Insulin is a hormone that is needed to convert

sugar (glucose), starches, and other food into energy needed for daily life

Symptoms of Type One

• Frequent urination

• Unusual thirst

• Extreme hunger

• No more baby fat- weight loss

• Irritation and sleepiness

Type Two Diabetes

• Most common form of diabetes

• The body doesn’t produce enough insulin, or the cells ignore insulin

– Insulin is necessary for the body to be able to use glucose for energy

Symptoms of Type Two

• Any of the type 1 symptoms

• Frequent infections

• Blurred vision

• Cuts/bruises that are slow to heal

• Tingling/numbness in the hands/feet

• Recurring skin, gum, or bladder infections

Gestational Diabetes

• During pregnancy (usually around 28 weeks) many women are diagnosed

• Doesn’t mean you have/ will have diabetes around birth

• Watch blood glucose levels (blood sugar)

• High blood sugar

– Too much insulin

Why we would be great parents

• We would be energetic parents because Insulin helps us burn glucose so that we can take care of him

• We would take care of Diabetes no matter which type it is– By eating healthy and exercising

• We would show the same love and helping that our kids show for us

Love,

Your Parents

Sources of information

• "American Diabetes Association." American Diabetes Association Home Page - American Diabetes Association. Web. 03 Oct. 2010. http://www.diabetes.org/

• Bowen, R. "Insulin Structure." Arbl.cvmbs.colostate.edu. 30 June 1999. Web. 03 Oct. 2010. http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/pancreas/insulin_struct.html

• "Answers.com - How Many Elements in Insulin." WikiAnswers - The Q&A Wiki. Web. 03 Oct. 2010. <http://wiki.answers.com/Q/How_many_elements_in_insulin>.

• “INSULIN." Biology @ Davidson. Web. 03 Oct. 2010. <http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2005/Dresser/YFPright.html>.

• Lloyd, Emma. "Functions of Protein in the Human Body." Find Health, Education, Science & Technology Articles, Reviews, How-To and Tech Tips At Bright Hub - Apply To Be A Writer Today! 4 Oct. 2009. Web. 03 Oct. 2010. <http://www.brighthub.com/science/medical/articles/6050.aspx>.