Editorials How Symptomatic Should a Hypertrophic Obstructive Cardiomyopathy Patient Be to Consider Alcohol Septal Ablation? Brandon M. Jones, Amar Krishnaswamy, Nicholas G. Smedira, Milind Y. Desai, E. Murat Tuzcu, and Samir R. Kapadia e006292. DOI: 10.1161/JAHA.117.006292.

Venous Thromboembolism Risk With Antidepressants: Driven by Disease or Drugs? Brian R. Branchford e006293. DOI: 10.1161/JAHA.117.006293.

Myocardial Metabolism Under Control of a Cytokine Receptor Gustavo Ramos and Stefan Frantz e006291. DOI: 10.1161/JAHA.117.006291.

Merits of Invasive Strategy in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome Hani Jneid e005773. DOI: 10.1161/JAHA.117.005773.

Original Research Arrhythmia and Electrophysiology

Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters Emily A. Fletcher, Carolyn S. Lacey, Melenie Aaron, Mark Kolasa, Andrew Occiano, and Sachin A. Shah e004448. DOI: 10.1161/JAHA.116.004448.

Normalization of Testosterone Levels After Testosterone Replacement Therapy Is Associated With Decreased Incidence of Atrial Fibrillation Rishi Sharma, Olurinde A. Oni, Kamal Gupta, Mukut Sharma, Ram Sharma, Vikas Singh, Deepak Parashara, Surineni Kamalakar, Buddhadeb Dawn, Guoqing Chen, John A. Ambrose, and Rajat S. Barua e004880. DOI: 10.1161/JAHA.116.004880.

Survival in Women Versus Men Following Implantation of Pacemakers, Defibrillators, and Cardiac Resynchronization Therapy Devices in a Large, Nationwide Cohort Niraj Varma, Suneet Mittal, Julie B. Prillinger, Jeff Snell, Nirav Dalal, and Jonathan P. Piccini e005031. DOI: 10.1161/JAHA.116.005031.

Alogliptin, a Dipeptidyl Peptidase-4 Inhibitor, Alleviates Atrial Remodeling and Improves Mitochondrial Function and Biogenesis in Diabetic Rabbits Xiaowei Zhang, Zhiwei Zhang, Yungang Zhao, Ning Jiang, Jiuchun Qiu, Yajuan Yang, Jian Li, Xue Liang, Xinghua Wang, Gary Tse, Guangping Li, and Tong Liu e005945. DOI: 10.1161/JAHA.117.005945.

Outcome of Alcohol Septal Ablation in Mildly Symptomatic Patients With Hypertrophic Obstructive Cardiomyopathy: A Long-Term Follow-Up Study Based on the Euro-Alcohol Septal Ablation Registry Josef Veselka, Lothar Faber, Max Liebregts, Robert Cooper, Jaroslav Januska, Jan Krejci, Thomas Bartel, Maciej Dabrowski, Peter Riis Hansen, Vibeke Marie Almaas, Hubert Seggewiss, Dieter Horstkotte, Radka Adlova, Henning Bundgaard, Jurriën ten Berg, Rodney Hilton Stables, and Morten Kvistholm Jensen e005735. DOI: 10.1161/JAHA.117.005735.

JAHA: Journal of the American Heart AssociationVolume 6, Issue 5

May 2017

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Synergistic Effect of Dofetilide and Mexiletine on Prevention of Atrial Fibrillation Guizhi Liu, Xiaolin Xue, Chuanyu Gao, Jiaqi Huang, Datun Qi, Yanzhou Zhang, Jian-Zeng Dong, Chang-Sheng Ma, and Gan-Xin Yan e005482. DOI: 10.1161/JAHA.117.005482.

Cardiovascular Surgery Weekday and Survival After Cardiac Surgery—A Swedish Nationwide Cohort Study in 106 473 Patients Magnus Dalén, Gustaf Edgren, Torbjörn Ivert, Martin J. Holzmann, and Ulrik Sartipy e005908. DOI: 10.1161/JAHA.117.005908.

Quantitative Value of Aldosterone-Renin Ratio for Detection of Aldosterone-Producing Adenoma: The Aldosterone-Renin Ratio for Primary Aldosteronism (AQUARR) Study Giuseppe Maiolino, Giacomo Rossitto, Valeria Bisogni, Maurizio Cesari, Teresa Maria Seccia, Mario Plebani, Gian Paolo Rossi , for the PAPY Study Investigators e005574. DOI: 10.1161/JAHA.117.005574.

Congenital Heart Disease Hepatic Fibrosis Is Universal Following Fontan Operation, and Severity is Associated With Time From Surgery: A Liver Biopsy and Hemodynamic Study David J. Goldberg, Lea F. Surrey, Andrew C. Glatz, Kathryn Dodds, Michael L. O’Byrne, Henry C. Lin, Mark Fogel, Jonathan J. Rome, Elizabeth B. Rand, Pierre Russo, and Jack Rychik e004809. DOI: 10.1161/JAHA.116.004809.

Coronary Heart Disease Bilirubin Decreases Macrophage Cholesterol Efflux and ATP -Binding Cassette Transporter A1 Protein Expression Dongdong Wang, Anela Tosevska, Elke H. Heiß, Angela Ladurner, Christine Mölzer, Marlies Wallner, Andrew Bulmer, Karl-Heinz Wagner, Verena M. Dirsch, and Atanas G. Atanasov e005520. DOI: 10.1161/JAHA.117.005520.

Randomized Trial Comparing the Effects of Ticagrelor Versus Clopidogrel on Myocardial Perfusion in Patients With Coronary Artery Disease Matthieu Pelletier-Galarneau, Chad R. R. N. Hunter, Kathryn J. Ascah, Rob S. B. Beanlands, Girish Dwivedi, Robert A. deKemp, Benjamin J. W. Chow, and Terrence D. Ruddy e005894. DOI: 10.1161/JAHA.117.005894.

Intracoronary Administration of Allogeneic Adipose Tissue–Derived Mesenchymal Stem Cells Improves Myocardial Perfusion But Not Left Ventricle Function, in a Translational Model of Acute Myocardial Infarction Joaquim Bobi, Nüria Solanes, Rodrigo Fernández-Jiménez, Carlos Galán-Arriola, Ana Paula Dantas, Leticia Fernández-Friera, Carolina Gálvez-Montón, Elisabet Rigol-Monzó, Jaume Agüero, José Ramírez, Mercè Roqué, Antoni Bayés-Genís, Javier Sánchez-González, Ana García-Álvarez, Manel Sabaté, Santiago Roura, Borja Ibáñez, and Montserrat Rigol e005771. DOI: 10.1161/JAHA.117.005771.

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST-Segment Elevation Myocardial Infarction Sujay Chandran, Johnathan Watkins, Amina Abdul-Aziz, Manar Shafat, Patrick A. Calvert, Kristian M. Bowles, Marcus D. Flather, Stuart A. Rushworth, and Alisdair D. Ryding e005868. DOI: 10.1161/JAHA.117.005868.

Cigarette Smoking-Associated Alterations in Serotonin/Adrenalin Signaling Pathways of Platelets Curtis Lee Lowery, III, Clay Elliott, Anthonya Cooper, Coedy Hadden, Roberto N. Sonon, Parastoo Azadi, D. Keith Williams, James D. Marsh, Donna S. Woulfe, and Fusun Kilic e005465. DOI: 10.1161/JAHA.116.005465.

Epidemiology Temporal Trends in Incidence, Prevalence, and Mortality of Atrial Fibrillation in Primary Care Deirdre A. Lane, Flemming Skjøth, Gregory Y. H. Lip, Torben B. Larsen, and Dipak Kotecha e005155. DOI: 10.1161/JAHA.116.005155.

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Relations of Liver Fat With Prevalent and Incident Atrial Fibrillation in the Framingham Heart Study Michelle T. Long, Xiaoyan Yin, Martin G. Larson, Patrick T. Ellinor, Steven A. Lubitz, David D. McManus, Jared W. Magnani, Laila Staerk, Darae Ko, Robert H. Helm, Udo Hoffmann, Raymond T. Chung, and Emelia J. Benjamin e005227. DOI: 10.1161/JAHA.116.005227.

Million Hearts: Description of the National Surveillance and Modeling Methodology Used to Monitor the Number of Cardiovascular Events Prevented During 2012–2016 Matthew D. Ritchey, Fleetwood Loustalot, Hilary K. Wall, Claudia A. Steiner, Cathleen Gillespie, Mary G. George, and Janet S. Wright e006021. DOI: 10.1161/JAHA.117.006021.

Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study Corey A. Kalbaugh, Anna Kucharska-Newton, Lisa Wruck, Jennifer L. Lund, Elizabeth Selvin, Kunihiro Matsushita, Lindsay G. S. Bengtson, Gerardo Heiss, and Laura Loehr e003796. DOI: 10.1161/JAHA.116.003796.

Circulating Levels of Proprotein Convertase Subtilisin/Kexin Type 9 and Arterial Stiffness in a Large Population Sample: Data From the Brisighella Heart Study Massimiliano Ruscica, Nicola Ferri, Federica Fogacci, Martina Rosticci, Margherita Botta, Silvia Marchiano, Paolo Magni, Sergio D’Addato, Marina Giovannini, Claudio Borghi, Arrigo F. G. Cicero , for the Brisighella Heart Study Group e005764. DOI: 10.1161/JAHA.117.005764.

Comparison of Expert Adjudicated Coronary Heart Disease and Cardiovascular Disease Mortality With the National Death Index: Results From the RE asons for Geographic And Racial Differences in Stroke ( REGARDS ) Study Olusola Tope Olubowale, Monika M. Safford, Todd M. Brown, Raegan W. Durant, Virginia J. Howard, Christopher Gamboa, Stephen P. Glasser, J. David Rhodes, and Emily B. Levitan e004966. DOI: 10.1161/JAHA.116.004966.

Long-Term Effects of Unprovoked Venous Thromboembolism on Mortality and Major Cardiovascular Events Wei-Ting Chang, Chia-Li Chang, Chung-Han Ho, Chon-Seng Hong, Jhi-Joung Wang, and Zhih-Cherng Chen e005466. DOI: 10.1161/JAHA.117.005466.

Lifestyle and Risk of Screening-Detected Abdominal Aortic Aneurysm in Men Otto Stackelberg, Alicja Wolk, Ken Eliasson, Anders Hellberg, Adam Bersztel, Susanna C. Larsson, Nicola Orsini, Anders Wanhainen, and Martin Björck e004725. DOI: 10.1161/JAHA.116.004725.

American College of Cardiology/American Heart Association ( ACC / AHA ) Class I Guidelines for the Treatment of Cholesterol to Reduce Atherosclerotic Cardiovascular Risk: Implications for US Hispanics/Latinos Based on Findings From the Hispanic Community Health Study/Study of Latinos ( HCHS / SOL ) Waqas T. Qureshi, Robert C. Kaplan, Katrina Swett, Gregory Burke, Martha Daviglus, Molly Jung, Gregory A. Talavera, Diana A. Chirinos, Samantha A. Reina, Sonia Davis, and Carlos J. Rodriguez e005045. DOI: 10.1161/JAHA.116.005045.

Change in Physical Activity and Sitting Time After Myocardial Infarction and Mortality Among Postmenopausal Women in the Women’s Health Initiative-Observational Study Anna M. Gorczyca, Charles B. Eaton, Michael J. LaMonte, JoAnn E. Manson, Jeanne D. Johnston, Aurelian Bidulescu, Molly E. Waring, Todd Manini, Lisa W. Martin, Marcia L. Stefanick, Ka He, and Andrea K. Chomistek e005354. DOI: 10.1161/JAHA.116.005354.

Impact of the Metabolic Syndrome on Mortality is Modified by Objective Short Sleep Duration Julio Fernandez-Mendoza, Fan He, Caitlin LaGrotte, Alexandros N. Vgontzas, Duanping Liao, and Edward O. Bixler e005479. DOI: 10.1161/JAHA.117.005479.

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Antidepressants, Depression, and Venous Thromboembolism Risk: Large Prospective Study of UK Women Lianne Parkin, Angela Balkwill, Siân Sweetland, Gillian K. Reeves, Jane Green, Valerie Beral , for the Million Women Study Collaborators e005316. DOI: 10.1161/JAHA.116.005316.

Risk Factors for Heart Failure in Patients With Chronic Kidney Disease: The CRIC (Chronic Renal Insufficiency Cohort) Study Jiang He, Michael Shlipak, Amanda Anderson, Jason A. Roy, Harold I. Feldman, Radhakrishna Reddy Kallem, Radhika Kanthety, John W. Kusek, Akinlolu Ojo, Mahboob Rahman, Ana C. Ricardo, Elsayed Z. Soliman, Myles Wolf, Xiaoming Zhang, Dominic Raj, Lee Hamm , for the CRIC (Chronic Renal Insufficiency Cohort) Investigators e005336. DOI: 10.1161/JAHA.116.005336.

Midlife and Late-Life Vascular Risk Factors and White Matter Microstructural Integrity: The Atherosclerosis Risk in Communities Neurocognitive Study Melinda C. Power, Jonathan V. Tingle, Robert I. Reid, Juebin Huang, A. Richey Sharrett, Josef Coresh, Michael Griswold, Kejal Kantarci, Clifford R. Jack, Jr , David Knopman, Rebecca F. Gottesman, and Thomas H. Mosley e005608. DOI: 10.1161/JAHA.117.005608.

Health Services and Outcomes Research Hospital Performance on Percutaneous Coronary Intervention Process and Outcomes Measures Philip W. Chui, Craig S. Parzynski, Brahmajee K. Nallamothu, Frederick A. Masoudi, Harlan M. Krumholz, and Jeptha P. Curtis e004276. DOI: 10.1161/JAHA.116.004276.

Initiation Patterns of Statins in the 2 Years After Release of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Management Guideline in a Large US Health Plan Temitope Olufade, Siting Zhou, Deborah Anzalone, David M. Kern, Ozgur Tunceli, Mark J. Cziraky, and Vincent J. Willey e005205. DOI: 10.1161/JAHA.116.005205.

Observed Cost and Variations in Short Term Cost-Effectiveness of Therapy for Ischemic Stroke in Interventional Management of Stroke ( IMS ) III Kit N. Simpson, Annie N. Simpson, Patrick D. Mauldin, Yuko Y. Palesch, Sharon D. Yeatts, Dawn Kleindorfer, Thomas A. Tomsick, Lydia D. Foster, Andrew M. Demchuk, Pooja Khatri, Michael D. Hill, Edward C. Jauch, Tudor G. Jovin, Bernard Yan, Rüdiger von Kummer, Carlos A. Molina, Mayank Goyal, Wouter J. Schonewille, Mikael Mazighi, Stefan T. Engelter, Craig Anderson, Judith Spilker, Janice Carrozzella, Karla J. Ryckborst, L. Scott Janis, and Joseph P. Broderick e004513. DOI: 10.1161/JAHA.116.004513.

Race-Sex Differences in Statin Use and Low-Density Lipoprotein Cholesterol Control Among People With Diabetes Mellitus in the Reasons for Geographic and Racial Differences in Stroke Study Christopher M. Gamboa, Lisandro D. Colantonio, Todd M. Brown, April P. Carson, and Monika M. Safford e004264. DOI: 10.1161/JAHA.116.004264.

Patients With Heart Failure Readmitted to the Original Hospital Have Better Outcomes Than Those Readmitted Elsewhere Finlay A. McAlister, Erik Youngson, and Padma Kaul e004892. DOI: 10.1161/JAHA.116.004892.

An Initial Evaluation of the Impact of Pokémon GO on Physical Activity Ying Xian, Hanzhang Xu, Haolin Xu, Li Liang, Adrian F. Hernandez, Tracy Y. Wang, and Eric D. Peterson e005341. DOI: 10.1161/JAHA.116.005341.

T-Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure Julia Ramírez, Michele Orini, Ana Mincholé, Violeta Monasterio, Iwona Cygankiewicz, Antonio Bayés de Luna, Juan Pablo Martínez, Esther Pueyo, and Pablo Laguna e005310. DOI: 10.1161/JAHA.116.005310.

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Heart Failure Post-Myocardial Infarction T-tubules Form Enlarged Branched Structures With Dysregulation of Junctophilin-2 and Bridging Integrator 1 ( BIN -1) Christian Pinali, Nadim Malik, J. Bernard Davenport, Laurence J. Allan, Lucy Murfitt, Mohammad M. Iqbal, Mark R. Boyett, Elizabeth J. Wright, Rachel Walker, Yu Zhang, Halina Dobryznski, Cathy M. Holt, and Ashraf Kitmitto e004834. DOI: 10.1161/JAHA.116.004834.

Performance of AHEAD Score in an Asian Cohort of Acute Heart Failure With Either Preserved or Reduced Left Ventricular Systolic Function Yu-Jen Chen, Shih-Hsien Sung, Hao-Min Cheng, Wei-Ming Huang, Chung-Li Wu, Chi-Jung Huang, Pai-Feng Hsu, Jong-Shiuan Yeh, Chao-Yu Guo, Wen-Chung Yu, and Chen-Huan Chen e004297. DOI: 10.1161/JAHA.116.004297.

Different Determinants of Ventilatory Inefficiency at Different Stages of Reduced Ejection Fraction Chronic Heart Failure Natural History Alessandro Mezzani, Andrea Giordano, Klara Komici, and Ugo Corrà e005278. DOI: 10.1161/JAHA.116.005278.

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress Pu Qin, Pelin Arabacilar, Roberta E. Bernard, Weike Bao, Alan R. Olzinski, Yuanjun Guo, Hind Lal, Stephen H. Eisennagel, Michael C. Platchek, Wensheng Xie, Julius del Rosario, Mohamad Nayal, Quinn Lu, Theresa Roethke, Christine G. Schnackenberg, Fe Wright, Michael P. Quaile, Wendy S. Halsey, Ashley M. Hughes, Ganesh M. Sathe, George P. Livi, Robert B. Kirkpatrick, Xiaoyan A. Qu, Deepak K. Rajpal, Maria Faelth Savitski, Marcus Bantscheff, Gerard Joberty, Giovanna Bergamini, Thomas L. Force, Gregory J. Gatto, Jr , Erding Hu, and Robert N. Willette e004453. DOI: 10.1161/JAHA.116.004453.

Associations of Acid Suppressive Therapy With Cardiac Mortality in Heart Failure Patients Akiomi Yoshihisa, Mai Takiguchi, Yuki Kanno, Akihiko Sato, Tetsuro Yokokawa, Shunsuke Miura, Satoshi Abe, Tomofumi Misaka, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, and Yasuchika Takeishi e005110. DOI: 10.1161/JAHA.116.005110.

New Role for Interleukin-13 Receptor α1 in Myocardial Homeostasis and Heart Failure Uri Amit, David Kain, Allon Wagner, Avinash Sahu, Yael Nevo-Caspi, Nir Gonen, Natali Molotski, Tal Konfino, Natalie Landa, Nili Naftali-Shani, Galia Blum, Emmanuelle Merquiol, Danielle Karo-Atar, Yariv Kanfi, Gidi Paret, Ariel Munitz, Haim Y. Cohen, Eytan Ruppin, Sridhar Hannenhalli, and Jonathan Leor e005108. DOI: 10.1161/JAHA.116.005108.

Prognostic Value of Urinary Neutrophil Gelatinase-Associated Lipocalin on the First Day of Admission for Adverse Events in Patients With Acute Decompensated Heart Failure Yasuki Nakada, Rika Kawakami, Masaru Matsui, Tomoya Ueda, Tomoya Nakano, Akihiro Takitsume, Hitoshi Nakagawa, Taku Nishida, Kenji Onoue, Tsunenari Soeda, Satoshi Okayama, Makoto Watanabe, Hiroyuki Kawata, Hiroyuki Okura, and Yoshihiko Saito e004582. DOI: 10.1161/JAHA.116.004582.

Hypertension Graded Association Between Kidney Function and Impaired Orthostatic Blood Pressure Stabilization in Older Adults Mark Canney, Matthew D. L. O’Connell, Donal J. Sexton, Neil O’Leary, Rose Anne Kenny, Mark A. Little, and Conall M. O’Seaghdha e005661. DOI: 10.1161/JAHA.117.005661.

Endogenous Hydrogen Sulfide Enhances Carotid Sinus Baroreceptor Sensitivity by Activating the Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Channel Wen Yu, Ying Liao, Yaqian Huang, Selena Y. Chen, Yan Sun, Chufan Sun, Yuming Wu, Chaoshu Tang, Junbao Du, and Hongfang Jin e004971. DOI: 10.1161/JAHA.116.004971.

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Pulse Wave Velocity Predicts Response to Renal Denervation in Isolated Systolic Hypertension Karl Fengler, Karl-Philipp Rommel, Robert Hoellriegel, Stephan Blazek, Christian Besler, Steffen Desch, Gerhard Schuler, Axel Linke, and Philipp Lurz e005879. DOI: 10.1161/JAHA.117.005879.

Imaging Ranolazine in Symptomatic Diabetic Patients Without Obstructive Coronary Artery Disease: Impact on Microvascular and Diastolic Function Nishant R. Shah, Michael K. Cheezum, Vikas Veeranna, Stephen J. Horgan, Viviany R. Taqueti, Venkatesh L. Murthy, Courtney Foster, Jon Hainer, Karla M. Daniels, Jose Rivero, Amil M. Shah, Peter H. Stone, David A. Morrow, Michael L. Steigner, Sharmila Dorbala, Ron Blankstein, and Marcelo F. Di Carli e005027. DOI: 10.1161/JAHA.116.005027.

Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats Zongyi Xie, Budbazar Enkhjargal, Cesar Reis, Lei Huang, Weifeng Wan, Jiping Tang, Yuan Cheng, and John H. Zhang e005198. DOI: 10.1161/JAHA.116.005198.

Pediatric Cardiology Force-Sensing Catheters During Pediatric Radiofrequency Ablation: The FEDERATION Study Aarti S. Dalal, Hoang H. Nguyen, Tammy Bowman, George F. Van Hare, and Jennifer N. Avari Silva e005772. DOI: 10.1161/JAHA.117.005772.

Preventive Cardiology Effects of the Mean Amplitude of Glycemic Excursions and Vascular Endothelial Dysfunction on Cardiovascular Events in Nondiabetic Patients With Coronary Artery Disease Tomonori Akasaka, Daisuke Sueta, Noriaki Tabata, Seiji Takashio, Eiichiro Yamamoto, Yasuhiro Izumiya, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Kunihiko Matsui, and Seiji Hokimoto e004841. DOI: 10.1161/JAHA.116.004841.

Association Between Self-Reported Potentially Modifiable Cardiac Risk Factors and Perceived Need to Improve Physical Health: A Population-Based Study F. Daniel Ramirez, Yue Chen, Pietro Di Santo, Trevor Simard, Pouya Motazedian, and Benjamin Hibbert e005491. DOI: 10.1161/JAHA.117.005491.

Changes in Cardiovascular Disease Risk Factors With Immediate Versus Deferred Antiretroviral Therapy Initiation Among HIV -Positive Participants in the START (Strategic Timing of Antiretroviral Treatment) Trial Jason V. Baker, Shweta Sharma, Amit C. Achhra, Jose Ignacio Bernardino, Johannes R. Bogner, Daniel Duprez, Sean Emery, Brian Gazzard, Jonathan Gordin, Greg Grandits, Andrew N. Phillips, Siegfried Schwarze, Elsayed Z. Soliman, Stephen A. Spector, Giuseppe Tambussi, Jens Lundgren , for the INSIGHT (International Network for Strategic Initiatives in Global HIV Trials) START (Strategic Timing of Antiretroviral Treatment) Study Group e004987. DOI: 10.1161/JAHA.116.004987.

Gastric Bypass Surgery Produces a Durable Reduction in Cardiovascular Disease Risk Factors and Reduces the Long-Term Risks of Congestive Heart Failure Peter N. Benotti, G. Craig Wood, David J. Carey, Vishal C. Mehra, Tooraj Mirshahi, Michelle R. Lent, Anthony T. Petrick, Christopher Still, Glenn S. Gerhard, and Annemarie G. Hirsch e005126. DOI: 10.1161/JAHA.116.005126.

Resuscitation Science Cardiopulmonary Resuscitation Training Disparities in the United States Audrey L. Blewer, Said A. Ibrahim, Marion Leary, David Dutwin, Bryan McNally, Monique L. Anderson, Laurie J. Morrison, Tom P. Aufderheide, Mohamud Daya, Ahamed H. Idris, Clifton W. Callaway, Peter J. Kudenchuk, Gary M. Vilke, and Benjamin S. Abella e006124. DOI: 10.1161/JAHA.117.006124.

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C- GRA pH : A Validated Scoring System for Early Stratification of Neurologic Outcome After Out-of-Hospital Cardiac Arrest Treated With Targeted Temperature Management Erich L. Kiehl, Alex M. Parker, Ralph M. Matar, Matthew F. Gottbrecht, Michelle C. Johansen, Mark P. Adams, Lori A. Griffiths, Steven P. Dunn, Katherine L. Bidwell, Venu Menon, Kyle B. Enfield, and Lawrence W. Gimple e003821. DOI: 10.1161/JAHA.116.003821.

Stroke Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype Allard J. Hauer, Ynte M. Ruigrok, Ale Algra, Ewoud J. van Dijk, Peter J. Koudstaal, Gert-Jan Luijckx, Paul J. Nederkoorn, Robert J. van Oostenbrugge, Marieke C. Visser, Marieke J. Wermer, L. Jaap Kappelle, Catharina J. M. Klijn , on behalf of the Dutch Parelsnoer Institute-Cerebrovascular Accident Study Group e005090. DOI: 10.1161/JAHA.116.005090.

Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study Francisco J. de Abajo, Sara Rodríguez-Martín, Antonio Rodríguez-Miguel, and Miguel J. Gil e005795. DOI: 10.1161/JAHA.117.005795.

Systolic Blood Pressure Within 24 Hours After Thrombectomy for Acute Ischemic Stroke Correlates With Outcome Eva A. Mistry, Akshitkumar M. Mistry, Mohammad Obadah Nakawah, Nicolas K. Khattar, Enzo M. Fortuny, Aurora S. Cruz, Michael T. Froehler, Rohan V. Chitale, Robert F. James, Matthew R. Fusco, and John J. Volpi e006167. DOI: 10.1161/JAHA.117.006167.

Valvular Heart Disease Long-Term Outcomes of Patients With Mediastinal Radiation–Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study Eoin Donnellan, Ahmad Masri, Douglas R. Johnston, Gosta B. Pettersson, L. Leonardo Rodriguez, Zoran B. Popovic, Eric E. Roselli, Nicholas G. Smedira, Lars G. Svensson, Brian P. Griffin, and Milind Y. Desai e005396. DOI: 10.1161/JAHA.116.005396.

Traditional Cardiovascular Risk Factors and Their Relation to Future Surgery for Valvular Heart Disease or Ascending Aortic Disease: A Case–Referent Study Johan Ljungberg, Bengt Johansson, Karl Gunnar Engström, Elin Albertsson, Paul Holmer, Margareta Norberg, Ingvar A. Bergdahl, and Stefan Söderberg e005133. DOI: 10.1161/JAHA.116.005133.

Calcification and Oxidative Modifications Are Associated With Progressive Bioprosthetic Heart Valve Dysfunction Suengwon Lee, Robert J. Levy, Abigail J. Christian, Stanley L. Hazen, Nathan E. Frick, Eric K. Lai, Juan B. Grau, Joseph E. Bavaria, and Giovanni Ferrari e005648. DOI: 10.1161/JAHA.117.005648.

Systematic Review and Meta-Analysis Risk for Incident Heart Failure: A Subject-Level Meta-Analysis From the Heart “OMics” in AGEing (HOMAGE) Study Lotte Jacobs, Ljupcho Efremov, João Pedro Ferreira, Lutgarde Thijs, Wen-Yi Yang, Zhen-Yu Zhang, Roberto Latini, Serge Masson, Nera Agabiti, Peter Sever, Christian Delles, Naveed Sattar, Javed Butler, John G. F. Cleland, Tatiana Kuznetsova, Jan A. Staessen, Faiez Zannad , on behalf of the Heart "OMics" in AGEing (HOMAGE) investigators e005231. DOI: 10.1161/JAHA.116.005231.

Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis Ting-Ting Wu, Yuan Chen, Yun Zhou, Dilare Adi, Ying-Ying Zheng, Fen Liu, Yi-Tong Ma, and Xiang Xie e004896. DOI: 10.1161/JAHA.116.004896.

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Heart Rate Recovery and Risk of Cardiovascular Events and All-Cause Mortality: A Meta-Analysis of Prospective Cohort Studies Shanhu Qiu, Xue Cai, Zilin Sun, Ling Li, Martina Zuegel, Juergen Michael Steinacker, and Uwe Schumann e005505. DOI: 10.1161/JAHA.117.005505.

Impact of Antihypertensive Treatment on Maternal and Perinatal Outcomes in Pregnancy Complicated by Chronic Hypertension: A Systematic Review and Meta-Analysis Louise M. Webster, Frances Conti-Ramsden, Paul T. Seed, Andrew J. Webb, Catherine Nelson-Piercy, and Lucy C. Chappell e005526. DOI: 10.1161/JAHA.117.005526.

Remote Ischemic Perconditioning to Reduce Reperfusion Injury During Acute ST-Segment–Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis Shelley L. McLeod, Alla Iansavichene, and Sheldon Cheskes e005522. DOI: 10.1161/JAHA.117.005522.

Long-Term Cardiovascular Risk After Radiotherapy in Women With Breast Cancer Yun-Jiu Cheng, Xiao-Ying Nie, Cheng-Cheng Ji, Xiao-Xiong Lin, Li-Juan Liu, Xu-Miao Chen, Hao Yao, and Su-Hua Wu e005633. DOI: 10.1161/JAHA.117.005633.

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Contemporary Review Therapeutic Strategies and Drug Development for Vascular Cognitive Impairment Eric E. Smith, Alicja Cieslak, Philip Barber, Jerry Chen, Yu-Wei Chen, Ida Donnini, Jodi D. Edwards, Richard Frayne, Thalia S. Field, Janka Hegedus, Victoria Hanganu, Zahinoor Ismail, Jamila Kanji, Makoto Nakajima, Raza Noor, Stefano Peca, Demetrios Sahlas, Mukul Sharma, Luciano A. Sposato, Richard H. Swartz, Charlotte Zerna, Sandra E. Black, and Vladimir Hachinski e005568. DOI: 10.1161/JAHA.117.005568.

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is published by the American Heart Association, 7272 Greenville Avenue,Journal of the American Heart AssociationThe 2017;6:; originally published May 1, 2017;J Am Heart Assoc. 

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