GutJ7ournal of the British Society of Gastroenterology which

is a registered charity

Editor: RN Allan

Review Editor: Ian Forgacs

Technical Editor: Jackie Foulds

Editorial Assistant: Michelle Dimler

EDITORIAL BOARDD AdamsM J P ArthurI S BenjaminP BlandI W BoothR ChapmanG J Dockray

C A HartC J HawkeyS G HubscherD KumarM McMahonH O'ConnorP Quirke

D RamptonP J ShorvonD SwallowD G ThompsonB J R Whittle

R G Newcombe(Statistical adviser)

EditorBritish Medical Journal

INTERNATIONAL ADVISORY BOARDB S Anand (USA) D Y Graham (USA)C Arvanitakis (Greece) J Hansky (Australia)G P van Berge Henegouwen J Heathcote (Canada)

(Netherlands) R H Hunt (Canada)G Bianchi-Porro (Italy) J R Jass (New Zealand)A L Blum (Switzerland) S-J Jiang (China)M van Blankenstein S J Konturek (Poland)

(Netherlands) S K Lam (Hong Kong)J P Delmont (France) MM Levine (USA)J Dent (Australia) J-R Malagelada (Spain)

R Modigliani (France)T Muto (Japan)G Paumgartner (Germany)D Rachmilewitz (Israel)J Rask-Madsen (Denmark)E Rene (France)A Torsoli (Italy)

948 Book reviews, Notes

Manual of Gastroenterology. 2nd ed. ByG L Eastwood, C Avunduk. (Pp 432;illustrated; £22.95.) Boston: Little, Brown,1994. ISBN 0 316 19992 3.

The arrival of a request to review a book canbe a mixed blessing. Nice, that someone hasremembered that you are still around, butnasty, that you will have to find the time toread the book, and critically. That the bookunder review turned out to be a manual was adefinite blessing, as such a book is notdesigned to be read cover to cover, but to bedipped into. We decided to use it for eightweeks and refer to it as clinical problemsarose.

This turned out to be a big mistake as thisapproach led to a well thumbed chapter onirritable bowel syndrome and constipation.Berkshire bowel has yet to be written up as aclinical syndrome, but meant we didn't get achance to read anything on abetalipopro-teinaemia. So it was back to the cover to coverapproach.The one important draw back is that the

manual is written by Americans and forAmericans and thus the abbreviations can gettedious at times. There are also some varia-tions in treatment, such as using mineral oilfor the treatment of constipation and usingGolytely to treat hepatic encephalopathy. Ifyou grit your teeth this is a draw back worthovercoming as this is an excellent manual atan excellent price.The format works well, being spiral bound

with reasonably lightweight paper but shouldstand up to being tossed into a briefcase, butwon't stand up to being used to prop up thebed head if you get gastro-oesophageal reflux.We advise a multivolume text book of gastro-enterology for the latter.

It is absolutely crammed full of informa-tion, which is easy to assimilate, concise butnot too brief, and amazingly full of commonsense. In the section on peptic ulcer and dietthe authors comment that 'some patients feeltheir treatment is inadequate unless a strictdiet is prescribed. These patients require askilful synthesis of the art and science ofmed-icine'. Obviously a manual written by doctorswho understand their patients and also listento them. There is also a section on the chang-ing expectations of doctors and patients overthe past 50 years, with respect to consulta-tions, diagnosis, and treatment. This makesinteresting and thought provoking reading, inview of the increasing number of complaintsthat are received by all doctors at present. Wethink that the next edition should include achapter on how to deal with complaints!We whole heartedly recommend this man-

ual to those in training in gastroenterology, atall levels, and it will also be an asset to anyward based library. It is written in a refresh-ingly unstuffy style and is amazingly cheap.May the next book that comes our way be asuseful.

EMMA RAYBOULDMARGARET MYSZOR

Indigestion. By H D Janowitz. (Pp 227;illustrated; £.14.95.) New York: OxfordPaperbacks, 1992. ISBN 0 19 5085 54X.

Patient information publications are centralto the treatment of chronic conditions. Thishas long been recognised in the field of dia-betes and is now increasingly acknowledgedin gastroenterology. During the past decadethere has been a proliferation of such book-lets, particularly about inflammatory bowel

disease. In more recent times leaflets havealso appeared on upper gastrointestinal disor-ders. The success of booklets published by theBritish Digestive Foundation has confirmedthe need for this type of publication.

Initial anxieties about the effect of suchinformation on patient anxiety levels andincreased consultation rates have not beenconfirmed. Indeed, it seems probable thatbetter educated patients make more informeduse of medical resources. Indeed, the wholedirection of clinical care is now towards betterinformed patients. The concept that 'doctorknows best' is no longer valid. Indeed,perhaps the patient knows best.

Against this background you would expectthat a booklet such as Indigestion to be of par-ticular value in the treatment of patients withdyspepsia and gall stones. This booklet wasspecifically prepared for an American reader-ship and has been described by Dr LesterColeman as a 'brilliant and concise treasuretrove of information'. I would have to say thatit is an excellent summary of our currentunderstanding of both gastroduodenal, bil-iary, and pancreatic disorders. For medicalstudents it provides a quick and easily readreview. I seriously doubt, however, whether alarge number of British patients would findthe text one they could understand, or indeedone they could afford. The text is well writtenand fluent. It is clearly on a par with the typeof information found in quality newspapers.Unfortunately most of my patients readtabloids rather than broadsheets so it is quiteclear that effective patient information mustbe written in precise but simple and shortsentences. Readability of patient informationis critical to its success and it does not corre-late with well constructed long sentences. Icannot believe that the average patient willgain greatly from reading this text

J F MAYBERRY

NOTES

Gut infections

The Royal College of Pathologists is holding asymposium on An Update on Gut Infectionsin London on 5 July 1995. Further detailsfrom: Scientific Meetings Officer, RCPath, 2Carlton House Terrace, London SW1Y 5AF.Tel: 0171 930 5862 ext: 24/25.

Clinical nutrition

The Leeds Course in Clinical Nutrition willbe held on 5-8 September 1995. Furtherparticulars from: Mrs Hilary L Thackray,Department of Continuing ProfessionalEducation, Continuing Education Building,Springfield Mount, Leeds LS2 9NG. Tel:0113 322 3233.

Gastroenterology and endoscopy

The 3rd Munich Postgraduate Course onGastroenterologyr and Endoscopy will be heldon 13-15 September 1995 in Munich,Germany. Further information from: TRosch MD/Bridget Fischer, Department ofInternal Medicine II, Technical University of

Munich, Klinikum rechts der Isar,Ismaninger Str 22, 81675 Miinchen,Germany. Tel: 089 4140 2263; fax: 089 41404872.

Digestive diseases

The XXIV Panamerican Congress ofDigestive Diseases and Digestive Endoscopywill be held in Belo Horizonte/MG/Brazil on13-17 November 1995. Information from:Congress LTDA, XXIV PanamericanCongress of Digestive Diseases and DigestiveEndoscopy, Av Francisco Sales, 555/10andar, 30.150-220 Belo Horizonte/MG/Brazil. Tel: 55 31 273 1121; fax: 55 31 2734770.

Laparoscopic surgery

A European Course on Laparoscopic Surgerywill be held on 21-24 November 1995.Further information from: ConferenceServices sa, Avenue de l'Observatoire, 3 bte17, B-i 180 Bruxelles, Belgium. Tel: 32 2 37516 48; fax: 32 2 375 32 99.

Pancreatic carcinoma

The European Postgraduate Gastro-SurgicalSchool is organising an international congresson management of pancreatic carcinoma inAmsterdam on 30 November to 1 December1995. Further information from: HelmaStockmann, Managing Director EuropeanPostgraduate Gastro-Surgical School, RoomG4-109.3, Academic Medical Center,Meibergdreef 9, 1105 AZ Amsterdam, theNetherlands. Tel: 31 20 5663926; fax: 31 206914858.

Endoscopy

The Chinese University of Hong Kong andthe Hong Kong Society of DigestiveEndoscopy will hold the Tenth InternationalWorkshop on Therapeutic Endoscopy on 5-7December 1995. Further information from:Professor Sydney Chung, Endoscopy Centre,The Chinese University of Hong Kong,Prince of Wales Hospital, Shatin, NT, HongKong. Tel: 852 2632 2233; fax: 852 26350075.

ABIM announcement regarding boardeligibility

The American Board of Internal Medicine isplanning to undertake a complete review of itspolicies concerning board eligibility. TheABIM anticipates that revised board eligibil-ity policies will be announced by 31December 1996.

In the interim, the rules concerning theduration and re-establishment of the boardeligible status will be suspended. All candi-dates with this status will continue to beregarded as board eligible and therefore ableto Sit for thle certifyig examinations ininternal medicine or the subspecialties.However, the board's qualifying examination,developed to re-establish board eligibility, willnot be offered.

Candidates who have questions about thispolicy should contact the American Board ofInternal Medicine, 3624 Market Street,Philadelphia, PA 19104-2675, USA.

Gut 1995; 36: 953-955

VOLUME 36: AUTHOR INDEX - MAIN HEADINGS

Key: LA= Leading Article: C=Correspondence: A =Abstract

Abbasi AM, 801 (C)Abu Farsakh NA, 675Abulafi AM, 853Acalovschi M, 473Acheson DWK, 155 (C)Ackerman Z, 718Adolf GR, 76Adrian TE, 137, 943 (C)Affriat C, 761Ainley C, 853Akkermans LMA, 755Albarran F, 171Albert MJ, 379Albillos A, 171Alderson D, 505Aldoori WH, 276Alexander D, A478Allardice JT, 853Alvarez-Mon M, 154 (C), 171Anand BS, 327Andersen LP, 354Anderson AP, 913Andreaus MC, 294Angus PW, 927Apte MV, 287Ardill JES, 534ArendsJW, 152(C)Armstrong D, 539Arvanitakis C, 637Ascherio A, 276Asquith P, 87Atherton JC, 337, 670Atkin WS, 385Atkinson P, 939Axon ATR, 346, 351, 684, 724, 801

(C)Azar C, 947 (C)

Bachwich D, 718Bacq Y, 422Badve S, 193Baecker B, 800 (C)Baecker P, 800 (C)Baeten CGMI, 152 (C)Baird AW, 395Ballardini G, 749Balsitis M, 670Banerjee AK, 314, 803 (LA)Bangash IH, 104Banks LM, 442Banks RE, 724Barclay GR, 897Barham CP, 505Baron JH, 12, 152 (C)Bartal G, 442Barthet M, 630, 761Barton R, 28Bastid C, 947 (C)Bate CM, 492Batstra MR, 39Bayerdorffer E, 268, 945 (C)Befrits R, 922Beger HG, 771Bell GD, 462, 913Bendall RP, 800 (C)Bendix U, 548Benhamou J-P, 422Benini L, 825Benjamin I, 142Bennett PN, 251Bergman L, 880Bernard J-P, 630, 761Bernard PH, 422Berthezene P, 761Bertolissi E, 50Bessell EM, 679Besser GM, 126Bettan L, 422Bhalla AK, 710Bianchi FB, 749Billesbolle P, 766Bishop AE, 411Blackshaw PE, 337Bladen JS, 913Blanshard C, 283Blijham GH, 152 (C)Blok P, 848Blomley MJK, 442Bloom S, 604Blum AL, 539Bodmer W, 81Boiocchi M, 50Bonvicini F, 375, 838Booth JCL, 314, 427Booth SN, 492Borasio E, 375Borchard F, 306Borman PC, A479

Bortoluzzi F, 50Bosma NB, 154(C)Bovo P, 294, 799 (C)Bown SG, 67Boyer N, 422Bradley A, 442Bramble MG, 180Bramhall S, A477Bramhall SR, A479Brandtzaeg P, 737, 944 (C)Bray GP, 615Brazzola P-L, 731Brentegani MT, 825Briantais MJ, 455Brighenti F, 825Brind AM, 615Britten AJ, 243Broughton M, 90Browett PJ, 382Brown CM, 649Brown D, 897Brown JL, 427Brunori MP, 294Brunt PW, 939Buchler M, 450Buchler MW, 771Buffet C, 455Buianover Y, 845Bukhave K, 511, 528Buonaccorsi GA, 67Burgess WM, 259Burnand KG, 314Burroughs A, 437Burroughs AK, 100, 654, 931Butchoun R, 675Butler P, 931

Cales P, 422Camby I, 220Camilleri M, 743, 798 (C)Campbell FC, 189Cannizzaro R, 50Carpenter S, 90Carre IJ, 809Carter DC, A479, A480Casiraghi MC, 825Cassani F, 749Castellani G, 825Cataleta M, 749Cataudella G, 294Cavallini G, 294, 799 (C)Cawkwell L, 641 (LA)Cederberg C, 539Celik AF, 581Cernigoi C, 50Chadwick CA, 864Chalmers AG, A478Chapman R, 604Chapman RWG, 148, 485 (LA)Charlton JE, 462Chen FC, 664Chen MH, 198Chijiiwa K, 121Chin J, 654Choudari CP, 483 (LA)Ciclitira Pj, 22, 703, 874Clarke AMT, 346, 351Coates M, 209Cockayne A, 670Cohen RJ, 691Colditz GA, 276Coles GA, 639 (C)Collin P, 475 (C)Collins BJ, 809Collins CE, 5 (LA)Cooke TG, 324 (LA)Cooper AJ, A477Cooper BT, 946 (C)Coovadia YM, 419Coppere H, 422Corazza GR, 375Coremans G, 577Corfield AP, 696Couckuyt H, 577Counsell CE, 475 (C)Cox MA, 946 (C)Craanen ME, 848Craig PI, 618Cremer M, 781Crowe JP, 492

Dagorn J-C, 630, 761Dagorn JC, 1 17Dalton HR, 485 (LA)Danielsson D, 887Darnton SJ, 522Darro F, 220

Davies E, 168 (LA)Davies N, 610De Ambrogio E, 375De Reggi M, 630Deery A, 303Degos F, 422Degott C, 422Dekker W, 848Delrez R, A477Dent J, 798 (C)Deviere J, 781Devlin HB, 462Dewar M, 927D'Haens GR, 715Dhillon AP, 564Di Francesco V, 294, 799 (C)Dias JA, 553Dickson ER, 935Didier Grange J, 422Dirschedl P, 268Ditschuneit H, 450Dixon MF, 346, 351, 684, 724Dobrocky P, 251Dominguez-Mufioz JE, 450Domschke S, 800 (C)Domschke W, 800 (C)Donnelly TC, 581Dorman A, 303Dowling F, 679Dowling RH, 126Dragosics B, 831Du GG, 198Ducreux M, 455Duncan JR, 475 (C)Dunn J, A477Durantez A, 171Dwarakanath AD, 93, 570Dykhuizen RS, 939

Ebert M, 771Ekre H-PT, 341Ekundayo AA, 203El-Omar E, 534El-Omar MM, 314Elder JB, 558Elia G, 22Elias E, 433Elton R, A479Elzouki A-NY, 922Engels LGJB, 152 (C)England J, 81Epstein OE, 303Erasmus DL, 942 (C)Eriksson S, 922Erlinger S, 422Eskerod O, 511, 528Esteva F, 657

Facer P, 411Falck V, 942 (C)Falconer JS, A479, A480Farmer KCR, 251Farouk M, A479Farstad IN, 944 (C)Farthing MJG, 231, 553Fearon KCH, A479, A480Fenton-Lee D, 324 (LA)Fernandez-Corugedo A, 171Fielding G, 778Filippini M, 294, 799 (C)Filipponi C, 375Finlayson C, 193Finlayson CJ, 243Finlayson NDC, 104Finnie IA, 93Finnish Gastric Ulcer Study Group,

834Fioretta A, 825Fleming K, 604Fleming KA, 148Forbes A, 801 (C)Formela L, A478Fornasarig M, 50Foster C, 442Foster CS, 799 (C)Foster GR, 427Fourre C, 455Fraser R, 539, 798 (C)Friemann J, 813Friess H, 771Frisoni M, 375Frulloni L, 294, 799 (C)Fujii H, 788 _Fujimura Y, 944 (C)Fujita M, 788Fukuma T, 299Funnell I, A479

Gaglia P, 385Galassini R, 427Galloway SW, A478Gane J, 243Gardiner KR, 897Gasbarrini G, 375, 838Gasparaitis AE, 715Gasslander T, 137, 943 (C)Gatto MRA, 838Gazzard BG, 283Gearing AJH, 724Gevers AM, 577Geypens BJ, 183Gharib B, 630Ghironzi G, 838Ghoos YF, 183Giaffer MH, 60Gibson P, 857Gilat T, 845Gilissen K, 691Gilmore IT, 437Giovannucci EL, 276Giulianelli G, 838Go MF, 155 (C)Goldin RD, 427Gonzalez FJ, 259Gonzalez-Ruiz A, 800 (C)Goodlad RA, 203, 943 (C)Gorchein A, 67Gormsen MH, 834Goss B, 927Gotlev DC, 505Gottrand F, 155 (C)Graf W, 907Graham DY, 155 (C), 327Grassi M, 838Gray MR, 522Greaves JL, 337Greenslade L, 654Griffith JP, 684Gummett PA, 12Gunn A, 391

Haber PS, 287Haffajee Z, 691Hagel J, 800 (C)Haggett PJ, 407Haidar A, 724Hall P de la M, 259Hall PA, 391Hallak A, 845Halliday MI, 897Hallstrom 0, 239Hamilton-Miller JMT, 931Hanauer SB, 715Haner M, 731Hansen R, 766Harada K, 45Harding LK, 274, 585Harms E, 703Harris AW, 152 (C)Harris JD, A477Harrison R, 792Hart AR, 590Hart CA, 570Harvey CB, 28Hastings A, 391Hatakeyama K, 788Hatfield ARW, 67, 618Hawkey CJ, 337, 670Hayes PC, 104, 806 (LA)Hazell SL, 198Healey CJ, 148Heath D, A478Heathcote J, 318Heaton KW, 825Hectors MPC, 17Heindorff H, 766Hemingway IK, 724Hendrix TR, 945 (C)Hendrv H, 864Hentschel E, 831Hepworth-Jones B, 492Herawi M, 813Herrington MK, 137Herrlich P, 76Hewitt D, 864Hevworth MF, 154 (C)Hiele M, 577Hiele MI, 183Hillingso J, 528Hinder RA, 137Hirota I, 121Hirschl AM, 831

Hobbs KEF, 161 (LA)Hobsley M, 152 (C)Hodgson HJF, 168 (LA)Hodgson SV, 385

953

Volume 36: Author index - Main headings

Hofmann AF, 935Holcombe C, 9 (LA)Holdsworth CD, 60Holdsworth PJ, 902Holloway RH, 499Holm K, 239Holmes EC, 148Hopkins A, 437, 462Hopman WPM, 17Hoppeler Th, 731Horowitz M, 798 (C)Hu PJ, 198Huang BJ, 198Hubscher S, 433, 792Hughes LA, 28Hultcrantz R, 922Hungin APS, 180Hunt JA, 522Hunt RH, 800 (C)Hunter JO, 942 (C)Hurst HC, A477Husband D, 87Hussain W, 792Hussaini SH, 126Hutchinson R, 274, 585Huupponen T, 239

Ibbotson JP, 1 (LA)Ibbotson SH, 724Idstrom J-P, 539Ikeda H, 45Ikeda T, 299Imrie CW, A478Insam B, 419Iovanna JL, 117Iqbal TH, 946 (C)Irlam RW, 522Ishida 0, 45

Jaakkola M, 1 17Jackson LD, 459Jackson P, 346, 351Jain S, 146Jansen JBMJ, 17, 39, 176Jarnerot G, 639 (C), 640 (C), 887Jaskiewicz K, 544Jass JR, 153 (C), 382Jazrawi RP, 330Jeevaratnam P, 382Jenkins AP, 314, 943 (C)Jenkins D, 437, 679Jenkins SA, 100, 610Jewell DP, 407Johnson CD, A477Johnston BT, 481 (LA), 809Johnston D, 684, 902Jones AF, 87Jones AL, 104Jones SC, 724Jorgensen RA, 935Jorgensen T, 819Joseph AEA, 243

Kakkar AK, A479Kanda T, 788Kane JA, 146Kane KF, 255Kane SP, 146Kang JY, 664Karanjia ND, 133Karim QN, 12Karlbom U, 907Karmeli F, 718Karttunen R, 341Karttunen T, 341Katsinelos P, 581Keeling PWN, 492Keely SJ, 395Kelleher D, 34Kennedy C, 126Keusch GT, 155 (C)Khalil B, 675Khan MI, 581Khulusi S, 193Kihara T, 944 (C)Kingsnorth AN, A478Kino I,516Kirk GE, 670Kiss R, 220Kitayama Y, 516Kivilaakso E, 834Klee GG, 743Kluin-Nelemans JC, 311Kluin PhM, 311Kobayashi F, 299Komoda T, 299Konikoff FM, 845Koppeschaar HPF, 755Korsten MA, 287Koskinas J, 599Krige JEJ, A479Kromer W, 813

Kruczynski A, 220Kubben FJGM, 152 (C)Kumar D, 274, 585Kumar U, 427Kvale D, 737Kynaston H, 610

Lafiandra D, 375Lamers CBHW, 39, 176, 311Lanas AI, 657Langhans J, 771Langman MJS, 255, 488Lanzon-Miller S, 28Larvin M, A478Lastovica AJ, 544Laugier R, A477Laurent-Puig P, 455Ledeboer M, 39Lee CY, 203Lee JCW, 411Lehmann I, 548Lemoine NR, A477, A479Lenzen R, 306Lenzi M, 749Levi J, 330Lew GM, 327Lewin J, 564Lewis KO, 946 (C)Lewis SA, 481 (LA)Lewis WG, 902Li S, 442Li YY, 198Lieverse RJ, 176Ligard Pedersen S, 766Lilova A, 630Lindberg E, 887Lindor KD, 935Ljungh, 401Ldfberg R, 880Logan RFA, 153 (C)Logan RPH, 12Long A, 34Lord BI, 864Loriot MA, 422Losowsky MS, 317Loudon MA, 189Louw JA, 544Love AHG, 481 (LA)Lowes JR, 1 (LA)Lubin R, 455Lubke H, 306Lucke W, 544Lundin KEA, 874Lux G, 800 (C)Lynch DAF, 346, 351

McCaughan GW, 287McCloy RF, 462McColl KEL, 534McConkey C, A477McCormick PA, 100, 654McDevitt J, 34MacDonald TT, 341McFarlane XA, 710McGregor JR, 475 (C)Macintyre IMC, 475 (C)McIntyre N, 100, 654, 931Mackay EH, 696McKie A, A477McKinnon RA, 259McMahon MJ, A478, 684McManus ME, 259McMaster P, 433McPeake J, 644 (LA)MacRobert AJ, 67Maes BD, 183Mahalanabis D, 379Maingay JP, A479, A480Maki M, 239Makino I, 121Makumbi F, 419Malagelada J-R, 363Malesci A, 622Malfertheiner P, 450Maloney A, 679Man W, 442Mannes GA, 268Manotti P, 749Mansfield JC, 60Manzano L, 154 (C), 171Mapstone NP, 346, 351Marcellin P, 422Marcori M, 294Mariani A, 622Markesich DC, 327Marks CG, 90Marks IN, 544Marrero JM, 330Martin B, 433Martin DF, 446Martin I, 684Martinez J, 220Martinoli S, 731

Marumo F, 299Mary J-L, 731Masclee AAM, 39, 176Masoomi AM, 243Mathers JC, 391Maxton DG, 446Maxwell JD, 243, 330Maxwell RJ, 897May B, 813Mayberry JF, 590, 696Mayer D, 450Mayo K, 838Mazure G, 564Mearin F, 363Meera Khan P, 731M6graud F, 838Melbourne Liver Group, 927Mendall MA, 193, 330Mertz-Nielsen A, 511, 528Mezzi G, 622Michel R, 630Middleton SJ, 942 (C)Millard S, 55Miller AS, 902Mills A, 274, 505Mills SJ, 391Milne L, 897Milton JD, 570Minniti G, 825Misiewicz JJ, 12Mitchell HM, 198Mitsuyama K, 45Molineaux N, 330Montesi G, 294Moola SAH, 419Moore NR, 407Moran A, 87Morgan GP, 153 (C)Morgan LM, 710Morrison L, 346Mortensen NJ, 407Moshkowitz M, 845Moss S, 942 (C)Mossi S, A477Mothes T, 548Mountford RA, 492Mourad FH, 553Mukaida H, 137Mulder JWR, 76Muller A, 731Muller AF, 165 (LA), 679Muller Hj, 731Munck LK, 215Muratori L, 749Murphy A, 34Murphy GM, 126Murray-Lyon IM, 437Mutimer D, 433, 792Myers M, 442

Nakamura S, 516Nakano K, 121Nathanson L, 778Nelufer J, 874Nemeth J, 522Neoptolemos J, A477Neoptolemos JP, A479Nerin J, 657Neuberger J, 433, 792Nicholson DA, 442Nielsen H, 354Nilsson S, 907Nishiyama T, 45Noach LA, 154 (C)Noguchi 0, 299Nordback I, 117Norgaard A, 354Northfield TC, 193, 330Northover JMA, 385Noshiro H, 121Notarianni LJ, 251Notghi A, 274, 585Nouri-Aria KT, 599Nov R, 857Nugent KP, 251

O'Brien S, 618O'Callaghan H, 180Ochsenkuhn T, 268O'Donnell LJD, 553O'Donoghue DP, 358, 395O'Dwyer PJ, 475 (C)Offerhaus GJ, 801 (C)Offerhaus GJA, 76, 848Ogutu E, 553Oliver S, 251Oliver SE, 153 (C)Ono T, 788Oosting J, 154 (C)Oriishi T, 891O'Riordan DK, 303O'Riordan MG, A479Owen G, 864

Pahlman L, 907Palmer KR, 483 (LA)Pals ST, 76, 801 (C)Panos MZ, 488Papo M, 363Pasteels J-L, 220Pasternack A, 475 (C)Patchett SE, 358Patel P, 193Paumgartner G, 268Peeters-Haesevoets A, 152 (C)Peeters TL, 755Peled Y, 845Pellegrini N, 825Pelletier G, 455Penman I, 534Pereira SP, 126Perkins AC, 337Perry T, 696Pfannschmidt C, 548Pfeiffer A, 813Phillips AD, 231, 321 (LA), 369Phillips RKS, 251, 918Piasecki C, 654Pikkarainen P, 834Pirola RC, 287Playford RJ, 943 (C)Plester CE, A479Podolsky DK, 718Polak JM, 411Polak MM, 76Poletti M, 50Porceddu E, 375Poremba C, 703Porrini M, 825Portal I, A477Portmann B, 142Portmann BC, 599, 615Posthuma EFM, 311Potten CS, 864Pounder RE, 564Pouteau M, 422Pretolani S, 838Probert CSJ, 696Przemioslo R, 22Przemioslo RT, 874

Quine MA, 462Quirke P, 346, 351, 641 (LA)

Rachmilewitz D, 718, 942 (C)Ramage JK, 142Rampton DS, 5 (LA), 411Rask-Madsen J, 511, 528Rauws EAJ, 154 (C)Ravdin JL, 800 (C)Ravichandran D, A477Read NW, 581Reber HA, 133Rees WDW, 649Reeves DE, 710Regula J, 67Reske SN, 771Reunala T, 475 (C)Reynolds PD, 942 (C)Rhodes J, 639 (C)Rhodes JM, 93, 570Rhodes M, 778Riach E, 324 (LA)Richardson PDI, 492Rickaert F, 781Rigo L, 294Rimm EB, 276Robberecht P, 781Roberts-Thomson SJ, 259Robertson DAF, 710Robinson PJ, A478Roediger WEW, 55Rolf TM, 154 (C)Ronaasen V, 209Rosella 0, 857Rosenbusch G, 17Rosenstock SJ, 819Ross JA, A479, A480Rossi SS, 935Roweily E, 675Rowlands BJ, 897Ruddell WSJ, 475 (C)Ruge M, 813Ruppin H, 800 (C)Russell RI, 334Rutgeerts P, 577Rutgeerts PJ, 183

Sagar PM, 153 (C), 902Sahel J, 630, 761Sainz R, 657Sakagishi Y, 299Sakai Y, 788Sakamoto S, 299Salim AF, 231Sams VR, 28

954

Volume 36: Author index - Main headings

Samsom M, 755Sandle LN, 649Santo M, 845Sarner M, 28Sasaki E, 45, 891Sata M, 891Sathar MA, 419Sato C, 299Saunders BP, 913Savidge TC, 321 (LA), 369Sayegh M, 558Scates DK, 918Schatz H, 813Schatzl M, 813Schiefer B, 450Schiller KFR, 796Schoeman MN, 499Schofield PF, 152 (C)Schumacher U, 209Schurmann GM, 411Schutte B, 152 (C)Schutze K, 831Schwartz MP, 154 (C)Schwegler U, 813Scott BB, 468Scott RJ, 731Segal I, 691Sembenini C, 825Semhoun-Decloux S, 455Seppala K, 834Sewell RB, 927Sharma R, 209Shaw J, 433Shearman JD, 407Sheils 0, 34Shen W, 401Shepherd NA, 391Shoda R, 379Shorthouse M, 942 (C)Sikora K, A477Sim R, 564Simiee AE, 419Simmonds P, 148Simpson JG, 939Simpson KJ, 104, 806 (LA)Sipponen P, 834Skidmore S, 433Slater SD, 799 (C)Slee B, 649Small PK, 189Smallwood RA, 927Smith CC, 939Smith D, 189Smith DB, 148Smith NB, 585Smith P, 679Smith-Ravin J, 81

Smout AJPM, 755Sninsky CA, 640 (C)Snowdon CF, 649Sobala GM, 346Sollid LM, 874Solo Investigator Group, 492Song E, 459Soni PN, 419Soussi T, 455Sozzi M, 50Spencer GM, 67Spigelman AD, 251, 918Spiller RC, 337, 670Spycher M, 731Stack WA, 395Stal P, 922Stamler JS, 718, 942 (C)Stamp G, A477Stampfer MJ, 276Steele RJC, 803 (LA)Steinruck H, 401Steitieh M, 675Stephens S, 897Stevenson C, 488Stockbrugger RW, 152 (C)Stolk MFJ, 755Stollfuss J, 771Stolte M, 945 (C)Strohmeyer G, 306Sturrock RD, 334Sue-Ling HM, 684Sugimura H, 516Swain CP, 853Swallow DM, 28Swart GR, 110

Taha AS, 334Talbot IC, 81, 385, 801 (C)Tan K-C, 142Tanikawa K, 45, 891Tateishi H, 45Taylor BA, 93, 610Taylor L, 691Taylor MD, 492Teng CH, 664Terblanche J, A479Testolin G, 825Thomas HC, 427Thomas PS, 809Thomforde GM, 743Thompson RPH, 314, 943 (C)Thornley AL, 691Thorpe SM, 67Thurrell WP, 28Tibbs CJ, 599Tiomny E, 845

Toffoli G, 50Toghill PJ, 165 (LA), 679Tonelli E, 838Tougas G, 800 (C)Tovey FI, 154 (C)Toyonaga A, 45, 891Tozuka S, 299Travis SPL, 407Trichopoulos DV, 276Tsai HH, 570Tsuruta 0, 45Turck D, 155 (C)Tweedle DEF, 446Tysk C, 887Tytgat GNJ, 154 (C), 848

Uddin W, 142

Valentini M, 50Van de Water NS, 382van den Berg FM, 76van der Luijt R, 731van der Sluys Veer A, 311Van Eeden PJ, 942 (C)van Erpecum KJ, 755Van Helden P, 942 (C)van Hoek B, 110Van Laethem J-L, 781Van Rampelbergh J, 781van Someren N, 853Van Wynk MEC, A479vanBerge-Henegouwen GP, 755van't HofA, 691Vantini I, 825Vaona B, 294, 799 (C)VargasJA, 171VecchioM, 411Venitt S, 918Verboeket-van de Venne WPHG,

110Verdu EF, 539Veress B, 880Vertongen P, 781Viani F, 539Victor TC, 942 (C)Vilstrup H, 766Vincent P, 155 (C)Vogl R, 800 (C)von der Ohe MR, 743

Wahed MA, 379Wakefield AJ, 564Waldron B, 189Walker J, 104

Walker JL, 148Walker MM, 12Walker-Smith JA, 231, 321 (LA),

369Wallace HM, 522Walt RP, 488Wang Y, 28Ward J, A478Warren BF, 696Washington N, 337Wass JAH, 126Watanapa P, 943 (C)Watson RGP, 927Weber P, 703Wee A, 664Weldon MJ, 243Westaby D, 647 (LA)Westendorp RGJ, 311Westerterp KR, 110Whitelaw S, 385Wicks ACB, 590Widdison AL, 133Wiebecke B, 268Wielenga VJM, 76Wigmore SJ, A479, A480Wiliams GR, 255Willett WC, 276Williams CB, 385, 913Williams JG, A479Williams NS, 853Williams R, 142, 437, 599, 615, 644

(LA)Williams RCN, A479Williams SGJ, 647 (LA)Williams SP, 618Williamson MER, 902Williamson RCN, 799 (C), 943 (C)Wilson C, A478, A479Wilson JS, 287Wilson MS, 152 (C)Wilson P, 142Wing AL, 276Winter TA, 544Woolford LB, 864Wright NA, 22, 943 (C)

Yang P, 887Yardley JH, 945 (C)Yates J, 610Young G, 857

Zhou MH, 198Zimmer K-P, 703

955

Gut 1995; 36: 956-964

VOLUME 36: SUBJECT INDEX - MAIN HEADINGS

Achalasia, Impaired gastric relaxation in patients with achalasia, 363Acid, Effect of topical oesophageal acidification on human salivary and

oesophageal alkali secretion, 649Acid inhibition, Effect of Helicobacter pylori status on intragastric pH

during treatment with omeprazole, 539Acid reflux, Precipitating causes of acid reflux episodes in ambulant

patients with gastro-oesophageal reflux disease, 505Acromegaly, Effect of octreotide on fasting gall bladder emptying,

antroduodenal motility, and motilin release in acromegaly, 755Acupuncture, Relation of acupuncture and vagal gastric acid secretion:

correspondence, 800Adenine arabinoside, Adenine arabinoside 5'-monophosphate in

patients with chronic hepatitis B: comparison of the efficacy inpatients with high and low viral replication, 422

Adenomas, Variables associated with the risk of colorectal adenomas inasymptomatic patients with a family history of colorectal cancer,385

Adenosine deaminase activity, Ascitic fluid gamma interferon concen-trations and adenosine deaminase activity in tuberculous peri-tonitis, 419

Adhesion moleculesAdhesion molecule expression in primary sclerosing cholangitis and

primary biliary cirrhosis, 604Adhesion molecules in inflammatory bowel disease, 724Constitutive and cytokine induced expression of HLA molecules,

secretory component, and intercellular adhesion molecule-i ismodulated by butyrate in the colonic epithelial cell line HT-29, 737

Current concepts in metastasis: correspondence, 153Expression of adhesion molecules in human Peyer's patches: corres-

pondence, 944Increased expression of cell adhesion molecule P-selectin in active

inflammatory bowel disease, 411Serum intercellular adhesion molecule-i levels in chronic hepatitis C:

association with disease activity and response to interferon alpha,599

Soluble adhesion molecules in immune mediated liver disease: leadingarticle, 806

Adhesive properties, Expression of binding of plasminogen, thrombo-spondin, vitronectin, and fibrinogen, and adhesive properties byEscherichia coli strains isolated from patients with colonic diseases,401

AIDS, Natural history and prognosis of diarrhoea of unknown causein patients with acquired immunodeficiency syndrome (AIDS),283

Alcohol, Secretin induces a paradoxical sphincter of oddi hyperpressureeffect in alcoholic patients without pancreatic disease, A477

Alcohol consumption, Increased serum pancreatitis associated protein(PAP) concentration after longterm alcohol consumption: furtherevidence for regular subclinical pancreatic damage after heavydrinking? 117

Alkaline phosphatase, A variant alkaline phosphatase found in a case ofgastric carcinoma with super bone scan, 299

Alpha, antitrypsin, Diagnostic value of a guaiac occult blood test andfaecal a, antitrypsin, 87

Alpha, antitrypsin deficiency, Increased PiZ gene frequency for a,antitrypsin in patients with genetic haemochromatosis, 922

Amino acidsChloride dependent amino acid transport in the human small

intestine, 215Controlled trial of oligopeptide versus amino acid diet in treatment of

active Crohn's disease, 60Somatostatin prevents the postoperative increases in plasma amino

acid clearance and urea synthesis after elective cholecystectomy,766

5 Aminolaevulinic acid, Photosensitisation and photodynamic therapyof oesophageal, duodenal, and colorectal tumours using 5aminolaevulinic acid induced protoporphyrin IX, 67

5-Aminosalicylic acidAn alternative view of 5-ASA formulations: correspondence, 639New salicylates as maintenance treatment in ulcerative colitis: corres-

pondence, 640Amoebiasis, Diagnosis of invasive amoebiasis: renaissance of the

morphology era: correspondence, 800Amoxycillin, Detection of the intragastric sites at which Helicobacter

pylori evades treatment with amoxycillin and cimetidine, 670Ampullary cancer, Collagenase, stromelysin, and tissue inhibitor of

metalloproteinase expression in pancreatic and ampullary cancer,A477

Ampullary carcinoma, Photodynamic therapy for malignant tumours ofthe ampulla of Vater, 853

Anaesthesia, Prospective audit of upper gastrointestinal endoscopyin two regions of England: safety, staffing, and sedation methods,462

Anorectal physiology, Preservation of complete anal sphincteric pro-prioception in restorative proctocolectomy: the inhibitory reflexand fine control of continence need not be impaired, 902

Antacids, High pH reduces DNA damage caused by bile from patientswith familial adenomatous polyposis: antacids may attenuateduodenal polyposis, 918

Anticoagulant drugs, Acute gastrointestinal haemorrhage in patientstreated with anticoagulant drugs: leading article, 483

Antineutrophil cytoplasmic antibodies, P-ANCA in monozygotic twinswith inflammatory bowel disease, 887

Antroduodenal motility, Effect of octreotide on fasting gall bladderemptying, antroduodenal motility, and motilin release in acro-megaly, 755

APC gene, Novel germline APC gene mutation in a large familialadenomatous polyposis kindred displaying variable phenotypes,731

Artificial liver, Artificial livers - what's keeping them? leading article,168

AuditIndications, methods, and outcomes of percutaneous liver biopsy in

England and Wales: an audit by the British Society of Gastroentero-logy and the Royal College of Physicians of London, 437

Pancreatic carcinoma: an audit of treatment, survival, and quality oflife, A479

Prospective audit of upper gastrointestinal endoscopy in two regionsof England: safety, staffing, and sedation methods, 462

Australia, Low prevalence of primary biliary cirrhosis in Victoria,Australia, 927

Autoimmune gastritis, Functional defect of T cells in autoimmunegastritis, 171

Autoimmune hepatitis type 2, Liver cytosolic 1 antigen-antibodysystem in type 2 autoimmune hepatitis and hepatitis C virusinfection, 749

Autoimmune thyroid disease, Association between coeliac disease andautoimmune thyroid disease: correspondence, 475

Autoimmunity, Autoimmunity and chronic pancreatitis: correspondence,799

Azathioprine, Fatal infectious mononucleosis: a severe complication inthe treatment of Crohn's disease with azathioprine, 311

Bacterial colitis, Pathogenesis of bacterial colitis: correspondence,154

Bacterial translocation, Bacterial translocation in the rat model of lectininduced diarrhoea, 379

Barium examination, Gastroenterology in the Trent Region in 1992 anda review of changes since 1975, 468

Barrett's oesophagus, Twenty to 40 year follow up of infantile hiatalhernia, 809

BicarbonateEffect of topical oesophageal acidification on human salivary and

oesophageal alkali secretion, 649Muscarinic M, receptor inhibition reduces gastroduodenal bicarbo-

nate secretion and promotes gastric prostaglandin E2 synthesis inhealthy volunteers, 528

Bile acids, Unconjugated secondary bile acids in the serum of patientswith colorectal adenomas, 268

Bile duct obstruction, A three year follow up of self expanding metalstents in the endoscopic palliation of longterm survivors withmalignant biliary obstruction, 618

Bile duct stones, Role of biliary stenting in the management of bile ductstones in the elderly: leading article, 485

Biliary cancer, Antibodies against p53 protein in serum of patients withbenign or malignant pancreatic and biliary diseases, 455

Biliary lithiasis, Is biliary lithiasis associated with pancreatographicchanges? 761

Biliary pancreatitis, Current views on the pathophysiology of acutebiliary pancreatitis: leading article, 803

Biliary stentingRetained common bile duct stones after endoscopic sphincterotomy:

temporary and longterm treatment with biliary stenting, 446Role of biliary stenting in the management of bile duct stones in the

elderly: leading article, 485Biopsy, Indications, methods, and outcomes of percutaneous liver

biopsy in England and Wales: an audit by the British Society ofGastroenterology and the Royal College of Physicians of London,437

956

Volume 36: Subject index - Main headings

Book reviewsChen JZ, McCallum RW. Electrogastrophy - principles and applica-

tions, 802Cotton PB, Tytgat GNJ, Williams CB, editors. Annual of gastrointesti-

nal endoscopy, 156Drossman DA, editor. Functional gastrointestinal disorders, 320Eastwood GL, Avunduk C. Manual of gastroenterology, 2nd ed, 948Janowitz HD. Indigestion, 948Kamm MA, editor. Constipation, 476Morris AI, Yiannakou JY. Illustrated case histories: gastroenterology,

320Phillips RKS, Spigelman AD, Thomson JPS, editors. Familialadenomatous polyposis and other polyposis syndromes, 947

Reesink HW, editor. Hepatitis C virus. Current studies in hematologyand blood transfusion, 320

Targan SR, Shanahan F, editors. Inflammatory bowel disease. Frombench to bedside, 156

British Society of GastroenterologyPresident 1994-95, Ian Bouchier, 151Presidential review of the year's activity 1993-4, 317

ButyrateColonic epithelium is diffusely abnormal in ulcerative colitis and

colorectal cancer, 857Constitutive and cytokine induced expression of HLA molecules,

secretory component, and intercellular adhesion molecule-l ismodulated by butyrate in the colonic epithelial cell line HT-29, 737

13C-urea breath test, Effect of a test meal on the intragastric distribu-tion of urea in the "C-urea breath test for Helicobacter pylori, 337

CA 125, Increased CA 125 in a patient with tuberculous peritonitis: casereport and review of published works, 303

Canada, Gastroenterological practice in Canada, 318Cancer surveillance, Cancer surveillance in ulcerative colitis: correspon-

dence, 801Capsaicin, Effect of capsaicin and chilli on ethanol induced gastric

mucosal injury in the rat, 664Cathepsin D, Translocation ofgliadin into HLA-DR antigen containing

lysosomes in coeliac disease, 703CD44

Colorectal tumorigenesis: correspondence, 801Expression of mutant p53 protein and CD44 variant proteins in

colorectal tumorigenesis, 76Celi cycle, DNA flow cytometric evaluation of cell cycle distribution in

ulcerative colitis: a proposed method for assessing severity ofdisease, 50

Cell division, Gastrin and the growth of the gastrointestinal tract, 203Cell kinetics, Stimulation and inhibition of proliferation in the small

intestinal crypts of the mouse after in vivo administration ofgrowthfactors, 864

Cell lines, Characterisation of the influence of anti-gastrin, anti-epidermal growth factor, anti-oestradiol, and anti-luteinising hor-mone releasing hormone antibodies on the proliferation of 27 cellslines from the gastrointestinal tract, 220

Cell proliferationCell proliferation in the gastric corpus in Helicobacter pylori associated

gastritis and after gastric resection, 351Cell proliferation in Helicobacter pylori associated gastritis and the

effect of eradication therapy, 346Colonic cell proliferation in two different ethnic groups with contrasting

incidence of colon cancer: is there a difference in carcinogenesis? 691Proliferative compartment deregulation in the non-neoplastic colonic

epithelium of familial adenomatous polyposis, 391Children

Relation between gastric emptying rate and energy intake in childrencompared with adults, 183

Twenty to 40 year follow up of infantile hiatal hernia, 809Chilli, Effect of capsaicin and chilli on ethanol induced gastric mucosal

injury in the rat, 664Chinese herbs, Hepatitis induced by traditional Chinese herbs: possible

toxic components, 146Chlorides, Chloride dependent amino acid transport in the human small

intestine, 215Cholecystectomy

Laparoscopic cholecystectomy: leading article, 161Prevalence ofHelicobacter pylori in patients with gall stones before and

after cholecystectomy, 675Somatostatin prevents the postoperative increases in plasma amino

acid clearance and urea synthesis after elective cholecystectomy,766

CholecystokininEffect of cholecystokinin on lower oesophageal sphincter pressure and

transient lower oesophageal sphincter relaxations in humans, 39Effect of predigested fat on intestinal stimulation of plasma

cholecystokinin and gall bladder motility in coeliac disease, 17Satiety effects of a physiological dose of cholescystokinin in humans,

176

Cimetidine, Detection of the intragastric sites at which Helicobacterpylori evades treatment with amoxycillin and cimetidine, 670

CirrhosisEnergy expenditure and substrate metabolism in patients with

cirrhosis of the liver: effects of the pattern of food intake, 110Portal and systemic haemodynamic response to acute and chronic

administration of low and high dose isosorbide-5-mononitrate inpatients with cirrhosis, 104

Coeliac diseaseAnalysis of crypt cell proliferation in coeliac disease using MI-B1

antibody shows and increase in growth function, 22Association between coeliac disease and autoimmune thyroid disease:

correspondence, 475Effect of predigested fat on intestinal stimulation of plasma

cholecystokinin and gall bladder motility in coeliac disease, 17Histological changes in small bowel mucosa induced by gliadin

sensitive T lymphocytes can be blocked by anti-interferon gammaantibody, 874

Intestinal proliferation in coeliac disease: looking into the crypt:leading article, 321

Novel insights into human intestinal epithelial cell proliferation inhealth and disease using confocal microscopy, 369

Osteoporosis in treated adult coeliac disease, 710Seroconversion of reticulin autoantibodies predicts coeliac disease in

insulin dependent diabetes mellitus, 239Translocation of gliadin into HLA-DR antigen containing lysosomes

in coeliac disease, 703Wheat deficient in gliadins: promising tool for treatment of coeliac

disease, 375Colitis

Pathogenesis of bacterial colitis: correspondence, 154Selective inhibition of fatty acid oxidation in colonocytes by

ibuprofen: a cause of colitis? 55Colitis ulcerosa, Colitis ulcerosa complicated by malignant lymphoma:

case report and analysis of published works, 306Collagen, Microscopic colitis syndrome, 880Collagenase, Collagenase, stromelysin, and tissue inhibitor of metal-

loproteinase expression in pancreatic and ampullary cancer, A477Colon

Differential regional effects of octreotide on human gastrointestinalmotor function, 743

Immune regulation of human colonic electrolyte transport in vitro,395

Microscopic colitis syndrome, 880Colon cancer

Colonic cell proliferation in two different ethnic groups with contrast-ing incidence ofcolon cancer: is there a difference in carcinogenesis?691

NSAIDs and the chemoprevention of colon and oesophageal cancer:correspondence, 153

Colonic cell proliferationColonic cell proliferation in two different ethnic groups with contrast-

ing incidence ofcolon cancer: is there a difference in carcinogenesis?691

Markers to study human colonic cell proliferation: correspondence, 152Colonic disease, Expression of binding of plasminogen, thrombospon-

din, vitronectin, and fibrinogen, and adhesive properties byEscherichia coli strains isolated from patients with colonic diseases,401

Colonic epithelial cell line, Constitutive and cytokine induced expres-sion of HLA molecules, secretory component, and intercellularadhesion molecule- 1 is modulated by butyrate in the colonicepithelial cell line HT-29, 737

Colonic epithelium, Colonic epithelium is diffusely abnormal inulcerative colitis and colorectal cancer, 857

Colonic mucin synthesis, Colonic mucin synthesis is increased bysodium butyrate, 93

Colonic transitRelationships between defecographic findings, rectal emptying, and

colonic transit time in constipated patients, 907Reporting simplified colonic transit studies using radionuclides:

clinician friendly reports, 274Colonoscopy, First clinical results with a real time, electronic imager as

an aid to colonoscopy, 913Colorectal cancer

1,25-dihydroxyvitamin D, and retinoid X receptor expression inhuman colorectal neoplasms, 255

A new class of colorectal cancer gene: leading article, 641A screening clinic for relatives of patients with colorectal cancer in a

district general hospital, 90Analysis of Ha-ras 1 allele frequencies in hereditary non-polyposis

colorectal cancer, 382Colonic epithelium is diffusely abnormal in ulcerative colitis and

colorectal cancer, 857Colorectal cancer screening in asymptomatic populations, 590Death from malignant disease after surgery for duodenal ulcer:

correspondence, 475

957

958

Detection of c-Ki-ras mutations in faecal samples from sporadiccolorectal cancer patients, 81

Unconjugated secondary bile acids in the serum of patients withcolorectal adenomas, 268

Variables associated with the risk of colorectal adenomas in asymp-tomatic patients with a family history of colorectal cancer, 385

Colorectal tumongenesisColorectal tumorigenesis: correspondence, 801Expression of mutant p53 protein and CD44 variant proteins in

colorectal tumorigenesis, 76Common bile duct stones, Retained common bile duct stones after

endoscopic sphincterotomy: temporary and longterm treatmentwith biliary stenting, 446

Confocal microscopy, Novel insights into human intestinal epithelialcell proliferation in health and disease using confocal microscopy,369

Conjugated/unconjugated bile acid fraction, Unconjugated secondarybile acids in the serum of patients with colorectal adenomas, 268

ConstipationHereditary proctalgia fugax and constipation: report of a second

family, 581Relationships between defecographic findings, rectal emptying, and

colonic transit time in constipated patients, 907Scintigraphic measurement of ileocaecal transit in irritable bowelsyndrome and chronic idiopathic constipation, 585

Correction, 157Corticosteroid resistance, Cyclosporin in the treatment of corti-

costeroid resistant autoimmune chronic active hepatitis, 459Crohn's disease

Controlled trial of oligopeptide versus amino acid diet in treatment ofactive Crohn's disease, 60

Duration of recurrent ileitis after ileocolonic resection correlates withpresurgical extent of Crohn's disease, 715

Efficacy and safety of hydrostatic balloon dilatation of ileocolonicCrohn's strictures: a prospective longterm analysis, 577

Enhanced colonic nitric oxide generation and nitric oxide synthaseactivity in ulcerative colitis and Crohn's disease, 718

Fatal infectious mononucleosis: a severe complication in the treatmentof Crohn's disease with azathioprine, 311

Mycobacterium paratuberculosis and Crohn's disease: corespondence, 942Pelvic and perineal complications ofCrohn's disease: assessment using

magnetic resonance imaging, 407Potential role of superantigen induced activation of cell mediatedimmune mechanisms in the pathogenesis ofCrohn's disease: leadingarticle, 1

Crypt celi proliferationAnalysis of crypt cell proliferation in coeliac disease using MI-BI

antibody shows and increase in growth function, 22Intestinal proliferation in coeliac disease: looking into the crypt:

leading article, 321Cyclosporin, Cyclosporin in the treatment of corticosteroid resistant

autoimmune chronic active hepatitis, 459Cytochrome P4501A2, Caffeine phenotyping of cytochrome P4501A2,

N-acetyltransferase, and xanthine oxidase in patients with familialadenomatous polyposis, 251

Cytochrome P450, Characterisation of CYP3A gene subfamily expres-sion in human gastrointestinal tissues, 259

Cytophotometry, Cytophotometric and flow cytometric DNA contentof isolated glands in gastric neoplasia, 516

Day surgery, Day surgery and gastroenterology: leading article, 324Death rate, Rising death rate from non-malignant disease of the

oesophagus in England and Wales, 488Defecography, Relationships between defecographic findings, rectal

emptying, and colonic transit time in constipated patients, 907Denmark, Prevalence and incidence of peptic ulcer disease in a Danish

County, 819Deoxycholic acid

Deoxycholic acid in gall bladder bile does not account for theshortened nucleation time in patients with cholesterol gall stones,121

Unconjugated secondary bile acids in the serum of patients withcolorectal adenomas, 268

Diabetes mellitus, Seroconversion of reticulin autoantibodies predictscoeliac disease in insulin dependent diabetes mellitus, 239

DiarrhoeaBacterial translocation in the rat model of lectin induced diarrhoea,

379Natural history and prognosis of diarrhoea of unknown cause in

patients with acquired immunodeficiency syndrome (AIDS), 283Diet, Rat intestinal mucosal responses to a microbial flora and different

diets, 209Dietary fibre, Gastric emptying of a solid meal is accelerated by the

removal of dietary fibre naturally present in food, 825Dilatation, Efficacy and safety of hydrostatic balloon dilatation of

ileocolonic Crohn's strictures: a prospective longterm analysis, 577

Volume 36: Subject index -Main headings

Direct access endoscopy, Serology for Helicobacter pylori comparedwith symptom questionnaires in screening before direct accessendoscopy, 330

Diverticular disease, Prospective study of physical activity and the riskof symptomatic diverticular disease in men, 276

DNA flow cytometry, DNA flow cytometric evaluation of cell cycledistribution in ulcerative colitis: a proposed method for assessingseverity of disease, 50

Duodenal neoplasms, Caffeine phenotyping of cytochrome P4501A2,N-acetyltransferase, and xanthine oxidase in patients with familialadneomatous polyposis, 251

Duodenal pH, High pH reduces DNA damage caused by bile frompatients with familial adenomatous polyposis: antacids mayattenuate duodenal polyposis, 918

Duodenal ulcerA substantial proportion of non-ulcer dyspepsia patients have thesame abnormality of acid secretion as duodenal ulcer patients, 534

Death from malignant disease after surgery for duodenal ulcer:correspondence, 475

Duodenal ulcer, gastric acid, and Helicobacter pylori: correspondence,152

Helicobacter pylori infection does not reduce the viscosity of humangastric mucus gel, 327

Prevalence and incidence of peptic ulcer disease in a Danish County,819

Duodenal ulcer diseaseHelicobacter pyloni eradication in the African setting, with special

reference to reinfection and duodenal ulcer recurrence, 544Helicobacter pylori reinfection with identical organisms: transmission

by the patients' spouses, 831Duodenogastric reflux, Profound duodenogastric reflux causes pan-

creatic growth in rats, 137: correspondence, 943Duodenum

Chloride dependent amino acid transport in the human smallintestine, 215

Effect of Helicobacter pylori eradication on gastric metaplasia of theduodenum, 193

Tyrosine phosphorylation in the human duodenum, 34DyspepsiaA substantial proportion of non-ulcer dyspepsia patients have thesame abnormality of acid secretion as duodenal ulcer patients,534

Importance of reflux symptoms in functional dyspepsia, 189

Echinococcus of the liver, Echinococcus of the liver: correspondence,947

Ecstasy induced hepatitis, Ecstasy induced hepatitis mimicking viralhepatitis, 939

Electrolyte transport, Immune regulation of human colonic electrolytetransport in vitro, 395

Emergencies, Surgical emergencies in tropical gastroenterology: leadingarticle, 9

Endocytosis of gliadin, Translocation of gliadin into HLA-DR antigencontaining, lysosomes in coeliac disease, 703

Endoscopic gail stone fragmentation, Holmium-YAG laser for gallstone fragmentation: an endoscopic tool, 442

Endoscopic retrograde cholangiopancreatographyA three year follow up of selfexpanding metal stents in the endoscopic

palliation of longterm survivors with malignant biliary obstruction,618

Detection of c-Ki-ras gene codon 12 mutations from pancreatic ductbrushings in the diagnosis of pancreatic tumours, 781

Endoscopic sphincterotomy, Retained common bile duct stones afterendoscopic sphincterotomy: temporary and longterm treatmentwith biliary stenting, 446

EndoscopyEndoscopic detection of ischaemia with a new probe indicates low

oxygenation of gastric epithelium in portal hypertensive gastro-pathy, 654

Gastroenterology in the Trent Region in 1992 and a review of changessince 1975, 468

Light ofmy life: personal viewpoint, 796Prospective audit of upper gastrointestinal endoscopy in two regions

of England: safety, staffing, and sedation methods, 462Recent advances in the endoscopic management of variceal bleeding:.

leading article, 647Serology for Helicobacter pylori compared with symptom question-

naires in screening before direct access endoscopy, 330The nurse endoscopist: special report, 795

Endotoxaemia, Significance of systemic endotoxaemia in inflammatorybowel disease, 897

Energy balance, Energy expenditure and substrate metabolism inpatients with cirrhosis of the liver: effects of the pattern of foodintake, 110

Energy intake, Relation between gastric emptying rate and energyintake in children compared with adults, 183

Volume 36: Subject index - Main headings

Enteral nutrition, Luminal nutrition and gut growth: correspondence,943

Environmental factors, Low prevalence of primary biliary cirrhosis inVictoria, Australia, 927

Enzyme activity, Studies on the expression of intestinal lactase indifferent individuals, 28

Epidermal growth factors, Effect of gonadectomy on epidermal growthfactor values in the gastrointestinal tract of male and female CD-1mice, 558

Escherichia coli, Expression of binding of plasminogen, thrombo-spondin, vitronectin, and fibrinogen, and adhesive properties byEscherichia coli strains isolated from patients with colonic diseases,401

Ethanol, Effects of ethanol and protein deficiency on pancreaticdigestive and lysosomal enzymes, 287

Ethics, Unethical research relating to Helicobacter pylori: correspondence,155

EuropeEuropean cooperation in gastroenterology, 637South Asian and European colitics show characteristic differences in

colonic mucus glycoprotein type and turnover, 696Exercise, Prospective study of physical activity and the risk of

symptomatic diverticular disease in men, 276

Faecal mucin sulphatase, Increased faecal mucin sulphatase activity inulcerative colitis: a potential target for treatment, 570

Faecal occult blood testing, Colorectal cancer screening in asympto-matic populations, 590

Familial adenomatous polyposisCaffeine phenotyping of cytochrome P4501A2, N-acetyltransferase,

and xanthine oxidase in patients with familial adenomatous poly-posis, 251

High pH reduces DNA damage caused by bile from patients withfamilial adenomatous polyposis: antacids may attenuate duodenalpolyposis, 918

Novel germline APC gene mutation in a large familial adenomatouspolyposis kindred displaying variable phenotypes, 731

Proliferative compartment deregulation in the non-neoplastic colonicepithelium of familial adenomatous polyposis, 391

Fanilial disease, Prevalence and pattern of familial disease in primarybiliary cirrhosis, 615

Fast protein liquid chromatography, Purification and assay of secretorylithostathine in human pancreatic juice by fast protein liquidchromatography, 622

Fatty acid binding protein, Intestinal fatty acid binding protein isavailable for diagnosis of intestinal ischaemia, 788

Fatty acid oxidation, Selective inhibition of fatty acid oxidation incolonocytes by ibuprofen: a cause of colitis? 55

Fibreoptic technology, Light ofmy life: personal viewpoint, 796Flow cytometry, Cytophotometric and flow cytometric DNA content of

isolated glands in gastric neoplasia, 516Food allergy, Role of 5-hydroxytryptamine in intestinal water and

electrolyte movement during gut anaphylaxis, 553Food intake, Energy expenditure and substrate metabolism in patients

with cirrhosis of the liver: effects of the pattern of food intake,110

Fulminant hepatic failure, Fulminant hepatic failure caused by tuber-culosis, 792

Gall bladder bile, Deoxycholic acid in gall bladder bile does not accountfor the shortened nucleation time in patients with cholesterol gallstones, 121

Gall bladder motilityEffect of octreotide on fasting gall bladder emptying, antroduodenal

motility, and motilin release in acromegaly, 755Effect of predigested fat on intestinal stimulation of plasma

cholecystokinin and gall bladder motility in coeliac disease, 17Gall stones

Composition of gall bladder stones associated with octreotide:response to oral ursodeoxycholic acid, 126

Deoxycholic acid in gall bladder bile does not account for theshortened nucleation time in patients with cholesterol gall stones,121

Effect of octreotide on fasting gall bladder emptying, antroduodenalmotility, and motilin release in acromegaly, 755

Holmium-YAG laser for gall stone fragmentation: an endoscopic tool,442

Prevalence ofHelicobacter pylori in patients with gall stones before andafter cholecystectomy, 675

Gastric acidAcid and gastric metaplasia in the duodenum: correspondence, 154Duodenal ulcer, gastric acid, and Helicobacter pyloi: correspondence,

152Gastric acid secretion, Relation of acupuncture and vagal gastric acid

secretion: correspondence, 800

Gastric cancerCell proliferation in Helicobacter pylon associated gastritis and the

effect of eradication therapy, 346Chronology ofp53 protein accumulation in gastric carcinogenesis, 848Helicobacter pylori associated with a high prevalence of duodenal ulcer

disease and a low prevalence ofgastric cancer in a developing nation,198

Preservation of the spleen improves survival after radical surgery forgastric cancer, 684

Gastric carcinoma, A variant alkaline phosphatase found in a case ofgastric carcinoma with super bone scan, 299

Gastric emptyingGastric emptying of a solid meal is accelerated by the removal of

dietary fibre naturally present in food, 825Relation between gastric emptying rate and energy intake in childrencompared with adults, 183

Gastric epithelial proliferation, Accelerated gastric epithelial prolifera-tion, 522

Gastric juice, Pharmacological manipulation of gastric juice:thrombelastographic assessment and implications for treatment ofgastrointestinal haemorrhage, 358

Gastric lymphoma, Primary gastric lymphoma in clinical practice1973-1992,679

Gastric metaplasiaAcid and gastric metaplasia in the duodenum: correspondence, 154Effect of Helicobacter pylori eradication on gastric metaplasia of theduodenum, 193

Gastric mucosaCell proliferation in the gastric corpus in Helicobacter pylori associated

gastritis and after gastric resection, 351Effect ofcapsaicin and chilli on ethanol induced gastric mucosal injury

in the rat, 664Helicobacter pylori infection does not reduce the viscosity of human

gastric mucus gel, 327Mucosal erosions in longterm non-steroidal anti-inflammatory drug

users: predisposition to ulceration and relation to Helicobacterpylori, 334

Muscarinic receptors in gastric mucosa are increased in peptic ulcerdisease, 813

Nitric oxide synthase in gastric mucosa: correspondence, 942Gastric neoplasia, Cytophotometric and flow cytometric DNA content

of isolated glands in gastric neoplasia, 516Gastric relaxation, Impaired gastric relaxation in patients with

achalasia, 363Gastric resection, Cell proliferation in the gastric corpus in Helicobacter

pylori associated gastritis and after gastric resection, 351Gastric ulcerCure of peptic gastric ulcer associated with eradication of Helicobacter

pylori, 834Prevalence and incidence of peptic ulcer disease in a Danish County,819

Gastrin, Gastrin and the growth of the gastrointestinal tract, 203Gastrin releasing peptide, A substantial proportion of non-ulcer

dyspepsia patients have the same abnormality of acid secretion asduodenal ulcer patients, 534

GastritisCell proliferation in the gastric corpus in Helicobacter pylori associated

gastritis and after gastric resection, 351Cell proliferation in Helicobacter pylon associated gastritis and the

effect of eradication therapy, 346Interferon gamma and interleukin 4 secreting cells in the gastricantrum in Helicobacter pylori positive and negative gastritis, 341

Gastro-oesophageal refluxIntegrity and characteristics of secondary oesophageal peristalsis in

patients with gastro-oesophageal reflux disease, 499Precipitating causes of acid reflux episodes in ambulant patients with

gastro-oesophageal reflux disease, 505Psychological factors in gastro-oesophageal reflux disease: leading

article, 481Twenty to 40 year follow up of infantile hiatal hernia, 809

GastroenterologyDay surgery and gastroenterology: leading article, 324European cooperation in gastroenterology, 637Gastroenterology in Romania: a fresh start in a new era, 473Gastroenterology in the Trent Region in 1992 and a review of changes

since 1975, 468Gastrointestinal diseaseA population based study of Helicobacterpylori infection in a European

country: the San Marino Study. Relations with gastrointestinaldiseases, 838

Hyposplenism in gastrointestinal disease: leading article, 165Gastrointestinal haemorrhage

Acute gastrointestinal haemorrhage in patients treated with anti-coagulant drugs: leading article, 483

Pharmacological manipulation of gastric juice: thrombelastographicassessment and implications for treatment of gastrointestinalhaemorrhage, 358

959

960

Recurrent gastrointestinal bleeding associated with chronic

creatitis, 314Gastrointestinal tract, Characterisation of the influence of anti-gastrin,

anti-epidermal growth factor, anti-oestradiol, and anti-luteinising

hormone releasing hormone antibodies on the proliferation

cells lines from the gastrointestinal tract, 220

Gastroparesis, Postprandial function in gastroparesis: correspondence,

798General practice, Reasons for variations in the use of open

gastroscopy by general practitioners, 180

GliadinEffect of gliadin and other food peptides on expression ofMHC

molecules by HT-29 cells, 548

Translocation of gliadin into HLA-DR antigen containing lysosomes

in coeliac disease, 703Wheat deficient in gliadins: promising tool for treatment of

disease, 375Gliadin sensitive T cells, Histological changes in small bowel

induced by gliadin sensitive T lymphocytes can be blocked

interferon gamma antibody, 874

Gluten free diet, Osteoporosis in treated adult coeliac disease,

Gluten sensitive enteropathy, Seroconversion of reticulin

tibodies predicts coeliac disease in insulin dependent diabetes

mellitus, 239Gonadectomy, Effect of gonadectomy on epidermal growth

values in the gastrointestinal tract of male and female CD-1 mice,

558Growth control, Gastrin and the growth of the gastrointestinal tract,

Growth factorsCharacterisation of the influence of anti-gastrin, anti-epidermal

growth factor, anti-oestradiol, and anti-luteinising hormone releas-

ing hormone antibodies on the proliferation of 27 cells lines from

gastrointestinal tract, 220Stimulation and inhibition of proliferation in the small intestinal

crypts of the mouse after in vivo administration of growth factors,

864Guaiac occult blood test, Diagnostic value of a guaiac occult

and faecal alpha 1-antitrypsin, 87

Gut anaphylaxis, Role of 5-hydroxytryptamine in intestinal water

electrolyte movement during gut anaphylaxis, 553

Gut growth, Luminal nutrition and gut growth: correspondence,

Haemochromatosis, Increased PiZ gene frequency for antitrypsin

patients with genetic haemochromatosis, 922

HelicobacterpyloriA population based study of Helicobacterpylori infection in a

country: the San Marino Study. Relations with gastrointestinal

diseases, 838A substantial proportion of non-ulcer dyspepsia patients

same abnormality of acid secretion as duodenal ulcer patients,

Cell proliferation in the gastric corpus in Helicobacter pylori associated

gastritis and after gastric resection, 351

Cell proliferation in Helicobacter pylori associated gastritis and

effect of eradication therapy, 346

Changes in the intragastric distribution of Helicobacter pyloritreatment with omeprazole, 12

Cure of peptic gastric ulcer associated with eradication of Helicobacter

pylori, 834

Detection of the intragastric sites at which Helicobacter pyloritreatment with amoxycillin and cimetidine, 670

Duodenal ulcer, gastric acid, and Helicobacterpylori: correspondence,

152

Effect of Helicobacter pyloni eradication on gastric metaplasia

duodenum, 193Effect of Helicobacterpylori status on intragastric pH during

with omeprazole, 539Effect of a test meal on the intragastric distribution of

'3C-urea breath test for Helicobacterpyloni, 337

Helicobacterpylori associated with a high prevalence of duodenal

disease and a low prevalence of gastric cancer in a developing nation,

198

Helicobacter pyloni eradication in the African setting, with

reference to reinfection and duodenal ulcer recurrence, 544

Helicobacterpylori infection does not reduce the viscosity

gastric mucus gel, 327

Helicobacter pyloni reinfection with identical organisms: transmission

the patients 'spouses,831

High Helicobacter pyloni numbers are associated with low eradication

rate after triple therapy, 845

Interferon gamma and interleukin 4 secreting cells in

antrum in Helicobacter pyloni positive and negative gastritis,

MMnntrier's disease: correspondence, 945

Mucosal erosions in longterm non-steroidal anti-inflammatory

users: predisposition to ulceration and relation to Helicobacter

pylori, 334

Neutrophil degranulation by Helicobacterpylori proteins, 354

Volume 36: Subject index - Main headings

Prevalence of Helicobacterpylori in patients with gall stones before andafter cholecystectomy, 675

Primary gastric lymphoma in clinical practice 1973-1992, 679Serology for Helicobacter pylori compared with symptom question-

naires in screening before direct access endoscopy, 330Unethical research relating to Helicobacter pylori: correspondence, 155

Hepatic acute phase protein, Pancreatic cancer cell derived IL-8stimulates hepatic acute phase protein production in vitro andserum IL-8 correlates with serum CRP in pancreatic cancer patientsin vivo, A479

Hepatic acute phase response, PBMC regulation of the heaptic acutephase response (APPR) in cancer patients occurs via an IL-6dependent mechanism, A479

Hepatic venous outflow, Hepatic venous outflow obstruction in patientswith polycystic liver disease: pathogenesis and treatment, 142

Hepatic venous pressure, Portal and systemic haemodynamic response

to acute and chronic administration of low and high doseisosorbide-5-mononitrate in patients with cirrhosis, 104

HepatitisCyclosporin in the treatment of corticosteroid resistant autoimmune

chronic active hepatitis, 459Failure to incriminate hepatitis B, hepatitis C, and hepatitis E viruses

in the aetiology of fulminant non-A non-B hepatitis, 433Hepatitis induced by traditional Chinese herbs: possible toxic compo-

nents, 146Hepatitis B virus, Adenine arabinoside 5'-monophosphate in patients

with chronic hepatitis B: comparison of the efficacy in patients withhigh and low viral replication, 422

Hepatitis CAcute hepatitis C infection after sexual exposure, 148Chronic hepatitis C virus infections: predictive value of genotype and

level of viraemia on disease progression and response to interferona,427

Liver cytosolic 1 antigen-antibody system in type 2 autoimmunehepatitis and hepatitis C virus infection, 749

Serum intercellular adhesion molecule-i levels in chronic hepatitis C:association with disease activity and response to interferona, 599

Hepatocellular carcinomaIncreased PiZ gene frequency fora, antitrypsin in patients with

genetic haemochromatosis, 922Liver transplantation for hepatocellular carcinoma: leading article, 644

Hereditary non-polyposis colorectal carcinomaAnalysis of Ha-ras 1 allele frequencies in hereditary non-polyposis

colorectal cancer, 382Variables associated with the risk of colorectal adenomas in asymp-

tomatic patients with a family history of colorectal cancer, 385Hiatal hernia, Twenty to 40 year follow up of infantile hiatal hernia, 809High performance liquid chromatography, Quantification of human

lithostathine by high performance liquid chromatography, 630HLA-DR antigen, Translocation of gliadin into HLA-DR antigen

containing lysosomes in coeliac disease, 703HLA molecules, Constitutive and cytokine induced expression of HLA

molecules, secretory component, and intercellular adhesion mole-cule-i is modulated by butyrate in the colonic epithelial cell lineHT-29, 737

Holmium-YAG laser, Holmium-YAG laser for gall stone fragmenta-tion: an endoscopic tool, 442

Hormones, Characterisation of the influence of anti-gastrin, anti-epidermal growth factor, anti-oestradiol, and anti-luteinising hor-mone releasing hormone antibodies on the proliferation of 27 cellslines from the gastrointestinal tract, 220

HT-29 celis, Effect of gliadin and other food peptides on expression ofMHC class II molecules by HT-29 cells, 548

Hydrostatic bailoon dilatation, Efficacy and safety of hydrostaticballoon dilatation of ileocolonic Crohn's strictures: a prospectivelongterm analysis, 577

5-Hydroxytryptamine, Role of 5-hydroxytryptamine in intestinal waterand electrolyte movement during gut anaphylaxis, 553

Hyposplenism, Hyposplenism in gastrointestinal disease: leading article,165

IbuprofenIbuprofen versus placebo in the treatment of pancreatic cancer

cachexia, A479Selective inhibition of fatty acid oxidation in colonocytes byibuprofen: a cause of colitis?, 55

Ileitis, Duration of recurrent ileitis after ileocolonic resection correlateswith presurgical extent of Crohn's disease, 715

Ileocaecal transit, Scintigraphic measurement of ileocaecal transitin irritable bowel syndrome and chronic idiopathic constipation,585

Ileocolonic resection, Duration of recurrent ileitis after ileocolonicresection correlates with presurgical extent of Crohn's disease,715

Immune mediated liver disease, Soluble adhesion molecules in immunemediated liver disease: leading article, 806

Volume 36: Subject index - Main headings

Immunogold electron microscopy, Persistent measles virus infection ofthe intestine: confirmation by immunogold electron microscopy,564

In situ hybridisation, Characterisation of CYP3A gene subfamilyexpression in human gastrointestinal tissues, 259

Incidence, Prevalence and incidence of peptic ulcer disease in a DanishCounty, 819

Infectious mononucleosis, Fatal infectious mononucleosis: a severecomplication in the treatment of Crohn's disease with azathioprine,311

Inflammatory bowel diseaseAdhesion molecules in inflammtory bowel disease, 724Evaluation of intestinal permeability in patients with inflammatory

bowel disease using lactulose and measuring antibodies to lipid A,891

Increased expression of cell adhesion molecule P-selectin in activeinflammatory bowel disease, 411

P-ANCA in monozygotic twins with inflammatory bowel disease, 887Platelet dysfunction: a new dimension in inflammtory bowel disease:

leading article, 5Quantification of inflammatory bowel disease activity using techne-tium-99m HMPAO labelled leucocyte single photon emissioncomputerised tomography, 243

Significance of systemic endotoxaemia in inflammatory bowel disease,897

Soluble interleukin-6 receptors in inflammatory bowel disease: rela-tion to circulating interleukin-6, 45

Interferon alphaChronic hepatitis C virus infections: predictive value of genotype and

level of viraemia on disease progression and response to interferona,427

Serum intercellular adhesion molecule-1 levels in chronic hepatitis C:association with disease activity and response to interferon a, 599

Interferon gammaAscitic fluid gamma interferon concentrations and adenosine

deaminase activity in tuberculous peritonitis, 419Histological changes in small bowel mucosa induced by gliadin

sensitive T lymphocytes can be blocked by anti-interferon gammaantibody, 874

Interferon gamma and interleukin 4 secreting cells in the gastricantrum in Helicobacter pylori positive and negative gastritis, 341

Interleukin 4, Interferon gamma and interleukin 4 secreting cells in thegastric antrum in Helicobacter pylori positive and negative gastritis,341

Interleukin-6, Soluble interleukin-6 receptors in inflammatory boweldisease: relation to circulating interleukin-6, 45

Interleukin-8, Pancreatic cancer cell derived IL-8 stimulates hepaticacute phase protein production in vitro and serum IL-8 correlateswith serum CRP in pancreatic cancer patients in vivo, A479

Internal anal sphincter hypertrophy, Hereditary proctalgia fugax andconstipation: report of a second family, 581

Intestinal epithelial cell proliferation, Novel insights into humanintestinal epithelial cell proliferation in health and disease usingconfocal microscopy, 369

Intestinal ischaemia, Intestinal fatty acid binding protein is available fordiagnosis of intestinal ischaemia, 788

Intestinal mucosa, Rat intestinal mucosal responses to a microbial floraand different diets, 209

Intestinal permeability, Evaluation of intestinal permeability in patientswith inflammatory bowel disease using lactulose and measuringantibodies to lipid A, 891

Intestinal proliferation, Intestinal proliferation in coeliac disease:looking into the crypt: leading article, 321

Intraepithelial lymphocytes, Microscopic colitis syndrome, 880Intragastric distribution, Changes in the intragastric distribution of

Helicobacter pylori during treatment with omeprazole, 12Intragastric pH-metry, Effect ofHelicobacterpylori status on intragastric

pH during treatment with omeprazole, 539Intraluminal gastric pH, Intraluminal gastric pH in chronic pan-

creatitis, 294Irritable bowel syndrome, Scintigraphic measurement of ileocaecal

transit in irritable bowel syndrome and chronic idiopathic constipa-tion, 585

Ischaemia, Endoscopic detection of ischaemia with a new probeindicates low oxygenation of gastric epithelium in portal hyper-tensive gastropathy, 654

Isosorbide-5-mononitrate, Portal and systemic haemodynamicresponse to acute and chronic administration of low and high doseisosorbide-5-mononitrate in patients with cirrhosis, 104

Jaundice, Ecstasy induced hepatitis mimicking viral hepatitis, 939

Ki-67 antigen, Proliferative compartment deregulation in the non-neoplastic colonic epithelium of familial adenomatous polyposis,391

Ki-ras gene mutation, Detection of c-Ki-ras gene codon 12 mutationsfrom pancreatic duct brushings in the diagnosis of pancreatictumours, 781

Ki-ras mutation, Detection of c-Ki-ras mutations in faecal samples fromsporadic colorectal cancer patients, 81

Labelling index, Stimulation and inhibition of proliferation in the smallintestinal crypts of the mouse after in vivo administration of growthfactors, 864

Lactase, Studies on the expression of intestinal lactase in differentindividuals, 28

Lactulose, Evaluation of intestinal permeability in patients withinflammatory bowel disease using lactulose and measuring anti-bodies to lipid A, 891

Laparoscopic biliary bypass, Laparoscopic biliary and gastric bypass:a useful adjunct in the treatment of carcinoma of the pancreas,778

Laparoscopic cholecystectomy, Laparoscopic cholecystectomy: lead-ing article, 161

Laparoscopic gastric bypass, Laparoscopic biliary and gastric bypass: auseful adjunct in the treatment of carcinoma of the pancreas, 778

Laparotomy, Laparoscopic biliary and gastric bypass: a useful adjunctin the treatment of carcinoma of the pancreas, 778

Laser, Holmium-YAG laser for gall stone fragmentation: an endoscopictool, 442

Lauren classification, Chronology of p53 protein accumulation ingastric carcinogenesis, 848

Lectin, Bacterial translocation in the rat model of lectin induceddiarrhoea, 379

Leukotrienes, Misoprostol inhibits gastric mucosal release of endo-genous prostaglandin E2 and thromboxane B, in healthy volunteers,511

Lexipafant, A double-blind placebo controlled study of lexipafant(a potent PAF antagonist) in acute pancreatitis, A478

Lipid A, Evaluation of intestinal permeability in patients with inflamma-tory bowel disease using lactulose and measuring antibodies to lipidA,891

Lipid digestion, Effect of predigested fat on intestinal stimulation ofplasma cholecystokinin and gall bladder motility in coeliac disease,17

Lithium gamma linolenic acid, Cytotoxicity of lithium gamma linolenicacid on pancreatic carcinoma cell lines in vitro, A477

LithostathinePurification and assay of secretory lithostathine in human pancreatic

juice by fast protein liquid chromatography, 622Quantification of human lithostathine by high performance liquid

chromatography, 630Liver

Artificial livers - what's keeping them? leading article, 168Indications, methods, and outcomes of percutaneous liver biopsy in

England and Wales: an audit by the British Society ofGastroentero-logy and the Royal College of Physicians of London, 437

Liver cytosolic antigen-antibody, Liver cytosolic 1 antigen-antibodysystem in type 2 autoimmune hepatitis and hepatitis C virusinfection, 749

Liver disease, Soluble adhesion molecules in immune mediated liverdisease: leading article, 806

Liver failure, Failure to incriminate hepatitis B, hepatitis C, andhepatitis E viruses in the aetiology of fulminant non-A non-Bhepatitis, 433

Liver transplantation, Liver transplantation for hepatocellular car-cinoma: leading article, 644

Liver tumour, Octreotide, the reticuloendothelial system, and experi-mental liver tumour, 610

Lower oesophageal sphincter pressure, Effect of cholecystokinin onlower oesophageal sphincter pressure and transient loweroesophageal sphincter relaxations in humans, 39

Luminal nutrition, Luminal nutrition and gut growth: correspondence,943

Lung injury, Acute lung injury in the microembolic model of acutepancreatitis, A478

Lymphoma, Primary gastric lymphoma in clinical practice 1973-1992,679

Magnetic resonance imagingDynamic contrast enhanced magnetic resonance imaging is superior todynamic computed tomography in acute pancreatitis, A478

Pelvic and perineal complications ofCrohn's disease: assessment usingmagnetic resonance imaging, 407

Major histocompatibility, Effect of gliadin and other food peptides onexpression ofMHC class II molecules by HT-29 cells, 548

Major histocompatibility complex, Autoimmunity and chronic pan-creatitis: correspondence, 799

Mast cell secretion, Immune regulation of human colonic electrolytetransport in vitro, 395

961

Volume 36: Subject index - Main headings

Measles virus, Persistent measles virus infection of the intestine:confirmation by immunogold electron microscopy, 564

Menetrier's disease,Menetrier's disease: correspondence, 945Messenger RNA, Studies on the expression of intestinal lactase in

different individuals, 28Metalloproteinase, Collagenase, stromelysin, and tissue inhibitor of

metalloproteinase expression in pancreatic and ampullary cancer,A477

Metastasis, Current concepts in metastasis: correspondence, 1533,4-Methylenedioxymetamphetamine (MDMA), Ecstasy induced

hepatitis mimicking viral hepatitis, 939MI-Bl antibody, Analysis of crypt cell proliferation in coeliac disease

using MI-B 1 antibody shows an increase in growth function, 22Microbial flora, Rat intestinal mucosal responses to a microbial flora and

different diets, 209Microembolic model, Acute lung injury in the microembolic model of

acute pancreatitis, A478Microscopic colitis, Microscopic colitis syndrome, 880Misoprostol, Misoprostol inhibits gastric mucosal release of endo-

genous prostaglandin E2 and thromboxane B2 in healthy volunteers,511

Monoclonal antibody, Proliferative compartment deregulation in thenon-neoplastic colonic epithelium of familial adenomatous poly-posis, 391

Motilin, Effect of octreotide on fasting gall bladder emptying,antroduodenal motility, and motilin release in acromegaly, 755

MotiityDifferential regional effects of octreotide on human gastrointestinalmotor function, 743

Effect of octreotide on fasting gall bladder emptying, antroduodenalmotility, and motilin release in acromegaly, 755

Mucin sulphatase, Inceased faecal mucin sulphatase activity in ulcera-tive colitis: a potential target for treatment, 570

Mucus glycoprotein type, South Asian and European colitics showcharacteristic differences in colonic mucus glycoprotein type andturnover, 696

Muscarinic receptors, Muscarinic receptors in gastric mucosa areincreased in peptic ulcer disease, 813

Mutagen activation, Characterisation of CYP3A gene subfamilyexpression in human gastrointestinal tissues, 259

Mycobacterium paratuberculosis, Mycobacterium paratuberculosis andCrohn's disease: corespondence, 942

N-acetyltransferase, Caffeine phenotyping of cytochrome P4501A2,N-acetyltransferase, and xanthine oxidase in patients with familialadenomatous polyposis, 251

Neutrophils, Neutrophil degranulation byHelicobacterpylori proteins, 354Nitric oxide, Enhanced colonic nitric oxide generation and nitric oxide

synthase activity in ulcerative colitis and Crohn's disease, 718Nitric oxide synthase, Nitric oxide synthase in gastric mucosa:

correspondence, 942Non-A non-B hepatitis, Failure to incriminate hepatitis B, hepatitis C,

and hepatitis E viruses in the aetiology of fulminant non-A non-Bhepatitis, 433

Non-Hodgkin's lymphoma, Colitis ulcerosa complicated by malignantlymphoma: case report and analysis of published works, 306

Non-malignant disease ofthe oesophagus, Rising death rate from non-malignant disease of the oesophagus in England and Wales, 488

Non-steroidal anti-inflammatory drugsMucosal erosions in longterm non-steroidal anti-inflammatory drug

users: predisposition to ulceration and relation to Helicobacterpylori, 334

Non-steroidal anti-inflammatory drugs and prostaglandin effects onpepsinogen secretion by dispersed human peptic cells, 657

NSAIDs and the chemoprevention of colon and oesophageal cancer:correspondence, 153

Notes, 157, 476, 640, 948Nucleation time, Deoxycholic acid in gall bladder bile does not account

for the shortened nucleation time in patients with cholesterol gallstones, 121

Nurse endoscopist, The nurse endoscopist: special report, 795Nutrition, Luminal nutrition and gut growth: correspondence, 943

Obesity, Satiety effects of a physiological dose of cholecystokinin inhumans, 176

Obituary, Dr Eru Pomare, 802Octreotide

Composition of gall bladder stones associated with octreotide:response to oral ursodeoxycholic acid, 126

Differential regional effects of octreotide on human gastrointestinalmotor function, 743

Effect of octreotide on fasting gall bladder emptying, antroduodenalmotility, and motilin release in acromegaly, 755

Octreotide, the reticuloendothelial system, and experimental livertumour, 610

Treatment of pain in chronic pancreatitis by inhibition of pancreaticsecretion with octreotide, 450

Oesophageal acid, Importance of reflux symptoms in functionaldyspepsia, 189

Oesophageal cancerCancer of the oesophagus: correspondence, 153NSAIDs and the chemoprevention of colon and oesophageal cancer:

correspondence, 153Oesophageal peristalsis, Integrity and characteristics of secondary

oesophageal peristalsis in patients with gastro-oesophageal refluxdisease, 499

Oesophageal secretion, Effect of topical oesophageal acidification onhuman salivary and oesophageal alkali secretion, 649

Oesophagus, Rising death rate from non-malignant disease of theoesophagus in England and Wales, 488

Oligopeptide diet, Controlled trial of oligopeptide versus amino aciddiet in treatment of active Crohn's disease, 60

OmeprazoleAccelerated gastric epithelial proliferation, 522Changes in the intragastric distribution of Helicobacter pylon during

treatment with omeprazole, 12Effect of Helicobacterpylori status on intragastric pH during treatment

with omeprazole, 539Omeprazole 10 mg or 20 mg once daily in the prevention of recurrence

of reflux oesophagitis, 492Open access gastroscopy, Reasons for variations in the use of open

access gastroscopy by general practitioners, 180Osteoporosis, Osteoporosis in treated adult coeliac disease, 710

p53 proteinAntibodies against p53 protein in serum of patients with benign or

malignant pancreatic and biliary diseases, 455Chronology of p53 protein accumulation in gastric carcinogenesis,

848Colorectal tumorigenesis: correspondence, 801Expression of mutant p53 protein and CD44 variant proteins in

colorectal tumorigenesis, 76P-ANCA, P-ANCA in monozygotic twins with inflammatory bowel

disease, 887P-selectin, Increased expression of cell adhesion molecule P-selectin in

active inflammatory bowel disease, 411Pain, Treatment of pain in chronic pancreatitis by inhibition of

pancreatic secretion with octreotide, 450Pancreatic cancer (carcinoma)

Antibodies against p53 protein in serum of patients with benign ormalignant pancreatic and biliary diseases, 455

Collagenase, stromelysin, and tissue inhibitor of metalloproteinaseexpression in pancreatic and ampullary cancer, A477

Cytotoxicity of lithium gamma linolenic acid on pancreatic carcinomacell lines in vitro, A477

Detection of c-Ki-ras gene codon 12 mutations from pancreatic ductbrushings in the diagnosis of pancreatic tumours, 781

Diagnosis of pancreatic cancer by 2['8F]-fluoro-2-deoxy-D-glucosepositron emission tomography, 771

Ibuprofen versus placebo in the treatment of pancreatic cancercachexia, A479

Isolation of a novel gene rearranged and overexpressed in pancreaticcancer, A477

Laparoscopic biliary and gastric bypass: a useful adjunct in thetreatment of carcinoma of the pancreas, 778

Pancreatic cancer cell derived IL-8 stimulates hepatic acute phaseprotein production in vitro and serum IL-8 correlates with serumCRP in pancreatic cancer patients in vivo, A479

Pancreatic carcinoma: an audit of treatment, survival, and quality oflife, A479

PBMC regulation of the hepatic acute phase response (APPR)in cancer patients occurs via an IL-6 dependent mechanism,A479

The acute phase response and survival in pancreatic cancer, A479Tissue factor and tissue factor pathway inhibitor in human pancreatic

carcinoma, A479Tumour specific targeting of prodrug activation as gene therapy for

pancreatic cancer, A477Pancreatic disease, Secretin induces a paradoxical sphincter of oddi

hyperpressure effect in alcoholic patients without pancreaticdisease, A477

Pancreatic enzymes, Effects of ethanol and protein deficiency onpancreatic digestive and lysosomal enzymes, 287

Pancreatic growth, Profound duodenogastric reflux causes pancreaticgrowth in rats, 137: correspondence, 943

Pancreatic injury, Increased serum pancreatitis associated protein(PAP) concentration after longterm alcohol consumption: furtherevidence for regular subclinical pancreatic damage after heavydrinking?, 117

Pancreatic insufficiency, Intraluminal gastric pH in chronic pan-creatitis, 294

962

Volume 36: Subject index - Main headings

PancreatitisA double-blind placebo controlled study of lexipafant (a potent PAF

antagonist) in acute pancreatitis, A478Acute lung injury in the microembolic model of acute pancreatitis,A478

Autoimmunity and chronic pancreatitis: correspondence, 799Current views on the pathophysiology of acute biliary pancreatitis:

leading article, 803Detection of c-Ki-ras gene codon 12 mutations from pancreatic duct

brushings in the diagnosis of pancreatic tumours, 781Dynamic contrast enhanced magnetic resonance imaging is superior todynamic computed tomography in acute pancreatitis, A478

Intraluminal gastric pH in chronic pancreatitis, 294Pancreatic vascular regulation in chronic pancreatitis in cats, 133Purification and assay of secretory lithostathine in human pancreatic

juice by fast protein liquid chromatography, 622Quantification of human lithostathine by high performance liquid

chromatography, 630Recurrent gastrointestinal bleeding associated with chronic pan-

creatitis, 314Treatment of pain in chronic pancreatitis by inhibition of pancreatic

secretion with octreotide, 450Which clinical prognostic score for acute pancreatitis? Results of a

prospective multicentre study of 719 episodes, A478Which complications of acute pancreatitis are most lethal? A prospec-

tive multicentre clinical study of 719 episodes, A478Pancreatography, Is biliary lithiasis associated with pancreatographic

changes? 761PAP concentration, Increased serum pancreatitis associated protein

(PAP) concentration after longterm alcohol consumption: furtherevidence for regular subclinical pancreatic damage after heavydrinking?, 117

Pepsinogen, Non-steroidal anti-inflammatory drugs and prostaglandineffects on pepsinogen secretion by dispersed human peptic cells,657

Peptic ulcerDeath from malignant disease after surgery for duodenal ulcer:

correspondence, 475Helicobacter pylori infection does not reduce the viscosity of human

gastric mucus gel, 327Peptic ulcer disease

Helicobacter pylori associated with a high prevalence of duodenal ulcerdisease and a low prevalence ofgastric cancer in a developing nation,198

Muscarinic receptors in gastric mucosa are increased in peptic ulcerdisease, 813

Prevalence and incidence of peptic ulcer disease in a Danish County,819

Peristalsis, Integrity and characteristics of secondary oesophagealperistalsis in patients with gastro-oesophageal reflux disease, 499

Peritonitis, Increased CA 125 in a patient with tuberculous peritonitis:case report and review of published works, 303

Pernicious anaemia, Functional defect of T cells in autoimmunegastritis, 171

Peyer's patches, Expression of adhesion molecules in human Peyer'spatches: correspondence, 944

Photodynamic therapyPhotodynamic therapy for malignant tumours of the ampulla ofVater,

853Photosensitisation and photodynamic therapy of oesophageal,

duodenal, and colorectal tumours using 5 aminolaevulinic acidinduced protoporphyrin IX, 67

Physical activity, Prospective study of physical activity and the risk ofsymptomatic diverticular disease in men, 276

PiZ, Increased PiZ gene frequency for a, antitrypsin in patients withgenetic haemochromatosis, 922

Platelet dysfunction, Platelet dysfunction: a new dimension in inflam-matory bowel disease: leading article, 5

Polycystic liver disease, Hepatic venous outflow obstruction in patientswith polycystic liver disease: pathogenesis and treatment, 142

Polyethylene glycol, Polyethylene glycol (PEG) as a marker of smallintestinal permeability: correspondence, 946

Population based study, A population based study ofHelicobacter pyloriinfection in a European country: the San Marino Study. Relationswith gastrointestinal diseases, 838

Portal hypertensive gastropathy, Endoscopic detection of ischaemiawith a new probe indicates low oxygenation of gastric epithelium inportal hypertensive gastropathy, 654

Positron emission tomography, Diagnosis of pancreatic cancer by2["F]-fluoro-2-deoxy-D-glucose positron emission tomography,771

Postprandial function, Postprandial function in gastroparesis: corre-spondence, 798

PrevalenceLow prevalence of primary biliary cirrhosis in Victoria, Australia, 927Prevalence and incidence of peptic ulcer disease in a Danish County,

819

Primary biliary cirrhosisAdhesion molecule expression in primary sclerosing cholangitis and

primary biliary cirrhosis, 604Characterisation of patients with a complete biochemical response to

ursodeoxycholic acid, 935Low prevalence of primary biliary cirrhosis in Victoria, Australia, 927Natural history of bacteriuria in women with primary biliary cirrhosis

and the effect of antimicrobial therapy in symptomatic andasymptomatic groups, 931

Prevalence and pattern of familial disease in primary biliary cirrhosis,615

Primary gastric lymphoma, Primary gastric lymphoma in clinicalpractice 1973-1992, 679

Primary sclerosing cholangitis, Adhesion molecule expression inprimary sclerosing cholangitis and primary biliary cirrhosis,604

Proctalgia fugax, Hereditary proctalgia fugax and constipation: reportof a second family, 581

Prodrug activation, Tumour specific targeting of prodrug activation asgene therapy for pancreatic cancer, A477

Proliferating celi nuclear antigen, Accelerated gastric epithelial prolif-eration, 522

ProliferationCell proliferation in the gastric corpus in Helicobacter pylori associated

gastritis and after gastric resection, 351Intestinal proliferation in coeliac disease: looking into the crypt:

leading article, 321Novel insights into human intestinal epithelial cell proliferation in

health and disease using confocal microscopy, 369Proliferative compartment deregulation in the non-neoplastic colonic

epithelium of familial adenomatous polyposis, 391Proliferative index, DNA flow cytometric evaluation of cell cycle

distribution in ulcerative colitis: a proposed method for assessingseverity of disease, 50

ProstaglandinsMisoprostol inhibits gastric mucosal release of endogenous prosta-

glandin E, and thromboxane B, in healthy volunteers, 511Muscarinic M, receptor inhibition reduces gastroduodenal bicarbo-

nate secretion and promotes gastric prostaglandin E2 synthesis inhealthy volunteers, 528

Non-steroidal anti-inflammatory drugs and prostaglandin effects onpepsinogen secretion by dispersed human peptic cells, 657

Protein, Studies on the expression of intestinal lactase in differentindividuals, 28

Protein binding expression, Expression of binding of plasminogen,thrombospondin, vitronectin, and fibrinogen, and adhesive proper-ties by Escherichia coli strains isolated from patients with colonicdiseases, 401

Protein deficiency, Effects of ethanol and protein deficiency onpancreatic digestive and lysosomal enzymes, 287

Protoporphyrin IX, Photosensitisation and photodynamic therapy ofoesophageal, duodenal, and colorectal tumours using 5aminolaevulinic acid induced protoporphyrin IX, 67

Psychological factors, Psychological factors in gastro-oesophagealreflux disease: leading article, 481

Purine nucleoside, Adenine arabinoside 5'-monophosphate in patientswith chronic hepatitis B: comparison of the efficacy in patients withhigh and low viral replication, 422

Purse string pancreaticojejunostomy, Results of purse string pan-creaticojejunostomy after partial pancreatectomy, A479

Quality of life, Pancreatic carcinoma: an audit of treatment, survival,and quality of life, A479

Questionnaire, Serology for Helicobacterpylori compared with symptomquestionnaires in screening before direct access endoscopy, 330

Radionucfides, Reporting simplified colonic transit studies usingradionucfides: clinician friendly reports, 274

Real time electronic imager, First clinical results with a real time,electronic imager as an aid to colonoscopy, 913

Rectal emptying, Relationships between defecographic findings, rectalemptying, and colonic transit time in constipated patients, 907

Reflux, Importance of reflux symptoms in functional dyspepsia, 189Reflux oesophagitis, Omeprazole 10 mg or 20 mg once daily in the

prevention of recurrence of reflux oesophagitis, 492Reinfection, Helicobacter pylori reinfection with identical organisms:

transmission by the patients' spouses, 831Restorative proctocolectomy, Preservation of complete anal

sphincteric proprioception in restorative proctocolectomy: theinhibitory reflex and fine control of continence need not beimpaired, 902

Reticulin autoantibodies, Seroconversion of reticulin autoantibodiespredicts coeliac disease in insulin dependent diabetes mellitus, 239

Reticuloendothelial system, Octreotide, the reticuloendothelialsystem, and experimental liver tumour, 610

963

964

Retinoid X receptor expression, 1,25-dihydroxyvitamin D3 and reti-noid X receptor expression in human colorectal neoplasms, 255

Romania, Gastroenterology in Romania: a fresh start in a new era, 473Rotavirus infection, Sequential changes in small intestinal structure and

function during rotavirus infection in neonatal rats, 231

SalicylatesAn alternative view of 5-ASA formulations: correspondence, 639New salicylates as maintenance treatment in ulcerative colitis: corres-

pondence, 640Saliva, Effect of topical oesophageal acidification on human salivary and

oesophageal alkali secretion, 649'Sanctuary' sites, Detection of the intragastric sites at which Helicobac-

ter pylori evades treatment with amoxycillin and cimetidine, 670Satiety, Satiety effects of a physiological dose of cholecystokinin in

humans, 176Scintigraphy, Scintigraphic measurement of ileocaecal transit in irrit-

able bowel syndrome and chronic idiopathic constipation, 585ScreeningA screening clinic for relatives of patients with colorectal cancer in a

district general hospital, 90Colorectal cancer screening in asymptomatic populations, 590Variables associated with the risk of colorectal adenomas in asymp-

tomatic patients with a family history of colorectal cancer, 385Secretin, Secretin induces a paradoxical sphincter ofoddi hyperpressure

effect in alcoholic patients without pancreatic disease, A477Sexual exposure, Acute hepatitis C infection after sexual exposure, 148Single photon emission computerised tomography, Quantification of

inflammatory bowel disease activity using technetium-99mHMPAO labelled leucocyte single photon emission computerisedtomography, 243

Small intestineDifferential regional effects of octreotide on human gastrointestinalmotor function, 743

Luminal nutrition and gut growth: correspondence, 943Sequential changes in small intestinal structure and function during

rotavirus infection in neonatal rats, 231Stimulation and inhibition of proliferation in the small intestinal

crypts of the mouse after in vivo administration of growth factors,864

Sodium butyrate, Colonic mucin synthesis is increased by sodiumbutyrate, 93

Solid meal, Gastric emptying of a solid meal is accelerated by theremoval of dietary fibre naturally present in food, 825

SomatostatinDifferential regional effects of octreotide on human gastrointestinalmotor function, 743

Somatostatin prevents the postoperative increases in plasma aminoacid clearance and urea synthesis after elective cholecystectomy,766

South Asia, South Asian and European colitics show characteristicdifferences in colonic mucus glycoprotein type and turnover, 696

Splanchnic blood flow, Why portal hypertensive varices bleed andbleed: a hypothesis, 100

SpleenHyposplenism in gastrointestinal disease: leading article, 165Preservation of the spleen improves survival after radical surgery for

gastric cancer, 684Splenectomy, Preservation of the spleen improves survival after radical

surgery for gastric cancer, 684Stents, stentingA three year follow up of selfexpanding metal stents in the endoscopic

palliation of longterm survivors with malignant biliary obstruction,618

Retained common bile duct stones after endoscopic sphincterotomy:temporary and longterm treatment with biliary stenting, 446

Role of biliary stenting in the management of bile duct stones in theelderly: leading article, 485

Stromelysin, Collagenase, stromelysin, and tissue inhibitor of metal-loproteinase expression in pancreatic and ampullary cancer, A477

Substrate metabolism, Energy expenditure and substrate metabolismin patients with cirrhosis of the liver: effects of the pattern of foodintake, 110

Super bone scan, A variant alkaline phosphatase found in a case ofgastric carcinoma with super bone scan, 299

Superantigen, Potential role of superantigen induced activation of cellmediated immune mechanisms in the pathogenesis of Crohn'sdisease: leading article, 1

Surgical emergencies, Surgical emergencies in tropical gastro-enterology: leading article, 9

T cells, Functional defect ofT cells in autoimmune gastritis, 171Technetium-99m, Quantification ofinflammatory bowel disease activity

using technetium-99m HMPAO labelled leucocyte single photonemission computerised tomography, 243

Volume 36: Subject index - Main headings

Test meal, Effect of a test meal on the intragastric distribution of urea inthe '3C-urea breath test for Helicobacter pylori, 337

Thrombelastography, Pharmacological manipulation of gastric juice:thrombelastographic assessment and implications for treatment ofgastrointestinal haemorrhage, 358

Thromboxanes, Misoprostol inhibits gastric mucosal release of endo-genous prostaglandin E2 and thromboxane B2 in healthy volunteers,511

Tissue factor, Tissue factor and tissue factor pathway inhibitor inhuman pancreatic carcinoma, A479

Transit, Differential regional effects of octreotide on human gastro-intestinal motor function, 743

Transport, Chloride dependent amino acid transport in the human smallintestine, 215

TuberculosisFulminant hepatic failure caused by tuberculosis, 792Increased CA 125 in a patient with tuberculous peritonitis: case report

and review of published works, 303Tuberculous peritonitis, Ascitic fluid gamma interferon concentrations

and adenosine deaminase activity in tuberculous peritonitis,419

Twins, P-ANCA in monozygotic twins with inflammatory boweldisease, 887

Tyrosine phosphorylation, Tyrosine phosphorylation in the humanduodenum, 34

Ulcerative colitisAn alternative view of 5-ASA formulations: correspondence, 639Cancer surveillance in ulcerative colitis: correspondence, 801Colonic epithelium is diffusely abnormal in ulcerative colitis and

colorectal cancer, 857DNA flow cytometric evaluation of cell cycle distribution in ulcerative

colitis: a proposed method for assessing severity of disease, 50Enhanced colonic nitric oxide generation and nitric oxide synthase

activity in ulcerative colitis and Crohn's disease, 718Inceased faecal mucin sulphatase activity in ulcerative colitis: a

potential target for treatment, 570New salicylates as maintenance treatment in ulcerative colitis: corre-

spondence, 640Preservation of complete anal sphincteric proprioception in restora-

tive proctocolectomy: the inhibitory reflex and fine control ofcontinence need not be impaired, 902

South Asian and European colitics show characteristic differences incolonic mucus glycoprotein type and turnover, 696

Urea breath test, High Helicobacter pylori numbers are associated withlow eradication rate after triple therapy, 845

Urea synthesis, Somatostatin prevents the postoperative increases inplasma amino acid clearance and urea synthesis after electivecholecystectomy, 766

Urinary tract infection, Natural history of bacteriuria in women withprimary biliary cirrhosis and the effect of antimicrobial therapy insymptomatic and asymptomatic groups, 931

Ursodeoxycholic acidCharacterisation of patients with a complete biochemical response to

ursodeoxycholic acid, 935Composition of gall bladder stones associated with octreotide:

response to oral ursodeoxycholic acid, 126

Vagal gastric acid secretion, Relation of acupuncture and vagal gastricacid secretion: correspondence, 800

Variceal bleeding, Recent advances in the endoscopic management ofvariceal bleeding: leading article, 647

Variceal haemorrhage, Why portal hypertensive varices bleed andbleed: a hypothesis, 100

Vascular regulation, Pancreatic vascular regulation in chronic pan-creatitis in cats, 133

Viraemia, Chronic hepatitis C virus infections: predictive value ofgenotype and level of viraemia on disease progression and responseto interferon a, 427

Viral hepatitis, Ecstasy induced hepatitis mimicking viral hepatitis,939

Vitamin D,. 1 ,25-dihydroxyvitamin D. and retinoid X receptor expres-sion in human colorectal neoplasms, 255

Wheat, Wheat deficient in gliadins: promising tool for treatment ofcoeliac disease, 375

Xanthine oxidase, Caffeine phenotyping of cytochrome P4501A2,N-acetyltransferase, and xanthine oxidase in patients with familialadenomatous polyposis, 251

Gut 1995; 36: 965-967

VOLUME 36: AUTHOR INDEX - SUPPLEMENT No 1

Abbasi AM, A17, A44Abraham H, A70Adams V, A52Addenbrooke's Hospital Transplant

Unit, A31Ahmed HA, AIO, A30Ahmed M, A44Ahmed MM, AlAhnen D, A5Al-Bloushi S, Al, A60AI-Mardini H, A31Alderson D, A29Alexander D, A40Alexander G, A31Alexander-Williams J, A25Allan PL, A20Allan RN, A25Allen A, A22, A51Allison MC, A22, A34Alstead EM, A4, A44Alvizi V, A42Amar S, A14Anderson JT, A34Andreyev HJN, A42Anggiansah A, A14, Al5Anthony A, A58, A59, A63Ardiles P, A57Ardill JES, A43Arendt G, A17Armitage NC, A22Armstrong G, A58, A60Armstrong JG, A43Arthur MJP, A38Asante MA, AlOAshworth A, A6Askew JN, A5Atherton JC, A59Auricchio S, A53Auwerda JJA, A16Axon ATR, AIO, A22, A24, A45,

A46, A49, A50, A51, A53Aziz Q, A65, A66

Badve S, All, A51Baeten CGMI, A68Bahl AK, A63Bain IM, A56Baird P, A30Ballinger AB, A4, A44Bancewicz J, A15, A65Banerjee S, A50Bansi DS, A18Bardhan KD, A22, A58Barham CP, A29Barlow J, A15, A65, A66Barlow JD, Al5Barnes E, A4Baron JH, Al1, A50Barrett DA, A21Barton R, A35Bartram CI, A16Bassendine MF, A38Bateson MC, A35Batt RM, A55Baxter ST, A14Beales ILP, A21, A45Beattie AD, A1OBeatty ER, A63Beck ER, A38Bedford F, A6Benatti P, A17Benghiat A, A37Benhattar J, A6Bennett DH, A23Benson RSP, A5Besbeas S, A23Beynon J, A29Bhargava A, A19, A32Binns J, A67Birt MC, A45Bishop A, A56Bjarnasson I, A70Blackshaw PE, A67Blakeston C, A12Bloom SR, A8Boerma MO, A16Boga E, A42Bond A, A20Borriello SP, A64Boulby P, A52Boulton RA, A21Bowling TE, A5, A8Bown SG, A28, A39, A41Bradley NJ, A19, A32Brady B, A36Bramley P, A20, A34Bramley PN, A13Branicki FJ, A28Brar A, A38

Brett P, A53Briel JW, A16British-Italian Gallstone Study

Group, A42Brown NJ, A58Brownlee KG, A51Brummer R-JM, A68Brunsden A, A9Buckels J, A61Burke DA, A45Burnham WR, A29Burnstock G, A29Burroughs AK, A19, A32, A60Bustin SA, A6Butterfield I, A48Bydder GM, A16Bzeizi KI, A33

Cakaloglu Y, A31Calam J, A8, A9, AIO, A21, A37,

A45, A50Callander N, A14Cameron AJ, A27Camm AJ, A12Canvin J, A63Capell HA, A54, A63Carli G, A70Carlotto C, A19Carpenter JC, A27Carrington D, A12Carswell N, A10Carter AM, A51Carter DC, A4, A40, A41Cassell TB, A47Castillo FD, A70Catto AJ, A51Cawkwell L, A6Cevallos AM, A26, A55Chadwick SJ, A42Chalmers DM, AIO, A50Chamberlain J, A23Chambers JB, A15Chambers S, A21Chan WC, A64Chapel H, A2Chapman P, A57Chapman RW, A18, A19Chapman RWG, Ai, A2Cheung W-Y, A33Chinery R, A58Chopra K, A4, A35Chowrimootoo GEF, A62Choy A, A28Christie J, A2Cicitira PJ, A53, A65Clancy T, A43Clark ML, A44Clarke PA, A22Clifford T, A18Cole AT, A49Collins JSA, A15, A65Collins T, A54Condez A, AlConio M, A39Conroy A, AlCook D, A28Cook G, A62Cooke RA, A15Coombs RC, A69Cooper BT, A54Cope C, A27Cotton PB, A4Cottrell J, A59Coulter L, A35Courtney MG, Al, A60Coutts GA, A37Covacci A, All, A45, A46Cowen SJ, A7Cox JGC, A68Coy DH, A48Crabtree JE, All, A45, A46, A49Crane RS, A70Crawford L, A26Crofton RW, A62Crowe JP, A22Cullen DJ, A59Cummings JH, A56, A63Cunningham D, A42

Dalla Libera M, A70Daszak P, A55Davidson B, A60Davidson BR, A19, A32Davies C, A41Davies DR, A43Davies G, A51Davies M, A38, A50Davies MK, A31

Day P, A65Day R, A44de Baat L, A39de Beaux AC, A4, A40, A41Deakin M, A36Debinski H, A39Deen K, A16Dees J, A39Deodhar KP, A61Desai DC, A61Desai ND, A61deSouza NM, A16, A37Dettmar PW, A22Devlin J, A3, A31, A60Dhillon AP, Al, A19, A32, A55,

A58, A59, A63Di Gregorio C, A6, A7Dick R, A26, A60Dickinson H, A33Dickson P, A22Diffey BL, A35Dillon JF, A32, A33Dixon MF, A6, AIO, A22, A50, A53Dockray GJ, A52Dodd C, A43Doig G, A68Domizio P, A13Donaldson P, A60Donnelly MT, A35, A36Douds AC, A20Dowling RH, A47, A56Doyle AP, A65Drake IM, AIO, A50Driscoll R, A25Drobniewski F, A64Drummond HE, A67Duggan AE, A12, A25Duncan HD, A36Dunn MRC, A56, A63Durdey P, A67Durridge M, A2Dusheiko GM, AlDuthie GS, A17, A18Dyson P, A45

Eastwood MA, A69El-Attar H, A16El-Nujumi A, Al1El-Omar E, Al1, A12, A43, A50Elias E, Al, A18, A38, A61Elliott LJ, A22Ellis AJ, A32Ellis HJ, A53, A65Ellis WR, A61Embaye H, A55Enck P, A17England AG, A38England RE, A4Ensari A, A53, A65Evans D, A14Evans DF, A70Evans DGR, A43Evans DH, A69Evans JA, A68Evans JMM, A24Evans RM, A62Evans T, A56Everitt N, A8Everitt NJ, A68Everitt SE, A34Eyre D, A46

Facer P, A56Fairclough PD, A4Fallowfield G, A30Fante R, A6, A7Farfan G, A36Farouk R, A17, A18Farthing MJG, A13, A26, A47, A54,

A55, A64, A66, A69Fasano A, A55Fearon KCH, A40, A41Featherstone J, A38Feighery C, A52Ferguson A, A7, A49, A67Ferguson J, A20Ferraris R, A42Fido RJ, A65Fielding G, A3, A36Fielding JF, Al, A60Filipowicz B, A59Finch M, A37Finlayson C, AIO, Al 1, AS 1Finlayson NDC, A33Fitt S, A32Fleming KA, A1, A2, A18, A19Flesch S, A17Fletcher JN, A55

Flett HI, A38Forbes A, A7, A17, A26, A44Forrest EH, A33, A61Fowler AL, A29Fozard B, A23Fracchia M, A42Francis H, A36Franklin IM, A62Fraser A, A13Fraser I, A43Fraser-Moodie C, A29Freeman JG, A37Freemont AJ, A2, A30Frieling T, A17Fukunaga Y, A15

Galloway SW, A42Gamberini S, A70Garden OJ, A37Garlick N, A49Garner A, A52Gazzard B, A23, A70Gazzard BG, A70Gee AS, A67Gee JM, A9Gemmell C, A2 1Gemmell CG, A63George DK, A62Getty B, A55Ghosh S, A7, A49, A67, A69Giaffer MH, A30Gibbons AH, A21, A37, A45, A50Gibson GR, A63Gibson H, A16Gifford K-A, A22Gilbert JA, A36Gillon KRW, A22Gimson AES, A4G.I.S.Co, A47Gleeson D, A30Goddard AF, A21Goddard CJR, A30Goddard M, A56Goldie AC, A41Goodlad RA, A5Goodman MJ, A58, A60Gornall CB, A29Gotley DC, A28Gould SR, A21Gowland P, A52Grant P, A51Greaves RRSH, A66Green J, A22, A34Green JRB, A36Greenfield SM, A38Greenway SC, A33Gregersen H, A15Griffin SM, A13, A27Griffith JP, A8, A43Grundman MJ, A35Gschmeissner S, A5Guandalini S, A55Gullini S, A66, A70Gummett PA, A50Gunn IR, A62Guy SP, A43Guz A, A61

Halder T, A30Halliday D, A12Hamdy S, A66Hamilton M, A57Hamilton MI, A26Hanby A, A5Hannan WJ, A7Hansford G, A26Hardcastle JD, A14, A22, A23Hardman K, A25Harkin M, A27Harris AW, All, A50Harris R, A43Harris S, A28Harrison RF, AlHart CA, A55Hatfield ARW, A5Haussinger D, A17Havard TJ, A13Hawkey CJ, A34, A49, A56, A57,

A59Hawkey GM, A34Hay FC, A20Haydon GH, A2Hayes G, A20Hayes PC, A2, A20, A32, A33, A61Healey CJ, Al, A2Heath DI, A40Heaton KW, A42Heaton ND, A32

965

Volume 36: Author index - Supplement No 1

Hebden JM, A66Henderson K, A6Henderson N, A32Hendrickse M, A30Heppell RM, A51Herd K, A34Heyer T, A17Heymann TD, A35Higgs NB, A48Higham AD, A52Hill K, A69Hillier V, A30Hobson A, A65, A66Hobson AR, A15Hodgkinson L, A36Hoefnagels JMJ, A68Holdsworth PJ, A24Holmes GKT, A29Holmes KT, A37Holmes S, A34Hopkins SJ, A48Homer K, A43Hossack M, A9Howard E, A3Howdle PD, A54Hoyland JA, A2, A30Hudson N, A59Hugh TJ, A45Hunt L, A30Hunter JO, A9, A10, A26, A56Hussain A, A68Hussain F, A28, A57Hussaini SH, A20, A47Hutchison GH, A28Huxham IM, AlOHyde S, A64

Idstrom J-P, A21Imrie CW, A40Innes JA, A61Interdisciplinary Group for the

Study of Cholelithiasis, A47Iqbal TH, A54Iredale JP, A38Irving MH, A48

Jackson P, A53Jacob S, A58Jacyna MR, A12, A50Jagger C, A3Jalan R, A20, A32, A33, A61James OFW, A38, A51Jankowski JA, A6Javle P, A33Jawhari A, A7, A26Jayne D, A57Jazrawi RP, A30, A42, A66Jenkins D, A49, A56Jenkins SA, A33, A38, A41Jessa MJ, A21Jewell DP, A24John TG, A37Johnson IT, A9Johnson JN, A28Johnson PRV, A3Johnston BT, A15Johnston D, A8, A24, A43Johnston DA, A34Jones AF, A63Jones AR, A14Jones E, A52Jordinson M, A8Joseph AEA, A64

Kalia N, A58Kamm MA, A26, A29Kane KF, A7Kapur K, A34Karani J, A37, A44Karat D, A13, A27Katelaris PH, A13Keighley MRB, A16, A25Kelly EJ, A51Kelly G, AlKelly MP, A54Kelly P, A55, A64Kenwright S, A46Keogh A, A18Kettlewell M, A24Kewenter J, A23Khakoo SI, AIKhulusi S, A10, All, A51Kim YS, A6King R, A43Kingsnorth AN, A38, A42Kirkland S, A6Kmiot W, A24Kmiot WA, A16Korsgen S, A16Kronborg 0, A23Krupkowicz D, A68Kuan AM, A38

Kubba AK, A46Kumar D, A56Kumar PJ, A36Kurtz J, Al, A2Kynaston HG, A33

Laing MW, A3Lane AJP, A69Langman MJS, A7Lansoprazole Study Group, A23Lanzini A, A42Larvin M, A40Leatham E, A12Lee CY, A5Lee FD, A21, A39, A54Lee JCW, A26Lee-Finglas W, A9Legon S, A45, A50Lennard-Jones JE, A26Leonard N, A52Levin RJ, A9, A69Levy J, A12Levy L, A46Lewin J, A55Lewis FA, A6Lewis KO, A54Lewis WG, A24LiD,A6Lim AG, All, A20, A30LinL,A13Lindley IJD, A49Linin J, AILipscomb GR, A40, A58, A60Lloyd DM, A3Lloyd R, A1l, A51Lobley R, A53Lockwood CM, A57Logan RFA, A12, A25, A34Lombard M, A4, A37, A39Lombard MG, A38Lomboy C, A27Long RG, A35, A36, A64Lora L, A19Losi L, A6, A7Losowsky MS, A20Loughrey G, A40Love AHG, AT5, A65Luo N, A54, A55, A64Lynch DAF, A22

McAlindon ME, A35McColl KEL, A9, All, A12, A43,

A50McCormick P, A60McDevitt DG, A24, A59MacDonald TM, A24, A59McDougall NI, A15, A65McFarland RJ, A15, A65MacFie J, A41McGarrity T, A5MacGilchrist AJ, A33McGilchrist MM, A24McGrath JS, A3McHugh M, A44McIntyre A, A67McIntyre AS, A35McKay IA, A6McKeegan EM, A44McKenzie J, A43MacKenzie JF, A39, A54, A62, A63McKnight G, A13, A34McLaughlan J, A49, A56Maclean KN, A6McLindon JP, A2McMahon AD, A24McMahon M, A40McMahon MJ, A8, A68McMahon RFT, A2, A30McOrist S, A56McPeake JR, A19McPhillips J, A39MacRobert AJ, A41McWhirter JP, A69Magnago IS, A29Mahida YR, A64Mahmood A, A41Mahmoud AEA, A61Mann CJ, A67Mann SG, A59Mapstone N, A1OMapstone NP, A50Mardon J, A46Marrero JM, A5 1Marsh MN, A53, A65Marshall K, A3Martin DF, A70Martin I, A6Martin IG, A8Martin JF, A19Martines D, A19Martins EB, A19Masson J, A13, A34Matthews P, A49

Maxwell JD, A20, A30, A64Maxwell-Armstrong C, A14May J, A8, A43Mazzon E, A19Mee AS, A23Mehan R, A16Mendall MA, A10, A11, A12, A51Menzies B, A28Menzies IS, A70Merighi A, A70Messman H, A39, A41Metivier E, A44Meulen JVD, A39Middleton SJ, A9, AIO, A56Middleton SM, A26Milanesi C, A19Millar B, A36Miller AS, A24Mills A, A29Mills C, A53Mills CO, A18Mills H, A16Milner P, A29Misiewicz JJ, A1l, ASOMistry R, A21Mitchell CJ, A41Mlkvy P, A39, A41Moayyedi P, A45, A46, A51, A53Mohamed R, A31Mokhashi M, A21Molineaux N, A12Molloy RG, A40Moloney M, A52Moncada S, A19Montgomery SM, A25Moore CM, A65Moran A, A49, A63Morant SV, A59Morgan AG, A46Morgan JM, A33Morgan S, A53Moriarty KJ, A16Morris A, A43Morris AJ, A39, A54, A63Morris D, A14Mortensen MJMcC, A24Moshakis V, A23Moss S, A23Moss SF, A9, AIOMourad FH, A47, A69Mowat A, A62Mowat NAG, A13, A34Mulla RJ, A21Muller AF, A36Mulroy A, A34Murchan P, A41Murphy G, A28Murphy GM, A47, A56Murphy J, A62Murray FE, A24, A34, A59Murray-Lyon IM, A35Mutimer DJ, AlMynott TL, A55

Naccarato R, A19, A47Naeem A, A26Nakshabendi IM, A21Nanivadekar SA, A61Naoumov NV, A32Nathanson L, A3, A28, A36Neal KR, A12, A25Nehra D, A29Neild P, A70Neild PJ, A70Nelufer JM, A53Neuberger JM, A31Newell SJ, A51Newton JL, A51Ng TM, A28, A39Ngwenya B, A55Nicholson DA, A40Nicolson V, A42Northfield TC, A10, A11, A12, A30,

A42, A51, A66Norton B, A29, A36Nunn E, A35

Oakley IG, A63Odedra RM, A55O'Donnell LJD, A66O'Farrelly C, A52O'Grady J, A20O'Hanlon DM, A13, A27Oldroyd B, A20Oliffe S, A61O'Mahony S, A53O'Morain CA, A22Ong C, A7Oppong K, A31O'Rourke K, A32O'Rourke N, A36O'Toole P, A39O'Toole PA, A4

Owen WA, A14Owen WJ, A14, AT5

Palmer J, A49Palmer KR, A4, A67Pankhurst C, A64Panos MZ, A63Papachrysostomou M, A49Parfrey NA, AlPark HS, A5Park RH, AIOParsons KF, A33Patch D, A60Patchett SE, A13Patel P, AT10, A1, A12, A51Paterson-Brown S, A37Pauer M, A39, A41Pazzi P, A42, A66, A70Peacock RA, A22Pearson GM, A34Pearson JP, A22, A51Peck N, A14Pedroni M, A6Peiffer LP, A5Penman ID, A43Penney LS, A54Pennington CR, A34, A69Pera M, A27Percesepe A, A17Pereira SP, A47, A56Perrett D, A47, A69Peters R, A4Peters RA, A37Petersen OH, A41Pethe VV, A61Petroni ML, A42, A66Phillips F, A69Phillips R, A39Phull PS, A12, A50Piasecki C, A63Piggozi G, A42Pignatelli M, A6, A24Piris J, A2Pitcher MCL, A56, A63Pittilo RM, A55Pittius C, A30Playford RJ, A5, A58Pobee JOM, A54, A55Podda M, A42Polak JM, A56Ponz de Leon M, A6, A7, A17Poon P, A41Portmann BC, A31, A32Poston GJ, A71Potter U, A54Poulter LW, AlPounder R, A57Pounder RE, A25, A26, A55, A58,

A59, A63Powell JJ, A48Preece P, A23Preston T, A9Price AB, A12Pugh S, A62Puni R, A16, A37Purcell M, A55Pye JK, A29

Quinn J, AIQuirke P, A6, A54

Raimes S, A13, A27Raimes SA, A45Ranganath L, A21Rankin BJ, A22Rappuoli R, A46Rate AJ, A15, A65Rathbone BJ, A3ReadS, Al, A2Record CO, A22, A31Redhead D, A61Redhead DN, A20, A32, A33Reed MWR, A58Rees D, A20Rees WDW, A40, A58, A60Regula J, A39Rela SM, A32Rembacken B, A49Reynolds PD, A26, A56Rhodes JM, A56Rhodes M, A3, A28, A36Ricci N, A70Richards J, A69Richards S, A43Riley S, A28, A57Rizzi PM, A44Robertson C, A14Robertson GSM, A3Robins A, A56Robinson E, A18Robinson GC, A59Robinson MR, A23

966

Volume 36: Author index - Supplement No I

Robinson NMK, A19Rodgers B, A2Rogers D, A67Rolles K, A19, A32, A60Roman F, A20Roncucci L, A6, A7, A17Rooney PS, A22Rose F, A64Rosen-Bronson S, A53Ross JA, A40, A41Rovins A, A49Rowan B, A30Rowbotham DS, A54Rowbottom A, A23Rowley JL, A23Rudd N, A44Russell RI, A21, A59, A63Ryder SD, A35, A44

Sachithanandan S, Al, A60Sagar PM, A24Samarasekera DN, A24Samways J, A61Sandle GI, A48Saraswat VA, A18Sargeant IR, A28Sargeant T, A27Sarsfield P, A13Saunders JR, A55Saunders S, A36Savage K, AlSaverymuttu SH, A64Sawant PD, A61Sawyerr AM, A69Sayer JM, A35Scagliarini R, A70Scapoli C, A17Schafer R, A17Schorah CJ, AIO, A50Schouten WR, A16Scott BB, A49, A56Scott D, A13Scott H, A24Scott-Mackie P, A42Sekaran C, A33Seth R, A49, A56Seymour CA, A12, A62Sharpstone D, A23, A70Shattock AG, AlShaw PN, A21SheafM, A26Sherman DIN, A25Shidrawi RG, A53Shield MJ, A59Shields R, A38Shorthouse M, A9, AIOSiersema PD, A39Sighinolfi D, A42Silk DBA, A8Sim R, A59Simmonds P, A2

Simpson M, A20Singh SD, A14Slater C, A9Sloan P, A43Smedley F, A36Smith A, A2, A30Smith GD, A67Smith HM, A32Smith J, A23Smith JA, A64Smith L, A28Smith MA, A20Smith N, A23Smith PM, A62Smith REA, A19Smithers BM, A28Snowdon N, A2Soediono PO, A29Solano J, A5Soni PN, AISoomoro I, A30Spencer GM, A28Spencer J, A24Spiegelman A, A39Spiller RC, A21, A52, A67Spittle MF, A5Spraggs CF, A63Srinivasan U, A52Srivastava ED, A22Stack WA, A57Stangou AJ, A3Stanley AJ, A2Stebbing JF, A24Steele RJC, A3, A14, A18Steer HW, A13Stellon AJ, A46Stewart SP, A20Stockbrugger RW, A68Strachan DP, A12Sturgess RP, A39Sturrock RD, A54, A63Sturrock RG, A59Sue-Ling HM, A8, A43Sutherland S, A31Sutton R, A14, A38, A41Swannell A, A59Swarbrick ET, A71

Tabaqchali S, A13Taha AS, A1O, A59Talbot IC, A17, A26, A44Tan CC, A37Tarnasky PR, A4Tatham AS, A65Taylor J, A35Thakker M, A40Thakker N, A43Thick M, A31Thomas HW, A32Thompson DG, A15, A48, A52,

A65, A66

Thompson M, A23Thompson NP, A25, A26Thompson RPH, A48Thorpe SM, A28Thrasivoulou C, A58Tighe MJ, A8Titley G, A34Tomkins DS, A22Torre F, A32Trastek VF, A27Treidosiewicz LK, A54Trevethick MA, A63Triger DR, A30Trudgill N, A28, A57Trye P, A59Turnbull AJ, A38Turvill JL, A47, A69

Underwood JCE, A30Usmani I, A12, A25

van Blankenstein M, A39van Schaick R, A71Vautier G, A49, A56Veitch AM, A54Veitch PS, A3Vellacott KD, A23Verma A, A30Vicary FR, A35, A38Volyanik EV, A6von Giesen HJ, A17Vyas SK, A38

Wadsworth MJ, A25Waghorn AJ, A24Wagner A, A53Wakefield AJ, A25, A26, A55, A57,

A58, A59, A63Walker MM, A1lWalker RJ, A38Walker SJ, A14, A71Wailer JM, A1lWallis N, A58, A60Wang J, A14Want SV, A21Ward JB, A41Wardle T, A53Warhurst AC, A48Warhurst G, A48Warland D, AIOWarnes TW, A2, A30, A43Wason C, A21Wass JAH, A47Watkins PE, A53Watson A, A14, A27Watson AJM, A5

Watson CJE, A31Watson J, A2Watson S, A18Weale AR, A29Webster GJM, A38Weir DG, A52Weldon MJ, A2 1, A64Wendon JA, A32Wessex Colorectal Cancer Audit

Working Group, A23West R, A61Westaby D, A4, A35, A37, A61White G, A24White KLM, A1O, A50Whitehead MW, A48Whyman MR, A46Wicks ACB, A3Wilde J, AlWilkinson LS, A42Wilkinson SP, A66Wilks M, A13Williams BC, A32Williams C, A9Williams GR, A7Williams GT, A22Williams JG, A33Williams NS, A6Williams R, A3, A19, A31, A32,

A44, A60WilliamsS, A4Williams SGJ, A37, A61Williamson MER, A24Wilson C, A40Wingate DL, A70Wirz A, All, A12, ASOWong C, A8Wong L, A43Wong S, A2Wong T, A60Wood C, A24Wood S,A7Woolley JA, A44Wortley GW, A9Wrangstadh M, A21Wright NA, A5, A6, A58Wright TA, A38Wyatt JI, All

Yapp T, A62Yates AD, A2Yates J, A33Yiannakou JY, A53Young S, A43Yuill R, A69

Zhang QB, A21Zhang ZW, A13Zhao MH, A57Zuin M, A42

967

Gut 1995; 36: 968-974

VOLUME 36: SUBJECT INDEX - SUPPLEMENT No 1

17-1A, Expression of CD44v6 and 17-lA in development and prognosisof colorectal cancer, A44

Abdominal computerised tomography, A prospective comparison ofabdominal computerised tomography and colonoscopy in thediagnosis of large bowel pathology in an elderly population, A40

Achalasia, Autonomic function in patients with achalasia and nut-cracker oesophagus, A28

Adhesion molecules, Expression of adhesion molecules in chronic liverallograft rejection, A19

Allograft rejectionExpression of adhesion molecules in chronic liver allograft rejection,A19

Importance of concomitant viral infection and treatment during lateacute liver allograft rejection, A31

Intercellular adhesion molecule-i as a predictor of liver allograftrejection, A32

Alpha-i antitrypsin, Validity of alpha-i antitrypsin as a test of entericprotein loss - upper gastrointestinal origins, A63

Ammonium, Effect of Helicobacter pylori on gastric mucosal ammoniumconcentrations, A9

Amoxicillin, Gastric ulcer recurrence following treatment withomeprazole and amoxicillin or omeprazole alone, A22

Anal fissure'Failed' lateral internal anal sphincterotomy for chronic anal fissure: a

study using endoanal ultrasound, A18Pathophysiological aspects and clinical outcome of intra-anal applica-

tion of isosorbide-di-nitrate in patients with chronic anal fissure,A16

Anal sphincterMagnetic resonance imaging of the anal sphincter using an endoanal

coil, A16Seepage of faeces is a marker of internal anal sphincter dysfunction,A67

Sensitivity and specificity of anal endosonography to detect analsphincter defects compared to EMG, A17

Anal sphincterotomy, 'Failed' lateral internal anal sphincterotomy forchronic anal fissure: a study using endoanal ultrasound, A18

Anastomotic leak, Self-expanding covered Giaturco stent preventstumour ingrowth in malignant dysphagia and seals anastomoticleak, A28

Angelchik prosthesis, Angelchik - the final nail? A14Anorexia, Circulating cytokines and anorexia in pancreatic cancer

patients, A44Antigen:antibody correlations, Antigen:antibody correlations in hepa-

titis C virus infection, A2Antimicrobial activity, Human terminal ileal mucosa expresses novel

antimicrobial activity, A64Antineutrophil cytoplasmic antibodies, Novel IgA antineutrophil

cytoplasmic antibodies against phospholipid targets in inflamma-tory bowel disease, A57

Antral gastric histoloty, Effect of omeprazole therapy on Helicobacterpylori, urease activity and antral gastric histology in patients withduodenal ulcer, A21

Antral intestinal metaplasia, Frequency of antral intestinal metaplasiaafter H. pylori eradication in duodenal ulcer patients, All

Apoptosis, Hydrogen peroxide induces apoptosis in HT-29 cells: aprocess which is not prevented by inhibition of poly-ADP-ribosepolymerase, A5

Appendicectomy, Appendicectomy, tonsillectomy and risk of inflam-matory bowel disease, A25

Arthritis, Jejunal bacteria in arthritis: important in pathogenesis ofdisease or development of NSAID enteropathy? A63

Artificial nutrition supports, Audit of the provision of artificial nutritionsupports, A69

Ascorbyl radical, The ascorbyl radical is increased in H. pyloriassociated gastritis, A50

Aspirin, Non-steroidal anti-inflammatory drugs, aspirin and colorectalcancer: a record-linkage case-control study, A24

Atrophic gastritis, Antibodies to CagA protein are associated withatrophic gastritis in H. pylori infection, A45

Audit, A33-35An audit of upper gastrointestinal haemorrhage: the effects of a

protocol and staff education, A34Audit of the provision of artificial nutrition supports, A69Auditing the audits of mortality from upper gastrointestinal haemor-

rhage: a plea for standardisation of methodology, A34H. pylori eradication for bleeding duodenal ulcer by non-

_gastroenterologists: an audit, A35Pitfalls in auditing upper gastrointestinal bleeding, A34Radical therapy for duodenal ulcer. Progress through audit, A35

Wessex colorectal cancer audit: colostomy rates following colon andrectal surgery, A23

What is the effect of setting up a nutrition team on the provision oftotal parenteral nutrition in a teaching hospital? A clinical audit,A36

Autoimmune hepatitis, Antineutrophil cytoplasmic antibody titre butnot IgG subclass distinguishes between primary sclerosingcholangitis and autoimmune hepatitis, A18

Autonomic function tests, Autonomic function tests in functionalbowel disorders, A66

Bactericidal/permeability-increasing protein, Bactericidal/permeability-increasing protein: a novel target antigen for P-ANCAin inflammatory bowel disease, A57

Barrett's oesophagusAdenocarcinoma of the oesophagogastric junction is associated with

Barrett's oesophagus, A27High incidence of Helicobacter pylori colonisation of Barrett's

oesophagus, A38Benign peptic strictures, Dilatation of benign peptic strictures, A71Benzalkonium chloride, Antral denervation by benzalkonium chloride

leads to gastric retention of solids in the rat, A52Beta3-adrenoceptor agonist, The B,-adrenoceptor agonist CL316243

prevents indomethacin-induced jejunal ulceration in the rat,A63

Bile canalicular membranes, Isolation of copper-binding proteins inbile canalicular membranes: a possible link to copper excretion andWilson's disease, A62

Bile duct stones, Endoscopic biliary endoprosthesis for the managementof bile duct stones in high risk groups, A4

Biliary tract, A3-5Bleeding units, Specialised bleeding units are the logical way forward in

the management of upper gastrointestinal haemorrhage, A34Body composition, Body composition at the bedside, A7Bone marrow transplantation, Iron overload in long term survivors of

bone marrow transplantation, A62Bowel, A prospective comparison of abdominal computerised tomo-

graphy and colonoscopy in the diagnosis of large bowel pathology inan elderly population, A40

Bowel disorders, Autonomic function tests in functional bowel dis-orders, A66

Bowel preparation, Bowel preparation at home - are the elderly beingput at risk? A35

Bran, Effect ofbran on colonic targeting of a novel drug delivery system,A67

Bromelain protease, Bromelain protease inhibits intestinal secretioncaused by Escherichia coli heat labile and heat stable toxins andVibrio cholerae cholera toxin, A55

Brush cytology, Brush cytology: a reliable method for detectingHelicobacter pylon gastric colonization, A70

Budd-Chiari syndrome, Mesocaval shunt versus radiological interven-tion in the treatment of Budd-Chiari syndrome, A61

Cadherins, Expression of cadherins (E and P), catenins (a and B) anddesmosome in normal and neoplastic human colorectal mucosa,A44

CagA expression, CagA expression is related to the severity of thepremalignant histological change in the stomach, A13

CagA proteinAntibodies to CagA protein are associated with atrophic gastritis inH. pylori infection, A45

Serological evaluationa of Helicobacter pylori eradication using recom-binant CagA protein, A46

CagA status, H. pylori-induced disturbance of gastric acid secretion isunrelated to bacterial CagA status, All

Calcium, A randomised trial of 1.5g calcium in patients with colorectaladenomata, A22

Calcium homeostasis, Disordered calcium homeostasis in experimentalpancreatitis, A41

Carbohydrates, The influence of non-digestible carbohydrates onenteroglucagon secretion and mucosal cell proliferation in the rat,A9

13Carbon urea breath test, Validation of a non-fasting `Carbon ureabreath test to diagnose Helicobacter pylori infection, A45

Carbopol 934P, Effect of carbopol 934P on the clinical course of activeulcerative colitis, A22

Cardiovascular risk factors, Association of Helicobacter pylori infectionwith coronary heart disease and cardiovascular risk factors, A12

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Volume 36: Subject index - Supplement No 1

Catenins, Expression of cadherins (E and P), catenins (a and B) anddesmosome in normal and neoplastic human colorectal mucosa,A44

CD44v6, Expression of CD44v6 and 17-lA in development andprognosis of colorectal cancer, A44

Celi adhesion molecules, Possible role of cell adhesion molecules intumour growth and metastasis, A17

Cell biology, A5-7Cholangiocarcinoma, Endoscopic stenting alone and stenting with

radiotherapy in non-resectable cholangiocarcinoma, ASCholecystectomy, Surgical intervention for symptomatic gallstone

disease - is there a relationship between preoperative symptoms andthe symptomatic outcome?, A3

Cholecystokinin, Lectins which bind N-acetylgalactosamine stimulatecholecystokinin release and pancreatic protein secretion in rats, A8

Cholera toxinComparison of small intestinal 5-HT release in secretory states

induced by cholera toxin and E. coli heat labile toxin, A47Correlation between duration of cholera toxin exposure and 5-HT

levels in small intestinal tissue and lumen, A47Small intestinal water movement in basal and cholera toxin induced

secretory states after 5-HT depletion, A69Cholestasis, Hypermanganesaemia and TPN: a cause of cholestasis? A7Cholyl-lysyl fluorescein, Uptake of cholyl-lysyl fluorescein by isolated

human hepatocytes, A18Cirrhosis

Differing actions of propranolol and nitrates in cirrhosis - a rationalefor combination therapy to prevent variceal haemorrhage? A61

Preliminary results of a randomised, controlled trial of TIPSS andvariceal band ligation in the prevention of variceal rebleeding incirrhosis, A33

CL316243, The B,-adrenoceptor agonist CL316243 preventsindomethacin-induced jejunal ulceration in the rat, A63

Cl- hypersecretion, Colonic electrogenic Cl- hypersecretion induced bystarvation: purative involvement of basolateral K+ conductance, A9

Clarithromycin, Patient factors that predict failure of omeprazole,clarithromycin and tinidazole to eradicate Helicobacter pylori, A46

Clinical trials, A21-23Clostridium difficile, The effects of C. difficile toxins A and B on the

accumulation of the second messenger inositol 1,4,5-triphosphatein membranes prepared from human duodenal biopsies, A64

Coagulation disorders, Management of hepatitis C virus infection inpatients with coagulation disorders, Al

Coeliac diseaseCoeliac disease: measurement of a toxic wheat peptide in gluten-free

foods, A65Detection of endomysial and reticulin antibodies in coeliac disease

using a single substrate: human umbilical cord, A53Differential binding of gluten peptides to HLA class II molecules

correlates with in vitro and in vivo toxicity in coeliac disease, A53Oats cereal is not toxic in coeliac disease, A52

Colchicine, Surrogate markers of response in a trial of ursodeoxycholicacid and colchicine in primary biliary cirrhosis, A30

ColitisDo patients with distal ulcerative colitis undergoing ileal pouch anal

anastomosis have a better outcome than those patients with totalcolitis? A24

Microscopic colitis: widening the definition, A26The small intestine in microscopic colitis: mucosal morphology,

permeability and secretory immunity to gliadin, A53Collagen production, The localisation of collagen production by in situ

hybridisation in primary biliary cirrhosis, A30ColonA specific role for sodium butyrate in growth arrest of colon cancer

cells, A6Crypt proliferation and reproduction in carcinogen or epidermal

growth factor treated rat colon, ASProperties of K' channels in K' secreting rat distal colon, A48Role of SSTR2 receptors in the antisecretory effect of somatostatin in

rat distal colon, A48Colonic targeting, Effect of bran on colonic targeting of a novel drug

delivery system, A67ColonoscopyA prospective comparison of abdominal computerised tomographyand colonoscopy in the diagnosis of large bowel pathology in anelderly population, A40

Is colonoscopy necessary as a first-line investigation in iron deficiencyanaemia? A35

Colorectal adenomata, A randomised trial of 1.5g calcium in patientswith colorectal adenomata, A22

Colorectal cancer, A23-249-cis retinoic acid differentially modifies vitamin D, action in twohuman colorectal cancer cell lines, A7

Colorectal cancer screening: the effect ofcombining flexible sigmoido-scopy with a faecal occult blood test, A23

Detection ofoccult nodal metastasis in patients with colorectal cancer,A43

Expression of cadherins (E and P), catenins (a and B) and desmosomein normal and neoplastic human colorectal mucosa, A44

Expression of CD44v6 and 17-lA in development and prognosis ofcolorectal cancer, A44

Frequency and type of transmission of hereditary non polyposiscolorectal cancer, A17

Gastrin and its precursors in human colorectal cancer, A43Inhibition of growth of human colorectal cancer by gastrin receptor

antagonism and the significance of gastrin receptor expression,A18

Microsatellite instability in sporadic colorectal cancer detected byfluorescent PCR, A6

Nuclear p53 overexpression in Dukes' stage B and colorectal cancer,A7

Qualitative and quantitative alterations of E-cadherin duringcolorectal tumorigenesis in vivo and in vitro, A6

Colorectal factors, A16-18, A23-27Colour flow Doppler ultrasonography, The role of duplex and colour

flow Doppler ultrasonography in the assessment of TIPSS shuntfunction, A20

Common bile duct exploration, Laparoscopic common bile ductexploration - lessons learned from 129 consecutive cases, A36

Copper-binding proteins, Isolation of copper-binding proteins in bilecanalicular membranes: a possible link to copper excretion andWilson's disease, A62

Coronary heart disease, Association of Helicobacterpylori infection withcoronary heart disease and cardiovascular risk factors, A12

Cortical swallowing pathways, Can magnetic stimulation of trigeminaland vagal nerve afferents be used to assess brainstem and corticalswallowing pathways? A66

Crohn's diseaseControlled study of outcome in ileal Crohn's disease: a comparison of

perforating and non-perforating indications for the initial resection,A25

Peripheral cell mediated immune response to mycobacteriae inCrohn's disease and controls, A54

Persistent measles virus infection in Crohn's disease: confirmation byimmunogold electron microscopy, A55

Cryotherapy, Cryotherapy and resection for advanced liver carcinoidtumour, A71

Crypt proliferation, Crypt proliferation and reproduction in carcinogenor epidermal growth factor treated rat colon, A5

Cryptosporidium parvum, Anti-Cryptosporidium parvum antibodyresponse in Zambian patients with HIV-related diarrhoea, A55

Crypts, K-ras mutations in human colonic aberrant crypts, A6Cyclosporin-A, Cyclosporin-A does not inhibit transcytotic vesicular

transport, A19Cyclosporine, Cyclosporine for the treatment of acute steroid resistant

ulcerative colitis, A57Cystic fibrosis, Pulmonary arteriovenous shunting in cystic fibrosis

patients with chronic liver disease may accelerate cardiopulmonarymortality, A61

CytokinesCirculating cytokines and anorexia in pancreatic cancer patients,A44

Cytokines, inflammation and hepatitis C infection, A2

Desk top reports, Desk top pictorial endoscopy reports, A39Desmosome, Expression of cadherins (E and P), catenins (a and B) and

desmosome in normal and neoplastic human colorectal mucosa,A44

Desulfovibrio spp, Desulfovibrio spp: an aetiological agent common toulcerative colitis and porcine proliferative enteropathy? A56

Diabetes, Screening for haemochromatosis in a diabetic clinic, A62Diarrhoea

Anti-Cryptosporidium parvum antibody response in Zambian patientswith HIV-related diarrhoea, ASS

Intestinal dysmotility in human immunodeficiency virus seropositivesubjects with diarrhoea, A70

Is diarrhoea complicating intragastric enteral feeding caused by anabnormal peptide YY response?, A8

Is tuberculous enteritis important in African slim disease? A64T-cell activation in the small intestinal mucosa of African AIDS

patients with chronic diarrhoea, A54Dilatation, Dilatation of benign peptic strictures, A71Distal oesophagus, Spectrum of bile acid reflux in gastro-oesophageal

reflux disease using a new device to sample the distal oesophagus,A29

Drinking, Drinking before endoscopy is safe, A38Drug delivery system, Effect of bran on colonic targeting ofa novel drug

delivery system, A67Duodenal gastric metaplasia

Relationship between H. pylori infection, inflammation and duodenalgastric metaplasia, All

The effect ofHelicobacterpylori eradication on gastric metaplasia in theduodenal bulb, All

969

970

Duodenal ulcerEffect ofomeprazole therapy on Helicobacter pylon, urease activity and

antral gastric histology in patients with duodenal ulcer, A21H. pylori eradication for bleeding duodenal ulcer by non-

gastroenterologists: an audit, A35Radical therapy for duodenal ulcer. Progress through audit, A35Recurrence of duodenal ulcer after Helicobacter pylori eradication is

related to high gastric acid output, A50Duodenal ulcer disease, Pathogenesis of gastric metaplasia in duodenal

ulcer disease, A51Dyspepsia

Effect of H. pylori eradication on the severity of dyspeptic symptomsin DU patients, A12

H. pylon infection and dyspepsia within the general population, A50Is absence of dyspeptic symptoms a useful test to assess H. pylori

eradication? A12Dysphagia

Intraluminal radiotherapy for the palliation of dysphagia in patientswith inoperable carcinoma of the proximal stomach, A45

Self-expanding covered Giaturco stent prevents tumour ingrowth inmalignant dysphagia and seals anastomotic leak, A28

E-cadherin, Qualitative and quantitative alterations of E-cadherinduring colorectal tumorigenesis in vivo and in vitro, A6

Echo planar imaging, Use of echo planar imaging to assess effect ofposture on intragastric distribution of lipid and gastric emptying,A52

Echogenic bile, Echogenic bile - what is the significance? A42Electron energy loss spectroscopy, Assessment of gastric mucosal and

mucus layer elemental trace metals in H. pylori gastritis using thenovel technique of electron energy loss spectroscopy, AIO

Endoanal coil, Magnetic resonance imaging of the anal sphincter usingan endoanal coil, A16

Endoluminal ultrasonography, Endoluminal ultrasonography in stag-ing of oesophageal cancer - the influence of endoscopic dilatation,A27

Endomysial antibodies, Detection of endomysial and reticulin anti-bodies in coeliac disease using a single substrate: human umbilicalcord, A53

Endopeptidase 24:11, Intestinal expression and activity of neutralendopeptidase 24:11 in man, A49

Endoprosthesis, Endoscopic biliary endoprosthesis for the managementof bile duct stones in high risk groups, A4

Endoscopy, A37-40Efficacy of percutaneous endoscopic gastrostomy versus nasogastric

tube in enteral nutrition, A68Enteral feeding, Effect of enteral feeding on post natal splanchnic

haemodynamics in human preterm neonates, A69Enteroglucagon, The influence of non-digestible carbohydrates on

enteroglucagon secretion and mucosal cell proliferation in the rat,A9

Epidermal growth factorCrypt proliferation and reproduction in carcinogen or epidermal

growth factor treated rat colon, A5Distribution of the EGF-receptor in the normal human gastrointesti-

nal tract, A5The ontogenic role of EGF in the developing human stomach,A51

ERCPCriteria for ERCP in the laparoscopic era, A3Diagnostic and therapeutic ERCP on outpatients - is it safe and cost

effective? A36ERCP-related pancreatitis, ERCP-related pancreatitis: the danger of

leaving an obstructed biliary system, A4Escherichia coli

Bromelain protease inhibits intestinal secretion caused by Escherichiacoli heat labile and heat stable toxins and Vibrio cholerae choleratoxin, A55

P-fimbriated Escherichia coli adhere to differentiated intestinal epithe-lial cells (Caco-2) and stimulate production of interleukin-8, A55

Faecal incontinence, Long term results of total pelvic floor repair forneuropathic faecal incontinence, A16

Faecal pancreatic elastase 1, Faecal pancreatic elastase 1 assay as adiagnostic test for chronic pancreatitis, A41

Familial adenomatous polyposis, Photodynamic therapy for the endo-scopic treatment of polyps in familial adenomatous polyposis, A39

Famotidine, High dose famotidine for healing and subsequent mainte-nance in non-steroidal anti-inflammatory drug-associated gastro-duodenal ulceration, A59

Fibrosis, Detection of insulin-like growth factor 1 in whole gut lavagefluid: a novel method of studying intestinal fibrosis, A49

5-Fluorouracil, Infusional 5-fluorouracil with interferon is well toler-ated and provides useful palliation in patients with symptomaticmalignant neuroendocrine tumours, A42

Volume 36: Subject index - Supplement No I

Follicular gastritis, The incidence and severity of follicular gastritis incases of gastric carcinoma, A13

FundoplicationLaparoscopic Nissen fundoplication - lessons learned from 200

consecutive cases, A28Randomised controlled trial of Nissen versus Lind fundoplication:

results at ten year follow-up, A14

Gallbladder, Prostaglandins contract and relax human gallbladder invitro, A66

Gallbladder motility, Role of gallbladder motility defects in patho-genesis of gallstone recurrence, A66

GallstonesBiliary phospholipids and mucin glycoprotein are altered in

octreotide-induced gallstones, A47Efficacy ofursodeoxycholic acid alone and with chenodeoxycholic acid

for cholesterol gallstone dissolution, A42Role of gallbladder motility defects in pathogenesis of gallstone

recurrence, A66TUDCA treatment of gallstones in patients at high risk for surgery,A47

Gardner's syndrome, Severe Gardner's syndrome in families withmutations restricted to a specific region of the APC gene, A43

Gastric acid output, Recurrence of duodenal ulcer after Helicobacterpylori eradication is related to high gastric acid output, A50

Gastric acid secretion, H. pylorn-induced disturbance of gastric acidsecretion is unrelated to bacterial CagA status, All

Gastric cancerAdjuvant mitomycin C after radical surgery for gastric cancer: effecton cell mediated immunity, A43

Intraluminal radiotherapy for the palliation of dysphagia in patientswith inoperable carcinoma of the proximal stomach, A45

Lack of a simple explanation for gastric tumours induced by H2antagonists in rats, A52

Gastric carcinoma, The incidence and severity of follicular gastritis incases of gastric carcinoma, A13

Gastric emptying, Use of echo planar imaging to assess effect of postureon intragastric distribution of lipid and gastric emptying, A52

Gastric juice, Effect of omeprazole on the distribution of antibiotics ingastric juice, A21

Gastric lymphoma, Is Helicobacter pylori infection of any significance inthe aetiology of primary gastric lymphoma? A13

Gastric metaplasia, Pathogenesis ofgastric metaplasia in duodenal ulcerdisease, A51

Gastric ulcer, Gastric ulcer recurrence following treatment withomeprazole and amoxicillin or omeprazole alone, A22

Gastric ulcer formation, AS8-60Gastrin, Gastrin and its precursors in human colorectal cancer, A43Gastrin mRNA, Changes in the expression of somatostatin and gastrin

mRNA in response to gastrin releasing peptide are altered byH. pylon infection, AS0

Gastrin receptor, Inhibition of growth of human colorectal cancer bygastrin receptor antagonism and the significance of gastrin receptorexpression, A18

Gastritis, The ascorbyl radical is increased in H. pylon associatedgastritis, ASO

Gastro-oesophageal malignancy, Laparoscopic ultrasonography in thestaging of gastro-oesophageal malignancy, A37

Gastro-oesophageal refluxCauses of failure to respond to omeprazole in 44 patients with gastro-

oesophageal reflux symptoms, A14Effect of weight loss of symptoms of gastro-oesophageal reflux,A29

Is laparoscopic fundoplication a more attractive option than long-termomeprazole in gastro-oesophageal reflux disease? A14

Spectrum of bile acid reflux in gastro-oesophageal reflux disease usinga new device to sample the distal oesophagus, A29

Gastroenterology, Providing an effective clinical service in gastro-enterology: the value of information, A33

General practice, Open access gastroscopy in general practice: sevenmonths experience, A38

Giaturco stent, Self-expanding covered Giaturco stent prevents tumouringrowth in malignant dysphagia and seals anastomotic leak, A28

GliadinIn vivo activity of peptides 31-43, 44-55, 56-68 of ea-gliadin in gluten

sensitive enteropathy, A53Rectal challenge with highly purified omega-gliadin identifies the

repeat octapeptide PQQPFPQQ as an immunopathological moietyin gluten sensitized subjects, A65

The small intestine in microscopic colitis: mucosal morphology,permeability and secretory immunity to gliadin, A53

GlutamineDoes the addition of glutamine to intravenous nutrition preventimmunosuppression following major surgery? A8

Oral glutamine challenge in cirrhotics awaiting liver transplantation: apsychometric and analysed EEG study, A31

Volume 36: Subject index - Supplement No 1

GlutenCoeliac disease: measurement of a toxic wheat peptide in gluten-free

foods, A65Differential binding of gluten peptides to HLA class II molecules

correlates with in vitro and in vivo toxicity in coeliac disease, A53Rectal challenge with highly purified omega-gliadin identifies the

repeat octapeptide PQQPFPQQ as an immunopathological moietyin gluten sensitized subjects, A65

Gluten sensitive enteropathy, In vivo activity of peptides 31-43, 44-55,56-68 of et-gliadin in gluten sensitive enteropathy, A53

Glyceryl trinitrate, Glyceryl trinitrate does not reduce thrombophlebitisduring full intravenous nutrition through a peripheral vein, A8

Glycoprotein, Biliary phospholipids and mucin glycoprotein are alteredin octreotide-induced gallstones, A47

Glycosylation profile, Immunoglobulin G glycosylation profile inchronic liver diseases, A20

GROa, Inflammatory stimuli activate secretion of IL-8 and GROat butnot RANTES in human colonic epithelial cells in vitro, A48

H2 antagonists, Lack of a simple explanation for gastric tumoursinduced by H2 antagonists in rats, A52

Haemochromatosis, Screening for haemochromatosis in a diabeticclinic, A62

Helicobacter pylori, A9-13A new short, highly effective Helicobacter pylori eradication regime, A21A randomised trial of 3 eradication regimes for Helicobacter pylori, A21Antibodies to CagA protein are associated with atrophic gastritis inH. pylori infection, A45

Brush cytology: a reliable method for detecting Helicobacter pylorigastric colonization, A70

Changes in the expression of somatostatin and gastrin mRNA inresponse to gastrin releasing peptide are altered by H. pyloriinfection, A50

Effect ofomeprazole therapy on Helicobacterpylori, urease activity andantral gastric histology in patients with duodenal ulcer, A21

H. pylori eradication for bleeding duodenal ulcer by non-gastroenterologists: an audit, A35

H. pylori infection and dyspepsia within the general population, A50Helicobacter pylori does not influence gastric mucosal adaptation toNSAIDs in man, A60

High incidence of Helicobacter pyloai colonisation of Barrett'soesophagus, A38

Patient factors that predict failure of omeprazole, clarithromycin andtinidazole to eradicate Helicobacter pylon, A46

Recurrence of duodenal ulcer after Helicobacter pylor eradication isrelated to high gastric acid output, A50

Serological evaluationa of Helicobacter pylon eradication using recom-binant CagA protein, A46

The ascorbyl radical is increased in H. pylori associated gastritis, A50The effect of H. pylori infection on the expression of somatostatinmRNA in the gastric antrum and corpus, A45

Validation of a non-fasting `3carbon urea breath test to diagnoseHelicobacter pylori infection, A45

Validation of a rapid whole blood test for the diagnosis of Helicobacterpylori infection, A51

Hepatectomy, Hepatectomy in the management of critically ill patientswith acute liver failure, A32

Hepatic failure, Induction of nitric oxide synthase in the hepatic arteryduring hepatic failure in man, A19

Hepatitis, Long-term follow-up of chronic active hepatitis in Wales:results of a close-control treatment regimen, A62

Hepatitis B virus, Treatment of hepatitis B virus recurrence in livertransplant recipients, A32

Hepatitis C, A1-2Hepatitis C virus, Intrafamilial transmission of anti-D associated

Hepatitis C virus - a zero risk? A60Hepatoceliular carcinoma, Chemoembolization for hepatocellular car-

cinoma: applicability and response in British patients, A44Hepatocytes, Uptake of cholyl-lysyl fluorescein by isolated human

hepatocytes, A18Hepatorenal reflex, Role of neuro humoral factors in the mediation of

the "hepatorenal reflex", A33Hilar strictures, The management of high grade hilar strictures by the

endoscopic insertion of self-expanding metal endoprostheses, A37HIV

Anti-Cryptosponidium parvum antibody response in Zambian patientswith HIV-related diarrhoea, A55

Intestinal dysmotility in human immunodeficiency virus seropositivesubjects with diarrhoea, A70

Small bowel transit in HIV-seropositive individuals, A70HT-29 cells, Hydrogen peroxide induces apoptosis in HT-29 cells: a

process which is not prevented by inhibition of poly-ADP-ribosepolymerase, A5

Hydrogen peroxide, Hydrogen peroxide induces apoptosis in HT-29cells: a process which is not prevented by inhibition of poly-ADP-ribose polymerase, A5

971

Hydrophobicity, Gastric mucosal hydrophobicity and H. pyloriinfection density: a mechanism for peptic ulcer pathogenesis?A10

5-HydroxytryptamineComparison of small intestinal 5-HT release in secretory states

induced by cholera toxin and E. coli heat labile toxin, A47Correlation between duration of cholera toxin exposure and 5-HT

levels in small intestinal tissue and lumen, A47Small intestinal water movement in basal and cholera toxin induced

secretory states after 5-HT depletion, A69Hypermanganesaemia, Hypermanganesaemia and TPN: a cause of

cholestasis?, A7

Ibuprofen, Acute gastric tolerability of S(+) ibuprofen compared toracemic ibuprofen, A59

IgM anti-HCV testing, IgM-HCV testing may reduce need for PCRtesting, Al

Immunosuppression, Does the addition of glutamine to intravenousnutrition prevent immunosuppression following major surgery?,A8

In situ hybridisation, The localisation of collagen production by in situhybridisation in primary biliary cirrhosis, A30

IndomethacinAntral and corpus indomethacin-induced gastric ulceration is depen-

dent on the distribution of mucosal contractile cells, A59Combined intestinal trefoil factor and epidermal growth factor is

prophylactic against indomethacin induced gastric damage in therat, A58

Indomethacin-induced jejunal villous contraction and microvascularocclusion, A58

The B3-adrenoceptor agonist CL316243 prevents indomethacin-induced jejunal ulceration in the rat, A63

Inflammation, Cytokines, inflammation and hepatitis C infection,A2

Inflammatory bowel diseaseAdequacy of information and concerns of patients with juvenile onsetIBD, A67

Anti-epithelial cell antibodies in familial inflammatory bowel diseaseand their relatives, A26

Appendicectomy, tonsillectomy and risk of inflammatory boweldisease, A25

Bactericidal/permeability-increasing protein: a novel target antigenfor P-ANCA in inflammatory bowel disease, A57

Biliary lactoferrin concentrations are increased in active inflammatorybowel disease: a factor in the pathogenesis of primary sclerosingcholangitis? A56

Childhood domestic hygiene, Helicobacter pyloni infection and inflam-matory bowel disease: is there an association? A12

Correlation between interleukin-8, interferon-gamma, interleukin-10mRNA levels and histological activity in inflammatory boweldisease, A49

Early determinants ofinflammatory bowel disease: use of two nationallongitudinal birth cohorts, A25

Genetics vs environment in inflammatory bowel disease: concordancerates in 130 twin pairs, A25

Novel IgA antineutrophil cytoplasmic antibodies against phospho-lipid targets in inflammatory bowel disease, A57

Psychological morbidity in inflammatory bowel disease - a case forpsychological counselling? A67

Sex differences in the health locus of control and learned illnessbehaviour in patients with the irritable bowel syndrome andinflammatory bowel disease, A16

Information, Providing an effective clinical service in gastroenterology:the value of information, A33

Injection sclerotherapy, Multicentre trial of octreotide versus injectionsclerotherapy for acute variceal haemorrhage, A38

Insulin-like growth factor, Detection of insulin-like growth factor 1 inwhole gut lavage fluid: a novel method of studying intestinalfibrosis, A49

Interferon, Infusional 5-fluorouracil with interferon is well tolerated andprovides useful palliation in patients with symptomatic malignantneuroendocrine tumours, A42

Interferon alphaHepatitis C infection and alpha-interferon therapy in patients with_normal transaminases, Al

Treatment of acute hepatitis C with alpha interferon in hypogam-maglobulinaemia. The UK Gammagard outbreak, A2

Interferon-gammaCorrelation between interleukin-8, interferon-gamma, interleukin-10mRNA levels and histological activity in inflammatory boweldisease, A49

Production of interferon-gamma by liver and peripheral bloodT-lymphocytes in primary sclerosing cholangitis, A19

Interleukin-6, Induction of prostaglandin mediated regulation of bloodmononuclear cell interleukin-6 release in patients with acutepancreatitis, A40

Volume 36: Subject index - Supplement No I

Interleukin-8Bacterial lipopolysaccharide stimulates interleukin-8 secretion from

colonic cell lines, A49Inflammatory stimuli activate secretion of IL-8 and GROca but notRANTES in human colonic epithelial cells in vitro, A48

P-fimbriated Escherichia coli adhere to differentiated intestinalepithelial cells (Caco-2) and stimulate production of interleukin-8,A55

Use of a new enzyme linked PCR assay to show increased induciblenitric oxide synthase and interleukin 8 mRNA in ulcerative colitis,A56

Interleukins, Correlation between interleukin-8, interferon-gamma,interleukin-10 mRNA levels and histological activity in inflamma-tory bowel disease, A49

Intestinal trefoil factor, Combined intestinal trefoil factor and epider-mal growth factor is prophylactic against indomethacin inducedgastric damage in the rat, A58

Intra-abdominal abscess, Comparison of 99m technetium-HMPAOlabelled leucocyte with 111-indium labelled granulocyte scanningand ultrasound in the diagnosis of intra-abdominal abscess, A64

Intraluminal oesophageal distension, Oesophageal wall tension notdistension pressure or volme determines sensation in man, A15

Intraluminal radiotherapy, Intraluminal radiotherapy for the palliationof dysphagia in patients with inoperable carcinoma of the proximalstomach, A45

Intravenous nutritionThe basilic is the vein of choice for peripheral infusion of intravenous

nutrition, A68Thrombophlebitis is established before occlusion of the vein occurs

during infusion of intravenous nutrition, A68Iron, Iron overload in long term survivors of bone marrow transplanta-

tion, A62Iron deficiency, Iron deficiency in general practice, A46Iron deficiency anaemia, Is colonoscopy necessary as a first-line

investigation in iron deficiency anaemia? A35Irritable bowel syndrome, Sex differences in the health locus of control

and learned illness behaviour in patients with the irritable bowelsyndrome and inflammatory bowel disease, A16

Isosorbide-di-nitrate, Pathophysiological aspects and clinical outcomeof intra-anal application of isosorbide-di-nitrate in patients withchronic anal fissure, A16

Jaundice, Will laparoscopic biliary bypass replace endoscopic stentingfor malignant obstructive jaundice? A4

Jejunal bacteria, Jejunal bacteria in arthritis: important in pathogenesisof disease or development ofNSAID enteropathy? A63

Jejunal biopsy, Small bowel enteroscopy: should jejunal biopsy beroutine? A39

Jejunal lesions, Jejunal lesions in human non-steroidal anti-inflammatory drug enteropathy, A54

Jejunal ulcerationAntral and corpus indomethacin-induced gastric ulceration is depen-

dent on the distribution of mucosal contractile cells, A59The B3-adrenoceptor agonist CL316243 prevents indomethacin-

induced jejunal ulceration in the rat, A63Jejunal villous contraction, Indomethacin-induced jejunal villous con-

traction and microvascular occlusion, A58

K+ channels, Properties of K' channels in K+ secreting rat distal colon,A48

K-ras mutations, K-ras mutations in human colonic aberrant crypts, A6

Lactase, Small intestinal lactase status, frequency distribution ofenzyme activity and milk intake in west Birmingham, A54

Lactoferrin, Biliary lactoferrin concentrations are increased in activeinflammatory bowel disease: a factor in the pathogenesis of primarysclerosing cholangitis? A56

Lansoprazole, Lansoprazole provides greater symptom relief thanomeprazole in reflux oesophagitis, A23

Laparoscopic biliary bypass, Will laparoscopic biliary bypass replaceendoscopic stenting for malignant obstructive jaundice? A4

Laparoscopic biliary and gastric bypass, Laparoscopic biliary andgastric bypass - a useful adjunct in the management of carcinoma ofthe pancreas, A3

Laparoscopic cholecystectomy, Laparoscopic common bile ductexploration - lessons learned from 129 consecutive cases, A36

Laparoscopic ultrasonography, Laparoscopic ultrasonography in thestaging of gastro-oesophageal malignancy, A37

Laparoscopy, Local recurrence after standard and laparoscopicallyassisted excision of colorectal carcinomas, A24

Laser treatment, Prospective randomised trial of laser treatment versuslaser followed by brachytherapy for palliation of oesophagealcarcinoma (preliminary report), A37

Laxatives, Do we use laxatives rationally in hospital in-patients? A36

Lectins, Lectins which bind N-acetylgalactosamine stimulatecholecystokinin release and pancreatic protein secretion in rats,A8

Lipids, Use of echo planar imaging to assess effect of posture onintragastric distribution of lipid and gastric emptying, A52

Lipopolysaccharide, Bacterial lipopolysaccharide stimulates inter-leukin-8 secretion from colonic cell lines, A49

Liver, A18-20, A30-33, A60-62Liver carcinoid tumour, Cryotherapy and resection for advanced liver

carcinoid tumour, A71Liver failure

Alterations in hepatic haemodynamics may contribute to the abnor-malities in renal blood flow in liver failure, A33

Hepatectomy in the management of critically ill patients with acuteliver failure, A32

Liver transplantationImportance of concomitant viral infection and treatment during late

acute liver allograft rejection, A31Intercellular adhesion molecule-l as a predictor of liver allograft

rejection, A32Liver transplantation for the over sixties? A31Oral glutamine challenge in cirrhotics awaiting liver transplantation: a

psychometric and analysed EEG study, A31Osteopenia after liver transplantation: an over-estimated risk? A20QT interval prolongation and autonomic dysfunction in endstage liver

disease: effect of liver transplantation, A31Repeat HLA mismatches improve survival after second liver trans-

plantation, A60TIPS transplantation and surgical shunts, A60Treatment of hepatitis B virus recurrence in liver transplant

recipients, A32Lymphocytes, Lymphocyte phenotypes in chronic hepatitis C infec-

tion: a correlation with disease activity, AlLymphoma, Is Helicobacter pylori infection of any significance in the

aetiology of primary gastric lymphoma? A13

Magnetic resonance imagingEndoscopic magnetic resonance imaging of the oesophagus using a

dedicated surface receive coil, A37Magnetic resonance imaging of the anal sphincter using an endoanal

coil, A16Mallory-Weiss tear, Mallory-Weiss revisited, A13Manometry

24-hour manometry is essential to diagnose diffuse oesophagealspasm, A29

Oesophageal motility disorders should be classified on the basis ofabnormal neurophysiology rather than manometry, A65

Measles virus infection, Persistent measles virus infection in Crohn'sdisease: confirmation by immunogold electron microscopy, A55

Mesalazine, A pharmacokinetic study of single and divided dosedelayed-release mesalazine, A57

Mesocaval shunt, Mesocaval shunt versus radiological intervention inthe treatment of Budd-Chiari syndrome, A61

Metal absorption, The gut mucus layer regulates metal absorption? A48Metatetrahydroxyphenylchlorin, Photodynamic therapy for cancer in

the hamster pancreas using metatetrahydroxyphenylchlorin, A41Methotrexate, Low-dose methotrexate in treatment of primary biliary

cirrhosis, A30Microcirculation, The role of gastric mucosal microcirculation in ulcer

formation, A58Microsatellite instability, Microsatellite instability in sporadic colorec-

tal cancer detected by fluorescent PCR, A6Microscopic colitis, The small intestine in microscopic colitis:

mucosal morphology, permeability and secretory immunity togliadin, A53

Microsporidiosis, The treatment of microsporidiosis with thalidomide,A23

Microvascular occlusion, Indomethacin-induced jejunal villous con-traction and microvascular occlusion, A58

Mitomycin C, Adjuvant mitomycin C after radical surgery for gastriccancer: effect on cell mediated immunity, A43

Motility disorders, The natural history of primary oesophageal motilitydisorders, A15

Mucosal celis proliferation, The influence of non-digestible carbo-hydrates on enteroglucagon secretion and mucosal cell proliferationin the rat, A9

Mucosal neurotransmitters, Changes in mucosal neurotransmitters inpatients with reflux oesophagitis, A29

Neuroendocrine tumours, Infusional 5-fluorouracil with interferon iswell tolerated and provides useful palliation in patients withsymptomatic malignant neuroendocrine tumours, A42

Nitrates, Differing actions of propranolol and nitrates in cirrhosis - arationale for combination therapy to prevent variceal haemorrhage?A61

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Volume 36: Subject index - Supplement No 1

Nitric oxide synthaseHigh expression of iNOS in colonic mucosa in ulcerative colitis,A56

Induction of nitric oxide synthase in the hepatic artery during hepaticfailure in man, A19

Is gastric mucosal nitric oxide synthase activity increased in patientswith H. pylon associated duodenal ulceration?, AIO

Use of a new enzyme linked PCR assay to show increased induciblenitric oxide synthase and interleukin 8 mRNA in ulcerative colitis,A56

Non cardiac chest pain, Hyperventilation and oesophageal dysmotilityin patients with non cardiac chest pain, A15

Non-steroidal anti-inflammatory drugs, A58-60Jejunal bacteria in arthritis: important in pathogenesis of disease or

development of NSAID enteropathy? A63Jejunal lesions in human non-steroidal anti-inflammatory drug entero-

pathy, A54Non-steroidal anti-inflammatory drugs, aspirin and colorectal cancer:

a record-linkage case-control study, A24Nurse practitioners, Endoscopy nurse practitioners: prospective

evaluation as first assistant at PEG tube insertion, A39Nutcracker oesophagus, Autonomic function in patients with achalasia

and nutcracker oesophagus, A28Nutrition, A7-A9, A68-70Nutrition team, What is the effect of setting up a nutrition team on the

provision of total parenteral nutrition in a teaching hospital? Aclinical audit, A36

Oats cereal, Oats cereal is not toxic in coeliac disease, A52Octreotide, Multicentre trial ofoctreotide versus injection sclerotherapy

for acute variceal haemorrhage, A38Octreotide-induced galistones, Biliary phospholipids and mucin

glycoprotein are altered in octreotide-induced gallstones, A47Oesophageal cancer

Endoluminal ultrasonography in staging of oesophageal cancer - theinfluence of endoscopic dilatation, A27

Management of strictures after radiotherapy for treatment ofoesophageal cancer, A28

Quality life assessment is an important tool in measuring outcome inpatients undergoing treatment for carcinoma of the oesophagus,A27

Oesophageal carcinoma, Prospective randomised trial of laser treat-ment versus laser followed by brachytherapy for palliation ofoesophageal carcinoma (preliminary report), A37

Oesophageal motilityDoes healing of oesophagitis improve ambulatory oesophageal

motility and pH profile? A65Oesophageal motility disorders should be classified on the basis of

abnormal neurophysiology rather than manometry, A65Oesophagitis

Does healing of oesophagitis improve ambulatory oesophagealmotility and pH profile? A65

Three year follow-up of oesophagitis with endoscopy and oesophagealpH monitoring, A15

Oesophagus, A13-15, A27-29Endoscopic magnetic resonance imaging of the oesophagus using a

dedicated surface receive coil, A37Omeprazole

Causes of failure to respond to omeprazole in 44 patients with gastro-oesophageal reflux symptoms, A14

Effect of omeprazole on the distribution of antibiotics in gastric juice,A21

Effect ofomeprazole therapy on Helicobacter pylori, urease activity andantral gastric histology in patients with duodenal ulcer, A21

Gastric ulcer recurrence following treatment with omeprazole andamoxicillin or omeprazole alone, A22

Is laparoscopic fundoplication a more attractive option than long-termomeprazole in gastro-oesophageal reflux disease? A14

Lansoprazole provides greater symptom relief than omeprazole inreflux oesophagitis, A23

Patient factors that predict failure of omeprazole, clarithromycin andtinidazole to eradicate Helicobacter pylori, A46

Open access gastroscopy, Open access gastroscopy in general practice:seven months experience, A38

Osteopenia, Osteopenia after liver transplantation: an over-estimatedrisk? A20

p53 overexpression, Nuclear p53 overexpression in Dukes' stage B andcolorectal cancer, A7

Pain, Is common bile duct dysmotility a common cause of post-cholecystectomy biliary pain?, A3

Pancreatic cancer, Circulating cytokines and anorexia in pancreaticcancer patients, A44

Pancreatic carcinoma, Laparoscopic biliary and gastric bypass - auseful adjunct in the management of carcinoma of the pancreas, A3

Pancreatitis, A40-42ERCP-related pancreatitis: the danger of leaving an obstructed biliary

system, A4Is intervention necessary after a first attack of idiopathic acute

pancreatitis?, A4Pelvic floor repair, Long term results of total pelvic floor repair for

neuropathic faecal incontinence, A16Pelvic pouch, The perfect pelvic pouch for ulcerative colitis, A24Pepsin, 24 hour pepsin activity in human subjects, A51Peptic ulcer disease, Peptic ulcer disease in Scotland: the therapeutic

challenges, A46Peptide YY, Is diarrhoea complicating intragastric enteral feeding

caused by an abnormal peptide YY response?, A8Percutaneous endoscopic gastrostomyChange in user's perspective of percutaneous endoscopic gastrostomy

after adoption of a team approach, A69Efficacy of percutaneous endoscopic gastrostomy versus nasogastric

tube in enteral nutrition, A68Endoscopy nurse practitioners: prospective evaluation as first

assistant at PEG tube insertion, A39pH monitoring, Three year follow-up of oesophagitis with endoscopy

and oesophageal pH monitoring, A15pH profile, Does healing of oesophagitis improve ambulatory

oesophageal motility and pH profile? A65Phospholipids

Biliary phospholipids and mucin glycoprotein are altered inoctreotide-induced gallstones, A47

Novel IgA antineutrophil cytoplasmic antibodies against phospho-lipid targets in inflammatory bowel disease, A57

Photodynamic therapyPhotodynamic therapy for cancer in the hamster pancreas using

metatetrahydroxyphenylchlorin, A41Photodynamic therapy for the endoscopic treatment of polyps in

familial adenomatous polyposis, A39Portal hypertensive jejunopathy, A prospective study of portal hyper-

tensive jejunopathy, A61Post-cholecystectomy pain, Is common bile duct dysmotility a common

cause of post-cholecystectomy biliary pain? A3Pre-cut papillotomy, Pre-cut papillotomy: dangerous desire or defini-

tive device, A70Pregnancy, Pregnancy is associated with subsequent reduced rectal

maximal threshold pressure, A17Preterm neonates, Effect of enteral feeding on post natal splanchnic

haemodynamics in human preterm neonates, A69Primary biliary cirrhosis

Effect of ursodeoxycholic acid on serum markers of fibrosis in primarybiliary cirrhosis, A30

Low-dose methotrexate in treatment of primary biliary cirrhosis, A30Surrogate markers of response in a trial of ursodeoxycholic acid and

colchicine in primary biliary cirrhosis, A30The localisation of collagen production by in situ hybridisation in

primary biliary cirrhosis, A30Propranolol, Differing actions ofpropranolol and nitrates in cirrhosis - a

rationale for combination therapy to prevent variceal haemorrhage?A61

Prostaglandins, Prostaglandins contract and relax human gallbladder invitro, A66

Psychological morbidity, Psychological morbidity in inflammatorybowel disease - a case for psychological counselling? A67

Pulmonary arteriovenous shunting, Pulmonary arteriovenous shuntingin cystic fibrosis patients with chronic liver disease may acceleratecardiopulmonary mortality, A61

QT interval, QT interval prolongation and autonomic dysfunction inendstage liver disease: effect of liver transplantation, A31

Quality life assessment, Quality life assessment is an important tool inmeasuring outcome in patients undergoing treatment for carcinomaof the oesophagus, A27

Radiotherapy, Management of strictures after radiotherapy for treat-ment of oesophageal cancer, A28

RANTES, Inflammatory stimuli activate secretion of IL-8 and GROCabut not RANTES in human colonic epithelial cells in vitro, A48

Reactive oxygen species Reactive oxygen species activity and damage inHelicobacter pylori associated gastritis - effect of eradicationtherapy, AIO

Rectal maximal threshold pressure, Pregnancy is associated withsubsequent reduced rectal maximal threshold pressure, A17

Reflux oesophagitisChanges in mucosal neurotransmitters in patients with reflux

oesophagitis, A29Lansoprazole provides greater symptom relief than omeprazole in

reflux oesophagitis, A23Renal blood flow, Alterations in hepatic haemodynamics may contri-

bute to the abnormalities in renal blood flow in liver failure, A33

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Volume 36: Subject index - Supplement No I

Renal function, Mechanisms of changes in renal function following

TIPSS, A32Reticulin antibodies, Detection of endomysial and reticulin antibodies

in coeliac disease using a single substrate: human umbilical cord,

A53Retinoic acid, 9-cis retinoic acid differentially modifies vitamin D2

action in two human colorectal cancer cell lines, A7Rheumatoid factors, Elevation of IgA and IgM rheumatoid factors in

chronic liver disease, A20

Sclerosing cholangitisAntineutrophil cytoplasmic antibody titre but not IgG subclass

distinguishes between primary sclerosing cholangitis and auto-

immune hepatitis, A18Biliary lactoferrin concentrations are increased in active inflammatory

bowel disease: a factor in the pathogenesis of primary sclerosing

cholangitis? A56Production of interferon-gamma by liver and peripheral blood

T-lymphocytes in primary sclerosing cholangitis, A19Self expanding metal endoprostheses, The management of high grade

hilar strictures by the endoscopic insertion of self-expanding metal

endoprostheses, A37Small bowel, A52-54Comparison of small intestinal 5-HT release in secretory states

induced by cholera toxin and E. coli heat labile toxin, A47Correlation between duration of cholera toxin exposure and 5-HT

levels in small intestinal tissue and lumen, A47

Small bowel enteroscopy: should jejunal biopsy be routine? A39

Small bowel transit in HIV-seropositive individuals, A70Small intestinal water movement in basal and cholera toxin induced

secretory states after 5-HT depletion, A69Sodium butyrate, A specific role for sodium butyrate in growth arrest of

colon cancer cells, A6Somatostatin, Changes in the expression of somatostatin and gastrin

mRNA in response to gastrin releasing peptide are altered by

H. pylori infection, A50Somatostatin mRNA, The effect of H. pylori infection on the expression

of somatostatin mRNA in the gastric antrum and corpus, A45

Somatostatin peptides, Role of SSTR2 receptors in the antisecretory

effect of somatostatin in rat distal colon, A48Spasm, 24-hour manometry is essential to diagnose diffuse oesophageal

spasm, A29Starvation, Colonic electrogenic Cl- hypersecretion induced by starva-

tion: purative involvement of basolateral K' conductance, A9

StentingEndoscopic stenting alone and stenting with radiotherapy in non-

resectable cholangiocarcinoma, ASSelf-expanding covered Giaturco stent prevents tumour ingrowth in

malignant dysphagia and seals anastomotic leak, A28

Will laparoscopic biliary bypass replace endoscopic stenting for

malignant obstructive jaundice? A4Stimulation, Can magnetic stimulation of trigeminal and vagal nerve

afferents be used to assess brainstem and cortical swallowing

pathways? A66Strictures, Management of strictures after radiotherapy for treatment of

oesphageal cancer, A28Stroke, Nutritional intake inpatients admitted with acute stroke,

A68Sulphate-reducing bacteria, Incidence and activities of sulphate-

reducing bacteria in patients with ulcerative colitis, A63

Swaliowing, Can magnetic stimulation of trigeminal and vagal nerve

afferents be used to assess brainstem and cortical swallowing

pathways? A66

Technetium, Comparison of 99m technetium-HMPAO labelled leuco-

cyte with 111 indium labelled granulocyte scanning and ultrasound

in the diagnosis of intra-abdominal abscess, A64Terminal ileal mucosa, Human terminal ileal mucosa expresses novel

antimicrobial activity, A64Thalidomide, The treatment of microsporidiosis with thalidomide,

A23Thrombophlebitis

Glyceryl trinitrate does not reduce thrombophlebitis during full

intravenous nutrition through a peripheral vein, A8

Thrombophlebitis is established before occlusion of the vein occurs

during infusion of intravenous nutrition, A68

Tinidazole, Patient factors that predict failure of omeprazole, clari-thromycin and tinidazole to eradicate Helicobacter pylori, A46

TIPS, TIPS transplantation and surgical shunts, A60

TIPSS, A32-33TIPSS shunt function, The role of duplex and colour flow Doppler

ultrasonography in the assessment of TIPSS shunt function,

A20Tonsillectomy, Appendicectomy, tonsillectomy and risk of inflamma-

tory bowel disease, A25

Total parenteral nutritionHypermanganesaemia and TPN: a cause of cholestasis?, A7What is the effect of setting up a nutrition team on the provision of

total parenteral nutrition in a teaching hospital? A clinical audit,A36

Trace metals, Assessment of gastric mucosal and mucus layer elementaltrace metals in H. pylon gastritis using the novel technique ofelectron energy loss spectroscopy, AIO

Transaminase, Liver histology in patients with hepatitis C and normaltransaminase levels, A2

Transcytotic vesicular transport, Cyclosporin-A does not inhibittranscytotic vesicular transport, A19

Transjugular intrahepatic portosystemic stent-shunt, A32-33Tuberculous enteritis, Is tuberculous enteritis important in African

slim disease? A64TUDCA, TUDCA treatment of gallstones in patients at high risk for

surgery, A47Tumour growth, Possible role of cell adhesion molecules in tumour

growth and metastasis, A17Tumour necrosis factor, Severe acute pancreatitis is associated with

elevated serum soluble tumour necrosis factor receptor concentra-tions, A41

Ulcerative colitisCyclosporine for the treatment of acute steroid resistant ulcerative

colitis, A57Desulfovibrio spp: an aetiological agent common to ulcerative colitis

and porcine proliferative enteropathy? A56Direct measurement of rectal nitric oxide in ulcerative colitis, A26Do patients with distal ulcerative colitis undergoing ileal pouch anal

anastomosis have a better outcome than those patients with totalcolitis? A24

Effect of carbopol 934P on the clinical course of active ulcerativecolitis, A22

High expression of iNOS in colonic mucosa in ulcerative colitis, A56Incidence and activities of sulphate-reducing bacteria in patients with

ulcerative colitis, A63Is proximal demarcation of ulcerative colitis determined by the

territory of the inferior mesenteric artery? A26The perfect pelvic pouch for ulcerative colitis, A24Use of a new enzyme linked PCR assay to show increased inducible

nitric oxide synthase and interleukin 8 mRNA in ulcerative colitis,A56

Upper gastrointestinal haemorrhageAn audit of upper gastrointestinal haemorrhage: the effects of a

protocol and staff education, A34Auditing the audits of mortality from upper gastrointestinal haemor-

rhage: a plea for standardisation of methodology, A34Pitfalls in auditing upper gastrointestinal bleeding, A34Specialised bleeding units are the logical way forward in the manage-ment of upper gastrointestinal haemorrhage, A34

Urease activity, Effect of omeprazole therapy on Helicobacter pylon,urease activity and antral gastric histology in patients with duodenalulcer, A21

Ursodeoxycholic acidEffect of ursodeoxycholic acid on serum markers of fibrosis in primary

biiary cirrhosis, A30Efficacy of ursodeoxycholic acid alone and with chenodeoxycholic acid

for cholesterol gallstone dissolution, A42Surrogate markers of response in a trial of ursodeoxycholic acid and

colchicine in primary biliary cirrhosis, A30

Variceal haemorrhage, Multicentre trial of octreotide versus injectionsclerotherapy for acute variceal haemorrhage, A38

Variceal rebleeding, Preliminary results of a randomised, controlledtrial of TIPSS and variceal band ligation in the prevention ofvariceal rebleeding in cirrhosis, A33

VeinsThe basilic is the vein of choice for peripheral infusion of intravenous

nutrition, A68Thrombophlebitis is established before occlusion of the vein occurs

during infusion of intravenous nutrition, A68Vibrio cholerae, Bromelain protease inhibits intestinal secretion caused

by Escherichia coli heat labile and heat stable toxins and Vibriocholerae cholera toxin, A55

Viral infection, Importance of concomitant viral infection and treatmentduring late acute liver allograft rejection, A31

Vitamin D, 9-cis retinoic acid differentially modifies vitamin D, actionin two human colorectal cancer cell lines, A7

Wheat peptide, Coeliac disease: measurement of a toxic wheat peptide ingluten-free foods, A65

Wilson's disease, Isolation of copper-binding proteins in bilecanalicular membranes: a possible link to copper excretion andWilson's disease, A62

974

GutJournal of the British Society of Gastroenterology which

is a registered charity

VOLUME 36 * 1995

Editor: R N Allan

Review Editor: Ian Forgacs

Technical Editor: Jackie Foulds

Editorial Assistant: Michelle Dimler

EDITORIAL BOARDD AdamsM J P ArthurI S BenjaminP BlandIW BoothR ChapmanG J Dockray

C A HartC J HawkeyS G HubscherD KumarM McMahonH O'ConnorP Quirke

D RamptonP J ShorvonD SwallowD G ThompsonB J R Whittle

R G Newcombe(Statistical adviser)

EditorBritish MedicalJournal

INTERNATIONAL ADVISORYB S Anand (USA)C Arvanitakis (Greece)G P van Berge Henegouwen

(Netherlands)G Bianchi-Porro (Italy)A L Blum (Switzerland)M van Blankenstein

(Netherlands)J P Delmont (France)J Dent (Australia)

BOARDD Y Graham (USA)J Hansky (Australia)J Heathcote (Canada)R H Hunt (Canada)J R Jass (New Zealand)S-J Jiang (China)S J Konturek (Poland)S K Lam (Hong Kong)M M Levine (USA)J-R Malagelada (Spain)

R Modigliani (France)T Muto (Japan)G Paumgartner (Germany)D Rachmilewitz (Israel)J Rask-Madsen (Denmark)E Rene (France)A Torsoli (Italy)

VOLUME 36 CONTENTS

No 1 JANUARY 1995 Page Leading articles1 Potential role of superantigen induced activation of cell mediated immune mechanisms in the pathogenesis of

Crohn's disease J P Ibbotson, JTR Lowes5 Platelet dysfunction: a new dimension in inflammatory bowel disease Carole E Collins, David S Rampton9 Surgical emergencies in tropical gastroenterology Chris Holcombe

Helicobacter pylori12 Changes in the intragastric distribution of Helicobacter pylori during treatment with omeprazole R PH Logan,

MM Walker, JJ Misiewicz, PA Gummett, Q N Karim, J H BaronSmall intestine

17 Effect of predigested fat on intestinal stimulation of plasma cholecystokinin and gall bladder motility in coeliacdisease WPM Hopman, G Rosenbusch, M P C Hectors, JRBM JJ,ansen

22 Analysis of crypt cell proliferation in coeliac disease using MI-B 1 antibody shows an increase in growth factorR Przemioslo, NA Wright, G Elia, PJt Ciclitira

28 Studies on the expression of intestinal lactase in different individuals C B Harvey, Y Wang, L A Hughes,DM Swallow, WP Thurrell, VR Sams, R Barton, S Lanzon-Miller, M Sarner

34 Tyrosine phosphorylation in the human duodenum D Kelleher, A Murphy, 0 Sheils, A Long, J7 McDevitt39 Effect of cholecystokinin on lower oesophageal sphincter pressure and transient lower oesophageal sphincter

relaxations in humans M Ledeboer, A A M Masclee, MR Batstra, J B M3JJansen, C B H WLamers

Inflammatory bowel disease45 Soluble interleukin-6 receptors in inflammatory bowel disease: relation to circulating interleukin-6

KMitsuyama, A Toyonaga, E Sasaki, 0 Ishida, H Ikeda, 0 Tsuruta, K Harada, H Tateishi, T Nishiyama,K Tanikawa

50 DNA flow cytometric evaluation of cell cycle distribution in ulcerative colitis: a proposed method for assessingseverity of disease F Bortoluzzi, M Valentini, C Cernigoi, G Toffoli, M Boiocchi, M Poletti, M Sozzi, M Fornasarig,R Cannizzaro, E Bertolissi

55 Selective inhibition of fatty acid oxidation in colonocytes by ibuprofen: a cause of colitis? WE WRoediger,S Millard

60 Controlled trial of oligopeptide versus amino acid diet in treatment of active Crohn's disease J C Mansfield,MH Giaffer, CD HoldsworthGastrointestinal cancer

67 Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using5 aminolaevulinic acid induced protoporphyrin IX - a pilot study J Regula, A J MacRobert, A Gorchein,GA Buonaccorsi, SM Thorpe, GM Spencer, A R WHatfield, S G Bown

76 Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis J WR Mulder,VJ7M Wielenga,MM Polak, FM van den Berg, G R Adolf, P Herrlich, S T Pals, GJ A Offerhaus

81 Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients J Smith-Ravin,J England, I C Talbot, WBodmer

87 Diagnostic value of a guaiac occult blood test and faecal alpha 1-antitrypsin A Moran, D Husband, A FJyones,PAsquith

90 A screening clinic for relatives of patients with colorectal cancer in a district general hospital S Carpenter,M Broughton, C G MarksLarge intestine

93 Colonic mucin synthesis is increased by sodium butyrate IA Finnie, A D Dwarakanath, B A Taylor, J M Rhodes100 Why portal hypertensive varices bleed and bleed: a hypothesis PA McCormick, SA J7enkins, N McIntyre,

A K Burroughs104 Portal and systemic haemodynamic response to acute and chronic administration of low and high dose

isosorbide-5-mononitrate in patients with cirrhosis A L J7ones, I H Bangash, J Walker, KJ Simpson,ND C Finlayson, P C Hayes

110 Energy expenditure and substrate metabolism in patients with cirrhosis of the liver: effects of the pattern of foodintake WPH G Verboeket-van de Venne, KR Westerterp, B van Hoek, G R Swart

117 Increased serum pancreatitis associated protein (PAP) concentration after longterm alcohol consumption: furtherevidence for regular subclinical pancreatic damage after heavy drinking? I Nordback, M J3aakkola, Y L Iovanna,Jf C Dagorn

121

126

Gall stonesDeoxycholic acid in gall bladder bile does not account for the shortened nucleation time in patients withcholesterol gall stones H Noshiro, K Chijiiwa, I Makino, K Nakano, I HirotaComposition of gall bladder stones associated with octreotide: response to oral ursodeoxycholic acidS H Hussaini, S P Pereira, GM Murphy, C Kennedy, J'A H Wass, GM Besser, RH DowlingPancreas

133 Pancreatic vascular regulation in chronic pancreatitis in cats A L Widdison, ND Karanjia, HA Reber137 Profound duodenogastric relux causes pancreatic growth in rats T Gasslander, H Mukaida, MK Herrington,

RA Hinder, TE AdrianCase reports

142 Hepatic venous outflow obstruction in patients with polycystic liver disease: pathogenesis and treatmentW Uddin, J7K Ramage, B Portmann, P Wilson, I Benjamin, K-C Tan, Roger Williams

146 Hepatitis induced by traditional Chinese herbs; possible toxic components JtA Kane, S P Kane, SJ'ain148 Acute hepatitis C infection after sexual exposure C J Healey, D B Smith, J L Walker, E C Holmes, KA Fleming,

R WG Chapman, P Simmonds151 BSG President's biography152 Letters to the editor Book reviews Notes Correction158 Referees

No 2 FEBRUARY 1995161

165

168

Leading articlesLaparoscopic cholecystectomy KE F HobbsHyposplenism in gastrointestinal disease A F Muller, PJ' ToghillArtificial livers - what's keeping them? E Davies, HJ'F Hodgson

Stomach171 Functional defect ofT cells in autoimmune gastritis A Vargas, M Alvarez-Mon, L Manzano, A Albillos,

A Fernandez-Corugedo, FAlbarrdn, A Durantez176 Satiety effects of a physiological dose of cholecystokinin in humans R Lieverse, BM Jansen,

A A M Masclee, C B H WLamers180 Reasons for variations in the use of open access gastroscopy by general practitioners A P S Hungin,

M G Bramble, H O'Callaghan183 Relation between gastric emptying rate and energy intake in children compared with adults B D Maes,

YF Ghoos, BJ Geypens,MI Hiele, PJr Rutgeerts189 Importance of reflux symptoms in functional dyspepsia PK Small, MA Loudon, B Waldron, D Smith,

F C CampbellHelicobacter pylori

193 Effect of Helicobacterpylori eradication on gastric metaplasia of the duodenum S Khulusi, MA Mendall,SBadve,P Patel, C Finlayson, TC Northfield

198 Helicobacter pylori associated with a high prevalence of duodenal ulcer disease and a low prevalence of gastriccancer in a developing nation P Hu, Y Y Li, MH Zhou, M H Chen, G G Du, B Huang, HM Mitchell,S L Hazell

Small intestine203 Gastrin and the growth of the gastrointestinal tract A A Ekundayo, C Y Lee, RA Goodlad209 Rat intestinal mucosal responses to a microbial flora and different diets R Sharma, U Schumacher, V Ronaasen,

M Coates215 Chloride dependent amino acid transport in the human small intestine L KMunck220 Characterisation of the influence of anti-gastrin, anti-epidermal growth factor, anti-oestradiol, and anti-luteinising

hormone releasing hormone antibodies on the proliferation of 27 cell lines from the gastrointestinal tractF Darro, I Camby, A Kruczynski, J3-L Pasteels, Martinez, R Kiss

231 Sequential changes in small intestinal structure and function during rotavirus infection in neonatal ratsA F Salim, A D Phillips, J7A Walker-Smith, M G FarthingCoeliac disease

239 Seroconversion of reticulin autoantibodies predicts coeliac disease in insulin dependent diabetes mellitusM Mdki, T Huupponen, K Holm, 0 HdllstrUm

Coeliac disease239 Seroconversion of reticulin autoantibodies predicts coeliac disease in insulin dependent diabetes mellitus

M Mdki, T Huupponen, K Holm, 0 HallstrdmInflammatory bowel disease

243 Quantification of inflammatory bowel disease activity using technetium-99m HMPAO labelled leucocyte singlephoton emission computerised tomography (SPECT) M Weldon, A M Masoomi, A Britten, Gane,C Finlayson, A EA Joseph, D Maxwell

Gastrointestinal cancer251 Caffeine phenotyping of cytochrome P4501A2, N-acetyltransferase, and xanthine oxidase in patients with familial

adenomatous polyposis A D Spigelman, K C R Farmer, S Oliver, KP Nugent, PN Bennett, L 7 Notarianni,P Dobrocky, R K S Phillips

255 1,25-dihydroxyvitamin D3 and retinoid X receptor expression in human colorectal neoplasms KF Kane,MJ7 S Langman, G R Williams

259 Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues RA McKinnon,WM Burgess, P de laM Hall, SJ_ Roberts-Thomson, FJ Gonzalez, M E McManus

268 Unconjugated secondary bile acids in the serum of patients with colorectal adenomas E Bayerdorffer,GA Mannes, T Ochsenkuhn, P Dirschedl, B Wiebecke, G PaumgartnerLarge intestine

274 Reporting simplified colonic transit studies using radionuclides: clinician friendly reports A Notghi, A Mills,R Hutchinson, D Kumar, L K Harding

276 Prospective study of physical activity and the risk of symptomatic diverticular disease in men WHAldoori,EL Giovannucci, E B Rimm, A Ascherio, M J7 Stampfer, GA Colditz, A L Wing, D V Trichopoulos, WC Willett

283 Natural history and prognosis of diarrhoea of unknown cause in patients with acquired immunodeficiencysyndrome (AIDS) C Blanshard, B G Gazzard

Liver287 Effects of ethanol and protein deficiency on pancreatic digestive and lysosomal enzymes M VApte, S Wilson,

MA Korsten, G WMcCaughan, P S Haber, R C Pirola

Pancreatitis294 Intraluminal gastric pH in chronic pancreatitis P Bovo, G Cataudella,

VDi Francesco, V Vaona, M Filippini, M Marcori, G Montesi, L Rigo, L FruUoni,M P Brunori, M C Andreaus, G CavalliniCase reports

299 A variant alkaline phosphatase found in a case of gastric carcinoma with super bone scan F Kobayashi, T Ikeda,S Tozuka, 0 Noguchi, TFukuma, S Sakamoto, F Marumo, T Komoda, Y Sakagishi, C Sato

303 Increased CA 125 in a patient with tuberculous peritonitis: case report and review of published worksD K O'Riordan, A Deery, A Dorman, 0 E Epstein

306 Colitis ulcerosa complicated by malignant lymphoma: case report and analysis of published works R Lenzen,F Borchard, H Lubke, G Strohmeyer

311 Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprineE FM Posthuma, R G _' Westendorp, A van der Sluys Veer, J7 C Kluin-Nelemans, Ph M Kluin, C BH W Lamers

314 Recurrent gastrointestinal bleeding associated with chronic pancreatitis A PJ7enkins, MM El-Omar,Jf C L Booth, A K Banerjee, KG Burnand, R PH Thompson

317 BSG President's report for 1993-4

Views and reviews

318 International gastroenterology J7enny Heathcote

320 Book reviews

No 3 MARCH 1995 Leading articles321 Intestinal proliferation in coeliac disease: looking into the crypt T C Savidge, JTA Walker-Smith, A D Phillips324 Day surgery and gastroenterology D Fenton-Lee, E Riach, T G Cooke

Contents

Contents

Helicobacter pylori327 Helicobacter pylori infection does not reduce the viscosity of human gastric mucus gel D C Markesich, B S Anand,

GM Lew, D Y Graham330 Serology for Helicobacter pylori compared with symptom questionnaires in screening before direct access

endoscopy MA Mendall, R PJazrawi, JM Marrero, NMolineaux, J Levi, J D Maxwell, T C Northfield334 Mucosal erosions in longterm non-steroidal anti-inflammatory drug users: predisposition to ulceration and

relation to Helicobacter pylori A S Taha, R D Sturrock, R I Russell337 Effect of a test meal on the intragastric distribution of urea in the "C-urea breath test for Helicobacter pylori

J CAtherton, N Washington, P E Blackshaw, J7 L Greaves, A C Perkins, CJ Hawkey, R C Spiller341 Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacterpylori positive and negative

gastritis R Karttunen, T Karttunen, H-P TEkre, T TMacDonald346 Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy D A F Lynch,

NP Mapstone, A M T Clarke, GM Sobala, PJ_ackson, L Morrison, M F Dixon, P Quirke, A TR Axon351 Cell proliferation in the gastric corpus in Helicobacterpylori associated gastritis and after gastric resection

D A F Lynch, N P Mapstone, A M T Clarke, PJ_ackson, M F Dixon, P Quirke, A TR Axon354 Neutrophil degranulation by Helicobacterpylori proteins A Norgaard, L PAndersen, NNielsen

Stomach358 Pharmacological manipulation of gastric juice: thrombelastographic assessment and implications for treatment of

gastrointestinal haemorrhage S E Patchett, D P O'Donoghue363 Impaired gastric relaxation in patients with achalasia F Mearin, M Papo, J3-R Malagelada

Small intestine369 Novel insights into human intestinal epithelial cell proliferation in health and disease using confocal microscopy

T C Savidge, JA Walker-Smith, A D Phillips375 Wheat deficient in gliadins: promising tool for treatment of coeliac disease M Frisoni, G R Corazza,

D Lafiandra, E De Ambrogio, C Filipponi, F Bonvicini, E Borasio, E Porceddu, G Gasbarrini379 Bacterial translocation in the rat model of lectin induced diarrhoea R Shoda, D Mahalanabis, MA Wahed,

MJ AlbertColorectal cancer

382 Analysis of Ha-ras 1 allele frequencies in hereditary non-polyposis colorectal cancer PJyeevaratnam, PJ Browett,NS Van de Water, Jf RJ7ass

385 Variables associated with the risk of colorectal adenomas in asymptomatic patients with a family history ofcolorectal cancer P Gaglia, WSAtkin, S Whitelaw, IC Talbot, C B Williams, JMA Northover, S VHodgson

391 Proliferative compartment deregulation in the non-neoplastic colonic epithelium of familial adenomatouspolyposis SJ Mills, NA Shepherd, PA Hall, A Hastings, J C Mathers, A GunnLarge intestine

395 Immune regulation of human colonic electrolyte transport in vitro WA Stack, SJ Keely, D P O'Donoghue,A WBaird

401 Expression of binding of plasminogen, thrombospondin, vitronectin, and fibrinogen, and adhesive properties byEscherichia coli strains isolated from patients with colonic diseases W Shen, H Steinriuck, A LjunghInflammatory bowel disease

407 Pelvic and perineal complications of Crohn's disease: assessment using magnetic resonance imaging PJ Haggett,NR Moore,J3 D Shearman, S P L Travis, D PJ'ewell, NJ Mortensen

411 Increased expression of cell adhesion molecule P-selectin in active inflammatory bowel disease G M Schurmann,A E Bishop, PFacer, M Vecchio, _' C WLee, D S Rampton, JM Polak

419 Ascitic fluid y interferon concentrations and adenosine deaminase activity in tuberculous peritonitisMA Sathar, A E Simjee, YM Coovadia, P N Soni, SA H Moola, B Insam, FMakumbiLiver

422 Adenine arabinoside 5-monophosphate in patients with chronic hepatitis B: comparison of the efficacy inpatients with high and low viral replication P Marcellin, M Pouteau, M A Loriot, N Boyer, F Degos, P Calis,L Bettan, Y Bacq, H Coppere, J' Didier Grange, PH Bernard, C Degott, S Erlinger,J3-P Benhamou

427 Chronic hepatitis C virus infections: predictive value of genotype and level of viraemia on disease progression andresponse to interferon ae J C L Booth, G R Foster, U Kumar, R Galassini, R D Goldin, J L Brown, H C Thomas

433 Failure to incriminate hepatitis B, hepatitis C, and hepatitis E viruses in the aetiology of fulminant non-A non-Bhepatitis D Mutimer,J3 Shaw, J7 Neuberger, S Skidmore, B Martin, S Hubscher, P McMaster, E Elias

437 Indications, methods, and outcomes of percutaneous liver biopsy in England and Wales: an audit by the BritishSociety of Gastroenterology and the Royal College of Physicians of London I T Gilmore, A Burroughs,I M Murray-Lyon, Roger Williams, D J7enkins, A HopkinsGall stones

442 Holmium-YAG laser for gall stone fragmentation: an endoscopic tool M Jf K Blomley, D A Nicholson, G Bartal,C Foster, A Bradley, M Myers, WMan, S Li, L M Banks

446 Retained common bile duct stones after endoscopic sphincterotomy: temporary and longterm treatment withbiliary stenting D G Maxton, D E F Tweedle, D F MartinPancreas

450 Treatment of pain in chronic pancreatitis by inhibition of pancreatic secretion with octreotide P Malfertheiner,D Mayer, M Biichler, JE Dominguez-Munloz, B Schiefer, H Ditschuneit

455 Antibodies against p53 protein in serum of patients with benign or malignant pancreatic and biliary diseasesP Laurent-Puig, R Lubin, S Semhoun-Ducloux, G Pelletier, C Fourre, M Ducreux, M J Briantais, C Buffet, T SoussiCase report

459 Cyclosporin in the treatment of corticosteroid resistant autoimmune chronic active hepatitis L D Jrackson,E SongSpecial reports

462 Prospecitve audit of upper gastrointestinal endoscopy in two regions of England: safety, staffing, and sedatiomethods MA Quine, GD Bell, R F McCloy, Y E Charlton, H B Devlin, A Hopkins

468 Gastroenterology in the Trent Region in 1992 and a review of changes since 1975 B B Scott

No 4 APRIL 1995

Views and reviews473 International Gastroenterology Monica Acalovschi475 Letters to the editor Book review Notes

A477 Pancreatic Society of Great Britain and Ireland

Leading articles481 Psychological factors in gastro-oesophageal reflux disease B TJ'ohnston, S A Lewis, A H G Love

Contents

483 Acute gastrointestinal haemorrhage in patients treated with anticoagulant drugsC P Choudari, KR Palmer

485 Role of biliary stenting in the management of bile duct stones in the elderly H R Dalton, R W G ChapmanOesophagus

488 Rising death rate from non-malignant disease of the oesophagus (NMOD) in England and Wales M Z Panos,R P Walt, C Stevenson, M J S LangmanOesophageal reflux

492 Omeprazole 10 mg or 20 mg once daily in the prevention of recurrence of reflux oesophagitis CM Bate,SN Booth, J7 P Crowe, R A Mountford, P WN Keeling, B Hepworth-J7ones, M D Taylor, PD I Richardson, SoloInvestigator Group

499 Integrity and characteristics of secondary oesophageal peristalsis in patients with gastro-oesophageal reflux diseaseMN Schoeman, R H Holloway

505 Precipitating causes of acid reflux episodes in ambulant patients with gastro-oesophageal reflux diseaseC P Barham, D C Gotley, A Mills, D AldersonStomach

511 Misoprostol inhibits gastric mucosal release of endogenous prostaglandin E, and thromboxane B, in healthyvolunteers A Mertz-Nielsen, 0 Eskerod, K Bukhave, J Rask-Madsen

516 Cytophotometric and flow cytometric DNA content of isolated glands in gastric neoplasia Y Kitayama,S Nakamura, H Sugimura, I Kino

522 Accelerated gastric epithelial proliferation M R Gray, SJ7 Darnton, J'A Hunt, R W Irlam, J Nemeth,HM Wallace

528 Muscarinic M, receptor inhibition reduces gastroduodenal bicarbonate secretion and promotes gastricprostaglandin E, synthesis in healthy volunteers A Mertz-Nielsen, J Hillingso, 0 Eskerod, K Bukhave,J Rask-MadsenPeptic ulcer

534 A substantial proportion of non-ulcer dyspepsia patients have the same abnormality of acid secretion as duodenalulcer patients E El-Omar, I Penman, J'ES Ardill, KE L McColl

539 Effect of Helicobacterpylori status on intragastric pH during treatment with omeprazole E F Verdz, D Armstrong,R Frazer, F Viani, Jt-P Idstrom, C Cederberg, A L Blum

544 Helicobacter pylori eradication in the African setting, with special reference to reinfection and duodenal ulcerrecurrence JA Louw, WLucke, KJ'askiewicz, A J Lastovica, TA Winter, IN MarksSmall intestine

548 Effect of gliadin and other food peptides on expression of MHC class II molecules by HT-29 cells TMothes,U Bendix, C Pfannschmidt, I Lehmann

553 Role of 5-hydroxytryptamine in intestinal water and electrolyte movement during gut anaphylaxis FH Mourad,L J7 D O'Donnell, E Ogutu, J3A Dias, MJ' G Farthing

558 Effect of gonadectomy on epidermal growth factor values in the gastrointestinal tract of male and female CD-1mice M Sayegh, JTB ElderInflammatory bowel disease

564 Persistent measles virus infection of the intestine: confirmation by immunogold electron microscopy J Lewin,A P Dhillon, R Sim, G Mazure, RE Pounder, A J7 Wakefield

570 Increased faecal mucin sulphatase activity in ulcerative colitis: a potential target for treatment HH Tsai,A D Dwarakanath, CA Hart, J3 D Milton, J7M Rhodes

577 Efficacy and safety of hydrostatic balloon dilatation of ileocolonic Crohn's strictures: a prospective longtermanalysis H Couckuyt, A M Gevers, G Coremans, M Hiele, P RutgeertsLarge intestine

581 Hereditary proctalgia fugax and constipation: report of a second family A F Celik, P Katsinelos, N W Read,M I Khan. T C Donnelly

585 Scintigraphic measurement of ileocaecal transit in irritable bowel syndrome and chronic idiopathic constipationR Hutchinson, A Notghi, N B Smith, L K Harding, D Kumar

590 Colorectal cancer screening in asymptomatic populations A R Hart, A C B Wicks, J F MayberryLiver

599 Serum intercellular adhesion molecule-i levels in chronic hepatitis C: association with disease activity andresponse to interferon a K T Nouri-Aria, J Koskinas, C J Tibbs, B C Portmann, Roger Williams

604 Adhesion molecule expression in primary sclerosing cholangitis and primary biliary cirrhosis S Bloom,K Fleming, R Chapman

610 Octreotide, the reticuloendothelial system, and experimental liver tumour N Davies, H Kynaston, J7 Yates,BA Taylor, SAj7enkins

615 Prevalence and pattern of familial disease in primary biliary cirrhosis A M Brind, G P Bray, B C Portmann,Roger Williams

618 A three year follow up of self expanding metal stents in the endoscopic palliation of longterm survivors withmalignant biliary obstruction S O'Brien, A R WHatfield, P I Craig, S P Williams

Pancreas622 Purification and assay of secretory lithostathine in human pancreatic juice by fast protein liquid chromatography

A Mariani, G Mezzi, A Malesci630 Quantification ofhuman lithostathine by high performance liquid chromatography J-P Bernard, M Barthet,

G Gharib, R Michel, A Lilova, J Sahel, J3-C Dagorn, M De ReggiViews and reviews

637 International Gastroenterology C Arvanitakis639 Letters to the editor Notes

No 5 MAY 1995 Leading articles641 A new class of colorectal cancer gene L Cawkwell, P Quirke644 Liver transplantation for hepatocellular carcinoma Jf McPeake, R Williams647 Recent advances in the endoscopic management of variceal bleeding S G J Williams, D Westaby

Oesophagus649 Effect of topical oesophageal acidification on human salivary and oesophageal alkali secretion CM Brown,

C F Snowdon, B Slee, L N Sandle, WD WReesGastric epithelium

654 Endoscopic detection of ischaemia with a new probe indicates low oxygenation of gastric epithelium in portalhypertensive gastropathy C Piasecki, J Chin, L Greenslade, N McIntyre, A K Burroughs, PA McCormick

Contents

657 Non-steroidal anti-inflammatory drugs and prostaglandin effects on pepsinogen secretion by dispersed humanpeptic cells A I Lanas, J Nerin, F Esteva, R Sainz

664 Effect of capsaicin and chilli on ethanol induced gastric mucosal injury in the rat J Y Kang, CH Teng, A Wee,F C ChenHelicobacter pylori

670 Detection of the intragastric sites at which Helicobacterpylori evades treatment with amoxycillin and cimetidineJ C Atherton, A Cockayne,M Balsitis, G E Kirk, CJ Hawkey, R C Spiller

675 Prevalence of Helicobacterpylori in patients with gall stones before and after cholecystectomy: a longitudinal studyNA Abu Farsakh, E Roweily, M Steitieh, R Butchoun, B KhalilGastrointestinal cancer

679 Primary gastric lymphoma in clinical practice 1973-1992 A FMuller, A Maloney, DJenkins, F Dowling,P Smith, EM Bessell, PJf Toghill

684 Preservation of the spleen improves survival after radical surgery for gastric cancer J P Griffith, HM Sue-Ling,I Martin, M F Dixon, MJ7 McMahon, A TR Axon, D J7ohnston

691 Colonic cell proliferation in two different ethnic groups with contrasting incidence of colon cancer: is there adifference in carcinogenesis? A van 't Hof, K Gilissen, R J Cohen, L Taylor, Z Haffajee, A L Thornley, I Segal

696 South Asian and European colitics show characteristic differences in colonic mucus glycoprotein type andturnover C S Y Probert, B F Warren, T Perry, EH Mackay, J F Mayberry, A P CorfieldCoeliac disease

703 Translocation of gliadin into HLA-DR antigen containing lysosomes in coeliac disease enterocytes K-P Zimmer,C Poremba, P Weber, PJt Ciclitira, E Harms

710 Osteoporosis in treated adult coeliac disease XA McFarlane, A K Bhalla, D E Reeves, L M Morgan,D A F RobertsonInflammatory bowel disease

715 Duration of recurrent ileitis after ileocolonic resection correlates with presurgical extent of Crohn's diseaseG R D'Haens, A E Gasparaitis, SB Hanauer

718 Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn'sdisease D Rachmilewitz, Y S Stamler, D Bachwich, F Karneli, ZAckerman, D KPodolsky

724 Adhesion molecules in inflammatory bowel disease S C Jones, RE Banks, A Haidar, A J H Gearing,IK Hemingway, SH Ibbotson, M F Dixon, A TR AxonLarge intestine

731 Novel germline APC gene mutation in a large familial adenomatous polyposis kindred displaying variablephenotypes RJ7 Scott, R van der Luijt, M Spycher, J3-L Mary, A Muller, Th Hoppeler, M Haner, Hj Muller,S Martinoli, P-L Brazzola, P Meera Khan

737 Constitutive and cytokine induced expression ofHLA molecules, secretory component, and intercellular adhesionmolecule-i is modulated by butyrate in the colonic epithelial cell line HT-29 D Kvale, P BrandtzaegMotility

743 Differential regional effects of octreotide on human gastrointestinal motor function M R von der Ohe,M Camilleri, GM Thomforde, G G KleeLiver

749 Liver cytosolic 1 antigen-antibody system in type 2 autoimmune hepatitis and hepatitis C virus infectionM Lenzi, P Manotti, L Muratori, M Cataleta, G Ballardini, F Cassani, FB BianchiBiliary tree

755 Effect of octreotide on fasting gall bladder emptying, antroduodenal motility, and motilin release in acromegalyM FJ Stolk, KJ3 van Erpecum, HPF Koppeschaar, M Samsom, A J PM Smout, LMA Akkermans, TL Peeters,G P vanBerge-Henegouwen

761 Is biliary lithiasis associated with pancreatographic changes? M Barthet, C Aifriat, J3-P Bernard, P Berthezene,J3-C Dagorn, J Sahel

766 Somatostatin prevents the postoperative increases in plasma amino acid clearance and urea synthesis after electivecholecystectomy H Heindorff, P Billesbolle, S Ligdrd Pedersen, R Hansen, H VilstrupPancreas

771 Diagnosis of pancreatic cancer by 2 ['8F]-fluoro-2-deoxy-D-glucosepositron emission tomography H Friess,J3 Langhans, M Ebert, H G Beger, Jr Stollfuss, SN Reske, M WBiichler

778 Laparoscopic biliary and gastric bypass: a useful adjunct in the treatment of carcinoma of the pancreasM Rhodes, L Nathanson, G Fielding

781 Detection of c-Ki-ras gene codon 12 mutations from pancreatic duct brushings in the diagnosis of pancreatictumours J3-L Van Laethem, P Vertongen, J7 Deviere, J7 Van Rampelbergh, F Rickaert, M Cremer, P RobberechtCase reports

788 Intestinal fatty acid binding protein is available for diagnosis of intestinal ischaemia: immunochemical analysis oftwo patients with ischaemic intestinal diseases T Kanda, H Fujii, M Fujita, Y Sakai, T Ono, K Hatakeyama

792 Fulminant hepatic failure caused by tuberculosis WHussain, D Mutimer, R Harrison, S Hubscher, J NeubergerSpecial report

795 The nurse endoscopistViews and reviews

796 Personal viewpoint KF R Schiller798 Letters to the editor Book review Obituary

No 6 JUNE 1995 Leading articles803 Current views on the pathophysiology of acute biliary pancreatitis A K Banerjee, RJ C Steele806 Soluble adhesion molecules in immune mediated liver disease KJrSimpson, P C Hayes

Hiatus hernia809 Twenty to 40 year follow up of infantile hiatal hernia B TJ7ohnston, IJtCarre, P S Thomas, BJrCollins

Stomach813 Muscarinic receptors in gastric mucosa are increased in peptic ulcer disease A Pfeiffer, WKrdmer, J Friemann,

M Ruge, M Herawi, M Schatzl, U Schwegler, B May, H Schatz819 Prevalence and incidence of peptic ulcer disease in a Danish County - a prospective cohort study SJ Rosenstock,

TJeorgensen825 Gastric emptying of a solid meal is accelerated by the removal of dietary fibre naturally present in food L Benini,

G CasteUlani, F Brighenti, K W Heaton, M T Brentegani, M C Casiraghi, C Sembenini, P Pellegrini, A Fioretta,G Minniti, M Porrini, G Testolin, I Vantini

Contents

Helicobacter pylori831 Helicobacter pylori reinfection with identical organisms: transmission by the patients' spouses K Schultze,

E Hentschel, B Dragosics, A M Hirschl834 Cure of peptic gastric ulcer associated with eradication of Helicobacter pylori K Seppdla, P Pikkarainen,

P Sipponen, E Kivilaakso, MH Gormsen, and the Finnish Gastric Ulcer Study Group838 A population based study of Helicobacter pylori infection in a European country: the San Marino Study. Relations

with gastrointestinal diseases G Gasbarrini, S Pretolani, F Bonvicini, M R A Gatto, E Tonelli, F Megraud,KMayo, G Ghironzi, G Giulianelli, M Grassi

845 High Helicobacter pylori numbers are associated with low eradication rate after triple therapy M Moshkowitz,FM Konikoff, Y Peled, M Santo, A Hallak, Y Bujanover, E Tiomny, T GilatGastrointestinal cancer

848 Chronology of p53 protein accumulation in gastric carcinogenesis M E Craanen, P Blok, WDekker,G _J A Offerhaus, G NJ Tytgat

853 Photodynamic therapy for malignant tumours of the ampulla of Vater A M Abulafi, J TAllardice, N S Williams,N van Someren, C P Swain, C Ainley

857 Colonic epithelium is diffusely abnormal in ulcerative colitis and colorectal cancer P Gibson, 0 Rosella, R Nov,G YoungSmall intestine

864 Stimulation and inhibition of proliferation in the small intestinal crypts of the mouse after in vivo administrationof growth factors C S Potten, G Owen, D Hewitt, CA Chadwick, H Hendry, B I Lord, L B Woolford

874 Histological changes in small bowel mucosa induced by gliadin sensitive T lymphocytes can be blocked byanti-interferon y antibody R TPrzemioslo, KEA Lundin, L M Sollid, J Nelufer, PJ CiclitiraInflammatory bowel disease

880 Microscopic colitis syndrome B Veress, R Lofberg, L Bergman887 P-ANCA in monozygotic twins with inflammatory bowel disease P Yang, G _arnerot, D Danielsson, C Tysk,

E Lindberg891 Evaluation of intestinal permeability in patients with inflammatory bowel disease using lactulose and measuring

antibodies to lipid A T Oriishi, M Sata, A Toyonaga, E Sasaki, K Tanikawa897 Significance of systemic endotoxaemia in inflammatory bowel disease K R Gardiner, M I Halliday, G R Barclay,

L Milne, D Brown, S Stephens, R J Maxwell, B J Rowlands902 Preservation of complete anal sphincteric proprioception in restorative proctocolectomy: the inhibitory reflex and

fine control of continence need not be impaired WG Lewis, M E R Williamson, A S Miller, PM Sagar,PJ Holdsworth, DJ7ohnstonLarge intestine

907 Relationships between defecographic findings, rectal emptying, and colonic transit time in constipated patientsU Karlbom, L Pdhlman, S Nilsson, W Graf

913 First clinical results with a real time, electronic imager as an aid to colonoscopy B P Saunders, G D Bell,C B Williams, J S Bladen, A P Anderson

918 High pH reduces DNA damage caused by bile from patients with familial adenomatous polyposis: antacids mayattenuate duodenal polyposis D K Scates, S Venitt, R K S Phillips, A D SpigelmanLiver

922 Increased PiZ gene frequency for a, antitrypsin in patients with genetic haemochromatosis A-N Y Elzouki,R Hultcrantz, P Stdl, R Befrits, S Eriksson

927 Low prevalence of primary biliary cirrhosis in Victoria, Australia R G P Watson, P WAngus, M Dewar, B Goss,R B Sewell, RA Smallwood, and the Melbourne Liver Group

931 Natural history of bacteriuria in women with primary biliary cirrhosis and the effect of antimicrobial therapy insymptomatic and asymptomatic groups P Butler, J M T Hamilton-Miller, N McIntyre, A K BurroughsGall stones

935 Characterisation of patients with a complete biochemical response to ursodeoxycholic acid R A J7orgensen,E R Dickson, A F Hofmann, S S Rossi, KD LindorCase report

939 Ecstasy induced hepatitis mimicking viral hepatitis R S Dykhuizen, P WBrunt, PAtkinson, J G Simpson,C C Smith

942 Letters to the editor Book reviews NotesA949 British Association for the Study ofthe Liver953 Volume 36: Author Index - Main Headings956 Volume 36: Subject Index - Main Headings965 Volume 36: Author Index - Supplement No 1

968 Volume 36: Subject Index - Supplement No 1

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