MLF HistoryMLF History

ASD repair 1966 – Dr. Robert ASD repair 1966 – Dr. Robert GrossGross

Atrial fib 1990 – medicationsAtrial fib 1990 – medications TIA – 1993TIA – 1993 Coumadin Coumadin

September 6, 1995

The Maze Procedure for The Maze Procedure for Atrial Fibrillation Atrial Fibrillation

Originally an open-heart Originally an open-heart procedureprocedure

Now minimally-invasive in Now minimally-invasive in the OR and the cath labthe OR and the cath lab

An idea that initially helped a An idea that initially helped a selected few can now selected few can now potentially help millionspotentially help millions

Maze Recognition 2005Maze Recognition 2005

Maze Reunion – St. LouisMaze Reunion – St. Louis

ACS MeetingACS Meeting John H. Gibbon, Jr. Lecture: John H. Gibbon, Jr. Lecture:

“Surgery for Atrial Fibrillation”“Surgery for Atrial Fibrillation” Initiates Program: “Negotiating the Initiates Program: “Negotiating the

Maze: From Idea to Laboratory to Maze: From Idea to Laboratory to Operating Room to Start-up to Sale”Operating Room to Start-up to Sale”

James L. Cox – BiographyJames L. Cox – Biography

University of Mississippi – University of Mississippi – UndergraduateUndergraduate

University of Tennessee – MDUniversity of Tennessee – MD Surgery Residency – DukeSurgery Residency – Duke Associate Professor Surgery – DukeAssociate Professor Surgery – Duke Professor/Chief Cardiothoracic Surgery Professor/Chief Cardiothoracic Surgery

– Washington University 14 years– Washington University 14 years Professor/Chairman Cardiothoracic Professor/Chairman Cardiothoracic

Surgery – Georgetown UniversitySurgery – Georgetown University

BiographyBiography Over 300 publicationsOver 300 publications NIH Research grant for 27 years for NIH Research grant for 27 years for

the surgical treatment of cardiac the surgical treatment of cardiac arrhythmiasarrhythmias

Numerous patentsNumerous patents Director of American Board of Director of American Board of

Thoracic SurgeryThoracic Surgery Chairman RRC – Thoracic SurgeryChairman RRC – Thoracic Surgery President of American Association President of American Association

of Thoracic Surgeryof Thoracic Surgery

Surgeon’s SurgeonSurgeon’s Surgeon

Competent/ThoughtfulCompetent/Thoughtful Compassionate/CommunicatorCompassionate/Communicator

St. Louis Maze Reunion patientsSt. Louis Maze Reunion patients

Confidence without arroganceConfidence without arrogance Sense of humorSense of humor

““I hope you are all still in sinus I hope you are all still in sinus rhythm”rhythm”

Role modelRole model

Surgeon’s SurgeonSurgeon’s Surgeon

Element of humilityElement of humility Maze Procedure instead of Cox Maze Procedure instead of Cox

ProcedureProcedure ““I’m flattered to be here”I’m flattered to be here” ““Find guys twice as smart as you Find guys twice as smart as you

and turn them loose”and turn them loose” ““Walk the walk - talk the talk”Walk the walk - talk the talk”

Invited operating surgeon in 40 Invited operating surgeon in 40 international institutionsinternational institutions