In science, there have been numerous studies regarding the mechanism of transport from the cytoplasm to the nucleus. At the time of the paper, there was not much known about the macromolecular export from the nucleus to the cytoplasm. Not much known about the proteins that are involved in RNA export as well. In 1992, an experiment suggests that common factors were used to export a various amount of RNAs.

This paper looks at various classes of RNA and explores if these RNAs are mediated by a specific or a common factors during export. For the study, microinjection was used on Xenopus oocytes to show that RNAs like tRNA, U snRNA, and mRNA, was able to inhibit their own export. The results show that there is a distinct factor that mediate the export of tRNA, 5s RNA, U snRNA, and mRNA.