Interplay: Science - Society

Fitch, Alanah, Yunlong Wang, Sean Mellican, and Susan Macha: Lead Lab Teaching Instrumentation with One Analyte. Analytical Chemistry, 1996, Dec. 1, 727A.

Thus far you have looked atThe areas in dark blue

Interplay: Science - Society

Fitch, Alanah, Yunlong Wang, Sean Mellican, and Susan Macha: Lead Lab Teaching Instrumentation with One Analyte. Analytical Chemistry, 1996, Dec. 1, 727A.

Now you need to considerThe areas in Hot Pink

Designing a Standard Operating Procedure

1. You know how to select an instrumental method2. You know how to create a calibration curve3. You know how to assess the “precision” of the calibration curve

4. How are you going to assess the accuracy of your 1. Sampling2. Digestion

5. How are you going to confirm the stability of the instrument?

Dates and responsible parties

Laboratory certification

Instrument drift is moniteredNot the same as calibrated –

for example checking gas flows,magnet capacity, intensity ofthe voltage for a source lamp, etc

Validated method

Document chain of custody

Controls to documentWorker/instrument/method capacity

Validated method

Internal standards

Based on your previous work

1. How many separate digestions will you need to do on your sample to assess the precision of digestion?

2. How will you confirm that the digestion procedure does not add lead to the final answer?

3. How will you confirm if your individual ability to perform the digestion is compromised?

The answer to these questions results in a standardOperating procedure.

Today:cosmetologists consult the literature search lists I have posted todetermine which articles you need to retrieve from off campus. This needsto be done today in order to have the information back by the weekend

For Friday: “loyola is killing us group” – consult the labs on the web page to findthe standard operating procedure for dust wipe sampling and digestion