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PresidentsAngelo Vacca - Roberto Ria
Honorary PresidentFranco Dammacco
Bari (Italy)November 8-10, 2018
The Nicolaus Hotel
MULTIPLE MYELOMAand related malignanciesFourth Edition 2018
Pict
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by D
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International Congress Preliminary
Program
UNDER THE AUSPICES OF:
Scientific Secretariat:Vanessa DesantisMaria Antonia FrassanitoAurelia LamanuzziAssunta MelaccioRoberto RiaIlaria SaltarellaAntonio G. Solimando
Società Italiana di Ematologia Sperimentale
SIE
Assessorato al Welfaredella Regione Puglia
PRESENTATION
In the last 15 to 20 years significant advancements in the understanding of the pathophysiology of multiple myeloma and related malignancies have led to the adoption of new effective and safe therapies. Thus, the time has come for a thorough biological and clinical update.In planning this international meeting, we have indeed kept in mind this aim which will hopefully provide specialists in Hematology, Oncology and Internal Medicine as well as young researchers, residents, doctoral and undergraduate students with a unique opportunity to deepen and update their knowledge with regard to the available and emerging developments in the biology and management of multiple myeloma and related malignancies.A number of internationally recognized speakers, coming from our own and other countries, are expected to deliver state-of-the-art lectures on cutting edge topics. These will include genetic and epigenetic features of myeloma biology, molecular and biological mechanisms of disease progression, new prognostic factors and novel approaches to evaluate the response to therapy, new therapeutic molecules and combinations thereof specifically targeting tumor cells and/or their microenvironment. Autologous and allogeneic stem cell transplantation will also be the object of intensive scrutiny. Finally, a workshop focused on emerging toxicity and quality of life has been planned. Based on these premises, we are confident that at the end of the meeting all of us will be enriched with fresh stimuli and renewed enthusiasm, with the deep awareness that the enduring challenges posed by multiple myeloma and cognate tumors may now be faced with more rational and effective achievements.
Angelo Vacca, Roberto Ria
Binder Mascha Hamburg, D
Boccadoro Mario Turin, I
Bolli Niccolò Milan, I
Bondanza Attilio Milan, I
Borrello Ivan Baltimore, USA
Bringhen Sara Turin, I
Caers Jo Liege, B
Campanella Alessandro Milan, I
Carniti Cristiana Milan, I
Catalano Lucio Naples, I
Cavo Michele Bologna, I
Colonna Paolo Bari, I
Corradini Paolo Milan, I
Corso Alessandro Pavia, I
Dammacco Franco Bari, I
De Veirman Kim Brussels, B
Derudas Daniele Cagliari, I
Di Raimondo Francesco Catania, I
Einsele Hermann Würzburg, D
Fiedler Ulrike Zürich-Schlieren, CH
Foà Robin Rome, I
Gay Francesca Turin, I
Giuliani Nicola Parma, I
Grosicki Sebastian Katowice, PL
Hájek Roman Ostrava, CZ
Hose Dirk Heidelberg, D
Longo Giuseppe Taormina, I
Malavasi Fabio Turin, I
Martino Massimo Reggio Calabria, I
Massaia Massimo Turin, I
Mauro Francesca Rome, I
Merlini Giampaolo Pavia, I
Montefusco Vittorio Milan, I
Moreau Philippe Nantes, F
Musso Maurizio Palermo, I
Musto Pellegrino Rionero In Vulture, I
Mutis Tuna Amsterdam, NL
Neri Antonino Milan, I
Ocio Enrique M. Salamanca, ES
Patriarca Francesca Udine, I
Petrucci Maria Teresa Rome, I
Podar Klaus Krems An Der Donau, A
Puig Noemi Salamanca, ES
Raab Marc Heidelberg, D
Racanelli Vito Bari, I
Ria Roberto Bari, I
Roccaro Aldo M. Brescia, I
Romano Alessandra Catania, I
Salomo Morten Copenhagen, DK
Semenzato Gianpietro Padua, I
Silvestris Franco Bari, I
Specchia Giorgina Bari, I
Tacchetti Paola Bologna, I
Tassone Pierfrancesco Catanzaro, I
Terragna Carolina Bologna, I
Vacca Angelo Bari, I
Vanderkerken Karin Brussels, B
Walker Brian Little Rock, USA
Zamagni Elena Bologna, I
FAC
ULT
Y
PRO
GR
AM
13.00 - 14.15 Registration of participants
14.15 - 14.45 Welcome address
14.45 - 15.00 Welcome speech and orientation
Franco Dammacco, Angelo Vacca, Roberto Ria
15.00 - 15.40 Opening Lecture Chairperson: Pierfrancesco Tassone
Brian WalkerOngoing Evolution and Increasing Complexity of the Myeloma Genome
15.40 - 17.20 Workshop 1Genetics and epigenetics of multiple myelomaChairpersons: Roman Hájek, Vito Racanelli
15.40 - 16.00 Roman Hájek A quick reflection on the fast progress in genetics of multiple myeloma
16.00 - 16.20 Antonino NeriNon-coding RNA in multiple myeloma
16.20 - 16.40 Carolina TerragnaGenomic instability in multiple myeloma
16.40 - 17.00 Niccolò BolliIdentification of driver events and dissection of subclonal evolution in myeloma with next-generation sequencing approaches
17.00 - 17.20 Klaus PodarTranscription factors in multiple myeloma: new potential targets
17.20 - 17.40 Coffee break
T h u r s d a y , N o v e m b e r 8 , 2 0 1 8
17.40 - 19.00 Workshop 2Immunity in multiple myelomaChairpersons: Angelo Vacca, Karin Vanderkerken
17.40 - 18.00 Ivan BorrelloMarrow-infiltrating lymphocytes and their role in myeloma progression
18.00 - 18.20 Kim De VeirmanTargeting myeloid-derived suppressor cells to bypass myeloma induced immunosuppression
18.20 - 18.40 Massimo MassaiaBone marrow Vγ9Vδ2 T cells: a target for PD-1/PD-L1 inhibition
18.40 - 19.00 Fabio MalavasiPlasma cell receptors as immunological target in multiple myeloma
19.00 - 20.00 Poster RoundChairpersons: Daniele Derudas, Fabio Malavasi
T h u r s d a y , N o v e m b e r 8 , 2 0 1 8
08.30 - 10.30 Workshop 3Biology of progression and organ damage in multiple myelomaChairpersons: Nicola Giuliani, Aldo M. Roccaro
08.30 - 08.50 Karin VanderkerkenThe bone marrow microenvironment as support for myeloma plasma cells
08.50 - 09.10 Aldo M. RoccaroEpigenetic architecture in multiple myeloma
09.10 - 09.30 Nicola GiulianiBiology of myeloma-related bone disease
09.30 - 09.50 Daniele DerudasMyeloma cast nephropathy and monoclonal gammopathies of renal significance (MGRS)
09.50 - 10.10 Alessandro CampanellaMicroenvironmental iron restriction in multiple myeloma
10.10 - 10.30 Ulrike FiedlerA new technology to target the bone marrow microenvironment: MP0250 as a new bispecific drug to treat multiple myeloma
10.30 - 10.50 Coffee break
10.50 - 13.10 Workshop 4Diagnosis and Prognostic FactorsChairpersons: Paolo Corradini, Dirk Hose
10.50 - 11.10 Noemi PuigHow to detect prognostic subclones in myeloma bone marrow
11.10 - 11.30 Cristiana CarnitiThe liquid biopsy in multiple myeloma
11.30 - 11.50 Paola TacchettiHeavy/light chain in multiple myeloma
F r i d a y , N o v e m b e r 9 , 2 0 1 8
11.50 - 12.10 Mascha Binder Next Generation Sequencing for minimal residual disease
12.10 - 12.30 Jo CaersRole of PET/TC in multiple myeloma
12.30 - 12.50 Dirk HoseRisk models as guide to treatment in the newest drugs era
12.50 - 13.10 Enrique M. OcioSmoldering Myeloma
13.10 - 14.10 Lunch lectureChairperson: Robin Foà
Francesca Mauro Secondary immunodeficiency in chronic lymphocytic leukemia and therapeutic approaches
14.10 - 14.40 Keynote LectureChairperson: Gianpietro Semenzato
Hermann EinseleIncorporating novel agents in transplant procedures
14.40 - 16.20 Workshop 5Upfront TherapyChairpersons: Mario Boccadoro, Giorgina Specchia
14.40 - 15.00 Michele CavoFirst line therapy in young patients: early or delayed transplant?
15.00 - 15.20 Alessandro CorsoAfter autologous stem cell transplant: consolidation, maintenance or both?
15.20 - 15.40 Vittorio MontefuscoUpfront therapy in not transplantable patients
15.40 - 16.00 Sara BringhenHow I treat the very elderly patients
16.00 - 16.20 Francesca PatriarcaAllogeneic stem cell transplantation: a chance of cure in selected patients
16.20 - 16.40 Coffee break
F r i d a y , N o v e m b e r 9 , 2 0 1 8
16.40 - 18.00 Workshop 6Relapsed/Refractory MyelomaChairpersons: Philippe Moreau, Marc Raab
16.40 - 17.00 Philippe MoreauThe relapse in the era of third generation drugs
17.00 - 17.20 Marc RaabTransplant at relapse: a chance for eligible patients?
17.20 - 17.40 Francesco Di RaimondoSequence of treatment and personalized therapy
17.40 - 18.00 Francesca GayBenefit and toxicity for the choice of therapy
18.00 - 19.20 Workshop 7Toxicity and Quality of lifeChairpersons: Maurizio Musso, Franco Silvestris
18.00 - 18.20 Morten SalomoQuality of life among multiple myeloma patients
18.20 - 18.40 Paolo ColonnaCardio-oncology and thromboembolism in multiple myeloma
18.40 - 19.00 Lucio CatalanoManagement of pain and bacterial/mycotic infections in myeloma patients
19.00 - 19.20 Pellegrino MustoSecond primary malignancies in multiple myeloma
Dinner
F r i d a y , N o v e m b e r 9 , 2 0 1 8
08.30 - 10.40 Workshop 8New targets and new therapeutic strategiesChairpersons: Franco Dammacco, Tuna Mutis
08.30 - 08.40 Maria Teresa PetrucciSecond generation proteasome inhibitors
08.40 - 09.00 Tuna MutisCD38-targeting immunotherapies in multiple myeloma
09.00 - 09.20 Elena ZamagniAnti-CD38 MoAb alone or in combination for myeloma therapy
09.20 - 10.00 Sebastian GrosickiTargeting SLAMF7 in multiple myeloma
10.00 - 10.20 Attilio BondanzaCAR-T cells in multiple myeloma therapy
10.20 - 10.40 Alessandra RomanoIDO1 and ARG1 as emerging therapeutic target in multiple myeloma
10.40 - 11.00 Coffee break
11.00 - 12.40 Workshop 9Plasma Cell DyscrasiasChairpersons: Giampaolo Merlini, Pellegrino Musto
11.00 - 11.20 Franco DammaccoBiomolecular and therapeutic advancements in Waldenström macroglobulinemia
11.20 - 11.40 Giampaolo MerliniHow I treat AL and AA amyloidosis
11.40 - 12.00 Giuseppe LongoExtramedullary myeloma
S a t u r d a y , N o v e m b e r 1 0 , 2 0 1 8
12.00 - 12.20 Massimo MartinoNon-secretory multiple myeloma
12.20 - 12.40 Roberto RiaPlasma cell leukemia
12.40 - 12.50 Closing RemarksAngelo Vacca, Roberto Ria
S a t u r d a y , N o v e m b e r 1 0 , 2 0 1 8
VENUEThe Nicolaus HotelVia Card. A Ciasca 27 - Bari - ITALYPhone +39-080-5682111Website:www.thenicolaushotel.com
REGISTRATION FEEThe registration fee is € 150,00 (VAT included)Registration fee includes:• participation in the scientific sessions• congress kit• coffee breaks• lunch
DINNERA dinner is scheduled on Friday, November 9, 2018.The cost is € 70,00
PAYMENTPayment of registration fee and dinner can be made through the websitewww.meeting-planner.it (select the congress in the section “Calendario eventi”). Payments can be made by credit card or by bank transfer (all transaction fees should be paid by the participant).An invoice will be sent as confirmation of the registration.
CONTINUING MEDICAL EDUCATION (CME) - event n. 228991This Congress has been assigned n. 12.6 credits.This training event is for 200 M.D. graduates specialized in Internal Medicine, Allergology and Clinical Immunology, Hematology, Oncology, Emergency Medicine, Clinical pathology, Radiology, Medical Genetics, Nephrology, Cardiology, Primary Care Medicine, Biologists and Laboratory Technicians. CME credits can be claimed and your CME certificate issued only if you:• have attended the entire training event• have completed all the parts of the assessment survey and personal data• have passed the CME assessment survey (a score of 75% or higher must be
attained).There can be no exceptions to these mandatory steps.Attendants are also required not to exceed acquiring over 1/3 of their credits forthe three-year period (2017-2019) by recruitment invitation.
AIMS OF THE TRAINING PROCESS: Guidelines, Protocols, Procedures (2)
GEN
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POSTER ABSTRACT SUBMISSIONABSTRACT SUBMISSION DEADLINE: July 30, 2018NOTIFICATION OF ACCEPTANCE: September 14, 2018
Abstracts will be reviewed by the Scientific Committee that will select the 3 best posters to be awarded at the congress.For further information, visit the website: www.meeting-planner.it
LANGUAGEThe official language is English. No simultaneous translation will be available.
CLOTHINGInformal for all occasions.
BADGEYour badge is your admission to the scientific sessions, lunch and coffee breaks.Participants are kindly requested to wear it at all times at the Congress venue.
LIABILITYThe organizers cannot accept liability for injury or damage involving people and property during the Conference. Participants are advised to take out their own personal travel and health insurance for their trip.
CANCELLATION POLICYCancellations must be notified in writing to the Organizing Secretariat ([email protected])Registration fee: within August 31, 2018: 100% refund (except for an administrative charge of € 50,00)within September 30, 2018: 50% refund no refund will be made for cancellations received after that date or for no-shows.
Please note that refunds will only be processed by bank transfer after the Conference dates.
Via Divisione Paracadutisti Folgore, 5 - 70125 BARITEL. 080.9905360 - FAX 080.9905359 - 080.2140203
E-mail: [email protected] - www.meeting-planner.it
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