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International Atomic Energy Agency
Internal Dosimetry Software
ASSESSMENT OF OCCUPATIONAL EXPOSURE DUE TO INTAKES OF
RADIONUCLIDES
International Atomic Energy Agency
Introduction
International Atomic Energy Agency
Internal dosimetry software
Internal dosimetry related calculations are complicated
Biokinetic models
Dosimetric models
Direct measurement system calibrations
Several software packages have been developed to assist the dosimetrist
International Atomic Energy Agency
Software is available for various tasks
Lookup tables Dose coefficients Retention fractions, etc.
Dosimetry calculations Intake Committed equivalent dose Committed effective dose
International Atomic Energy Agency
Dose Coefficients and Intake Fractions
International Atomic Energy Agency
Rad_toolbox
• Available, free of charge at http://ordose.ornl.gov/downloads.html
• This toolbox provides ready access to data of interest in radiation protection of workers and members of the public.
• Data include interaction coefficients for , e- , photon and n radiations, nuclear decay data, biological and physiological data, etc.
• Other supportive data include dose coefficients for intakes of radionuclides, for inhalation, ingestion for members of the public and workers.
• The ORNL TM report is included in the download.
International Atomic Energy Agency
Rad_toolbox
Dose coefficient workers ex ICRP 68
International Atomic Energy Agency
Rad_toolboxContains dose coefficients for single organs (committed equivalent dose) and Committed effective dose .
There is the possibility to transfer the values on an Excel file
Dose coefficients for workers
International Atomic Energy Agency
Rad_toolbox
Dose coefficients for members of the population
International Atomic Energy Agency
ICRP Database of Dose Coefficients
Contains dose coefficients from ICRP Publications 68 (Workers) and 72 (public), including organ doses
Inhalation of 10 different AMADs
10 different integration periods
Text of ICRP 68 and 72 with search function
Biokinetic models for all elements
Results can be saved as ASCII files and printed
International Atomic Energy Agency
ICRP Database of Dose Coefficients
International Atomic Energy Agency
ICRP Database of Dose Coefficients
International Atomic Energy Agency
ICRP Database of Dose Coefficients
Characteristics of output
International Atomic Energy Agency
ICRP Database of Dose Coefficients
On line help tool: Biokinetic model
International Atomic Energy Agency
C. Potter: Health Physics retention fraction CD
• Pathway : Only Inhalation
• Retention/ excretion curves in table form
• CD-ROM attached to HP Nov. 2002 issue, Vol. 83 n. 5
• Intake retention fraction for stable element for respiratory tract, 24h urine, 24h feces, accumulated urine and accumulated feces (useful for 3 day collection of feces) .
• Absorption Types F, M, S; 5 μm AMAD.
• No dose coefficients !
International Atomic Energy Agency
C. Potter: Health PhysicsIntake retention fraction
International Atomic Energy Agency
C. Potter: Health Physics retention fraction CD HP Vol 83, 5 Nov. 2002
Biokinetic model parameters
International Atomic Energy Agency
IAEA SRS 37
• Available, free of charge at www-pub.iaea.org/MTCD/publications/PDF/Pub1190/Pub1190_web.pdf
• Tables :www-pub.iaea.org/MTCD/publications/PDF/Pub1190/tables.pdf
• Characteristics• Pathway : Inhalation, ingestion, injection.
• Absorption types , F, M, S, V.
• AMAD = 1 and 5 μm.
• Vapors
• Tables in logarithmic intervals.
International Atomic Energy Agency
IAEA SRS 37
• Standard worker
• Sub-set of radionuclides present in ICRP 68
International Atomic Energy Agency
IAEA SRS 37
• Retention / excretion function (also skeleton organ)
• Dose coefficients for both inhalation, ingestion , injection.
International Atomic Energy Agency
DCAL
• Available, free of charge at http://ordose.ornl.gov/downloads.html
• DCAL is a comprehensive software system for the calculation of tissue dose and subsequent health risk from intakes of radionuclides or exposure to radionuclides present in environmental media.
• The system includes extensive libraries of biokinetic and dosimetric data and models representing the current state of the art.
• DCAL maybe used either in an interactive mode or in a batch mode and is intended for experienced users with knowledge of computational dosimetry.
International Atomic Energy Agency
DCAL
International Atomic Energy Agency
DCAL
Activity in organs
Rate of equivalent dose
in organs
International Atomic Energy Agency
DCAL
Committed organ doses and committed effective dose
International Atomic Energy Agency
Dose Calculation Software
International Atomic Energy Agency
Dose calculation software
Software that can be used to estimate intake and internal doses has been developed using various techniques for different applications
Table look-up Biokinetic and dosimetric modeling
Inhalation Inhalation or ingestion Single intake Multiple intake
International Atomic Energy Agency
MONDAL3
Available free of charge, on request at http://www.nirs.go.jp:8080/anzendb/RPD/gpmd.php
International Atomic Energy Agency
MONDAL3
Calculates intake and committed effective doses a point at a time.
Several radionuclides
Selection between Inhalation and ingestion
Selection between workers and members of the population
Mode of intake , acute, chronic, uneven chronic.
m(t) values up to 1000 days after intake
Radioinuclide available 3H, 32P, 51Cr, 54Mn, 59Fe, 57Co, 58,60Co, 65Zn, 86Rb, 85Sr, 89,90Sr, 95Zr, 106Ru, 110mAg, 124Sb, 125Sb, 125,129,131I, 134,137Cs, 140Ba, 141,144Ce, 203Hg, 226,228Ra, 228,232Th, 234,235,238U, 237Np, 238,239,240Pu, 241Am, 242,244Cm and 252Cf.
• Selection of AMAD = 0.1, 0.3, 1.0, 3.0, 5.0 e 10 µm for workers• = 1.0 µm for member of the population
International Atomic Energy Agency
MONDAL3 Uneven chronic intake
International Atomic Energy Agency
MONDAL3
m(t) value
Evaluated intake I = M / m(t)
E(50) = e(50) * IM = measurement value
Type of measurement
t = time of measurement
International Atomic Energy Agency
Integrated Modules for Bioassay Analysis IMBA
Development began in 1997 by the NRPB
Features modular structure, interacting via ASCII data sets
Implements latest ICRP biokinetic models
Fitting uses maximum likelihood method
Use data recorded a being less than some minimum detection level
Specify multiple intake regimes
International Atomic Energy Agency
IMBA
Each module developed independently by two separate organizations
Available in four different editions depending on included additional functions
Multiple intake regimes
Up to 30 associated nuclides
Simultaneous bioassay types
International Atomic Energy Agency
IMBA Professional Plus
Present status: IMBA Professional Plus
International Atomic Energy Agency
IMBA
Information available at www.hpa.org.uk/radiation/publications/software/imbapro_plus/index.htm
International Atomic Energy Agency
IMBA
Information
International Atomic Energy Agency
IMBA
Bioassay calculation
International Atomic Energy Agency
IMBA
Use of multiple data-set for unique evaluation via maximum likelihood
From Bioassay to intake From Intake to Bioassay
International Atomic Energy Agency
IMBA
Dose Calculations
International Atomic Energy Agency
AIDE AIDE (Activity and Internal Dose Estimates) is a software for
calculating activities in compartments and committed doses due to occupational exposures, and for performing intake and dose estimates using bioassay data
This software has been continuously developed and tested for more than twenty years.
Due to its extensive previous uses and challenges AIDE has proved to be suitable to all sorts of users, from beginners in internal dosimetry through its use in courses promoted by IAEA ARCAL (Harmonization of Internal Dosimetry Procedures (ARCAL
LXXVIII),) up to advanced users performing evaluations of dose reconstruction.
International Atomic Energy Agency
AIDE
This software comprises three basic parts, which will be briefly described below:
Activity and Internal Dose Calculations,
Bioassay Interpretation, and
Edit Models.
International Atomic Energy Agency
AIDE
Activity and internal dose calculations
It has the aim to calculate activities in compatments and committed doses due to occupational exposure for performing intake and dose estimates using bioassay data
International Atomic Energy Agency
AIDE
Bioassay interpretation , intake evaluation chi squared test for fitting, possibility to de-select bioassay values.
International Atomic Energy Agency
AIDE The Model Editing form: Possibility to edit
different model from default ICRP models
International Atomic Energy Agency
AIDE Detail of an original model: Source->Target
fractions and biological half lives
A demonstration of AIDE will be performed next week.
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International Atomic Energy Agency
IDEA - System
Developed as spin-off project of the Research Center Karlsruhe. Expert system. Based on IDEAS Guidelines.
International Atomic Energy Agency
Software Information Contacts
RAD_Toolbox
http://ordose.ornl.gov/downloads.html
ICRP Database of Dose Coefficients
http:// www.icrp.org
C. Potter. Intake retention fraction Health Physics
Sellers of Health Physics
International Atomic Energy Agency
Software Information Contacts
DCAL
http://ordose.ornl.gov/downloads.html
MONDAL3
http://www.nirs.go.jp:8080/anzendb/RPD/gpmd.php
IMBA
www.hpa.org.uk/radiation/publications/software/imbapro_plus/index.htm
International Atomic Energy Agency
Software Information Contacts
IAEA SRS 37
http://www-pub.iaea.org/MTCD/publications/PDF/Pub1190/
Pub1190_web.pdf
DCAL
http://ordose.ornl.gov/downloads.html
MONDAL3
http://www.nirs.go.jp:8080/anzendb/RPD/gpmd.php
International Atomic Energy Agency
Software Information Contacts
IMBA
www.hpa.org.uk/radiation/publications/software/imbapro_plus/index.htm
AIDE
Rodolfo Cruz-Suarez at IAEA
IDEA-System
http://www.idea-system.com