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INTEGRAL UNIVERSITY LUCKNOW
SYLLABUS
of
B.TECH. BIOTECHNOLOGY
2016-17
SYLLABUS & EVALUATION SCHEME FOR
B. TECH. BIOTECHNOLOGY
STUDY & EVALUATION SCHEME
B. TECH. Biotechnology
(w.e.f.- July 2016)
2nd
Year III Semester
Sl.
No
Course
Category
Subject
Code
Name of the Subject
Periods Evaluation Scheme
Subject
Total Sessional (CA) End Sem.
Exam.
(ESE) L T P C CT TA Total
1. DC BE-201 Biochemistry 3 1 0 4 25 15 40 60 100
2. DC BE-202 Microbiology 2 1 0 3 25 15 40 60 100
3. ESA ME -221 Fluid Flow and Solid
Handling 2 1 0 3 25 15 40 60 100
4. ESA MT-203 Numerical Analysis &
Statistical Analysis 2 1 0 3 25 15 40 60 100
5. DE
CS-228 Concepts of web
development
2 1 0 3 25 15 40 60 100 BE-205 Plant Physiology
BE-206 Animal Physiology
6. ESA ES -202/
CS-203
Disaster Management/
Cyber Law & Information
Security
2 1 0 3 25 15 30 60 100
7. HM
BM-226 Human Values &
Professional Ethics 3 0 0 ** 0 0 0 50* 50*
8. DC BE -203 Biochemistry lab 0 0 6 3 30 30 60 40 100
9. DC BE -204 Microbiology lab 0 0 6 3 30 30 60 40 100
10. ESA ME -223 Fluid Mechanics lab 0 0 4 2 30 30 60 40 100
Total 16 6 16 27 240 180 410 480 900
L – Lecture T – Tutorial P – Practical C – Credits CT – Class Test TA – Teacher
Assessment
Sessional Total (CA) = Class Test + Teacher Assessment
Subject Total = Sessional Total (CA) + End Semester Examination (ESE)
BS – Basic Sciences DC – Departmental Core
HM – Humanities OE – Open Elective
DE – Departmental Elective ESA – Engineering Sciences & Arts (Foundation Course &
Engineering Courses)
BIOCHEMISTRY
BE-201
(w.e.f.- July 2016)
L T P C
3 1 0 4 Unit I [08] Role of water in biological processes: Solvent, solute, solutions, water and its properties,
hydrogen ion concentration, Buffers system. General structure, function and classification of
carbohydrates (mono, di and poly sacharride.), lipids (Fatty acids, Phospholipids, Glycolipids,
Waxes), proteins (primary, secondary and tertiary) and nucleic acid (Purines, pyrimidines,
nucleosides, nucleotides.). Structure and functions of vitamins and hormones.
Unit II [08] Carbohydrates Metabolism: Introduction, Glycolysis and its regulation, Oxidative and
reductive decarboxylation, TCA cycle, Amphibolic role of TCA cycle, Anaplerotic reactions,
glyoxylate cycle, pentose phosphate pathway, Oxidative phosphorylation (energy
metabolism). Biosynthesis of polysaccharides: Photosynthesis, gluconeogenesis.
Unit III [08] Lipid metabolism: Oxidation of fatty acids- saturated and unsaturated, beta, gamma, omega
oxidations and regulations. Biosynthesis of fatty acids, cholesterol and phospholipids.
Unit IV [08] Amino acid metabolism: Biosynthesis and oxidation of glutamate, serine and aspartate family
amino acids and their regulation. Urea cycle, Nitrogen fixation, (Biological, nif gene).
Unit V [08] Nucleic acid metabolism: Biosynthesis of purines & pyrimidines by de novo & salvage
pathway and their regulations. Biodegradation of purines and pyrimidines and regulation.
Books recommended: 1. Hames and Hooper; Instant notes on biochemistry; Viba Books PVT. Ltd.
2. Nelson, Cox; Lehninger's, Principle Biochemistry; Macmillan Worth Publication
3. L.Stryer; Biochemistry;
4. Voet and Voet; Biochemistry; Freeman WH and Co., NewYork
5. Mathews et al; Biochemistry; Pearson education.
6. S.C Rastogi; Biochemistry; Tata Macgraw.
MICROBIOLOGY
BE-202
(w.e.f. July 2016)
L T P C
2 1 0 3
UNIT-1 [8]
Introduction to microbiology: definition, history of microbiology (from1684 to modern era of
microbiology), Biogenesis and Abiogenesis, Koch’s postulates. Basics knowledge of
microorganisms: Bacteria, fungi, viruses, actinomycetes, protozoa etc. prokaryotic and
eukaryotic cells, Structure of bacterial cell wall: External and Internal, Gram positive and Gram
negative bacteria.
UNIT-2 [8]
Principles of microscopy: light microscope (magnification and resolution), bright field
microscope, phase contrast, dark field, TEM and SEM microscopy, Gram staining and endospore
staining.
UNIT-3 [8]
Microbial nutrition and growth: microbial requirements of macro and micronutrients, microbial
media and types, microbial isolation techniques: dilution, pour plate and streak plate, Microbial
growth curve and growth measurements, pure culture, starter culture, cultural characteristics of
bacteria, classical, nutrional and modern bacterial taxonomy, Phylogenetic tree of bacteria.
UNIT-4 [8]
Extremophiles: thermophiles, psychrophiles, acidophiles, alkaliphiles etc. Nitrogen fixing
bacteria, Coliform bacteria: Microbiological examination of fecal contaminated water, Food and
water borne infectious diseases: (botulism and salmonellosis), Control of microorganisms:
Physical (autocalve, filteration, radiation and pasteurization) and chemical methods (antibiotics,
alcohol and halogens).
BOOKS RECOMMENDED:
1. Prescott, Harley and Klevin: Microbiology; 2nd
ed
2. Brock, Micheal and Clark: Microbiology of Microorganisms; 12th
edition
3. Introduction to Microbiology: Pelczar
FLUID FLOW AND SOLID HANDLING
ME -221
(w.e.f.- July 2016)
L T P C
2 1 0 3
Unit I [08]
Solid and their handling Properties of solids, screening, industrial screening equipment, determination of particle size,
screen analysis, size reduction of solids, stages of reduction, operating variables, intermediate
and fine size reduction, power requirement and mechanism, Power driven machines: Crushers,
grinders and conveyers.
Unit II [08]
Fluid flow Properties of fluids, Fluid Statics: Fluid pressure, Hydrostatic Law and Manometers, Fluid
dynamics: Euler’s equation of motion, Bernoulli’s equation from Euler’s equation, Applications
of Bernoulli’s equation. Minor losses in pipe flow.
Unit III [08]
Flow measurements Construction, working and application of flow measuring devices: Orifice meter, Nozzle flow
meter, Venturimeter, Rota meter and Pitot tube. Simple calculation on them.
Unit IV [08]
Pumping and compressing Centrifugal Pump: Classifications, working, Introduction to vector diagram and work done by
impeller. Reciprocating pump: Reciprocating pump theory, Slip and coefficient of discharges,
Indicator diagram, Effect and acceleration, Work saved by fitting air vessels. Introduction of
positive displacement pump, blowers and fluidization.
Books recommended: 1. Introduction of Fluid Mech'anics by Robert W. Fox and Slan T. Mcdonald, John urley & sons,
Ny. Fourth Ed.
2. Unit Operation in Chemical Engg., Mccable Smith., 5th edition
3. Bedger W.L. and Bancharo J. T. "Introduction to Chemical Engineering" Tata McGraw
publication House.
4. Hydraulic Machines: Jagdish Lal, Metropolitan Book Co.
5. Hydraulics and Fluid Mechanics: Modi and Seth, Standard Book House
Numerical and Statistical Analysis
MT-203
(w.e.f. July 2016)
L T P C
2 1 0 3
Unit-I [7]
Errors in numerical computations, numerical solution of algebraic and transcendental
equations by Bisection method, Iteration method, Regula false method, Newton-
Raphson’s method.
Unit-II [9]
Finite differences: forward and backward differences, properties of operators, factorial
polynomials, Interpolation: Newton Gregory forward and backward interpolation formula.
Interpolation formula for unequal intervals, divided differences formula, central
interpolation formula: Bessel, Stirling and Laplace Everett's interpolation formulae.
Unit-III [7]
Numerical differentiation, Numerical integration by Trapezoidal rule, Simpson’s 1/3 rule,
3/8 rule, Boole's rule, Weddle’s rule.
UNIT-IV [8]
Probability: Classical and axiomatic definition of probability. Addition and Multiplication
theorem of probability. Conditional probability. Probability distributions: Binomial
distribution, Poisson distribution and Normal distribution.
Unit -V [9]
Testing of Hypothesis: Statistical hypothesis, null and alternative hypothesis, simple and
composite hypothesis, critical region, type I and II error, power of a test. Test of significance
based on t, F and chi-square distribution. Basic concepts of Simple random sampling and
Stratified random sampling. Analysis of variance (ANOVA): One-way and two way
classification.
Reference Books:
1. Text book of Numerical Analysis: H.C. Saxena (S. Chand Publication)
2. Numerical Analysis: S. S., Shastri
3. Numerical Analysis: B.S. Grewal.
4. Numerical Analysis: A.R. Vashistha.
5. Q.S Ahmad, V. Ismail and S.A Khan: Biostatistics, laxmi Publications Pvt.Ltd.
6. S.C. Gupta and VK. Kapoor: Fundamental of Mathematical Statistics, Sultan Chand
publication.
DISASTER MANAGEMENT
ES-202 (w.e.f.- July 2016)
L T P C
2 1 0 3 Objective:
The objective of this course is to familiarize the student with basic management principles
relating to disaster management and mitigation techniques.
Units I [8] Concept of disaster management. Types of disaster and their impact: Natural and Man- Made,
Like- Earthquakes, Floods, Tsunami, Droughts, Cyclones, Avalanches, Forest Fire, Terrorism
related Disaster etc. Assessment of human and Economic losses.
Units II [8] Impact of extensive Industrialization. Impact of Global Warming and Environmental
Degradation. National and global disasters.
Units III [8] National policy for disaster Management, Elementary Knowledge of the Disaster Management
Act 2005. Types of Responses: Central, State, District Level, Peoples Community participation
in Disaster Management. Post-Disaster Management and Rehabilitation measures.
Unit IV [8] Capacity Building for meeting disasters. Long term measures for preventions of disasters.
Mitigation technique/strategies: Early warning systems, Data sharing at national and
international level.
References: 1. Disaster management by Dr. V.K Sethi
2. The great Sumatra Earthquakes and Indian Ocean tsunami of December 2004- the effects of
main land India and in the Andaman and Nicobar Island, published by IIT Kanpur.
3. Environmental managaenet by Dr. Shakeel Ahmad
4. Hazards, disasters and your community, ministry of home affairs.
CYBER LAW AND INFORMATION SECURITY
CS-203 (w.e.f.- January 2017)
L T P C
2 1 0 3 Unit1 [8] Fundamentals of Cyber Law: Jurisprudence of Cyber Law, Object and Scope of the IT Act 2000,
Introduction to Indian Cyber Law, Unicitral Model Law, ISP Guideline. Intellectual property
issues and cyber space, Indian perspective, Overview of Intellectual property related legislation
in India, Patent, Copy Right, Trademark law, Law related to semiconductor layout & design.
Unit 2 [8] E - Commerce: Security Threats to E - Commerce, Virtual Organization, Business Transactions
on Web, E-Governance and EDI, Concepts in Electronics payment systems, E-Cash,
Credit/Debit Cards, E- Agreement, Legal recognition of electronic and digital records, E-
Commerce Issues of privacy, Wireless Computing- Security challenges in Mobile devices.
Digital Signatures - Technical issues, legal issues, Electronic Records, Digital Contracts,
Requirements of Digital Signature System.
Unit 3 [8] Investigation and Ethics: Cyber Crime, Cyber jurisdiction, Cyber crime and evidence act,
Treatment of different countries of cyber crime, Ethical issues in data and software privacy,
Plagiarism, Pornography, Tampering computer documents, Data privacy and protection, Domain
Name System, Software piracy, Issues in ethical hacking. Internet security treats: Hacking,
Cracking, Sneaking, Viruses, Trojan horse, Malicious Code & logic bombs. Introduction to
biometric security and its challenges, Finger prints. Cyber crime forensic: CASE STUDY in
Cyber Crime.
Unit 4 [8] Information security- Information Systems and its Importance, Role of Security in Internet and
Web Services, Principles of Information Security, Classification of Threats and attacks, Security
Challenges, Security Implication for organizations, Security services - Authentication,
Confidentiality, Integrity, Availability and other terms in Information Security, Information
Classification and their Roles. Introduction to Cryptography, Issues in Documents Security,
Keys: Public Key, Private Key, Firewalls, Basic Concepts of Network Security, Perimeters of
Network protection & Network attack, Need of Intrusion Monitoring and Detection.
References:
1. Harish Chander “Cyber Law and IT Protection” , PHI Publication, New Delhi
2. Merkov, Breithaupt “ Information Security”, Pearson Education
3. “Cyber Law in India” - Farooq Ahmad-Pioneer books.
4. K. K. Singh, Akansha Singh “Information Security and Cyber law”, Umesh Publication, Delhi
HUMAN VALUES & PROFESSIONAL ETHICS
BM-226
Maximum Marks: 50
External Assessment: 50
L T P C
3 0 0 0
Unit-1 [6]
Human Value Education: Understanding the need, basic guidelines, content and process for Value Education, Self
Exploration - Its content and process; ‘Natural Acceptance’ and Experiential Validation- as the mechanism for self
exploration, Continuous Happiness and Prosperity- A look at basic Human Aspirations, Right understanding,
Relationship and Physical Facilities- the basic requirements for fulfillment of aspirations of every human being with
their correct priority, Understanding Happiness and Prosperity correctly.
Unit-2 [6]
Introduction to Ethical Concept: Definition of industrial ethics and values, Ethical rules of industrial worker.
Values and Value Judgments. Moral Rights and Moral rules, Moral character and responsibilities. Privacy,
Confidentiality, Intellectual Property and the Law. Ethics as Law
Unit-3 [6]
Professional Responsibility: The basis and scope of Professional Responsibility, Professions and Norms of
Professional Conduct, Ethical Standards versus Profession, Culpable mistakes, the Autonomy of professions and
codes of ethics. Employee status and Professionalism. Central Professional Responsibilities of Engineers: The
emerging consensus on the Responsibility for safety among engineers, hazards and risks.
Unit-4 [6]
Engineers Ethics: Senses of 'Engineering Ethics' - variety of moral issues - types of inquiry - moral dilemmas -
moral autonomy - Kohlberg's theory - Gilligan's theory - consensus and controversy – Models of Professional Roles
- theories about right action - Self-interest - customs and religion - uses of ethical theories. Valuing Time – Co-
operation – Commitment.
Unit-5 [6]
Global Issues: A Glimpse of Life Stories: Life story of Prophet Mohammad, Mahatma Gandhi, Swami
Vivekanand, Marie Curie and Steve Jobs.
Multinational corporations - Environmental ethics - computer ethics - weapons development - engineers as
managers-consulting engineers-engineers as expert witnesses and advisors -moral leadership
Reference Readings:
Text Book
1. R R Gaur, R Sangal, G P Bagaria, 2009, A Foundation Course in Value Education.
2. Mike Martin and Roland Schinzinger, “Ethics in Engineering”, McGraw-Hill, New York 1996.
3. Govindarajan M, Natarajan S, Senthil Kumar V. S, “Engineering Ethics”, Prentice Hall of India, New Delhi, 2004.
Relevant CDs, Movies, Documentaries & Other Literature:
1. Value Education website, http://www.uptu.ac.in
2. Story of Stuff, http://www.storyofstuff.com
3. Al Gore, An Inconvenient Truth, Paramount Classics, USA
4. Charlie Chaplin, Modern Times, United Artists, USA
5. IIT Delhi, Modern Technology – the Untold Story
6. The Hundred, Michael Hart
BIOCHEMISTRY LAB
BE-203 (w.e.f.- July 2016)
L T P C
0 0 6 3 1. Estimation of carbohydrates
2. Estimation of proteins
3. Estimation of nucleic acids
4. Isoelectric precipitation
5. Separation of amino acids by paper chromatography
6. Extraction of lipids
7. Thin layer chromatography
8. Gel electrophoresis
9. Assay of enzyme activity and enzyme kinetics
Books recommended: 1. S.K Sawhney; Introductory Practical biochemistry; Narrosa Pub.
2. J. Jayaraman; Lab. Manual in Biochemistry; New Age Int. Pub.
3. Wilson and Walker; Practical Biochemistry; Cambridge publication. David T
Plummer; An introduction to practical biochemistry; Tata McGraw Hill.
MICROBIOLOGY LAB
BE-204 (w.e.f.- July 2016)
L T P C
0 0 6 3
1. Preparation of nutrient agar slants, plates and nutrient broth and their
sterilization. (Microwave Oven, Heating mantles, Fridge, Heating Oven, Tube
racks)
2. Inoculation of agar slants, agar plate and nutrient broth (Incubators, Water bath,
Laminar hood, dry heat sterilizer i.e. bead sterilizer)
3. Culture of microorganisms using various techniques. (Shakers i.e. Cooling and
Open shaker).
4. Simple and differential staining procedures, endospore staining, flageller
staining,
5. Cell wall staining, capsular staining, negative staining. (Moist chambers, spirit
lamps, slides, loops & microscopes, haemocytometer)
6. Bacterial colony counting. (Moist chambers, spirit lamps, slides, loops &
microscopes, haemocytometer)
9. Observation of different vegetative, capsular and spore forms of bacteria
&Fungus (under various microscopes).
10. Isolation of microbes from soil samples and determination of the number of
colony forming units. (UV spectrophotometer, Colony counters etc.)
11. Study of growth curve of E. coli
Books recommended: 1. Lab Manual in microbiology by P Gunasekaran (New Age Int. Pub.)
FLUID MECHANICS LAB
ME -223
(Say minimum 8 experiments out of the following) (w.e.f.- July 2016)
L T P C
0 0 4 2
1. To verify Bernoulli’s equation experimentally.
2. To calibrate a venturimeter meter and study the variation of coefficient of
discharge with Reynolds number.
3. To calibrate an orifice and study the variation of coefficient of discharge with
Reynolds number.
4. To study the velocity distribution in a pipe.
5. To study the transition, from laminar to turbulent flow and determine the lower
critical Reynolds number.
6. To study the variation of friction factor for turbulent flow in smooth commercial
pipes.
7. To verify impulse momentum equation experimentally and compare the force
exerted by the jet on different shapes of vanes. (flat, hemispherical).
8. To determine experimentally the metacentric height of a ship model.
9. To plot the flow net for a given model with the help of Heleshwaw apparatus.
10. To determine the coefficient of discharge of an orifice of a given shape. Also
determine the coefficient of velocity and coefficient of contraction of the orifice.
11. To calibrate a given v-notch or a rectangular notch and determine the
coefficient of discharge
Concepts of Web Development
CS-228
(w.e.f. July 2016)
L T P C
2 1 0 3
Unit 1
Introduction and Web Development Strategies
History of Web, Protocols governing Web, Creating Websites for individual and Corporate
World, Cyber Laws, Web Applications, Writing Web Projects, Identification of Objects, Target
Users, Web Team, Planning and Process Development. [6]
Unit 2
HTML/DHTML
Introduction, Objectives, Introduction to Universal Resource Identifier (URI) – Fragment
Identifiers and Relative URI’s, History of HTML, SGML, Structure of HTML/DHML
Document, Switching between opened Windows and browser (Container tag, Empty tag,
Attribute), Basic Tags of HTML, Heading tag, FONT tag and Attributes, Formatting Text,
Ordered List, Unordered List, Creating Links, Tables, Frames. [6]
Unit 3
CSS (Cascading Style Sheet)
Introduction, Syntax, Inclusion, Measurement Units, Colors, Backgrounds, Fonts, Text, Images,
Links, Tables, Borders, Margins, Lists, Padding, Cursors Outlines, Dimension, Scrollbars,
Introduction of XML. [7]
Unit 4
JavaScript
Overview, Syntax, Enabling, Placement, Variables, Operators, If…Else, Switch Case, While
Loop, For loop, For…In, Loop Control, Functions, Events, Cookies, Page Redirect, Dialog
Boxes, Void Key Word, Page Printing. [6]
Unit 5
PHP Hypertext Preprocessor (PHP)
Introduction of PHP, Common Uses of PHP, Characteristics of PHP, “Hello World” script in
PHP, Environment Setup, Syntax Overview, Variables, Constants, Operators, Decision Making,
Loop Arrays, String Web Concept. [7]
References: 1. Burdman, “Collaborative Web Development”, Addison Wesley.
2. Jeffrey C. Jackson, “Web Technologies – A Computer Science Perspective”, Pearson Education.
3. XML & Related Technologies by Atul Kahate, Pearson Education India.
4. PHP Reference: Beginner to Intermediate PHP5 By Mario Lurig
Plant Physiology
BE-205
(w.e.f. July 2016)
L T P C
2 1 0 3
UNIT I 8
Plant cells, tissues, and organs; cell organelles and their physiological functions; Structure and
physiological functions of cell walls; Growth and development in plants
UNIT II 8
Transport in plants: Movement of water, gases and nutrients; Cell to cell transport-Diffusion,
facilitated diffusion, active transport; Plant – water relations – Imbibition, water potential,
osmosis, plasmolysis; Long distance transport of water – Absorption, apoplast, symplast,
transpiration pull, root pressure and guttation; Transpiration – Opening and closing of stomata;
Uptake and translocation of mineral nutrients, Transport of food, phloem transport
UNIT III 8
Mineral nutrition: Essential minerals, macro and micronutrients and their role; Mineral
deficiency and their symptoms; Mineral toxicity; Elementary idea of Hydroponics as a method to
study mineral nutrition
UNIT IV 8
Role of growth regulators in plants-auxin, gibberellin, cytokinin, ethylene, ABA; Seed
dormancy; Vernalization; Phytochromes- mode of action; photoperiodism- short day, long day
and day neutral plants; photoperiodic induction; photoperiod and plant flowering
Reference Books
1. Plant Physiology by Lincoln Taiz and Eduardo Zeiger
2. Plant Physiology by Frank Salisbury and Cleon Ross
3. Text Book of Plant Physiology, Biochemistry, and Biotechnology by V.K. Varma and Mohit
Varma, S. Chand Ltd.
ANIMAL PHYSIOLOGY
BE-206
(w.e.f. July 2016)
L T P C
2 1 0 3
Unit I Tissues: Types of tissue. Epithelium- organization and types. The basement membrane. Bone and
cartilage. The extracellular matrix of epithelial and nonepithelial tissues. Elementary details of ECM
components. Blood and circulation - Composition and functions of blood. Separation of plasma and
serum. Plasma proteins in health and disease. Red blood cells- formation and destruction. The RBC
membrane- principal proteins (spectrin, ankyrin, glycophorins). Composition and functions of WBCs.
Blood coagulation- mechanism and regulation. Fibrinolysis. Anticoagulants. [8]
Unit II Cardiovascular and Respiratory System: Comparative anatomy of heart structure, myogenic
heart, specialized tissue, ECG – its principle and significance, cardiac cycle, heart as a pump, blood
pressure, neural and chemical regulation. Respiratory system - transport of gases, exchange of gases,
waste elimination, neural and chemical regulation of respiration. [8]
Unit III Digestive and Excretory system: Digestion, absorption, energy balance, BMR. Digestion and
absorption of carbohydrates, lipids, proteins and nucleic acids. Excretory system - Comparative
physiology of excretion, kidney, urine formation, urine concentration, waste elimination, micturition,
regulation of water balance, electrolyte balance. . [8]
Unit IV Neuromuscular system and Endocrinology: Structure of neuron. Propagation of action
potential: The neuromuscular junction. The acetylcholine receptor. Gross neuroanatomy of the brain and
spinal cord, central and peripheral nervous system. Structure of skeletal muscle. Sequence of events in
contraction and relaxation of muscle. Endocrine glands, basic mechanism of hormone action, hormones
and diseases. [8]
Books for Reference:
1. Lodish et al. Molecular Cell Biology 6th ed. 2007, WH Freeman
2. Murray et al. Harper’s Illustrated Biochemistry 27th ed. McGraw Hill 2006
3. Smith et al. Principles of Biochemistry. Mammalian Biochemistry. McGraw Hill 7th ed.
4. De Robertis and De Robertis. Cell and Molecular Biology.Lippincott 2001
5. Alberts et al. Molecular Biology of the cell 5th ed. Garland Sci. 2007.
6.Guyton and Hall.Textbook of Medical Physiology 12 ed 2011