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Innovations in the Ag Biologicals Sector:Why All the Recent Excitement?
Presentations• Biopesticides Overview Eric Sachs• Bayer CropScience Marcus Meadows-Smith• Monsanto Company Kelly Fleming• University of Capetown Jennifer Thompson
Panel Q&A
Innovative Natural Products for Pest Management in Agriculture and Water
BIOPESTICIDESPam Marrone, PhD
CEO & Founder
Defining the Basics
Page 4
Characteristics of Biopesticides
• Natural products derived from plants or other natural sources, comprised of microorganisms or other organisms
• Insecticides, fungicides, herbicides, nematicides, plant growth regulators, insect growth regulators, repellents
• Can be synthetically made • Must be nature-identical• Highly biodegradable and non-persistent• Generally comprise the lowest risk category of pest management
Products• 64-year history of safe use with no environmental or human safety
issues
Page 5
History of Biopesticides
• The first, and still most, widely used biopesticide included spores of the bacteria Bacillus thuringiensis (Bt).
• In 1901, Bt was isolated from a diseased silkworm by Japanese biologist Shigetane Ishiwata.
• Ernst Berliner in Thuringen, Germany, then rediscovered it ten years later in a diseased caterpillar of flour moth.
• The Bt pathogen was classified in 1911 as type species Bacillus thuringiensis and remains the most widely used biopesticide to this day.
• In the early 1920s, the French began to use Bt as a biological insecticide. The first commercially available Bt product, Sporeine, appeared in France in 1938.
• In the US in the 1950s, widespread use of biopesticides began to take hold as a host of research on Bt efficacy was published.
Page 6
The Majority of Biological Applications Target Insects
2/3rd
Insecticides
Plant Health
Herbicides
Fungicides
Nematicides
Nutrients
Biologicals by Region
Latin America
Asia
Europe
North America
6
Global Ag Biologicals Industry Primarily Focused on Targeting Pest and Disease Control
Naturally Derived Chemicals are 1/3 of Biologicals Market
Other Microbial Pesticides
Biochemical
Beneficial Insects
Bt
Naturally Derived Chemicals
Inoculants
Page 7
Biopesticides Size and Growth Estimates
2005 2010 2015 2020 20250
1
2
3
4
5
6
Microbials
Biorationals
Macrobials
Source: Frost & Sullivan, Nov. 2009; BCC Research Survey 2010; CPL Business Consultants 2010
bn $Short term (<3 years) Food Chain demands Sustainable Use Directive EU New Biological product introductionsMid term (>5 years) Increasing demand for biological solutions
emerging markets (Brazil, China and India) Sustainable growth of Green Product market
in the US and EU, based on existing technologies
Long term (>10 years) Introduction of new Green technologies
• Average Market Growth (2005-2025): > 10 % Biologics, Chemicals < 3% CAGR • Biologics Market (2010-2020): 1.2 – 3.7 bn. US$
Page 8
Global Market for Biologics is Growing at > 10% p.a.
461
184
141
87
28
US
Europe
Asia-Pacific
Latin America
Rest of World
748
416
281
125 48
2005 -- $900mio 2010 - $1,600mio
$’ Millions at Retail Level
Source: Biopesticides A Global Strategic Business Report, Global Industry Analysts, Inc.
Growth across all regions; largest growth in Europe
Benefits and Barriers to Use of Biologicals
Page 10
1.2 4.1 2045 85
105
185
256
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
0
20
40
60
80
100
120
140
New Leads Launches
Cost to Discover & Develop a Synthetic
Chemical ($Mil)
Fewer New Chemicals – Higher Cost
1990 1995 2000 20090
50
100
150
# of Chemicals Screened to Find One Product (‘000) # of New Chemical
Leads vs. Product Launches
(Source: CropLife)
Source: Ag Chem New Compound Review (Vol 28) 2010
Page 11
The Case for Biopesticides in Programs
Biopesticides are effective tools for production, are renewable sustainable, offer an improved impact profile, and reduce pesticide residues.
Meeting the 3 challenges of Sustainable Agriculture• Increase productivity• Promote Food Quality• Minimize Impact
IPM
Additional benefits• Resistance Management• Harvest & Labor Management• Residue Management
Biopesticides conventional crop protection products+ = Increased efficacy, higher yield,
lower chemical load.
Page 12
CA Pest Control Advisors
Golf Course Supts.
FL Distributors CA Growers
FL Growers
(n=69) (n=40) (n=26) (n=30) (n=30)Environmentally Safe 48% 63% 54% 60% 64%
All Other Replies 35% 27% 16% 11%Operator Safety 12% 42% 8% 4% 21%
Safe/Benefits Insects 14% 8% 12% 36%Public Perception 22% 8% 15% 20% 4%
More Natural/Safe 16% 4% 8% 24% 14%Crop Safety 17% 12% 4% 25%
Organic Farming 25% 12% 16% 4%
Product Effective 13% 13% 15% 8% 4%
Don't Know/Cannot Say 3% 25% 4% 8% 4%Target Specific 9% 7%
Economic Benefits 3% 4% 4%
Reasons Biopesticides are Used
13
CA Pest Control
Advisors
Golf Course Supts.
FL Distributors CA Growers FL
Growers
(n=69) (n=40) (n=26) (n=30) (n=30)
Not as Effective 52% 42% 73% 68% 39%Higher Cost 36% 42% 31% 44% 43%
Lack of Awareness 39% 38% 18% 32% 43%
Don't Know 6% 17% 8% 24% 7%
Lack of Research 4% 21% 12% 8% 4%
Limited Availability 6% 8% 8% 4% 18%
Only Works in Specific Conditions 7% 17% 4% 7%
All Other Replies 26% 12%
Old Habits 3% 7% 4% 14%
Works Too Slowly 12% 4% 11%
Public Perception 4% 4%
Reasons Biopesticides are Not Used
Innovations in the Ag Biologicals Sector Are Driving Investment and Opportunity