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Indication:
Suspected Heart Failure With abnormal ECG or Intermediate BNP (100-400)
BNP:
Asymptomatic Murmur
Asymptomatic Cardiomegaly On CXR
Direct Access Echo RSCH
Footnote:
Please do not use open accessEcho but refer directly to consultant for:
1.Pts with symptoms and signs of CHF or very high BNP2.Pts with symtomatic heart murmurs3.Known heart failure with previous echo4.Other cardiac problems
Direct Access Echo RSCH
Drug therapy in CHF• Diuretics• ACE inhibitors• B - blockers • Spironolactone (Class III & IV
patients)• Angiotensin II receptor blockers
(Alternative to ACE I) • Hydralazine & ISDN (ACE I/ARB
intolerance or in renal failure or in Afro-Carribeans as in the AHeFT trial)
• Digoxin if still symptomatic or in AF
Dose of ACE Inhibitors in CHF
• Enalapril2.5 mg od 10-20 mg bd
• Lisinopril2.5 mg od 20-40 mg od
• Perindopril 2 mg od 4 mg od
• Ramipril 1.25-2.5 mg od 10 mg od
Initial Dose* Optimal Dose
* If there are signs of dehydration, stop diuretics for 24 hrs before initial dose of ACE inhibitor
Summary of Drug Treatment of CHF
CHF Confirmed
ACE Inhibitors (or ARBs)
Oedema
Diuretics + Consider Spironolactone in Class III/IV pts
No congestionBeta-blockers
AF
Digoxin + Warfarin
Angina
ISMN / Amlodipine
Conclusions• BNP will help exclude heart failure• ECG also useful in excluding CHF - can use
this for triage• Intermediate BNP levels can be found in
CHF/IHD/ACS, treated CHF with non-cardiac cause of dyspnoea or non-CHF with non-cardiac cause of dyspnoea including PE and pneumonia
• Echocardiography for definitive diagnosis• BNP and open access echocardiography now
available for primary care in Guildford