immunisation 2013.pdf

2013 vaccine schedules for South AfricaCompiled by Amayeza Info Services’ Vaccine Helpline: 0860 160 160

Age of child EPI schedule Age of child Private practice: Option 1

Private practice: Option 2

Age of child Private practice: Option 3

At birth OPV (0)BCG

At birth OPV (0)BCG

OPV (0)BCGHBV1

At birth OPV (0)BCG

6 weeks OPV (1)RV (1)DTaP-IPV//Hib (1)HBV (1)PCV (1)

6 weeks OPV (1)RV (1)DTaP-IPV//Hib (1)HBV (1)PCV (1)

OPV (1)RV (1)DTaP-IPV//Hib/HBV (1)PCV (1)

2 months OPV (1)RV (1)DTaP-IPV//Hib/HBV (1)PCV (1)

10 weeks DTaP-IPV//Hib (2)HBV (2)

10 weeks RV (2)2

DTaP-IPV//Hib (2)HBV (2)PCV (2)

RV (2)2

DTaP-IPV//Hib/HBV (2)PCV (2)

3 or 4 months RV (2)2


14 weeks RV (2)DTaP-IPV//Hib (3)HBV (3)PCV (2)

14 weeks RV (2 or 3)2

DTaP-IPV//Hib (3)HBV (3)PCV (3)

RV (2 or 3)2


4 or 6 months RV (2 or 3)2


9 months Measles vaccine (1)PCV (3)

9 months Measles vaccine Measles vaccine 9 months Measles vaccine

18 months DTaP-IPV//Hib (4)Measles vaccine (2)

12-15 months PCV (4)3

Chickenpox (varicella) vaccine (1)4

MMR (1) or MMRV5

Hepatitis A vaccine (repeat 6 months later)

PCV (4)3


MMR (1) or MMRV5


12-15 months PCV (4)3


MMR (1) or MMRV5


18 months DTaP-IPV//Hib (4) DTaP-IPV//Hib or DTaP-IPV//Hib/HBV (4)6

18 months DTaP-IPV//Hib or DTaP-IPV//Hib/HBV(4)6

6 years Td vaccine 5-6 years MMR (2) or MMRV5

Chickenpox (varicella) vaccine (2)DTaP or TdaP-IPV

MMR (2) or MMRV5


5-6 years MMR (2) or MMRV5


9 years HPV (from 9 years)7 HPV (from 9 years)7 9 years HPV (from 9 years)7

12 years Td vaccine 12 years TdaP-IPV TdaP-IPV 12 years TdaP-IPV

Sources for vaccines schedules• Expanded Programme of Immunisation (EPI) (April 2009).• Package inserts: Adacel Quadra®, Boostrix Tetra®, Cervarix®, Gardasil®, Infanrix-Hexa®, Pentaxim®, Prevenar®, Priorix®, Priorix Tetra®, Synflorix®, Trimovax®, Varilrix®.• Personal communication with GSK (Upper age limit of Infanrix-Hexa®). • Centers for Disease Control pink book: http://www.cdc.gov/vaccines/Pubs/pinkbook/pink-chapters.htm.

Abbreviations

(0) : Birth dose, which doesn’t count as part of primary series

(1) : First dose in a series (2) : Second dose in a series(3) : Third dose in a series(4) : Fourth dose (booster)BCG : Bacille Calmette-Guérin (tuberculosis vaccine)DTaP-IPV//Hib/HBV (hexavalent) : Diphtheria, tetanus, acellular pertussis/inactivated polio vaccine/Haemophilus influenzae type b and hepatitis B vaccine DTaP-IPV//Hib (pentavalent) : Diphtheria, tetanus, acellular pertussis/inactivated polio vaccine and Haemophilus influenzae type b vaccineEPI : Expanded Programme of ImmunisationHBV : Hepatitis B vaccineHPV : Human papillomavirus vaccineMMR : Measles, mumps and rubella vaccineMMRV : Measles, mumps, rubella and varicella vaccineOPV : Oral polio vaccinePCV : Pneumococcal conjugated vaccineRV : Rotavirus vaccineTdap-IPV (quadrivalent) : Tetanus and reduced amount of diphtheria vaccine with acellular pertussis and inactivated polio vaccine. Td vaccine : Tetanus and reduced amount of

diphtheria vaccine

Notes (superscripted numbers)

1. If the hexavalent vaccine (Infanrix-Hexa®) is given according to the EPI schedule (6, 10 and 14 weeks), a birth dose of HBV (not routinely given in South Africa) is required.

2. If pentavalent RV is given, three doses are required, at 6, 10 and 14 weeks. If monovalent vaccine is given, only two doses are required, at 6 and 14 weeks.

3. When Synflorix® is given, the fourth dose can be given from 9.5 months, provided it has been six months since the last dose.

4. Chickenpox (varicella) vaccine can be given at any time from 9 months of age, but is probably most effective if given after the age of 12 months. If not given on the same day as measles vaccines, the vaccines must be separated by at least one month. Varicella vaccine can now be given in combination with MMR as MMRV.

5. MMRV is an option if varicella vaccine has not been given yet. MMRV can be given in place of MMR and varicella vaccines.

6. A booster of HBV is not routinely recommended in South Africa.

7. HPV quadrivalent vaccine can be given to boys and girls; the course consists of three doses, at 0, 2 and 6 months. HPV bivalent vaccine can be given to girls only; the course consists of three doses, at 0, 1 and 6 months.

Paediatric vaccines available for other situations

• Hiberix® [Hib (Haemophilus influenzae type b)]: Up to 5 years of age. • Infanrix® [DTaP (diphtheria, tetanus, acellular pertussis)]: Up to 7 years of age.• Twinrix® (hepatitis A and B).

Vaccine trade names

Vaccine Trade name Age groupBCG BCG® Usually at birth only

In certain cases, up to 1 yearChickenpox Varilrix® 9 months and olderDTaP-IPV//Hib/HBV

Infanrix-Hexa® 8 weeks to 2 years

DTaP-IPV/Hibº Pentaxim® 6 weeks to 2 yearsHepatitis A Avaxim 80®

Havrix Junior®1–15 years

Hepatitis B (HBV) Heberbiovac HB®Euvax®Engerix-B®

Birth to adulthoodDose according to age

HPV Gardasil® (quadrivalent)

9-26 years

Cervarix® (bivalent) 9 years and olderMeasles Rouvax® 9 months and olderMMR Trimovax®

Priorix®1 year to adulthood

MMRV Priorix Tetra® 9 months to 12 yearsOPV OPV-Merieux®

Polioral®Birth to adulthoodNot generally recommended in adulthood, because of vaccine-associated paralytic polio (VAPP)

PCV Prevenar-13® 6 weeks to 5 yearsSynflorix® 6 weeks to 2 years

RV Rotarix® First dose from 6 weeks, second dose before 24 weeks

Rotateq® First dose from 6 weeks, last dose before 32 weeks

TdaP-IPV Adacel Quadra® From 3 yearsBoostrix Tetra® From 4 years

Td Diftavax® 6 years and older

Documents

immunisation 2013.pdf