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IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY Ü ABOUT IMBA IMBA – Instute of Molecular Biotechnology is one of the leading biomedical research instutes in Europe focusing on cung-edge funconal genomics and stem cell technologies. IMBA is located at the Vienna BioCenter, the vibrant cluster of universies, research instutes and biotech companies in Austria. IMBA is a basic research instute of the Austrian Academy of Sciences, the leading naonal sponsor of non-university academic research. Ü ABOUT VIENNA BIOCENTER The Vienna BioCenter (VBC) is a leading life sciences locaon in Europe, offering an extraordinary combinaon of research, educaon and business on a single campus. About 1,700 employees, including more than 1,300 scienst from 70 naons create a highly dynamic environment of internaonal standards. www.viennabiocenter.org EDUCATION >1,550 Students BUSINESS 17 Biotech companies RESEARCH 88 Research groups

IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGYIMBA – Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional

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Page 1: IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGYIMBA – Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional

IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY

IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY

ÜABOUT IMBA

IMBA – Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional genomics and stem cell technologies. IMBA is located at the Vienna BioCenter, the vibrant cluster of universities, research institutes and biotech companies in Austria. IMBA is a basic research institute of the Austrian Academy of Sciences, the leading national sponsor of non-university academic research.

ÜABOUT VIENNA BIOCENTER

The Vienna BioCenter (VBC) is a leading life sciences location in Europe, offering an extraordinary combination of research, education and business on a single campus. About 1,700 employees, including more than 1,300 scientist from 70 nations create a highly dynamic environment of international standards.www.viennabiocenter.org

EDU

CATI

ON

> 1,550 Students

BUSI

NES

S

17 Biotech companies

RESE

ARCH 88

Research groups

Page 2: IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGYIMBA – Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional

IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY

Ü SCIENTIFIC EXCELLENCE

PUBLICATIONS*

Ü EDUCATION & TRAINING

VBC Summer SchoolVBC PhD ProgrammeComprehensive seminar programme with top-notch international speakerswww.training.vbc.ac.at

ERC GRANTS*Starting 5Advanced 4Consolidator 2Proof of Concept 2

EMBO MEMBERSHIPS* EMBO full members 4EMBO YIPs (active) 2

ÜRESEARCH GROUPS

Mechanism and biology of RNA silencing. Post-transcriptional gene regulation, RNA biochemistry, RNP enzymology, RNA modifications, small non-coding RNAs

Transposon silencing & heterochromatin formation by small RNAs. Transposons, piRNAs, heterochromatin, epigenetics, small RNAs

Assembly and function of the cell division machinery. Mitosis, chromosomes, cell organelles, high-content screening, computer vision, biophysics

Mechanisms of epigenetic memory.Epigenetics, chromatin, development, polycomb, histone modifications

Functional genomics in embryonic stem cells. Haploid, screen, CRISPR/Cas, embryonic stem cell, cell fate

Linear ubiquitination in inflammation, cell death and autophagy. Ubiquitin signal, E3 ligase, immune responses, cell death, autophagy

30% of all IMBA publications are in the Top 10% most cited articles in their respective fields Source: InCites dataset updated Aug 31, 2018

>950

Publications since IMBA´s foundation in 2003

*as of 8/2018

STEFAN AMERES

JULIUS BRENNECKE

DANIEL GERLICH

OLIVER BELL

ULRICH ELLING

FUMIYO IKEDA

Page 3: IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGYIMBA – Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional

IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY

Scientific DirectorBrain development and disease. Stem cell, brain, organoids, cancer

Molecular control of human organogenesis. Organogenesis, human pluripotent stem cells, mesoderm, cardiac, adipose, patterning

Chromatin reprogramming in totipotent stem cells. Totipotency, stem cells, chromatin organization, epigenetic reprogramming, zygotes, oocytes

Homeostatic regulation of adult stem cells. Adult stem cells, organoids, genetics, E3 ubiquitin ligases, cancer

Founding Director (2002 - 2018)Modeling human disease. Embryonic stem cells, organoids, development, cancer, disease, mouse models

Systemic regulation of adult neurogenesis. Brain, stem cells, niche, metabolism, memory, emotions

Ü STAFF

JÜRGEN KNOBLICH

SASHA MENDJAN

KIKUË TACHIBANA

BON-KYOUNG KOO

JOSEF PENNINGER

NOELIA URBÁN

male50%

female50%

Gender Distribution* Nationalities*

38total

North America4

Europe193

Africa3

Asia18

South America1

Principal Investigators12

Postdocs37

PhD Students45

Scientific Service58

Technicians20

Administration31

Master/Diploma Students16

Functions*

219employees

*as of 6/2018

Page 4: IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGYIMBA – Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional

IMBA – INSTITUTE OF MOLECULAR BIOTECHNOLOGY

WWW.IMBA.OEAW.AC.AT DR. BOHR-GASSE 3 | VIENNA BIOCENTER | 1030 VIENNA, AUSTRIA | T: +43 1 79044 | F: +43 1 79044-100IBAN: AT22 1100 0012 7034 1900 | BIC: BKAUATWW

Ü SCIENTIFIC ADVISORY BOARD

Elaine Fuchs, Rockefeller University / Howard Hughes Medical Institute, New York, USA

Gregory Hannon, Cold Spring Harbor Laborartory / Howard Hughes Medical Institute, New York, USA; Cancer Research UK, University of Cambridge, UK

Eric Kandel, Columbia University, New York, USA

Guido Kroemer, Cordeliers Research Center University of Paris Descartes, Paris, France

Maria Leptin, Institute of Genetics, University Cologne, Germany

Gary Ruvkun, Department of Genetics / Harvard Medical School, Boston, USA

Fiona Watt, Centre for Stem Cells and Regenerative Medicine, King’s College London, UK

Ü SCIENTIFIC FACILITIES

IMBA is committed to the success of its research groups. We provide strong administrative and scientific support that includes a broad array of cutting-edge services and facilities. Facilities that are available to IMBA researchers include:

• Bioinformatics• BioOptics• Electron Microscopy• Metabolomics• Next Generation Sequencing• Protein Chemistry• Stem Cell Core Facility

www.imba.oeaw.ac.at/scientific-facilities/www.vbcf.ac.at

Ü BUDGET 2018

ÜMORE INFORMATION

www.imba.oeaw.ac.at

Others (incl. private funding)7%

Austrian Academy of Sciences48%

Research Grants28%

Revenues17%

35Mio €