IFDEA Dentin Hypersensitivity Educational Teaching Resource

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    DENTIN HYPERSENSITIVITY

    Physiology, Etiology, Epidemiology, Diagnosis,

    and Treatment

    Reviewed by:

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    Dentin Hypersensitivity

    After viewing this lecture, attendees should be able to:

    describe the oral anatomy as it relates to dentin hypersensitivity.

    discuss the etiology and physiologic mechanism of dentin hypersensitivity.

    describe the prevalence and epidemiology of dentin hypersensitivity.

    describe the diagnosis and management of dentin hypersensitivity.

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    Dentin Hypersensitivity

    Dentin hypersensitivity is best defined as a short, sharp, pain

    arising from exposed dentin in response to stimulitypically thermal,

    evaporative, tactile, osmotic or chemical, and which

    cannot be ascribed to any other form of defect or pathology.1

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    Enamel

    Dentin

    Cementum

    Dental Pulp

    The 4 main dental tissues:

    Enamel

    Dentin

    Cementum

    Dental Pulp

    Oral Anatomy:

    Dental Tissues

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    Anatomic Crown

    Anatomic Root

    Pulp Chamber

    The 3 parts of a tooth:

    Anatomic Crown

    Anatomic Root

    PulpChamber

    Oral Anatomy:

    Dental Tissues

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    Oral Anatomy:

    Dental Tissues

    Enamel

    Dentin

    Cementum

    Dental Pulp

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    Oral Anatomy:

    Dentinal Tubules

    Presence of tubules renders

    dentin permeable to fluid

    movement Number of tubules per unit

    area varies

    Dentinal tubules are conical

    Dentin

    Pulp

    Tubule

    Fluid Nerve Fibers

    OdontoblastCell

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    Dentin Hypersensitivity: Physiology

    The most widely accepted mechanism of action for dentin hypersensitivity isthe Hydrodynamic Theory, which was first proposed by Gysi in 1900 and

    validated by Brannstrom in 1996.2

    Mechanism of Dentin Hypersensitivity

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    Dentin Hypersensitivity: Physiology

    There are two essential elements of the hydrodynamic mechanism:2

    Fluid flow through dentinal tubules

    Pulpal sensory nerves

    Mechanism of Dentin Hypersensitivity

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    Dentin

    Hypersensitivity:Physiology

    Two processes required:3

    dentin must be exposed

    dentin tubules must be open to:

    dentin surface

    patent to the pulp

    Hydrodynamic Theory

    Enamel

    ExposedDentin

    RecedingGingiva

    Tubules

    Odontoblast

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    Dentin

    Hypersensitivity:Physiology

    Trigger stimuli include:3

    Thermal

    Hot

    Cold

    Tactile

    Evaporative

    Osmotic

    Hydrodynamic Theory

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    Dentin

    Hypersensitivity:Physiology

    The true physiologic stimulus isthe inward or outward fluid shifts,

    not the actual trigger.4

    Hydrodynamic Theory

    Fluid-filledTubules

    Dentin NerveFibers

    OdontoblastCell

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    Dentin

    Hypersensitivity:Etiology

    The most important factor in the

    etiology of dentin hypersensitivity isexposed dentin.5,6

    Hydrodynamic Theory

    The result of gingival recession(exposure of root surfaces)

    The result of loss of enamel from toothwear or trauma

    Loss of cementum Removal or absence of a smear layer

    RecedingGingiva

    Tooth

    Wear

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    Dentin Hypersensitivity: Etiology

    Gingival Recession is caused by:7

    Physiologic factors Hormonal fluctuations

    Poor nutrition

    Aging

    Periodontal diseases Gingivitis

    Periodontitis

    Periodontal therapy Scaling and root planning Surgery

    Restoration margins

    Chronic trauma Oral hygiene (toothbrushing)

    Habits (tobacco smoking & chewing)

    Predisposing anatomic factors Thin gingiva

    Prominent roots

    Dehiscences

    Fenestrations

    Frenum pulls

    Roots moved outside alveolarhousing by orthodontics

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    Physical Loss

    Abrasionmechanical

    Attritiontooth/tooth

    Abfractionlesions

    Chemical dissolution

    Erosion

    -Extrinsic acids

    -Intrinsic acids

    Multifactorial etiology

    Erosion, abrasion, attrition,abfraction

    Tooth Wear can occur as a result of:3,8

    Dentin Hypersensitivity: Etiology

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    Dentin

    Hypersensitivity:Etiology

    Not all exposed dentin is sensitive3

    Dentinal Tubules

    Surface appearance

    Open/patent tubules

    Greater number of tubules

    Tubules larger in diameter

    Absence of smear layer

    Tubules open from tooth wear

    Characteristics of Sensitive Dentin:

    Dentin

    Tooth

    Wear

    RecedingGingiva

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    Dentin Hypersensitivity: Etiology

    Dentin becomes exposed through enamel

    or cementum loss and/or gingivalrecession

    Opening of tubules by removal of the

    smear layer initiates the lesion

    Disturbed flow stimulates

    A-beta (A-) and some A-delta (A-)nerve fibers

    Understanding Dentin Hypersensitivity Pain4

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    Dentin Hypersensitivity: Etiology

    Aggressive toothbrushing

    Periodontal diseases

    Periodontal therapy

    Tooth whitening/bleaching

    Understanding Dentin Hypersensitivity Pain

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    Dentin

    Hypersensitivity:Etiology

    Erosionacts alone, or incombination with abrasion tocause enamel loss

    Extrinsic/intrinsic acids causesurface softening of enamel whichtakes hours to re-harden andresults in greater susceptibility tophysical insult

    Understanding Dentin Hypersensitivity Pain9

    3. Strassler HE, Drisko CL, Alexander DC.

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    Incidence: 15% (4% to 57%)

    Age range: 1570+ years

    Peak incidence: 2040 years

    Gender: Female > Males

    Global Prevalence3

    Dentin

    Hypersensitivity:Epidemiology

    Pain or discomfort caused by cold, hot, s weet, sour, foods/drinks or tooth brushing.

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    Dentin

    Hypersensitivity:Epidemiology

    Teeth:Canines (cuspids) and premolars

    (bicuspids)

    Sites:Buccal cervical regions

    Most Commonly Found3

    Canine Premolar

    Canine

    In: Pashley DH, Tay FR, Haywood VB, et al. DentinHypersensitivity: Consensus-Based Recommendationsfor the Diagnosis and Management of DentinHypersensitivity.

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    Frequency of Dentate Adults whoResponded Positively to Having or Ever Having

    Sensitive Teeth

    Dentin Hypersensitivity: Epidemiology

    In a multi-national survey

    conducted with 11,000 adults in

    2002, 48% of participants said at

    some point they had consulted a

    dentist due to sensitive teeth.10,11

    22

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    Dentin Hypersensitivity: Epidemiology

    Dietary changes

    Acidic food/drinks

    Periodontal procedures

    Cosmetic treatments

    Bleaching/whitening12-14

    Restorative

    AgingRetain natural teeth

    There are a number of factors that may contribute to an

    increased prevalence of dentin hypersensitivity:3

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    Dentin Hypersensitivity: Management

    Differential diagnosis

    Exclude or treat other causes

    of dentin pain

    Identify etiological factors

    Prevent, remove or modify

    etiological factors

    Management/treatment

    Management begins with patient education and modification of risk factors15

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    Dentin Hypersensitivity: Management/Diagnosis

    Complete History

    Sign and symptoms

    Intensity

    Frequency and duration

    Dietary changes

    Other related events

    Clinical Examination

    Visual assessment

    Physical assessment

    Dental explorer

    (probe): tactile stimulus

    Periodontal probe

    Depth of periodontal

    pocket

    Percussion testing Response to cold air

    Dentin Hypersensitivity is a diagnosis of exclusion

    Radiographic examination

    Rule out periapical lesions

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    Differential Diagnosis

    Cracked tooth syndrome

    Fractured restoration

    Chipped teeth

    Dental caries

    Periodontal disease

    Post-restorative sensitivity

    Marginal leakage

    Pulpitis

    Palatogingival groove Bleaching sensitivity

    Needs to rule out:15

    Non-Odontogenic Origin

    Musculoskeletal

    Neuropathic

    Neurovascular Inflammatory (sinusitis)

    Systemic (cardiac, herpes,

    zoster, sickle cell anemia,

    neoplasm)

    Psychogenic

    Referred pain

    Dentin Hypersensitivity: Management/Diagnosis

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    Tooth sensitivity is one of the most common forms of dental pain Usually occurs on the side opposite the dominant hand

    The buccal cervical sites on the canine and pre-molars are the most common

    sites for tooth sensitivity

    Incidences3

    Dentin Hypersensitivity: Management/Diagnosis

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    Dentin Hypersensitivity:Management/Diagnosis

    Root sensitivity is typically a

    result of gingival recession that

    may be compounded by tooth

    wear

    Sensitivity in the crown may be

    caused by some form or

    combination of factors attributed

    to tooth wear

    Tooth Wear3

    RecedingGingiva

    DentinWear

    EnamelWear

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    All forms of vital tooth bleaching are associated with some level of sensitivity

    Bleaching sensitivity is caused by the easy passage of hydrogen peroxide and

    urea through the intact enamel, through the dentin in the interstitial spaces into

    the pulp within 5 to 15 minutes16

    Tooth Whitening/Bleaching16

    Dentin Hypersensitivity: Management/Diagnosis

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    Prevention and Treatment of Bleaching Hypersensitivity

    16. Pashley DH, Tay FR, Haywood VB, et al.

    Dentin Hypersensitivity: Management/Diagnosis

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    Dentin Hypersensitivity:Management/Diagnosis

    Cold beverages

    Eating cold food

    Breathing cold air

    Toothbrushing

    Improper dental floss use

    Eating sour/acid food

    Eating sweet/sugary liquids

    and foods Bleaching/whitening procedures

    Occurrence of pain:3

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    Thermalpain in response to cold or hot

    Evaporativeblowing air on the tooth surface

    Tactilepain in response to touch

    Osmoticpain in response to sugar/acid

    Dental treatmentthis type of sensitivity is transient and will resolvewith removal of treatment or over time

    Dentin Hypersensitivity: Management/DiagnosisSensitivity may occur in response to various stimuli:3

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    Dentin Hypersensitivity:

    Management/Etiological Factors

    Tooth Wear/Erosion:

    Use fluoride-rich dentifrice

    Behavior modification

    Decrease abrasive forces

    Application of topical fluoride

    Enhance the defense mechanisms of the body

    Provide nutritional counseling

    Management of Pre-disposing Factors17

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    Dentin Hypersensitivity:

    Management/Etiological Factors

    Gingival Recession:

    Correct toothbrushing technique

    Plaque control

    Avoidance of harmful habits

    Periodontal disease management

    Replacement of restorations with defective margins

    Smoking cessation

    Management of Pre-disposing Factors17

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    Dentin Hypersensitivity:Treatment

    Obturate tubules or alter fluidflow in dentinal tubules

    Modify or block pulpal nerve

    response

    Management of Dentin Hypersensitivity3,4

    KNO3

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    CHEMICAL AGENTS18

    Nerve Inactivators

    Potassium salt (nitrate-

    KNO3)

    Tubule Obtundants

    Strontium chloride

    Calcium hydroxide

    Fluorides

    Sodium citrate

    Potassium oxalate

    Iontophoresis with NaF

    Management of Dentin Hypersensitivity

    Protein Precipitators

    Strontium chloride

    Silver nitrate

    Formaldehyde

    Dentin Hypersensitivity: Treatment

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    PHYSICAL AGENTS18

    Dentin Hypersensitivity: TreatmentManagement of Dentin Hypersensitivity

    Composite resins

    Bonding agents

    Sealants

    Glass-ionomer cements

    Varnishes

    Soft tissue grafts Lasers

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    Dentin Hypersensitivity: Treatment

    At-home treatmentspatient applied

    Anti-sensitivity dentifrice

    Fluoride-based gels

    Rinses

    Options for Treatment19

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    Dentin Hypersensitivity: Treatment

    In-office by dental professional

    Chemicals (oxalates)

    Physical agents

    Restorations

    Endodontic (root canal)

    Tooth extraction

    Options for Treatment19

    (listed as least invasive to most)

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    Dentin Hypersensitivity: the common cold of dentistry.3

    Dentin Hypersensitivity

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    Dentin HypersensitivityReferences

    1. Ajcharanukul O, Kraivaphan P, Wanachantarak S, et al. Effects of potassium ions on dentin sensitivity in man.Arch Oral Biol. 2007;52(7);632-639.

    2. Matthews B, Vongsavan N. Interaction between neural and hydrodynamic mechanisms in dentine and pulp.Arch Oral Biol. 1994:39(Suppl):87S-95S.

    3. Strassler HE, Drisko CL, Alexander DC. Dentin hypersensitivity: its inter-relationship to gingival recession and acid erosion.Inside Dentistry. 2008;29(5

    Special Issue):3-8.

    4. Dentin hypersensitivity: current state of the art and science. In: Pashley DH, Tay FR, Haywood VB, et al. Dentin Hypersensitivity: Consensus-Based

    Recommendations for the Diagnosis and Management of Dentin Hypersensitivity. Inside Dentistry. 2008;4(9 Special Issue):8-18.

    5. Watson PJ. Gingival recession.J Dent. 1984;12(1):29-35.

    6. Smith RG. Gingival recession. Reappraisal of an enigmatic condition and a new index for monitoring.J Clin Periodontol. 1997;24(3):201-205.

    7. Dentin hypersensitivity and gingival recession. In: Pashley DH, Tay FR, Haywood VB, et al. Dentin Hypersensitivity: Consensus-Based

    Recommendations for the Diagnosis and Management of Dentin Hypersensitivity. Inside Dentistry. 2008;4(9 Special Issue):19-24.

    8. Imfeld T. Dental erosion. Definition, classification and links.Eur J Oral Sci. 1996;104(2 (Pt 2)):151-155.

    9. ten Cate JM, Imfeld T. Dental erosion. Summary.Eur J Oral Sci. 1996;104(2 (Pt 2)):241-244.

    10. Addy, Martin, Dentin hypersensitivity: new perspective on an old problem. Int Dent J. 2002;52:367-375.

    11. Drisko, CH. Dentin hypersensitivitydental hygiene and periodontal considerations.Int Dent J. 2002;52;385-393.

    12. Auschill TM, Hellwig E, Schmidate S, et al. Efficacy, side-effects and patients acceptance of different bleaching techniques (OTC, in-office, at home).

    Oper Dent. 2005;30(2):155-163.

    13. Broening WD, Blalock JS, Fraizer KB, et al. Duration and timing of sensitivity related to bleaching.J Esthet Restor Dent. 2007; 19(5): 256-264

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    Dentin HypersensitivityReferences

    14. Haywood VB, Leonard R, Nelson CF, et al. Effectiveness, side effects and long-term status of nightguard vital bleaching.J Am Dent Assoc.

    1994;125(9):1219-1226.

    15. Dentin hypersensitivity: consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. In: Pashley DH, Tay FR,

    Haywood VB, et al. Dentin Hypersensitivity: Consensus-Based Recommendations for the Diagnosis and Management of Dentin Hypersensitivity.Inside

    Dentistry. 2008;4(9 Special Issue):1-7.

    16. Considerations for managing bleaching sensitivity. In: Pashley DH, Tay FR, Haywood VB, et al. Dentin Hypersensitivity: Consensus-Based

    Recommendations for the Diagnosis and Management of Dentin Hypersensitivity. Inside Dentistry. 2008;4(9 Special Issue):25-31.

    17. Lussi A, Hellwig E. Risk assessment and preventative measures. In: Lussi A, ed.Dental Erosion: From Diagnosis to Therapy. Basel, Switzerland:

    Karger; 2006:190-199. Whitford GM.Monographs in Oral Science; vol 20.

    18. Dentin Hypersensitivity: Etiology, Diagnosis and Successful Management. Advancements in Oral Health Educational Module.19. Canadian Advisory Board on Dentin Hypersensitivity. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity.

    J Can Dent Assoc. 2003;69(4):221-226.

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    Dentin Hypersensitivity

    This IFDEA Educational Teaching Resource was

    underwritten by an unrestricted grant from: