www.SpectraCell.com

© 2013 SpectraCell Laboratories, Inc. Doc 369 11.13

Functional Vitamin, mineral and antioxidant assessment

Houston, Texas

800.227.LABS (5227)

Research proves that nutrients work synergistically so that the status of one nutrient typically impacts the status of other nutrients. Every vitamin and mineral should be evaluated within the context of others. This guide summarizes years of clinical experience with micronutrient testing.

HOW TO USE THIS GUIDE

Section: MONITOR THE FOLLOWING For each nutrient tested, the “Monitor the Following” section lists other nutrients most commonly affected by a deficiency of the main nutrient listed. For example, if a patient shows deficiency in thiamin (vitamin B1), we suggest that you also pay specific attention to levels of magnesium and pyridoxine (vitamin B6). Although a deficiency may not (yet) exist in the nutrients listed under “Monitor the Following”, we commonly see these deficiencies develop if a deficiency of thiamin (vitamin B1) is not corrected.

Section: PATIENT PROFILE These are the most common clinical presentations that occur when a deficiency of the referenced nutrient exists. For example, a patient who has a thiamin deficiency often presents with neuropathies, depression, myalgia, cardiomyopathies or takes diuretics and/or eats a high carbohydrate diet. Although this list is not exhaustive, it summarizes the most common clinical conditions seen by physicians using micronutrient testing.

Micronutrient Testing - Clinician Reference Guide

Director of Clinical Nutrition and Education“I’ve used SpectraCell’s micronutrient tests in my practice for over a decade. Nutritional deficiencies lie at the heart of so many conditions I see, and unless they are corrected, a patient never really resolves their health issues on a permanent level. In many cases, these patients have struggled for years with symptoms that disappear when their nutrient deficiencies are corrected and I’m thrilled to pass on my clinical experience.”

-Ron Grabowski, RD, DC

Email: Education@SpectraCell.com

Consults are Available by Appointment

or visit us online at www.SpectraCell.com/MNTconsult

Vitamin B1 (thiamin)

Monitor the Following

£ Magnesium (phosphorylation) £ Vitamin B6 (pyrodoxine)

Patient Profile

w High carbohydrate consumptionw Diureticsw Neuropathiesw Depressionw MyalgiawCardiomyopathies

Vitamin B2 (riBoFlaVin)

Monitor the following£ Glutathione £ Synergistic with Vitamin B3 (niacin) & Vitamin B6 (pyrodoxine)£ Consider with abnormal antioxidant status£ Homocysteine

Patient Profile

w Migraine headachesw Anemia (iron)w Cheilosis

© 2013 SpectraCell Laboratories, Inc.11.13

Vitamin B3 (niacin)

Monitor the following

£ Glucose insulin interaction£ Homocysteine£ Correlate Vitamin B12 (cobalamin) & folate

Patient Profile

w Diabetesw Coronary artery disease

Vitamin B6 (Pyridoxine)

Monitor the following

£ Vitamin B3 (niacin)£ Vitamin B2 (riboflavin)£ Vitamin B6 (pyridoxine)

Patient ProfilewCarpal tunnel syndromewPremenstrual syndromewDepressionwCoronary artery diseasewHigh protein dietwAnemiawNeuropathywCeliac disease

Vitamin B12 (coBalamin)

Monitor the following£ Folate £ Vitamin B6 (pyridoxine)£ Choline£ Serine£ Homocysteine levels

Patient ProfilewCarpal tunnel syndromewAnemiawDepressionwNeuropathieswDiabetes mellituswCoronary artery diseasewNeurodegenerative diseaseswInflammatory bowel diseasewMigraine headacheswFatigue

FolateMonitor the following

£ Vitamin B12 (cobalamin) and Vitamin B6 (pyridoxine)£ Homocysteine£ Serine£ Choline£ Zinc

Patient Profile

wNeuropathieswAnemiawCoronary artery diseasewRestless leg syndromewInflammatory bowel disease wColon cancer

Vitamin B5 (Pantothenate)

Monitor the following£ Vitamin B12 (cobalamin)£ Vitamin B2 (riboflavin)£ Biotin£ Cholesterol£ Coenzyme Q10£ Carnitine

Patient ProfilewStresswMalabsorptionwDry skinwNeuropathieswBurning feet syndromewDepressionwImmunosuppression •Allergies •Frequentillness

BiotinMonitor the following£ Vitamin B5 (pantothenate)£ Essential fatty acids£ Oleic acid

Patient ProfilewMyalgiawDry skinwMalabsorptionwNeuropathieswAbnormal florawAntibiotic usage

serineMonitor the following£ Folate£ Vitamin B6 (pyridoxine)£ Vitamin B2 (cobalamin)£ Vitamin B5 (pantothenate)£ Vitamin B1 (thiamin)

Patient ProfilewNeuropathieswNeurodegenerative diseases

GlutamineMonitor the following£ Glutathione£ Vitamin B2 (riboflavin)£ Cysteine

Patient ProfilewAthleteswChemotherapywGastrointestinal conditionsw Poor antioxidant status

asParaGineMonitor the following£ Vitamin B5 (pantothenate)£ Vitamin C£ Zinc£ Vitamin A£ Antioxidant status

Patient ProfilewImmunosuppression •Allergies •Infections(chronic)wNeuropathies

cholineMonitor the following£ Vitamin B5 (pantothenate)£ Glutamine£ Vitamin B12 (cobalamin)£ Folate£ Essential fatty acids£ Biotin£ Fat absorption£ Homocysteine

Patient ProfilewNeuropathieswCoronary artery diseasewAthletes (spasms/fatigue)wBiliary abnormalities

inositolMonitor the following£ Calcium£ Vitamin B6 (pyridoxine)£ Vitamin B12 (cobalamin)£ Vitamin B1 (thiamin)

Patient ProfilewBone mineral density •Osteopenia •OsteoporosiswHormone abnormalitieswDepressionwDiabetes mellitus

carnitineMonitor the following£ Ammonia£ Magnesium£ Coenzyme Q10£ Vitamin B5 (pantothenate)

Patient ProfilewMuscle fatiguewChronic fatigue immune deficiency syndromewFibromyalgiawCarbohydrate cravingwFat metabolism abnormalities

oleic acidMonitor the following£ Biotin£ Vitamin B5 (pantothenate)

Patient ProfilewDry skinwFat malabsorptionwCoronary artery disease

Vitamin dMonitor the following£ Calcium£ Magnesium£ Zinc£ Vitamin B3 (niacin)£ Chromium£ Glucose/insulin interaction£ Spectrox

Patient ProfilewMyalgiawBone mineral density abnormalwDiabetes mellituswImmunodeficiencywCancerwObesitywLiver dysfunctionwRenal dysfunctionwFat malabsorption

Vitamin aMonitor the following£ Zinc£ Vitamin D£ Vitamin E

Patient ProfilewGastrointestinal conditionswUpper respiratory infectionswSinusitiswViral infections

Glucose-insulin interaction

Monitor the following£ Zinc£ Vitamin B3 (niacin)£ Magnesium£ Vitamin D£ Chromium£ Lipoic acid

Patient ProfilewDiabetes mellituswPremenstrual syndromewHeadacheswMetabolic syndromewHypoglycemia

Fructose sensitiVity

Monitor the following£ Copper£ Glucose-insulin interaction£ Magnesium

Patient ProfilewElevated triglycerideswElevated uric acidwCarbohydrate cravingswPremenstrual syndromewHypoglycemiawDiabetes mellituswCoronary artery diseasewSoft drink consumption

chromiumMonitor the following£ Zinc£ Vitamin D£ Vitamin B3 (Niacin)£ Magnesium

Patient ProfilewRefined carbohydrateswDiabetes mellituswHypoglycemiawHeadaches

ZincMonitor the following£ Calcium£ Glucose-insulin interaction£ Fructose sensitivity£ Magnesium£ Vitamin D£ Chromium£ Vitamin B3 (niacin)

Patient ProfilewDiabetes mellituswImmunosuppressionwPoor wound healingwAnemiawOsteoporosis/OsteopeniawPregnancywHypothyroidism

calciumMonitor the following£ Magnesium£ Vitamin D£ Inositol£ Zinc

Patient ProfilewBone mineral density abnormalwHeadacheswMyalgia/muscle crampswFat malabsorptionwColon cancer

coPPerMonitor the following£ Zinc£ Fructose sensitivity£ Cholesterol£ Triglycerides£ Spectrox

Patient ProfilewNeuropathywFructose intake (high)wAnemia (iron)wUric acid (elevated)

maGnesiumMonitor the following£ Vitamin B1 (thiamin)£ Coenzyme Q10£ Calcium£ Zinc£ Vitamin B6 (pyridoxine)

Patient ProfilewDiabeteswPremenstrual syndromewCoronary artery diseasewHypoglycemiawHeadacheswMuscle spasmswCravingswStresswDiureticswHypertension

GlutathioneMonitor the following£ Vitamin B2 (riboflavin)£ Glutamine£ Zinc£ Vitamin E£ Selenium£ Lipoic acid£ Cysteine£ Vitamin D£ Coenzyme Q10

Patient ProfilewCancerwSmokerwAthletewDiabeteswCoronary artery diseasewImmunosuppressionwNeurodegenerative diseases

cysteineMonitor the following£ Glutamine£ Vitamin B2 (riboflavin)£ Glutathione£ Vitamin E£ Selenium£ Coenzyme Q10£ Lipoic acid£ Vitamin D£ Zinc

Patient ProfilewDiabeteswAsthmawCancerwCoronary artery diseasewImmunosuppression

coenZymeQ10Monitor the following£ Magnesium£ Carnitine£ Vitamin B5 (pantothenate)£ Vitamin E£ Lipoic acid£ Glutathione£ Glutamine£ Selenium£ Vitamin D£ Cysteine£ Zinc£ Vitamin B2 (riboflavin)

Patient ProfilewCoronary artery diseasewHpertensionwNeurodegenerative diseaseswMyalgiawChronic fatigue immune deficiency syndromewMigraines

seleniumMonitor the following£ Vitamin E£ Lipoic acid£ Cysteine£ Glutathione£ Glutamine£ Vitamin D£ Zinc£ Coenzyme Q10£ Vitamin B2 (riboflavin)

Patient ProfilewCoronary artery diseasewCancerwCeliac diseasewNeurodegenerative diseaseswInfections (chronic)wThyroid dysfunctionwHigh density lipoprotein/Low density lipoprotein ratio

Vitamin eMonitor the following£ Selenium£ Cysteine£ Glutathione£ Glutamine£ Zinc£ Lipoic acid£ Coenzyme Q10£ Vitamin D£ Vitamin B2 (riboflavin)

Patient ProfilewCoronary artery diseasewNeurodegenerative diseaseswCancerwFibrocystic breast diseasewPremenstrual syndromewFat malabsorptionwNeuropathies

alPha liPoic acid

Monitor the following£ Vitamin E£ Vitamin D£ Glutathione£ Glutamine£ Cysteine£ Coenzyme Q10£ Zinc£ Selenium£ Vitamin B2 (riboflavin)

Patient ProfilewDiabeteswNeuropathieswMyalgiawFat malabsorption

Vitamin cMonitor the following£ Cholesterol£ Spectrox£ Calcium£ Zinc£ Copper

Patient ProfilewStresswAthletewGallstoneswSurgerywImmunodeficiency

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