HK VTC 25-11-2006 Medicinal Mushrooms

8/9/2019 HK VTC 25-11-2006 Medicinal Mushrooms

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HK VTC 26-11-06 1

Medicinal Mushrooms

Georges M. Halpern, MD, PhD

Distinguished Professor of Pharmaceutical Sciences

Hong Kong Polytechnic University

[email protected]

mailto:[email protected]:[email protected]


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Medicinal Mushrooms as Immunoregulators

An immunoregulator is any substance that can quiet or

activate the immune system, depending on

circumstances.

Medicinal mushrooms can help the immune system stay

wide awake and strike the perfect balance between

overactivity and sluggishness.


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Polysaccharides and Beta Glucans

Beta Glucans are a type of polysaccharide found inmushrooms that give mushrooms some medicinalproperties.

Beta Glucans are huge molecules

Beta Glucans are decoys that make the body believe it isbeing invaded by a microbe or a foreign cell

Beta Glucans bind to certain receptors on the surface ofmacrophages and other white blood cells

Beta Glucans have been shown to stimulate the production ofsome cytokines

Prevention of asthma


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Medicinal Mushrooms as Adaptogens

Adaptogens are substances that help the bodyadapt during times of stress

tress and !ortisol

"ffects of adaptogens on stress


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#erpenoids in Mushrooms

anti$infectious

anti$inflammatory


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Medicinal Mushrooms and Prebiotics

Mushrooms form a class above many otherprebiotics

timulate M cells in the lining of the intestine


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Ganoderma lucidum %&eishi, 'ing(hi)Bitter (terpenoids)

Traditional indications C!"#

$ia%etes#&c'olesterol#st'a

Vit C ipro*esa%sorption

+rotects s,in *s .V(cancer)# /BC *sradiation


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Cordyceps sinensis Can %e coo,ed it' old dc,

%lac,-%one 'en

lean por, (or en)

ail

%a,ed a%alone (%ronc'itis)

Halpern Cordceps C'inas

'ealin9 s'roo *er# :;1


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冬蟲夏草


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!ordyceps !s$*+ istory and -iscovery 历史和发现

or more than a thousand years, Cordyceps sinensis has beenthe most pri(ed =tonic food> in Asia, especially in !hina. 冬虫夏草千年补品Cordyceps sinensis was recorded in =New Compilation ofMateria Medica> as+ 据新编本草：

sweet and neutral in nature 性甘，中protects lung and kidney function 保护肺及肾功能nourishes the essence and vital energy.

Cordyceps sinensis is primarily a kind of =parasitic mushroom>.

#he principal species !"#$% is Paecilomyces hepiali !hen.%!s$*)/n the late 0123s, /nstitute of Materia Medica, Bei4ing, initiated a03$year program to study Cordyceps sinensis.


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!ordyceps !s$*+ istory and -iscovery历史和发现

/nstitute of Materia Medica successfully developed a deep layerfermentation method for the industrial production of !ordyceps

!s$* in 0156. &'()*+,发-.!hinese Ministry of ealth approved !ordyceps !s$* as the first=!lass$7ne> #!M in 0152. /0123 0 4中&!ordyceps !s$* was commercially introduced in !hina in 0151.5678 0151 %

#here are 8933,333 regular !ordyceps !s$* users in !hinatoday 9:;? %23 mm &MB in 0119 sales).!ordyceps !s$* has one of the most outstanding records ofproduct safety. @A性BC


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Historical历史 - +rotects ln9 and ,idne nction 保护肺D肾功能

- :oris'es t'e essence and *ital ener9 EFGHCurrent现IJKL - +rootes staina# 'ealt' ln9 nction EFGH和肺功能

- ?ncreases endranceEMNH

- @edces ati9e OPQRDose: 5259 capsle 2 capsles tice or t'ree ties dail

it' ood 5259A ST，UV 2-3 WXUW 2 Y

!ordyceps !laims

Z品KL


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!ordyceps and e:ual unction+ ummary

[性功能J\?： • PN0016-2: Placebo-controlled trial

96.;< improvement _`

• PN0074: Double-blind, lacebo-controlled trial99.0< improvement _`

• PN0!41: Placebo-controlled trial

9*< improvement _` = ;;< 02$hydrocortisone= 2.6< 02$ketosterol

• PN0!46: "en trial

perm count Gabc + >>< %from 11 to 0>; million?')Malformed sperms deGa + ;3< %from 23< to 63< %from ;1< to 63


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Agaricus blazei Murillo / -1#4-9lcan-

D#6-9lcan 'as stron9

anti-tor eect inice# &T cells# /BC#

:K cells# C3 acti*it

*s tors

lcan-protein copleE

ond in edi%le

s'roo


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Grifola frondosa %Maitake)Hpo9lceic (dia%etes)

F%lood lipids# $ (not

H$)< 'potensi*erion-$ G *it C *s

prostate cancer cells

Vs o%esit

+rotects li*er *s $-9alactosaine toEicit

&?-6# T:!- prodction


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Phellinus linteus?n s,in creas (*s

a9in9)

"'rin,s elanoa torin ice (G

driacin)< no eect

on etastases

&T-cell# ctotoEic T-cell<

:K-cell# acrop'a9e<

B-cell acti*it


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Trametes versicolor %e: Coriolus

versicolor @un(hi) +"KAKrestin< +"+ter 10# 3 (*s 16)InJ185 o +"K sta9e ?-??

ln9 cancer sr*i*ed

ter 10# 811 (*s 645)InJ227 o +"K (G

c'eo) %reast cancer

sr*i*ed

+"+ (Co*-1)Fside-eects o

c'eo-# radio-t'erap


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!ericium erinaceus %Pompom blanc)Vs ? disorders# %leedin9Hercenon L B# ;--2 att

eEtract a %e c'eo *s

cancer

Helps :!# *s lM'eiers

&T-cell response to Con-#

+"

&ine-ediated s'rin,in9

o tors in ice


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"entinula edodes %hiitake)154 entinan re

+%ed

$e*eloped % Toio

Tada

aNor adN*ant *sali9nancies in Oapan

?pro*es PQ#

tolerance to RT# ddi

in H?VG patients

!i9'ts oral %acteria (*s

caries)


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Agaricus bisporus %!hampignon)+re*ention o %lindness*s +V@

Better 'ealin9 ater

9lacoa sr9er+re*ention o spread o

'an epit'elial

cancer cells< anti-

aroatase (%reast

cancer in post-

enopasal oen)


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De#illed Mushrooms

4509 Agaricus bisporus

60-859 Btter

40l edi +apri,a

40l c'opped an9o c'tne

C'ili# "alt and Blac, +epper# "orCrea

!r t'e s'roos in %tter ntilsot "eason it' c'ili and

pepper "tir in t'e papri,a and

c'tne and a little salt Coo,or a rt'er 4 intes andspoon into a ser*in9 %ol "orrea can %e stirred in# or ser*edseparatel


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Antrodia camphorata

nti-inlaator

+rotects li*er *s toEicit

L i%rosis

nti-*iral (Hepatitis B)

?n'i%its 9rot' o a %reast cancer cell line

:eroprotecti*e


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#ictyophora indusiata %eiled lady)

+rotects or ipro*e C:"# incldin9 ner*e 9rot'

nti-inlaator on %ot' edea L 'peral9esia


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$omitopsis officinalis %Agarikon)

"tptic

Vs *irses elloe*er# "@"# poE

*irses


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茯苓 Poria cocos

Tonic or t'e elderl<

'elps 9rot' inc'ildren

$iretic *s edea

nti-le,eia (Jetoposide)

Vs psoriasis

Topical *s oil s,in L

acne

Vs a%ortion L or9an

reNection

http://www.alternativehealing.org/fu_ling.htmhttp://www.alternativehealing.org/fu_ling.htm


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%ozites caperata %Gipsy)

nti-*iral *s inlenMa # c'ic,en poE# 'erpes

sipleE 1 L 2# respirator snctial *irs

(:ot % eatin9 s'rooS)


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$is% #eal saut&

l% *eal scaloppini

2t% %tter

1c sliced ips s'roos

c sliced scallions incl tops

2t% dr *erot'# or 2t% c'ic,en %rot'

Uc 'ea* crea

1 t% sn-dried toato paste

"at *eal in %tter ntil li9'tl %roned @eo*e ro pandd scallions L s'roos"at li9'tl dd *erot' orc'ic,en %rot' L %rin9 to a %oildd crea L toato pasteCoo, 2 in @etrn *eal to panto 'eat t'ro9'


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Tremella fuciformis %now fungus)

Vs t%erclosis# 'i9' %lood pressre

?no-stilant *s tors

nti-dia%etic


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'teamed Paa%a (roth )ith *lmonds

+ 'no) ungus

1,9 ripe papaa309 sno n9s# soa,ed or 1 'or 609 alonds# soa,ed in 'ot aterand s,inned109 seedless red dates609 roc, s9ar 2 1A2 cps ater

+eel# 'al*e and reo*e seeds ro papaa .sin9 a etal spoon# scoopot t'e les' o t'e papaa Co%inet'e papaa les'# n9s# alonds#

red dates# roc, s9ar and ater in alar9e %ol "tea o*er a slo ire


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#he "nd

#hanks

Documents

HK VTC 25-11-2006 Medicinal Mushrooms