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    Summary

    The HIV/AIDS epidemic

    continues to be a major global

    health challenge, but with U.S.

    support and leadership, an

    AIDS-free generation is within

    reach.

    HIV/AIDS impacts the overall

    development in many of the

    most vulnerable countries

    because it undermines efforts

    to reduce poverty, improve

    access to education and

    healthcare, address gender

    inequalities and maintain

    national security.

    The U.S. is the largest funder of

    HIV/AIDS programs worldwide

    through support for the

    Presidents Emergency Plan for

    AIDS Relief (PEPFAR) and the

    Global Fund to Fight AIDS,

    Tuberculosis and Malaria

    (Global Fund).1

    HIV/AIDS

    Overview

    In 2011, approximately 34 million people worldwide, including 3.4million children under 15, were living with HIV/AIDS. However, the

    number of new HIV infections and deaths from the disease are on the

    decline in many of the hardest-hit countries.2

    In 2011, 1.7 million people died of AIDS-related illnesses and 2.5

    million people were newly infected with HIV.3 In fact, 39 countries have

    seen new infections among adults decrease by more than 25 percent

    between 2001 and 2011, and deaths from AIDS have fallen by one-

    third in the past 6 years.4

    The HIV/AIDS pandemic disproportionately affects sub-Saharan Africa,

    where almost three out of every four new infections occur.5

    Millions of HIV-infected individuals lack the treatment services they

    need to survive and thrive. The number of children accessing

    treatment is especially troubling, with only 28 percent of eligible

    children on treatment compared to 54 percent of eligible adults.6

    The majority of those living with HIV do not know they are infected. 7

    Women represent more than half of all current cases of HIV. Women

    also often have less power in relationships and during sexual

    encounters, leaving them vulnerable to coercion and gender-based

    violence. HIV/AIDS is the leading cause of death among women of

    reproductive age.8

    Stigma, discrimination, legal barriers and the violation of human rights

    pose major obstacles for key populations including men who have

    sex with men, sex workers and people who use drugs to access HIV

    prevention, treatment and care services in many countries around the

    world.

    PEPFAR is the largest commitment by a nation to combat a single

    disease internationally, both programmatically and scientifically.

    Additionally, the U.S. is responsible for 72 percent of global spending

    on HIV/AIDS research and development.9

    The Global Fund was created in 2002 to raise and disburse large sums

    of money around the world to prevent and treat AIDS, tuberculosis andmalaria, diseases that together kill 5 million people every year. An

    innovative public-private partnership, the Global Fund leverages $2 for

    every $1 invested by the U.S. government while maximizing impact by

    working in close coordination with PEPFAR and other U.S. programs.

    James Pursey

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    Making Progress

    As of the end of FY2012, U.S.

    assistance directly supported

    more than 5.1 million patients on

    life-saving antiretroviral

    treatment, and more than 46.5

    million people with counseling and

    testing programs.10

    PEPFAR provided resources and

    funding for the prevention of

    mother-to-child HIV transmission

    for more than 11 million HIV-

    positive pregnant women, allowing

    more than 230,000 infants to be

    born HIV-free in FY2012. Globally over 57 percent of women received the necessary treatment and services

    to reduce transmission from mother to child, up from 15 percent in 2005.11

    As of December 2012, the Global Fund had provided HIV/AIDS treatment to 4.2 million people, as well as

    services to 1.7 million pregnant women. On average, the Global Fund saves 100,000 lives each month with

    its work on HIV, tuberculosis and malaria.

    Recent scientific advances have reinforced the fact that putting HIV-positive individuals on treatment is not only

    good for their own health, but also reduces the likelihood of transmission to others.

    PEPFAR plays a fundamental role in reaching key populations with targeted services and creating an enabling

    environment for working with stigmatized groups in both generalized and concentrated epidemics.

    To ensure that countries are able to sustain and build on progress to date, PEPFAR programs continue to invest in

    building strong health and community systems that increase national capacity to implement country-led HIV/AIDS

    programs.

    PEPFAR has begun to transition from an emergency response to one of long-term sustainability through

    partnerships and country ownership. U.S. investment has been leveraged with other bilateral and multilateral

    partners to create a truly global response.

    U.S. Response and Strategy

    Since President George W. Bushs announcement of PEPFAR in 2003, the U.S. has invested more than $40 billion in

    the global AIDS response. The program was most recently reauthorized through the Tom Lantos and Henry J. Hyde

    United States Global Leadership Against HIV/AIDS, Tuberculosis and Malaria Reauthorization Act of 2008.

    Implemented through the Office of the Global AIDS Coordinator (OGAC) in the Department of State, PEPFAR is a

    multiagency effort supporting HIV/AIDS programs mainly through USAID and the Centers for Disease Control and

    Prevention, with additional programming through the Department of Defense, the Department of Health and HumanServices and the Peace Corps. The program works closely with other major bilateral and multilateral donors such as

    the Global Fund.12

    Scientific advances since the beginning of PEPFAR have improved how we respond to the global HIV/AIDS epidemic,

    and in turn have made U.S.-funded programming more efficient and effective. The PEPFAR program now has a clear

    plan how the U.S. government is going to lead the world towards the end of AIDS in the recent Blueprint Towards an

    AIDS-Free Generation. The Blueprint has a simple goal: make smart investments based on sound science with a

    shared global responsibility in order to achieve an AIDS-free generation.

    Source: AIDSInfo

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    Recommendations

    Congress should maintain strong funding levels for the PEPFAR program. We recognize that these are

    challenging economic times. However, U.S.-funded global HIV/AIDS programs have shown a consistent return on

    investment measured in lives saved, costs avoided through infections prevented and the generation of goodwill

    among global partners. Strong support from Congress, including policies that support the effectiveness of HIV/

    AIDS programming, is critical to advancing the global AIDS response.

    Congress should continue to support the Global Fund. Multilateral funding complements bilateral funding by

    leveraging investments from other donors, helping build country-level commitment and strengthening capacity at

    all levels to deliver programs. U.S. leadership has been and remains the most important leveraging tool available

    to the Global Fund. In the lead up to the Fourth Replenishment of the Global Fund, scheduled for fall 2013, it is

    critically important for the U.S. government to signal to the international community its continued strong support by

    providing robust funding for the Global Fund in FY2014.

    Support scientific advances towards the end of HIV/AIDS. Even with amazing strides toward ending the global

    AIDS crisis, many undiscovered breakthroughs remain. A vaccine and a cure are on the horizon. New

    technologies and treatments could be game changers. Ten years of global HIV/AIDS programming experience will

    pave the way towards an AIDS-free generation if we can harness lessons learned. U.S. support for HIV/AIDSresearch is critical, not just for those suffering from and at risk for HIV/AIDS around the world, but also for the more

    than 1 million people living with HIV in the United States.

    Source: 2012 Country Progress Reports (www.unaidsorg

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    Contributors

    Elizabeth Glaser Pediatric AIDS Foundation

    Katie Lapides Coester

    [email protected]

    International HIV/AIDS Alliance

    Marielle Hart

    [email protected]

    International AIDS Vaccine Initiative (IAVI)

    Jennie Aylward

    [email protected]

    1 Neglected disease R&D: A five-year review, G-FINDER, 2012. Pg. 28.2 Report on the Global AIDS Epidemic, UNAIDS, 2012. Pg. 8.3 Ibid. Pg. 8.4 Ibid. Pg. 11.5

    Ibid. Pg. 11.6 Ibid. Pg. 47.7 Progress Report 2011: Global HIV/AIDS Response, WHO/UNAIDS/UNICEF, 2011.8 Women and Health: Today's Evidence Tomorrow's Agenda, The World Health Organization, 2009.9 Neglected disease R&D: A five-year review, G-FINDER, 2012. Pg. 28.10 World AIDS Day 2012 Update, PEPFAR. http://www.pepfar.gov/funding/results/index.htm.11 On the Road to an AIDS-Free Generation, Dipnote. http://blogs.state.gov/index.php/site/entry/on_the_road_to_aids_free_generation.12 Report on the Global AIDS Epidemic, UNAIDS, 2012. Pg. 11.

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