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Henrietta Lacks’ "immortal" cells
TOP: Henrietta Lacks' (left) cells were essential in developing the polio vaccine and were used in scientific landmarks
such as cloning, gene mapping and in vitro fertilization. (Courtesy of the Lacks family). SECOND: Scanning electron
micrograph of just-divided HeLa cells. Courtesy of National Institutes of Health (NIH)
We know no one lives forever, but one woman's cells from 65 years ago seem to be the
first immortal cells that scientists have. Until not too long ago, it was a mystery where these
cells came from.
Medical researchers use laboratory-grown human cells to learn how cells work and test
theories about the causes and treatment of diseases. They need cells that can grow
indefinitely, be frozen for many years and be divided into different batches and shared
among scientists.
In 1951, a scientist at Johns Hopkins Hospital in Baltimore, Maryland, created the first
immortal human cell line with a tissue sample taken from a young black woman with
cervical cancer. Those cells, called HeLa cells, quickly became very important to medical
By Smithsonian.com, adapted by Newsela staff on 12.21.16
Word Count 795
This article is available at 5 reading levels at https://newsela.com. 1
research. But, no one knew much about the donor. In her book, "The Immortal Life of
Henrietta Lacks," journalist Rebecca Skloot tracked down the story of the source of the
amazing HeLa cells.
Who Was Henrietta Lacks?
Henrietta was a black tobacco farmer from southern Virginia who had cervical cancer
when she was 30. A doctor at Johns Hopkins Hospital took a piece of her tumor without
telling her and sent it to scientists who had been trying to grow tissues. No one knows why,
but her cells never died.
Henrietta’s cells were the first immortal human cells ever grown in culture. Grown in culture
means cells are taken from their environment, like a human body, to a lab so scientists can
grow more of them to study. This is how scientists can learn more about diseases and
sickness. This also helps develop immunizations.
Henrietta's cells were essential to developing the polio vaccine. They went up in the first
space missions to see what would happen to cells in zero gravity. Many scientists have
used her cells for different types of research, including cloning, which is making a copy of
something.
There has been a lot of confusion over the years about the source of HeLa cells. When the
cells were taken, they were given the code name HeLa, for the first two letters in Henrietta
and Lacks. But, Henrietta's real name wasn't known until the 1970s.
Learning Henrietta's Story
Skloot first learned about Henrietta in 1988, years before writing her book. Skloot was 16
and in a science class. The teacher knew Henrietta’s real name and that she was black.
But that’s all he knew and Skloot wanted to know more. Did Henrietta have any kids? What
do they think about part of their mother's cells being alive all these years after she died?
Years later, when Skloot was in college, she decided to find Henrietta's family and write
about them.
Skloot was determined to tell Henrietta's story. It took almost a year even to convince
Henrietta’s daughter, Deborah, to talk to Skloot. Skloot went to Clover, Virginia, where
Henrietta was raised. Skloot tracked down Henrietta's cousins, then called Deborah and
told her their stories. This convinced Deborah to help Skloot learn more about Henrietta
because Deborah wanted to know more, too.
Deborah never knew her mother; she was an infant when Henrietta died. No one ever
talked about Henrietta. So when Deborah found out that this part of her mother was still
alive she became desperate to understand what that meant.
This article is available at 5 reading levels at https://newsela.com. 2
Finding Out HeLa Is Henrietta Lacks
Twenty-five years after Henrietta died, a scientist discovered that many cell cultures
thought to be from other tissue types, including breast and prostate cells, were in fact
HeLa cells. It turned out that HeLa cells could float on dust particles in the air and travel on
unwashed hands into other cell cultures.
So, scientists tracked down Henrietta’s relatives to take some samples from them to use
the family’s DNA to make a map of Henrietta’s genes. This would allow scientists to know
which cell cultures were HeLa and which weren’t. It would begin to straighten out the
contamination problem.
Lessons From The Book
For scientists, one of the lessons is that there are human beings behind every biological
sample used in the laboratory. Much of science today revolves around using human
biological tissue of some kind. The people behind those samples often have their own
thoughts and feelings about what should happen to their tissues, but they’re usually left out
of the equation.
Skloot hopes people don't think tissue culture is bad because medicine today depends on
tissue culture. The need for these cells is going to get greater, not less, Skloot said. She
added that scientists just need to look at how this can happen in a way that everyone is
OK with.
Many tests, basic drugs and all of our vaccines would not exist if it wasn’t for scientists
collecting cells and growing them. Or, if it wasn't for Henrietta.
This article is available at 5 reading levels at https://newsela.com. 3
Quiz
1 Which answer choice BEST explains the cause of the confusion about where HeLa cells came
from?
(A) We know no one lives forever, but one woman's cells from 65 years ago
seem to be the first immortal cells that scientists have. Until not too long ago,
it was a mystery where these cells came from.
(B) In 1951, a scientist at Johns Hopkins Hospital in Baltimore, Maryland,
created the first immortal human cell line with a tissue sample taken from a
young black woman with cervical cancer.
(C) When the cells were taken, they were given the code name HeLa, for the first
two letters in Henrietta and Lacks. But, Henrietta's real name wasn't known
until the 1970s.
(D) The people behind those samples often have their own thoughts and
feelings about what should happen to their tissues, but they’re usually left
out of the equation.
2 Which section of the article BEST explains that Henrietta Lacks' cells were taken without her
permission?
(A) the introduction [paragraphs 1-3]
(B) "Who Was Henrietta Lacks?"
(C) "Learning Henrietta's Story"
(D) "Finding Out HeLa Is Henrietta Lacks"
3 How does the article convey the importance of Henrietta Lacks' cells?
(A) by quoting excerpts from a book about the life and impact of Henrietta
Lacks
(B) by describing events from the childhood of Henrietta Lacks' daughter
(C) by detailing the scientific process of collecting and growing HeLa cells
(D) by giving examples of the scientific advances made using HeLa cells
This article is available at 5 reading levels at https://newsela.com. 4
4 Which answer choice BEST explains Rebecca Skloot's purpose in writing her book?
(A) to share information about the life and family of the woman behind the
famous HeLa cells
(B) to bring fame and fortune to the other members of the Lacks family
(C) to show the importance of properly labeling cells in a laboratory
(D) to give evidence to suggest that scientists should take human cells without
permission
This article is available at 5 reading levels at https://newsela.com. 5