Health Economics and Health Technology AssessmentAnnual Report 2016

2

Contents

From the Director 4

Meet the Team 6

Visitingresearchersandaffiliates 9

PhD students 11

Strategic activities 12

Internationalisation 13

Worldclassenvironment 15

Innovative engagement 16

Highlightsof2016 18

Research 20

Research themes 21

Projectsawardedin2016 22

Ongoingprojects 23

Projectscompletedin2016 26

NIHR CRSU 27

Aresearcher’sperspective–CaoimheRyan 28

TeachingandSupervision 30

ContinuingProfessionalDevelopment 32

Publications 34

Presentations 37

MembershipofExpertBodies 40

3

From the Director

4

Welcometoourfifthannualreport,which provides an overview of themanyaccomplishmentsthat

wecelebrateattheHealthEconomicsandHealthTechnologyAssessment(HEHTA)ResearchGroupin2016.Thispastyear,myfirstinmynewroleasDirector,hasbeenanotherhighlysuccessfulandproductiveyearfortheteam.Amongourresearchandteachinghighlights,isourgrowinginternationalcollaborationsandpublicengagementinitiatives.Ihopeyouwillenjoyreading about our new projects funded by theEuropeanCommissiononevaluationsofcomplexclinicalandpopulationhealthinterventions,andourpublicengagementexerciseonprioritisinghealthcarefundingallocations.

OneofthecelebrationsIwouldliketohighlight,isthepromotionofourDeputyDirector,DrEmmaMcIntoshtofullProfessorofHealthEconomics.DrMcIntoshjoinedHEHTAin2011,andhasbeendedicatedtoshaping HEHTA into a team that produces high-qualityworkwithinasupportingandnurturingenvironment.Overtheyears,shehasundertakenhighlyimpactfulresearchandsuccessfullyraisedHEHTA’sprofileinHealthEconomicsofPublicandPopulationHealth.Thisisamajorpersonalachievement,andawell-deservedrecognition of her contribution to HEHTA and theUniversity.

In2016,wealsomarktheintroductionof an exciting new research theme – ‘EconomicsofPrecisionMedicine’.Thisresearchthemecomplementsoneofthe

achievementsofourCollegeofMedical,Veterinary & Life Sciences in becoming akeyplayerinaScottish“globalcentreofexcellence”inprecisionmedicine.WearedelightedtowelcomeProfessorNeilHawkins,whojoinedusasProfessorofHealthTechnologyAssessment,toleadthisresearchtheme.ProfessorHawkins’sresearchfocusesonmethodologicaldevelopmentofevidencesynthesisanddecisionanalyticalmodelling,andintheirapplicationtoprecisionmedicineandearlystagehealthtechnologyassessment.Welookforwardtoreportingactivitiesfromthisresearchthemenextyear.

5

DIRECTOR

OliviaWu ProfessorofHealthTechnologyAssessment

DEPUTY DIRECTOR

Emma McIntosh ProfessorofHealthEconomics

PROFESSORS

Andrew Briggs WilliamR.LindsayChairinHealthEconomics

NeilHawkins ProfessorofHealthTechnologyAssessment

READER

Jim Lewsey

LECTURERS

KathleenBoydHannahHesselgreavesClaudiaGeue

RESEARCHERS

CamillaBabaWillingsBothaJanetBouttellNickiBoyerManuelaDeiddaEleanorGrieveRobert HeggieNicolaMcMeekinMinnie ParmiterZahidulQuayyumMohsen RezaeihemamiJoseAntonioRoblesZuritaCaoimhe RyanMiranda TrevorYiqiao Xin

PHD STUDENTS

YuliaAnopaGiorgio Ciminata Tadesse Gebrye CiaranKohli-LynchPattaraLeelahaverongClaireWilliams

VISITING RESEARCHERS

Shawn HsiehBrunoSalgadosRiveros CarlosWong

Meet the Team

6

AFFILIATES

Houra HaghpanahanPeterMcMeekin

HONORARY STAFF

HenryGlickKaren RitchieJames Robinson

ADMINISTRATORS

MoiraAitkenCarolineCecilJennieClarkAliedaMcKinney

7

In2016wewelcomedtotheteam...

ManuelajoinedHEHTAasaResearchAssociate,workingontwoprojects.Thefirstoneisabouttheeconomicevaluationofacomplexinterventiononsedentarybehaviourandphysicalactivityalongsideamultinationalrandomisedcontrolledtrial(RCT).Thesecondoneconcernseconomicevaluationofa means-tested voucher directed towards pregnant womenandmothersofchildrenunderfour.PriortojoiningHEHTAManuelaheldpositionsinacademia(UniversityofCagliariandUniversityofBolzano)andininternationalinstitutions(EuropeanCentralBankandEuropeanCommissionJointResearchCentre).Shehasworkedinarangeofareas,includinghealthtechnologyassessment,publicpolicyevaluation,households’economics,andtelemedicineandtelehealthsystems.

NeilisournewProfessorofHealthTechnologyAssessment(HTA)atHEHTA.HehasextensiveexpertiseinHTA,withparticularfocusonevaluationofearlystagetechnologies,precisionmedicine,evidencesynthesisanddecisionanalyticalmodelling.NeilwillleadanewresearchthemeinHEHTA,‘EconomicsofPrecisionMedicine’,developedtocomplementtheCollegeofMedical,VeterinaryandLifeSciences(MVLS)leadingpositioninprecisionmedicine.PreviouslyhewasaReaderattheLondonSchoolofHygieneandTropicalMedicine,andVicePresidentleadingtheglobalHealthEconomicspracticeatICONplc.HeisaregularadvisortopharmaceuticalandbiotechindustriesaswellastheNationalInstituteofHealthandCareExcellence(NICE)ScientificAdviceProgramme.

Joseisworkingoneconomicevaluationalongsideclinicaltrialsinvolvingtreatmentsandinterventionsindifferentcardiovasculardiseases,mentalhealthandcancer.HeholdsaMaster’sdegreeinEconomicsandWelfareEvaluationandPhDinEconomicsfromPablodeOlavideUniversity(Spain).José’sPhDthesisfocussedontheapplicationofpsychologytotheanalysisofeconomicdecisionsinthedomainofhealth.AsaPhDstudenthewasalsoavisitingresearcheratYunusCentreforSocialBusinessandHealthatGlasgowCaledonianUniversityandintheDepartmentofEconomicsattheUniversityofAlicante.Josehasworkedinacademiaandinotherpublicorganizations for over eight years combining research andteaching.

Caoimhe joined HEHTA as a qualitativeResearchAssociate,workingprimarilyonthequalitativepost-trialcomponentoftheCancerandVenousAccess(CAVA)trial.CaoimhecompletedaPhDinSocialPsychologyattheUniversityofStAndrews,whichinvestigatedsocialidentityandrepresentationingrassrootsanti-deportationcampaigns.Priortoherdoctoraltraining,sheworkedontwoconsecutiveChiefScientistOffice(CSO)projectsattheUniversityofStirlingandtheUniversityofStrathclydeinvestigatingpsychologicalfactorsassociatedwithsuicidalbehaviourandrepeatedself-harm.CaoimhealsohasanMScinSocialandCulturalPsychologyfromtheLondonSchoolofEconomics.

Manuela Deidda

Jose Antonio Robles-Zurita

Caoimhe Ryan

Neil Hawkins

8

VisitingResearchersandAffiliates

WewelcomedDrCarlosWong,Research Assistant Professor of theDepartmentofFamilyMedicineand Primary Care at the University ofHongKong.Carlos’sresearchinterestsarepatient-reportedoutcomemeasurementincludingqualityoflifeandhealthservicesresearch,particularlyretrospectiveadministrative database research and cost-effectiveness analysisofhealthcareinterventions.Carlosspenttwomonthswithus,andworkedontworesearchprojects,oneevaluatingthecost-effectivenessanalysisofrenalreplacementtherapyamongend-stagerenaldiseasepatientsinHongKong,andasecondexploringincrementalcosteffectivenessratio(ICER)thresholdsindecisionstoacceptemerginghealthtechnologyinHongKong.

HourajoinedHEHTAinMay2016asapart-timeresearcher,toworkasan econometrician on a CSO funded study to investigate the impact of tobaccocontrolMassMediaCampaignsonquittingbehaviour,smokingprevalenceandsmoking-relatedhealthoutcomesapplyingtimeseriesanalysis.Hourareceived a BSc degree and an MSc degree in Economics from Shahid Beheshti University in Iran before completingherPhDinEconomicsattheUniversityofLeicesterinJuly2015.HermainresearchinterestsareinHealthEconomicsandAppliedEconometrics.ShejoinsHEHTAfull-timeinJanuary2017.

Bruno Riveros is a visiting postgraduate research student from Brazil.HeisworkingonhisPhDwhichfocusesontheefficiencyofdifferentstrategiestotreatobesity/overweight.Todothis,heisadoptingaScottishCardiovascularDiseasesPolicyModeltotheBraziliansetting.Inparallel,heisdevelopingaconceptualmodelforotherHEHTAprojectscurrentlyinprogress.

PingHsuan(Shawn)Hsiehjoinedus as a visiting researcher for six months.ShawnhasanMScinTransdisciplinaryLongTermCareandaBScinPharmacy.DuringhistimewithHEHTA,heworkedonaresearchprojectonscreeningforhepatitisBandCinfections.HealsoengagedinlearningmethodologicalapproachestoHTA.

Peter joined HEHTA as a visiting Fellow.Afterstudyingeconomicsasanundergraduate,heobtainedanMScinHealthEconomicsfromYorkUniversity,beforeaPhDinHealthEconomicsfromNewcastleUniversity.Hehasbeenaco-applicantonseverallargeNIHRgrants.Hisresearchinterestsincludeemergencymedicine,transformationandchangeintheNHS,anddecisionmodelling.PeterisaFellowoftheHigherEducationAuthority.

Carlos Wong

Bruno Salgados Riveros

Ping Hsuan (Shawn) Hsieh

Houra Haghpanahan

PeterMcMeekin

9

…and we said goodbye to

Minnie Parmiter was with HEHTA for just over a year and workedwithEleanorGrieveoneconomicevaluationswithintheGlobalHTAtheme.

MirandaTrevorjoinedHEHTAin2014asatraineeresearcher,andhaslefttocommencehermedicalstudiesattheUniversityofNewcastle.

ZahidQuayyumwaswithHEHTAfortwoyears,workingonanumberofprojectsincludingCULPRIT-SHOCK.ZahidiscurrentlyattheBlizardInstitute,QueenMary,UniversityofLondon.

Minnie Parmiter Zahidul Quayyum

Miranda Trevor

10

PhD StudentsSubmitted in 2016

Camilla Baba ‘Valuing the health and wellbeing aspects of community empowerment using economic evaluation techniques’Supervisors: Emma McIntosh, Carol Tannahill (external)

Willings Botha‘Economics of forestry based health interventions’Supervisors: Andrew Briggs, Richard Mitchell (external)

Current students

Yulia Anopa‘Economics of paediatric caries prevention’Supervisors: Emma McIntosh, Lorna Macpherson (external)

Janet Bouttell‘Methods of early health technology assessment in precision medicine’Supervisors: Andrew Briggs, Neil Hawkins

Nicki Boyer‘Economic Evaluation of population health interventions’Supervisors: Emma McIntosh, Kathleen Boyd

Giorgio Ciminata‘Cost-effectiveness of new anticoagulant drugs using real world data within the Scottish population’Supervisors: Olivia Wu, Claudia Geue, Peter Langhorne (external)

Shadrach Dare‘A retrospective cohort study of the risk factors for neonatal sepsis and other pregnancy related adverse outcomes in Ghana’Supervisors: Danny Mackay (external), Jill Pell (external), Hannah Hesselgreaves

Karl Ferguson‘Diagram based analysis of causal systems for understanding the causes of alcohol problems’Supervisors: Jim Lewsey, Mark McCann (external), Danny Smith (external)

Ben Fulton‘Quantitative research of patient preferences and perceptions of precision medicine in Oncology’Supervisors: Robert Jones (external), Emma McIntosh, James Paul (external)

Tadesse Gebrye‘Cost-effectiveness analysis and modelling the lifetime costs and benefits of health behaviour interventions on Diabetes (Type 2)’Supervisors: Emma McIntosh, Kathleen Boyd

Eleanor Grieve‘A Methodological Approach for Evaluating the Impact of Health Technology Assessment’Supervisors: Andrew Briggs, Olivia Wu, Hannah Hesselgreaves

Ciaran Kohli-Lynch‘Primary prevention of cardiovascular disease in disadvantaged populations: a comparison of modelling methods in the UK and the US’Supervisors: Andrew Briggs, Kathleen Boyd

Pattara Leelahavarong‘Development and validation of alcohol use disorder prediction model for monitoring and evaluation of alcohol consumption control programmes in Thailand’Supervisors: Andrew Briggs, Jim Lewsey

Ana Cristina Perez‘Fatigue and dyspnoea in heart failure: insights from two large randomised clinical trials’Supervisors: John McMurray (external), Jim Lewsey

Yiqiao Xin‘Impact of variation of economic evaluation methods on the cost-effectiveness result: a case study of deep brain stimulation (DBS) in Parkinson’s’Supervisors: Emma McIntosh, Jim Lewsey

Claire Williams‘Demonstrating the potential of multi-state survival models for enhancing epidemiological and health economic modelling’Supervisors: Jim Lewsey, Andrew Briggs, Danny Mackay (external)

11

ReflectingtheUniversityofGlasgowstrategy:tobringinspiringpeopletogetherandcreateaworld-classenvironmentforlearningandresearch,empoweringstaffandstudentsaliketodiscoverandshareknowledgethatcanchangetheworld.

Strategic Activities

12

Bringinspiringpeopletogether-connectwiththeworldthroughinternationalisation

HEHTAinvestigatorsarecollaboratingonseveralinternationalprojects.HerewehighlightthreeEuropeanCommissionprojects.

SITless: Exercise Referral Schemes enhanced by Self-Management Strategies to battle sedentary behaviourFunder: European Union, Horizon 2020 Research and Innovation Programme

TheSITlessstudyisamulti-national,multi-centre,three-armrandomisedclinicaltrialaimingtoinvestigatethelong-termeffectsofacomplexinterventiononsedentarybehaviourandphysicalactivityinacommunity-dwellingolderpopulation.Theinterventionisbasedonexistingexercisereferralschemes(ERS)enhancedbyasocialcognitivegroupinterventiononself-managementstrategies(SMS).Thelong-termcost-effectivenessofajointinterventionofERSandSMSisevaluatedagainsttwoalternatives-ERSaloneandusualcare.

The costs of providing ERS enhanced by SMS are identifiedfromnationalhealthserviceandpersonalsocialservicesperspectivesalongsidepotentialcostimpactsincludinghospitalisations,accidentandemergencyvisits,andappointmentswithhealthprofessionals.Outcomesincludeself-reportedhealthrelatedQualityAdjustedLifeYears(QALYs)whichareobtainedusingtheEQ-5DEuroQolinstrument(EQ-5D)aswellasthenewlydevelopedcapabilitiesmeasureofoutcomesforolderpeople,theICECAP-Oinstrument.Country-specifictariffsarealsoused.Thewithin-trialeconomicevaluationresultsarecombinedwithevidencefromtheliteraturelinkingshort-termandlongertermoutcomes to produce a cost-effectiveness decision analyticmodel,usingaMarkovmodel.Adetailedsensitivityanalysisexploreshowcost-effectivenessvarieswithinalltherealisticrangesofcostsandoutcomes.

Thestudyalsoconsiderstheadditionalchallengesrelatedtotheevaluationofcomplexpublichealthinterventionsofthistypeaswellastothemulti-countrynatureoftheintervention.HEHTA Principal Investigator: Professor Emma McIntosh

PATHway: Technology enabled behavioural change as a pathway towards better self-management of CVDFunder: European Union, Horizon 2020 Research and Innovation Programme

The PATHway Consortium comprises eight partners from acrossEurope.PATHwayproposesanovelapproachtoCardiacRehabilitation(CR)aimedatempoweringpatientstomoreeffectivelyself-managetheirCardiovascularDisease(CVD).Thehealtheconomicanalysiscombinesandevaluateshealthoutcomesand resource use consequences of the PATHway interventiontodetermineincrementalcost-effectivenessofPATHwaycomparedwithusualcare.Thewithin-trialanalysisfocusesonthetrialperiodofsixmonthsandanextrapolationoftrialresultswillallowustodeterminelifetimecostsandoutcomesandlong-termcost-effectivenessbeyondthetrialperiod.

Resourceutilizationincludesthecostofdeliveringtheprogramme(eitherPATHwayorusualcare,asinterventioncost),thehealthservicecosts(healthcarecosts),thecostsfallingontheparticipants(directnon-medicalcosts)andtheproductivityeffectsintermsofpatients’employment(lostproductivity).Health-relatedoutcomemeasuresincludephysicalactivityandqualityoflife(EQ-5DEuroQolinstrument).Alownumberofclinicaleventsisanticipatedtobeobservedduringthetrialperiodsothatparameterestimateswillneedtobeobtainedfromtheepidemiologicalliteraturethatlinkschangesinexercisecapacitywiththeprobabilityofexperiencingadverseclinicalevents.

13

LinkingchangesinexercisecapacityandriskprofilestorecurrentCVDeventsandCVDmortalitywewillestimatethecostperQALYassociatedwithPATHwayandidentifywhetherthecostsrelatedtoPATHwayareoffsetbyareductioninclinicaleventsandrelatedhospitalisationsinthelongterm.

TheEuropeanCommissionreviewinMarch2016reportedveryfavourableprogressinyearone.TheCommissionreportedthattheconsortiumisclearlyadvancingstate-of-the-artandprovidinganexampleforuser-centreddesignthatcanbeamodelforotherEUprojects.HEHTA Principal Investigator: Professor Andrew Briggs

CULPRIT-SHOCK: Multivessel versus culprit lesion only percutaneous revascularization in patients with acute myocardial infarction complicated by cardiogenic shock Funder: European Union, 7th Framework Programme

The CULPRIT-SHOCK Consortium consists of 17 partnersfrom11differentEUmemberstatesaswellasSwitzerland.Cardiogenicshockcomplicatingacutemyocardialinfarction(AMI)representsamajorEuropeanhealthcareconcernwithmortalityratesbetween40%and70%.Theclinicianisfacedwiththedecisiontoeitherinterveneonlyontheculpritlesionacutelyresponsiblefortheinitiationofcardiogenicshock,ortotreatadditionallesionsconsideredhemodynamicallysignificantbutnotacutelytriggeringtheshockcascadeaswell.TheaimoftherandomizedCULPRIT-SHOCKtrialistocompareimmediatemultivesselPercutaneousCoronaryIntervention(PCI)versusculpritlesiononlyPCIinpatientswithAMIcomplicatedbycardiogenicshock.

Theeconomicevaluationwillcomparethetwointerventionsanalysed:1)culpritvesselonlyPCIwithpotentiallysubsequentstagedrevascularization,and;2)immediatemulti-vesselrevascularizationbyPCI.Theeconomicevaluationcomprisesbothcost-effectivenessanalysis(CEA)andcost-utilityanalysis(CUA).TheCEAwillusetheoutcomemeasuresof30-daymortalityandrenalfailure.QALYswillbeusedfortheCUA.Thewithin-trialanalysiswillprovideestimatesofcostperlifesavedat30-dayandinoneyear,andestimatesofhealth-relatedqualityoflife.Thelong-termanalysiswillcombinewithin-trialinformationandevidencefromtheliteraturetopopulatethepre-trialmodelthatwillallowustocomputeincrementalQALYs.Themodelling-basedanalysiswillprovideexpectedcostsandhealthoutcomes,andincrementalcost-effectivenessratiooverthelifetimeforthecohortofpatientsincludedinthetrial.Theeconomicevaluationwillincludehealthsystemsandsocietalperspectives,suchasinterventioncosts,medication,andproductivityloss.Thecost-effectivenessanalysiswillbefromtheperspectiveofeachcountry’snationalhealthservices.

Uponcompletion,CULPRIT-SHOCKwillbethelargestrandomizedcontrolledclinicaltrialinpatientswithcardiogenicshockeverconductedandwillinformpatients,healthcareproviders,anddecision-makersaboutwhichpercutaneousrevascularizationstrategyismosteffective.HEHTA Principal Investigator: Professor Andrew Briggs

14

Create a world-class environment for learningandresearchAcrosstheworld,governmentsareincreasinglyestablishingHTAprogrammesandagencies.Thereforethere is an increasing need to train HTA practitioners to informthedecisionmakingprocess.Inresponsetothis,HEHTAdevelopedapostgraduateprogrammeandourMScinHTAranforthefirsttimein2013.

Twoyearsagowedevelopedourprogrammetobedeliveredasonlinedistancelearning(ODL)toincreaseourglobalreachandtoofferflexibilitytothosewhowanttoremainintheiremploymentbutwouldliketoup-skillatthesametime.OurpostgraduatetaughtcoursesprovideasolidgroundinginallthemajordisciplineswithinthefieldofHTA.ThisisuniquewithinScotland,andisoneoffewsuchprogrammesworldwide.Ourteamareworld-classexpertsintheirfields,andareactivenotonlyinresearchandteaching,butalsoinHTAdecision-makingatanationallevel(e.g.throughNICEandScottishHealthTechnologiesGroupatHealthcareImprovementScotland).

Ourteachingisresearch-led.Thecourseshavebeendevelopedtoreflectthelatestacademicresearchandup-to-datechallengesinHTAdecision-making.Students gain a comprehensive understanding and hands-onexperienceoftheinterconnecteddisciplinesthatarecoretoHTA.Theseincludehealtheconomics,statistics,evidencesynthesis,modellingandpatient-reportedoutcomemeasures.Inacademicyear2016-17wehave17students.

MSc HTA:requiresatotalof180creditstobecompletedoverthecourseofthedegree.60creditsfrom3corecourses,60creditsfromoptionalcourses,60creditfromaresearchproject.

PgDip HTA:requiresatotalof120creditstobecompletedoverthecourseofthedegree.60creditsfrom3corecourses,60creditsfromoptionalcourses.

PgCert HTA:requiresatotalof60creditstobecompletedoverthecourseofthedegree.60creditsfrom3corecourses.

Core courses (20 credits each) • HTA:policyandprinciples • StatisticalMethodsforHTAandevidencebased medicine • HealthEconomicsforHTA

Optional courses (credits) • Decisionanalyticmodellingmethodsfor economicevaluation*(20) • OutcomemeasurementandvaluationforHTA(10) • QualitativeresearchmethodsinHTA(10) • HTAinaglobalcontext(20) • SurvivalanalysisforHTA(10) • Foundationsofdecisionanalyticmodellingfor HTA(10) • Evidencesynthesis(20) • Analysisoflinkedhealthdata(20)

*Thiscourseisonlyavailableasaface-to-facecourseinGlasgow.

‘Great online course, that makes you feel like you are actually in a classroom rather than on your own.’

‘I was sceptical about online learning at first, but it has exceeded my expectations by encouraging participation and providing a vast and useful range of course materials, including recorded lectures.’

‘This course provided a good introduction to survival analysis for HTA, allowing for both a theoretical and practical understanding of the topic.’

‘I’ve found the learning experience to be convenient and flexible. It suits me to participate at a time, and for a duration, that fits my professional and personal schedule too.’

‘I appreciate having so many resources at hand, being able to replay lectures as and when needed to aid understanding and retention.’

‘...a lecture room that goes wherever you want.’

15

Discoverandshareknowledgethatcanchangetheworld-throughinnovative engagementHEHTAhasbeenpromotingitsheadlinemakingresearchandengaginginpublicdiscussionsandactivitiesdemonstratingtheimpactofhealtheconomicresearchondailylivesandhealth.

ExplorathonHEHTAwasselectedtohostaresearchstationatGlasgowScienceCentre.TheeventwaspartofEuropeanResearchers’Night,heldsimultaneouslyacrossEuropeonthelastFridayinSeptemberfundedbytheEuropeanCommissionundertheMarieSklodowska-Curieactionsprogramme.

TheHEHTAstationentitled‘TheHealthMinister’sDilemma’,invitedthepublictobecomedecisionmakersinatrade-offtaskinvolvingabudgetandoptionsforfunding.Researchersalsodemonstratedexamplesofhealthmeasurementtoolsanddiscoveredhowthepublicdefinequalityoflifeandhealth,throughcontributionstoadisplayofvalueofhealthdefinitions.

The Health Minister’s Dilemma stand

Festival of Social SciencesPromotingourportfolioofworkonalcoholinterventionsandoutcomes,theHEHTAteamandcollaboratorsfromNHSScotland(MarkRobinsonandMatthisHeydtmann)hostedastandatGlasgow’sfamousBarrasMarketaspartoftheEconomicandSocialResearchCouncil(ESRC)nationwidefundedFestivalofSocialSciences.Membersofthepublicwereinvitedtospendahypotheticalpotofmoneyonthreeoutoffourinterventionstoreducealcoholconsumptionorchangedrinkingbehaviour.

Thepublicwereaskedtochoosebetweenfundingthefollowinginterventions;minimumunitpricingforalcohol,counsellingtochangedrinkinghabits,bedsinintensivecareforpatientswithliverfailureorsettingthealcohollimitfordrivers.Afterlotsofdeliberationanddiscussion,thefinalresultsindicatethatthepublicvotecomesdownheavilyinfavouroffundingcounsellingtochangedrinkinghabits.

Alcohol interventions- the public decides

Public Health Research Workshop – exploring physical activity for health and funEmmaMcIntoshandManuelaDeiddaparticipatedinthePublicHealthResearchWorkshop,‘Exploringphysicalactivityforhealthandfun’,attheNationalFootballStadiumofScotlandHampdenPark,UK.Theevent,runbytheEUDirectorate-GeneralResearchandInnovation,invitedfiveongoingEuropeanUnionFP7andHorizon2020researchprojectsonhealthenhancingphysicalactivitytosharetheirexperienceswithotherstakeholders,todiscusshowtoenhancephysicalactivity,sharebestpracticesandtodrawsomeconclusionsandrecommendationsforpolicymakers.

16

Defining what affects Quality of Life

17

Highlights of 2016SPRING

WelaunchedourfirstonlineCPDcourse,HealthEconomicsforHTAinApril.SixteenpeopleattendedfromSpain,Indonesia,andtheUK.

AttheBMJAwards,KathleenBoydandEmmaMcIntosh’spaper‘BronchiolitisofInfancyDischargeStudy(BIDS):amulticentre,parallel-group,double-blind,randomisedcontrolled,equivalencetrialwitheconomicevaluation’wasawardedUKClinicalResearchPaperoftheYear.

WewelcomedNeilHawkinsasournewProfessorofHTA.NeilwillleadonournewthemeofEconomicsofPrecisionMedicine.

Some HEHTA team members completetheEdinburgh marathon.

SUMMER

Morecelebrationsas Emma McIntosh was promoted to Professor of HealthEconomics.

JimLewseyandJennieClarkattendedtheSocietyforMedicalDecisionMaking(SMDM)16thBiennialEuropeanConferenceinLondontopresentworkonanaturalexperimentevaluatingtheAlcoholAct.

Robert Heggie (left),completedtheMontBlancmarathon.

Emma McIntosh completedtheIsleofSkyehalfmarathon – what a sporty team!

TheNIHRComplexReviewsSupportUnit(CRSU)turnedoneyearold.TheNIHRCRSUprovidestimelyandappropriatesupportforthedeliveryofcomplexreviewsthatarefundedand/orsupportedbyNIHR.

AbigcongratulationstoCamillaBabawhosuccessfullydefendedherPhDthesisatherviva.

AUTUMN

WewelcomedvisitingresearcherDrCarlosWong,Research Assistant Professor of the Department of FamilyMedicineandPrimaryCareattheUniversityofHongKong.

HEHTAparticipatedintheExplorathoneventatGlasgowScienceCentre(seepage16formoreinformation).

Wewelcomedover80participants to our Decision AnalyticModellingCourse,whichincludedadinneratthestunningOranMor.

18

BuildinglinkswithSouthAmerica,HEHTAwelcomedvisitorsfromBraziltodiscussdifferencesinHTAbetweenthetwocountries.TheBrazilianPublicHealthSystemhas been undergoing major change in thelastfewyearssince the creation oftheNationalCommittee forHealthTechnologyIncorporation (CONITEC).

AspartofourregularGlasgowhealthEconomicsSeminarSeries(GhESS),ProfessorJohnCairnsfromLSHTM presented us with an interesting seminar on ‘A novelmethodforcollectinghealthstateinformationfromchildren’,describingthedevelopmentofanewtoolforcollectingdataonself-reportedhealthfromchildren.

ProfessorPhilipClarke,headfortheHealthEconomicsUnitattheCentreforHealthPolicyatUniversityofMelbourne,Australia,presentedanexcellentGhESS seminaron‘EconomicEvaluation:ABriefHistory’.Itprovidedabroadoverviewofthedevelopmentofeconomicmethodsforevaluatingpublichealthandmedicalinterventionspriortothe1970s.

The team had great fun at the HEHTA Away Day 2016tryingtoescape from The RiddleRoomsandEscape Rooms!

Jim Lewsey reprepresented HEHTA at ISPOR 7th Asia PacificConferenceinSingapore.Aswellaspresentingapaperon‘Developmentofanalcoholpolicymodelthatpredictslifeyears,QALYsandhealthcarecostsaccountingforalcoholusedisorderidentificationtest’,JimwelcomedmanyvisitorstoourstandwhowereinterestedinourMSconlineCPDcourses.

ProfessorJamesRobinsonfromBerkeleyCentreforHealthTechnology,UniversityofCaliforniaprovokedsome great discussion during his seminar about differencesbetweenUSandUKhealthsystems.

WINTER

ProfessorNickHanleyfromtheDepartmentofGeographyandSustainableDevelopment,UniversityofStAndrewsgaveafascinatinglunchtimeseminaratHEHTAonchoicemodelling.

HEHTA participated in theFestivalofSocialSciencesatGlasgow’sBarras.

HEHTA team membersclimbedThe Whangie with CarlosWongasafinalgoodbye.

JanetBouttellwas awarded the firstdistinctionon our MSc HTA programme.

CiaranKohli-LynchwasawardedtheLeeBLustedstudent prize for outstanding presentation of research atSMDMforhisposteron‘SignallingDemand:PCSK9InhibitorsforStatinIntolerantIndividuals’.

HEHTA staff were wellrepresentedat the Institute ofHealthandWellbeing’sChristmas dinner andceilidh!

19

Research

Markov modelling being born

20

HEHTA’sworkiscentredaroundeightcoreandinterconnectedresearchthemes.

Analysis of Linked Health Data (ALDA)ThisprogrammeencompassesallresearchworkinHEHTAthatisassociatedwithstatistical,epidemiologicalandeconomicanalysisoflinkedhealthdatasets.Ourteamhasawealthofexpertiseandexperienceinthisfield–forexampledatamanipulationandidentifyingcohortswithinlinkeddatasets;regressionmodellingofpaneldatasets;outcomemeasurement,costinganddevelopingdecisionanalyticmodelsusinglinkeddatasets.

Decision Analytic Modelling and Simulation for Evaluation in Health (DAMSEL)This programme encompasses research associated with conductinganevaluationusingmodellingorsimulationmethods.Modellingcanbeusedasthewholeframeworkforanevaluation,oraspartofaclinicaltrial-basedevaluationtoextrapolateintermediatetrialendpointstofinalhealtheconomicoutcomes.DAMSELcutsacrossandinteractswithmanyoftheotherthemesofHEHTA.

Economics of Population Health (EPH)Thisprogrammeisconcernedwiththedevelopmentofmethodsandrelatedempiricalworkassociatedwiththeeconomicevaluationofpopulationhealthinterventions,includingthosethatmaybedeliveredoutsideconventionalhealthservices.Thethemeisparticularlyinterestedintheevaluationof‘up-stream’influences,suchasearlylifeexperiences,thesocialandeconomicconditionsinwhichpeopleliveandenvironmentalexposuresaffectwellbeing.

Incorporating Perspectives and Experiences (IPE) ThisprogrammeaimstopromoteanddeveloptheapplicationofqualitativemethodologiestoHTA.QualitativeresearchisusefulforinvestigatingstakeholderbehavioursandcontextualaspectsofevaluationsandHTA.Researchinthisprogrammefocusesonthedevelopmentandapplicationofqualitativemethodologiestoconceptualmodelling,trialrecruitmentanddesign,developingmeasures,evidencesynthesis,andprocessevaluation.ThethemeoffersatoolkittosupportworkacrossHEHTA’sotherthemes.

Evidence Synthesis (ES) Thisprogrammeencompassesallresearchworkassociatedwithcombiningmultiplesourcesofevidenceforclinicalandeconomicevaluations.AlongsidetheNIHRComplexReviewsSupportUnit(CRSU),thisprogrammewillexplorechallengesincombiningcomplexdatatypesandstructure,throughmethodologicalandappliedresearch.

Economic Evaluation alongside Clinical Trials (EEACT)Thisprogrammeencompassesallresearchworkassociatedwithconductinganeconomicappraisalaspartofaclinicaltrial.Althoughmodellingmethodsmaystillberequiredtoprovideacomprehensiveappraisal,thecharacterisingfeatureistheinclusionofaneconomiccomponenttothetrialandtheavailabilityofexperimentaldataonbothcostsandeffectsoftreatment.

Global HTA (GHTA)ThisprogrammecritiquesHTAindifferentcontexts,exploringvariationbetweenhigh-incomecountriesaswellaslookingin-depthastohowandwhydecisionmakinginhealthcaremaydifferamongstlow-andmiddle-incomecountries(LMICs).ThethemedrawsuponHEHTA’sresearchfromaglobalperspective,workingwithmajorstakeholdersandaspartoftheInternationalDecisionSupportInitiative.

Economics of Precision Medicine (EPM)ThisisHEHTA’snewestprogrammeanddirectlyalignswiththeCollegeofMedical,VeterinaryandLifeSciences(MVLS)roleasoneofthesixregionalcentresofexcellencecreatedbythePrecisionMedicineCatapult.The EPM programme focuses on understanding of the ‘strata’ofresponsesandthegeneticsofthediseases,and effective and cost-effective forms of treatment for differentpatientgroups,methodologicallyunpinnedbysubgroupanalyses.HEHTAishostinganMRCfundedresearchprojectinvestigatingtheuseoffullybayesianmethodstoincreasethereliabilityofsubgroupselection.Inaddition,weareinvestigatingtheimplicationsofprecisionmedicineforstudydesignandtechnologypricing.

Research Themes

21

Projectsawardedin2016

Projects Duration Total Project

Value (£)

Funder Research Theme

Extension of Follow-Up for High Risk Stage II Patients (additional 3 years) and Stage III Patients (up to year 3 follow-up) in the SCOT study.

2016-2018 294,839 NIHR DAMSEL

A woman-centred, tailored SMS-delivered multi-component intervention for weight loss and maintenance of weight loss in the postpartum period: intervention adaptation and pilot RCT

2016-2018 40,500 NIHR EPH

Evaluation of legislation to reduce the drink drive limit in Scotland: a natural experiment

2016-2018 75,000 NIHR ALDA, EPH

Evaluating graduated progress towards indoor smoke free prison facilities in Scotland

2016-2019 437,175 NIHR EEACT

Associations of blood biomarkers with cardiovascular disease and related cardiometabolic outcomes and risk prediction in the clinical setting: UK biobank

2016-2019 75,000 CHSS ALDA

Support to develop and deploy UAV technology for health commodity delivery

2016-2017 141,361 Bill and Melinda Gates Foundation

GHTA

International Decision Support Initiative (iDSI): Supporting Priority-Setting for Universal Health Coverage Phase II

2016-2018 193,175 Bill and Melinda Gates Foundation

GHTA, IPE

Improved metrics to assess impacts of coastal aquaculture farming on community well-being and nutritional status across farmed sea-food value chains in saline floodplains of Bangladesh

2016-2018 247,368 IMMANA GHTA

22

Projects Duration Total Project

Value (£)

Funder Research Theme

Glasgow molecular pathology Node (GMP) 2015-2018 3,481,464 MRC DAMSEL, EPM

Early signs monitoring to prevent relapse and promote wellbeing , engagement and recovery in schizophrenia

2015-2018 406,505 NIHR EEACT

Cardiac biomarkers and the prediction of CVD in Scotland

2015-2018 362,412 CSO DAMSEL

AIM (Ankle Injury Management) The AIM Trial is a pragmatic, multi-centre, individually randomised controlled equivalence study with parallel prospective economic evaluation comparing Close Contact Casting technique (CCC) to Open Reduction and Internal Fixation (ORIF)

2009-2017 70,000 NIHR EEACT

Barrett’s Oesophagus Surveillance versus endoscopy at need Study (BOSS): protocol and analysis plan for a multicentre randomized controlled trial

2009-2022 103,382 NIHR EEACT

A prospective randomised trial of myomectomy versus uterine artery embolisation (UAE) for women withuterine fibroids who wish to retain or improve their fertility (FEMME)

2011-2018 359,804 NIHR EEACT

Surgical Obesity Treatment Study (SCOTS) SurgiCal Obesity Treatment Study. A longitudinal cohort study of bariatric surgery across Scotland following all patients undergoing bariatric surgery in Scotland for a mean of 10 years. Outcomes will include mortality, diabetes incidence, diabetes complications, weight change, surgical complications, quality of life and fractures

2012-2026 2,036,689 NIHR EEACT

Woods in and around towns (WIAT) tackles the barriers people face to visiting and benefitting from woodlands regularly. The programme focuses on the location, accessibility and management of urban woodlands, to encourage more use from local people.

2012-2017 162,085 NIHR EPH

Social and Emotional Education Development 2012-2017 805,527 NIHR EPH

Ongoing projects

23

Projects Duration Total Project

Value (£)

Funder Research Theme

Three-Arm Randomised Control Trial for Mothers Indentified as Vulnerable in Pregnancy and their Babies who are at high risk of maltreatment

2013-2018 1,066,243 NIHR EEACT

BEAT-IT: A randomised controlled trial comparing a behavioural activation treatment for depression in adults with learning disabilities with an attention control.

2012-2017 783,006 NIHR EEACT

Cost-effectiveness of Theophylin for the treatment of COPD / (TWICS)

2012-2017 783,006 NIHR EEACT

E-Health Informatics Research Centres (E-HIRCs) - Farr Studentship

2012-2017 1,073,113 MRC ES, DAMSEL

A Randomised Controlled Trial of the Effectiveness of PDSAFE to prevent Falls among People with Parkinson’s Disease.

2013-2017 79,215 Parkinsons UK EEACT

Cancer and Venous Access (CAVA) randomised controlled trial of long-term venous access devices for the delivery of chemotherapy: ports versus tunnelled central lines versus percutaneous inserted central catheters

2013-2018 1,031,483 NIHR ES, IPE, DAMSEL

ADScAN:A Randomised Phase II study of Accelerated, Dose escalated, Sequential Chemo-radiotherapy in Non Small Cell Lung Cancer

2015-2021 28,431 CTAAC DAMSEL

CULPRIT SHOCK - Multivessel versus culprit lesion only percutaneous revascularization in patients with acute myocardial infarction complicated by cardiogenic shock’.

2013-2017 301,170 European Commission

EEACT

Effectiveness of a physical activity loyalty card for sustainable behaviour change

2014-2018 49,427 NIHR EPH

Early CDT Lung Test study 2012-2019 331,194 Oncimune Ltd EEACT

Oral Versus Intravenous Antibiotics (OVIVA) 2012-2017 66,837 NIHR EEACT

Ongoing projects continued

24

Ongoing projects continued

Projects Duration Total Project

Value (£)

Funder Research Theme

A randomised Phase 2 Trial of standard versus dose escalated radiotherapy in the treatment of pain in malignant pleural mesothelioma

2014-2017 130,312 Beatson Cancer Charity

EEACT

Helpmedoit!’ a web, app and text based intervention to facilitate social support to achieve and maintain health related change in physical activity and dietary behaviour

2015-2017 526,866 NIHR EPH, EEACT

Evaluation of the Healthy Start Voucher Scheme in UK: a natural experiment using the Growing Up in Scotland record linkage study and the Infant Feeding Survey.

2015-2017 556,452 NIHR EPH

Quantitative Fibronectin to help Decision making in women with symptoms of Preterm Labour – The QUIDS study

2015-2018 59,726 NIHR DAMSEL

A pilot evaluation of an intelligent liver diagnostic pathway

2015-2017 66,926 CSO DAMSEL

Reducing sedentary behaviour among older adults – The SITLESS Project

2015-2019 228,818 European Commission

EEACT, EPH

Technology enabled behavioural change as a pathway towards better self-management of CVD (PATHway)

2015-2018 209,927 European Commission

DAMSEL, EEACT

CRSU Complex reviews support unit 2015-2020 2,000,000 NIHR ES

The Football Fans in Training follow up RCT 2015-2017 341,619 NIHR EEACT, DAMSEL, EPH

Evaluation of the New Orleans Intervention model – BEST

2016-2020 2,751,519 NIHR EEACT, EPH

25

Projects Duration Total Project

Value (£)

Funder Research Theme

Symptoms, quality of life and place of care study 2015-201 91,981 BHF DAMSEL

Web based physiotherapy for people with multiple sclerosis

2014-2016 670,689 Multiple Sclerosis Society

DAMSEL, EEACT

Pragmatic Ischaemic Thrombectomy Evaluation (PISTE) trial: A randomised controlled trial of mechanicalthrombectomy in acute ischaemic stroke

2015-2016 926,979 NIHR DAMSEL, ES

Evaluation of the links worker programme in deep end general practices in Glasgow

2014-2016 300,000 NHS Health Scotland

EPH

International Decision Support Initiative (iDSI): Supporting Priority-Setting for Universal Health Coverage

2014-2016 56,455 NICE International GHTA

The effect of geography and socioeconomic status on health care costs at the end of life: implications for resource allocation and expenditure projections in Scotland

2014-2016 167,340 CSO ALDA

Reducing alcohol consumption in Obese Men - Development and Feasibility Testing of a Complex Community-based Intervention.

2014-2016 4,690 NIHR EEACT

A very early rehabilitation trial after stroke. A phase 3 multi-care randomised controlled trial (AVERT)

2013-2016 451,885 NIHR ES , EEACT

Selling Stroke Services in an International context 2014-2016 47,758 CHSS ES

Projectscompletedin2016

26

TheNIHRComplexReviewsSupportUnit(CRSU),acollaborationbetweentheUniversityofGlasgow,theUniversityofLeicesterandLondonSchoolofHygieneandTropicalMedicine,isledbyProfessorOliviaWu.CRSUisfundedbyNIHR(Projectnumber14/178/29)tosupportandencouragesuccessfuldeliveryofcomplexreviewsofimportancetotheUKNHS,whilstbuildingcapacityandcapabilitywithintheresearchcommunitythroughthesupportgiven.

During2016,theUnithasundertakenaprogrammeofevents to reach out to the NIHR research community andinparticulartheCochraneOrganisation.TwosuccessfulworkshopswereheldatTheCochraneUKandIrelandSymposium2016inBirminghaminMarch;‘MethodologicalChallengesinComplexReviews’and‘TheNIHRSystematicReviewsProgramme:OpportunitiesforGreaterImpact’.Afurthertwoworkshopsubmissions were accepted for the Cochrane UK and IrelandSymposium2017.Inaddition,attheinvitationof the Cochrane Dementia and Cognitive Improvement Group(CDCIG),CRSUranaworkshoponaccumulatingevidence,sequentialsynthesisandthechallengeofmultiplicityinSeptember,whichwasverywellreceived.

CRSUwaspleasedtoparticipateintheCochraneColloquium2016,inKoreainOctober,whereDrHilaryThomsonrepresentedthegroupattheposterpresentationsession.

InadditiontosupportingindividualCochraneReviewGroups,includingDementiaandCognitiveImprovementGroup,Gynaecological,Neuro-oncologicalandOrphanCancersGroup,HeartGroupandAirwaysGroup,theUnithasworkedcloselyonsupportingeightfullapplicationstotheNIHRCochraneProgrammeGrantsScheme.

ThefirstofaseriesofSeminarswithCuttingEdgeMethods,‘Aggregatingevidenceaboutthepositiveandnegativeeffectsoftreatmentsusingacomputationalmodelofargument’,washeldattheUniversityofLeicesterinMarch2016.

Overall,CRSUhashadachallengingandfulfillingyear,buildingasuccessfulworkingrelationshipwiththeNIHRresearchcommunityinsupportingtheUKNHStodeliverclinically-andcost-effectiveservicesthatareevidence-based.ForfurtherinformationonCRSUseeourwebsiteatwww.nihrcrsu.org

Moira Aitken, CRSU Project Manager

NIHRComplexReviewSupportUnit(CRSU)

27

A Researcher’s Perspective

28

CaoimheRyantalksaboutworkingatHEHTA

Tell us a little about your background Mybackgroundisinpsychology.AsanundergraduateIstudiedpsychologyatUniversityCollegeDublin.IearnedmyMScinsocialandculturalpsychologyattheLondonSchoolofEconomics,afterwhichIworkedforanumberofyearsinhealthpsychologyresearchattheUniversityofStirlingandlatertheUniversityofStrathclyde.IeventuallyreturnedtostudyandlastyeargraduatedfromtheUniversityofStAndrewswithaPhDinsocialpsychology.

What attracted you to HEHTA?

Iwasinterestedinsteppingoutofpsychologytoworkinamultidisciplinarycontextandgainexperienceinappliedresearch.IwasparticularlydrawntoHEHTA’s‘Incorporating Patient Perspectives and Experiences’ researchtheme.Withinthistheme,mycurrentworkispartofanRCTthataimstoevaluatetheclinical-andcost-effectivenessofvenousaccessdevices.Myroleistosupportthisevaluationwithaqualitativeinvestigationofpatientandclinicianexperienceswiththesedevices.Iseealotofvalueinapproachestohealthtechnologyassessment that incorporate subjective experiences of healthinterventions.

What aspects of the work you do at HEHTA do you think will help your future career? Workingaspartofalarge-scalemulti-siteRCThasbeenveryinstructive.I’velearnedalotabouthowtrialsaremanagedandcoordinated,abouttheissuestrialsface,abouttherolesoftrialmanagers,clinicalresearchers,stakeholders,andpatients,andaboutwhatittakestorunasuccessfultrial.Inparticular,Ithinkthatunderstandingthewaysinwhichqualitativeresearchcancontributetosuchtrialsaddrealvaluewillbehelpfulinmyfuturecareer.

Do you enjoy Glasgow as a place to live and work? I’velivedinGlasgowformanyyears–eventhroughoutmystudiesatStAndrewsUniversity–andIfeelveryathomehere.Tome,Glasgowfeelsverydowntoearth,open,andprogressive.It’salivelyandinterestingcity,andaneasyplacetolive.Foranyonewhoenjoystheoutdoors,Glasgowisideal.There’saplethoraofgreatparksdottedaroundthecity,thebeautifulCampsieFellsarerightonyourdoorstep,andLochLomondandtheTrossachsareastone’sthrowbeyondthat.

29

Teaching and Supervision

30

MSc HTA programme

HTA: Policy and Principles

Jim Lewsey HannahHesselgreaves OliviaWu NickiBoyer Emma McIntosh ZahidQuayyum KathleenBoyd NicolaMcMeekin EleanorGrieve Yiqiao Xin

Health Economics for HTA

KathleenBoyd ClaudiaGeue Jim Lewsey Emma McIntosh NicolaMcMeekin EleanorGrieve

Outcome Measurement and Valuation for HTA

Emma McIntosh Yiqiao Xin EleanorGrieve

Qualitative Methods in HTA

HannahHesselgreaves

Decision Analytic Modelling Methods

Andrew Briggs OliviaWu KathleenBoyd NeilHawkins

Throughout2016HEHTAstaffalsocontributedtoteachingonnumerousotherprogrammesincludingtheMastersinPublicHealth,MBChB,MScHumanNutrition,MScGlobalMentalHealth,MScCancerStudies,MScGlobalHealthandManagement(UniversityofAberdeen).

Claudia Geue and Mohsen Rezaiehemami supervised MPH student Naomi Ferguson

Projecttitle:‘Cost-effectivenessoftreatingHepatitisCinSeychelles’

Olivia Wu and Yiqiao Xin supervised MPH student Jenny Harbour

Projecttitle:‘Comparativeeffectivenessofinterventionsforalcoholicliverdisease:asystematicreviewandnetworkmeta-analysis’

Kathleen Boyd and Nicola McMeekin supervised MSc HTA student Evidence Nyamadzawo

Projecttitle:‘Mindfulnessbasedcognitivebehaviouraltherapydecisionmodel’

Janet Bouttell and Neil Hawkins supervised MSc HTA student Dmitry Ponomarev

Projecttitle:‘Impactofpotentialbiomarkerinovariancancer’

Teaching Supervision

31

Continuing Professional Development

32

Online distance learning

In2016,HEHTAlaunchedsomeofitsMScmodulesasonlineCPDcoursesforthefirsttime:

• HealthEconomicsforHTA • HTA:policyandprinciples • OutcomemeasurementandvaluationforHTA • QualitativeresearchmethodsinHTA

Healthpractitionersandresearchersfromallovertheworldwereabletobenefitfromourfirst-classteachingmaterialandgainexperttraininginavarietyofnewskillsatafractionofthecostofattendingaface-to-facecourse.Participantsconnectwithfellowstudentsandtutorsthroughourvirtuallearningenvironmentwheretheyhaveaccesstomanydifferentlearningresourcesincludingrecordedlectures,videosandinteractivequizzes.Teachingisresearch-ledandthecourseshavebeendevelopedtoreflectthelatestacademicresearchandup-to-datechallengesinHTAdecision-making.

Themodulescompriselecturesandaccompanyingpracticalexercises.Thecoursesplacegreatemphasisonsupportandinteraction.Eachweektheacademicleadwilldirectandobservetheforumdiscussionandrespondtoparticipantquestionsaboutthecoursecontent.Theonlinecoursehastheaddedbenefitofbeingflexiblearoundparticipants’schedules,makingitanidealwaytoupskill.

Face-to-face

Decision Analytic Modelling Methods for Economic Evaluation

Firstrunin2007thiscoursehasprovedextremelypopular,withnumbersincreasingyear-on-year.Thecoursehastwolevels:atwo-dayfoundationlevelcoursefollowedbyathree-dayadvancedlevelcourse.

Thefoundationscourseisaimedathealtheconomistsandhealthprofessionalswithexperienceofhealtheconomics,whowishtodevelopskillsandknowledgeindecisionanalysisforpurposesofcosteffectivenessanalysis.Theadvancedcourseisaimedatthosewithexpereinceofhealtheconomicswhowishtolearnaboutrecentmethodologicaldevelopmentsincost-effectivenessanalysis.

In2016wehad39participantsonourFoundationscourseand63ontheAdvancedcourse.

‘Best course in health economics modelling out there! Excellent teachers, tutors, material and experience’

‘Very useful course, would recommend it to everyone interested in gaining advanced knowledge in economic modelling.’

‘The most useful health economics course I have attended!’

‘Excellent thorough introduction to HEOR’

‘...gives you a great overview about different modelling techniques’

‘Top notch course on economic modelling’

‘The course was very well organised, with really helpful administration staff. It was led by highly qualified lecturers.’

‘Great online course, that makes you feel like you are actually in a classroom rather than on your own.’

33

Publications

34

Baba C,KearnsA,McIntosh E,TannahillC,Lewsey J. Is empowermentaroutetoimprovingmentalhealthandwellbeinginanurbanregeneration(UR)context?UrbanStudies.2016;54(7):1619-1637.

Baba C.Valuingthehealthandwellbeingaspectsofcommunityempowerment in an urban regeneration context using economic evaluationtechniques.PhDThesis,UniversityofGlasgow.2016.

BalaliM,KamalidehghanBFM,AhmadipourF,AshkezariMD,Hemami MR,ArabzadehH,etal.AssociationofnuclearandmitochondrialgeneswithaudiologicalexaminationsinIranianpatientswithnonaminoglycosideantibiotics-inducedhearingloss.TherapeuticsandClinicalRiskManagement.2016;12:117-28.

BeckerU,Briggs A,MorenoSG,RayJA,NgoP,SamantaK.Cost-EffectivenessModelforChemoimmunotherapyOptionsinPatientswithPreviouslyUntreatedChronicLymphocyticLeukemiaUnsuitableforFull-DoseFludarabine-BasedTherapy.ValueHealth.2016;19(4):374-82.

Bouttell J, Lewsey J, Geue C,AntonyG,Briggs AH,McCartneyG,etal.TheScottishAlcoholicLiverdiseaseEvaluation:APopulation-LevelMatchedCohortStudyofHospital-BasedCosts,1991-2011.PLoSOne.2016;11(10):e0162980.

Boyd KA, Briggs AH,BauldL,SinclairL,TappinD.Arefinancialincentivescost-effectivetosupportsmokingcessationduringpregnancy?Addiction.2016;111(2):360-70.

Boyd KA,TappinDM,BauldL.Cost-effectivenessoffinancialincentivesforsmokingcessationinpregnancy.Addiction.2016;111(6):115-7.

Boyer NR,MillerS,ConnollyP,McIntosh E.PavingthewayfortheuseoftheSDQineconomicevaluationsofschool-basedpopulationhealthinterventions:anempiricalanalysisoftheexternalvalidityofSDQmappingalgorithmstotheCHU9Dinaneducationalsetting.QualityofLifeResearch.2016;25(4):913-23.

Briggs AH.AViewfromtheBridge:HealthEconomicEvaluation—AValue-BasedFramework?HealthEconomics.2016;25(12):1499-502.

Briggs AH,NugentR.Economicevaluationsinlow-andmiddle-incomecountries:Methodologicalissuesandchallengesforpriority-setting.HealthEconomics.2016;25:6-8.

BrockPM,FornaceKM,Parmiter M,CoxJ,DrakeleyCJ,FergusonHM,etal.Plasmodiumknowlesitransmission:integratingquantitativeapproachesfromepidemiologyandecologytounderstandmalariaasazoonosis.Parasitology.2016;143(4):389-400.

EganM,KearnsA,KatikireddiSV,CurlA,Lawson K,TannahillC.Proportionateuniversalisminpractice?Aquasi-experimentalstudy(GoWell)ofaUKneighbourhoodrenewalprogramme’simpactonhealthinequalities.SocialScience&Medicine.2016;152:41-9.

FisherA,AndreassonA,ChrysosA,LallyJ,MamasoulaC,ExleyC,etal.AnobservationalstudyofDonorExVivoLungPerfusioninUKlungtransplantation:DEVELOP-UK.HealthTechnolAssess.2016;20(85):1-276.

Geue C, Lewsey JD,MacKayDF,AntonyG,FischbacherCM,MuirieJ,etal.ScottishKeepWellhealthcheckprogramme:aninterruptedtimeseriesanalysis.JEpidemiolCommunityHealth.2016;70(9):924-29.

Geue C, Wu O,LeylandA,Lewsey J,QuinnTJ.Geographicvariationofinpatientcarecostsattheendoflife.AgeandAgeing.2016;45(3):376-81.

GurusamyKS,PallariE,Hawkins N,PereiraSP,DavidsonBR.Managementstrategiesforpancreaticpseudocysts.CochraneDatabaseSystRev.2016;4:CD011392.

HunterRF,BrennanSF,TangJ,SmithOJ,MurrayJ,TullyMA,etal.Effectivenessandcost-effectivenessofaphysicalactivityloyaltyschemeforbehaviourchangemaintenance:aclusterrandomisedcontrolledtrial.BMCPublicHealth.2016;16(1):1-12.

KeshavarzK,KebriaeezadehA,AlavianSM,AkbariSariA,Rezaei Hemami M,LotfiF,etal.ACost-UtilityandCost-EffectivenessAnalysisofDifferentOralAntiviralMedicationsinPatientsWithHBeAg-NegativeChronicHepatitisBinIran:AnEconomicMicrosimulationDecisionModel.HepatitisMonthly.2016;16(9):e37435.

LawsonKD,Lewsey JD,FordI,FoxK,RitchieLD,Tunstall-PedoeH,etal.Acardiovasculardiseasepolicymodel:part2-preparingforeconomicevaluationandtoassesshealthinequalities.OpenHeart.2016;3(1):e000140.

LeeMM,PetrieMC,RocchiccioliP,SimpsonJ,JacksonC,BrownA,etal.Non-invasiveversusinvasivemanagementinpatientswithpriorcoronaryarterybypasssurgerywithanon-STsegmentelevationacutecoronarysyndrome:studydesignofthepilotrandomisedcontrolledtrialandregistry(CABG-ACS).OpenHeart.2016;3(1):e000371.

LewisSC,BhattacharyaS, Wu O,VincentK,JackSA,CritchleyHO,etal.GabapentinfortheManagementofChronicPelvicPaininWomen(GaPP1):APilotRandomisedControlledTrial.PLoSOne.2016;11(4):e0153037.

LukerJA,CraigLE,BennettL,ElleryF,LanghorneP,Wu O,etal.Implementingacomplexrehabilitationinterventioninastroketrial:aqualitativeprocessevaluationofAVERT.BMCMedicalResearchMethodology.2016;16(1):52.

McAuleyA,Bouttell J,BarnsdaleL,MackayD,Lewsey J,HunterC,etal.Evaluatingtheimpactofanationalnaloxoneprogrammeonambulanceattendanceatoverdoseincidents:acontrolledtimeseriesanalysis.Addiction.2016;112(2):301-8.

McCartneyG,Bouttell J,CraigN,CraigP,GrahamL,LakhaF,etal.Explainingtrendsinalcohol-relatedharmsinScotland,1991-2011(I):theroleofincomes,effectsofsocio-economicandpoliticaladversityanddemographicchange.PublicHealth.2016;132:13-23.

McCartneyG,Bouttell J,CraigN,CraigP,GrahamL,LakhaF,etal.Explainingtrendsinalcohol-relatedharmsinScotland1991-2011(II):policy,socialnorms,thealcoholmarket,clinicalchangesandasynthesis.PublicHealth.2016;132:24-32.

McIntosh E,GrayA,DanielsJ,GillS,IvesN,JenkinsonC,etal.Cost-utilityanalysisofdeepbrainstimulationsurgeryplusbestmedicaltherapyversusbestmedicaltherapyinpatientswithParkinson’s:EconomicevaluationalongsidethePDSURGtrial.MovementDisorders:2016;31(8):1173-78.

MealingS,WoodsB,Hawkins N,CowieMR,PlummerCJ,AbrahamWT,etal.Cost-effectivenessofimplantablecardiacdevicesinpatientswithsystolicheartfailure.Heart.2016;102(21):1742-49.

35

MercerSW,FitzpatrickB,GuthrieB,FenwickE,Grieve E,LawsonK,etal.TheCAREPlusstudy–awhole-systeminterventiontoimprovequalityoflifeofprimarycarepatientswithmultimorbidityinareasofhighsocioeconomicdeprivation:exploratoryclusterrandomisedcontrolledtrialandcost-utilityanalysis.BMCMedicine.2016;14(1):1-10.

MinnisH,Boyd KA,FitzpatrickB,FordeM,GillbergC,HendersonM,McMahonL,McIntosh,Eetal.‘Protocol15PRT/6090:TheBestServicesTrial(BeST?):Effectivenessandcost-effectivenessoftheNewOrleansInterventionModelforInfantMentalHealth’.TheLancet. http://www.thelancet.com/protocol-reviews/15PRT-6090

MoiseN,HuangC,RodgersA,Kohli-Lynch CN,TzongKY,CoxsonPG,etal.ComparativeCost-EffectivenessofConservativeorIntensiveBloodPressureTreatmentGuidelinesinAdultsAged35-74Years:TheCardiovascularDiseasePolicyModel.Hypertension.2016;68(1):88-96.

NahvijouA,DaroudiR,TahmasebiM,AmouzegarHashemiF,Rezaei Hemami M,AkbariSariA,etal.Cost-EffectivenessofDifferentCervicalScreeningStrategiesinIslamicRepublicofIran:AMiddle-IncomeCountrywithaLowIncidenceRateofCervicalCancer.PLoSOne.2016;11(6):e0156705.

ParkinsonJ,MintonJ,Lewsey J, Bouttell J,McCartneyG.RecentcohorteffectsinsuicideinScotland:alegacyofthe1980s?JournalofEpidemiologyandCommunityHealth.2016;71(2):194-200.

SaffariN,Salmanzadeh-AhrabiS,Abdi-AliA,Rezaei-Hemami M.AcomparisonofantibioticdisksfromdifferentsourcesonQuicolorandMueller-Hintonagarmediainevaluationofantibacterialsusceptibilitytesting.IranianJournalofMicrobiology.2016;8(5):307-11.

SheppardL,DeweyH,BernhardtJ,CollierJM,ElleryF,ChurilovL,etal.EconomicEvaluationPlan(EEP)forAVeryEarlyRehabilitationTrial(AVERT):Aninternationaltrialtocomparethecostsandcost-effectivenessofcommencingoutofbedstandingandwalkingtraining(veryearlymobilization)within24hofstrokeonsetwithusualstrokeunitcare.InternationalJournalofStroke.2016;11(4):492-4.

StadlerN,ShangA,BoschF,Briggs AH,GoedeV,BerthierA,etal.ASystematicReviewandNetworkMeta-AnalysistoEvaluatetheComparativeEfficacyofInterventionsforUnfitPatientswithChronicLymphocyticLeukemia.AdvancesinTherapy.2016;33(10):1814-30.

ThompsonJC,QuigleyJM,HalfpennyNJ,ScottDA,Hawkins N.ImportanceandmethodsofsearchingforE-publicationsaheadofprintinsystematicreviews.Evidence-BasedMedicine.2016;21(2):55-9.

TiffinPA,MwandighaLM,PatonLW,Hesselgreaves H,McLachlanJC,FinnGM,etal.PredictivevalidityoftheUKCATformedicalschoolundergraduateperformance:anationalprospectivecohortstudy.BMCMed.2016;14(1):140.

TremblayG,LivingsC,CroweL,KapetanakisV,Briggs AH.Determinationofthemostappropriatemethodforextrapolatingoverallsurvivaldatafromaplacebo-controlledclinicaltrialoflenvatinibforprogressive,radioiodine-refractorydifferentiatedthyroidcancer.ClinicoEconomicsandOutcomesResearch.2016;8:323-33.

WildmanJ,McMeekin P, Grieve E, Briggs AH.Economicevaluationofintegratednewtechnologiesforhealthandsocialcare:Suggestionsforpolicymakers,usersandevaluators.SocialScience&Medicine.2016;169:141-8.

WillettK,KeeneDJ,MistryD,NamJ,TuttonE,HandleyR,etal.CloseContactCastingvsSurgeryforInitialTreatmentofUnstableAnkleFracturesinOlderAdults:ARandomizedClinicalTrial.JAMA.2016;316(14):1455-63.

Williams C, Lewsey J, Briggs, AH.Mackay,D.Estimationofsurvivalprobabilitiesforuseincost-effectivenessanalysis:acomparisonofamulti-statemodellingsurvivalanalysisapproachwithpartitionedsurvivalandMarkovdecision-analyticmodelling.MedicalDecisionMaking.2016;37(4):427-39.

Williams C, Lewsey, J, Briggs, AH.Cost-effectivenessanalysisinRusingamulti-statemodellingsurvivalanalysisframework:Atutorial.MedicalDecisionMaking.2016;37(4):340-52.

Wu O, Boyd K,PaulJ,McCartneyE,Ritchie M,MellonD,etal.Hickmancatheterandimplantableportdevicesforthedeliveryofchemotherapy:aphaseIIrandomisedcontrolledtrialandeconomicevaluation.BrJCancer.2016;114(9):979-85.

Xin Y,MansonJ,Govan L,HarbourR,BennisonJ,WatsonE,etal.PharmacologicalregimensforeradicationofHelicobacterpylori:anoverviewofsystematicreviewsandnetworkmeta-analysis.BMCGastroenterology.2016;16(1):80.

Xin Y, McIntosh E.Assessmentoftheconstructvalidityandresponsivenessofpreference-basedqualityoflifemeasuresinpeoplewithParkinson’s:asystematicreview.QualityofLifeResearch.2016;26(1):1-23.

36

Presentations

KathleenBoyd,‘ADSCaN:ARandomisedPhaseIIstudyofAccelerated,Doseescalated,SequentialChemo-radiotherapyinNon-SmallCellLungCancer(NSCLC)’,14thAnnualBritishThoracicOncologyGroup(BTOG)Conference2016,Dublin,Ireland,28January2016

EleanorGrieve,‘EvaluationtheimpactofHTAand‘betterdecision-making’onhealthoutcomes’,CentreforHealthEconomicsseminars2016,York,UK,3March2016

AndrewBriggs,‘Theeconomicsoftestinganddiagnosisincancer:quantifyingthevalueofinformation’,HORGSeminarSeries,MemorialSloanKetteringCancerCentre,NewYork,USA,4March2016

CiaranKohli-Lynch,‘Long-termbenefitsofbloodpressureloweringinyoungadulthood:acomputersimulationstudy’,AmericanHeartAssociationEpidemiology/Lifestyle2016ScientificSessions,Phoenix,USA,7March2017

HannahHesselgreaves,‘Factorsaffectingrecruitmenttohigherspecialtytraining:aquestionnairestudy’,RoyalCollegeofPhysiciansMedicine(RCP)annualconference,Harrogate,UK,15-16March2016

CamillaBaba,‘ValuingCommunityEmpowermentinanUrbanRegenerationContextasanalternativepathwaytohealthgains:aDiscreteChoiceExperiment’,13thInternationalConferenceonUrbanHealth,SanFrancisco,USA,3April2016

HannahHesselgreaves,CAVATrialqualitativeresearch,PortCourse,UniversityofGlasgow,7April2016

CamillaBaba,‘ValuingCommunityEmpowermentinanUrbanRegenerationContextasanalternativepathwaytohealthgains:aDiscreteChoiceExperiment’,CentreforHealthEconomics,York,UK,12May2016

OliviaWuandNeilHawkins,‘AFrameworkForAssessingEvidenceForHTAInContext’–paneldiscussion,HTAi2016,Tokyo,Japan,13May2016

OliviaWu,‘AQualityStandards:ImplementingValue-BasedHTADecisionsForUniversalHealthCoverage’–paneldiscussion,HTAi2016,Tokyo,Japan,14May2016

EmmaMcIntosh,‘TheEconomicsofPrevention’,PublicHealthAnnualResearchandPracticeConference2016,Belfast,UK,8June2016

MohsenRezaei,‘CostEffectivenessOfDifferentCervicalScreeningStrategiesInI.R.Iran:AMiddle,IncomeCountryWithALowIncidenceRateOfCervicalCancer’,IARCConference-GlobalCancer:Occurrence,Causes,andAvenuestoPrevention,Lyon,France,8June2016

37

JimLewsey,‘TheimpactoftheAlcoholActonalcohol-relatedhealthharmsinScotland’,SocietyofMedicalDecisionMaking(SMDM)Europe2016,London,12June2016

YiqiaoXin,JimLewseyandEmmaMcIntosh,‘BroadeningtheevaluativescopeofqualityoflifeinParkinson’s:TestingtheconstructvalidityoftheICECAP-Oinstrument’,20thInternationalcongressofParkinson’sdiseaseandmovementdisorders,Berlin,Germany,20June2016

NickiBoyer,‘Populationhealtheconomicevaluationoftheschool-basedRootsofEmpathyprogrammeinNorthernIreland’,HESG2016,GranCanaria,Spain,21June2016

YiqiaoXin,‘TestingtheconstructvalidityoftheICECAP-OinstrumentinParkinson’sandexploringitsrelationshipwiththeEQ-5D-3LandtheParkinson’sspecificqualityoflifequestionnairethePDQ-39’,HESG2016,GranCanaria,23June2016

JoseRobles-Zurita,‘Randomnessbeliefsanddecisionsonriskymedicaltreatments’,IAREP/SABE2016Conference“BehaviouralInsightsinResearchandPolicyMaking”,Wageningen,Netherlands,7July2016

CamillaBaba,‘ValuingCommunityEmpowermentinanUrbanRegenerationContextasanalternativepathwaytohealthgains:aDiscreteChoiceExperiment’PublicHealthPhDsymposium,JohnMooreUniversity,Liverpool,UK,7July2016

ClaudiaGeue,‘DeterminantsofhealthcareexpenditureattheendoflifeforcancerpatientsinScotland’,EuHEA2016,Hamburg,Germany,14July2016

ClaudiaGeue,‘TheScottishKeepWellHealthCheckprogramme:aninterruptedtimeseriesanalysis’,EuHEA,Hamburg,Germany,15July2016

NickiBoyer,‘Populationhealtheconomicevaluationoftheschool-basedRootsofEmpathyProgrammeinNorthernIreland’,EuHEA2016,Hamburg,Germany,15July2016

GiorgioCiminata,‘TheinpatientandsocialcarecostofatrialfibrillationinScotland’,EuHEA2016,Hamburg,Germany,15July2016

NicolaMcMeekin,‘Canconceptualmodellingmethodologyfromotherdisciplinesinformconceptualmodellingmethodologyineconomicevaluationsofhealthcare?’,EuHEA2016,Hamburg,Germany,15July2016

OliviaWu,‘Thresholdsanddecision-making:howaredecisionsmadeataNICETechnologyAppraisalCommittee?’,CientificaIVFaff,Salvador,Brazil,27July2016

OliviaWu,‘AdoptionofnewtechnologiesforrarediseaseintheUK’,CientificaIVFaff,Salvador,Brazil,28July2016

OliviaWu,‘UsingQualityAdjustedLifeYears(QALYs)inEconomicEvaluation’,CientificaIVFaff,Salvador,Brazil,29July2016

ClaudiaGeue,‘Theimpactofsocialcareexpenditureattheendoflife:anovellinkagestudyinScotland’,InternationalPopulationDataLinkageConference,Swansea,UK,24August2016

GiorgioCiminata,‘TheinpatientandsocialcarecostofatrialfibrillationinScotland’,InternationalPopulationDataLinkageConference,Swansea,UK,24August2016

MohsenRezaei,‘Acost-utilityanalysisofdifferentantiviralmedicineregimensinpatientswithchronichepatitiscvirusgenotype1infection:aneconomicmicro-simulationdecisionmodel’,ISPOR7thAsia-PacificConference,Singapore,4September2016

JimLewsey,‘Developmentofanalcoholpolicymodelthatpredictslifeyears,QALYs,andhealthcarecostsaccountingforalcoholusedisorder’,ISPOR7thAsia-PacificConference,Singapore,5September2016

EleanorGrieve,‘Frompriority-settingdecisionstohealthimpact:newexplorationsofacomplextranslationprocess’,InternationalSocietyonPrioritiesinHealthCareconference,Birmingham,UK,7September2016

ClaudiaGeue,‘WorkplanfortheHealthEconomicsWorkPackage’,ECHorizon2020PATHwayConsortiummeeting,Thessaloniki,Greece,20September2016

OliviaWu,‘HowNICEappraisalsupportstherationalaccesstonewandexpensivemedication’,45thESCPSymposiumonClinicalPharmacy,Oslo,Norway,3October2016

AndrewBriggs,‘Impactofeconomiccrisesonhealthcarefunding’,MakeBetterSummit,Berlin,Germany,7October2016

CiaranKohli-Lynch,‘Signallingdemand:PCSK9InhibitorsforStatinIntolerantIndividuals’,SMDMNorthAmerica,23October2016

CiaranKohli-Lynch,‘PrioritisingIndividualsforPreventiveStatinTherapy:BeyondTen-YearRisk’,SMDMNorthAmerica,23October2016

MoiraAitken,‘NIHRCRSU–theNationalInstituteforHealthResearchComplexReviewsSupportUnit:supportingsuccessfuldeliveryofcomplexreviews’,CochraneColloquium,GrandHilton,Seoul,Korea,23October2016

JanetBouttell,‘MethodsofEarlyHealthTechnologyAssessmentinPrecisionMedicine’,GMPNodeAnnualSymposium,Glasgow,UK,24October2016

JanetBouttellandJimLewsey‘Age,PeriodandCohort(APC)effectsinsuicideinScotland’,FacultyofPublicHealthConference,Dunblane,Scotland,27October2016

OliviaWuandNeilHawkins,‘Meta-Analysis&SystematicLiteratureReview’,ISPOREurope2016,Vienna,Austria,29October2016

AndrewBriggs,‘CollectingHealth-StateUtilityEstimatesforEconomicModelsinClinicalStudies’,ISPOREurope2016,Vienna,Austria,29October2016

NeilHawkins,‘DevelopmentofConceptualModels’,ISPOREurope2016,Vienna,Austria,29October2016

GiorgioCiminata,‘Theprescribing,inpatient,outpatientandsocialcarecostsassociatedwithatrialfibrillationinScotland’,ISPOREurope2016,Vienna,Austria,29October2016

38

NeilHawkinsandOliviaWu,‘Theevolvingroleofreal-worlddatainevidencesynthesistomeetdemandsforevidence-basedmedicine’,ISPOREurope,Vienna,Austria,30October2016

AndrewBriggs‘UnderstandingSurvivalModellingwithApplicationtoHTA’,ISPOREurope2016,Vienna,Austria,30October2016

AndrewBriggs,‘IntroductiontotheEconomicAnalysisofDiagnostics’,ISPOREurope2016,Vienna,Austria,30October2016

OliviaWu,‘LostinTranslation’,ISPOREurope2016,Vienna,Austria,30October2016

NeilHawkins,‘SynthesisofBinaryOutcomeDataontheLog-OddsandAbsoluteRiskScales–ACaseStudyinChronicHepatitis’,ISPOREurope2016,Vienna,Austria,31October2016

ClaudiaGeue,‘HealthEconomicsinEndofLifeCare’,ICAMs–InstituteofCardiovascularandMedicalSciences,Glasgow,UK3November2016

JoseRobles-Zurita,‘Randomnessbeliefsanddecisionsonriskymedicaltreatments’,MDXExperimental/BehavioralSeminarSeries,DepartmentofEconomicsatMiddlesexUniversityLondon,9November2016

AndrewBriggs,‘HealthTechnologyAssessment’,Biogen,Copenhagen,Denmark,28November2016

GiorgioCiminata,‘Theprescribing,inpatient,outpatientandsocialcarecostsassociatedwithatrialfibrillationinScotland’,UKStrokeForum,Liverpool,28November2016

39

Membership of Expert Bodies

40

Andrew Briggs Editor,HealthEconomics

AssociateEditor,ValueinHealth

TrialSteeringCommittee:NOSH

TrialSteeringCommittee:DISCHARGE

Eleanor Grieve MemberofESRCGlobalChallengesResearchFundPeerReviewGroup

Emma McIntosh MemberofEditorialBoardforBMCMedicalResearchMethodology

AdvisoryBoardMember,CSONationalBurdenofDisease,InjuriesandriskFactors

AdvisoryBoardMember,ScottishImmunisationProgramme-Epidemiology&Surveillance Reference Group

AdvisoryBoardMember,MultipleSclerosisTrust:GeneratingEvidenceinMSServices

AdvisoryBoardMember,Evaluationoftheimpactoftobaccocontrolmassmediacampaignson quittingbehaviour,smokingprevalenceandsmoking-relatedhealthoutcomes

BoardMember,GlasgowCentreforPopulationHealth

DatamonitoringCommittee2011-2015:NIHRPacesTrial

NationalHealthEconomistsInterestGroup

Jim Lewsey CharteredStatistician,RoyalStatisticalSociety

CharteredScientist,TheScienceCouncil

MemberofEvidenceReviewCommitteeforScottishHealthTechnologiesGroup/Healthcare ImprovementScotland

Kathleen Boyd AdvisoryBoardMember,BeatsonWestofScotlandCancerCareClinicalTrialsUnit:In-houseTrials

Advisory Board

Neil Hawkins MemberofMedicalSectionCommitteeoftheRoyalStatisticalSociety

Olivia Wu Member of the NIHR Systematic Reviews Programme Advisory Group

Member of the NIHR HTA Evidence Synthesis Board

MemberoftheNationalInstituteofHealthandCareExcellenceTechnologyAppraisalCommittee

41

42

43

Health Economics and Health Technology Assessment (HEHTA)InstituteofHealth&Wellbeing

UniversityofGlasgow 1LilybankGardens,GlasgowG128RZ

Telephone:01413304010 www.gla.ac.uk/hehta

Email:ihw-hehta@glasgow.ac.uk Twitter:@HEHTAGlasgow

©UniversityofGlasgow2017 ProducedanddesignedbyMVLSDesignandCommunication,UniversityofGlasgow

TheUniversityofGlasgow,charitynumberSC004401