Controlled Environment, Laboratory and Pharmaceutical Equipment Solutions for Life Science, Pharmaceutical, Biomedical and Industrial Research Applications

Worldwide Edition, 2013/2014

Guide to Esco Products and Services

Esco Product Guide

Guide to Esco Products and Services

Corporate Profile ................................................................. 3

Life Science Sample Preparation

Biological Safety Cabinets ................................................................7

Laminar Flow Clean Benches ............................................................8

Lab Animal Research Products .........................................................9

PCR Cabinets, Microplate Shakers and Freeze Dryers...................10

Sample CultivationCO2 Incubators ................................................................................11

Sample AnalysisPCR Thermal Cyclers .......................................................................12

Sample StorageUltra-low Temperature Freezers ....................................................13

Laboratory Refrigerators and Freezers ..........................................14

SoftwareVoyager ...........................................................................................15

Chemical ResearchDuctless Fume Hoods ......................................................................16

Laboratory Fume Hoods .................................................................17

Fume Hoods Accessories .................................................................18

Assisted Reproductive Technology (ART)ART Workstations ...........................................................................19

Multi-room Incubators ...................................................................20

Pharmaceutical Equipment ........................................... 21

General EquipmentLaboratory Ovens and Incubators ..................................................22

After Sales Services .......................................................... 23

2

Table of Contents:

• Foundedin1978.

• Aleaderinthedevelopmentofcontrolledenvironment,

laboratoryandpharmaceuticalequipmentsolutions.

• Aworldleaderinbiologicalsafetycabinets.

• Escohasestablishedofficesin13countriessuchasBahrain,China,India,Japan,Korea,Malaysia,

Philippines,Singapore,SouthAfrica,UK,US,Indonesia

andVietnamandiscontinuallyexpanding.

• NorthAmericanfacilitiesinPennsylvania;sales,

service,logisticsforUS&Canada.

• Grouptotalofmorethan600employees.

• Distributorsinmorethan110countries.

• Productsindependentlytestedtointernationalstandards.

• LargeR&Dinvestments,worldleadingtechnologies.

• State-of-the-artproduction;verticallyintegratedmanufacturingfloorspace.

• Worldwideserviceplayedoutoverageographicexpanse

sobroadthatthesunneversetsonwhatwedo.

Welcome to Esco

Pictured: Esco Micro Pte. Ltd. is headquartered in Singapore, a modern city state located in Southeast Asia with a population of more than 4 million. From Singapore, Esco manages operations throughout the world.

Esco’s Vision is to provide enabling technologies for scientific discoveries to make human lives healthier and safer.

Pictured: Esco's state-of-the-art primary manufacturing facility, the world's largest manufacturing base for LAF/BSC cabinets.

3

Esco Product Guide

2004

2010

2012

4

Escomanufacturesthefirstlaminarflowcleanbench;designsandbuildsitsfirstmicroelectronicsClass

10,000cleanroomforSiemensCorporation.

1978

2001

2009

EscoearnsfirstEN12469certificationforbiologicalsafetycabinet.

TheChineseFoodandDrugAdministrationinvitesEscotoparticipateinajointcommitteetodeveloptheNationalStandardforBiologicalSafetyCabinets.

EscolaunchesCelCulture®NewCO2incubator.

EscolaunchestheEscoMedicalDivision,providingworldclassART/IVFsolutions

worldwide,withafocusonthenewMiri®Multi-·roomIncubator.

Escomanufacturedthelowestnoise(45dBA)BSCintheworldforalarge

installationinKarolinskaInstitute,Sweden.

A Tradition of Quality

Escoexpandsdistributiontopharmaceutical,lifescience,biotechnologyandmedicalresearchmarkets.

1990

Isotherm®-newLaboratoryOvensandIncubators.

PharmaconTMnewDownflowBooths.

1984 EscodesignsandbuildsClass100laundryandbecomesthefirstcompanyintheregiontoenterthecleanroomlaundrybusiness.

Swift®MaxProandMiniPronewgenerationPCRthermalcyclers

2011

2013

EscolaunchesLexicon®rangeofUltra-lowTemperatureFreezers.

EscolaunchesAirstream®G3ClassII,thegreenestlownoisebiologicalsafetycabinetintheworld.

EscolauncheseSafe,thetechnologicallyandergonomicallyadvancedTÜV-NORDcertifiedBSC.

EscolaunchesSubliMate®BenchTopFreezeDryers.

EscolaunchesCelCulture®CO2incubatorwithSuppressedO2feature.

EscolaunchesLabculture®InVitroFertilizationWorkstations.

2007

Infinity®–theworld’sfirstbiologicalsafetycabinetdesignedwitharedundantdualfansystemthat

guaranteesoperatorprotectionevenincaseofasinglefanfailure.

EscolaunchesVIVAAnimalContainmentWorkstations.

2008Isoclean®-newcompoundingpharmacyisolators.

FrontierAcela®-theworld'sfirstergonomicallydesigned,angledfront,

highperformancelowflowfumehood.

Labculture®ClassII(LowNoiseSeries)–introducedastheindustry'slowest

noise(~50dBAperEN)biologicalsafetycabinet.

Escoearnson-siteULaccreditation.

2005

2006

EscoearnsfirstNSF/ANSIcertificationforbiologicalsafetycabinet.

EscolaunchesitsfirstlineofDuctlessFumeHoods.

EscoPharmaequipmentwaslaunchedatPMECChinaexhibition.

EscobecamememberofNSFJointCommitteeandJACACommittee.

5

Global Network

Products and Application

Sample Preparation

•ClassIITypeA2BiologicalSafetyCabinets

•ClassIITypeB2BiologicalSafetyCabinets

•ClassIIIBiologicalSafetyCabinets

•HorizontalLaminarFlowCleanBenches

•LaboratoryAnimalResearchWorkstations

•VerticalLaminarFlowCleanBenches

•PCRCabinets

•FreezeDryers

Esco Life Science Tools

Software

General Equipment

Life Science

Sales/ServiceSubsidiaryCompanies

Distributors

R&DCenters

Factories

RegionalDistributionCenters

•LaboratoryOvens

•LaboratoryIncubators

•RefrigeratedIncubators

•MicroplateShakers

•DuctlessFumeHoods

•LaboratoryFumeHoods

•ExhaustBlowers

•FumeHoods

•FumeHoodAirflow Monitors

Pharmaceutical Equipment

Assisted Reproductive Technology

(ART)

Chemical Research

•AsepticCytotoxicIsolators (ACTI)

•Containment

•PowderWeighing

•Cleanroom

•IVFWorkstations

•Multi-roomIncubators

Sample Cultivation

•CO2 Incubators

•CO2 Incubators with Copper Interior Chamber

•CO2 Incubators with UV Lamp

•CO2 Incubators with Suppressed O2

Sample Analysis

•Conventional Thermal Cyclers

•Real-time PCR Systems

Sample Storage

•Upright Ultra-low Temperature Freezers

•Laboratory Refrigerators and Freezers

•Voyager

Esco Product Guide

AnintegralpartofourbusinessplanningeffortisbasedonmanagingarobustresearchanddevelopmentprograminSingapore,China,EuropeandtheUSA,balancedagainstaninvestmentinservicesupport,trainingandcustomereducation. Compared to industryaverages,Esco investsa significantpercentage of annual revenues inresearchanddevelopment.Asaresultofourinvestment,andwithcontinuous

feedbackandideaevaluationamongourresearch,globalsales,marketing,purchasing and manufactur ingteams;Escoproductsreflectthebestcontemporarydesignsinperformance,ergonomicsandcustomersatisfaction.

• 70engineerslocatedintechnologycentersinSingapore,China,EuropeandtheUSA

•Growingpatentportfolio

•Corecompetencies:

- Embedded system, sensor andsoftware development andintegration

- Containment engineering forbiohazards,chemicalvaporsandhazardouspowders

- Temperature,humidity,gasand environmentalcontrol

- Computationalfluiddynamics

- Andmanymore

Continuous Research and Development

Product Development and Innovation

Esco'smanufacturingadvantagestemsfromourextensivedegreeofverticalintegration,enabledbyourworld-leadingthroughput.Allprocesses,withafewexceptions,areperformedin-house.Thisallowsustoachievequalityandreliabilitythatistrulyworld-class.Ourplantcapabilitiesinclude:• Incomingmaterialsinspectionandwarehousing

•CNC-contro l led sheet meta lfabricationandwelding

• Environmentally-friendly powdercoatinglines

• Electromechanical final productassembly

• Electrical/electronicssub-assembly•Multi-stepelectrical andphysicalperformancetesting

• Independentqualitycontrolateachstepintheproductioncycle

•Microbiology,chemistry,containmenttestlabs

Esco'sfocusonqualityandtimelinessisrelentless.Continuousimprovementisamantra.CrossfunctionalteamsfromEscoProduction,R&D,QualityAssurance,SeniorManagement,areregularly assembled to review andimplementareasforimprovement.

Quality,Cost,Productivity,Effectiveness,Timeliness

Manufacturing6

7

Life Science

Esco Biological Safety Cabinets represent more than 20 locally, regionally and internationally-recognized certifications. These accreditations testify to the enhanced performance of Esco products in biological and microbiological applications.Introduction: Escoisaworldleaderinbiologicalsafetycabinets,offeringthe industry'swidest product range,with thousandsofinstallationsinleadinglaboratoriesinmorethan100countriesaroundtheglobe.Esco'sbiologicalsafetycabinetshaveearnedmore independentcertifications, inmorecountries, inmore languages,thananyotherproduct,demonstratingourcommitmenttotheindustry'sbestsafetyandquality.

Features: • EnergysavingECMblower.*• ISOCIDEantimicrobialpowdercoating.• ULPAFilterwith>99.999%efficiency@0.1–0.3µm.• Largeperformanceenvelope.• Ergonomicdesign.• Lownoise.• Easytoclean.

Product Lines:•ClassII,TypeA2BiologicalSafetyCabinets.•ClassII,TypeB2BiologicalSafetyCabinets.• ClassIIIBiologicalSafetyCabinets.• FormalinVaporizers.•OptionsandAccessories.

*Most Models

The World's Most Certified CabinetsBiological Safety Cabinets

• NSF/ANSI49

• UL61010

• JISK3800

• SFDAYY-0589

• EN12469

• SANS12469

Certifications:

Sample Preparation

PublicHealthofEngland

Esco Product Guide

8

Life Science

Introduction: Escoisanindustryleaderinthedevelopmentofprofessionalqualitylaminarflowcleanbenches.Withtensofthousandssoldthroughoutthelifesciencesmarketworldwide,Escohasreinforceditsreputationfordependabilitybyprovidingreliableprotectionforsamplesandworkprocesses inamultitudeofapplications.

OurselectionofVertical,HorizontalandSpecialtycleanbenchesoffersavarietyofchoicesforinstallationswherehighqualityconstructionisessential.OurcleanbenchesareaerodynamicallyengineeredanduseonlypremiumqualityULPAfilterswithintegratedmotor/blowerassembliesforquietoperationandlongservicelife.

Since1978,Escohasemergedastheindustryleaderproducinglaminarflowcabinetsthatarethepremiumselectionforthediscerningresearcherandofferingacombinationofvalue,highqualityconstruction,lowoperatingnoiselevels,andawideproductrangetosuitallbudgets.

Esco is the world leader in premium laminar flow cabinets for the global life sciences market.

The Leading Solution for Research LaboratoriesLaminar Flow Clean Benches

Sample Preparation

VerticalLaminarFlowCabinet

• Airdoesnotblowstraighttouser’sface.

• Aircurtainisnotdisruptedbylargeobject.

HorizontalLaminarFlowCabinet

• Easiertoputsensitivematerialnearcleanairsource.

• Contaminant is not blowntowardssensitivematerial.

9

Life Science

EscoSolutionforAnimalResearchLaboratoriesLab Animal Research Products

Animal research, cage changing and bedding disposal procedures are now simpler,

safer and more productive with the Esco range of VIVA® Lab Animal Research Products.

Introduction: Esco’sexperienceincleanairandcontainmenttechnologiesextendstolabanimalresearchproductstohelpprotectthe investigator, animal technicians, animals, and theenvironmentduringresearch,cagechangingandbeddingdisposalprocedures.

VIVAlabanimalresearchproductshelplaboratoriescomplywithNIOSHrecommendationstocreateasafer,healthier,moreproductiveworkenvironmentandtoensurethatthisisachieved,operatorandenvironmentprotectionofeachVIVAworkstationwasevaluatedthroughtheELISAanalysis.

Actualcagechangingandbeddingdisposaloperationswereperformedtosimulatehowtheworkstationsareused,andallergenconcentrationatdesignatedareaswassampled.TheallergenconcentrationwasquantifiedusingsandwichELISAmethod.

Theresult:VIVAWorkstationsofferhighlevelsofoperatorandenvironmentprotectionthatcansubstantiallyhelptominimizeallergenexposure.

Product Lines:•UniversalAccessAnimalContainmentWorkstations.• DualAccessAnimalContainmentWorkstations.• BeddingDisposalAnimalContainmentWorkstations.• AirShowers.

Sample Preparation

Esco Product Guide

10

Life Science

Sample Preparation Equipment

PCR Cabinets

Introduction: PolymeraseChainReaction* (PCR) isaprocesswheremillionsofcopiesofDNAareamplifiedfromasinglecopyorlowcopynumbertemplate.BecauseofthehighcopynumbergeneratedduringPCR,itisalsoessentialtopreventpossiblecontaminationofthePCRsamples.

ContaminationcontrolandPCRprocessrepeatabilityissimplifiedwiththeEscorangeofPCRCabinets.EachEscoPCRCabinetprovidesULPA-filteredverticallaminarflowtopurgetheworkareaofcontaminantsbetweenamplificationsandduringpreparatoryprocedures.AnintegratedUVlampenablesrapiddecontaminationoftheworkzonebetweenexperimentsandpreventscross-contamination.Escoofferspremiumperformanceforapricethatiscompetitivewithconventional"dead"airboxes.

Features:•Greater protection against contamination from theambientenvironmentandcross-contaminationwithinthemainchamber.

• Highqualitypolyesterpre-filterandmainHEPAfilterwithatypicalefficiencyof>99.99%at0.3microns.

• Built-inUVlampwithtimertofacilitatedecontaminationbetweenPCRcycles.

• Availablein0.6,0.9and1.2metermodels(2’,3'and4').

Freeze Dryers

Introduction: Esco,aworldleaderincleanairequipmentandrefrigerationcontrolareproudtoannouncethelaunchofanewrangeof“stateoftheart”BenchTopFreezeDryers.Designedtomeettherequirementsofmodernresearch.

Features:• 3modelsareavailablewithcompactdesign,andcanachievelowcondensertemperaturedownto-90C.

• 2Kgand5Kgicecapacityallowingformultiplecyclesbeforedefrosting.

• LusterClear™fullyflushedandcleancondensersurfacedesignallowingforeasycleaningandpreventingdamagetocoolingcoilsduringicecoreremoval.

• SmarTouch™ large touch screen controller deliversergonomic, intuitive interfaces and easy-to-useprograming for freezedrying,defrosting, languageselection,pressure,temperatureunits,dataloggingfilesandrealtimeclock.

• ANewinnovativeEzySeal™rubbervalvedesignforeasierflaskfitting,sealing,dryingandremoval.

• PressuresensorandIceOut™defrostsystemareequippedasstandardforthediscerningresearchers.

Microplate Shakers

Introduction:TheEscoProvocellShakingMicroIncubatorisdesignedforawidevarietyofmixingapplicationsforaccurateincubationofreactionsanddenaturationofnucleicacidsandproteins.Provocellcombinesanadvancedmicroprocessor-basedcontrollerwith Peltier heating and cooling to deliver

outstandingreliability,safetyandoverallperformance.

Sample Preparation

DesignedandMadeintheE.U.

11

Life Science

Sleek, reliable and intuitive, Esco CelCulture CO2 incubators provide comprehensive

sample protection that brings your scientific dreams one step closer to reality.

Introduction: EscoCelCulture-worldclassCO2IncubatorfromEscowiththebesttemperatureandCO2controlprovidingsuperiorprotectionandthebestenvironmentforcellcultures.

Features:•Precise Parameter Control:-bestuniformityandcontrolamongcompetition,whichmeanssamplesareevenlyheated.

-fastrecoverywithoutovershoottoensureuniformCO2levelsevenwithfrequentdooropening.

-directheatandairjacketforrapidtemperaturerecoveryand provide isolation from ambient temperaturefluctuations.

- forced convection systemaccelerates recovery ofchamberairafterdoorclosingtopreventcontamination.

•Robust Contamination Control for optimum protection of your samples using:-ULPAfilter-validated90ºCmoistheatdecontamination-filteredgasinjectionlines-IsocideTMantimicrobialcoating

•Toprovidemaximum safeguardingof your cellcultures, all CelCulture® CO2 incubators can be used with Voyager Software:-allowsautomatic,continuousmonitoringofdeviceparameters.

-withalarmstoalertuserwhenexceedingpre-defineparameterlimits.

-allowsusertoconfiguredevicesremotely.•User friendly controller software interface:-Comprehensive,user-configurablealarms.-CelAlert™alarmsystemremindsusertoreplaceparts.-Intelligentdataandeventloggerrecordsallincubatorparametersforonscreenrecall.A16Mbbuilt-inflashmemoryguaranteeslongtermstorageofdata.

Certifications:•HPA(MoistHeatDecontamination)

• ULListed

•MEA(MouseEmbryoAssay)

Cradle for Beautiful CellsCO2 Incubators

Sample Cultivation

Esco Product Guide

12

Life Science

PCR Thermal Cyclers

Esco PCR products are used in genomics, proteomics, molecular biology and forensic sciences where DNA amplification is required.

Conventional Thermal Cyclers

Introduction: PolymeraseChainReaction(PCR)isfundamentaltoalmostallapplicationsrequiringahighcopynumberofgeneticmaterialanditisusedinalllaboratoriesworkingwithDNAandRNA.

EscooffersachoiceofConventionalThermalCyclermodelsdesignedtomeetcriticalrequirementsforalmostallkindsofPCRvariantssuchasGradientPCR,TouchdownPCR,High-throughputPCR,InsituPCR,andsoon.BlockconfigurationsareavailableforanumberofsampleformatsofPCRtubes,strips,platesandslides.

ChoosetheSwiftMiniProorthenewAerismodelforreliableconventionalthermalcycling.

Features:•Excellenttemperatureuniformityandstability.• Suitableforvarioussampleformats,whichcansimplifyexperiments.

•Userfriendlycontrolsandoperation.•Longwarrantyperiodwipesyourworriesaway.

Real-time PCR Systems

Introduction:Overthe last5years,EscoThermalCyclershavebeenknownundertheSwiftbrandthatalsoincludesRealTime(Quantitative)PCRsystemsundertheSpectrumproductline.

TheEscoSwiftSpectrumqPCRmachinescomein48-and96-wellformatsandhavefullfunctionality.Notably,theseareopensystemsdesignedforusewithmostcommonlyavailabledyesthataresuitabletoapplicationssuchasdiagnostics,research,andquarantineproducttesting.Theincludedsoftwareisverypowerfulandseamlesslyperformsabsoluteorrelativequantification,andevenSNPanalysis.

ChoosetheSwiftSpectrumRealTimeThermalCyclersforDNAquantificationatyourfingertips.

Features:• Best uniformity and accuracy ensure reliability andexcellentperformance.

•Open systemwithwide selectionof excitation andemissionwavelengthoptions.

• User-friendlywith three language choices (English,ChineseandSpanish)onthecontrolsystem.

• Industry-leadingwarrantyforpeaceofmind.

Sample Analysis

13

Life Science

Incorporates the best and most complete sample protection and sample organization system of any ULT manufacturer

Highest Reliability, Top PerformanceUltra-low Temperature Freezers

Introduction: Ultra-lowtemperature(ULT)freezersarewidelyusedinscientificresearchforlong-termstorageofsamples.AsULTfreezersareoftenoperatedat-80°Ccontinuouslyforyears,reliabilityisofparamountimportancetoresearchers.

Escohasusedindustry-acceptedHighlyAcceleratedLifeTesting(HALT)tostresstesta largenumberofLexiconFreezersatextremeconditions.AllLexiconfreezerspassedtheseextremestresstestsinsuringadesignthatisoptimizedtoprotectyourprecioussamples.

InaccordancewithANSI/ASHRAE72-2005andARI1200-2006/2008guidelinesandastestedbyaULvalidatedthirdparty test lab,DNSUSA,theEscoLexiconULTFreezersurpassedtheperformanceof5majorcompetitorswithlowerenergyconsumption,superiorcabinetperformance(asmeasuredbywarm-uptime),anddemonstratedalargerBTUrefrigerationreservecapacitytoinsurethehighestlevelofperformanceandprotectionofyoursamples.

Features:• ExcellentVialCapacityWithAMinimalFootprint.• ThreeControllersAreAvailableInEverySizetoMeetEveryCustomerNeeds.

• CompleteEventMonitoringandLoggingSystem.• EmailAlertsViaWi-FiandNetworkCableinCaseofSampleThreateningAlarms.

• UniquePredictiveFailureManagementandFreezerHealthMonitoringSystem.

• BatteryBack-Upto72HoursandAvailableCO2andLN2

BackupSystems.• CompatiblewithVoyagerSoftwarethatAllowseasy,unifiedlocalfreezercontrolandmonitoringforproperoperationfromacentrallocationviauserestablishedorlocalnetwork.

• SampleTrackerInventoryManagementSystemtoTrackallStoredSamples.(PatentPending).

• iRMAPallowsforanadditionaloptionalEscoservicetoallowEscotomonitorfreezersfromaremotelocation.

• PROtectRedunduntWirelessSampleMonitoringSystem.

Certifications:•ULListed

Sample Storage

DesignedintheUSA

Esco Product Guide

14

Life ScienceSample Storage

High Performance SeriesLaboratory Refrigerators and Freezers

Introduction: EscoHPSeriesLaboratoryRefrigeratorsandFreezersarehighperformancemodelsdesignedtoprovideahighlevelofprotectiontosamplesusedinlifescienceresearchandclinicalapplications.Whenthehighestlevelofcoldstorageperformance,reliability,andflexibilityisneeded,theEscoHPseriesofLaboratoryRefrigeratorsandFreezersisthebestchoice.AllproductshavetheCEmarkasademonstrationofquality.

Features:•Robust and functional construction:-Exteriorofallmodelshaveananti-bacterialcoatingtominimizecontamination.

-Allmodelsincludeastainlesssteelinteriorthatprotectsthecabinetfromrustandcorrosivereagents.

- Insulating and anti-mist tempered glass door onrefrigeratorsoffersexcellentvisibilityandmaintainssuperiorthermalperformance.

-Doorautomaticallycloseswhenreleasedtomaintaintemperatureandtoprotectsamples.

-Allunitsincludeakeylockforaddedsamplesecurity,shelves,mountedonanti-tiltclipsandlockingwheelsorcastersforeasymovement.

• Safety features:-Opendooralarm.-Hightemperaturealarm.-Lowtemperaturealarm.-Powerfailurealarm.-Condenserfilteralarm.-Drycontacttoconnecttoremotealarms.

•Environment-Friendly:- Standard internal LED lighting saves 70%energycomparedtoordinary lightingandhasavery long

lifetime.-Allunitsfeaturelowenergyconsumption.Savesmoney!-Useofecofriendlyrefrigerants-Recyclableandeco-friendlymaterials.

-CFCfree-Verylownoiselevel.

•Advanced electronic control system:-Electroniccontrollerwith0.1°Cresolution.Bestintheindustry!

- Automatic defrost eliminates ice in almost allenvironments.

-Controlsareavailablein5languages.-Controllercanincorporatepasswordprotectionforgreatersecurity.

-Theinteractivedisplaymaybecustomized.•Easytocleanandservice:-Stainlesssteelchamberresistscorrosionandiseasilycleaned.

-Automaticdefrost.-Servicecanbecarriedoutfromthetop/front.-Diagnostic functions inthemicroprocessor includehistoricalread-outoftheparameters.

-Lowservicecosts.•Optional accessories:-Additionalshelvesandaluminumdrawersareavailable.Thedrawersarelightweight,chemicalresistant,andaresuppliedwithpartitions.

Product Line:• HPseriesRefrigerator:140liter,400liter,700liter,1500liter.• HP seriesFreezer (-25°C):140liter,400liter,700liter,1500liter,HPseriesFreezer(-40°C):400liter,700liter.

• HPseriescombinedRefrigeratorandFreezer:400liter,700liter.

Software

15

Remote Monitoring, Datalogging, Programming SoftwareVoyager

•Ability to generate reports and graph ofdifferentdeviceparameters.

•Abilitytosaveandreportlogdatainvariousformats.

• Easy PC interfaceusingUSB, LAN cablesorviaWi-Fi.

•Protectthesamplesbyprovidingalarmswhenexceedingauser-definedparameterlimitviaautomaticemailalerts.

•AllowsallEscothermostaticproductstobeconnectedandmonitoredforproperoperationfromacentrallocation.

Compatible Esco Equipment (Clockwise from top):

LexiconUltra-lowTemperatureFreezer(UUS)

IsothermRefrigeratedIncubator(IFC)

IsothermForcedConvectionIncubator(IFA)

CelCultureCO2Incubator(CCL)

Introduction: EscoVoyager® isaPC-basedsoftwarepackage developed for the remotemon i t o r i n g , d a t a l o gg i n g , a n dprogramming/deviceconfigurationofEscocontrolledenvironmentlaboratoryequipment. Compatible equipmentincludeslaboratoryovens,microbiologyincubators,CO2incubatorandultra-lowtemperaturefreezer.Voyager®interfaceswith individual Esco equipment overRS485usingtheEscoBUScommunicationsprotocol.

Esco Product Guide

16

Chemical Research

TheSafe,EnergyEfficientSolutionforModernChemistryDuctless Fume Hoods

Esco Ascent Ductless Fume Hoods provide protection to both

laboratory personnel and the environment from toxic fumes.

Introduction: EscoAscentDuctlessfumehoodsareasensiblebalanceofquality,performanceandcost-effectiveness.Theyprovideprotectiontobothlaboratorypersonnelandtheenvironmentfromtoxicfumes.Unlikeconventionalfumehoods,thesehoodsfilteroutchemicalfumesandrecycleairdirectlybacktothelaboratory,providingenergysavings,personnelandenvironmentalprotection,mobility,andconvenienceasyoudonothavetodealwithcomplicatedductingsystems.

EscoDuctlessfumehoods’fumecontainmentandairflowuniformitymeettherequirementsofASHRAE110-1995,BS7258,EN14175-3andAFNORNFX15-203.

Key Benefits:•Lowcost:-Noductworkrequired.-Noexhaustsystemrequired.-Savestheneedforelaboratemake-upairsystems,inturnsavingrunningcostsrequiredtoconditionmake-upair.

•Convenience:-Minimalinstallationexpense.-Mobile,flexibleandcanbeeasilyrelocated.

•Environmentallyfriendly:-PersonnelandenvironmentalprotectionwiththeuseofNanocarb™carbonfilters.

-Savesenergyasthereisnoneedforcomplicatedductingandmake-upairsystems.

Product Lines:•TheStandardAscentMaxDuctlessFume.•TheAscentMaxDuctlessFumeHoodwithsecondarybackupcarbonexhaustfilter.

•TheAscentMaxDuctlessFumeHoodwithtransparentglassbackwall.

•TheAscentMaxDuctlessFumeHoodwithsecondarybackupHEPAfilter.

Ascent Max Ductless Fume Hood Powder Max Powder Weighing Enclosure

Ascent Opti Ductless Fume Hood

Ductless Fume Hoods

17

Chemical Research

Laboratory Fume Hoods

Laboratory fume hoods serve to control exposure to toxic, offensive or flammable vapors, gases and aerosols.

Frontier Duo Fume Hood

Laminar Topography and Perfect Protection PerimeterLaboratory Fume Hoods

Introduction: EscoLaboratoryFumeHoodsareamongthebestintheworld,compliantwithinternationalstandardssuchastheAmericanASHRAE110-1995andtheBritishBS7258,independentlytestedbyINVENT-UK.TheyhavealsobeensuccessfullytestedforfumecontainmentspecifiedintheEuropeanStandardEN14175-3andreceivedUnderwritersLaboratories,USAClassificationunder thefumehoodstandardUL1805,testedforfire,electrical,andmechanicalhazards.

Features:•Durableconstructionmadeofindustrial-gradeelectro-galvanizedsteelwithcorrosionandabrasionresistant,oven-baked,powder-coatedfinish.

• Precisely tuned aerodynamic design eliminates airturbulence,minimizesnoiselevelsandstaticpressurelosses.

•Constantvolume/highperformanceconcepteliminatestheneedforcomplexVAVsystems.

•Designedwithcomputationalfluiddynamicsensuringmaximumcontainment,thereforeenhancingsafety.

• Ergonomically designed for operator comfort andconvenience.

• Isocide antimicrobial coating prevents surfacecontaminationandinhibitsbacterialgrowth.

•ASHRAE110andEN14175certifiedandULclassified.

Product Lines:•GeneralPurposeBenchtopHoods.•AcidDigestionHoods.• PerchloricAcidHoods.•RadioisotopeHoods.• FloorMountedHoods.•HighPerformance,LowFlowHoods.• PolypropyleneHoods.• ChemicalFumeScrubbers.• ExhaustBlowers.

Certifications:•ASHRAE110

•EN14175

•ULclassified

Frontier Floor MountedFume Hood

Frontier Acid DigestionFume Hood

Frontier RadioisotopeFume Hood

Esco Product Guide

18

Chemical Research

Fume Hoods Accessories

Fume Scrubbers

Introduction: Aproperly used andproperly functioning fumehoodexhaustshazardousgases,dusts,mists,andvaporsfroma confined location and helps protect workers frominhalationexposure.Tobeabletoprovidethebestfumeexhaustsystem,Escooffersfumehoodsaccessoriessuchasfumescrubbers,exhaustblowers,andairflowmonitorscompatiblewithmostEscofumehoods.

Esco'sFumeScrubberprovidesexcellentairpollutioncontrolforwatersolublechemicalspresentinthelaboratoryfumehoodexhaustfumes.Moreandmorelaboratorydesignersandfacilityoperatorsareconsideringtheuseofscrubbersfortheirfumehoodstoaddresslaboratoryoperatorsafetyandenvironmentalconcerns.

Key Benefits:•Excellentremovalefficiencieswith95-98%efficiencyformostwater-solubleacidandbaseladenairstreams.

•Durablebodymadeofchemicalandcorrosionresistantpolypropylene.

•Thepacking,spraymanifoldandmisteliminatorcounted

ontopoffumehood,pumpandreservoirinthebasecabinet.Thisarrangementensuresthatminimalextraspaceisrequiredforthescrubbersystem.

Exhaust Blowers

Introduction: TheEscoExhaustBlowerisspecificallydesignedforcorrosivefumehoodapplications.

Key Benefits:•Plasticimpellerandcasingthatarehighlyresistanttochemicalsandcorrosion.

•PerformanceinaccordancewithAMCA210-85andISO5801.

• Single block, strong, high density, UV-treated andrecyclablepolypropylene(PPH),noweldedjoints.

Fume Hood Airflow Monitors

Introduction: Esco®SentinelXL™FumeHoodMonitormeasuresandmonitorsthe"facevelocity"insideafumehood.Thesystemwillgenerateanalarmifthefacevelocitydropslowerthanthelowalarmpointorriseshigherthanthehighalarmpoint.

Allofthefeaturesinthismonitorsystemwillprovidetheuserwithahigherlevelofconfidenceinhisorhersafetywhenusingthefumehood.

Assisted Reproductive Technology(ART)

19

The Esco suite of ART equipment is the best choice for proven safety and performance

for the fertility laboratory.

EscoAssistedReproductiveTechnology(ART)EquipmentART Workstations

Introduction: TheFertilisafeMulti-Zone (MZ)ARTWorkstation isanadvancedworkstation specially designed forAssistedReproduction Techniques (ART) such as gamete orembryomanipulationduringIVF.Aprecision-controlledheatedtabletopprovidestheusertotalcontrolovertheenvironmental conditions required for embryologicalprocedures.

TheFertilisafeMZhasother features thatmake it theperfectsystemforfertilitylabs.Itincludesahumidificationsystem,provisionforstereomicroscopes,integratedlightsource,andheatedglassstage.WhatmakestheFertilisafeuniquehoweveristhesurveillancesystemprovidedontheintegratedtouchscreenmonitor.Thesurveillancesystemprovidesgraphicalinformationofthe10heatedzones(4ftwidthmodel)or20heatedzones(6ftwidthmodelwithdualmicroscopesetup).

Key Benefits:• Next-generation temperature regulation for ARTapplications.

• Real-time feedback of workstation performanceparametersviathesurveillancesystem.

•Lownoiseandvibration.

Features:•Advancedsmartpowerinjectionmulti-Zoneheatedtableplate(9+1zones)keepssampleswarm.

• Surveillance system running data logger (included)constantly displays important parameters such astemperatureofeachzoneandhumidifiedgasflowrate.

•Atouchscreenmonitorisbuilt-inandrunsthesystemsoftware.

•Provisionforintegrationofmostcommonmicroscopescomesstandard.

•Integratedheatedglassstageandintegratedtransmittedlightsourcewithdual-sidedmirrorandintensitycontrolknobscompletethesystemformicroscopywork.

• PT1000 temperature validation ports allow easytemperaturevalidation.

•Thehumidificationsystemprovidesdigitalflowcontrolofpre-mixedgas thatkeepssamples inacontrolledenvironmenteliminatingdeadairzones,prolongingmainfilterlifeandenhancingproductandcross-contaminationprotection.

DesignedinDenmark

Assisted Reproductive Technology(ART)

Esco Product Guide

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Multi-room Incubators

Designed for the fertility laboratory, the new Esco Miri delivers features that not only

make sense, but deliver top performance making it the perfect choice for routine

incubation of embryos during IVF.Introduction: TheEscoMiri isarevolution informandfunctionalityforCO2incubatorsforinvitrofertilization(IVF).With6chambers,theMiriisamulti-roomincubatorthatallowsusers toaccess theircultures inonechamberwithoutaffectingtheneighboringchambers.Thus,theharmfuleffectsoffluctuationsintemperatureandgascausedbyfrequentincubatoraccessareavoided.

BuiltspecificallytoequipIVFlaboratoriesandclinicstoprovidethebeststandardsofcare,itboastsauniquesetoffeaturesthatcannotbefoundelsewhere.

Features: •6chambersarecompletelyindependentfromeachotherpreventingcross-contamination.•MixedgasNOTrequired=reducedoperatingcosts.•Heatinginthelid(oiloverlaynotrequired).preventscondensationandenhancestemperatureregulation/recovery.•DocumentedUVCdecontaminationofrecirculatedgas.•MEAtestedanddocumented.

•12xPIDregulationsystem,themostadvancedintheworld.

•Built-intemperaturevalidation.•Fullparameterdisplayatadistance.•Pressuresensorsonexternalgas.

Certifications:•IEC/EN60601-13rdedition

•EUMDDClassIIaMedicalDevice

DesignedinDenmark

MadeintheE.U.

Pharmaceutical Equipment

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Pharmaceutical Equipment

For decades, Esco has been a pioneer in the development of clean air / containment

technology, earning a reputation for innovation in the worldwide laboratory and

cleanroom industry. Esco utilizes this wealth of knowledge and experience to expand

its cleanroom range into what is now the Pharma Division.

Introduction: OurEscoPharmaDedicatedR&DEngineershaveacombined30yearsofexperienceinsystemsdesignofavarietyofcontainmentandasepticprocessequipment.Thisteamofengineershashelpedtogrowthepharmalineofproductsfrombasiccleanroomequipmenttomorestate-of-the-artproducts,fromhospitalpharmacyisolatorstoadvancedcontainmentisolatorsystems,includingnewproductstomeetvariousneeds.

EscoPharmaceuticalEquipment isdivided into3maincategories:

- AirflowContainment.- IsolationContainment.- CrossContaminationFacilityIntegratedBarriers.

Airflow Containment Products:

•PharmaconDownflowBooths.•EscoStraddleUnitSingle,EscoStraddleUnitDouble,CustomLFCabinets.

•EscoGarmentStorageCabinet,LaminarFlowStorageCabinet.

•LaminarFlowVerticalTrolleys,LaminarFlowHorizontalTrolleys.

•CeilingSuspendedLaminarAirFlows,FanFilterUnits.•LaminarFlowBooths,ModularEnclosures.

Isolation Containment:

•AsepticContainmentIsolator(ACTI).•Weigh/DispenseContainmentIsolator(WDCI).•CAIandCACI.•CustomIsolators.

Cross Contamination Facility Integrated Barriers:

•StaticBarriers.•DynamicAirflowBarriers.•BiodeconBarriers.

DesignedintheUSA

General Equipment

Esco Product Guide

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Introducing Esco Isotherm® - world class laboratory ovens and incubators from Esco with the technologies and compliance to prove it.

Reliable Performance For Universal ApplicationsLaboratory Ovens and Incubators

Introduction:IntroducingEscoIsotherm®-worldclasslaboratoryovensfromEscowiththetechnologiesandcompliancetoproveit. Ergonomic, intuitive interfaces,microprocessorPIDcontrolswithprogrammingoptions,4-zoneheatedairjacket,preciselytunedandtestedventilationandinsulationpackage,allsupportedbyEsco’ssolutions-basedsalesandservicerepresentativesworldwide.

Features:•SolarisTMPre-HeatChamberTechnology.•Forcedconvectiondesignproducesfastertemperatureresponse rates, improved uniformity, and reducedfluctuation.

•Fanspeedandairexchangeratesareadjustable.•WideRangeofProgrammingOptions.

•Multipleredundantover-temperatureprotectionsystemstoguaranteemaximumsampleanduserprotection.

•AccessportforTemperaturevalidationandmapping.•ErgonomicDoorHandlewithKeylock.

Product Lines:• ForcedConvectionLaboratoryOvens.• ForcedConvectionLaboratoryIncubators.• RefrigeratedIncubators.• StainlessSteelOptionsforallsizesofOvens,Incubators&LowTemperatureIncubators.

EscoAfterSalesServices

After Sales Services

Parts Availability

Wheneverserviceisneededandpartsarerequired,minimizingdowntimeisacriticalobjective.StatisticalusageanalysishelpsEscopredictpartslife,permittingEscotomanagelogisticsandstageproperinventoriesaroundtheworld.Thecombinationofpredictivemaintenance,historicaldataandgeospecificproximityassuresourcustomersthatpartsand

laborareavailablewheneverserviceisscheduledthroughthelocalsalesorganization.

Registration, Documentation and Instruction

QualitycontrolatEscoextendsfromresearchanddevelopmentthroughengineering,manufacturing,shipment,deliveryandcustomerfeedback.Escomaintainsanaggressiveprogramtoencouragewarrantycardregistrationbymail,emailoronlinesubmittalsothatweknowwhereEscoproductsarelocatedandhowtheyarebeingused.DatafromourwarrantyregistrationprogramisconfidentialandprovidesuswithvaluablecontactinformationshouldweeverneedtonotifyyouaboutyourEscoproduct.

AllEscoproductsincludeuniqueserialnumbersforidentification.

Documentationforallperformancetests isarchivedandmaintainedforcustomerreference.

Online Technical Information

Sitepreparationinstructionsareusefulbeforeproductarrivalandinstallation.Installationandstart-upmanuals,operationmanualsandquickreferenceguidesareavailableanytimefromtheEscoresourcesonline.AninteractiveonlineLiveSupport™conciergecenteraccessiblethroughtheEscowebsiteoffersextendedhoursofoperation.LiveSupportpermitsuserstodialoguedirectly

withEscopersonnel.

References and Links

FormoreaboutEscoproducts,markets,employmentopportunities,history,education,informationresources,andSingapore,visitourinformationportal

atwww.escoglobal.com.

LIVE SUPPORTescoglobal.com

LIVE SUPPORTescoglobal.com

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EscoTechnologies,Inc.•2940TurnpikeDrive,Units15-16•Hatboro,PA19040,USAToll-FreeUSAandCanada877-479-3726•Tel215-441-9661•Fax215-441-9660us.escoglobal.com•usa@escoglobal.com

EscoMicroPte.Ltd.•21ChangiSouthStreet1•Singapore486777Tel+6565420833•Fax+6565426920•mail@escoglobal.comwww.escoglobal.com

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