GPAT MODEL TEST-3

Question 1 of 100Qualitative analysis by the polarography is based on

  a) Electrode potentialb) Half wave potentialc) Migration Currentd) Limiting current

Question 2 of 100DLVO theory is related to

  a) Stability of emulsion  c) stability of colloids  e) Stability of suspension none

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Question 3 of 100Nux vomica contains strychnine not less than

A) 2.3B) 2.1C) 1.2D) 3.2

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Question 4 of 100In coriander sativum; primary ridges are

A) 8 in numbers, prominent & straightB) 8 in numbers, wavy & inconspicuousC) 10 in numbers, wavy & inconspicuousD) 10 in numbers, prominent & straight

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Question 5 of 100Monsanto tester is used to test …….of the tablets.

A) FriabilityB) HardnessC) active contentD) disintegration

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Question 6 of 10017, 21-Dihydroxy pregn-4-ene-3,11,20-trione is

A) CortisoneB) CholesterolC) ProgesteroneD) Aldosterone

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Question 7 of 100Which is not characteristic of Gentian roots

A) Stone cells are absentsB) Starch grains are absentsC) Phloem fibers are

absentD) Calcium oxlate crystals are absent

Question 8 of 100A widely accepted detector electrode for pH measurement is

A) Platinum wireB) Glass electrodeC) Ag-AgCl electrodeD) Lanthanum Florid electrode

‘Question 9 of 1001-oxopenam structure and has no 6-acylamino side chain of penicillin is

A) Clavulanic acidB) ImpenamC) SulbactumD) Carbpenam

Question 10 of 100Microorganism used for obtaining dextran by fermentation is

A) Aspergillus oryzaeB) Aspergillus nigerC) Leuconostoc mesenteroidsD) Trichodermal reesii

Question 11 of 100Proenkephaline A is precursor of which one endogenous peptide

A) Leu-enkephalineB) DynorphineC) NeonorphineD) Beta-endorphine

Question 12 of 100Which is the functional group transferred by coenzyme pyridoxal phosphate

  A)amino

 B)acyl

  C)aldehyde D)H-atom

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Question 13 of 100Calcipotriene, a synthetic VitaminD3 analogue has the following attribute

 A)

Pronounced antirachitic activity

B) Pronounced antiscorbutic activityC) Used as a topical application in the treatment of moderate plaque psoriasis

D) Effect on calcium metabolism is 200 times more than ergocalciferolUndo

Question 14 of 100Shinoda Test is used for

A) TaninB) ProteinsC) FlavonoidsD) Fat

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Question 15 of 100Green bone is used in preparation of which type of gelatin

A) Type AB) Type BC) Both A and BD) None of above

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Question 16 of 100Inadequate spreading of the coating solution before drying is called as

A) BlisteringB) CrackingC) Orange peel effectD) Hazing

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Question 17 of 100Which of the enzyme is not used in citric acid cycle

A) a-ketoglutarate dehydrogenaseB) AconitaseC) Isocitrate dehydrogenaseD) Carbonic anhydrase

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Question 18 of 100…….is called as vibrational spectroscopy

A) IR-spectroscopyB) UV-Visible spectroscopyC) ESRD) NMR

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Question 19 of 100Partial or complete separation of top or bottom crown from tablet is termed as

A) LaminationB) StickingC) MottlingD) Capping

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Question 20 of 100Licence of manufacture for sell or distribution of drugs other than those specified in Schedules C, C1 and X

A) Form 24B) Form 27C) Form 26D) Form 25

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Decrease thickness of mucus and increase muco-ciliary movement are termed as

A) AntitussiveB) MucolyticC) DecongestantD) Expectorant

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Question 22 of 100Carr Price reaction of vitamin A gives

A) Intense greenB) Intense violetC) Intense blueD) Intense red

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Question 23 of 100Polarogram containing electroluminescent substance is obtained by plotting

A) Current vs VolumeB) Current vs PotentialC) Resistance vs TimeD) Potential vs Volume

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Question 24 of 100Phenylethylamine and dicyanoamide (cyanoguanidine) are used to prepare

A) PhenforminB) ChloroguanideC) CycloguanilD) Metformin

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Question 25 of 100"Athletics foot" disease is caused by

A) FungusB) VirusC) PlasmodiumD) Bacteria

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Question 26 of 100A conductivity cell consist of

 A)

Two platinised platinum electrode

B) Platinum calomel electrodeC) Platinum tungsten electrodeD) Glass calomel electrode

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Question 27 of 100Cedar wood oil is used in …….Magnification

A) 100x B)10xC) 4xD) 40x

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Question 28 of 100One pair is incorrect

A) Anisocytic-cruciferous stomataB) Paracytic-rubiaceousC) Anomopcytic- ranunculaceousD) Dicytic- irregular cell stomata

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Question 29 of 100Which microorganism is used in the I.P. assay of Streptomycin?

A) Micrococcus luteusB) Klebsiella peumoniae C)Bacillus cereusD) Staphylococcus epidermidis

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Question 30 of 100In the double helical structure of DNA, A + G = T + C is given by

A) Avery-MacLeod-McCarty experimentB) Hershey-Chase experimentC) Nirenberg and Khorana's codon assignments D)Chargaff's rules

Question 31 of 100HLB range of o/w emulsifier is

A) 8 - 16B) 4 - 6C) 1 - 3D) 7 - 9

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Question 32 of 100Alpha-Glucosidase inhibitor used as oral hypoglycemic agent:

A) Guar gumB) AcarboseC) TroglitazoneD) Glucomannam

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Question 33 of 100In normal healthy adult, blood urea concentration is

A) 20 mg/dLB) 80 mg/dLC) 100 mg/dLD) 60 mg/dL

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Question 34 of 100Immobilization of enzyme on self assembling nanocrystalline ceramic core is called

A) mesosomeB) aquasomeC) transfersomeD) neosome

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Question 35 of 100Bancroft rule is used to study the stability of

A) ColloidsB) SuspensionC) solutionD) Emulsion

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Question 36 of 100All enzymes are…….. in nature

A) LipidB) ProteinC) CarbohydratesD) Lipopolysachharide

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Question 37 of 100[2-chloro-11-(1-piperazinyl) dibenzo[b,f][1,4]oxazepine] is known as

A) AmoxapineB) QuetiapineC) DoxepinD) Loxapine

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Question 38 of 100Which of the following is water insoluble polymer?

A) Hydroxypropyl methyl cellulose

B) Polyvinyl pyrolidoneC) Ethyl celluloseD) Hydroxypropyl cellulose

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Question 39 of 100Total number of Purine nucleotides is equal to total number of Pyrimidine nucleotides. This according to

A) Watson & Crick modelB) Bohr's modelC) Chargaff'ruleD) none of these

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Question 40 of 100Saponin glycoside is obtained from one of the followings

A)  Roots of Picorrhyza kuroaB)  Dried roots of Asparagus racemosusC)  Dried leaves of Nerium oleander

 Dried Bark of Rhamnus purshiana

Question 41 of 100One of the following great name is related with magic bullet

A) EhrlichB) Pasteur C)Sorenson  D). Fleming

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Question 42 of 100The most abundant amino-acid present in the body is

A) TyrosineB) GultamineC) AlanineD) Aspargine

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Question 43 of 100Iron content in gelatin should be not more than

A) 20 ppmB) 15 ppmC) 5 ppmD) 10 ppm

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Question 44 of 100which of the following is not 2,4,6- tri-iodo benzoic derivative organ imaging agent

A) diatizoic acidB) Ioxaglate

C) IpodateD) metrizamide

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Question 45 of 100Non protein part of conjugated enzyme is known as

A) ApoenzymeB) HoloenzymeC) Prosthetic groupD) Pseudoenzyme

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Question 46 of 100The extrapyrimidal symptoms are the major side effects of

A) Typical neurolepticsB) Atypical neurolepticsC) Tricyclic antidepressantsD) none

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Question 47 of 100Hydroxylation of cyclopentene with KmnO4 results in

A) cis-1,2-cyclopentanediolB) trans-1,2-cyclopentanediolC) cyclopentanolD) all

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Question 48 of 100Which of the following nucleus present in Hydralazine?

A) NaphthaleneB) PteridineC) AziridineD) Phthalazine

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Question 49 of 100Titrant used in IP assays of fluorouracil is

A) HClO4B) TBAHC) Sodium nitriteD) Iodine

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Question 50 of 100Enteric tablet coating material is

A) Hydroxypropyl methyl celluloseB) PovidoneC) Sodium carboxy methyl cellulose

D) Polyvinyl phthalate acetateQuestion 51 of 100

The first line drug for Burkett's lymphoma is

A) Actinomycine-DB) CyclophosphamideC) VinblastinD) Dauxorubicin

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Question 52 of 100A titration in which potential applied across two electrodes is maintained at a constant value and the current is measured and plotted against volume of titrant is

A) Potentiometric titrationB) Amperometric titrationC) Displacement titrationD) Conductometric titration

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Question 53 of 100Rat holing is problem during manufacturing of tablets is due to

A) Poor design of hoperB) Higher processing temperature or humidityC) Higher granule moisture contentD) Air entrapment

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Question 54 of 100…. Amino acid shows fluorescence

A) TryptophaneB) cysteineC) SerineD) Glycine

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Question 55 of 100Which one of the following is selective a2-antagonist?

A) ClonidineB) IndoramineC) PrazosinD) Yohambine

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Question 56 of 100In differential staining techniques, counter stain used is

A) gentian violetB) crystal violetC) neutral redD) methyl violet

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Question 57 of 100Buck Wheat is rich in

A) FraxinB) RutinC) AesculetinD) Scopoletin

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Question 58 of 100St Johns wort is widely used in United States mainly as

A) AntioxidantB) AntitussiveC) AntidepressantD) none of these

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Question 59 of 100the number of peaks shown by cyclobutane in an NMR spectum is

A) OneB) FourC) FiveD) Two

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Question 60 of 100Canada balsam is used for

A) Fixing the sectionB) Staining the sectionC) Staining the starch grainD) Staining the calcium oxalate crystal

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Question 61 of 100All of the following drugs are thymidine inhibitors except

A) TriflouridineB) CytarbineC) VidarbineD) Idoxuridine

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Question 62 of 100Sodium cromoglycate has been developed from …molecule found in Ammi visnaga

A) TubocuraninB) PhysostigmineC) Khellin

D) MorphineUndo

Question 63 of 100Streptomycin has no useful activity in the treatment of

A) TuberculosisB) BrucellosisC) Bubonic plagueD) Tularemia

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Question 64 of 100Spans are chemically

A) PolysoratesB) Sorbitan estersC) liposomesD) none of these

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Question 65 of 100Which of the following test is not applicable on parentral preparations?

A) Clarity testB) Sterility testC) Uniformity testD) Pyrogen test

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Question 66 of 100A typical auxin of plant, which is found in growing tissue is

A) Indole-3-acetic acidB) GibberlinC) Abscisic acidD) None of these

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Question 67 of 100The plasticizer used in capsule is

A) MannitolB) SorbitolC) PEGD) Lactose

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Question 68 of 100____ color is observed in Murexide test for ______ alkoids

A) Yelow, IndolB) Blue, Imidazole

C) Purple, PurineD) Green, Pyrrole

rythromycin acts by

A) combining with 50s-ribosomeB) combining with 30s-ribosomeC) Interfering with DNA synthesisD) all of these

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Question 70 of 100Tissue plasminogen activator that disperses blood clots, beneficial if it is given within

A) 9 hoursB) 24 hoursC) 3 hoursD) 3 days

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Question 71 of 100Porosity is defined as

A) the ratio of the void volume to the true volumeB) the ratio of the void volume to the bulk volumeC) the ratio of the true volume to the bulk volumeD) none of these

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Question 72 of 100The pinene hydrochloride rearranged into bornyl terpenoid is called as

A) Pinacol rearrangementB) Fries rearrangementC) Beckmann rearrangementD) Wagner-Meerwein rearrangement

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Question 73 of 100The purity and acceptability of the propellant is tested by

A) MoistureB) HalogenC) Non volatile residue determinationD) All of these

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Question 74 of 100Glutamate to GABA is converted by the enzyme

A) KinaseB) Glutamate decarboxylaseC) Maelic dehydrogenaseD) HMG-CoA

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Question 75 of 100The volume (ml) required for a given size of "000" capsule is:

A) 0.75B) 0.25C) 0.95D) 0.55

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Question 76 of 100serum sample of a patient shows elevated levels of (SGOT) Serum-glutamyl-oxaloacetate transferase. The Patient could be suffering from

A) Kidney disorderB) Myocardial infarctionC) Parkinson's diseaseD) Liver disorder

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Question 77 of 100One of the following is not a Leukotriene synthatase inhibitor

A) MontelukastB) ZafirlukastC) ZilutonD) Nedocromil sodium

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Question 78 of 100Find the missing number 24:15::63:?

A) 28B) 56C) 38D) 48

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Question 79 of 100Covering trichomes present in Datura are

A) Uniseriate unicellularB) Biseriate unicellularC) Biseriate multicellularD) Uniseriate multicellular

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Question 80 of 100which drug is used in hypertention that is angiotensin-II antagonist at AT1 receptor?

A) HydralazineB) LisnoprilC) TelmisartanD) Diazoxide

Question 81 of 100

presence of anomocytic stomata on the epidermis of pericarp and mesocarp containing lignified and reticulate parenchyma

A) NutmeghB) CardamomC) CinnamonD) Fennel

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Question 82 of 100Current vs. Potential curve is known as

A) ChromatogramB) PolarogramC) CardiogramD) none of these

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Question 83 of 100In normal HPLC

A) Stationary phase is polar and mobile phase is non polarB) stationary phase is non polar and mobile phase is polarC) both phase are polarD) both phase are non polar

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Question 84 of 100One of the following is largest Cotton producing state in India

A) MaharasthraB) Utter PradeshC) GujaratD) Rajasthan

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Question 85 of 100The most stable conformation of Acetylcholine is

A) TransB) GuacheC) EclipsedD) all of these

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Question 86 of 100The Ex-officio members of pharmacy council of India includes

A) Director general of health servicesB) Director of central drug laboratoryC) Drug controller of IndiaD) All of these

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Question 87 of 100

The mesh size of USP disintegration apparatus is

A) 2 meshB) 5 meshC) 10 meshD) 20 mesh

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Question 88 of 100Non curable disease comes under

A) Schedule- P1B) Schedule- JC) Schedule- ND) Schedule- S

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Question 89 of 100For which of the following BCS, in-vitro in-vivo correlation is not needed?

A) Low solubility, low permeabilityB) High solubility, high permeabilityC) High solubility, low permeabilityD) Low solubility, high permeability

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Question 90 of 100In competitive inhibition of enzymatic reaction, following vent occurs

A) Km increases, Vmax decreasesB) Km unchanged, Vmax increaseC) Km increases, Vmax unchangedD) Km decreases, Vmax increases

Question 91 of 100Isapgol shows color change when treated with ruthenium red

A) VoiletB) YellowC) BrownD) Pink

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Question 92 of 100The unit of measurement for conductance id

A) OhmsB) AmperesC) MhosD) Milli Volt

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Question 93 of 100Compitative nondepolarizing neuromuscular blocking agent is

A) None of Above

B) ParathionC) SuccinylcholineD) Trimethaphan

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Question 94 of 100dipyridodiazepine heterocyclic ring system is present in the following drug

A) efavirenzB) didanosineC) nevirapineD) amithopterine

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Question 95 of 100Column coupling (Switching)HPLC is known as ……

A) Column back flushingB) BoxcarC) FiltrationD) none of these

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Question 96 of 100Exonucleases functions

A) to remove nucleic acid only from the end of chainB) to remove sugar part of DNAC) to break bond within the DNA chainD) all of theses

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Question 97 of 100At critical temperature, the surface tension of liquid

A) increases up to some extendB) does not changeC) becomes zeroD) becomes negative

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Question 98 of 100Psychrometric chart is related to

A) Osmotic pressure

B) solubilityC) HumidityD) evaporation

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Question 99 of 100

In ocular drug delivery system, drug absorption occurs through:

A) CorneaB) ScleraC) ConjunctivaD) All of the above

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Question 100 of 100Which type of sample is used in gas chromatography?

A) Liquid or gasB) SolutionC) Solid, liquid or gasD) Crystal