Global Health Determinants

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    GLOBAL HEALTH AND ITS DETERMINANTS

    Roberto De Vogli

    Department of Epidemiology and Public Health, University

    College London

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    Theory and Evidence

    Ideas

    THEORY

    Inductive Deductive

    Reasoning Reasoning

    EVIDENCE

    Reality

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    Scientific Evidence?

    Data speak by themselves

    vs.

    If you torture the data long enough, they will

    eventually confess everything!

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    Lies, Damn Lies and Statistics

    There are three kinds

    of lies: lies, damned

    lies and statistics

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    It is easy to lie with statistics,

    butit is even easier to lie without them

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    The important thing

    is not to stop

    questioning

    A. Einstein

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    In Africa they didn't know what 'food' meant.

    In Eastern Europe they didn't know what 'honest' meant.

    In China they didn't know what 'opinion' meant.

    In the Middle East they didn't know what 'solution' meant.

    In South America they didn't know what 'please' meant. In Western Europe they didn't know what give' meant.

    And in the USA they didn't know what 'the rest of the world' meant.

    UN Food Shortage Worldwide Survey.UN Food Shortage Worldwide Survey.

    The only question asked was:The only question asked was:

    Would you please give your honest opinion about solutions toWould you please give your honest opinion about solutions to

    the food shortage in the rest of the world?the food shortage in the rest of the world?

    The survey was a huge failure....The survey was a huge failure....

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    Outline

    A. What are the major categories of globalhealth determinants?

    B. What are the most important?

    C. What are their relative contributions indetermining global health?

    D. Exercise

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    Outline

    A. What are the major categories of globalhealth determinants?

    B. What are the most important?

    C. What are their relative contributions indetermining global health?

    D. Exercise

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    Meta-theories of Health Determinants

    Nutrition (Mc Keown, 1976)

    Public health technology (Preston, 1976)

    Economic growth - poverty reduction (Preston, 1976)

    Sanitation, hygiene and clean water

    Education, autonomy of women and maternal and childservices (Caldwell, 1986)

    Income Inequality (Wilkinson, 1992)

    Health behaviors (Mc Ginnis, 1993)

    Medical treatment (Bunker, 1994)

    Gene expression (Venter, 2001)

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    Frameworks of Health Determinants (I)

    Disease HealthCare

    Cure, care

    OtherFactors

    Clinical Epidemiology

    Healthcare Evaluation

    Health Services Research, etc.Source: Evans and Stoddart, 1994.

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    HEALTH CARE

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    OECD, 2005. Health at a glance

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    Source: Ontario Cancer Registry 1999

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    Frameworks of Health Determinants (II)

    DiseaseHealth

    Care

    Cure, care

    Other

    Factors

    Lifestyle Environment Biology

    Source: Evans and Stoddart, 1994.Clinical Epidemiology

    Healthcare Evaluation

    Health Services Research, etc.

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    BEHAVIOURS

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    Smoking and Lung Cancer: animal studies

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    and human studies

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    ENVIRONMENT

    (PHYSICAL AND SOCIAL)

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    Fig 1 Neighbourhood specific homicide rates (per 100 000 population per year) in relation

    to male life expectancy at birth (with effects of homicide mortality removed) for 77 communityareas of Chicago, 1988-93

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    BIOLOGY

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    STRESS AND ITS BIOLOGICAL TRANSLATION

    Stress is posited to get under the skin

    via different biological pathways

    including the hypothalamic-pituitary-

    adrenal (HPA) system

    People may differ in terms of

    psychological, biological and

    behavioural response to stressors

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    Frameworks of Health Determinants (III)

    Wellbeing Prosperity

    Individual

    Responses:

    Behavior

    Biology

    Social

    Environment

    Physical

    Environment

    Genetic

    Endowment

    Health

    &

    FunctionDisease

    Health

    Care

    Source: Evans and Stoddart, 1994.

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    Outline

    A. What are the major categories of globalhealth determinants?

    B. What are the most important?

    C. What are their relative contributions indetermining global health?

    D. Exercise

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    Kunst A 1998.

    Fig. 1. Probability of men in non-manual and manual classes dying between the ages 45 and 65.

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    Figure 3. Under-5 mortality rates by socioeconomic quintile of the household for selectedcountries based on data taken from the World Bank.

    Victora et al. Lancet 2003;362:233-41

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    Source: Davey-Smith (1996) Age adjusted mortality of 300 685 white American men by median family

    income of zip code areas in the United States. AJPH 1996;86:497-504.

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    1. The sport of choice for the urban poor is

    BASKETBALL.

    2. The sport of choice for maintenance level employees

    is BOWLING.

    3.The sport of choice for front-line workers isFOOTBALL.

    4. The sport of choice for supervisors is BASEBALL.

    5. The sport of choice for middle management is TENNIS.

    6. The sport of choice for corporate officers is GOLF.

    Socioeconomic status and sport of choice

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    Figure Life expectancy among males and females in India compared with United States, mid-1990

    from Sen (2002)

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    Inequality and health worlwide

    Babones (2007) Social Sciences

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    Source: De Vogli R, Mistry R, Gnesotto R and Cornia GA (2005) Has the relation between income

    inequality and life expectancy disappeared? J Epidemiology and Community Health

    Income inequality and life expectancy among wealthy nations

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    Fig. 1. Mortality in working age men by proportion of income belonging to the less well off half of households, US states

    (1990) and Canadian provinces (1991). Mortality standardised to Canadian population in 1991.State abbreviations: LA-Louisiana; MS-Mississippi; AL-Alabama; SC-South Carolina; FL-Florida; TX-Texas; CA-California; AR-Arkansas;

    NH-New Hampshire; MN-Minnesota. Province abbreviations: QC-Quebec; NS-Nova Scotia; NB-New Brunswick; ND-Newfoundland;

    PE-Prince Edward Island; ON-Ontario; AB-Alberta; BC-British Columbia; MB-Manitoba; SK-Saskatchewan

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    Outline

    A. What are the major categories of globalhealth determinants?

    B. What are the most important?

    C. What are their relative contributions indetermining global health?

    D. Exercise

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    WHO (2002). GLOBAL RISK FACTORS. High-mortality, developing REGIONS=subregions in D and E mortality strata. Lower-mortality, developing

    REGIONS=AMR-B, EMR-B, SEAR-B, and WPR-B subregions. Developed REGIONS=AMR-A, EUR, and WPR-A. The figure shows the estimate d

    mortality and disease burden for each risk factor considered individually. These risks act in part through other risks and act jointly with other risks.

    Consequently, the burden due to groups of risk factors will usually be less than the sum of individual risks.

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    WHO (2002).

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    Relative Influence of Health Determinants

    Societal/social

    characteristics

    Total Ecology

    Genes & Biology

    Health Behaviors

    Health Care

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    Now I can see the real picture