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Giant Cell Tumor of Bone

I K B A L A D I T A K W A A .

K O A S R A D I O L O G I R S U D 4 5 K U N I N G A N

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Giant Cell Tumor

80% jinak, 20% ganas

Sinonim: osteoclastoma

Insiden: 58% tumor tulang ganas, 15% tumor tulangjinak

Jinak predominant untuk wanita, ganas biasanya lakilaki

Usia: 2040 th

Rasa nyeri dan gangguan gerak sendi

Femur distal, tibia proksimal, radius distal, humerusproksimal (os sacrum 8%)

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Location

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Radiologik

Lesi di metafise meluas kearah subartikuler pada epifise

sudah menutup

Lesi lusen eksentris Sifat ekspansif dengan soap bubble appearance

Kadangkadang sulit membedakan antara jinak dan

ganas

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Radiology

Lytic lesion

Epipyseal

Eccentric or central Narrow zone transition

Cortical thinning

expansile No sclerotic margin

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DDx

Consider: Age & Location

Fibrogenic/Telangiectatic Osteosarcoma

MFH

Brown tumor

Chondroblastoma

ABC

Chondromyxoid fibroma (rare)

Mets / Myeloma

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