> Fixation > Processing > Embedding> Sectioning > Staining > Instruments

Innovative life science solutions

General Catalog

INDEX

Company 1

ATP 700 Automatic Tissue Processor 2

ATS 2010 Automatic Slide Stainer 4

ATS 200 Automatic Slide Stainer 6

Histo-Pro 200 Vacuum Tissue Processor 8

TEC 2900 Modular Tissue Embedding Center 10

TEC 2900 Cryo console 11

TEC 2900 Thermal console 11

TEC 2000 Paraffin Dispenser 12

TEC 3000 Histo Trim 13

Cito-Spin Cytology Centrifuge 14

MR 2258 Manual Rotary Microtome 15

MR 3000 Manual Rotary Microtome 16

MRS 3500 Ultra-Thin Semiautomatic Microtome 17

ARM 3600 Fully Motorized and Programmable Rotary Microtome 18

MC 4000 Microtome Cryostat Dual Compressor 19

MC 5000 Microtome Cryostat Dual Compressor 20

TEC 2500 Water Bath-Slide Dryer 22

TEC 2602 Slide Dryer 23

TEC 2601 Water Bath 23

Products for Histology and Cytology 24

The Histo-line Laboratories were founded in Milan in 1987.

We are a leading producer and distributor of products and instruments meant for diagnosis and research in: Histology, Cytology, Immunostocytochemestry, Cellular Biology, Molecular Biology, hematology, Veterinary.

Our products’ are conceived to satisfy a vast spectrum of human and veterinary research and diagnostic needs.

Our mission is to supply the best technological assistance to researchers in pursuit of excellence. We supply a vast selection of products and systems, such as Antibodies, DNA probes, automatic and manual revelation systems, reagents and instruments for processing, staining and diagnosis of human and animal tissues.

Company

1

ATP 700Automatic Tissue Processor Automatic Tissue Processor

ATP 700

Is a Linear closed Tissue Processor, a compact instrument designed with latest technology for complete automatic dehydration and filtration of biological samples, up to final fixing in wax. Includes 14 stations for simultaneous processing of two samples baskets programmable separately.All the reagent and paraffin containers are completely closed to prevent evaporation. Electrostatic filter prevent solvent odors and pollution. ATP 700 can be programmed for immediate or delayed start, immersion time can be set from 1 minute to 99 hours and 59 minutes.

2

All functions are settable trough us-er-friendly, easy-to-use control panel. All processing steps are visualized on real time display

33

Technical SpecificationsNumber of Stations: 14Number of Stations 14Number of Paraffin Stations 4Number of stored programs: 6Total samples capacity 150Station capacity 1500 mlProgrammable infiltration time per station From 1 min. to 99 h 59 min.Paraffin temperature range: From 50°C to 75°C increments 1°CAgitation : 4 times every 5 min.Delayed start: 99h 99 min.Drain time: 0 sec. to 99 sec.UPS: OptionalNominal supply voltage: 220 V / 50 Hz 110 V / 60 HzMaximum power draw: 1000 VADimension:Width: 1 400 mmDepth: 500 mmHeight: 550 mmWeight:142 Kg.

4

ATS 2010Histo Line ATS 2010 is a compact, bench top, linear slide stainer designed to process biological samples from dewaxing to histo-cytology staining. The unique linear design offers reliable technique in a small space in the labo-ratory. Histo Line ATS 2010 includes 18 stations, 15 rea-gents, 1 slides rinse, 1 heated inlet station, 1outlet slides racks station. Process capacity is 47 slides continuously . All the reagent containers are completely closed to prevent evaporation. Electrostatic filter prevent solvent odors and pollution. ATS 2010 can be programmed for immediate or delayed start. Immersion. Time can be set from 1 minute to 99 hours and 59 minutes.

ATS 2010Automatic Slide StainerLinear, closed for Histology & Cytology

All functions are settable trough the easy-to-operate Touch Screen Control Panel. All processing steps are visualized on real time display.

Reagent library is freely settable by control panel

5

Technical SpecificationsNumber of Stations: 18Number of Reagents station: 15Number of stored programs: 6Number of samples in process: 47 Slides per basket Continuous processingCapacity of single tray: 1000 mlSetting range time for each step: From 1 min. to 99 h 59 min.Temperature range: From ambient to 75°C increments 1°CAgitation: 4 times every 5 min.Delay time setting: 99h 99 min.UPS: OptionalNominal supply voltage: 220 V / 50 Hz 110 V / 60 HzMaximum power draw: 400 V/A

DimensionWidth: 1400 mm Depth: 500 mmHeight: 550 mm Weight: 142 Kg.

5

6

ATS 200ATS 200 is specially designed for simultaneous process of different staining protocols, allows continuous unload & reload without interrupting staining cycle.All functions, menu-driven programming, incubation times and sequence of use of reagent stations are freely programmable and controlled by the touch screen panel. Ergonomic design, integrated oven for slides drying, digital electronic temperature control, movement parts are in bearing linear guide for high precision on axis.

ATS 200Automatic Slide Stainer for Multiple Histological & Cytological Routine Stains

designed for simultaneous process of different staining protocols, allows continuous unload & reload without interrupting staining cycle.All functions, menu-driven programming, incubation times and sequence

7

Technical SpecificationsNumber of Stations: 26Number of reagents Stations: 18Number of wash Stations: 3Number of waiting Stations: 3Number of programs: 5Loading capacity per rack: 30 slides, 200 staining per hourCapacity of single tray: 450 mlIncubation time setting: From 1 min. to 99 h 59 min.Temperature range: From ambient to 75°C increments 1°CUPS: OptionalSupply Voltage: 220 V / 50 Hz 110 V / 60 HzPower draw: 300 V/A

Dimension: Widht: 1200 mm Depht: 500 mmHight: 600 mm Weight: 110Kg.

8

Display and Software:Large color Liquid Crystal Display (LCD) User-friendly, intelligent software.Alarm system to reminder wrong operation and troublesMultiple specimen protection system.

HISTO-PRO 200Histo-Pro 200 set a new standard in vacuum tissue processing. His unique reagent monitoring and management delivers significant reagent cost savings. Superior process control, functional design, and precise temperature control ensure optimum specimen quality.An active extraction process ensures efficient paraffin cleaning, which extends paraffin life, improves tissue quality, and reduces operating costs.User safety is enhanced by a fully enclosed fume system and by theimproved reagent bottle and cabinet design to prevents the risk of contact and reagent carry-over.

Histo-Pro 200Vacuum Tissue ProcessorExtremely Reliable

Large color Liquid Crystal Display (LCD)

Multiple specimen protection system.

Vacuum Tissue Processor

Display and Software:Large color Liquid Crystal Display (LCD) User-friendly, intelligent software.Alarm system to reminder wrong operation and troublesMultiple specimen protection system.

Extremely Reliable

NEW

9

Capacities:15 programs that consist of up to 9 reagent and 3 paraffin wax steps.Time per program step: 0 to 99 hours, 59 minutes.Up to 200 cassettes can be processed (300 on Histo-Pro 300)Wax clean program.9 reagent bottles.3 wax baths.3 cleaning solution bottles.2 condensate bottle.Maximum bottle volume: 4.0 l

Technical DataNominal voltage: AC220V Nominal voltage: AC220V Nominal frequency: 60HZMain fuses: 10A Nominal power: 1000 VADry weight, unpacked: approx. 100 kgWeight, packed: 120 kgOperating temperature range: 15 °C to 35 °CRelative humidity: 10 to 80 %Recirculation (pump in/out): ON/OFFTime between cycles: 15 min

RetortCapacity: 200 cassettes (300 on HistoPro 300)Reagent volume: 5.3 Lt.Temperature (paraffin): 50°C - 65°CTemperature (reagents): ambient or 35°CTemperature (cleaning reagents): 50°C -65°CTemperature accuracy: + 1°C Filling time: up to 5 min Drain time: up to 5 min Impregnation vacuum: -70 kPa (g)Impregnation pressure: 35 kPa (g)Fill vacuum: -70 kPa (g)Drain pressure: 35 kPa (g)

Paraffin wax bathsNumber of baths: 3Volume (liters): 4.0 l per bathMelt time: approx. 3 hrsTemperature: 50°C - 65°CTemperature accuracy: + 1°C

10

TEC 2900Modular Tissue Embedding Center

TEC 2900TEC 2900 is the ultimate paraffin dispensing module for modern histology labs.More than 4,5 liter capacity. Ergonomic large working surface with embedding cassettes and base molds removable trays that can be set at different temperatures.All functions are controlled via an easy-to-read display, including the temperature settings for left and right hand warming trays, paraffin reservoir, and working surface.Working days and times can be programmed for automatic instrument operation. Large cold spot allow tissue orientation even with Super Mega Cassette

Technical Specifications:Nominal supply voltage: 220 V/50Hz 110 V/60HzMaximum power draw: 1000 VATemperature range of paraffin: ambient to 75°C increments +/- 1°C

CapacityParafifn reservoir 4,5 Lt Cassette /mold trays 1,4 Lt

Dimension:Width:560 mm Depth: 640 mm Height: 400 mm Weight: 26 Kg

11

TEC 2900Cryo console

TEC 2900Thermal console

Technical Specifications:Nominal supply voltage: 220 V/50Hz 110 V/60HzMaximum power draw: 110 VATemperature range: ambient to – 20°C increments +/- 1°C

Dimension:Width: 340 mm Depth: 600 mm Height: 390 mm Weight: 24 Kg

Technical Specifications:Nominal supply voltage: 220 V/50Hz 110 V/60HzMaximum power draw: 400 VATemperature range: ambient to 75°C increments +/- 1°CCapacity:Paraffin 2,5 Lt

Dimension:Depth: 300 mm Width: 540 mm Height: 400 mm Weight: 7,5 Kg

TEC 2900 Cryo console is composed of a cooled work surface held to chill the paraffin blocks rapidly. The easy cleaning teflon coated surface allows a minimum ice formation. Cryo console can be used as a stand alone unit near the microtome station.

TEC 2900 Thermal console stores and warms samples of processed tissue specimens awaiting paraffin embedment in a large paraffin tank.

12

TEC 2000Paraffin Dispenser

TEC 2000Tec 2000 is equipped with 10 Liter hight-capacity tank, preheated at controlled temperature. No wait time to melt more paraffin when an embedding center runs out !

Technical SpecificationsNominal supply voltage: 220 V/50Hz 110 V/60HzMaximum power draw: 330 VATemperature range: ambient to 75°C increments +/- 1°C

Dimension:Width: 400 mm Depth: 300 mm Height: 370 mm Weight: 10 Kg

10 Liter of liquid Paraffin on Demand

13

TEC 3000Histo Trim

TEC 3000

TEC-3000 Wax Trimmer is a practical device designed to re-move excess of paraffin from the embedding cassettes after inclusion of specimens. Scraping the embedded block on the ”grooved” plane heated surface, excess paraffin will be re-moved leaving the cassette clean ready to be set properly on the clamp of the microtome.

No more wax residueon your working table!

Technical SpecificationsTemperature range: > 75 ° CPrecision in the control of temperature: ± 1 ° CNominal supply voltage: 220 V ± 10% 50HZ Or 110V ± 10% 50/60HzDimensions Width: 200 mm Depth: 160 mm Height: 175 mm Weight: 2,5 Kg

14

Cito-SpinCytology Centrifuge

Technical SpecificationsMax RPM: 3,000 rpm Max RCF: 1,057 x g Maximum Capacity: 12 Slide x 6cc Timer: 99min 59sec or “free” for long run Braking rates: 10 setting Programmability: 10 memory Digital display: Speed, Time, Brake, Program Drive Motor: High torque DC Motor Power: 220V, 50/60Hz, Single Phase, 0.5Kw C. Specimen range: 0,5 to 6 cc.Dimension:Width: 360 mm Depth: 410 mm Height: 280 mm Weight: 24 Kg

Cito-Spin

Cytological centrifuge is controlled by microprocessor. Program save and recall up to ten protocols. Gentle stop and fast braking: pre select 10 braking rates. Warning indicators for imbalance, over speed, door open, setting failure. Rotor imbalance is detected and immediately signaled to operator.

15

MR 2258Manual Rotary MicrotomeThe essential Microtome for routine sectioning

Technical SpecificationsSection thickness range: 0.5~60μmSetting value: 0.5~2μm increment 0.5μ 2~10μm increment 1μm 10~20μm increment 2μm 20~60μm increment 5μmTrimming thickness range: 1~60μmMinimum Setting value: 0.5μmPrecision Error: ±5%Maximum Specimen Size: 60x50mmObject Feed: 28mm Vertical Stroke: 60mmSpecimen return range: 0~28mmDimension:Width: 500 mm Depth: 460 mm Height: 3000 mm Net Weight: 23.3kg

16

MR 3000Manual Rotary Microtomewith accurate trimming functionSafe, Confortable, Reliable

Technical Specifications:Section thickness range: 0~60μmSetting value: 0~20μm increment 1μm 20~60μm increment 5μmMinimum Setting value: 1μmPrecision Error: ±5%Maximum Specimen Size: 60x50mmTrimming Setting Mode: 15μm or 35μmSpecimen Retraction Range: 90μmSpecimen retraction range of 90μm can be shut offObject Feed: 30mm,Vertical Stroke: 70mmSpecimen Orientation System: 8° X/YDimension: 570mmx500mmx300mmNet Weight: 33kg

Manual Rotary Microtomewith accurate trimming functionSafe, Confortable, Reliable

Manual Rotary Microtomewith accurate trimming function

17

Digital display

MRS 3500Ultra-Thin Semiautomatic MicrotomeTwith High-precision motorized specimen feedsection thickness from 0,25 μm

Technical SpecificationsSection thickness range: 0.25~60μm 0.25~1μm increment 0.25μm 1~10μm increment 1μm 10~20μm increment 2μm 20~60μm increment 5μmTrimming thickness range: 0.25~60μmMinimum setting value: 0.25μmObject feed: 28mmVertical stroke: 60mmMaximum specimen size: 50 x 50mmPrecision error: ±5%Working Voltage: AC220V 50Hz AC110V 60HzDimension: 150VA Net weight: 24kg

18

Technical SpecificationsSection thickness range: 0.5~100μ 0.5~2μm increment 0.5μm 2~10μm increment 1μm 10~20μm increment 2μm 20~100μm increment 5μmTrimming thickness range: 1~600μm 1~10μm increment 1μm 10~20μm increment 2μm 20~100μm increment 10μm 100~600μm increment 50μmMinimum setting value: 0.5μmObject feed: 28mmVertical stroke: 60mmSpecimen retraction range: 20μmSpecimen clamp rotated at an angle of 360 degrees.Maximum specimen size: 50 x 50mmPrecision error: ±5%Working Voltage: AC220V 50Hz / AC110V 60HzPower Draw: 150VA Dimension: 580x360x310mm Net weight: 35kg

Function and characteristic:Motorized drive, Allows motorized and manual sectioning. Compatible Embedding Material paraffin, plastic. The cutting and trimming function can be finished by the control system. The hand wheel can be locked at any position to ensure the safety of operation. The large waste tray can be Exchanged arbitrarily. Two kinds of specimen clamp can be changed conveniently. Alarm system. Manual and automatic section can be switch arbitrarily. Four speed of section: 25 circle/minute, 35 circle/minute, 45 circle/minute, 55 circle/minute. Switch arbitrarily between section and trimming. Alarm system for horizontal and vertical stock limit, protection system for motor surcharge.

ARM 3600Fully Motorized and Programmable Rotary MicrotomeThe State-of-the-Art for high quality section

19

MC 4000Microtome Cryostat Dual CompressorUVC lamp Decontamination Automatic Defrosting

Technical SpecificationsSection thickness setting: 1-60 μm 0-10 μm in 1 μm increments 10-20 μm in 2 μm increments 20-60 μm in 5 μm incrementsMaximum specimen size: 50x70 mmHorizontal specimen feed: 28 mmVertcal specimen stroke: 59 mmSpecimen orientation: 8° (x,y,z axis)Trimming: motorized coarse feedMotorized coarse feed: 2 speeds Rapid: 0,8mm/sec Slow: 0,2 mm/sec

Cooling capacity:Temperature setting range: 0°C to –35°CCooling down time to –35°C: appr. 4 hoursChamber defrosting: programmable or manual1 automatic defrosting cycle / 24 hour duration 9 min.Freeze shelf temperature: -40°C

Nominal supply voltage: 220 V / 50 Hz 110 V / 60 HzMaximum power draw: 450 VA

Dimension:Width (excluding handwel): 705 mm Width (including handwel): 760 mmDepth: 640 mm Height: 1115 mm Weight: 152 Kg

MC 4000Histo Line MC 4000 is a semiautomatic rotary microtome cryostat, dual compressor with UVC lamp decontamination and automatic defrosting. MC 4000 is provided with disposable blade holder cooled with separate freezing circuit , anti roll device and adjustable cutting angle. Easy to operate, all function are settable through keyboard. The motorized coarse feed control is accessible through a separate control panel.

20

MC 5000Microtome Cryostat Dual CompressorUVC lamp Decontamination Automatic Defrosting

MC 5000Histo Line MC 5000 is a semiautomatic rotary microtome cryostat , dual freezing system with UVC lamp decontamina-tion and automatic defrosting. MC 5000 is provided with dis-posable blade holder , anti roll device and adjustable cut-ting angle. Easy to operate, all function are settable through keyboard. The motorized coarse feed control is accessible through a separate control panel. Cleaning vacuum system.

21

The smooth orientation device allows specimen alignment.

Anti-roll device Specimen alignment deviceDisposable blade holder with adjustable cutting angle suitable with hall disposable blades. The glass anti-roll device is integrated into the holder. Clening vacuum system.

Technical SpecificationsApprovals: CE IVD

Microtome:Section thickness range: 1-60μm AdjustableIncrement: 1μm, Increment: ±20‰Trimming thickness range: 10~300μm AdjustableIncrement: 10μm, Increment:±20‰Specimen retraction: 20μmHorizontal stroke: 25mmVertical stroke: 45mmSpecimen orientation: 8°(X,Y,Z three directions)

CryostatVoltage: 220V±10% Frequency: 50HzPower: 850 V/AChamber temperature: -10°C ~ -35°C AdjustableFreezing shelf temperature: =-50°CNumber of freezing station: 18Peltier number: 2Refrigerant: R404a, 300g±10gCompressor oil: 0.6L EMKARATE RL-22S, ICI Dimensions:Width(No hand wheel) 680 mm Width(With hand wheel) 826 mmDepth: 700 mm Height: 1150 mm Weight: 126 kg

22

TEC 2500 Water Bath-Slide DryerAll in OneCompact size, space saving. But not limited!

TEC 2500TEC 2500 is a practical device designed to provide in a single compact instrument water bath, slide dryer and oven. Temperatures can be programmed separately and are shown on an LED display while the selected temperature set value is memorized by a battery backup system.

Technical SpecificationsNominal supply voltage: 220 V/50Hz 115 V/60HzMaximum power draw: 600 VATemperature range: 75°C increments +/- 1°C

Dimension:Width: 550 mm Depth: 340 mmHeight: 140 mm Weight: 9 Kg

23

TEC 2602 Slide Dryer

TEC 2601Water Bath

Technical SpecificationsNominal supply voltage: 220 V/50Hz 115 V/60HzMaximum power draw: 300 VATemperature range: > 75°C incrementos +/- 1°C

Dimension:Width: 324 mm Depth: 272 mmHeight: 82,5 mm Weight: 2,75 Kg

Technical SpecificationsNominal supply voltage: 220 V/50Hz 115 V/60HzMaximum power draw: 350 VATemperature range: 75°C incrementos +/- 1°C

Dimension:Width: 328 mm Depth: 300 mmHeight: 86 mm Weight: 2,4 Kg Capacity: 2 lt

24

Histo-Line offers a complete range of products for Histology and Cytology

STORAGE

Slides Paraffin Block

Super Mega Cassettes

25

Histo-Line offers a complete range of products for Histology and Cytology

PROCESSING & FIXATION

STAINING

SECTIONING

EMBEDDING

PROCESSING& F& FIXATION& F& FIXATION& F

Histo Line Laboratories S.r.l. Via Brembo, 2720139 Milano ITALYTel:+39 0255230061 Fax:+39 0255213764Email: histoline@histoline.com www.histo-online.comwww.histoline.com

Distributedby: