Gene TherapyGene Therapyand and

Genetic EngineeringGenetic Engineering

Your Goals:

• Create a Concept Map to organize what you know about gene therapy.• Use the Learn.Genetics gene therapy

website to help you.

• Integrate what you have learned about Genetic Engineering into your Gene Therapy Concept Map.• Gene Therapy Vector Engineering Project.

Concept Map Overview

• A concept map is a technique used to organize information or thoughts.

• Concept maps allow you to organize lots of information into a form that is easily understood.

• Concept maps allow you to visualize connections within the information.

Gene Therapy Word List • Targeting the right

tissue• Immune response• Vectors• Single gene

disorders• Naked DNA• Activating the gene• Disruption of existing

genes• in vivo

•Integrating the gene•Fit inside vectors•Keys to success•Viruses•Candidate diseases•Liposomes•Procedure•Integration into the germline•Risks/Challenges•ex vivo

Gene Therapy AND Genetic Engineering

Word List • Plasmids• Hemophilia• Identical DNA copy• Recombinant DNA

tools• ADA Deficiency• Restriction Enzymes• Adeno Associated

virus• Sickle Cell Anemia

• Herpes Simplex Virus

• Identical organism copy

• Ligase• Huntingtons Disease• Retrovirus• Cloning• Adenovirus

Creating a Concept Map

Step 1– Start by placing your Main Idea in the

center circle or graphic.

Step 2– Decide which of the choices are your

Large Topics and place them in a circle around your Main Idea.

– Draw lines connecting the Main Idea and the Large Topics.

Main Idea

Large topic

Large topic

Large topic

Large topic

Creating a Concept Map

Step 3– Decide which Subtopics belong with

each Large Topic and place them near the appropriate branch.

• Cut the Topics out of the Word List so you can easily rearrange them until you have it right.– Paste your Concept Map to your poster.

Concept Map!

Main Idea

Large topic

Large topic Large topic

Large topic subtopicssubtopics

subtopicssubtopics