Gender and Sex Influence on Disease Pattern

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    Alexis R. Jones

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    According to the World Health Organization,

    Gender: refers to the socially constructed roles,

    behaviors, activities, and attributes that a given societyconsiders appropriate for men and women

    and

    Sex: refers to the biological and physiologicalcharacteristics that define men and women

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    Cultural norms

    Many women are unable to go tohealth clinics

    Higher lung cancer in men Higher number of women with

    HIV/AIDs

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    Women have a greater risk of developing diseases caused by

    a defective metabolic and immune system (Alzheimers disease,

    type 1 diabetes, rheumatoid arthritis, lupus)

    Premenopausal women recover from stroke sooner and withless disability than men of the same age or postmenopausal

    women

    Brain regions are varied in size -emotions, memory

    Hippocampus larger in women effects short term memory? Size alone doesnt drive function hormones and genes

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    Subject placed in a scanner with neutral scenes followed by

    scenes to stimulate a response

    Women tested at beginning of menstrual cycle and ovulation

    Felt no mood change, but showed greater stress activity at beginning ofmenstrual cycle (adaptation?)

    Men showed similar stress activity to women at the beginning of

    menstrual cycle

    Higher rates of depression and anxiety in women

    Men with depression/anxiety less sensitive to trauma

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    Men Women

    Heart Heart

    Cancer Cancer

    Respiratory Stroke

    Stroke Repiratory

    Type II Diabetes Alzheimers

    Type II Diabetes

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    Causes 29% of total deathsworldwide

    Higher prevalence in women,yet higher under diagnosis

    Heart Attacks andThrombolytics

    Exercise/PharmacologicStress Tests

    Surgery-Balloon Angioplasty

    Need for early intervention

    http://www.drugdevelopment-

    technology.com/projects/exanta/images/exanta2.jpg

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    Schizophrenic women have

    higher levels of

    testosterone than men

    Onset is delayed in women Female hormones protect

    nerves

    less maintenance on

    antipsychotic drugs

    Greater rate of head trauma

    in men

    Slower maturation of men

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    Men: physical, verbal, and sexual aggression, tendency to

    wander, socially inappropriate behavior

    Women: emotionally unstable, hoarding, refuse help,depression, delusions

    Hormones (estrogen) may play a large role, but mostly gender

    related differences due to longer life span of women

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    As society and culturalnorms evolve increase health

    professionals' awareness ofthe role of gender norms,

    values, and inequality inperpetuating disease,disability, and death

    promote societal changewith a view to eliminatinggender as a barrier to goodhealth.

    Sex specific treatmentsand prevention Prenatal Brain

    http://www.provost.duke.edu/images/Research.jpg

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    http://www.who.int/gender/whatisgender/en/

    http://www.sciencedaily.com/releases/2007/07/070727183141.htm

    http://www.womensheart.org/content/heartdisease/gender_differen

    ces.asp http://www.who.int/gender/genderandhealth/en/index.html

    http://www.sciencedaily.com/releases/2010/11/101118123840.htm

    http://www.everydayhealth.com/alzheimers/alzheimers-and-gender.aspx

    http://www.mayoclinic.com/health/womens-health/WO00014 http://www.mayoclinic.com/health/mens-

    health/MC00013/NSECTIONGROUP=2

    http://www.health.am/psy/more/schizophrenia-in-women-and-men/