FUNCTIONS AND STRUCTURE OF A MEDICAL …€¦ · Web viewApril 3, 2009. GENERAL INSTRUCTIONS FOR COMPLETING THE DATABASE. Each question in the database is preceded by the relevant

April 3, 2009GENERAL INSTRUCTIONS FOR COMPLETING THE DATABASE

Each question in the database is preceded by the relevant LCME accreditation standard. In some cases two standards are closely related, and the questions are germane for documenting compliance with each of the two standards. Additional related information is sometimes contained in the responses to questions that deal with other standards; in those cases, cross-references to the additional information are included in italics. The cross-references are intended to help self-study groups and the survey team identify all relevant data for assessing compliance with standards.

For comprehensive instructions regarding database completion, please refer to the document “Background and Instructions for Completing the LCME Medical Education Database and Institutional Self-Study,” available on the LCME web site at: http://www.lcme.org/database.htm.

The school should maintain a master database that contains all of the information used for the self-study. When it becomes necessary to update database sections after the self-study report is complete but prior to the survey visit, the school should create separate database pages containing the updated information only.

Most questions require a narrative answer or completion of a table; in some cases, it will be necessary to duplicate a blank table (for example, to summarize each of the school’s clinical teaching sites). Use as much space as necessary to answer each question completely, or to complete the tables. The tables may be modified to fit the circumstances specific to the school.

Any supporting documents that are requested in the database (e.g., bylaws, organizational charts, policy documents) should be compiled in a separate (red) binder, divided by tabs for each section of the database; do not include such appended materials in the individual database sections.

The header on each page should indicate the most recent academic year for which information is available at the time of the self-study, not the academic year in which the database is being completed; in most cases, the year for which information is available will be the 2008-2009 academic year (July 1, 2008- June 30, 2009) for self-studies concluding in 2009-2010. When the requested data are for a different time period than that indicated in the header, the applicable time period should be included in the response to the question.

If database information is updated after completion of the self-study, the academic year listed in the header should be changed accordingly, and marked with the word “Update” in the header along with the year shown (e.g., “Update 2009-10”). Note that changing the header will affect all pages of a database section; therefore, a fresh (blank) copy of the database section should be used for updates.

If requested information is available from the school’s web site, make sure to print a copy of the web site information for the master database maintained by the school. Changes to such documents after completion of the self-study should be printed and stamped “Updated” to indicate that they have changed, and included in the updated database. In addition, database pages that list URLs of modified web pages should indicate that the web site information has been altered from the original data available to the self-study groups.

The database copies sent to the LCME Secretariat should include printed copies of any information referred to by website URL. If the document is long, please include the table of contents and only the relevant sections. The Secretariat is required to maintain complete print records of all database information.

LCME Medical Education Database 2009-10 I. Institutional Setting

For US schools, most of the Key Quantitative Indicators (Part A of each database section) can be completed using information contained in the Longitudinal Statistical Summary Report. This report is prepared annually by the AAMC Section for Institutional, Faculty, and Student Studies, and sent directly to the dean.

SPECIAL INSTRUCTIONS FOR SECTION I: INSTITUTIONAL SETTING

No special instructions are included for this section.


BACKGROUND INFORMATION ABOUT THE SCHOOL

a. Insert a copy of the school’s current entry in the AAMC Directory of American Medical Education.

b. Indicate on a separate page any changes in administrative positions or personnel that have taken place since the directory was published.

Changes to AAMC Directory of American Medical Education since last publication:

Las sentence of the overview should read “The School of Medicine is one of six professional schools………”

Clinical facilities: Interim LSU Public Hospital (Medical Center of Louisiana in New Orleans); Children’s Hospital; University Medical Center – Lafayette; Earl K. Long Medical Center – Baton Rouge; East Jefferson General Hospital; New Orleans Adolescent Hospital; LSU Hospital – Depaul Campus; Ochsner Medical Center; Ochsner – Kenner; Ochsner – Baptist; Touro Infirmary; West Jefferson Medical Center; Our Lady of the Lake; Baton Rouge General Hospital; Lake Charles Memorial; LSU – Bogalusa Medical Center; LSU Baton Rouge Mid-City Clinic.

Medical School Administrative Staff Coordinator, Office for Research and Vivarium Director should be listed under University

Officials Director, Library should be listed under University Officials Personnel changes:

- Associate Dean for Healthcare Quality and Safety: Dwayne Thomas, MD- Associate Dean for Alumni Affairs and Development: Cathi Fontenot, MD- Associate Dean for Clinical Affairs: Thomas E. Nolan, MD, MBA- Director of Clinical Science Curriculum: Robin English, MD

New positions:- Director of Research: Jean Jacob, PhD- Director of Faculty Development: Paula Gregory, PhD

Department and Division or Section ChairsBasic SciencesGenetics

New department head: Jay K. Kolls, MD

Clinical SciencesMedicine

New section chiefs:- Endocrinology and Metabolism: William T. Cefalu, MD (pending University approval)- Gastroenterology: Daniel Raines, MD (Interim)


- Pulmonary and Critical Care: Judd Shellito, MD Section of Nutrition and Metabolism not a separate section any longer

Obstetrics and Gynecology New section chief:

- General Gynecology: Martha Brewer, MD

Orthopaedics New department head: Andrew King, MBBCh

Pathology Epidemiology not a section in the department any longer

Pediatrics New section chiefs:

- Cardiology: Robert J. Ascuitto, MD- Gastroenterology and Nutrition: Paul E. Hyman, MD

Psychiatry New section chiefs:

- Psychology: Phillip T. Griffin, PhD- Social Work: Michelle M. Many, MSW, LCSW

Surgery New section chiefs:

- Pediatric Surgery: Evans P. Valerie, MD Sections closed:

- Bariatric - Transplant

Correction to Department Head: Dr. Baker not interim head Correction to name of Trauma section: should be Trauma/Critical Care

c. Provide a brief history of the medical school, noting any key points in the school’s historical development.

The Louisiana State University School of Medicine was authorized by Legislative Act 145 of 1877 and founded formally by the LSU Board of Supervisors on 3 January 1931. The School officially opened on 1 October 1931 in a nine story building at 1542 Tulane Avenue adjacent to the 2200 bed Charity Hospital of Louisiana at New Orleans. This location for the medical school was selected primarily because Charity Hospital provided the patients and medical facilities necessary for the development of outstanding programs in medical education and research. There have been several reorganizations of the administrative structure of the School of Medicine and changes to its name; it now is known as the LSUHSC School of Medicine in New Orleans. Founded as a small school with a mission of educating physicians for the State of Louisiana and caring for the indigent patients of the New Orleans region, it has grown dramatically into a robust, resilient institution known for training excellent physicians, its commitment to the medically under-served, and notable research programs. Like many public medical schools, it is not state supported, but rather state assisted; nonetheless, the state support has been constant as demonstrated by the investments it has made in our campus and our faculty since inception.


Since its creation, the School of Medicine has graduated over 7850 physicians. The majority of practicing physicians in Louisiana are alumni of the School of Medicine or have trained in its residency or fellowship programs.

The first 28 matriculants, graduating in 1933, were third year transfer students. The first four year class graduated in 1935. Class size was increased incrementally from 100 in 1949 to approximately 165 in 1975 and it remained at this level until recently. With the entering class of 2007, the base number of students accepted was raised to 180; this increase accommodates the successes of the Rural Scholars Track and the small, but significant, number of non-resident MD/PhD candidates, and non-resident alumni children who matriculate in the first year class.

With growth of the student body, faculty, and research activities, additional space was needed. Hence, in 1954, a nine story addition to the original building (now known as the Clinical Education Building) was completed. Another five story expansion to the Clinical Education Building was completed in 1964 and included parking facilities. In the same general timeframe an 11 story residence hall and student center was built nearby across Claiborne Avenue. This latter project sparked the dramatic western expansion of the campus in proximity to then-named Hotel Dieu Hospital which provided in-patient and limited out-patient facilities for the private faculty practice that took place outside of Charity Hospital.

Since these changes to the original medical school building, we have experienced a succession of building projects to support our educational and research missions. The Medical Education Building (MEB)(1901 Perdido Street) was completed in 1981; it provides space for much of the teaching for the pre-clinical curriculum, most of the Basic Science Departments, the Department of Pathology, and the Section of Pulmonary Medicine and Critical Care. It is located adjacent and connected to the Residence Hall. The MEB has benefited from recent updates to the roof, the morgue for the anatomy labs, the multi-disciplinary teaching labs, the cafeteria, the main lecture rooms, and many support spaces and a major project on the air handling system is also underway.

A facility housing an outpatient ambulatory clinic, research laboratories, and teaching space (2020 Gravier Street) was completed in 1986 using principally self-generated funds. A key donation from the Lions Foundation anchored construction funding, which explains in part the informal moniker, The Lions Building. This building and its upper floor expansion continue to accommodate the Department of Ophthalmology and the Neuroscience Center. The Student Learning Center was constructed in 2001 on the ground floor of the Lions Building, but it was destroyed in the flooding that occurred following Hurricane Katrina. The Student Learning Center is being relocated to the sixth floor of the same building (expected completion Spring 2009), in proximity to the recently completed Center for Advanced Practice (completed in 2008), a high-technology simulation and learning center used by students, residents and fellows, practicing physicians, and other constituents. No clinical activities have taken place in the Lions Building since Hurricane Katrina. This building connects with the Nursing and Allied Health Professions Schools Building which opened in 1985.

In 1988, construction was completed on the Resource Center, providing space for the Ische’ Medical Library, Computer Enterprises, the bookstore, the credit union, the Chancellor’s Office, and key operations for the campus administration, including human resources, accounting, payroll, grants and contracts, and the LSUHSC Office of Research.

The final major construction project supporting the School of Medicine, the Clinical Sciences Research Building, was completed in 2000. This building has replaced the research laboratory facilities in


the original medical school building and is a state-of-the-art facility with a vivarium and high technology equipment. It houses the Departments of Genetics and Otorhinolaryngology, the Alcohol Research Center, the Gene Therapy Program, the Stanley S. Scott Cancer Center, and the laboratory activities of several of the clinical science departments. While not “new” construction, other enhancements to the campus have, however, continued, and in 2004 a new residence facility, Stanislaus Hall, was completed in a renovated nursing school building. A full service fitness center (opened in 2006) is also located within Stanislaus Hall.

In 1965, the Louisiana Legislature authorized the creation of a second LSU medical school in Shreveport and the LSU Medical Center (later renamed as the LSU Health Sciences Center) was formally created for the two medical campuses. In approximately the same period, the School of Medicine in New Orleans was given expanded responsibility for developing teaching programs and staffing indigent patient care at the public hospitals in Baton Rouge, Lafayette, Lake Charles, and Bogalusa. (The LSU medical school at Shreveport shared a common Chancellor with the LSUHSC School of Medicine in New Orleans until late 2000 when the governance of the two LSUHSC campuses was separated and a Chancellor for LSUHSC Shreveport was named.)

The downturn in the state’s economy in the late 1980s and early 1990s led to a dramatic reduction in the size of Charity Hospital. Reductions in bed capacity in the outlying Charity Hospitals in smaller Louisiana cities forced closure of many of their residency programs. In 1993 with the state economy rebounding, more change to the clinical resources occurred when the state acquired Hotel Dieu and renamed it University Hospital; initially this facility was administered by the Louisiana Health Care Authority and, subsequently, with the passage of state legislation in 1997, by the LSU Health Care Services Division. The LSU Health Care Services Division continues to manage and operate the state public hospitals in Baton Rouge, Lafayette, Bogalusa, and several other cities. University Hospital formally became part of the Medical Center of Louisiana in New Orleans (MCLNO) and the two campuses were the major teaching sites for the medical school for over a decade. The “Old Charity” campus has remained closed since Hurricane Katrina and the University Hospital facility has been renovated and reopened as the Interim LSU Public Hospital.

While much of the clinical training experiences for our students remain focused in the state public hospital facilities, largely in New Orleans, Baton Rouge, and Lafayette, and on treating the medically under-served patients that seek care there, the School has many cooperative training agreements with private community hospitals and clinics and with a large number of volunteer faculty members and preceptors. These internal and external relationships form the core of our clinical teaching of medical students, residents and fellows. Planning is underway for the replacement facility for MCLNO in a large adjacent plot of land where both the New Orleans Veterans Medical Center and the LSU teaching hospital will be located; land acquisition for these facilities is underway.

Of course, the history of the School of Medicine would not be complete without a brief account of the remarkable events of the 2005-2006 academic year. Hurricane Katrina made landfall slightly east of New Orleans early on 29 August 2005. The storm and its surge breached more than 50 canal levees and over the next two days 80% of the City of New Orleans was flooded with up to 15 feet of water. Much of the city remained under water for weeks and, as a consequence, the flooding devastated the city and its infrastructure, the LSUHSC New Orleans campus, Charity Hospital, and many of the other community hospitals used for teaching. Overcoming enormous obstacles of physical dislocation and in communication, and also in the context of tremendous personal losses on the part of many of our students, house officers, and faculty and staff, School of Medicine operations were restored quickly. Clinical clerkships resumed no later than three weeks after the storm for individual students, mainly in


Baton Rouge and Lafayette, and preclinical classes resumed within four weeks of the storm, on 26 September 2005. A revised pre-clinical curriculum and course schedule was implemented at the Pennington Biomedical Research Center in Baton Rouge. By May 2006 most of the administrative functions of the medical school had resumed in New Orleans and by August 2006 preclinical classes resumed in the Medical Education Building. Extensive renovations have been completed or are under way for all School of Medicine buildings damaged by Hurricane Katrina. University Hospital (now Interim LSU Public Hospital) has been upgraded and functions as a primary training site while plans for a replacement for Charity Hospital proceed.

There have been sixteen (16) Deans of the School of Medicine since its inception, including fourteen (14) permanent and two interim or acting deans. Dr. Larry H. Hollier was the dean, appointed in January 2004, at the time of Hurricane Katrina and he served as Dean and Chancellor for slightly less than two years when Dr. Steve Nelson was named Dean in September 2007. Dr. Hollier continues to serve as Chancellor of the LSUHSC New Orleans and he is the seventh permanent Chancellor for the New Orleans campus.

As Louisiana State University School of Medicine in New Orleans prepares to celebrate the 80 th Anniversary of its establishment, it continues to provide excellent undergraduate, graduate, and postgraduate medical education and patient care, and foster innovative biomedical research. The students, house officers, faculty and staff of the school not only survived the recent adverse events related to Hurricane Katrina, but they responded with renewed vigor and loyalty. The School of Medicine looks forward to the future with optimism, as it continues to have excellent applicants and graduates, supportive and dedicated faculty, strong alumni support, and a renewed campus.


SECTION I. INSTITUTIONAL SETTING

Part A: Key Quantitative Indicators

Please provide the following information, using your school’s copy of the Longitudinal Statistical Summary Report as the data source unless indicated otherwise.

a. Number of vacant department chair positions

2002-03 2003-04 2004-05 2005-06 2006-07 2007-08 2008-090 2 0 0 3 0 1

b. Total numbers of enrolled master’s and doctoral students in graduate programs in the biomedical sciences

2002-03 2003-04 2004-05 2005-06 2006-07 2007-08 2008-09Master’s 61 44 51 30 30 16 15

Doctoral 70 84 85 103 89 109 102

c. Total numbers of residents and clinical fellows on duty in ACGME-approved programs that are the responsibility of the medical school faculty

2002-03 2003-04 2004-05 2005-06* 2006-07 2007-08 2008-09Residents 518 514 525 545 426 439 464Fellows 94 76 110 94 49 57 77

* The institution lost about 110 trainees due to Hurricane Katrina during this year.

d. Percentage of graduating students who participated in a research project with a faculty member (source: AAMC Graduation Questionnaire)

2002-03 2003-04 2004-05 2005-06 2006-07 2007-08 2008-0943.8 42.7 41.1 36.9 30.4 38.7 NA*

*March 19, 2009____________________________________________________________________________________


SECTION I. INSTITUTIONAL SETTING

Part B: Narrative Data and Tables

IS-1. Each medical school must engage in a planning process that sets the direction for the institution and results in measurable outcomes.

To assure ongoing vitality and successful adaptation to the rapidly changing environment of academic medicine, schools need to establish periodic or cyclical institutional planning processes and activities. Planning efforts that have proven successful in medical schools and other professional or business milieus typically involve the definition and periodic reassessment of both short-term and long-range goals for the successful accomplishment of institutional missions. By framing goals in terms of measurable outcomes wherever circumstances permit, a school can more readily track progress toward their achievement. The manner in which a school engages in institutional planning will vary according to available resources and local circumstances, but all schools should be able to document their vision, mission, and goals; evidence indicating their achievement; and strategies for periodic or ongoing assessment of successes and unmet challenges. __________________________________________________________________________________

a. Provide a brief statement of the mission and goals of the medical school. When were these last reviewed?

Louisiana State University School of Medicine - New Orleans trains physicians and scientists in health care disciplines. The Medical School strives for excellence in medical education, research, and service through the following objectives:

Medical Education Mission ObjectivesThe undergraduate curriculum contains programs of study that enable students to become competent, caring physicians who can function in any healthcare system, continue self education, and appreciate and evaluate medical research. Graduate Medical Education programs and their support are important components of the educational mission. Graduates of specialty training programs will be skilled and knowledgeable in their chosen discipline and able to assume the responsibilities of a practicing physician. Training programs of the school assess and adjust to changing physician work force needs of the state.

Research Mission ObjectivesMedical education and research are related pursuits. Academic excellence in research heightens the intellectual atmosphere, develops new knowledge, and transmits current information for the benefit of all constituencies. The Medical School provides adequate facilities for trainee and faculty research including support areas such as the library, animal care, and computer services. Long term planning and acquisition of research funds are vigorously pursued to ensure research growth.

Service Mission ObjectivesThe school provides a model of excellence in public and private medical care and community oriented programs. The school remains responsive to changing health care systems and trends. Patient care activities are important to all school missions. Personal practice supports and maintains the clinical skills of faculty and expands opportunities for undergraduate and graduate teaching and research. The school develops community outreach programs that provide educational and service opportunities and enhance the quality of life of constituent communities.


The most recent comprehensive review was December, 2008

b. Provide an executive summary of the current medical school strategic plan, if any.

Consistent with its mission, and building on its historical role and traditional strengths, the LSUHSC School of Medicine - New Orleans strives to be a regional and national leader, recognized for its commitment to excellence and its passion for innovation, and defined by:

A competency-based approach to medical education that links undergraduate, graduate and continuing education in an integrated statewide system that blends modern technology with hands-on learning experiences and draws upon the strengths of regional partners to create a center of educational excellence that contributes to the recruitment and retention of physicians, representative of the diversity of our communities, well-prepared for practice in the State of Louisiana.

A research enterprise that fosters collaboration across disciplines, spans the continuum from basic science to the bedside, and promotes the discovery and application of new scientific and clinical knowledge, with an emphasis on addressing the health care issues and challenges that are of greatest import to the citizens of Louisiana.

An approach to patient care that is characterized by the existence of a fully integrated multi-specialty academic group practice that excels as a regional referral resource for complex tertiary care and demonstrates an ongoing commitment to improvement of the health status of citizens of Louisiana through the provision of care that is accessible, patient-centered, quality-focused and safety-oriented.

A strong commitment to diversity and community outreach that builds on, leverages and promotes the school’s patient care, research and educational strengths by seeking partnerships with city, state and regional groups and organizations, both public and private, to develop programs that benefit the citizens of Louisiana.

The “Overarching Goals” listed below serve as the core components that are requisite to fulfilling the goals of the Strategic Plan.

Promote excellence and innovation in all School of Medicine educational programs Foster a culture of academic and investigative excellence Structure existing and new clinical programs to fulfill short and long term goals while

strategically positioning SOM and LSU HealthCare Network for the completion of new University Hospital

Align goals and missions of core clinical entities Develop a cohesive mechanism for faculty orientation, development, and evaluation, including

those for SOM leadership Establish a clear and standardized process for annual reporting and Periodic Academic Unit

Review Refine budget principles for resource allocation, particularly as they relate to educational and

clinical programs


Promote diversity and expand community outreach programs, building in large part on existing relationships with our strategic partners (School of Public Health and Southeast Louisiana Area Health Education Center and others)

Enhance electronic web-based tools for all School operations Better communicate internally and externally on all SOM activities and those of its support

organizations

c. Date of most recent review or revision of the strategic plan:

December, 2008

d. How often is the plan reviewed or revised?

The last time that the School of Medicine developed a comprehensive strategic plan was in 1987, and this resulted in a long-range plan for the years 1988-1992. Subsequent to this, a Research Strategic Plan was developed in June/July of 1999 (which included a retreat), and this was followed up by the generation of another Research Strategic Plan (with associated retreat) in January, 2001. These latter two plans dealt only with research issues (both basic and clinical science). Strategic planning for the medical school curriculum was undertaken in 2000, and the curriculum was dramatically revised and renewed as a consequence of the retreat, its recommendations, and their implementation. A focused retreat and strategic planning for the clinical operation was undertaken in 2001. Plans are for comprehensive strategic planning to be undertaken at least every five years; however, updating and review of implementation of the strategic plan is planned at shorter intervals.

e. Briefly summarize or outline the planning process, including the main participants and the names or titles of individuals or groups whose approval is required to finalize the plan.

Under the direction of Dean Nelson, Associate Dean Janis Letourneau announced plans for the School of Medicine Strategic Planning Retreat on May 5, 2008. Invited participants included individuals identified as leaders from across the LSUHSC School of Medicine-New Orleans and several of its affiliated organizations. This group included Basic Science Department Heads, Clinical Science Department Heads, Center Directors, Associate and Assistant Deans, and selected faculty at various levels of appointment and rank who had demonstrated certain skills valuable to the planning process and a dedication and loyalty to the goals and success of the School of Medicine and LSUHSC. Other invitees included community and hospital partners, alumni, residents, and students. The retreat was held on June 7, 2008, and over 70 individuals attended the retreat. Alan Burgener, MHA, helped to facilitate the retreat and served as a key consultant. Institutional leadership personnel involved in facilitating the retreat were:

Steve Nelson, MD (Dean, School of Medicine)Janis G. Letourneau, MD (Associate Dean for Faculty and Institutional Affairs)Wayne Backes, PhD (Associate Dean for Research)Keith Schroth, MBA (Associate Dean for Fiscal Affairs)

During the retreat, the following areas were identified for development in the strategic plan, and, subsequently, workgroups were formed to develop the core priorities and goals defined in each of the following areas:


The names of the workgroup leaders are given in parentheses:

Educational Enhancement (Richard DiCarlo, MD) Research Infrastructure and Core Facilities (Alistair Ramsay, PhD) Community Outreach and Engagement (Robert Maupin, MD) Faculty Development and Mentoring (Peter Winsauer, PhD) Clinical Centers of Excellence (Christopher Baker, MD) Communication Strategies (Patricia Molina, MD, PhD)

The workgroup leaders met with Dean Nelson and Associate Dean Letourneau, along with additional senior leadership within the SOM and members of the administration on July 9, 2008, to review the specific work group charges, define expectations and set working timelines. Over 100 faculty members, strategic partners in health care and in the community, alumni, house officers, and students participated actively in the Work Groups, which met frequently to satisfy a demanding deadline. The faculty Work Group members were broadly representative of the school, incorporating the array of basic and clinical science disciplines, academic ranks and tracks, geographic site of activity, and specialized expertise or interest. The composition of the Work Groups reflected the diversity of the school and included elected Faculty Assembly representatives.

Formal recommendations on strategic initiatives, focused on the previously mentioned Work Group charges, were made to the Dean and abstracted into an integrated comprehensive plan. The plan is structured around ten broad overarching goals (see above) that reflect the traditional elements of activities within a School of Medicine - education, research, clinical service, and community service and outreach. Specific initiatives are outlined for each of the ten goals.

The roster of Strategic Work Group Committee Contributors is found in the attached appendix.

Finalization of the Strategic Plan document requires the approval of the Chancellor.


IS-2. A medical school should be, or be part of, a not-for profit institution legally authorized under applicable law to provide medical education leading to the MD degree. ___________________________________________________________________________________

a. Year of initial chartering: 1877

b. Type of charter (check one):

X Not-for-profitCommercial, for profit


IS-3. If not a component of a regionally accredited institution, a U.S. medical school must achieve institutional accreditation from the appropriate regional accrediting body.

The LCME is recognized by the U.S. Department of Education as an accrediting agency for the educational programs, more specifically for the accreditation of medical education programs leading to the M.D. degree. Because the LCME is not recognized as an institutional accrediting agency, it lacks standing to accredit stand-alone medical schools as institutions of higher education.

Institutional accreditation is granted by a regional accrediting agency, and is required to qualify for federal financial assistance programs authorized under Title IV of the Higher Education Act. Some regional accrediting bodies grant “pre-accreditation” as a first step to achieving full accreditation. In such circumstances the attainment of pre-accreditation status would meet the requirements of this standard.

___________________________________________________________________________________

a. Regional accrediting body (check one):

Middle States Association of Colleges and Schools

New England Association of Colleges and Schools

North Central Association of Colleges and Schools

Northwest Association of Schools and CollegesX Southern Association of Colleges and Schools

Western Association of Schools and Colleges

b. Current institutional accreditation status:

Accredited

c. Year of next regional accreditation survey:

2015

Documentation for the accreditation status of LSUHSC can be found at:http://www.sacscoc.org/details.asp?instid=44400


http://www.sacscoc.org/details.asp?instid=44400

IS- 4. The manner in which the medical school is organized, including the responsibilities and privileges of administrative officers, faculty, students and committees must be promulgated in medical school or university bylaws. ___________________________________________________________________________________

a. Provide a copy of the faculty bylaws that apply to the medical school, or the URL of the web site where they can be viewed.

The School of Medicine faculty does not have its own specific set of bylaws. Louisiana State University Health Sciences Center in New Orleans (LSUHSC-NO) is part of the Louisiana State System. Thus the Board of Supervisors of Louisiana State University and Agricultural and Mechanical College serves as the Management Board for LSUHSC-NO. The Bylaws and Regulations of the LSU Board of Supervisors can be viewed at www.lsusystem.edu/policies/bylaws_regulations/ or www.lsuhsc.edu/no/Administration/bylaws/. Of particular pertinence to the medical school faculty is Article VII (Rights, Duties and Responsibilities of Principal Administrative Officers of the University System) and Chapter II (Appointments, Promotions and Tenure). The other documents that define the framework for the activities of the LSUHSC-NO faculty are the following: the LSUHSC-NO Faculty Senate Constitution and Bylaws (www.lsuhsc.edu/no/schools/facultysenate/), the LSUHSC-NO School of Medicine Faculty Assembly Bylaws (www.medschool.lsuhsc.edu/faculty_assembly/bylaws.aspx), the LSU System Permanent Memoranda (www.lsuhsc.edu/no/administration/pm/) , the LSUHSC-NO Faculty Handbook (www.lsuhsc.edu/no/administration/academic/FacultyHandbook.pdf) and the LSUHSC-NO Chancellor’s Memoranda (www.lsuhsc.edu/no/administration/cm/).

b. Date of the most recent bylaws revision:

October 2, 2008

The most recent revision of the Bylaws and Regulations of the LSU Board of Supervisors was made on October 2, 2008. The LSUHSC-NO Faculty Senate Constitution and Bylaws were last revised in August, 2008, and the last revision of the LSUHSC-NO School of Medicine Faculty Assembly Bylaws was on April 10, 2003.

c. Briefly describe how the bylaws are made available to the faculty.

As stated above, the LSU System Board of Supervisors Bylaws and Regulations and Permanent Memoranda, the Bylaws of the LSUHSC Faculty Senate and the School of Medicine Faculty Assembly, the LSUHSC-NO Faculty Handbook, and the Chancellor’s Memoranda are all easily accessible on component websites within the main LSU website. Faculty may also keep abreast of all updates made to the Bylaws and Regulations, LSUHSC-NO Chancellor’s Memoranda and LSU System Permanent Memoranda by an email subscription sign up service, details of which are given in the Faculty Handbook.


http://www.lsuhsc.edu/no/administration/cm/

http://www.lsuhsc.edu/no/administration/academic/FacultyHandbook.pdf

http://www.lsuhsc.edu/no/administration/pm/

http://www.medschool.lsuhsc.edu/faculty_assembly/bylaws.aspx

http://www.lsuhsc.edu/no/schools/facultysenate/

http://www.lsuhsc.edu/no/Administration/bylaws/

http://www.lsusystem.edu/policies/bylaws_regulations/

IS- 5. The governing board responsible for oversight of the medical school must have and follow formal policies and procedures to avoid the impact of conflicts of interest of members in the operation of the school, its associated hospitals, or any related enterprises.

There must be formal policies and procedures to avoid the impact of conflicts of interest, such as the requirement that a board member recuse him/herself from any discussion or vote relating to a matter where there is a potential for a conflict of interest to exist. The school also must provide evidence (for example, from board minutes, annual signed disclosure statements from board members) that these policies and procedures actually are being followed. Some conflicts related to personal or pecuniary interests in the operation of the school may be so pervasive as to preclude service on the governing board.

The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College is established by Article 8, Section 7 of the Louisiana Constitution. It is a constitutionally empowered board granted the authority and responsibility to “supervise and manage the institutions, statewide agricultural programs, and other programs administered through its system.” The Board of Supervisors is the governing authority of the Louisiana State University Health Sciences Center and the LSUHSC School of Medicine – New Orleans. Formal Conflict of Interest policies for the LSU Board of Supervisors are in place and are referenced in IS 6e.


IS-6. Terms of governing board members should be overlapping and sufficiently long to permit them to gain an understanding of the programs of the medical school.

_____________________________________________________________

a. Check any units for which the governing board is directly responsible:

X Parent UniversityX Health Science CenterX Medical SchoolX Other (describe below)*

* LSU Health Care Services Division (the state-wide system of public hospitals, most of which support educational programs)

b. Year of board chair’s appointment and length of board chair term(s) of office

Appointed -August 29, 2008; Term – One year

Mr. James P. Roy (Chairman)P.O. Box 3668Lafayette, LA 70502(337) [email protected]

Mr. Roy represents the 7th Congressional District, and his term of service on the Board itself ends on June 1, 2010; he is chair of the Board until August 29, 2009. He is an attorney.

d. Summarize the procedure for appointment and renewal of university or health science center board members, including the chair. Describe the length of members’ terms, the number of times that a member can be reappointed, and the staggering of appointments, if appropriate.

The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College is established by Article 8, Section 7 of the Louisiana Constitution. It is a constitutionally empowered board granted the authority and responsibility to “supervise and manage institutions, statewide agricultural programs, and other programs administered through its system.” The constitution provides that the membership of the board is composed of two members from each congressional district and one member from the state at large, appointed by the governor with confirmation of the Louisiana Senate. Those members serve six-year terms, which are staggered; Board members service is limited to two consecutive six-year terms. In addition, a student member is selected to serve a one year term.

e. Provide copies of policies and procedures intended to prevent or address conflicts of interest among board members (including recusal from discussions or decisions if a potential conflict occurs), and strategies for dealing with actual or perceived conflicts of interest if they arise. Provide examples to illustrate that these policies are being followed.

Formal policies and procedures have been established to avoid the impact of conflicts of interest. For example, there is a requirement that a board member recuses him/herself from any discussion or vote relating to a matter where there is a potential for a conflict of interest to exist. The Conflict of Interest policy for the Board of Supervisors is attached.


mailto:[email protected]

(ADD TO APPENDIX)

f. If the medical school is governed by its own board of trustees, or is overseen directly by a subcommittee of the university or health science center board, provide a separate description for appointment and renewal of its members, conflict of interest policies, and strategies for addressing actual or perceived conflicts of interest.

Not applicable.


IS- 7. Administrative officers and members of a medical school faculty must be appointed by, or on the authority of, the governing board of the medical school or its parent university. ___________________________________________________________________________________

Briefly describe the role of the governing board in the appointment of administrative officers and faculty of the medical school.

The following web link (http://www.lsuhsc.edu/no/administration/pm/pm-69.aspx) and a section of the LSU Bylaws (Section 2-5.1) deal with the LSU System policies for LSU Board of Supervisors authority and its ability to delegate authority to the President or Chancellor.

As stated in recently revised Permanent Memorandum #69 (January 8, 2009), certain personnel actions must be approved by the Board (Section A) with salary threshold compensation modifications for the two LSUHSC campuses. As is relevant to the School of Medicine, the appointment of the dean and amendments to, or extensions of, appointment agreements and increases or decreases in compensation require Board approval. Other administrative appointments in the Dean’s Office generally require approval by the LSU President’s Office.

Many of the School of Medicine faculty appointments, particularly to senior basic science and to highly-paid clinical science faculty members, require Board approval because of the compensation level that is proposed. At lower proposed compensation levels the Board delegates some appointment authority to the President and others to the Chancellor with compensation levels falling within a range subject to the President’s review and approval. The LSU Board of Supervisors encourages the use of standard templates for offers to faculty (see Permanent Memorandum #69), and deviations from the normal terms also require review and approval by the LSU System Office or LSU General Counsel. The School of Medicine has used standard letters of offer for many years, and the templates for faculty appointments are posted on the School of Medicine Faculty Affairs web site.

All personnel actions for administrative officers and faculty are regularly reported to the President and the Board in a format that is set by the President after consultation with the Board. In recent years, and particularly with the issuance of Permanent Memorandum #69, the School of Medicine has received more detailed directives by the Board of Supervisors and the President on matters relating to appointment of administrative officers and faculty members.


http://www.lsuhsc.edu/no/administration/pm/pm-69.aspx

IS-8. The chief official of the medical school, who usually holds the title “dean,” must have ready access to the university president or other university official charged with final responsibility for the school, and to other university officials as are necessary to fulfill the responsibilities of the dean’s office.

The Office of the Dean is currently occupied by Steve Nelson, MD. The Dean is responsible for all aspects of operations of the School of Medicine. The Dean reports to the Chancellor of LSU Health Sciences Center – New Orleans, Larry H. Hollier, MD. The Chancellor is the Chief Executive Officer for the LSUHSC campus, responsible for the operations of all six of the component professional schools. The Chancellor reports to the President of the LSU System, John Lombardi, PhD.

Fred Cerise, MD, the Vice President for Health Affairs, also reports to the President of the LSU System and serves as a liaison between the LSU Health Sciences Center campuses, the LSU Health Care Services Division (the state system of seven public “Charity” hospitals operated by LSU), and the two LSU Schools of Medicine. The lines of reporting for these officials, and their relationship with other administrative bodies, is detailed in the organizational chart provided in the Appendix.

Suffice it to say, the Dean has direct and ready access to the Chancellor. He also is able to talk and meet with Dr. Cerise (Vice President) and Dr. Lombardi (President) as needed.


IS-9. There must be clear understanding of the authority and responsibility for medical school matters among the vice president for health affairs, the dean of the medical school, the faculty, and the directors of the other components of the medical center and university. ___________________________________________________________________________________

a. Provide a position description for the dean and, if applicable, the vice president for health affairs or equivalent.

INSERT PD for DEAN The Dean of the School of Medicine is appointed by, and serves at the pleasure of, the Chancellor of the LSU Health Sciences Center and the LSU Board of Supervisors. This appointment requires approval of the Board of Supervisors. The Dean reports to the Chancellor, who, as mentioned earlier, is the Chief Executive Officer for LSUHSC – New Orleans and its six component professional schools. Through multiple avenues of communication, the faculty clearly understands the dean’s authority and responsibility for the School of Medicine operations; these lines of communication include, but are not limited to, Administrative Council, Faculty Asembly,and General Faculty and department faculty meetings.

INSERT PD for CHANCELLOR The Dean is accountable for all educational, research, and service programs of the School of Medicine, as well as for its financial affairs. Largely, his activities are reviewed by the Chancellor, Dr. Hollier. While the dean’s role is primarily, but not exclusively, internal to the school, the chancellor’s role is both internal and external, being the principal spokesperson for the LSUHSC campus to civic and state officials and to private partners. Both the Dean and Chancellor have, as mentioned earlier, access to the Vice President for Health Affairs and Medical Education and to the President.

INSERT PD for VP The Vice President serves as a liaison and a resource for the Dean and the Chancellor in coordinating the complex and inter-related programs of the school and campus more broadly. The Vice President, Dr. Cerise, is involved with strategic planning and development of performance targets, develops health care delivery and education policies, and he provides leadership for the development of annual budgets and long range financial planning for both LSUHSC campuses and the LSU Health Care Services Division. The Vice President provides leadership and guidance to the President of the LSU System and the LSU Board of Supervisors; he works collaboratively with all LSU programs related to health care delivery and health sciences education; and, he serves as a liaison between the Chancellors and the President.

b. Supply a chart showing the relationships among the medical school and university administration, other schools and colleges, institutes, centers, etc. Include, if appropriate, the reporting relationships for the director of any teaching hospitals owned or operated by the medical school or university and for the medical faculty practice plan. (ADD TOO for SOM, LSU and LSUHSC)

As discussed earlier, the Chief Executive Officer (Michael Butler, MD, MHA, Interim CEO) for LSU Health Care Services Division (the seven state “public” hospitals operated by LSU or HCSD) reports directly to the President; several of the HCSD hospitals support undergraduate and graduate education or service programs for the School of Medicine, including MCLNO (Interim LSU Public Hospital), Earl K. Long Medical Center in Baton Rouge, University Medical Center in Lafayette, Bogalusa Medical Center, and Lallie Kemp Medical Center in Independence. Dr. Butler, like the LSUHSC Chancellors, also works collaboratively with the Vice President for Health Affairs and Medical Education as noted earlier.


The Chief Executive Officer, Frank Opelka, MD, of the LSU HealthCare Network, a not-for-profit support organization for the LSUHSC – New Orleans and the medical faculty group practice, is the Vice Chancellor for Clinical Affairs, reporting to Dr. Hollier, as Chancellor, and to Dr. Nelson, as Dean. The Chief Executive Officer of the HealthCare Network is also accountable to the Board of Directors of the organization. The Chief Medical Officer of the HealthCare Network is the Associate Dean for Clinical Affairs, Thomas Nolan, MD, MBA, who reports to the Dean and to the Chief Executive Officer for the organization.


IS-10. The dean must be qualified by education and experience to provide leadership in medical education, scholarly activity, and care of patients. ___________________________________________________________________________________

Include here a brief resume of the dean’s academic and administrative experience. In the Appendix, provide a full CV.

Steve Nelson, MD, Dean of the School of Medicine, is highly regarded bythe faculty and students for his accomplishments as teacher, clinician, and researcher. He has spent the majority of his academic career at the LSUHSC School of Medicine. He is the John H. Seabury Professor of Medicine, and Professor of Pediatrics, Physiology, and Microbiology and Immunology. He is an active researcher with long-standing grant support from the National Institutes of Health and other funding agencies. He was appointed Dean in September 2007 after a national search conducted by a committee representative of the LSUHSC campus.

Since 1984 Dr. Nelson has been an active staff member (Pulmonary/Critical Care) at MCLNO and at other facilities in the New Orleans Area. His major clinical interests include pneumonia, adult cystic fibrosis, and sepsis. Dr. Nelson has served on our faculty in multiple roles including that of Section Chief of Pulmonary/Critical Care Medicine and Vice Chair in the Department of Medicine. Most notably, he is the Director of the Alcohol Research Center, a large interdepartmental project funded by the National Institute on Alcohol Abuse and Alcoholism with an annual budget of $2M. His research interests are primarily directed at understanding normal pulmonary host defense mechanisms and determining the potential of biological response modifiers for prevention and treatment of pulmonary infections. He has obtained recognition for exemplary teaching of medical students, residents, and fellows. He serves on the editorial board of several journals, is a member of the Bests Doctors in America, and is the author of 196 peer reviewed publications and 30 book chapters. The complete curriculm vitae for Dr. Nelson is provided in the Appendix.

DegreeMD – McGill University, Montreal, Canada, 1978

Internship:Medicine, Johns Hopkins Hospital, Baltimore, Maryland, 1978-1979

Residency:Medicine, Johns Hopkins Hospital, Baltimore, Maryland, 1979-1981

Fellowships:Clinical Fellowship in Pulmonary Medicine, Johns Hopkins Hospital, Baltimore, Maryland, 1981-1982Research Fellowship in Pulmonary Medicine, Johns Hopkins Hospital, Baltimore, Maryland, 1982-1984Fellowship in Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins Hospital, Baltimore, Maryland, 1982-1984

Board Certifications:Licentiate, Medical Council of Canada -l978Diplomate, National Board of Medical Examiners - 1979Diplomate, American Board of Internal Medicine - 1981FLEX - 1984


Diplomate, American Board of Internal Medicine, Pulmonary Disease - 1986Diplomate, American Board of Internal Medicine, Critical Care Medicine - 1987

Medical Licensure:Maryland, 1981, D26487Louisiana, 1984, 06586R


IS-11. The medical school administration should include such associate or assistant deans, department chairs, leaders of other organizational units, and staff as are necessary to accomplish the missions of the medical school.

There should not be excessive turnover or long-standing vacancies in medical school leadership. Medical school leaders include the dean, vice/associate deans, department chairs, and others where a vacancy could negatively impact institutional stability, especially planning for or implementing the educational program. Areas that commonly require administrative support include admissions, student affairs, academic affairs, faculty affairs, graduate education, continuing education, hospital relationships, research, business and planning, and fund raising.

___________________________________________________________________________________

a. Attach a chart showing the organizational structure of the dean’s office.

The Dean’s Office Organizational chart is attached and is available to the faculty and students on the Dean’s Office website: http://www.medschool.lsuhsc.edu/administration/docs/deans_office_chart.pdf.

b. List the percent of effort which each associate and assistant dean contributes to the administrative support of the medical school and for each, indicate his/her date of appointment to the administrative role. Indicate if any associate/assistant dean position is being filled on an interim basis.

There are currently no associate/assistant dean positions that are filled on an interim basis.

Position Name Appt % EffortDean Steve Nelson, MD 9/18/2007 100%Assoc Dean for Fac & Inst Affairs Janis Letourneau, MD 6/1/1996 100%Dir of Faculty Development Paula Gregory, PhD 2/01/2009 30%Assoc Dean for Student Affairs Joseph Delcarpio, PhD 1/1/2006 100%Assist Dean for Student Affairs Fred Lopez, MD 7/1/01 80%Assoc Dean for Research Wayne Backes, PhD 10/1/2001 50%Dir of Research Development Jean Jacob, PhD 11/1/2008 30%Assoc Dean of Admissions Samuel McClugage, PhD 7/1/2000 50%Assoc Dean for Acad Affairs Charles Hilton, MD 7/1/2000 100%Assist Dean for Acad Affairs Richard DiCarlo, MD 7/1/2002 100%Dir of Basic Science Curriculum Michael Levitzky, PhD 2/10/1998 33%Dir of Clinical Science Curriculum Robin English, MD 11/1/2008 50%Director of OMERAD Sheila Chauvin, PhD 10/1/2002 100%Assoc Dean for Fiscal Affairs Keith Schroth, MBA 6/20/2003 100%Assoc Dean for Clinical Affairs Tom Nolan, MD, MBA 11/1/2007 50%Assoc Dean for Hlth Care Qual & Safety Dwayne Thomas, MD 12/5/2008 100%Assoc Dean for Alumni Affairs Cathi Fontenot, MD 1/1/2009 70%Assoc Dean for Comm & Minority Hlth Ed Edward Helm, MD, MHA 1/1/1996 80%Assoc Dean of Baton Rouge Affairs W. Chapman Lee, MD 10/1/2007 100%Assist Dean of VA Affairs Paul Rosenfield, MD 11/1/1996 GratisAssistant Dean at Children’s Hospital Alan Robson, MD ??? GratisAssoc Dean of Lafayette Affairs James Falterman, MD 10/1/2007 90%


jletou, 04/03/09,

We will also need to add as appendix

http://www.medschool.lsuhsc.edu/administration/docs/deans_office_chart.pdf

c. Indicate the term of appointment for department chairs and the number of times that appointment can be renewed.

Department chairs are appointed for an indefinite period.

d. Indicate the date of appointment for each currently sitting department chair.

Department Name Appt DateCell Biology & Anatomy Samuel McClugage, PhD 9/1/2007Biochemistry & Molecular Biology Arthur Haas, PhD 7/15/2004Genetics Jay K. Kolls, MD 1/1/2009Microbiology, Immunology & Parasitology Ronald Luftig, PhD 9/1/1983Pharmacology & Experimental Therapeutics Kurt Varner, PhD (interim) 12/1/2006Physiology Patricia Molina, MD, PhD 9/1/2008Anesthesiology Alan Kaye, MD, PhD 1/31/2005Dermatology Lee Nesbitt, MD 10/26/2004Family Medicine Kim LeBlanc, MD, PhD 9/1/2002Internal Medicine Charles Sanders, MD 7/1/1989Neurology John England, MD 11/19/2007Neurosugery Frank Culicchia, MD 6/19/2006Obstetrics and Gynecology Thomas Nolan, MD, MBA 8/1/2002Ophthalmology Donald Bergsma, MD 7/1/2003Orthopedics Andrew King, MBBCh 7/1/2008Otorhinolaryngology Daniel Nuss, MD 12/2/2000Pathology Jack Strong, MD 4/1/1966Pediatrics Ricardo Sorensen, MD 7/1/2000Psychiatry Howard Osofsky, MD, PhD 7/1/1986Radiology Leonard Bok, MD, JD, MBA 10/1/2006Surgery Christopher Baker, MD 12/1/2007Urology J. Christian Winters, MD 11/1/2006Stanley S. Scott Cancer Center Augusto Ochoa, MD 11/1/2007Gene Therapy Program Alistair Ramsay, PhD 7/1/2005Neurosciences Center Nicolas Bazan, MD, PhD 7/1/1989

e. List the departments without a permanent chair and the date when the last permanent chair left office Describe the status and timelines of recruitments to fill vacant chair positions.

Currently, there is only one Department (Pharmacology and Experimental Therapeutics) without a permanent Department Head. The Department of Pharmacology has had an interim head since the resignation of the permanent head in December 2006. Dr. Nelson, in concert with the department, decided to suspend the pharmacology search for a short period of time due to the stability of the department.

However, the Dean is conducting searches to replace the permanent Department Heads in the Departments of Ophthalmology and Pathology; it is hoped that these positions will be filled by July 2009 or soon thereafter. With these latter searches no interim heads have been named because of the anticipated speed of the search and because both department heads are comfortable remaining in their seats while the searches are underway.


Since beginning as Dean, Dr. Nelson has named two permanent Department Heads in basic sciences, in Genetics and in Physiology, both vacated due to retirements; he also has filled the Department Head position in Orthopaedics, vacated by a disability-retirement.

Each department head search is conducted on a national basis with the committee comprised of campus leaders and senior faculty members, and often with one outside consultant (if an endowed chair is being considered as part of the recruitment package), with oversight from the Dean’s Office.

The search committee for Pathology includes an outside consultant from New Mexico, Mary Lipscomb, MD, who satisfies the Louisiana Board of Regents requirement for an outside expert on the search committee for endowed chairs. The advertisements for this position were posted in late 2008 and early 2009. To date, there have been approximately 10 applications, and three excellent candidates have already been interviewed; a fourth candidate will be interviewed in March, 2009. Second visits for the top candidates are anticipated to be in April, 2009, with an incumbent starting by July, 2009. The Ophthalmology Department Head position was advertised beginning in October, 2008 and more than a dozen applicants responded. Of those, two have been invited for visits in March and April, with a new head hoped to be in place by Summer, 2009. This search committee will use an outside expert to evaluate short-listed candidates, again fulfilling the Regents requirement for selection of an incumbent for an endowed chair.

f. Briefly describe how, how often, and by whom the performance of chairs is reviewed.

The Dean formally evaluates the department heads and center directors at least oncea year; however, the Dean schedules regular detailed reviews of departmental operations at least twice a year. During the formal annual review, the Administrative Annual Review form (available on the School of Medicine Faculty Affairs website ) is submitted in conjunction with the chair’s curriculum vitae.

g. Briefly describe the budgetary authority of department chairs, and the sources of funding for departmental budgets.

The School of Medicine uses a budget allocation methodology that follows general Mission Based Budgeting principles. The departments receive a budget allocation using a few fundamental formulaic calculations. The department heads (and center and program directors) have delegated budgetary authority within the limits or allocations established by the Dean’s Office. The Dean has ultimate authority and accountability for the School of Medicine budget; the Dean receives recommendations and advice from the Associate Dean for Fiscal Affairs, who exercises oversight over all the departmental expenditures.

In the basic science departments, Mission Based Budgeting (MBB) guides the funding allocation for teaching based directly upon the amount of teaching required for the educational programs of the department. MBB also formulaically allocates funding for part of the salaries of research faculty; it is anticipated that research grants support approximately 50% of the salaries for individual research faculty members. Should a faculty member cover more than 50% of his/her compensation through salary on grants, the department benefits financially from the additional salary “offset”. MBB also allows for formula-driven funding allocations for administrative support for the department head and faculty and for basic academic expenses (travel, dues) and for 50% of the department head salary and benefits. Basic Science departments can build reserves through the generation of indirect costs on grants, a portion of which accrues to each department, and offset of salary for research faculty funded through extramural programs. Department Heads have broad discretionary use of reserve funds in


jletou, 04/03/09,

Add web link and append the form to the self study.

accordance with school, campus and university policies. Basic science departments can also request funding from the dean to recruit new investigators (salary and start up) with the hope that extramural funding will be successfully sought to cover costs of future research.

Like the basic science departments, the clinical science departments receive a formula-driven budget allocation based on the number of full-time equivalent faculty members required for their educational programs, the number of research faculty involved in funded investigational work, the total number of faculty full-time equivalents and the attendant administrative and academic expenses, the Department Head compensation, and the number of training programs in the department. Additionally, clinical science departments generate revenue from the faculty physician practice (the LSU HealthCare Network) and through contracts, established to formalize arrangements for professional services, medical direction, and resident supervision to private and governmental entities. As is the case with basic science departments, clinical science Department Heads can request funding to support the recruitment of investigators and the recruitment of clinicians. Dean’s commitments to clinical science departments for faculty recruitment are made with the expectation that individual faculty will generate sufficient revenue (through extramural research programs or through clinical collections or contracts) to support their activities. Clinical departments can build reserves through their portion of indirect costs generated from grant revenues, from salary on grants offsets, and cost savings or departmental “taxes” added into clinical contracts during negotiations. Clinical science Department Heads have broad discretionary use of reserve funds in accordance with school, campus and university policies.

See also Part A, item (a.) in this section of the database.


IS-12. A medical school should be a component of a university offering other graduate and professional degree programs that contribute to the academic environment of the medical school.

There should be regular and formal review of all graduate and professional programs in which medical school faculty participate, to foster adherence to high standards of quality in education, research, and scholarship, and to facilitate the progress and achievement of the trainees.

___________________________________________________________________________________

a. Numbers of students enrolled in master’s and doctoral programs taught by medical school faculty.

Department or Program Master’s Students Doctoral StudentsBiostatistics* 4 5Biochemistry and Molecular Biology

0 13

Cell Biology and Anatomy 0 4Human Genetics 0 9Microbiology, Immunology and Parasitology

4 18

Neuroscience 1 22Oral Biology 5 NAPathology 0 1Pharmacology and Experimental Therapeutics

1 20

Physiology 0 10*Largely a program of the School of Public Health

b. Are there university or medical school policies that require regular review of graduate education programs (master’s, doctoral)? If so, include a copy of the policy or related documents in the appendix.

All graduate programs in the state of Louisiana are reviewed periodically by the Louisiana Board of Regents – the regulatory unit for higher education in the state.

http://www.regents.state.la.us/Academic/PP/Policies/2-6.html

“Academic Affairs Policy 2.06Board of Regents Reviews of Existing Academic Programs/Units

The Board of Regents will periodically review and evaluate program quality and productivity at all levels of higher education. Affected institutions will be required to participate in these reviews and evaluations. Interested persons will be given an opportunity to appear before the Board of Regents prior to decisions in each particular case.”

Programs with low completion rates are reviewed and if not successful, are terminated.

Within the LSU System, the LSU Health Sciences Center – New Orleans is accredited as an independent entity by the Southern Association of Colleges and Schools. During the accreditation process, the School of Graduate Studies is reviewed intensely because it is the only school that has no other accreditation process.


http://www.regents.state.la.us/Academic/PP/Policies/2-6.html

c. Describe the process used for review of doctoral programs in the biomedical sciences.

The doctoral programs are under the aegis of the seven basic science departments (Biochemistry and Molecular Biology; Cell Biology and Anatomy; Genetics; Microbiology, Immunology and Parasitology; Pathology; Pharmacology and Experimental Therapeutics; Physiology) and the Neuroscience Center. A new doctoral program in Biostatistics has recently been approved by the Board of Supervisors of the LSU System and the Board of Regents of the state. This doctoral program is administered through the School of Public Health but under the auspices of the School of Graduate Studies. The Dean of the School of Graduate Studies, who also serves as the Vice Chancellor for Academic Affairs, is ultimately responsible for review of doctoral programs. He is advised by the Graduate Advisory Council (GAC) which is made up of the graduate coordinators from each of the degree-granting programs and another faculty member who is appointed by the Department Head of each of the graduate programs. Thus, each doctoral degree-granting program has two representatives to the GAC. The Curriculum Committee of the GAC reviews requests for new courses and for changes in courses. Upon recommendation of the Curriculum Committee, the GAC approves both the courses offered in the curriculum and changes to the curriculum. The recommendation of the GAC is brought to the Dean of the School of Graduate Studies for final approval. The GAC also approves nominations of faculty to be members of the Graduate Faculty. Membership in the Graduate Faculty is required for faculty to be graduate student advisors for masters and doctoral degrees. Applications to the Graduate Faculty are reviewed by the Membership Committee of the GAC. Their recommendation is brought to the GAC whose approval is required prior to the approval by the Dean. The doctoral program for each individual student is overseen by the student’s Dissertation Committee which consists generally of four faculty members from the department and one member from another Department or another University. All must be members of the Graduate Faculty. The Committee members and the Department Head must sign their approval of both the Preliminary Exam and the Defense prior to approval by the Dean of the School of Graduate Studies. The office of the Dean of the School of Graduate Studies tracks students for timely completion of their doctoral training program.

See also Part A, item (b.) in this section of the database.


IS-12-A. Medical students should learn in clinical environments where graduate and continuing medical education programs are present.

In order to link medical student education to the later stages of the medical education continuum, medical students should spend time in settings where graduate and continuing medical education programs are present. It is expected that medical students will participate, where appropriate, in the activities associated with these programs. The graduate and continuing medical education programs at training sites where medical students are located should be accredited by the appropriate accrediting bodies.

___________________________________________________________________________________

a. For each clinical facility where one or more students take a required core clerkship (except ambulatory, community-based sites), mark a (+) if residents in ACGME-accredited programs are involved in medical student education in that clerkship at that site; place a (–) for any clerkships offered at that site where there is no resident participation.

Clinical FacilityName Fam. Med. Int. Med. Ob/Gyn Pediatrics Psychiatry Surgery

Ochsner-Kenner + + +MCLNO-LSU Interim Hospital(University) + + + +

Earl K. Long + + +UMC-Lafayette + + + - +Joe Taylor-Lafayette -Our Lady of the Lake-Baton Rouge +

West Jefferson +East Jefferson - -Baton Rouge General +

New Orleans Adolescent Hosp +

DePaul Campus (MCLNO) +

Ochsner-Jeff Hwy + +Childrens + +Bogalusa Medical Center +

Lake Charles +Touro +

b. If the medical school does not include a separate required clerkship in any of the above disciplines (for example, in the case of a longitudinal clinical track for some students), describe these students’ interactions with residents, including the residents’ specialties and the settings in which these interactions occur.

Not applicable


c. Provide the number of residents who are the responsibility of your faculty, by training program (Note: If the school operates geographically separate clinical campuses, provide a separate table for each campus):

Specialty of Training Program

PGY-1residents

Total Residents

Clinical Fellows(ACGME-approved

programs)

Clinical Fellows (Non-ACGME

approved programs)Dermatology 16Medicine / Dermatology 2 2Emergency Medicine 10 43Medicine/Emergency Med 2 9Family Medicine-Kenner 7 21Medicine-Categorical 10 35Medicine-Preliminary 9Medicine/Pediatrics 7 23Neurology 3 14Child Neurology 2Neurosurgery 7OB/GYN 7 28Ophthalmology 25Orthopaedics 4 20Otorhinolaryngology 3 14Pathology 2 7Pediatrics 17 56PM&R 6 21Psychiatry 10 29Child Psychiatry 6Surgery-Categorical 7 38Surgery-Preliminary 5 5Plastic Surgery 4Medicine-A/I 1Medicine-Cardiology 13Medicine-G/I 6Medicine-ID 5Medicine-Nephrology 6Medicine-Pulmonary 8Medicine-Rheumatology 2Neurology-Clinical Neurophysiology 1

Ophthalmology-Retina 3Orthopaedics-Pediatrics 1Otolaryngology-Fellow 1Pathology-Surgical 1Pediatrics-A/I 4Pediatrics –Endocrinology 3Pediatrics – GI 2Pediatrics-Hematology/ 4


OncologyPediatrics - Neonatology 3Pediatrics - Nephrology 1PM&R – Pain Medicine 3Surgery – Critical Care 2Surgery – Vascular 2

The residencies for Anesthesiology and Radiology were accredited for July 1, 2009.


PGY-1residents

Total Residents


programs)


approved programs)*Sponsored by LSU School of Medicine – New Orleans Family Medicine-Bogalusa 4 8


PGY-1residents

Total Residents


programs)


approved programs)*Sponsored by LSU School of Medicine – New OrleansFamily Medicine-Lake Charles 7 23


PGY-1residents

Total Residents


programs)


approved programs)*Sponsored as Earl K. Long Hospital - a separate sponsoring institution for ACGMEEKL-Emergency Medicine 15 41EKL-Int Medicine-Categorical 10 33EKL-Int Medicine-Preliminary 7EKL-OB/GYN 4


PGY-1residents

Total Residents


programs)


approved programs)*Sponsored as University Medicine Center-Lafayette - a separate sponsoring institution for ACGMEUMC-Family Medicine 8 24UMC-Family Medicine Geriatrics 1

UMC-Internal Medicine 9 27


d. Describe the mechanism used for oversight and coordination of graduate medical education, including evaluation and allocation of training positions. Note any programs currently on probation, as well as programs being substantially expanded or reduced in size.

The School of Medicine oversight of the graduate medical education training is done through the LSU Office of Graduate Medical Education with the Associate Dean for Academic Affairs as the leader. The oversight committee (Graduate Medical Education Committee) holds monthly meetings and follows a timeline of issues to be discussed at each meeting throughout the year to ensure that training programs are up to date on compliance and administrative issues regarding the education of residents. The Graduate Medical Education Committee is comprised of residency and fellowship program directors, chief residents and other residents, senior educators, and administrative staff. Some of its responsibilities are as follows.

Internal Program Reviews give the LSU Office of Graduate Medical Education an opportunity to evaluate the training programs at mid accreditation cycles to rectify any weakness or citations that may be seen in a program. The committee also reviews the materials developed in support of new residencies and fellowships before they are submitted to the respective Resident Review Committees. The committee develops policies and procedures and proposes acquisition and allocation of the many resources needed for compliance with ACGME Residency Review Committee requirements. The establishment, implementation, and refining of institutional policies for graduate medical education, including those involving discipline, due process, selection and promotion, are handled by the committee. The allocation of training positions is overseen by the Office of Graduate Medical Education and also approved by the ACGME. Programs participate in the NRMP – National Residency Matching Program.

e. For each accredited institution, provide the following information regarding ACGME Institutional Review of graduate medical education programs sponsored by the school or its major teaching hospital(s):

Date of Last ACGME Institutional Review Status Date of Next

Review

5/22/2008 (LSU SOM- N.O.) Continued Accreditation 11/2013

5/28/2008 (UMC-Lafayette) Continued Accreditation 10/2011

5/17/2005 (Earl K Long-B.R.) Continued Accreditation

Anticipated date 10/2009

f. If the medical school or its clinical affiliates are accredited by the ACCME to sponsor continuing medical education for physicians, indicate each program’s current accreditation status, length of accreditation granted, and year of the next accreditation review.

Program Sponsor Accred. Status Length of Accred. Term Year of Next Review

LSU School of Medicine, New Orleans ACCME Accreditation 6 years 11/2011


g. Describe how medical students have the opportunity to participate in continuing medical education programs. Is participation in any continuing medical education programs expected/required?

Students and residents are allowed to participate in competency based CME programs in our Learning Centers where applicable, and all students participate in various departmental Grand Rounds which have CME sponsorship by the school through the IPE. Participation requirements are handled on individual departmental levels.

See also Part A, item (c.) in this section of the database.


IS-13. The program of medical education leading to the MD degree must be conducted in an environment that fosters the intellectual challenge and spirit of inquiry appropriate to a community of scholars. ___________________________________________________________________________________

a. If not already described in the response to standard IS-1, briefly summarize institutional goals and priorities relating to research and scholarship.

These goals are taken directly from the recent Strategic Plan (2008).

Goal #1Promote excellence and innovation in all School of Medicine educational programs

o Enhance undergraduate education in context of LCME accreditation standards Assure comparability in educational opportunities across training sites

Conduct independent evaluations of clerkship experiences in New Orleans, Baton Rouge and Lafayette

Strengthen administrative relationships and support for clerkships in New Orleans, Baton Rouge and Lafayette

Develop comparable didactic (core curricular) experiences in New Orleans, Baton Rouge and Lafayette

Assess technical and space support for teaching activities in Baton Rouge and Lafayette and address deficiencies if identified

o Emphasize competency-based educational programs in curriculum objectives Incorporate ACGME core areas of competence into undergraduate and graduate

curriculao Introduce students and house officers to basic principles of clinical and translational

research integrating principles into preclinical courses, developing on-line basic science modules for required clerkships, and developing a Biomedical Sciences Course

o Establish data base of educational experiences and an Electronic Learner Portfolio project

Develop a consistent tracking method for required clinical experiences Centralize student and faculty evaluations and outcomes data Begin development of Electronic Learner Portfolio

o Enhance simulation programs in Student Learning Center and Center for Advanced Practice

Conduct comprehensive planning effort focused on Student Learning Center and Center for Advanced Practice

Strengthen operational model to ensure greater responsiveness to specialty-specific needs

Solidify designation as American College of Surgeons Comprehensive Education Institute

Consider creation of a Simulation Subcommittee to the Computer-Assisted Learning Curriculum Committee

Encourage scholarship in educational programs using simulation and competency-based curricular goals

Evaluate staffing mix and role definitions to assure optimal blend of technical/training support and those involved in content development

Assess feasibility of partnering with hospital training sites (especially HCSD facilities) to coordinate simulation-based educational efforts focused on patient care and outcomes (i.e. CMS designated “never events”)


Initiate faculty development in basic curriculum using simulation and case-based teaching

o Expand and strengthen Rural Scholars Track Assess full range of clinical (i.e. office-based primary care, nursing home, and

hospice or end-of-life care settings), didactic, and scholarly experiences, as well as associated settings, that would lead to a strong and distinctive Rural Scholars Track

Develop written curriculum and learning objectives to distinguish Rural Scholars Track from the remainder of the undergraduate curriculum

Formalize administrative support for program and expand training site opportunities

Review admissions recruitment strategies Increase exposure to primary care in curriculum

Goal #2 Foster a culture of academic and investigative excellence

o Enhance research capabilities of clinical departments and prioritize the recruitment of faculty and faculty leadership with translational research expertise

o Continue support for intramural research funding Continue Clinical Translational Research Initiative (LSUHSC Research Council) Expand scope of SOM Research Enhancement Programs

o Implement curricular changes emphasizing basic and translational research Expand research content in pre-clinical courses Develop semester course for clinical trainees (Biomedical Sciences Course)

o Support faculty through mentoring and research development programs Fill position of Director of Research Development

Assist departments and centers in developing faculty support in research efforts

Build mentoring programs for individual (junior) faculty through senior faculty, department heads, and program and center directors

Work with departments and centers to develop regular research programs (research or work in progress or grant-seeker sessions)

Coordinate multiple seminar series opportunitieso Create a Research Advisory Committee which includes senior research faculty members

Provide specific recommendations to departments and centers for potential research development and faculty development

Assist in development of semester Biomedical Sciences Course (see above) Provide recommendations to Associate Dean for Research on web development Assist in selection of Dean’s Distinguished Lectureship nominees

o Develop mechanism through SOM or LSUHSC to better address research infrastructure needs, particularly core laboratories

Consider feasibility of creating SOM Research Infrastructure Committee under Associate Dean for Research

Undertake needs assessment for new cores Make recommendations for best utilization of resources

Standardize core facilities operations and chargeso Improve SOM Office of Research web-based tools

Improve research website


Develop relevant links to active research units Hyperlink to large funded programs Develop thematically based link to individual investigator research

strengths and interests Post recent news and funding opportunities

Data Base for Researchers Catalog expertise, major research equipment, and scientific

accomplishments Identify available research opportunities or collaborations for students,

house officers, and junior faculty o Enhance SOM “Scientific Programs”

Consider Grand Rounds Panel Series with clinical and basic science faculty involvement

Encourage research seminars within all departments/centers Assess feasibility of SOM seminar series featuring junior faculty Consider seminar series in technology transfer Encourage regular interactions between Office of Technology Transfer and

research faculty members Create Dean’s Distinguished Lectureship Series for a noteworthy visiting

professor

b. Summarize institutional efforts or programs that address research ethics, scientific misconduct, conflicts of interest, and human subjects protection. List the administrative units that oversee such programs, and describe their target audiences.

The LSUHSC-NO “Human Subjects Protection Program” is managed by Kenneth Kratz, PhD, Director, LSUHSCOffice of Research Services (ORS: http://www.lsuhsc.edu/no/administration/rs/). In addition to Dr. Kratz, this program has three full time coordinators. Dr. Kratz acts as chair of the Institutional Review Board (IRB) portion of this program that provides review, approval, and oversight of all human subjects research at LSUHSC-NO. The program currently manages over 600 studies, half of which are greater than minimal risk clinical trials. Policies and procedures of the IRB and all forms related to human subject protection are available at the IRB website at the following URL: http://www.lsuhsc.edu/no/administration/rs/irb/default.htm .The program uses the Collaborative Institutional Training Initiative (CITI) for its mandatory training in human subject protection. All members of all human subject research teams must complete this training. This includes faculty, staff and students who are involved in these projects. The learning modules within CITI required by LSUHSC-NO include not only training in human subject protection but also Good Clinical Practice and research misconduct. Access to the CITI website and LSUHSC-NO instructions for use of the program are available through the IRB website listed previously.

Research misconduct is monitored by the Vice-Chancellor for Academic Affairs, Joseph M. Moerschbaecher, PhD. He acts as the Research Integrity Officer who conducts investigations of research misconduct under the LSUHSC-NO research misconduct policy and through its assurance with the Office Research Integrity (ORI). This policy (sect. 10.7) is available in the Faculty Handbook at the following URL:http://www.lsuhsc.edu/no/administration/academic/FacultyHandbook.pdf . As required under the assurance, a report on cases of research misconduct (plagiarism, fabrication of data, and falsification of data by faculty, staff and students) is provided yearly to ORI. As listed at the following URL: http://www.lsuhsc.edu/no/administration/academic/StandingCommittees2008-09%20.pdf , a standing


http://www.lsuhsc.edu/no/administration/academic/StandingCommittees2008-09%20.pdf

http://www.lsuhsc.edu/no/administration/academic/StandingCommittees2008-09%20.pdf

http://www.lsuhsc.edu/no/administration/academic/FacultyHandbook.pdf

http://www.lsuhsc.edu/no/administration/rs/irb/default.htm

http://www.lsuhsc.edu/no/administration/rs/

Committee on Scientific Misconduct is appointed by the ORI. This committee helps in the investigation of cases of research misconduct and makes recommendations to the Institution through the ORI as to the outcome of its investigations.

Policies and procedures with regard to conflicts of interest in research projects are outlined in Chancellor’s Memorandum 35 (CM 35) available at the following URL: http://www.lsuhsc.edu/no/administration/cm/cm-35.aspx . This process requires investigators to provide an attestation form from all members of a study team (faculty, staff and students) as to whether they have any potential conflicts of interest with the potential sponsor. If potential conflicts exist, then the specific study team member having that conflict must follow the CM 35 process by providing a full financial disclosure. With this disclosure a standing Conflict of Interest Review Committee (see http://www.lsuhsc.edu/no/administration/academic/StandingCommittees2008-09%20.pdf ) develops a management plan for the conflict of interest. If human subjects are involved in the project, then the IRB must review the plan to determine if subject welfare is adequately protected by the plan. Investigators and study team members must agree to comply with the management plan.

All of these programs are established by the LSU Health Sciences Center to fulfill federal regulatory requirements. Just as importantly, however, they help create an environment in which all members of the university sense the weight and need for responsible conduct in research and the ethics which underlie this conduct. The institution attempts to convey such ethics to our medical students through specific courses within the medical school curriculum.

During the second year, case studies that deal with research ethics are presented in the “Legal and Ethical Issues in Clinical Medicine” section of course “Science and Practice of Medicine” (SPM 200). The cases are discussed in groups of 40 students in the Fall and Spring semesters. These cases deal with the following research ethics issues:

The Fall case relates to informed consent in clinical research, and purpose and function of the IRB, including approval, annual review, random monitoring, how human subject research is highly regulated by the federal government, minimizing risks and maximizing benefits, and the equitable selection of subjects. The core dilemma presented in this discussion is how to advance scientific knowledge while protecting human subjects through current regulations and ethical principles based on the Nuremberg Code, the Declaration of Helsinki, and the Belmont Report.

The Spring case relates to scientific misconduct, financial conflicts of interest, Bayh-Dole, etc. legalizing use of research for development and partnering with industry, the violation of the trust - cures such as thresholds and ceilings, bans and separating decisions from funds, disclosures, increased federal government oversight - proposals for disclosure & uniform accreditation, audits and inspections -with some anecdotes of Academic Centers who violated the trust. Finally the larger issue of physician contracts with industry - phase IV post drug approval, etc. - are discussed.

In development, for presentation during the third year, is an amplification of research ethics using the CITI program (CITI learner group: L3 course director Joanne Marier, JD) discussed earlier. This will be a required activity in the “Applied Ethical and Legal Issues in Clinical Medicine” during the student clerkships, beginning in the 2009-2010 academic year. This online training will again examine issues on human subjects protection and scientific misconduct.

And last, in the fourth year, a special topics course “Legal Issues for Providers” is presented during a two-hour lecture to the entire class. Issues related to conflicts of interest and clinician contracts with


http://www.lsuhsc.edu/no/administration/academic/StandingCommittees2008-09%20.pdf%20

http://www.lsuhsc.edu/no/administration/cm/cm-35.aspx

industry are presented. This discussion centers on clinical research with devices and drugs and hired marketing bureau activities.

While course work helps convey the weight and need for research ethics and related programs, it is the actual behavior of the faculty that set the example of appropriate conduct of research. Other areas of ethics education occur in classroom discussion, via activities performed during clerkships, and while students gain practical experience doing research projects, thus insuring that students are immersed in an environment of ethical behavior related to research.

Other programs contribute to this environment including HIPAA research compliance activities monitored by the ORS (http://www.lsuhsc.edu/no/administration/rs/HIPAA/default.htm), Institutional Bio-safety Committee and Radiation Safety Committee activities assisted by the ORS and Office of Environmental Health and Safety (http://www.is.lsuhsc.edu/safety/default.aspx), and the Animal Welfare Program and Institutional Animal Care and Use Committee (http://www.lsuhsc.edu/no/administration/rs/IACUC_Forms.htm), which is managed by the ORS. Ethical and regulatory issues related to these programs are provided to students through their involvement in research programs.

See also information for standards FA-5 and FA-8 in Section IV of the database, and Part A, item (e .) in Section V of the database.


http://www.is.lsuhsc.edu/safety/default.aspx

http://www.lsuhsc.edu/no/administration/rs/HIPAA/default.htm

IS-14. Medical schools should make available sufficient opportunities for medical students to participate in research and other scholarly activities of the faculty, and encourage and support student participation.

It is expected that medical schools will provide an appropriate number and variety of research opportunities to accommodate those students desiring to participate. To encourage participation, medical schools could do such things as provide information about available opportunities, offer elective credit for research, hold research days, or include research as a required part of the curriculum. Support for student participation could include offering or providing information about financial support for student research (such as stipends).

___________________________________________________________________________________

a. Briefly describe the opportunities available for medical student participation in research, including the time periods when students may do so, the number of students involved in each type of program (e.g., MD/PhD, MD/MS, summer research, year out research), and the funding sources that are available to support student participation.

There are currently four programs in the LSU Health Sciences Center that offer opportunities for medical students to participate in research: the MD/PhD program, summer research, the Honors program, and the MD/MPH program. In addition, there are annual Research Day activities in the Schools of Graduate Studies and Allied Health Professions, the Neuroscience Center and the Departments of Medicine and Pediatrics, as well as in several other departments or units within the school, through which medical students can participate in presenting their own research and in learning more about the research being performed at LSUHSC. Additional Seminar Series are sponsored by the Clinical and Basic Science Departments as well as the Centers of Excellence and seminars are widely advertised to the LSUHSC community on the Electronic Bulletin Boards.

Programs through which research is made available to medical students:

MD/PhD Program The traditional time course for the program is the first two years of medical school followed by

3-5 years in graduate school to complete the PhD. Students then return to the 3 rd and 4th years of medical school to complete the MD degree. There are currently 26 students in the MD/PhD program – 6 in the 1st year of medical school, 5 in the 2nd year and 15 in graduate school. Of the 15 in graduate school, 5 will be completing the PhD in 2009 and returning for the 3rd year of medical school. Students are provided a tuition waiver for the first 2 years of medical school. During the graduate school portion of the program, students receive both a tuition waiver and a stipend through the department in which they complete their dissertation research. Currently some students are supported by an NIAAA training grant which has recently been renewed (3rd funding period) by Gregory Bagby, PhD of the Department of Physiology. Some students are funded through National Service Research Awards through NIH. Some students are funded through supplements to NIH grants and individual NIH grants, and, finally, some students are supported by funds from the School of Graduate Studies. The websitesfor the MD/PhD Program are: http://graduatestudies.lsuhsc.edu/MD_PhD.htm and http://www.medschool.lsuhsc.edu/admissions/programs.aspx#MD.

Summer ResearchLSUHSC offers several summer research programs that provide research opportunities for

medical students. All of them focus on research during the 8 week summer break between the first and second years of medical school. One program is the Medical Student Summer Research Fellowship


http://www.medschool.lsuhsc.edu/admissions/programs.aspx#MD

http://graduatestudies.lsuhsc.edu/MD_PhD.htm

which sponsors approximately 15-20 students per year. All students give oral presentations at a the Medical Student Summer Research Forum and then the three top presenters are given travel support to attend the National Student Research Forum sponsored by the University of Texas Medical Branch in Galveston, TX.

There are two other summer research programs. One program under the supervision of Paula Gregory, PhD is a combined program between Tulane University and LSU Health Sciences Center funded by the Louisiana Gene Therapy Consortium, Louisiana Vaccine Consortium, and the Louisiana Cancer Research Consortium. It offers support for medical students at both institutions as well as undergraduate and high school students. Medical students generally participate in this program during the summer between the first and second years of medical school. Approximately 10 medical students are supported through this mechanism per year. The website for this program is: http://www.medschool.lsuhsc.edu/genetics/summer_student_program.aspx.

The other summer research program is under the supervision of Alfredo Lopez, MD, PhD and John Estrada, MD. It had been funded by the National Cancer Institute (“Short Research Experiences in Cancer”) for 20 years, but funding has expired; renewal of funding is ongoing. Approximately 6-8 medical students participate in this program per year which generally supports students between the first and second years of medical school. In addition, matriculating medical students and undergraduate college students participate, such that there are 20 total students who participate each year in this program. Two of these slots are supported by funding from the Stanley S. Scott Cancer Center, indicating institutional commitment to student research in cancer. The goal of this program is to foster an interest in cancer research in students, with the hope that they will pursue this as an ultimate career goal. Significantly, there is an active effort to recruit and place underrepresented minority students into this program, and a number of students each year are from Xavier University, a traditionally African-American institution in New Orleans.

Honors ProgramStudents who have performed well academically during firstyear of medical school and are

interested in continuing their summer research, are invited to join the Honors Program. Their research is performed during available time in the second and third years of medical school, during which they give presentations on their research at least once per year. In their fourth year the students are required to write a thesis and present their research in a seminar setting. The research is supported by the mentor, but the students do not traditionally receive a stipend during the second and third years of medical school. The website describing this program is: http://www.medschool.lsuhsc.edu/admissions/programs.aspx#honors.

MD/MPH ProgramStudents enrolled in medical school are allowed to take courses and complete the requirements

for the MPH degree. Students are not required to pay additional tuition. The accrediting program requires that students receive the same training, i.e. number of hours of coursework, whether they are enrolled in the MPH program by itself or simultaneously with their medical school education. Generally, 3-5 students complete the MD and MPH programs simultaneously. The website with information about the MPH program is: http://publichealth.lsuhsc.edu/Degrees.html.

b. Describe how students are informed about opportunities to participate in research.

Students are informed about research opportunities through the School of Medicine Office of Admissions and Office of Student Affairs, the School of Medicine website, brochures given to medical


http://publichealth.lsuhsc.edu/Degrees.html

http://www.medschool.lsuhsc.edu/admissions/programs.aspx#honors

http://www.medschool.lsuhsc.edu/genetics/summer_student_program.aspx

students at orientation and by personal communication of instructors teaching in their courses primarily during the first year of medical school.

See also Part A, item (d.) in this section of the database.


IS-14-A. Medical schools should make available sufficient opportunities for medical students to participate in service-learning activities, and should encourage support and student participation.

“Service-learning” is defined as a structured learning experience that combines community service with preparation and reflection. Students engaged in service-learning provide community service in response to community-identified concerns and learn about the context in which the service is provided, the connection between their service and their academic coursework, and their roles as citizens and professionals [Definition from Seifer SD. “Service learning: Community-campus partnerships for health professions Education.” Academic Medicine 1998;73(3):273-277].

“Sufficient opportunities” means that students who wish to participate in a service-learning activity should have the opportunity to do so. To encourage student participation, medical schools could do such things as developing opportunities in conjunction with relevant communities or partnerships, providing information about available opportunities, offering elective credit for participation, or holding public presentations or public forums. Support for student participation could include offering or providing information about financial and social support for student service-learning (such as stipends, faculty preceptors, community partnerships).

___________________________________________________________________________________

a. Is some type of service learning experience required, either as part of a regular course or as a selective? If yes, describe.

The Service Learning Elective (SLE) offered at the LSU School of Medicine provides multiple opportunities for students to participate in community service activities. Students with over 75 hours service learning by the beginning of their fourth year of medical school will have their SLE hours mentioned in their MSPE (i.e., Dean’s Letter) when applying to residency programs. The SLE is composed of Professional Development and Community Service hours. If a student chooses not to complete 75 hours towards SLE credit, no mention of the elective is made. Consequently, students are encouraged to complete the elective, but are not penalized if they do not.

b. Briefly describe the opportunities for medical student participation in voluntary service-learning activities. Include the types of service learning opportunities that are available, the general level of student involvement, and the sources and level of funding available for such activities.

Students can receive SLE credit hours through projects run by various student organizations (see Appendix). Projects are pre-approved for credit hours by submitting a proposal to the Student Government Association (SGA). Some organizations require participation in at least one of their community service projects to be considered an active member.

Funding for student organizations and their community service projects is available through student government or through individual fund raisers conducted by each organization. For example, every year, the medical school sponsors a 5K race at Audubon Park in New Orleans called Tiger Run. Registration is open to the public and the entry fee is between $15 and $20. Money raised by Tiger Run is divided between the student-run homeless clinic and the SGA activity fund. Throughout the year, student organizations can submit a proposal to SGA and request funding for approved projects from the activity fund. Many student-run interest groups hold fund raisers at the beginning of the year and collect dues from their members. Additionally, grant requests to national agencies may be made for


financial support. In addition to student leadership of these organizations, at least one faculty advisor provides oversight. Of note, 45.7% of Class of 2009 received SLE credit.

Below are some historical examples of student organizations and their respective community service projects:

Admissions tours – college day tour guide (3 hours/tour) American Medical Association

o Stroke/diabetes screenings (2-4 hours/session)o Glaucoma screening (3 hours/training session)

American Medical Student Associationo Blood pressure & glaucoma screenings (1-5 hours/session)

Asian Pacific-American Medical Student Associationo Blood pressure & glaucoma screenings (2-6 hours/session)

Camp Tiger: a weeklong camp put on by first year medical students for disabled childreno Counselor (40 hours/week)

Christian Medical and Dental Societyo Medical mission trip (60 hours/week)

Day with the Docs: high school students interested in medicine get an interactive tour from a medical student’s perspective

o Tour guides (3 hours/session)o Teaching sessions (3 hours/session)o Emergency care (3 hours/session)o Student panel (1 hour/session)

Edgar Hull Society (Internal Medicine Interest Group)o Ozanam Inn (homeless shelter) volunteer (3 hours/clinic)

Emergency Medicine Interest Groupo Teaching CPR to high schoolers (3 hours/teaching session)o Choking awareness (1.5 hours/session)o Healthcare provider renewal class (4 hours/class)o Pediatric Basic Life Support (4 hours/class)o Community healthcare provider class (8 hours/class)

Family Medicine Interest Groupo Tar Wars: anti-smoking campaign in local schools (3 hours/class)o Eighth grade career day presenter (3 hours)

Geriatric Medicine Interest Groupo Blood pressure screenings (1-2 hours/session)o Senior Olympics (up to 6 hours)

Hispanic Clinico Clinic volunteer (1-4 hours/session)

Student-run Homeless Clinicso Adult clinic volunteer (4 hours/session)o Ob/Gyn clinic volunteer (3 hours/session)o Pediatric clinic volunteer (3 hours/session)o HIV counselor training (14 hours)

Integrative Medicine Interest Groupo Whole Foods blood pressure screenings (4 hours/session)

Habitat for Humanity (hours vary by project) Obstetrics Interest Group


o Labor and delivery beautification volunteero Prenatal education classes (2 hours)o Ob/Gyn clinic volunteer (up to 5 hours/day)

Pediatric Interest Groupo Young Docs presentation leaders and volunteers (2-4 hours/session) o Children’s Hospital bingo nights and movie nights (3 hours/session)

Psychiatry Student Interest Groupo National Alliance of Mental Illness patient education volunteer (2 hours)

Public Outreach Depression Screening Programo Training (1 hour/session)o Screenings (4 hours/session)

Relay for Life participants (up to 12 hours) Student International Health Organization

o Clinic volunteer for 7 day mission trip (8 hours/day)o Conversational Spanish clinic (3.5 hours/clinic day)

Student National Medical Associationo Health professions high school recruitment (2 hours/visit)o Health professions tour guide (4 hours/tour)o Summer science interviews (up to 10 hours)o Trick-or-Treat at Children’s Hospital (2 hours)o Nursing home visits (up to 3 hours/visit)

Students Making It a Little Easier (SMILE)o Children’s Hospital clinic parties (3 hours/party)o Christmas toy distribution at Children’s Hospital (up to 4 hours)o Audubon Zoo trip (4 hours)

Women in Medicineo Race for the Cure volunteer (hours variable)

c. Describe how students are informed about opportunities to participate in service-learning activities..

There are many ways that medical students are informed about service-learning activities, beginning with their acceptance to the Louisiana State University School of Medicine in New Orleans. Each student is provided material prior to medical school that contains relevant information about service-learning opportunities such as Camp Tiger, the freshman class service project. These packets also contain information about the many student-run organizations on campus. These organizations and their meetings are major mechanisms by which information regarding service learning opportunities is communicated. At the beginning of the school year, an organization fair is held to introduce the new students to the opportunities that are available to them through each organization. At this time, students are encouraged to attend each organization’s initial meeting.

Through the school’s service learning elective (SLE), students can learn about the service-learning projects associated with each organization, and also the amount of elective credit that is awarded for each project. As each organization prepares for an upcoming project, students are sent emails informing them of how they can get involved. Usually, each organization has several meetings each semester, providing additional opportunities for informing interested students about service learning opportunities. Needless to say, student organizations encourage all of their members to become involved in these projects. In addition to the individual organization-specific emails, the SGA’s elected secretary sends out weekly announcements to the entire student body, informing them of upcoming


events as well as who to contact if interested in participating in service-learning opportunities. Some recent student volunteer work has received national media attention by helping to rebuild Hurricane Katrina-destroyed houses through the St. Bernard Project. Media coverage is another method for informing students and the local community about the efforts occurring at the medical school.

Specifically, here is a recent e-mail sent to the students regarding SLE:

From: Mai, Sophia V. Sent: Thursday, January 22, 2009 9:18 AMTo: MEDICINE 2012Subject: SLE information

As promised, below is a summary of top points discussed in McKenzie Mayo’s SLE presentation on Wednesday. Because the Service Learning Elective (SLE) is an ongoing project, I recommend that you bookmark these points for future reference (I also attached it in a word document).

SLE is not required, only encouraged. Upon completion, it will be included on your transcript.

There are 2 separate components to SLE: Professional Development (PDE) and Community Service (CSE). You can earn only CSE credit or only PDE credit, both, or none.

To earn CSE credit you must complete 75 hours in at least 3 different activities. These are activities that benefit the community outside of LSU. Examples include the usual volunteering activities like blood drives, homeless clinics, or mission trips.

To earn PDE credit you must complete 75 hours in at least 3 different activities. These are activities that are needed to implement a community service activity or develop peer education programs. Examples include mock practicals, interview tours, planning for Camp Tiger.

Projects from CSE and PDE can overlap. You do not have to have a total of 6 different activities to earn both CSE and PDE. You just need 3 different activities for each SLE component.

Activities must be completed from the start of 1st year to October of your 4th year. The only exception to this is Camp Tiger (the summer before your first year).

Only activities listed on the approved list provided by the SLE committee may be included on the SLE form (the list is attached). If it is not listed on the list you must submit a proposal to the SLE committee to be voted on during the next committee meeting. You may get proposal information and examples from the class secretary.

The form is to be filled out every semester for the previous semester (for example, you will complete the Fall 2008 SLE form in Spring of 2008) and submitted to the class secretary before the deadline.

Each activity listed on the form must be confirmed by signature or email.

At the end of each semester, the class secretary will compile a spreadsheet with the each person’s hours. She will be able to tell you how many hours you have accumulated as well as if you qualify to earn the credits.


The deadline for submitting Fall 2008 SLE forms is March 20, 2009 (This is 2 weeks after the 2nd test so there is adequate time for everyone!). Directions for completing and submitting forms are below:

Print out an attached SLE form and fill out activity information including the date, name/organization, and number of hours. There is a column for approval by the coordinator that must be signed. If you cannot get a physical signature, an email confirmation is acceptable. Please print the email and staple to the form.

There will be a box underneath the NTS folders in the atrium of the MEB. Please deposit all forms in the box by March 20, 2009. At the end of each week, I will try to send an email to individuals confirming recipient of the form.

Christian Hernandez (VP of community affairs) and I will be meeting with the SLE committee sometime this month or in February. There is still some confusion on whether committee members for Camp Tiger (aside from the committee chairs) are eligible to earn PDE credit. As soon as a clear and concise decision is made on the issue, I will inform the class. As for now, please fill out your SLE forms (it doesn’t take long at all) and if you have any questions about any aspect of SLE, please do not hesitate to email me. Also, I added a calendar on our bulletin board outside of the lecture hall with our weekly schedules (including lectures, DXR, SPM schedules, holidays, and social events). I’ll update this every month. If you have any other suggestions that would make our academic lives easier and flow more smoothly, please email me.

Thanks,Sophia MaiLSU-SOM, Class of 2012Phone: (504) 975-9177e-mail: [email protected]


IS-15. All medical school faculty members should work closely together in teaching, research, and health care delivery.

Because the education of both medical students and graduate physicians requires an academic environment that provides close interaction among faculty members, those skilled in teaching and research in the basic sciences must maintain awareness of the relevance of their disciplines to clinical problems. Conversely, clinicians must maintain awareness of the contributions that basic sciences bring to the understanding of clinical problems. These reciprocal obligations emphasize the importance of collegiality among medical school faculty across disciplinary boundaries and throughout the continuum of medical education.

___________________________________________________________________________________

Describe any organized activities or events that promote faculty collaboration in the achievement of the school’s missions and goals, such as integrated teaching efforts, collaborative research projects or programs, or faculty development activities. Note any obstacles (such as geographic separation) that may impede collaboration and describe how they are mitigated.

The committee canvassed Department Heads in the Clinical and Basic Sciences Departments. The following tables give examples of collaboration in the three areas outlined above.

Basic Science Departments

DEPARTMENT TEACHING RESEARCH SERVICEAnatomy The Department offers

first year Medical Students courses such as, Human Prenatal Development, Medical Gross Anatomy and Medical Neuroscience in conjunction with Pediatrics, Surgery, Genetics, and Neurology. Fourth year Medical Students collaborate with Surgery, Radiology, Pathology, ENT and OB/GYN in the Senior Surgical Anatomy Elective.

Biochemistry The Biochemistry faculty collaborates with other Basic Science Departments in team teaching the first year

A Bioinformatics Specialist collaborates with investigators from Biochemistry and other Departments in the

The Department is joined with Physiology, Pathology, Genetics, OB/GYN, Anatomy, Psychiatry, Neuroscience


jletou, 04/03/09,

Mention Whitworth and CAP courses with Departments of A, B, C.

jletou, 04/03/09,

Add collaborative research with NSC involving Drs. X, Y, Z

graduate course, Integrated Graduate Curriculum (Cell Biology & Development) for the Graduate School of Biomedical Sciences.

Teaming with Pharmacology, first year Medical Students are offered Medical Pharmacology and Medical Biochemistry.

School of Medicine on bioinformatic projects involving protein and gene sequence analysis, in addition to software development.

Other collaborations with Pharmacology have resulted in two submitted grants with the topic of determining the structure of specific proteins. Collaborations with The Cancer Center and Ochsner Foundation Clinic are on the role of ISG15 in cancer progression and Parkinson’s disease.

Collaborations with Pathology, Biostatistics, Pharmacology and Genetics are on the etiology of breast cancer.

Center, LSU Alumni and the LSU Foundation to participate in Strategic Planning and Communications workgroups.

Genetics The Department offers a multitude of courses in association with other Departments. First year Medical Students are offered Medical Genetics through the Medical School and Pediatrics. Genetics Through Lifespan is offered at the Nursing School. Genetics in Physical Therapy is offered to Physical Therapy Students through Allied Health. First year graduate students take Molecular Biology and Control of Gene Expression, working with the Biochemistry Department. Other classes are offered

The Department collaborates on many grants with other organizations such as, Tulane Medical School, Washington University, Mayo Clinic, University of Cincinnati, University of Colorado, Karmanos Cancer Institute, University of Toledo College of Medicine, Saccomanno Research Institute, National Human Genome Research Institute, MD Anderson Cancer Center, National Cancer Institute, National Human Genome Research Institute, Ponce School of Medicine and Nicholls State University.

The Department is joined with Physiology, Pathology, OB/GYN, Anatomy, Psychiatry, Neuroscience Center, LSU Alumni and the LSU Foundation to participate in Strategic Planning and Communications workgroups.

Members of the faculty are associated with the LSUHSC Committee on Women’s Affairs, Faculty Assembly, the Graduate Advisory Council, the Curriculum Committee, the Council on Professional Conduct, the Institutional Biosafety Committee, and the Area


through Allied Health Professions, the Doctor of Audiology program, and Tulane Medical School.

Health Education Center.

Microbiology The Graduate Students, Medical Students and Dental Hygiene Students are offered courses in collaboration with Children’s Hospital, Pennington Center, Hansen’s Center, the School of Dentistry, the Department of Medicine, and Pediatrics.

Research collaborations occur with many Departments, such as Infectious Diseases, Gene Therapy, Pharmacology, Pathology, OB/GYN, Molecular Sciences, Pediatrics, Ophthalmology, and Physiology.

The Department collaborates with Strategic Planning Research and Core Facilities, Radiation Safety Committee, Institutional Biosafety Committee, Teaching Academy Committee, Faculty Senate, N.O. and School Outreach Program.

Pharmacology Students in the Department take Medical Physiology and Pharmacology courses, offered in conjunction with Medicine, MIP, Opthalmology, Genetics, Neurology, Anesthesiology, Geriatric Medicine, Family Medicine and the School of Allied Health.

The Department participates in a Seminar series and Journal Club with Physiology.

We have an R01, NIDA funded grant with Physiology, Microbiology, Animal Care and Pathology regarding THC impact on SIV progression.

Our COBRE grant is with Physiology, Biochemistry, Pathology and Surgery, “Mentoring in Cardiovascular Biology”.

Physiology The department teaches 1st year medical students, nurse anesthetists, and graduate students.

Collaborative teaching arrangements exist with Jimmy Cairo, PhD and Ben DeBoisblanc, MD at the School of Allied Health Department of Medicine.

The THC impact on SIV progression R01, NIDA funded, project involves the following Departments or Schools: Physiology (Molina, PI), Pharmacology (Winsauer, Varner), Microbiology (Amedee), Animal Care (Birke) and Pathology (Zeiske, Troxclair).

The Department is joined with Pathology, Genetics, OB/GYN, Anatomy, Psychiatry, Neuroscience Center, LSU Alumni and the LSU Foundation to participate in Strategic Planning and Communications workgroups.

Clinical Science Departments


DEPARTMENT TEACHING RESEARCH HEALTH CARE DELIVERYAnesthesiology The Department

provides lectures to the medical students within the Pharmacology, Surgery & Neuroscience Departments. Lectures and simulation teaching on airway management are offered to the Emergency Medicine residents. Teaching is provided by attending staff to ER, Surgery, and Anesthesia residents, as well as medical students and critical care fellows in the Trauma ICU. The Department collaborates in the multidisciplinary Pain Fellowship that includes Neurology, PM&R, Psychiatry and Anesthesiology fellows. A clinical Gross Anatomy course is offered to medical students, interns and residents.

Anesthesiology faculty collaborate on a daily basis with Surgery and Surgery subspecialties in the care of patients in the operating room at University Hospital and Kenner Oschner.

Dermatology

Collaborations with Eugene Woltering in Surgery – angiogenesis studies in psoriasis patients using anti-angiogenesis agents.

A collaboration with Dr. Ouhtit in Pathology-Genetics on melanoma and non-melanoma skin cancer patients.

Family Medicine An interdepartmental project between Family Medicine and Pediatric Genetics: to establish etiological diagnoses for adult patients with developmental disorders.

In collaboration with

The revamping of the community ICU at YYY Medical Center was done to facilitate dialogue between academic intensivists and community physicians who are accustomed to an open-model ICU.


jletou, 04/03/09,

SELAHEC????? Rural Scholars Track?

Family Medicine, patient recruitment for studies are conducted by the Department of Nephrology.

Internal Medicine:

Gastroenterology

Geriatrics

Hematology and Oncology

The LSU Tumor Board has collaborations with the LSU Department of Surgery and the Department of Medicine.

The Carcinoid Clinic, a subspecialty clinic based at Ochsner-Kenner Medical Center, is composed of LSU surgical and medical specialists.

Assistant Professor, Shier Sission collaborates with medical students, internal and family medicine residents.

In the School of Allied Health, LSU PT and OT students rotate at the John Hainkel Nursing Home, for which we have responsibility for the delivery of medical services.

Public Health – currently working with an MPH candidate from the School of Public Health regarding research in the area of vaccine use in nursing home populations.

LSU Dental School has developed a contract affiliated with the LSU John Hainkel Nursing Home, for which the section provides delivery of care, providing ongoing dental/oral and hygiene care.

The Cancer Center supports a seminar series that provides a forum for faculty across the School of Medicine to hear speakers on a variety of research topics.

The Department works with Cancer Center researchers in developing collaborative projects.

The Cancer Centerprovides support for surgical specialists for clinical trials (NSABP, etc.)

The Tumor Board organizes the ongoing multi-disciplinary conference, enhancing resident, fellow, and student teaching, as


Infectious Diseases

well as multi-modal patient care for cancer patients.

Surgery, Urology, Gynecology, Orthopedics and Medical Oncology and Hematology are jointly developing a central access number for patients with cancer.

Several faculty participate in the second year MIP course as lecturers and Julio Figueroa is the Co-Director of this course.

The Infectious Diseases (ID) research programs intersect with many Departments at the Medical Center, especially Microbiology.

The ID STD core lab supports Microbiology faculty research programs, providing clinical specimens for projects. Members of the ID section and MIP faculty are co-investigators on several grants.

Other Departments having collaborations in research are: Pediatrics, through the Research Institute for Children at Children’s Hospital; Physiology; Pathology; OB GYN; School of Public Health; the Gene Therapy Program; the Stanley Scott Cancer Center; and, the Dental School. Active research collaborations exist in the Section of Pulmonary Medicine.

Major collaborative clinical endeavors are located in the HIV Outpatient Clinic on South Roman Street, collaborating with the following Departments: Ophthalmology, OB GYN, Dermatology, Oral Surgery and General Dentistry (Dental School) and Psychiatry.

The Department has a The Department has The Department


Nephrology and Hypertension

Physical Medicine and Rehabilitation

bi-monthly joint case presentation with the Section of Rheumatology. Lectures are held in conjunction with Family Medicine, Physiology, Radiology, Physiology and Pharmacology.

The Department also participates in lecture series with Tulane School of Medicine, Physiology, Tulane School of Public Health, Geriatric Board Review Course, and Family Medicine Review Course.

Pharmaceutical Industry Grants: five clinical research trials (ongoing), Geriatrics has three ongoing and one that terminated in 2008, and Family Medicine has one ongoing and three performed/completed between 2006-2008.

The Department, along with the Department of Comparative Medical Sciences,LSU School of Veterinary Medicine, and the Department of Pathology, Tulane Medical School has a Pharmaceutical Industry Grant, PI initiated, bench research in 2005 – 2009.

participates in activities and public service with the Louisiana Public Hospitals, leader of disease management (hypertension).

Residents and fellows of Trauma, Orthopaedics and Neurosurgery are taught about exams, prognosis and early management of SCI and TBI, along with management of agitation in TBI and clinical issues, i.e., vent weaning in high SCI.

PM &R hold lectures several times each year for the School of Allied Health (PT/OT) and participates in the interdisciplinary Musicians’ clinic.

Having one of the few PM & R ACGME

PM &R participates heavily in the Trauma program, including preparation for the site visit that led to certification as a Level I Trauma center.

The Department helped develop the policy that all SCI, TBI and major amputation cases are evaluated by a protocol that involves consult of PM & R within 2-3 days post trauma.


Pulmonary/Critical Care Medicine

accredited Pain fellowships in the country, this program merged with Neurology to allow a broadened training opportunity for the fellows.

PM & R participates in weekly interdisciplinary pain programs with LSU, VA and Tulane trainees and faculty.

The Department has a joint appointment with the School of Public Health in the Environmental and Occupational Health Sciences, a grant with the Alcohol Research Center and an Alcohol Training Grant with the Department of Physiology.

Freshmen are offered a Physiology Course through joint appointments with the LSU Department of Physiology. Other lectures include the Departments of Pharmacology, Surgery and the Dental School.

Research collaborations include the Department of Genetics, the Gene Therapy Program, the Cancer Center and Tulane Gene Therapy Program.

The Department has an Alcohol Research Center T32 Training Grant from the Alcohol Research Center, as well as a grant from the Gene Therapy Center on Tuberculosis, and one from the Environmental Protection Agency on Oxidase and Iron Metabolism.

Research with Tulane University involves immunosuppressive neuropeptides in animal models of collagen-induced arthritis and psoriasis and psoriatic arthritis. This is in collaboration with the Tulane

Monthly Renal-Rheumatology Conference, Monthly Citywide Rheumatology Conference (in collaboration with Ochsner Medical Center Rheumatology Department).


Rheumatology

University Peptide Center, funded by the LA State Board of Regents.

Role of Chlamydia trachomatis in Reactive arthritis: In collaboration with the University of South Florida College of Medicine. Funded by the National Institutes of Health.Psoriatic arthritis outcome measures:In collaboration with GRAPPA (an international research group for the study of psoriatic arthritis).

Neurology Neurosurgery – medical students (MS IV) do a combined 4-week rotation for Neurology/Neurosurgery with shared faculty teaching responsibilities and lectures.

Residents from Neurosurgery do Neurology electives in University Hospital (UH) and faculty clinics; residents from Neurology do electives on Neurosurgery at UH and West Jefferson Hospital; monthly combined Neurology and Neurosurgery grand rounds.

Pediatrics – residents rotate through pediatric neurology, which is within the Department

Radiology – several collaborative research projects in multiple sclerosis and cognitive/behavioral neurology supported by the NIH.

Neurosurgery – several collaborative projects in deep brain stimulation to assess benefit and cognitive changes- these are both animal and human studies; several collaborative projects in epilepsy via the Epilepsy Monitoring Unit (EMU) at West Jefferson Hospital.

Psychiatry – several collaborative research projects in epilepsy surgery and epilepsy pharmacological therapy.

Psychiatry- PGY1 rotations (required) in Neurology .Pediatrics- upper level pediatric resident rotations (in pediatric neurology).

Neurosurgery – collaborative efforts at UH , CH, and West Jefferson Hospital; the Epilepsy Monitoring Unit (EMU) at West Jefferson Hospital is a joint venture of Neurology and Neurosurgery.

Stroke team at UH is a collaborative effort between neurology, neurosurgery, medicine, critical care, radiology, emergency medicine, and rehabilitation services.


of Neurology.

Pathology – weekly lectures and pathology conferences at Childrens Hospital (CH).

Cell Biology and Anatomy – neurology faculty teach in the Neuroscience course for MSI .

Medicine – PGY1 Neurology residents do one year of internal medicine at LSUHSC.

Psychology – several collaborative research projects in autism spectrum disorder and developmental stuttering at CH in cognitive/behavioral neurology and pediatric neurology and with Psychology at Tulane.

Pharmacology – collaborative projects in neuropathic pain and sodium channel pathophysiology. These studies are also done in collaboration with the Department of Physiology at the Univ of Colorado.

Neuroscience Center – NIH funded projects on brain ischemia and epileptogenesis in conjunction with Dr. Nicolas Bazan.

Sleep lab at UH is a joint effort between neurology and Pulmonary Medicine.

Memory Disorders Clinic at Ochsner Medical Center is a joint effort between Cognitive/Behavioral Neurologists from LSUHSC and neurologists, psychiatrists, and social services from Ochsner.

Neurosurgery Monthly inter-departmental epilepsy conference is held with Neurology Department. The faculty presents 10 lectures in the first year Medical School Neuroscience course, as well as a lecture on anatomical dissection for the fourth year Medical School of Surgical Anatomy. Monthly lectures are presented to the senior Medical School Clinical Neuroscience rotation.

The Department is collaborating with the Neuroscience Center of Excellence on funded projects investigating the treatment of chronic pain, reversal of re-perfusion stroke injury, and mechanisms of growth in malignant primary brain tumors.

The OMFS service has a four month rotation of one of their first year residents on the Neurosurgery service. That resident is fully incorporated into the service and functions as a first year Neurosurgery resident.

Obstetrics & Collaborative efforts ID – HIV research PGY1 rotations for


Gynecology with other departments:Anatomy – annual lectures on pelvic anatomy, cadaver dissections and cadaver surgical procedures. Pathology – weekly pathology conferences.Pediatrics – teach PGY1 newborn resuscitation and life support certification and pediatric & adolescent gynecology lectures.Family Medicine (FM) – lecture residents in FM for their didactic curriculum and FM residents rotate in OB/GYN clinics.Surgery – laparoscopic simulation skills training, joint surgical skills curriculum and SAGES/FLS.

project collaboration between faculty and resident and Chlamydia resident research project.OMERAD – research study design and analyses, education effectiveness, interdepartmental collaboration and facilitate inter-school collaboration.

Emergency Medicine and Family Medicine residents. Family Medicine OB coverage at UMC to support program.

Ophthalmology MS II surgical rotation elective- 2 wk ophthalmic clinic/surgery rotation.

MSIII Clerkship (10 days) Lectures and workshops on Ophthalmology.

Residents- Collaborative teaching of LSUHSC Family Practice residents in Bogalusa, Lafayette, UH, MCLNO, EKL and private clinics.

Internal Medicine- Lecture series 2/yr.

Microbiology, Immunology & Parasitology (MIP) – several collaborative research projects in HSV gene therapy and Epstein bar virus.

Neuroscience- several collaborative projects investigating the relationship between Alzheimer’s and HSV and the effects of oxidative stress on retinal epithelial cell function.

Cancer Center- collaborative projects on immunological suppression.

Numerous consults with all clinical departments on individual patient care at the MCLNO, UH, Lafayette, Bogalusa, EKL, and private clinics.


Dental School- collaborative project on polymer material analysis.

MSIV Research rotation (1 month) with departmental research faculty.

Orthopaedics The Orthopaedic Department has a teaching relationship with the Anatomy Department.

Collaborations occur with Microbiology and ID on biofilm formation on various materials.

Research collaborations with the Department of Pathology to investigate articular cartilage.

An internationally recognized bioengineer who is a clinical faculty member, is supported by the Brown Foundation.

The LSU Hand Surgery Program has collaborations with Plastic Surgery.

Orthopaedics is participating in the spinal deformity study group, with a data base of over 5,000 cases.Orthopaedics collaborates closely with Surgery in the level one Trauma Center at the LSU interim hospital.

Otorhinolaryngology The Department has a teaching relationship with the Department of Anatomy, presenting an Emergency Airway/Cricothyrotomy Workshop to over 100 first-year students and three hours of neck dissection and parotidectomy anatomy and surgical techniques lectures as part of an elective course received by fourth year students. Students and residents participate in conferences, such as the multi-disciplinary Tumor Board, which enhances teaching and patient

Faculty members with an interest in research are encouraged to submit proposals. To further development of faculty research through collaborative efforts, the Chairman will serve as a liaison to research directors and principal investigators throughout the school.

The Department collaborates with the Departments of Pediatrics and Family Medicine at Children’s Hospital of New Orleans in the care of pediatric patients, as well as student and resident education.

The Department participates in the Surgery clerkship of third year students, and provides a fourth year elective to seniors. During the junior rotation, students rotate through Our Lady of the Lake


care for head and neck oncology patients. Mentoring from faculty is provided to those interested in entering an Otolaryngology-Head and Neck Surgery residency program. Faculty sharpens their teaching and mentoring skills by attending a series of seminars (Teaching the Teachers to Teach), and receiving manuals. These measures promote uniformity and continuity of the different services and the assurance that each faculty member understands their role in resident and student education.

Regional Medical Center, Earl K. Long Medical Center, University Medical Center and Children’s Hospital of New Orleans.

Pathology The Department is involved in teaching sophomore medical students two major courses in the second year. Elective teaching experiences are provided in the senior year and for medical technology students in the School of Allied Health.

Faculty teaches graduate students and MD/PhD students, providing education for gastroenterology fellows, ob-gyn residents and pathology residents.

Research collaborations with the Department of Pharmacology, the COBRE Research Group, and the Cancer Center have been established.

The Department provides service to the Interim LSU Public Hospital, the Bogulusa Medical Center and Children’s Hospital. The Department also serves seven HCSD Hospitals supporting all the laboratories in this system.

Pediatrics The Department has a combined Internal Medicine/Pediatric

The Department of Pediatrics collaborates with the Surgery,


training program.

The Family Medicine residents rotate at Children’s Hospital for their pediatric requirements.

Urology, ENT, and Radiology Departments in the care of pediatric patients at Children’s Hospital.

Psychiatry The Department teaches Science and Practice in Medicine 100 with Family Medicine and Pediatrics Faculty.It assists School of Nursing faculty with instructing students during their psychiatry clinical rotation.The Department assists The School of Allied Health’s Occupational Therapy Department by providing lectures about psychiatric conditions.Neurology residents rotate through the emergency psychiatry service.The Department has a PGY2 course, “Neuropsychiatry”, with faculty from the departments of Neuroanatomy, Neurology, and Neurosurgery who lecture to the residents.The faculty provides lectures for meds/peds residents about psychiatric diagnosis and treatment.Pediatric Neurology fellows rotate through the outpatient child psychiatry specialty clinics.Tulane Social Work interns receive training

Collaboration with Neurology and Neurosurgery in investigator initiated trials for treatment of depression in patients with temporal lobe epilepsy and the study of patients with psychogenic non-epileptic seizures.Collaboration with Pediatrics on research concerning post traumatic stress symptoms and symptoms of depression in children and adolescents following Hurricane Katrina.

Collaboration with Anesthesiology on components of ECT delivery.Collaboration with Surgery to determine the degree of psychopathology in a surgical follow up clinic at a level one trauma center. Collaboration with the Office of Mental Health, Tulane School of Social Work and UCLA on impact and efficacy of State Crisis Counseling and specialized services programs.

Consultation with all departments at University Hospital related to combined medical/surgical and psychiatric needs.Planned collaborations to evaluate patients prior to Bariatric surgery.Collaboration with Neurology and Neurosurgery in the Epilepsy Center of Excellence with referrals for pre-operative evaluations for DBS implantation and implantation of spinal cord stimulators. Collaborative consultations with the Department of Pediatrics on outpatient specialty needs at the Department’s outpatient clinics.Provision of psychiatric inpatient care in collaboration with Pediatrics at the Children’s Hospital/Evergreen Health Management Adolescent Unit (just recently accomplished).


jletou, 04/03/09,

Research collaborations at the CRI exist in the general areas of infectious disease, immunology, diabetes, and cognitive disorders. Pediatric faculty therefore collaboration with faculty from Departments A, B, and ....

and outpatient and community based psychiatry programs.

Research and collaboration with Medicine, Emergency Medicine and Nursing related to secondary traumatic stress.

Radiology Radiology teaches an annual 2 week course for LSU School of Medicine.

The Department participates in Grand Rounds and gives lectures for various subspecialties, e.g.: Breast Imaging for Surgery Department, Interventional Radiology for OB/GYN and CT-Angiography in Trauma for the Trauma Interdisciplinary Conference.

The Department Chair has worked extensively on restarting a residency program, which will commence in July 2009.

Radiology has collaborated with Orthopedic Surgery and Neurology on Research projects.

The Department participates actively with several departments in University Hospital-LSU Tumor Board (weekly), which involves Clinical, Radiology -Pathology Correlation. Radiology has a representative at the weekly Pulmonary Case Conference, as well as the Internal Medicine Morning Report meeting.

The Department participates in the Trauma Peer Review weekly conference, and the weekly Breast Case Management Conference, which meets in the Medical School, Department of Pathology. All cases are reviewed for Clinical, Radiology and Pathology correlation.

Surgery The Surgery Department has a third year clerkship in surgery coordinating with Vascular, Cardiothoracic, Urology, Pediatric Surgery, Plastics Surgery, ENT and Orthopaedic services.

Working with the Center for Advanced Practice, the Department of Surgery faculty participates in the education of students and residents, and team training of nurses and anesthesiologists.


Carcinoid

Trauma/Critical Care

Vascular

Collaborations with Eugene Woltering’s research with GI med, Dermatology, Oncology, and multiple patients and grants.

The Carcinoid Group has a large national referral practice at Kenner Regional Hospital, with collaborations with GI Medicine and Medical Oncology.

The Trauma Group conducts prevention research with the SPH and multiple research studies on trauma and critical care.

Collaborations with Tulane Surgery and LSU Anesthesiologists on care of trauma and critically ill patients.

Vascular works with Interventional Radiology on stents.

Dr. Bazan acts as Clerkship Director for the Surgery Clerkship.

Dr. Bazan is doing collaborative research on a COBRE grant with Pharmacology.

UrologyThe Department offers 3rd and 4th year clinical clerkships: 2-4 Junior medical students per rotation and 5-7 Senior “sub-internships”. Senior rotations include General Urology, Urologic Oncology and Urologic Research.

In collaborating with Anatomy, residents assist in teaching Junior medical students genitourinary anatomy (assist in dissection). Collaborations with Surgery include faculty lectures at GS trauma conference and grand rounds. The Department participates in Surgery’s Cohn’s Conference and junior surgical small groups. Urology teams with Gynecology in academic

Urology collaborates with the School of Public Health on several projects, including the Metabolic Syndrome in Prostate Cancer (Grant awarded) and NC/LA Prostate Cancer Project (SPORE with Stanley the Scott Cancer Center).

Collaborations with the Stanley Scott Cancer Center involve joint efforts in developing GU malignancy research programs and LCRC Tumor banking with Cancer Center.

Pulmonary Medicine collaborations have resulted in 2 IRB approved clinical trials initiating through pulmonary clinical trials division.

The Department has a Prostate Cancer Screening Directorship and an ESWL Directorship at LSU Interim Hospital. The Proposed Directorship in Urodynamics at LSU Interim Hospital is in direct collaboration with Gynecology, Neurology and Neurosurgery. In collaboration with Urogynecology at EJGH Touro and LSU Interim Hospital, a joint fellowship program has emerged in female pelvic medicine and reconstructive surgery. Collaboration with Ochsner Clinic involves Pediatric Urology, Female Urology and Voiding Dysfunction. Advanced percutaneous stone


instruction of fellows in urogynecology. Urology is joined with Medicine in giving lectures at IM grand rounds.

The Program Director coordinates Urology residents at LSU and Ochsner.

Coordinated faculty research with Dr. Nick Bazan.

management is a result of collaboration with Interventional Radiology at LSU Interim Hospital and EJGH. The Department collaborates with LSU Neurology in the Multiple Sclerosis Clinic and patient outreach programs.

Obstacles: Lack of horizontal and vertical integration of knowledge and resources into the educational

process. Lack of education director at departmental level to direct and re-design entire curriculum. Lack of coordination (cooperation) between departments. Under-development of web based curriculum. Geographic separation (de-centralization) of faculty and students/residents. Lack of time commitment (financial) of faculty. Lack of development of clinical faculty as educators. Poor faculty knowledge of available resource. Lack of commitment for inpatient rehab at UH and delays in start of PM & R and EMB clinics. Barriers to collaboration for Family Medicine remain to be geographic separation, with few

Faculty located downtown and Residencies spread across Kenner, Lafayette, Lake Charles, and Bogalusa.

Competing clinical/administrative demands for clinical faculty participating in research. Departments with which we collaborate are at scattered sites. There are funding challenges for non-clinical positions in light of fiscal uncertainties. Although the Department of Psychiatry is trying very hard to respond to requests, it is difficult to

respond to urgent needs of LSU facilities in other regions of the state.


IS-16. Each medical school must have policies and practices to achieve appropriate

diversity among its students, faculty, staff, and other members of the academic community and must engage in ongoing, systematic, and focused efforts to attract and retain students, faculty, staff, and others from demographically diverse backgrounds.

Aspiring future physicians will be best prepared for medical practice in a diverse society if they learn in an environment characterized by, and supportive of, diversity and inclusion. Such an environment will facilitate physician training in:

Basic principles of culturally competent health care Recognition of health care disparities and the development of solutions to such burdens Importance of meeting the health care needs of medically underserved populations Development of core professional attributes, such as altruism and social accountability,

needed to provide effective care in a multidimensionally diverse society

Each school should articulate its expectations regarding diversity across its academic community in the context of local and national responsibilities, and regularly assess how well such expectations are being achieved. Schools should consider in their planning elements of diversity including, but not limited to, gender, racial, cultural and economic diversity. Schools should establish focused, significant, and sustained programs to recruit and retain suitably diverse students, faculty members, staff, and others.

_____________________________________________________________________________________

a. Provide a copy of all current mission statement(s) and policies at your institution that are related to assuring a diverse student body, faculty, and staff.

The LSUHSC-NO Diversity Initiative envelopes all of the school and campus policies that can be found at the following locations. Slight variations in emphasis occur, due the the particular needs and nature of the segment of the population to which each is addressed.

Faculty Handbook Section 4.4 http://www.medschool.lsuhsc.edu/admissions/Criteria.aspx http://www.lsuhsc.edu/no/administration/cm/cm-10.aspx http://www.lsuhsc.edu/no/administration/hrm/forms/administrative%20Procedures.doc http://www.lsuhsc.edu/no/administration/cm/cm-56.aspx http://www.medschool.lsuhsc.edu/faculty_affairs/pdf/som_strategic_plan.pdf .

Describe the process by which these statements and policies were developed, approved, and implemented at your institution.

The processes involved in the development of these statements and policies are varied. In the case of the Diversity Initiative, a focused plan was developed at the request of the Chancellor. In other instances deficience and/or omissions are adrdressed by the development of new policies or revisions of old ones. If deficiencies were observed, or if situations and needs dictated, these statements and policies were developed and approved via the mechanisms that are established and appropriate for each type of document (e.g., for the Faculty Handbook, Chancellor Memoranda, etc.).


http://www.medschool.lsuhsc.edu/faculty_affairs/pdf/som_strategic_plan.pdf


http://www.lsuhsc.edu/no/administration/hrm/forms/administrative%20Procedures.doc


http://www.medschool.lsuhsc.edu/admissions/Criteria.aspx

The overarching LSUHSC – NO Diversity Initiative was developed by the former Associate Vice Chancellor for Academic and Multicultural Affairs, Loren Blanchard, PhD. It will become part of the Strategic Plan for the LSUHSC-NO along with relevant benchmarks. This initiative was developed primarily by the Associate Vice Chancellor using input from the deans of the component schools of LSUHSC-NO, the faculty and its leadership bodies, and representatives of the student body. It was approved by the Chancellor and is in the process of being implemented.

The Faculty Handbook is the responsibility of the Vice Chancellor for Academic Affairs. The content of the LSUHSC Faculty Handbook is regularly reviewed and revised by a committee representative of the component schools of the campus to maintain consistency with Federal and State Regulations, LSU System Bylaws and Policies, and other over-riding regulations or policies; specific input from the Faculty Senate is sought on Faculty Handbook changes. The handbook specifically references diversity on campus and our equal opportunity policies for hiring. The Chancellor has the authority to approve the content of the Faculty Handbook.

The School of Medicine Admissions Committee reviews its mission statement and introductory page on the web site annually; changes that are made are the consensus product of the committee members and approved by the Dean. Each year the committee members are reminded of the diversity goals of the admissions process. Additionally, orientation for new committee members stresses the importance of a diverse and representative student body. Implementation of these policies is evidenced by the strong record of diversity in matriculated students in the student body. These data are reviewed annually by the Admissions Office and by the Office of Community and Minority Education and reported to the General Faculty, the Administrative Council, and to the Dean.

The website for Human Resource Management outlines the advertisement, recruitment, selection, and hiring process for faculty and staff. The check list on the website outlines how our process and procedures conform to Federal and State Regulations. All EEOC guidelines are adhered to and implemented. The Assistant Manager of Human Resources has the responsibility of drafting the policies, with final approval lying with the Chancellor. Implementation of these policies is evidenced by the consistency with which Human Resource Management requires the submission of appropriate documentation before an individual can be formally hired as faculty or staff. An annual report for the campus on diversity is prepared for the Vice Chancellor for Academic Affairs; this report reviews our collective campus data and relevant sections are appended for reference.

Chancellor’s Memoranda are typically developed by the relevant Vice Chancellor, with or without input from the campus leadership or faculty as needed, and approved by the Chancellor. As mentioned below the Chancellor’s Memorandum #10 affirms our commitment to adhere to all federal and other relevant regulations in regard to hiring practices for faculty and staff. Implementation is addressed in the previous paragraph. Moreover, there are several steps in the recruitment and hiring process (as laid out in the procedural document attached) (ATTACH PROCEDURAL DOCUMENT TO APPENDIX) that demand a process that encourages a broad slate of candidates. The preamble to Chancellor’s Memorandum #56 outlines the rights of students from all backgrounds and implicitly defines our commitment to diversity; the appeal process for students is defined in this document.

The School of Medicine Strategic Plan, recently completed and under implementation, cites diversity and community outreach as overarching goals. The Strategic Plan was developed through a consensus process focusing on specific charges from the Dean by a large number of participating faculty members, faculty leadership, and strategic partners. The participating faculty members were selected to be widely representative of the school, across departments, appointment track and rank, race, and gender; formal


representation by the School Faculty Assembly and the LSUHSC Faculty Senate was also included. The Strategic Plan was presented to the Administrative Council and was approved by the Dean. We are currently in the early stages of implemented many of the initiatives that were developed and included in the Strategic Plan.

Describe how these statements and policies are made known to current and prospective applicants, students, employees, faculty, and staff

Applicants are made aware of the relevant commitments and policies largely through our web and printed materials prepared for the admissions process. Students have access to diversity policies through the LSUHSC and School of Medicine websites and by email distributions on important changes or additions to our policies; the Associate Dean for Student Affairs is principally responsible for communications with students. Policies are discussed at General Faculty Meetings and Administrative Council Meetings. Department Heads and Center Directors are responsible for communicating policy changes and adoption of new policies to their faculty members. There is an electronic subscription service that faculty and staff can use that announces and directly links to all new LSU System and LSUHSC policies. The Chancellor also holds campus Town Hall Meetings that are venues for the entire campus community to learn about new policies and procedures.

b Describe how your institution defines or characterizes diversity for its students, faculty, and staff. What dimensions of diversity are considered? If different definitions apply to any of these institutional constituencies, provide each relevant definition.

In its broadest sense, diversity is the richness of differences - genetic, environmental, and cultural - that results in variety in human beings. A diversity of members in the LSUHSC community is desirable, as it allows all members of the school to experience these differences, become enriched by this exposure, and to respond in an appropriate and beneficial way to those who are different from oneself. This is particualry important in the education of medical students. Physicans diagnose and treat all patients with equivalent professionalism and care, and it is important for our students to be aware of issues that stem from the diversity of the patient population. For example, an understanding of a higher incidence of a disease in a certain racial population or the dietary restrictions of those from different cultures can affect the ability of a physician to efficaciously manage a patient. As far as is possible, LSUHSC-NO strives to promote diversity at all levels on campus.

Formally, we report diversity in accordance with the federally defined categories of American Native, Asian, African American, and Hispanic, as well as gender. However, other subtle dimensions of diversity are also considered, particularly in the admissions process for the entering class, including disadvantaged backgrounds not necessarily driven by ethnicity or race.

In the context of your definition of diversity, describe how your policies related to diversity are put into practice in each of the following areas:

Student recruitment, selection, and retention Financial aid Educational program Faculty /staff recruitment, employment, and retention Faculty development Liaison activities with community organizations


The mission of the Louisiana State University Health Sciences Center in New Orleans (LSUHSC – NO) is to provide education, research, and public service through direct patient care and community outreach. Clearly, our community is diverse by any standard. LSUHSC – NO provides vital public service through direct patient care, including care of uninsured and indigent patients. LSUHSC – NO works cooperatively with two Area Health Education Centers (AHEC’s), whose programs focus on improving the number and distribution of health care providers in underserved rural and urban areas of Louisiana and on supporting existing rural health care providers through continuing education programs.

The Medical School Admissions Committee strives to, as far as possible, recruit and admit Louisiana residents from every geographic, economic, social and cultural dimension of the State of Louisiana. While it is not possible to exactly recapitulate the demographics of the State, every effort is made to recruit as represeantative a student body as is feasible. As stated in the Office of Admissions website, “The primary goal of the School of Medicine in New Orleans is to produce competent, humanistic physicians. In order to meet this goal, the School of Medicine finds that having a diverse student body is essential. Diversity in all its forms benefits students by creating a dynamic, productive, and positive learning environment that promotes better cross-cultural and cross-racial understanding. Ultimately, the benefit of classroom diversity will help the School of Medicine produce individuals who are able to be effective clinicians within a multi-cultural environment.” The Admissions Committee evaluates all applicants in three major areas: humanitarian qualities, overall excellence, and diversity of experience. As part of this process, any and all of the following holistic criteria are evaluated: academic factors, strength of the letters of recommendation, personal interviews with the members of the Admissions Committee, employment history and whether or not the applicant had to work to go to college, community service, quantitative and qualitative assessment of the extracurricular activities, awarded honors, unique personal attributes, hobbies and interests, socioeconomic background, where in the State of Louisiana the applicant was raised, strong motivation to practice in a medically underserved areas of the state, and whether there were any factors in the applicant’s background that may have hindered them from achieving a higher level of academic achievement. The Admissions Committee believes that the proper consideration of these factors will result in our institution matriculating and graduating a cross-section of our state’s population so that these graduates can deliver quality health care to the citizens of the State of Louisiana.

To promote diversity and encourage minority and disadvantaged accepted students to matriculate into our School of Medicine, we offer via financial aid, the Disadvantaged Scholarship. Each year scholarships are provided to qualified students on a yearly basis, provided the student remains in good academic standing. Students are selected on the basis of financial need and scholarship.

Louisiana is largely a rural state, and rural areas do not have enough physicians, resulting in inadequate access to medical care for its residents. The LSU School of Medicine in New Orleans implemented a Rural Scholars’ Track, with a goal to identify and train physicians who will most likely practice medicine in rural settings in the State of Louisiana. We believe the Rural Scholars’ Track will improve the delivery and quality of the rural health care system through a combination of education, service, collaboration, and research specific to these underserved areas of the state. Forty-four students (MS I = 15; MS II = 10; MS III = 10; MS IV = 9) are currently enrolled in the Rural track in the SOM.

More specifically, LSU School of Medicine has developed programs aimed at broadening diversity among their applicants for medical school admission and has major programs in place intended to enhance diversity in the applicant pool. In 1981, LSU School of Medicine established the Office of Minority Affairs, now identifed as the Office of Community and Minority Health Education (CMHE). The mission of the Office is to increase access and improve the quality of health care for all Louisiana residents,


especially the poor, the minority, and the underserved populations, with a vision to increase the number of competent underrepresented minority physicians practicing quality health care and eliminating health care disparities within the State of Louisiana. The Office of CMHE is an administrative unit within the Office of the Dean, and it maintains close working relationships with the Offices of Admissions and Student Affairs. The Office is directed by Edward Helm, MD, MHA, Associate Dean, an administrator nationally recognized for his innovative programs.

Recruitment of underrepresented minority and disadvantaged student representatives of the population for the state of Louisiana is a major goal for the CMHE Office. CMHE has designed activities and programs that will increase minority and disadvantaged students’ awareness of and exposure to opportunities at LSUHSC. Specific programs intended to enhance diversity in the medical school admissions applicant pool are: Recruitment (LSUHSC funded since 1981) unstructured activities: K-12 Science Clubs, K-12 Health Profession Awareness Days, premedical advisor counseling, recruitment visits and tours, medical school counseling, and mock interviews. Preliminary Education (funded by federal grant from 1985-August 31, 2007 and September 1, 2008 to present) structured activity: 8-week High School Summer Science Program for 60 high school junior and senior students each year. Facilitating Entry (funded by federal grant from 1985-August 31, 2007 and September 1, 2008 to present) structured activities: MCAT preparatory review twice/year for 40 college students per review and an 8-week summer Prematriculation Program for newly accepted disadvantaged medical students.

In order to develop a more competitive applicant pool for minority and disadvantaged students within Louisiana, CMHE developed formal educational partnerships (greater than 10 years) with health professions schools (Medicine, Dentistry, Nursing, Allied Health) within the LSU Health Sciences Center, New Orleans Public Schools, Historically Black Colleges and Universities in New Orleans and Baton Rouge, and community physician organizations. Formal linkages between CMHE and their partners exist so that collaborative relationships can provide necessary structured and unstructured programs to assist minority and disadvantaged students. Aside from year-round recruitment visits to academic institutions, planning and coordination sessions are conducted specific to each activity. It must be noted that the LSU School of Medicine provides a supportive environment for all students but wants particularly to ensure the retention and graduation of their disadvantaged students. The Offices of Student Affairs and CMHE, offer academic monitoring and counseling, a mentoring program, and USMLE, Step I and II prep courses, all of which contribute to the success of our students in medical school. The Office of the Dean of the School of Medicine funds individual tutoring for all medical students, if needed, and this is, thus, available to disadvantaged and underrepresented minority students.

The academic community of the School of Medicine is committed to maintaining an environment of open and honest intellectual inquiry. To promote respect for all, the students, residents, and faculty of the School of Medicine adopted a Code of Professional Conduct that governs questions of all professional conduct. As stated in the Preamble for the Council on Professional Conduct, “… faculty, residents, and students have the right to enjoy an educational environment characterized by the highest standards of ethical professional conduct. The individuals who comprise the LSUHSC campus come from different cultural backgrounds. The students, residents, and faculty share the responsibility, to themselves and to their colleagues, to protect their individual rights and those of the academic community as a whole.”

Through an Honor Code, the students of the LSU School of Medicine affirm their adherence to promote a mutual trust and honor among faculty, students, and staff. The Mission Statement for the student


Honor Code states, “As future physicians, we must maintain our educational pursuit at a level consistent with the integrity of our chosen profession. We believe that ethics, social responsibility, and academic integrity are an essential part of our experience as medical students in a diverse community that encompasses a wealth of people and their experiences. Violation of these basic principles will be considered an Honor Offense.” Specific situations that are considered concerning for any of our student body are referred to the Council on Professional Conduct with the understanding that our students are entitled to study and pursue their professional and personal aspirations in an environment that is free from any type of disrespect.

In 2008, the School of Medicine formally adopted a revised set of curriculum objectives. Our curriculum focuses on the acquisition of basic skills in the core areas of physician competence. Student competencies are taught and evaluated in the classroom, in simulation labs, and in training hospitals and clinics. Some of the student competencies include respect for the patient’s autonomy and cultural beliefs and for communication competencies that include the need to understand and overcome the patient’s literacy, linguistic, or cultural barriers. New curriculum initiatives are developed and monitored by the Curriculum Oversight Committee, which aim to ensure that the overall goals and objectives are achieved. First-year medical students are provided with Clinical Forums in their Science and Practice of Medicine 100 course, where medical ethics, professionalism, patient-physician communication, human development, social issues, cultural competency, and healthcare policy lend themselves to discussion in small group formats. In turn, the Curriculum Evaluation Committee is responsible for evaluation of the content and success of individual courses and clerkships. Our residency programs also endorse and teach “6 Core Competencies”, with an emphasis on sensitivity to a diverse patient population as the fifth competency.

The Dean has also recently appointed Paula Gregory, PhD to serve as Director of Faculty Development. Dr. Gregory will be charged with organizing and distributing information on the many faculty development initiatives already in plance and with supporting faculty orientation, career planning, and special support for minority and women faculty. Dr. Nelson, as dean, has also encouraged and been supportive of faculty participating in AAMC programs targeted at minorities and women and in ELAM, which is targeted at women seeking leadership roles within academic medicine.

Also, Dr. Nelson has recently appointed Dwayne Thomas, MD, MHA as Associate Dean for Health Care Quality and Safety. Currently, on special assignment with David Satcher, MD, as a fellow in his health disparities program at Morehouse School of Medicine, Dr. Thomas will play a critical role in the implementation of modules dealing with health care disparities into the undergraduate and graduate medical education programs and in educational and interventional programs for our faculty.

Finally, the varied community service activities involving our student body, house officers, and faculty serve to promote an appreciation for diversity in our own community and more broadly. The Service Learning Elective (SLE) formally recognizes students deeply committed to their community, large and small. Moreover, the recently adopted School of Medicine Strategic Plan outlines several new avenues of outreach and service that will strengthen our ties with the community and hoefully enhance diversity within the school.

c. Based on your institution’s definition of diversity and the LCME standard that “schools should consider in their planning elements of diversity including, but not limited to, gender, racial, cultural and economic diversity,” report in the table below information regarding the percentage of enrolled students and employed faculty and staff in each of the categories included in your institution’s definition of diversity.


Category First Year Students

Male/Female(T = 186)

All Students

Male/Female(T = 713)

Faculty

Male/Female

Staff(define)*

Male/Female

Am. Indian/AK Native 0/0 0.14/0.00 0.18/0.00 0.00/0.19

Asian4.30/5.38 5.05/5.89 9.52/5.11 6.38/6.00

Black1.08/4.84 2.66/3.65 3.00/3.00 4.84/20.12

Hispanic2.69/2.15 2.10/1.40 5.47/2.12 0.39/3.48

Other Race or Unknown Race

2.15/2.153.23/1.40 N/A N/A

White45.70/29.57

44.04/30.43 47.97/23.63 15.28/43.33

Total Non-Disadvantaged

87.6386.4

Total Disadvantaged

12.3713.6

Also see standards ED-21 and MS-8.


APPENDIX FOR IS-1

STRATEGIC PLAN CONTRIBUTORSOrganizing CommitteeSteve Nelson, MDDean

Janis G. Letourneau, MDAssociate Dean for Faculty and Institutional Affairs

Wayne Backes, PhDAssociate Dean for Research

Keith SchrothAssociate Dean for Fiscal Affairs

Alan Burgener, MHAConsultant

Educational Enhancement WorkgroupRichard DiCarlo MD (Group Leader)Juzar Ali, MDJames Campbell, MDJoe Delcarpio, PhDRobin English, MDJimmy Falterman, MDCharles Hilton, MDRichard Howes, MDGeorge Karam, MDKim LeBlanc, MDW. Chapman Lee, MDFred Lopez, MDRobin McGoey, MDJohn Paige, MDRussell Russo, L-4Ryan Vega, L-2Richard Whitworth, PhD

Research Infrastructure and Core facilities Work GroupAlistair Ramsay, PhD (Group Leader)Ashok Aiyar, PhDDiego Aviles, MDWayne Backes, PhDEduardo Davila, PhDTimothy Foster, PhDArthur Haas, PhDDaniel Kapusta, PhDBen Kelly, PhDJay Kolls, MDKen Kratz, PhDRonald Luftig, PhDDavid Martin, MDCarol Mason, MDAugusto Ochoa, MD


Seth Pincus, MDJohnny Porter, PhDJudd Shellito, MDKurt Varner, PhD

Community Outreach and EngagementRobert Maupin, MD (Group Leader)Ceryl Lynn Besch, MDSean Collins, MDCharles Cefalu, MDErich Conrad, MDJohn England, MDDaniel Frey, MDCacky Hebert, MDEdward Helm, MDScott Nelson, L-4Frank Opelka, MDAlison Quayle, PhDHeidi Sinclair, MD

Faculty Development and MentoringPeter Winsauer, PhD (Group Leader)Nicolas Bazan, MD, PhDAndrew Catling, PhDSheila Chauvin, PhDStephania Cormier, PhDVin Dasa, MDPaula Gregory, PhDAmy Gutierrez, MDTonya Jagneaux, MDJanis Letourneau, MDMichael Levitzky, PhDBetty Lo, MDErich Richter, MDBo Sanders, MDKelly Sorrells, MDAnn Tilton, MDWayne Vedeckis, PhDDavid Welsh, MD

Clinical Centers of ExcellenceChristopher Baker, MD (Group Leader)Jack Andonie, MDDonald Bergsma, MDLeonard Bok, MDStephen Brierre, MDMichael Butler, MDFrank Culicchia, MDAlan Kaye, MDAndrew King, MDLee Nesbitt, MDThomas Nolan, MDJane OldsAlan Robson, MDPaul Rosenfeld, MDJoel SellersRicardo Sorensen, MD


Warren Summer, MDJ. Christopher Winters, MD

Communication StrategiesPatricia Molina, MD, PhD (Group Leader)Brian Barkemeyer, MDDaniel Barnhill, MDMartha Brewer, MDBennett DeBoisblanc, MDCathi Fontenot, MDAndrew Hollenbach, PhDStacey Holman, MDRussell Klein, MDChad LeingangJames Leonard, MDSam McClugage, PhDDaniel Nuss, MDHoward Osofsky, MDJack Strong, MDJudith Venuti, PhD


APPENDIX FOR IS-8

Approved: April 3, 2002

School of Medicine – Administrative Council CharterLSU Health Sciences Center in New OrleansPreamble

The leadership of the School of Medicine of the Louisiana State University Health Sciences Center in New Orleans (LSUHSC-NO), within rules, regulations, and policies of the School and Health Sciences Center, the LSU System, and the Board of Supervisors of the Louisiana State University and A & M College, do hereby effect through this Charter the Administrative Council of the School of Medicine (SOM).

Article I. Name.Section 1. This organization shall be known as the Administrative Council of the School of Medicine in

New Orleans, LSUHSC, hereinafter referred to as the Administrative Council.

Article II. Purpose.Section 1. To serve as a representative voice of the SOM leadership.Section 2. To provide a means of communication between the faculty, SOM leadership, and the Dean of

the SOM.A. To provide a means whereby the SOM leadership, through the Dean of the SOM, may refer

matters of common interest to a body representing the faculty or matters of interest or concern to the LSUHSC-NO administration.

B. To provide a means whereby the leadership can formally offer suggestions or recommendations to the Dean pertaining to matters of common interest. These matters include, but are not limited to, advanced faculty appointments, promotions and tenure, sabbatical requests, SOM policies and curriculum, ratification of medical graduates, and relationships with the LSUHSC Foundation and LSU HealthCare Network.

Section 3. To accept and share responsibility with the Dean of efforts to fulfill the mission of the SOM.

Article III. Membership and Term of Office.Section 1. Administrative Council shall be composed of a fixed core of voting members, comprised of the

Dean, the Associate and Assistant Deans, the Department Heads, the four elected representatives of the Faculty Assembly of the SOM, and the Directors of the Centers of Excellence upon the Dean’s designation.

Section 2. The Chancellor will also be appointed, as an ex officio member. Section 3. The Dean has the discretion to appoint other non-voting (ex officio) members to the

Administrative Council, including, but not limited to, the Vice-Chancellors, Dean Emeritus, Medical Director of Medical Center of Louisiana, Director of Libraries, President of the LSUHSC Foundation, Director of Information Services, and Chief Executive Officer of the LSU HealthCare Network.

Section 4. A Department Head can appoint a permanently designated, alternate representative to the Administrative Council; however, such alternate representatives are subject to the approval of the Dean. Alternate representatives must be senior faculty members of the department, must attend meetings on a regular basis and can vote in the absence of the Department Head on any matters before the Administrative Council.


Section 5. A simple quorum must be present for voting, either by secret, written ballot, show of hands, or voice vote.

Section 6. A favorable recommendation by the Administrative Council to the Dean requires a two-thirds majority vote.

Section 7. The term of office of a member of the Administrative Council will concur with the appointment status defining membership, except for elected representatives from the Faculty Assembly, whose terms are determined by the rules and bylaws of that organization.

Article IV. Meetings.Section 1. The Administrative Council shall meet in regular monthly sessions, with a minimum of 10

meetings held each year. The schedule will be set at the beginning of each calendar year and distributed to all members. The Dean may alter the dates of meetings as he may deem it necessary or advisable.

Section 2. Special meetings of the Administrative Council may be called.Section 3. Meetings will be governed by the Sturgis Standard Code of Parliamentary Procedures, latest

edition. Section 4. Meetings of the Administrative Council shall be open. Section 5. Some agenda items may require that the Administrative Council discuss and deliberate in

Executive Session. The Chairperson of the Administrative Council or presiding officer may call an Executive Session; any voting member of the Administrative Council may request an Executive Session that is approved by a simple majority vote of the members present.

Article V. Officers.Section 1. The Dean of the SOM shall be the Chairperson of the Administrative Council and shall

normally be the presiding officer. Section 2. The Associate Dean of Faculty and Institutional Affairs in the SOM shall be the Secretary of

the Administrative Council and shall be responsible for the agenda, minutes, and meeting calendar.

Section 3. The Chairperson of the Administrative Council, in his absence, may delegate the responsibility of presiding officer to any other voting member of the Administrative Council.

Article VI. Interpretation.Provisions of this Charter, whenever unclear, ambiguous, or indefinite, shall be subject to

interpretation by a two-thirds majority vote.


APPENDIX FOR IS-10

Full CV for Dean of the School of Medicine

CURRICULUM VITAE STEVE NELSON, M.D. C.M., F.C.C.P.

BIRTH DATE AND PLACE November 26, l952 New York City, New York

HOME ADDRESS 812 Bonfouca LaneMandeville, Louisiana 70471

EDUCATION PreMedical Training

Undergraduate1970-1974 SUNY at Stony Brook, Stony Brook, New York, BS Biology (Departmental

Honors)

Medical School1974-1978 Faculty of Medicine, McGill University, Montreal, Canada (University Scholar)

Postgraduate Training

l978-l979 Internship (Medicine), Johns Hopkins Hospital, Baltimore, MD

1979-1981 Residency (second year, Medicine), Johns Hopkins Hospital, Baltimore, MD

Residency (third year, Medicine), Johns Hopkins Hospital, Baltimore, MD

l981-l982 Clinical Fellowship in Pulmonary Medicine, Johns Hopkins Hospital, Baltimore, MD

1982-1984 Research Fellowship in Pulmonary Medicine, Johns Hopkins Hospital, Baltimore, MD

1982-1984 Fellowship in Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD


APPOINTMENTS OR POSITIONS:2007 – pres. Dean, Louisiana State University Health Sciences Center, New Orleans, LA

2006 - 2007. Program Director, GCRC, Tulane-LSU-Charity Hospital, New Orleans, LA

2005 – 2007 Section Chief, Pulmonary/Critical Care Medicine, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA

2005 – 2007 Vice Chair Research, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA

2003-2006 Associate Director, GCRC, Tulane-LSU-Charity Hospital, New Orleans, LA

2002- 2008 Director, Alcohol and Drug Abuse Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA

2002-pres. Professor of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA

2000-pres. Director, Alcohol Research Center, Louisiana State University Health Sciences Center, New Orleans, LA

1995-pres. John H. Seabury Professor of Medicine, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1994-pres. Professor of Medicine, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1994-pres. Professor of Physiology, Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1994-pres. Professor, School of Graduate Studies, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1994-pres. Clinical Professor of Medicine and Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana

1994-pres. Staff Physician, Section of Pulmonary/Critical Care Medicine, Ochsner Clinic and Hospital, New Orleans, Louisiana.

1990-1995 Director of Critical Care Units, University Hospital, New Orleans, Louisiana

1989-1994 Associate Professor, School of Graduate Studies, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1989-1994 Associate Professor of Medicine, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1989-1994 Associate Professor of Physiology, Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1989-1994 Clinical Associate Professor of Medicine and Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana


1988-2005 Director of Research Laboratories, Division of Pulmonary/Critical Care, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1985-1989 Clinical Assistant Professor of Medicine and Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana

1988-1989 Assistant Professor of Physiology, Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1985-pres. Associate Medical Staff, Tulane Medical Center, New Orleans, Louisiana

1985-1994 Consultant, Handicapped Children's Services Program (Cystic Fibrosis), Office of Preventive and Public Health Services, Department of Health and Human Resources, State of Louisiana

l984-1989 Assistant Professor of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana

1984-pres. Staff Physician, Division of Pulmonary/Critical Care, Charity Hospital of New Orleans, Louisiana

l984-pres. Staff Physician, Division of Pulmonary/Critical Care, University Hospital, New Orleans, Louisiana

1983-1984 Attending Physician, Medical Intensive Care Unit, Johns Hopkins Hospital, Baltimore, Maryland

CERTIFICATION:

Licentiate, Medical Council of Canada - l978Diplomate, National Board of Medical Examiners - 1979Diplomate, American Board of Internal Medicine - 1981FLEX - 1984Diplomate, American Board of Internal Medicine, Pulmonary Disease - 1986Diplomate, American Board of Internal Medicine, Critical Care Medicine - 1987

LICENSURE:

Maryland, 1981, D26487Louisiana, 1984, 06586R

AWARDS: 1972 Phi Beta Kappa, SUNY at Stony Brook1976-l978 Friends of McGill Scholarship, McGill University1976-1978 University Scholar, Faculty of Medicine, McGill University


1982-1984 School Scholarship, Johns Hopkins University, School of Hygiene and Public Health

1984 Physician's Recognition Award, American Medical Association1990 Alpha Omega Alpha Honor Medical Society, LSU Medical School1995 John H. Seabury Professorship1996 Best Doctors in America: Southeast Region1996 Southern Society for Clinical Investigation1998 Best Doctors in America2002 Best Doctors in America2002 Who’s Who in Medicine and Healthcare2003 Guide to America’s Top Physicians2003 Top Internists, New Orleans Magazine2003 Pfizer Award for Excellence in Research2004 Who’s Who in America2004-2006 Best Doctors in America2006 Who’s Who in Medicine and Healthcare2006 Edward C. Rosenow, III, Honor Lecture Award, American College of Chest

Physicians (for outstanding contributions to mentorship and training of chest physicians)

2007-2008 Best Doctors in America

GRANTS:

1981-1982 Fellowship in Adult Lung Diseases, American Lung Association1982-1984 National Research Service Award, NIH1984-1985 American Lung Association Research Award 1984-1987 Parker B. Francis Fellowship in Pulmonary Research, Puritan-Bennett

Foundation1986-1987 Research Award, Laerdal Foundation for Acute Medicine1988-1993 R29 NIAAA, “Effect of Alcoholism on TNF and Host Defense”, Principal

Investigator1989-1991 Research Award, National Cystic Fibrosis Foundation, “Cytokine-Induced

Inflammatory Lung Disease in CF”, Principal Investigator1990-1993 Research Award, Board of Regents, Louisiana Education Quality Support Fund,

“Sepsis-Induced Immune Dysfunction,” Co-Investigator1991-2000 AA08845, NIAAA, “Alcohol, Immunosuppression, and Pneumocystis carinii,”

Co-Investigator1992-1993 Research Award, AMGEN, Principal Investigator1992-pres. Consultant, AMGEN1993-2000 AA09803, NIAAA, Alcohol Research Center, “Alcohol, Infection, and

Host Response”, Associate Director and Principal Investigator1997-2002 AA11760, NIAAA, “Alcohol, TB, Host Defense,” Co-Investigator2000-2003 AA09803, NIAAA, Alcohol Research Center, “Alcohol, HIV Infection,

and Host Defense,” Director and Principal Investigator2000-2005 Board of Regents, Health Excellence Fund, “Center for Lung Biology and

Immunotherapy”, Co-Investigator2001-2008 AA13563, NIAAA, “The Effect of Alcohol on SIV Pathogenesis,” Co-

Investigator2001-2007 RR05096, NCRR, GCRC, Program Director2003-2007 AA14293, NIAAA, “Alcohol Research Planning and Development Program”,

Co-Investigator


2003-2009 AA09803, NIAAA, Comprehensive Alcohol Research Center, “Alcohol, HIV Infection, and Host Defense”, Director and Principal Investigator

2004-2009 AA11760, NIAAA, “Alcohol and Reactivation Tb”, Co-Investigator2005-2010 RR021970, NCRR, COBRE, Co-Investigator2007-2009 AA016118, NIAAA, “Alcohol Effects on Gene and Cytokine Expression of

Human Airway Epithelia”, Co-Investigator2007-2010 014RCEEP-07, Board of Regents, “Clinical and Translational Research

Education and Commercialization Program (CTRECP) at Tulane University and Louisiana State University Health Sciences Center”, Co-Principal Investigator

2007-2010 RCEEP-05 (2007-10), Board of Regents, “Development of a Nationally Recognized Model in Research Commercialization, Education and Workforce Development in Chemical Engineering and the Chemical Sciences through University and Community College Collaborations”, Project Director

2009-2010 AA017494, NIAAA, “Alcohol and Impairment of the Granulopoietic Response to Pneumonia”, Collaborator

SOCIETIES:

1974-pres. New York Academy of Sciences1981-pres. American College of Physicians1984-pres. American Medical Association1984-pres. American Society for Microbiology1984-pres. American Thoracic Society1985-pres. American Federation for Medical Research1986-pres. American College of Chest Physicians (Fellow)1989-pres. Research Society on Alcoholism1995-pres. Orleans Parish Medical Society2005-pres. Association of Professors of Medicine2008-pres. American Clinical and Climatological Association

COMMITTEES:

1985-1988 Charity Hospital AIDS Medical Advisory Committee1986-1999 LSU Medical Center Institutional Review Board1988-1990 Charity Hospital AIDS Research Committee1989-1995 Clinical Sciences Delegate, LSU Medical Center Faculty Assembly1989-1997 Animal Management Committee, LSU Medical Center1990-1996 Program Committee for the Scientific Assembly on Microbiology,

Tuberculosis, and Pulmonary Infections, American Thoracic Society1990-1992 Administrative Council of the Faculty Assembly, LSU Medical Center 1990-1995 Steering Committee, Section on Cardiopulmonary Infections, American

College of Chest Physicians 1991-1996 Steering Committee, Council on Critical Care, American College of Chest

Physicians1992-1995 American Medical Association CPT Advisory Committee1993-1995 Program Committee for the Scientific Assembly on Critical Care,

American Thoracic Society1993-1996 Annual International Scientific Program Committee, American College of Chest

Physicians


1994-1996 Program Committee Chairman, Scientific Assembly on Microbiology, Tuberculosis, and Pulmonary Infections, American Thoracic Society

1994-pres. Ad hoc Reviewer, NIAAA1997-2001 International Subcommittee, American College of Chest Physicians1997-1999 Long Range Planning Committee, Assembly on Microbiology, Tuberculosis, and

Pulmonary Infections, American Thoracic Society1998-2001 Research Advocacy Committee, American Thoracic Society1999-2001 Chairman, Nominating Committee (MTPI Assembly), American Thoracic

Society2000-2004 LSU Health Sciences Center MD/PhD Committee2002-pres. Executive Committee, Research Council, LSUHSC2003-pres. Tulane National Primate Research Center Resource Allocation Committee2006-pres. Board of Directors, LSU Healthcare Network2006-pres. Extramural Advisory Board (HIV-Related Biomedical Research), NIAAA

EDITORIAL BOARDS: Clinical Pulmonary Medicine 1995-present Mediguide to Pulmonary Medicine 1996-2001

Respiratory Medicine 1996-1998Nosocomial Infections 1997-2000Seminars in Respiratory and Critical Care Medicine 1998-presentAlcohol Research and Health (Journal of the 2006-present

National Institute on Alcohol Abuse and Alcoholism)International Journal of Clinical and Experimental 2007-present

Medicine

MANUSCRIPT REVIEW:

American Journal of Respiratory and Critical Care MedicineAmerican Journal of Respiratory Cell and Molecular BiologyChestClinical Infectious DiseasesJournal of Infectious DiseaseCritical Care MedicineJournal of Immunology

PUBLICATIONS

JOURNALS:

1. Nelson S, Carlson AD, and Copeland J: Mating-induced behavioral switch in female fireflies. Nature 255:628-629, 1975.

2. Nelson S, Prince D, and Terry P: Primary Hodgkin's disease of the lung. Thorax 38:3l0-311, 1983.

3. Wang K and Nelson S: Transbronchial needle aspiration of a mediastinal mass: therapeutic implications. Thorax 38:556- 557, 1983.


4. Nelson S, Summer W, and Jakab G: Aminophylline-induced suppression of pulmonary antibacterial defenses. Am Rev Respir Dis 131:923-927, 1985.

5. White J, Nelson S, Jakab G, and Lanser M: Methylprednisolone impairs the bactericidal activity of alveolar macrophages. J Surg Res 39:46-52, 1985.

6. White J, Nelson S, Winkelstein J, Booth F, and Jakab G: Impairment of antibacterial defense mechanisms of the lung by extrapulmonary infection. J Infect Dis 153:202-208, 1986.

7. Nelson S, Laughon B, Bartlett J, Summer W, and Jakab G: Characterization of the pulmonary inflammatory response to an anaerobic bacterial challenge. Am Rev Respir Dis 133:212-217, 1986.

8. Astry C, Nelson S, Karam G, and Summer W: Interactions of clindamycin with the antibacterial defenses of the lung. Am Rev Respir Dis 135:1015-1019, 1987.

9. Nelson S, Summer W, Terry P, Warr G, and Jakab G: Erythromycin suppresses pulmonary antibacterial defenses - A potential mechanism of superinfection in the lung. Am Rev Respir Dis 136:1207-1212, 1987.

10. Cosmo L, Risi G, Nelson S, Subramanian P, Martin D, and Haponik EF: Fatal hemoptysis in acute bacterial endocarditis. Am Rev Respir Dis 137:1223-1226, 1988.

11. Nelson S, Waring WW, and Summer WR: Cystic fibrosis in the young adult. Pulmonary and Critical Care Update 3 (19), 1988.

12. Nelson S, Chidiac C, and Summer WR: The pathogenesis and prevention of nosocomial pneumonia. J Crit Ill 3:12-24, 1988.

13. Summer WR and Nelson S: Severe community-acquired pneumonia. Pulmonary Perspectives 5 (2) Summer, 1988.

14. Herndandez OG, Nelson S, Haponik EF, Lopez A, and Summer WR: Obligate nasal breathing in an elderly woman: increased risk of nasogastric tube feeding. J Parent Enter Nutr 12:531-532, 1988.

15. Harris SE, Nelson S, Astry CL, Bainton BG, and Summer WR: Endotoxin-induced suppression of pulmonary antibacterial defenses against Staphylococcus aureus. Am Rev Respir Dis 138:1439-1443, 1988.

16. Cosmo L, Nelson S, Haponik E, Teaford T, and Summer WR: Nontraumatic hepatic diaphragmatic herniation: demonstration by computed chest tomography. J La State Medical Society 140:41-44, 1988.

17. Nelson S, Bagby GJ, Bainton BG, Wilson LA, Thompson JJ, and Summer WR: Compartmentalization of intraalveolar and systemic lipopolysaccharide- induced tumor necrosis factor and the pulmonary inflammatory response. J Infect Dis 159:189-194, 1989.

18. Summer WR, Curry P, Haponik EF, Nelson S, and Elston R: Continuous mechanical turning of ICU patients shortens length of stay in some diagnostic related groups. J Crit Care 4:45-53, 1989.


19. Summer WR, Elston R, Thorpe L, Nelson S, and Haponik EF: Aerosol bronchodilator delivery methods: relative impact on pulmonary function and cost of respiratory care. Arch Int Med 149:618-623, 1989.

20. Nelson S, Bagby G, and Summer WR: Alcohol suppresses lipopolysaccharide- induced tumor

necrosis factor activity in serum and lung. Life Sci 44:673-676, 1989.

21. Summer WR and Nelson S: Nosocomial pneumonia: Characteristics of the host-pathogen interaction. Respir Care 34:116-124, 1989.

22. D'Souza NB, Bagby GJ, Nelson S, Lang CH, and Spitzer JJ: Acute alcohol infusion suppresses endotoxin-induced tumor necrosis factor production. Alcohol Clin Exp Res 13:295-298, 1989.

23. Mahatma M, Haponik EF, Nelson S, Lopez A, and Summer WR: Phenytoin-induced acute respiratory failure with pulmonary eosinophilia. Am J Med 87:93-94, 1989.

24. Chidiac C, Nelson S, Summer WR, and Mouton Y: Experimental models of pneumonia. Pathol Biol 37:754-758, 1989.

25. Nelson S, Bagby GJ, Bainton BG, and Summer WR: The effects of acute and chronic alcoholism on tumor necrosis factor and the inflammatory response. J Infect Dis 160:422-429, 1989.

26. Bainton BG, Nelson S, Chidiac C, Bagby GJ, and Summer WR: Anti-inflammatory agents in sepsis and acute lung injury. Effects of methylprednisolone and ibuprofen on TNF and pulmonary host defenses. Critical Care Report 1:201-207, 1990.

27. Mason C, Nelson S, and Summer WR: Prevention of nosocomial pneumonia. J Emer Med 22:31-37, 1990.

28. Nelson S, Chidiac C, Bagby G, and Summer WR: Endotoxin-induced suppression of lung host defenses. J Med 21:85-103, 1990.

29. Mason C, Nelson S, and Summer W: Community-acquired pneumonia. Pulmonary Perspectives 7 (2) Summer, 1990.

30. Noel P, Nelson S, Bokulic R, Bagby G, Lippton H, Lipscomb G, and Summer W: Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality. Life Sci 47:1023-1029, 1990.

31. Bagby GJ, Plessala KJ, Wilson LA, Thompson JJ, and Nelson S: Divergent efficacy of

anti-TNFa antibody in intravascular and peritonitis models of sepsis. J Infect Dis 163:83-88, 1991.

32. Burlew BP, Noel P, and Nelson S: Local antibiotic therapy in bronchopulmonary infections. Critical Care Report 2:136-144, 1991.

33. Nelson S: The effects of thermal injury on systemic and pulmonary host defenses. Critical Care

Report 2:241-253, 1991.

34. Bagby GJ and Nelson S: The role of tumor necrosis factor in the host's response to infection. Critical Care Report 2:176-187, 1991.


35. Schuler A, Spolarics Z, Lang C, Bagby G, Nelson S, and Spitzer JJ: Upregulation of glucose metabolism by granulocyte-monocyte colony-stimulating factor. Life Sci 49:899-906, 1991.

36. Mahatma M, Agrawal N, Dajani EZ, Nelson S, Nakamura C, and Sitton J: Misoprostol but not antacid prevents endotoxin-induced gastric mucosal injury: role of tumor necrosis factor-alpha. Dig Dis Sci 36:1562-1568, 1991.

37. Nelson S, Bagby G, Nakamura C, Stewart L, Lipscomb G, Summer W, and Andresen J: Granulocyte colony-stimulating factor enhances pulmonary host defenses in normal and ethanol treated rats. J Infect Dis 164:901-906, 1991.

38. Spolarics Z, Schuler A, Bagby G, Lang C, Nelson S, and Spitzer J: In vivo metabolic response of hepatic nonparenchymal cells and leukocytes to granulocyte-macrophage colony-stimulating factor. J Leukoc Biol 51:360-365, 1992.

39. deBoisblanc BP, Meszaros K, Burns A, Bagby G, Nelson S, and Summer WR: Effect of dichloroacetate on mechanical performance and metabolism of compromised diaphragm muscle. J Appl Physiol 72:1149-1155, 1992.

40. Mason CM, Summer WR, and Nelson S: Pathophysiology of pulmonary defense mechanisms. J Crit Care 7:42-56, 1992.

41. Nakamura C, Nelson S, Lippton H, Bagby G, and Summer W: Contrasting effects of misoprostol on systemic and intrapulmonary lipopolysaccharide-induced tumor necrosis factor-alpha. Life Sci 50:1869-1876, 1992.

42. Lang CH, Bagby GJ, Dobrescu C, Nelson S, and Spitzer JJ: Effect of G-CSF on sepsis-induced changes on neutrophil accumulation and organ glucose uptake. J Infect Dis 166:336-343, 1992.

43. Shellito J, Nelson S, and Sorensen R: Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages. Infect Immun 60:3913-3915, 1992.

44. Akerman P, Cote P, Yang SQ, McClain C, Nelson S, Bagby GJ, and Diehl AM: Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. Am J Physiol 263:G579-585, 1992.

45. Lang CH, Bagby GJ, Dobrescu C, Nelson S, and Spitzer JJ: Modulation of the glucose metabolic response to endotoxin by granulocyte colony-stimulating factor. J Appl Physiol 263:R1122-1129, 1992.

46. Mason C, Dunn C, Kabir S, Nelson S, Summer W, and Dal Nogare AR: Gastrointestinal gram-negative colonization accompanies oropharyngeal colonization but is not adversely affected by elevation of gastric pH. J Crit Care 7:244-250, 1992.

47. Nelson S, Shellito J, Mason C, and Summer W: Alcohol and bacterial pneumonia. Alcohol Health and Research World 16:73-81, 1992.

48. Mason C and Nelson S: Normal host defenses and impairments associated with the delayed resolution of pneumonia. Semin Resp Infect 7:243-255, 1992.


49. Mason C, Nelson S, and Summer W: Bacterial colonization-pathogenesis and clinical significance. Immunol Allergy Clin North Am 13:93-108, 1993.

50. Greenberg SS, Xie J, Wang Y, Kolls J, Shellito J, Nelson S, and Summer W: Ethanol relaxes pulmonary artery by release of prostaglandin and nitric oxide. Alcohol 10:21-29, 1993.

51. Kolls J, Beck JM, Nelson S, Summer WR, and Shellito J: Alveolar macrophage release of tumor necrosis factor during murine Pneumocystis carinii pneumonia. Am J Respir Cell Mol Biol 8:370-376, 1993.

52. Kolls JK and Nelson S: The young adult with cystic fibrosis. Mediguide to Infectious Diseases 13:1-8, 1993.

53. Akerman PA, Cote PM, Yang SQ, McClain C, Nelson S, Bagby G, and Diehl AM: Long-term ethanol consumption alters the hepatic response to the regenerative effects of TNF-alpha. Hepatology 17:1066-1078, 1993.

54. Kolls JK, Nelson S, and Summer WR: Recombinant cytokines and pulmonary host defense: a review. Am J Med Sci 306:330-335, 1993.

55. Xie J, Wang Y, Lippton H, Cai BC, Nelson S, Kolls J, Summer WR, and Greenberg S: Tumor necrosis factor inhibits stimulated but not basal release of nitric oxide. Am Rev Respir Dis 148:627-636, 1993.

56. Greenberg S, Xie J, Wang Y, Cai B, Kolls J, Nelson S, Hyman A, Summer WR, and Lippton H: Tumor necrosis factor-alpha inhibits endothelial-dependent relaxation. J Appl Physiol 74:2394-2403, 1993.

57. Xie J, Wang Y, Kolls J, Malinski T, Nelson S, Summer W, and Greenberg S: Tumor necrosis factor-α inhibits contractions to sympathetic nerve stimulation by a nitric oxide-dependent mechanism. Proc Soc Exp Biol Med 203:446-453, 1993.

58. Kolls JK, Xie J, LeBlanc R, Malinski T, Nelson S, Summer WR, and Greenberg SS: Rapid induction of messenger RNA for nitric oxide synthase II in rat neutrophils in vivo by endotoxin and its suppression by prednisolone. Proc Soc Exp Biol Med 205:220-229, 1994.

59. Nelson S: Overview of granulocyte colony-stimulating factor in bacterial infections in the non-neutropenic host. Clin Infect Dis 18:197-204, 1994.

60. Tutor JD, Mason CM, Dobard E, Beckerman RC, Summer WR, and Nelson S: Loss of compartmentalization of alveolar tumor necrosis factor after lung injury. Am J Respir Crit Care Med 149:1107-1111, 1994.

61. Mason C, Nelson S, and Summer W: Bacterial translocation in the pathogenesis of pneumonia. Clin Pulm Med 1:215-222, 1994.

62. Greenberg S, Xie J, Wang Y, Kolls J, Malinski T, Summer W, and Nelson S: Ethanol suppresses LPS-induced mRNA for nitric oxide synthase II in alveolar macrophages in vivo and in vitro. Alcohol 11:539-547, 1994.

63. Daon E, Summer WR, Nelson S, and Mason CM: Cimetidine does not impair the pulmonary clearance of Pseudomonas aeruginosa in normal rats. Dig Dis Sci 39:1469-1472, 1994.


64. D'Souza NB, Nelson S, Summer WR, and Deaciuc IV: Expression of tumor necrosis factor-α and interleukin-6 cell-surface receptors of the alveolar macrophage in alcohol-treated rats. Alcohol Clin Exp Res 18:1430-1435, 1994.

65. Diehl AM, Yin M, Fleckenstein J, Yang SQ, Lin HZ, Brenner DA, Westwick J, Bagby G, and Nelson S: Tumor necrosis factor α induces c-jun during the regenerative response to liver injury. Am J Physiol 267:G552-G561, 1994.

66. D'Souza NB, Mandujano FJ, Nelson S, Summer WR, and Shellito JE: CD4+ T lymphocyte depletion attenuates LPS-induced TNF secretion by alveolar macrophages in the mouse. Lymphokine Cytokine Res 13:359-366, 1994.

67. King J, deBoisblanc BP, Mason CM, Onofrio JM, Lipscomb G, Mercante DE, Summer WR, and Nelson S: Effect of G-CSF on acute lung injury in the rat. Am J Respir Crit Care Med 151:302-309, 1995.

68. Nelson S, Mason C, Bagby G, and Summer W: Alcohol, tumor necrosis factor, and tuberculosis. Alcohol Clin Exp Res 19:17-24, 1995.

69. Adams LB, Mason CM, Kolls JK, Scollard D, Krahenbuhl JL, and Nelson S: Exacerbation of acute and chronic murine tuberculosis by administration of a TNF receptor-expressing adenovirus. J Infect Dis 171:400-405, 1995.

70. Greenberg S, Xie J, Kolls JK, Nelson S, Didier P, and Mason C: Ethanol supresses Mycobacteria tuberculosis-induced mRNA for nitric oxide synthase in alveolar macrophages, in vivo. Alcohol Clin Exp Res 19:394-401, 1995.

71. Mason CM, Kolls JK, and Nelson S: Pathogenesis and host defense in pulmonary infections. Current Opinion in Pulmonary Medicine 1:163-170, 1995.

72. Kolls JK, Lei D, Nelson S, Summer WR, Greenberg S, and Beutler B: Adenovirus-mediated blockade of tumor necrosis factor in mice protects against endotoxic shock yet impairs pulmonary host defense. J Infect Dis 171:570-575, 1995.

73. Kolls JK, Xie J, Lei D, Greenberg S, and Nelson S: Differential effects of in vivo ethanol on LPS-induced TNF and nitric oxide production in the lung. Am J Physiol 268: 991-998, 1995.

74. Mandujano JF, D'Souza NB, Nelson S, Summer WR, Beckerman RC, and Shellito JE:Granulocyte-macrophage colony-stimulating factor administration and Pneumocystis carinii pneumonia in mice. Am J Respir Crit Care Med 151:1233-1238, 1995.

75. Kolls JK, Nelson S, and Weinacker A: Gene therapy for lung diseases. Clin Pulm Med 2:238-243, 1995.

76. Dale DC, Liles WC, Summer WR, and Nelson S: Review: Granulocyte colony-stimulating factor (G-CSF): role and relationships in infectious diseases. J Infect Dis 172:1061-1075, 1995.

77. D'Souza NB, Mandujano F, Nelson S, Summer W and Shellito J: Alcohol ingestion impairs host defenses predisposing otherwise healthy mice to Pneumocystis carinii infection. Alcohol Clin Exp Res 19:1219-1225, 1995.


78. Diehl AM, Yang SQ, Yin M, Lin HZ, Nelson S, and Bagby G: Tumor necrosis factor-alpha modulates CCAAT/enhancer binding proteins-DNA binding activities and promotes hepatocyte-specific gene expression during liver regeneration. Hepatology 22:252-261, 1995.

79. D'Souza NB, Nelson S, Summer WR, and Deaciuc IV: Alcohol administration modulates alveolar macrophage tumor necrosis factor-α, superoxide anion and nitric oxide secretion in the rat. Alcohol Clin Exp Res 20:156-163, 1996.

80. deBoisblanc BP, Dobrescu C, Skrepnik N, Nelson S, Spitzer JJ, and Bagby GJ: Compartmentalization of glucose utilization after intravenous vs intratracheal challenge with lipopolysaccharide. Am J Physiol 270:L452-458, 1996.

81. Dunne JR, Dunkin BJ, Nelson S, and White JC: Effects of granulocyte colony-stimulating factor in a non-neutropenic rodent model of Escherichia coli peritonitis. J Surg Res 61:348-354, 1996.

82. Kolls JK, Lei D, Odom G, Nelson S, Summer WR, Gerber M, and Shellito J: Transient CD4-lymphocyte depletion prolongs transgene expression of E1-deleted adenoviral vectors. Human Gene Therapy 7:489-497, 1996.

83. Williams LM, Fussell S, Veith RW, Nelson S, and Mason C: Pulmonary veno-occlusive disease in an adult following bone marrow transplantation: case report and review of literature. Chest 109:1388-1391, 1996.

84. Summer RS, Summer WR, Kolls J, and Nelson S: Cytokines and pulmonary host defense. Clin Pulm Med 3:129-136, 1996.

85. Mason CM, and Nelson S: Pathophysiology of community-acquired pneumonia and treatment strategies based on host-pathogen interactions: the inflammatory interface. Sem Resp Crit Care Med 17:213-220, 1996.

86. Mason CM, Guery BPH, Summer WR, and Nelson S: Keratinocyte growth factor attenuates lung leak induced by alpha-naphthylthiourea in rats. Crit Care Med 24:925-931, 1996.

87. Daifuku R, Movahhed H, Fotheringham N, Bear M, and Nelson S: Time to resolution of morbidity: an endpoint for assessing the clinical cure of community-acquired pneumonia. Resp Med 90:587-592, 1996.

88. Lei D, Lehmann M, Shellito JE, Nelson S, Siegling A, Volk HD, and Kolls JK: Non-depleting anti-CD4 antibody treatment prolongs lung-directed E1-deleted adenovirus-mediated gene expression in rats. Human Gene Therapy 7:2273-2279, 1996.

89. Kolls JK, Lei D, Vasquez C, Odom G, Summer WR, Nelson S, and Shellito J: Exacerbation of murine Pneumocystis carinii infection by adenoviral-mediated gene transfer of a TNF inhibitor. Am J Respir Cell Mol Biol 16:112-118, 1997.

90. Guery BPH, Mason CM, Dobard EP, Beaucaire G, Summer WR, and Nelson S: Keratinocyte growth factor attenuates alphanaphthylthiourea-induced lung injury by increasing transalveolar sodium reabsorption. Am J Respir Crit Care Med 155:1777-1784, 1997.

91. Lei D, Lancaster JR, Joshi MS, Nelson S, Stoltz D, Bagby GJ, Odom G, Shellito JE, and Kolls JK: Activation of alveolar macrophages and lung host defenses using transfer of the interferon-gamma gene. Am J Physiol 272:L852-L859, 1997.


92. Nelson S: (panel member). From the bench to the bedside: the future of sepsis research. Executive Summary of an American College of Chest Physicians, National Institute of Allergy and Infectious Disease, and National Heart, Lung, and Blood Institute Workshop. Chest 111:744-753, 1997.

93. Kolls JK, Lei D, Nelson S, Summer WR, and Shellito JE: Pulmonary cytokine gene therapy. Adenoviral-mediated murine interferon gene transfer compartmentally activates alveolar macrophages and enhances bacterial clearance. Chest 111:104S, 1997.

94. Zhang P, Bagby GJ, Stoltz DA, Spitzer JA, Summer WR, and Nelson S: Modulation of the lung host response by granulocyte colony-stimulating factor in rats challenged with intrapulmonary endotoxin. Shock 7:193-199, 1997.

95. deBoisblanc BP, Mason CM, Andresen J, Logan E, Bear MB, Johnson S, Shellito J, Summer WR, and Nelson S: Phase 1 Safety Trial of Filgrastim (r-metHuG-CSF) in non-neutropenic patients with severe community-acquired pneumonia. Resp Med 91:387-394, 1997.

96. Stoltz DA, Bagby GJ, and Nelson S: Use of G-CSF in the treatment of acute infectious diseases. Current Opinion Hematol 4:207-212, 1997

97. Zhang P, Nelson S, Summer W, and Spitzer JA: Acute ethanol intoxication suppresses the pulmonary inflammatory response in rats challenged with intrapulmonary endotoxin. Alcohol Clin Exp Res 21:773-778, 1997.

98. Skerrett SJ, Bagby G, Schmidt R, and Nelson S: Antibody-mediated depletion of tumor necrosis factor-α impairs pulmonary host defenses to Legionella pneumophila. J Infect Dis 176:1019-1028, 1997.

99. Mason CM, Nelson S, Dobard E, and Summer WR: Intraportal lipopolysaccharide suppresses pulmonary antibacterial defense mechanisms. J Infect Dis 176:1293-1302, 1997.

100. Zhang P, Bagby GJ, Stoltz DA, Summer WR, and Nelson S: Enhancement of peritoneal leukocyte function by granulocyte colony-stimulating factor in rats with abdominal sepsis. Crit Care Med 26:315-321, 1998.

101. Zhang P, Bagby GJ, Xie M, Stoltz DA, Summer WR, and Nelson S: Acute ethanol intoxication inhibits neutrophil β2-integrin expression in rats during endotoxemia. Alcohol Clin Exp Res 22:135-141, 1998.

102. Kolls JK, Lei D, Stoltz D, Zhang P, Schwarzenberger PO, Ye P, Bagby G, Summer WR, Shellito JE, and Nelson S: Adenoviral-mediated interferon-gamma gene therapy augments pulmonary host defense of ethanol treated rats. Alcohol Clin Exp Res 22:157-162, 1998.

103. Guery B, deBoisblanc B, Fialdes P, Sarphy TG, Nelson S, Chidiac C, Beaucaire G, Summer WR and Mason CM: Pulmonary stress injury within physiological ranges of airway and vascular pressures. J Crit Care 13:58-66, 1998.

104. Omidvari K, Casey R, Nelson S, Olariu R, and Shellito J: Alveolar macrophage release of tumor necrosis factor-α in chronic alcoholics without liver disease. Alcohol Clin Exp Res 22:567-572, 1998.


105. Bagby GJ, Stoltz, DA, Zhang P, Bohm RP, and Nelson S: SIV infection, alcohol and host defense. Alcohol Clin Exp Res 22:193S-195S, 1998.

106. Prakash O, Joshi BH, Zhang P, Aw TY, Teng S, Ali M, Shellito JE and Nelson S: Transgenic mouse model of ethanol as a cofactor in HIV disease. Alcohol Clin Exp Res 22:266S-268S, 1998.

107. Nelson S, Belknap SM, Carlson RW, Dale D, deBoisblanc B, Farkas S, Fotheringham N, Ho H, Marrie T, Movahhed H, Root R, and Wilson J: A randomized controlled trial of filgrastim as an adjunct to antibiotics for treatment of hospitalized patients with community-acquired pneumonia (CAP). J Infect Dis 178:1075-1080, 1998.

108. Nelson S and Summer WR: Innate immunity, cytokines, and pulmonary host defense. Infect Dis Clin of North Am 12:555-567, 1998.

109. Guery B, Nelson S, Viget N, Fialdes P, Summer WR, Dobard E, Beaucaire G, and Mason CM: Fluorescein-labeled dextran concentration is increased in BAL fluid after ANTU-induced edema in rats. J Appl Physiol 85:842-848, 1998.

110. Mason CM, Dobard E, Kolls J, and Nelson S: The effect of alcohol on bacterial translocation in rats. Alcohol Clin Exp Res 22:1640-1645, 1998.

111. Prakash O, Zhang P, Xie M, Ali M, Zhou P, Coleman R, Stoltz DA, Bagby GJ, Shellito JE, and Nelson S: The human immunodeficiency virus type 1 tat protein potentiates ethanol-induced neutrophil functional impairment in transgenic mice. Alcohol Clin Exp Res 22:2043-2049, 1998.

112. Bagby GJ, Zhang P, Stoltz DA, and Nelson S: Suppression of the G-CSF response to E. coli challenge by alcohol intoxication. Alcohol Clin Exp Res 22:1740-1745, 1998.

113. Omidvari K, deBoisblanc BP, Karam G, Nelson S, Haponik E, and Summer W: Early transition to oral antibiotic therapy for community-acquired pneumonia: duration of therapy, clinical outcomes, and cost analysis. Resp Med 92:1032-1039, 1998.

114. Morrow SL, Larson JE, Nelson S, Ren T, and Cohen JC: Modification of development by the CFTR gene in utero: evidence for a secretory cell missing (scm) activity. Mol Med Metabolism 65:203-212, 1998.

115. Schwarzenberger P, LaRussa V, Miller A, Ye P, Huang W, Zieske A, Nelson S, Bagby G, Stoltz D, Mynatt R, Spriggs M, and Kolls JK: Interleukin 17 stimulates granulopoiesis in mice: use of an alternate, novel, gene therapy derived method for in vivo evaluation of cytokines. J Immunol 161:6383-6389, 1998.

116. Zhang P, Bagby GJ, Stoltz DA, Summer WR, and Nelson S: G-CSF modulates the pulmonary host response to endotoxin in the absence and presence of ethanol intoxication. J Infect Dis 179:1441-1448, 1999.


117. Greenberg S, Zhao X, Hua L, Wang JF, Nelson S, and Ouyang J: Ethanol inhibits lung clearance of Pseudomomas aeruginosa by a neutrophil and nitric oxide dependent mechanism, in vivo. Alcohol Clin Exp Res 23:735-744, 1999.

118. Stoltz DA, Zhang P, Nelson S, Bohm RP Jr, Murphey-Corb M, and Bagby GB:

Ethanol suppression of the functional state of polymorphonnuclear leukocytes obtained from uninfected and simian immunodeficiency virus infected rhesus macaques. Alcohol Clin Exp Res 23:878-884, 1999.

119. Kolls JK, Habetz S, Shean MK, Vazquez C, Brown JA, Lei D, Schwarzenberger P, Ye P, Nelson S, Summer WR, and Shellito, JE: Interferon-gamma and CD8+ T-cells restore host defenses against P. carinii in mice lacking CD4+ T-cells. J Immunol 162:2890-2894, 1999.

120. Nelson S. A question of balance (Editorial). Am J Respir Crit Care Med 159:1365- 1367, 1999.

121. Mason CM and Nelson S: Pulmonary host defenses: Implications for therapy. Clin Chest Med 20:475-488, 1999.

122. Greenberg SS, Ouyang J, Zhao X, Parrish C, Nelson S, and Giles TD: Effects

of ethanol on neutrophil recruitment and lung host defense in nitric oxide synthase I and nitric oxide synthase II knockout mice. Alcohol Clin Exp Res 23:1435-1445, 1999.

123. Zhang P, Nelson S, Summer W, and Spitzer JA: Serine/threonine phosphorylation mediates the phagocytic response of alveolar macrophages in rats challenged with intratracheal endotoxin. Shock 13:34-40, 2000.

124. Stoltz DA, Nelson S, Kolls JK, Zhang P, Bohm RP, Jr., Murphey-Corb M, and Bagby GJ: In vitro ethanol suppresses alveolar macrophage TNF-α during simian immunodeficiency virus infection. Am J Respir Crit Care Med 161:135-140, 2000.

125. Hunt JD, Robert EG, Zieske AW, Bautista AP, Bukara M, Lei D, Shellito JE, Nelson S, Kolls JK, and Skrepnik N: Orthotopic human lung cancer xenografts in BALB/c mice immunosuppressed with anti-CD4 monoclonal antibodies and chronic alcohol comsumption. Cancer 88:468-479, 2000.

126. Nelson S, Summer WR, and Mason CM: The role of the inflammatory response in chronic bronchitis: therapeutic implications. Sem Respir Infect 15:24-31, 2000.

127. Zhang Z, Cork J, Ye P, Lei D, Schwarzenberger PO, Summer WR, Shellito JE, Nelson S, and Kolls JK: Inhibition of TNF-α processing and TACE-mediated ectodomain shedding by ethanol. J Leukoc Biol 67:856-862, 2000.

128. Rodriguez FH, Nelson S, and Kolls JK: Cytokine therapeutics for infectious diseases. Curr Pharm Des 6:665-680, 2000.

129. Mason CM, Dobard E, Kolls JK, and Nelson S: Ethanol and murine interleukin (IL)-12 production. Alcohol Clin Exp Res 24:553-559, 2000.


130. Zhang P, Summer WR, Bagby GJ, and Nelson S: Innate immunity and pulmonary host defense. Immunol Rev 173:39-51, 2000.

131. Schwarzenberger P, Huang W, Ye P, Oliver P, Manuel M, Zhang Z, Bagby G, Nelson S, and Kolls JK: Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J Immunol 164:4783-4789, 2000.

132. Welsh DA, Summer WR, Dobard EP, Nelson S, and Mason CM: Keratinocyte growth factor prevents ventilator-induced lung injury in an ex vivo rat model. Am J Respir Crit Care Med 162:1081-1086, 2000.

133. Nelson S and Mason CM: The inflammatory response in chronic bronchitis. Sem Respir Crit Care Med 21:79-86, 2000.

134. Nelson S, Heyder AM, Stone J, Bergeron MG, Daugherty S, Peterson G, Fotheringham N, Welch W, Milwee S, and Root R: A randomized controlled trial of filgrastim for the treatment of hospitalized patients with multilobar pneumonia. J Infect Dis 182:970-973, 2000.

135. Kolls JK and Nelson S: Immune modulation in the treatment of respiratory infection. Respir Res 1:9-11, 2000.

136. Zhang P, Bagby GJ, Kolls JK, Summer WR, Andresen J, and Nelson S: The effects of granulocyte colony-stimulating factor and neutrophil recruitment on the pulmonary chemokine response to intratracheal endotoxin. J Immunol 165:458-465, 2001.

137. Nelson S, Bagby GJ, and Dale D: Cytokine treatment of bacterial pneumonia. Sem

Respir Infect 16:38-46, 2001.

138. Welsh DA, Guery BPH, DeBoisblanc BP, Dobard E, Creusy C, Mercante D, Nelson S, Summer WR, and Mason CM: Keratinocyte growth factor attenuates hydrostatic pulmonary edema in an isolated, perfused rat lung model. Am J Physiol 280:H1311-H1317, 2001.

139. Wunderink RG, Leeper K, Schein R, Nelson S, DeBoisblanc BP, Fotheringham N, and Logan E: Filgrastim in patients with pneumonia and severe sepsis or septic shock. Chest 119:523-529, 2001.

140. Prakash O, Rodriguez VE, Tang ZY, Zhou P, Coleman R, Dhillon G, Shellito JE, and Nelson S: Inhibition of hematopoietic progenitor cell proliferation by ethanol in human immunodeficiency virus type 1 Tat-expressing transgenic mice. Alcohol Clin Exp Res 25:450-456, 2001.

141. Boé DM, Nelson S, Zhang P, and Bagby GJ: Acute ethanol intoxication suppresses lung chemokine production following infection with Streptococcus pneumoniae. J Infect Dis 184:1134-1142, 2001.


142. Ye P, Garvey PB, Zhang P, Nelson S, Bagby G, Summer WR, Schwarzenberger P, Shellito JE, and Kolls JK: Interleukin-17 and lung host defense against Klebsiella pneumoniae infection. Am J Respir Cell Mol Biol 25:335-340, 2001.

143. Ye P, Rodriguez FH, Kanaly S, Stocking KL, Schurr J, Schwarzenberger P, Oliver P, Huang W, Zhang P, Zhang J, Shellito JE, Bagby GJ, Nelson S, Charrier K, Perscho JJ, and Kolls JK: Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment and host defense. J Exp Med 194:519-528, 2001.

144. Nelson S: Novel nonantibiotic therapies for pneumonia: cytokines and host defense. Chest 119:419S-425S, 2001.

145. Mason CM, Dobard E, Shellito J, and Nelson S: CD4+ lymphocyte responses to pulmonary infection with Mycobacterium tuberculosis in naïve and vaccinated BALB/c mice. Tuberculosis 81:327-334, 2001.

146. Zhang P, Bagby GJ, Boe DM, Zhong Q, Schwarzenberger P, Kolls JK, Summer WR, and Nelson S: Acute alcohol intoxication suppresses the CXC chemokine response during endotoxemia. Alcohol Clin Exp Res 26:65-73, 2002.

147. Zhang P, Nelson S, Holmes MC, Summer WR, and Bagby GJ: Compartmentalization of macrophage inflammatory protein-2, but not cytokine-induced neutrophil chemoattractant, in rats challenged with intratracheal endotoxin. Shock 17:104-108, 2002.

148. Stoltz DA, Nelson S, Kolls JK, Zhang P, Bohm RP Jr, Murphey-Corb M, and Bagby GJ: Effects of in vitro ethanol on tumor necrosis factor-alpha production by blood obtained from SIV infected rhesus macaques. Alcohol Clin Exp Res 26:527-534, 2002.

149. Quinton LJ, Nelson S, Boe DM, Zhang P, Zhong Q, Kolls JK, and Bagby GJ: The granulocyte colony-stimulating factor response following intrapulmonary and systemic bacterial challenges. J Infect Dis 185:1476-1482, 2002.

150. Prakash O, Tang ZY, Zhou P, Peng X, Kolls J, Shellito J, and Nelson S: Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line. Alcohol Clin Exp Res 26:295-302, 2002.

151. Nelson S and Kolls JK: Alcohol, host defense and society. Nature Rev Immunol 2:205-209, 2002.

152. Zhang P, Bagby GJ, Happel KI, Summer WR, and Nelson S: Pulmonary host defenses and alcohol. Front Biosci 7:d1314-1330, 2002.

153. Nelson S: Alcohol and bacterial pneumonia. J Resp Dis 23:326-328, 2002.

154. Holmes MC, Zhang P, Nelson S, Summer WR, and Bagby GJ: Neutrophil modulation of the pulmonary chemokine response to lipopolysaccharide. Shock 18:555-560, 2002.

155. Winsauer PJ, Moerschbaecher JM, Brauner I, Lancaster JR, Bagby GJ, and Nelson S: Alcohol unmasks SIV-induced cognitive impairments in rhesus monkeys. Alcohol Clin Exp Res 26:1846-1857, 2002.


156. Spitzer JA, Zhang P, Bagby GJ, Stowe CV, and Nelson S: Sex differences in the modulation by ethanol of lung chemotaxis. Alcohol 28:95-102, 2002.

157. Prakash O and Nelson S: Alcohol and liver disease. The Ochsner J 4:241-244, 2002.

158. Root RK, Lodato RF, Ward P, Cade JF, Fotheringham N, Milwee S, Vincent JL, Torres A, Rello J, and Nelson S: Multicenter, double-blind, placebo-controlled study of the use of filgrastim in patients hospitalized with pneumonia and severe sepsis. Crit Care Med 31:367-373, 2003.

159. Zhang P, Quinton LJ, Bagby GJ, Summer WR, and Nelson S: Interferon-gamma enhances the pulmonary CXC chemokine response to intratracheal lipopolysaccaride challenge. J Infect Dis 187:62-69, 2003.

160. Zhao X-J, Marrero L, Song K, Oliver P, Chin SY, Simon H, Schurr JR, Zhang Z, Thoppil D, Lee S, Nelson S, and Kolls JK: Acute alcohol inhibits TNF-alpha processing in human monocytes by inhibiting TNF/TACE interactions in the cell membrane. J Immunol 170:2923-2931, 2003.

161. Bagby GJ, Stoltz DA, Zhang P, Kolls JK, Brown J, Bohm, Jr. RP, Rockar R, Purcell J, Murphey-Corb M, and Nelson S: The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques. Alcohol Clin Exp Res 27:495-502, 2003.

162. Molina PE, Hoek JB, Nelson S, Guidot DM Lang CH, Wands JR, and Crawford JM: Mechanisms of alcohol-induced tissue injury. Alcohol Clin Exp Res 27:563-575, 2003.

163. Happel KI, Zheng M, Quinton LJ, Lockhart E, Ramsay AJ, Shellito JE, Schurr JR, Bagby GJ, Nelson S, and Kolls JK: Cutting edge: roles of toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J Immunol 170:4432-4436, 2003.

164. Boe DM, Nelson S, Zhang P, Quinton L, and Bagby GJ: Alcohol-induced suppression of lung chemokine production and the host defense response to Streptococcus pneumoniae. Alcohol Clin Exp Res 27:1838-1845, 2003

165. Quinton LJ, Nelson S, Zhang P, Boe DM, Happel KI, Pan W, and Bagby GJ: Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol 286: L465-L472, 2004.

166. Happel KI, Bagby GJ, and Nelson S: Host defense and bacterial pneumonia. Semin Respir Crit Care Med 25:43-52, 2004.

167. Mason CM, Dobard E, Zhang P, and Nelson, S: Alcohol exacerbates murine pulmonary tuberculosis. Infect Immun 72:2556-2563, 2004.

168. Shahbazian LM, Quinton, LJ, Bagby GJ, Nelson S, Wang G, and Zhang P: Escherichia coli pneumonia enhances granulopoiesis and the mobilization of myeloid progenitor cells into the systemic circulation. Crit Care Med 32:1740-1746, 2004.

169. Happel KI, Nelson S, and Summer WR: The lung in sepsis: fueling the fire. Am J Med Sci 328:230-237, 2004.


170. Mason CM and Nelson S: Pulmonary host defenses and factors predisposing to lung infection. Clin Chest Med 26:11-17, 2005

171. Zhang P, Quinton LJ, Gamble L, Bagby GJ, Summer WR, and Nelson S: The granulopoietic cytokine response and enhancement of granulopoiesis in mice during endotoxemia. Shock 23:344-352, 2005.

172. Quinton LJ, Nelson S, Zhang P, Happel KI, Gamble L, and Bagby GJ: Effects of systemic and local CXC chemokine administration on the ethanol-induced suppression of pulmonary neutrophil recruitment. Alcohol Clin Exp Res 29:1198-1205, 2005.

173. Happel KI, Lockhart EA, Mason CM, Poretta E, Keoshkerian E, Odden AR, Nelson S and Ramsay AJ: Pulmonary IL-23 gene delivery increases local T cell immunity and controls growth of Mycobacterium tuberculosis in the lungs. Infect Immun 73:5782-5788, 2005.

174. Happel KI, Dubin PJ, Zheng M, Ghilardi N, Lockhart C, Quinton LJ, Odden AR, Shellito JE, Bagby GJ, Nelson S, and Kolls JK: Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J Exp Med 202:761-769, 2005.

175. Song, K, Zhao XJ, Marrero L, Oliver P, Nelson S, and Kolls JK: Alcohol reversibly disrupts TNF-alpha-TACE interactions in the cell membrane. Respir Res 6:123-131, 2005.

176. Happel KI and Nelson S: Alcohol, immunosuppression, and the lung. Proc Am Thorac Soc 2:428-432, 2005.

177. Poonia B, Nelson S, Bagby GJ, Zhang P, Quinton L, and Veazey RS: Chronic alcohol consumption results in higher simian immunodeficiency virus replication in mucosally inoculated rhesus macaques. AIDS Res Hum Retroviruses 21:863-868, 2005.

178. Gamble, L, Mason CM, and Nelson S: The effects of alcohol on immunity and bacterial infection in the lung. Med Mal Infect 36: 72-77, 2006.

179. Happel KI, Odden AR, Zhang P, Shellito JE, Bagby GJ, and Nelson S: Acute alcohol intoxication suppresses the interleukin 23 response to Klebsiella pneumoniae infection. Alcohol Clin Exp Res 30:1200-1207, 2006.

180. Philipp MT, Purcell JE, Martin DS, Buck WR, Plauche GB, Ribka EP, DeNoel P, Hermand P, Leiva LE, Bagby GJ, and Nelson S: Experimental infection of rhesus macaques with Streptococcus pneumoniae: a possible model for vaccine assessment. J Med Primatol 35:113-122, 2006.

181. Poonia B, Nelson S, Bagby GJ, and Veazey RS: Intestinal lymphocyte subsets and turnover are affected by chronic alcohol consumption: implications for SIV/HIV infection. J Acquir Immune Defic Syndro 41:537-547, 2006.

182. Bagby GJ, Zhang P, Purcell J, Didier PJ, and Nelson S: Chronic binge ethanol consumption accelerates progression of SIV Disease. Alcohol Clin Exp Res 30:1781-1790, 2006.

183. Molina PE, McNurlan M, Rathmacher J, Lang CH, Zambell KL, Purcell J, Bohm RP, ZhangP, Bagby GJ, and Nelson S: Chronic alcohol accentuates nutritional, metabolic, and immune alterations during asymptomatic simian immunodeficiency virus infection. Alcohol Clin Exp Res 30:2065-2078, 2006.


184. Zhang P, Zhong Q, Bagby GJ, and Nelson S: Alcohol intoxication inhibits pulmonary S100A8 and S100A9 expression in rats challenged with intratracheal lipopolysaccharide. Alcohol Clin Exp Res 31:113-121, 2007.

185. Mason CM, Porretta E, Zhang P, and Nelson S: CD4+ CD25+ transforming growth factor-β-producing T cells are present in the lung in murine tuberculosis and may regulate the host inflammatory response. Clin Exp Immunol 148:537-545, 2007.

186. Happel KI, Rudner X, Quinton LJ, Movassaghi M, Clark C, Odden AR, Zhang P, Bagby GJ, Nelson S, and Shellito JE: Acute alcohol intoxication suppresses the pulmonary ELR-negative CXC chemokine response to lipopolysaccharide. Alcohol 41:325-333, 2007.

187. Dufour J, Ooms TG, Phillippi-Falkenstein KM, Penney T, Doyle L, Bagby GJ, Nelson S, Veazey RS, and Bohm RP Jr. Complications of gastric catheters implanted in rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 46: 29-34, 2007.

188. Molina PE, Lang CH, McNurlan M, Bagby GJ, and Nelson S: Chronic alcohol accentuates simian acquired immunodeficiency syndrome-associated wasting. Alcohol Clin Exp Res 32:138-147, 2008.

189. Zhang P, Bagby GJ, Happel KI, Raasch CE, and Nelson S: Alcohol abuse, immunosuppression, and pulmonary infection. Current Drug Abuse Reviews 1:56-67, 2008.

190. Siggins RW II, Zhang P, Welsh DA, LeCapitaine NJ, and Nelson S: Stem cells, phenotypic inversion, and differentiation. Int J Clin Exp Med 1:2-21, 2008.

191. Zhang P, Welsh DA, and Nelson S: The hematopoietic stem cell response to Escherichia Coli bacteremia. In Press, Crit Care Med, 2008.

192. Zhang P, Nelson S, Bagby GJ, Siggins RW II, Shellito JE, and Welsh DA: The lineage-c-kit+Sca-1+ cell response to Escherichia Coli Bacteremia in Balb/c mice. Stem Cells 26:1778-1786, 2008.

193. Hajishengallis G, Wang M, Bagby GJ, and Nelson S: Importance of TLR2 in early innate immune response to acute pulmonary infection with Porphyromonas gingivalis in mice. J Immunology 181:4141-4149, 2008.

194. Gamble L, Bagby GJ, Quinton LJ, Happel KI, Mizgerd JP, Zhang P, and Nelson S: The systemic and pulmonary lipopolysaccharide binding protein response to intratracheal lipopolysaccharide. Shock 31:212-217, 2008.

195. Walker Jr JE, Odden AR, Jeyaseelan S, Zhang P, Bagby GJ, Nelson S, and Happel KI: Ethanol exposure impairs LPS-Induced Pulmonary LIX expression: alveolar epithelial cell dysfunction as a consequence of acute intoxication. Published Online: Alcohol Clin Exp Res, Nov, 2008.

196. Zhang P, Welsh DA, Siggins RW II, Bagby GJ, Raasch CE, Happel KI, and Nelson S: Acute alcohol intoxication inhibits the Lineage-c-kit+Sca-1+ cell response to Escherichia coli Bacteremia. J Immunology 182:1568-1576, 2009.

BOOKS/MONOGRAPHS:


1. Contemporary Issues in Pulmonary Infections. (P. Cole, S. Nasraway, and S. Nelson., eds). Chest: 108, 1995.

2. Future of Sepsis Research. (R. Phillip Dellinger, Chairman). ACCP, NIAID, and NHLBI Conference Proceedings. Division of Health and Science Policy, ACCP, 1997.

3. Cytokines and Pulmonary Infection. Part I: Host-Pathogen Interactions in Pulmonary Infection (S. Nelson, ed). American Thoracic Society, 1997.

4. Cytokines and Pulmonary Infection. Part II: The Role of Cytokines in Systemic and Pulmonary Medicine (S. Nelson, ed). American Thoracic Society, 1997.

5. Cytokines and Pulmonary Infection. Part III: The Economics and Targets of New Therapies in Pulmonary Infections. (S. Nelson, ed) American Thoracic Society, 1998.

6. Cytokines in Pulmonary Disease. Infection and Inflammation. (S. Nelson and T. Martin, eds). Marcel Dekker, Inc, New York, 2000.

7. Pulmonary Host Defenses (S. Nelson and T. Standiford, eds). Sem Resp Crit Care Med Vol. 25. Thieme, New York, 2004.

CHAPTERS:

1. Nelson S, Summer WR, Jakab GJ: Aminophylline-induced suppression of pulmonary antibacterial defenses. In, The Year Book of Pulmonary Disease (G.M. Green, W.C. Ball, H.A. Menkes, J.R. Michael, S.P. Peters, P.B. Terry, M.S. Tockman, and R. Wise, eds). Year Book Medical Publishers, Inc.,1986.

2. Nelson S, Bagby GJ, Summer WR: Alcohol-induced suppression of tumor necrosis factor - a potential risk factor for secondary infection in the acquired immunodeficiency syndrome. In, Alcohol, Immunosuppression and AIDS (D. Seminara, R. Watson, and A. Pawlowski, eds). Alan R. Liss, Inc.,1990.

3. Nelson S: Pulmonary host defenses in burn injury. In, Respiratory Complications In Thermal Injury (E.F. Haponik and A.M. Munster, eds). McGraw-Hill Book Company, 1990.

4. Nelson S, Summer WR, Bagby GJ: LPS-induced inhibition of lung TNF and host defenses. In, The Physiological and Pathological Effects of Cytokines. (C. A. Dinarello, M.J. Kluger, M.C. Powanda and J.J. Oppenheim, eds). Wiley-Liss, Inc., 1990.

5. Nelson S, Summer WR: The adverse effects of pharmacologic therapy on pulmonary host defenses. In, Respiratory Disease in the Immunosuppressed Host (J. Shelhamer, P.A. Pizzo, J.E. Parillo and H. Masur, eds). J.B. Lippincott and Company, 1991.

6. Nelson S, Bagby G, Andresen J, Nakamura C, Shellito J, Summer WR: The effects of ethanol, tumor necrosis factor, and granulocyte colony-stimulating factor on lung antibacterial defenses. In, Drugs of Abuse, Immunity, and Immunodeficiency. (H. Friedman, ed.) Plenum Press, 1991.

7. Nelson S, Mason C, Nakamura C, Bagby G: The role of tumor necrosis factor in health and disease. In, Alcohol, Immunity and Cancer. (R. Yirmiya and A.Taylor, eds.) CRC Press, 1992.


8. Nelson S, Diafuku R, Andresen J: Granulocyte colony-stimulating factor in infectious diseases. In, Granulocyte Colony-Stimulating Factor in Clinical Practice. (G. Morstyn and M. Dexter, eds). Marcel Dekker, Inc, 1993.

9. Nelson S, Summer W: New strategies in the therapy of sepsis and pneumonia. In, Respiratory Infections. (M. Neiderman, G. Sarosi, and J. Glassroth, eds) W.B. Saunders Company, 1994.

10. Nelson S, Mason C, Kolls J, Summer WR: Pathophysiology of pneumonia. In, Pneumonia in the Intensive Care Unit. (R. Wunderink, ed). W. B. Saunders Company, 1995.

11. Kolls, JK, Mason CM, Nelson S: Effect of ethanol on tumor necrosis factor and cytokine production in lung antibacterial defenses. In, Drugs of Abuse and the Immune Response. (H. Friedman, T. Klein, and S. Specter, eds). CRC Press, 1995.

12. Nelson S, Bagby G: Granulocyte colony-stimulating factor and modulation of inflammatory cells in sepsis. In, The Sepsis Syndrome. (P. Dorinsky, ed). W.B. Saunders Company, 1996.

13. Weinacker A, Nelson S: Pneumonia prevention. In, Pulmonary Secrets. (P. Parsons and J. Heffner, eds). Hanley and Belfus, Inc, 1997.

14. Morstyn G, Foote MA, Nelson S: Clinical benefits of improving host defences with rHuG-CSF. In, The Molecular Basis of Cellular Defence Mechanisms. Ciba Foundation Symposium 204. John Wiley and Sons, 1997.

15. deBoisblanc BP, Guery B, Nelson S: Biological response modifiers and sepsis. In, Sepsis and Multi-organ Failure: Mechanisms and Treatment Strategies (A Fein, E Abraham, R Balk, G Bernard, R Bone, D Dantzker, and M Fink, eds). William and Wilkins, 1997.

16. Nelson S: New interventions for pneumonia. In, Sepsis (J. Rello, ed), Kluwer Academic Publishers, 1998.

17. Mason C, Nelson S: Pneumonia and septic shock. In, Critical Care Pearls. (S. Sahn and J. Heffner, eds.) Hanley and Belfus, Inc., 1997.

18. Nelson S: Cytokine-based strategies for the treatment of pneumonia. In, Respiratory Infections in the ICU. (A. Torres, M. El-Ebiary and M. Niederman, and Mensa, eds). Springer-Verlag, 1998.

19. Andresen J, Movahhed H, Nelson S: Filgrastim (r-metHuG-CSF) in pneumonia. In, Filgrastim (r-metHuG-CSF) in Clinical Practice. (G. Morstyn, M Dexter and M Foote, eds). Marcel Dekker, Inc, 1998.

20. Dale DC, Nelson S: Use of colony-stimulating factors for treatment of neutropenia and infectious diseases. In, The Neutrophil. (D. Gabrilovich, ed). Imperial College Press, 1999.

21. Andresen J, Movahhed H, Nelson S: Filgrastim (r-metHuG-CSF) in pneumonia. In, Filgrastim (r-metHuG-CSF) in Clinical Practice, 2nd Ed. (G. Morstyn, M. Dexter, and M. Foote, eds). Marcel Dekker, Inc, 1999.

22. Nelson S, Babgy GJ, Mason CM, Summer WR: Cytokines and the antibacterial defenses of the lung. In, Cytokines in Pulmonary Disease. Infection and Inflammation. (S. Nelson and T. Martin, eds). Marcel Dekker, Inc., 2000.


23. Stoltz DA, Nelson S: Immunomodulation as a therapeutic strategy for the treatment of pneumonia. In, Therapeutic Implications on Severe Community-Acquired Pneumonia. (J. Rello, ed). Edika Med, 2001.

24. Nelson S, Mason CM, Zhang P, Summer WR, Bagby GJ: Immunomodulation in sepsis. In, Critical Care Infectious Diseases (J. Rello, J. Valles, and M. Kollef , eds). Kluwer Academic Publishers, 2001.

25. Weinacker A, Nelson S: Pneumonia prevention. In, Pulmonary/Respiratory Therapy Secrets. (P. Parsons and J. Heffner, eds). Hanley and Belfus, Inc, 2001.

26. Bautista AP, Bagby GJ, Nelson S, Zhang P, Bohm RP: Functional regulation in endothelial and Kupffer cells in SIV-infected macacca mulatta following chronic alcohol administration. In, Cells of the Hepatic Sinusoids. (DL. Knook, E. Wisse, and MJP Arthur, eds). The Kupffer Cell Foundation, 2001.

27. Zhang P, Bagby GJ, Kolls J, Quinton LJ, Nelson S: Alcohol, infection and the lung. In, Infectious Diseases and Substance Abuse. (Herman Friedman et al, ed). Springer US, 2005.

28. Quinton LJ, Dale DC, Nelson S: Use of colony-stimulating factors for treatment of neutropenia and infectious diseases. In, The Neutrophils (D. Gabrilovich, ed). Imperial College Press, 2005.

29. Zhang P, Mason CM, Nelson S: Phagocytes in the pulmonary host defense system. In, Respiratory Infections (A. Torres, S. Ewig, L. Mandell, and M. Woodhead, eds). Edward Arnold Publishers, 2006.

30. Davis K, Weinacker A, and Nelson S: Pneumonia prevention. In, Pulmonary Respiratory Therapy Secrets, 3 rd Ed. (P. Parsons and J. Heffner, eds.). Mosby Elsevier, 2006.

AUDIOVISUAL:

1. Nelson S: Pneumonia: Recognition and Treatment. Family Practice Vol. 34, March 24, 1986. Audio-Digest Foundation.

2. Nelson S: Mycoplasma Infections. Family Practice Vol. 35, April 20, 1987. Audio-Digest Foundation.

3. Nelson S: Community-Acquired Pneumonia. Family Practice Vol. 37, April 17, 1989. Audio-Digest Foundation.

4. Nelson S: Pathogenesis and Prevention of Nosocomial Pneumonia. AVM Audio Visual, Inc., 1993.

5. Nelson S: Prospects for Cytokine Therapy in Nosocomial Pneumonia and Sepsis. American Thoracic Society, Convention Seminar Cassettes, 1993.

6. Nelson S: Acute Pneumonia in the Neutropenic Patient: The Potential for Colony- Stimulating Factors as Adjuvant Therapy. American Thoracic Society, Convention Seminar Cassettes, 1993.

7. Nelson S: Immunomodulation of Respiratory Infections. American Thoracic Society, Convention Seminar Cassettes, 1994.


8. Nelson S: Respiratory Infections: New Concepts in Treatment, Prevention, and Pathogenesis. American Thoracic Society, Convention Seminar Cassettes, 1994.

9. Nelson S: ACCP Fellows Conference. Medical Conventions Resources, Inc., 1995.

10. Nelson S: The Adult Patient with Cystic Fibrosis. Pulmonary Clinical Consultant, Vol. 1, American College of Chest Physicians, 1995.


12. Nelson S: Audio Forum on Chronic Bronchitis. Scientific Exchange, Inc., 1997.

13. Nelson S: Acute Exacerbations of Chronic Bronchitis: Diagnostic and Treatment Strategies. Scientific Exchange, Inc., 1997.

14. Nelson S: Innate Immunity and Pulmonary Host Defense. American Thoracic Society, Convention Seminar Cassettes, 1998.


ABSTRACTS:

l. Nelson S, Summer W, and Jakab G: Aminophylline suppresses pulmonary antibacterial defenses. Am Rev Respir Dis 127S:198, 1983.

2. Nelson S, Summer W, and Jakab G: Aminophylline-induced inhibition of pulmonary antibacterial phagocytic defenses. Program and abstracts of the ATS Eastern Section Meetings, Charlottesville, Virginia.

3. Nelson S, Laughon B, Summer W, Bartlett J, and Jakab G: A model of anaerobic pneumonia in mice. Program and abstracts of the XXIIIrd Interscience Conference on Antimicrobial Agents and Chemotherapy, Las Vegas, Nevada.

4. Nelson S, Summer W, and Jakab G: Erythromycin suppresses pulmonary antibacterial defenses -

A potential mechanism of superinfection in the lung. Am Rev Respir Dis l29S:183, l984.

5. White J, Nelson S, and Jakab G: Corticosteroids enhance impairment of pulmonary antibacterial defenses following acid aspiration. Am Rev Respir Dis l29S:l83, l984.

6. Nelson S, White J, Summer W, and Jakab G: Antibiotic efficacy against Pseudomonas aeruginosa challenge in the immuno- compromised lung. Program and abstracts of the XXIVth Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, D.C.

7. Warr G, Allegretto N, and Nelson S: Suppression of lung microbicidal activity by copper diisopropylsalicylic acid-a superoxide dismutase - like scavenger of reactive oxygen. Program and abstracts of the XXIVth Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, D.C.

8. White J, Nelson S, Jakab G, and Lanser M: Methylprednisolone impairs the bactericidal activity of alveolar macrophages. Program and abstracts of the XVIIIth Annual Meeting of the Association for Academic Surgery, San Antonio, Texas.


9. Nelson S, Laughon B, Bartlett J, Summer W, and Jakab G: Characterization of the pulmonary inflammatory response to an anaerobic bacterial challenge. Am Rev Respir Dis 131S:215, 1985.

10. Astry C, Nelson S, Tejedor R, and Summer W: Interaction of clindamycin with in vivo phagocytic defenses of the lung. Am Rev Respir Dis 133S:237, 1986

11. Tejedor R, Nelson S, Astry C, and Summer W: Acute endotoxin impairs and chronic endotoxin enhances pulmonary host defenses against Pseudomonas aeruginosa. Am Rev Respir Dis 133S:236, 1986.

12. Nelson S, Tejedor R, Astry C, and Summer W: Contrasting effects of corticosteroids on systemic and pulmonary host defenses in endotoxemia. Am Rev Respir Dis 133S:235, 1986.

13. Astry CL, Nelson S, and Summer WR: Alveolar macrophage function with acute and chronic alcohol. Am Rev Respir Dis 135S:267, 1987.

14. Harris SE, Nelson S, Astry CL, and Summer WR: Endotoxin impairs pulmonary defenses against Staphylococcus aureus. Am Rev Respir Dis 135S:267, 1987.

15. Nelson S, Astry CL, Harris SE, and Summer WR: Endotoxin-induced impairment of pulmonary antibacterial defenses. Am Rev Respir Dis 135S:77, 1987.

16. Astry CL, Nelson S, and Summer WR: Effects of acute and chronic alcohol on pulmonary host defenses. Am Rev Respir Dis 135S:34, 1987.

17. Mouton C, Nelson S, and Karam G: The bacteriology and occurrence of beta- lactamase production in anaerobic lung abscess. Program and Abstracts of the American College of Physicians, New York, New York, 1988.

18. Bainton BG, Nelson S, Chidiac C, and Summer WR: The effects of methylprednisolone and ibuprofen on pulmonary inflammation and host defense. Am Rev Respir Dis 137S:175, 1988.

19. Chidiac C, Nelson S, Bainton BG, and Summer WR: Effects of anti-inflammatory agents on pulmonary host defenses suppressed by E. coli lipopolysaccharide. Am Rev Respir Dis 137S:175, 1988.

20. Nelson S, Bagby G, and Summer W: Intratracheal lipopolysaccharide elicits tumor necrosis factor activity in bronchoalveolar lavage fluid. Am Rev Respir Dis 137S:43, 1988.

21. Nelson S, Bagby G, and Summer W: Alcohol suppresses lipopolysaccharide- induced tumor necrosis factor activity and inflammation. Am Rev Respir Dis 137S:174, 1988.

22. Bainton B, Nelson S, Chidiac C, Bagby G, and Summer WR: Methylprednisolone inhibits tumor necrosis factor and pulmonary host defenses. Program and abstracts of the XXVIIIth Interscience Conference on Antimicrobial Agents and Chemotherapy, Los Angeles, CA.

23. Nelson S, Bagby G, and Summer WR: Antibiotic-induced tumor necrosis factor during therapy for Pseudomonas aeruginosa pneumonia. Am Rev Respir Dis 139S:582, 1989.

24. Chidiac C, Nelson S, Collins MS, Bainton B, and Summer WR: Hyperimmune antipseudomonas immunoglobulin enhances host defenses in Pseduomonas aeruginosa pneumonia. Am Rev Respir Dis 139S:32, 1989.


25. Noel P, Nelson S, Bokulic R, Bagby G, Lippton H, and Summer W: Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality. Am Rev Respir Dis 139S: 222, 1989.

26. Bokulic R, Nelson S, Bagby G, Noel P, and Summer W: Inhibition of lipopolysaccharide-induced serum tumor necrosis factor by cyclosporin A. Am Rev Respir Dis 139S:355, 1989.

27. Nelson S, Noel P, Bokulic R, Bagby G, and Summer WR: Murine recombinant tumor necrosis factor enhances host defenses against Staphylococcus aureus. Am Rev Respir Dis 139S:357, 1989.

28. Nelson S, Bagby G, and Summer WR: Alcohol suppresses tumor necrosis factor and lung host defenses. Alcohol Clin Exp Res 13:330, 1989.

29. Mason CM, Dunn CW, Nelson S, Summer WR, and Dalnogare AR: Upper gastrointestinal gram-negative bacillary colonization occurs concurrently with oropharyngeal colonization in a rat model. Am Rev Respir Dis 141S:334, 1990.

30. deBoisblanc BP, Jawda A, Svec F, Nelson S, and Summer WR: Effect of anabolic steroids on diaphragmatic tension generation in a rat model of cystic fibrosis. Am Rev Respir Dis 141S:549, 1990.

31. Nelson S, Mason C, Bagby G, Nakamura C, and Summer WR: Lipopolysaccharide-induced inhibition of intrapulmonary tumor necrosis factor and lung antibacterial defenses. Am Rev Respir Dis 141S:512, 1990.

32. Nelson S, Bagby G, Nakamura C, and Summer WR: Ethanol-induced suppression of tumor necrosis factor and pulmonary antibacterial defenses. Am Rev Respir Dis 141S:530, 1990.

33. Nakamura C, Nelson S, Lippton H, Bagby G, and Summer WR: Contrasting effects of misoprostol on systemic and intra-pulmonary lipopolysaccharide-induced tumor necrosis factor. Am Rev Respir Dis 141S:131, 1990.

34. Nelson S, Mason C, Bagby G, Andresen J, and Summer WR: Effect of murine recombinant granulocyte-macrophage colony-stimulating factor on lipopolysaccharide-induced tumor necrosis factor. Am Rev Respir Dis 141S:677, 1990.

35. Nelson S, Bagby G, Andresen J, Nakamura C, and Summer WR: Granulocyte colony-stimulating factor enhances pulmonary host defenses suppressed by alcohol. Am Rev Respir Dis 141S:530, 1990.

36. Nelson S, Bagby G, Plessala K, Thompson J, Wilson L, and Summer WR: Efficacy of anti-tumor necrosis factor-alpha antibody in intravascular and peritonitis models of bacterial infections. Am Rev Respir Dis 141S:921, 1990.

37. Dowty BJ, Rodriguez de Turco E, Nelson S, Hagar A, and Spitzer JA: Effect of systemic endotoxin on superoxide anion release and signal transduction in rat alveolar macrophages. FASEB J 5:A1629, 1991.


38. Spolarics Z, Schuler A, Lang CH, Bagby GJ, Nelson S, and Spitzer JJ: Acute upregulation of glucose metabolism after granulocyte-macrophage colony-stimulating factor (GM-CSF) administration. FASEB J 5:A545, 1991.

39. Shellito JE, Sniezek MJ, Warnock M, and Nelson S: Chronic alcohol ingestion enhances host susceptibility to Pneumocystis carinii infection in mice. Am Rev Respir Dis 143S:207, 1991.

40. Havill AM, Andresen JW, Korach E, and Nelson S: Enhancement of endotoxin-induced lethality in the mouse by GM-CSF. Am Rev Respir Dis 143S:236, 1991.

41. Nelson S, Bagby G, and Summer W: Anti-tumor necrosis factor-alpha antibody suppresses pulmonary antibacterial defenses. Am Rev Respir Dis 143S:393, 1991.

42. Nelson S, Bagby G, Andresen J, Shellito J, and Summer W: Intratracheal granulocyte colony-stimulating factor enhances systemic and pulmonary host defenses. Am Rev Respir Dis 143S:398, 1991.

43. Mason CM, Bagby GJ, Summer WR, and Nelson S: Antibody to tumor necrosis factor attenuates lipopolysaccharide-induced gram-negative bacillary oropharyngeal colonization. Am Rev Respir Dis 143S:710, 1991.

44. King JC, Mason CM, Onofrio J, Summer WR, and Nelson S: Granulocyte colony-stimulating factor enhances pulmonary capillary leak following in vivo alpha-naphthylthiourea (ANTU) lung injury. Chest 100:7S, 1991.

45. Nelson S, Nakamura C, Andresen J, Cecchini M, Bagby G, and Summer W: Anti-granulocyte colony-stimulating factor antibody suppresses pulmonary antibacterial defenses. Am Rev Respir Dis 145S:13, 1992.

46. Greenberg S, Xie J, Wang Y, Nelson S, and Summer W: Characteristics of tumor necrosis factor-alpha suppression of nitric oxide release from pulmonary vascular endothelium. Am Rev Respir Dis 145S:209, 1992.

47. Shellito J, Beck J, Kolls J, and Nelson S: Alveolar macrophage release of tumor necrosis factor during murine Pneumocystis carinii pneumonia. Am Rev Respir Dis 154S:247, 1992.

48. Mason C, Dobard E, Summer W, and Nelson S: Granulocyte colony-stimulating factor attenuates bacterial translocation in rats. Am Rev Respir Dis 145S:336, 1992.

49. Nelson S, Nakamura C, Shellito J, Bagby G, and Summer W: Intratracheal gamma-interferon enhances pulmonary host defenses against Pseudomonas aeruginosa. Am Rev Respir Dis 145S:337, 1992.

50. Shellito J, Nelson S, and Sorensen RU: Pyocyanine, a product of Pseudomonas aeruginosa, inhibits the release of reactive nitrogen intermediates from murine alveolar macrophages. Am Rev Respir Dis 145S:551, 1992.

51. Kolls J, Larson J, Deininger P, Shellito J, Nelson S, Beckerman R, and Summer W: Constitutive expression of mRNA for tumor necrosis factor-alpha in murine alveolar macrophages. Am Rev Respir Dis 145S:833, 1992.


52. Bagby G, Nelson S, and Summer W: Endogenous tumor necrosis factor is a positive modulator of pulmonary host defenses against Pseudomonas aeruginosa. Program and abstracts of the 4th International TNF Congress, Veldhoven, The Netherlands, 1992.

53. Malinski T, Wang Y, Xie J, Kolls J, Nelson S, Shellito J, and Summer WR ,Greenberg S: Acute administration of ethanol releases nitric oxide from endothelium and adrenal glands but inhibits its release from macrophages. FASEB J 7:A824, 1993.

54. Xie J, Wang Y, Kolls S, Nelson S, and Summer WR, and Greenberg S: Ethanol induced relaxation is mediated by release of nitric oxide and prostaglandins in pulmonary artery and vein. FASEB J 7:A843, 1993.

55. Greenberg S, LeBlanc R, Werner A, Xie J, Wang Y, Weinberg A, Kolls J, Shellito J, Nelson S, and Summer W: Endotoxin-induced hypotension is mediated by nitric oxide from macrophages: effect of prednisolone, aminotriazine and colony-stimulating factors. Am Rev Respir Dis 147S:99, 1993.

56. Nelson S, Dowty B, Mason C, Bagby G, and Summer W: Gamma-interferon attenuates ethanol-induced suppression of lipopolysaccharide-stimulated tumor necrosis factor activity in lung and serum. Am J Respir Dis 147S:203, 1993.

57. Shellito J, D'Souza N, Nelson S, Greenberg S, and Summer W: Nitric oxide and interferon-induced enhancement of pulmonary host defenses against Pseudomonas aeruginosa. Am J Respir Dis 147S:A203, 1993.

58. Mason CM, Dobard E, Nelson S, and Summer W: Intraportal lipopolysaccharide is associated with impairment of pulmonary host defense in rats. Am J Respir Dis 147S:203, 1993.

59. deBoisblanc B, Summer WR, Mason C, Shellito J, Logan E, Bear M, Johnson S, and Nelson S: Phase 1 trial of granulocyte-colony stimulating factor in severe community acquired pneumonia. Am J Respir Dis 147S:204, 1993.

60. Tutor JD, Mason C, Dobard E, Beckerman R, Summer WR, and Nelson S: Lung injury is associated with loss of compartmentalization of alveolar tumor necrosis factor in the isolated perfused rat lung. Am J Respir Dis 147S:730, 1993.

61. Greenberg SS, Xie J, Kolls J, Summer WR, and Nelson S: Ethanol selectively suppresses gene expression for inducible nitric oxide synthase II in lung phagocytes and decreases lung clearance of K. pneumoniae. Am J Respir Crit Med 149S:A120, 1994.

62. Mason C, Adams L, Nelson S, Summer W, and Shellito J: Mycobacterial cell wall antigens elicit pulmonary host defense mechanisms. Am J Respir Crit Care Med 149S:A613, 1994.

63. Nelson S, Mason C, Bagby G, and Summer WR: The contrasting effects of anti-tumor necrosis factor antibody versus granulocyte colony-stimulating factor on pulmonary host defenses against Candida albicans. Am J Respir Crit Care Med 149S:A872, 1994.

64. Nelson S, Mason C, Shellito J, Bagby G, and Summer WR: The effects of gamma-interferon on lipoarabinomannan-induced tumor necrosis factor in the lung. Am J Respir Crit Care Med 149S:A870, 1994.


65. Xie J, Kolls J, Bagby G, Nelson S, Summer WR, Lyons R, and Greenberg SS: Endotoxin induced stimulation of alveolar macrophage and neutrophil gene expression for nitric oxide is independent of tumor necrosis factor. Am J Respir Crit Care Med 149S:A870, 1994.

66. Skerrett SJ, Bagby GJ, and Nelson S: Antibody to tumor necrosis factor impairs pulmonary clearance of Legionella pneumophila. Am J Respir Crit Care Med 149S:A871, 1994.

67. Mandujano JF, D'Souza NB, Nelson S, Beckerman RC, Summer WR, and Shellito J: Reduction in intensity of Pneumocystis carinii pneumonia in mice by subcutaneous administration of granulocyte-macrophage colony-stimulating factor. Am J Respir Crit Care Med 149S:A289, 1994.

68. D'Souza NB, Mandujano JF, Nelson S, Summer WR, and Shellito JE: Chronic alcohol ingestion predisposes otherwise healthy mice to infection with Pneumocystis carinii. Alcohol Clin Exp Res 18:439, 1994.

69. D'Souza NB, Nelson S, Summer WR, and Deaciuc IV: Alcohol-induced inhibition of alveolar macrophage reactive nitrogen intermediates (RNI) release. Alcohol Clin Exp Res 18: 439, 1994.

70. D'Souza NB, Nelson S, Summer WR, and Deaciuc IV: Modulation by alcohol (ETOH) of alveolar macrophage (AM) interleukin (IL)-6 cell-surface receptors in the rat. Alcohol Clin Exp Res 18: 439, 1994.

71. Kolls JK, Xie J, Lei D, Greenberg S, and Nelson S: Acute exposure to ethanol blocks tumor necrosis factor production in vivo by a post transcriptional mechanism. Alcohol Clin Exp Res 18:441, 1994.

72. Deaciuc IV, Nelson S, and D'Souza NB: The effect of acute and chronic alcohol (ETOH) administration to rats on tumor necrosis factor (TNF)-α cell-surface receptors of alveolar macrophages. Alcohol Clin Exp Res 18:47A, 1994.

73. Kolls JK, Lei D, Nelson S, Summer W, and Shellito J: Exacerbation of murine P. carinii infection by adenoviral-mediated gene transfer of a TNF soluble receptor. Am J Respir Crit Care Med 151S:A13, 1995.

74. Nelson S, Bagby S, Mason C, and Summer W: Ethanol suppresses Escherichia coli-induced plasma granulocyte colony-stimulating factor. Am J Respir Crit Care Med 151S:A14, 1995.

75. Kolls J, Lei D, Xie J, Greenberg S, and Nelson S: Divergent effect of in vivo ethanol on pulmonary TNF and inducible nitric oxide synthase gene expression. Am J Respir Crit Care Med 151S:A122, 1995.

76. Rome C, Bagby G, Summer W, and Nelson S: Therapeutic efficacy of granulocyte colony-stimulating factor in the treatment of Group B streptococcal sepsis in neonatal rats. Am J Respir Crit Care Med 151S:A242, 1995.

77. deBoisblanc B, Harris K, Bagby G, Svec F, and Nelson S: Effect of DHEA administration on serum activity of TNF after intravenous LPS. Am J Respir Crit Care Med 151S:A242, 1995.

78. Mason CM, Guery B, Dobard E, Summer W, and Nelson S: Keratinocyte growth factor protects against lung injury induced by alpha-naphthylthiourea. Am J Respir Crit Care Med 151S:A345, 1995.


79. Daifuku R, Movahhed H, Fotheringham N, Bear MB, and Nelson S: Time to resolution of morbidity (TRM): an endpoint for assessing the clinical cure of community acquired pneumonia. Am J Respir Crit Care Med 151S:A473, 1995.

80. Wunderink RG, Leeper KV, Schein RMH, Nelson S, deBoisblanc B, Baker F, Fotheringham N, and Logan E: Clinical response to filgrastim (r-metHuG-CSF) in pneumonia with severe sepsis. Am J Respir Crit Care Med 153S:A123, 1996.

81. Mason CM, Guery B, Dobard E, Summer W, and Nelson S: Intraportal lipopolysaccharide impairs alveolar macrophage antibacterial defenses. Am J Respir Crit Care Med 153S:A258, 1996.

82. Stoltz DA, Bagby GJ, Mason CM, and Nelson S: Intratracheal keratinocyte growth factor preserves pulmonary antibacterial defenses in alpha-naphthylthiourea-induced lung injury. Am J Respir Crit Care Med 153S:A258, 1996.

83. Guery B, deBoisblanc BP, Nelson S, Dobard E, Beaucaire G, Summer W, and Mason C: Keratinocyte growth factor protects against mechanical ventilation lung injury. Am J Respir Crit Care Med 153S:A393, 1996.

84. Guery B, Mason C, Dobard E, Beaucaire G, Summer W, and Nelson S: Keratinocyte growth factor attenuates the consequences of alpha-naphthylthiourea-induced lung injury by increasing transalveolar sodium reabsorption. Am J Respir Crit Care Med 153S:A433, 1996.

85. McKenna PH, Nelson S, and Andresen J: Filgrastim (rhuG-CSF) enhances ciprofloxacin uptake and bactericidal activity of human neutrophils in vitro. Am J Respir Crit Care Med 153S:A535, 1996.

86. Nelson S, Farkas S, Fotheringham N, Ho H, Marrie T, and Movahhed H: Filgrastim in the treatment of hospitalized patients with community acquired pneumonia (CAP). Am J Respir Crit Care Med 153S:A535, 1996.

87. Kolls JK, Lei D, Shellito J, Nelson S, and Summer W: Organ-specific cytokine gene therapy: Compartmentalized activation of the alveolar macrophage by adenoviral-mediated gene transfer of the murine interferon-gamma gene. Am J Respir Crit Care Med 153S:A764, 1996.

88. Nelson S, Fotheringham N, and Movahhed H: Filgrastim reduces adult respiratory distress syndrome and other serious complications in patients with multilobar pneumonia. Eur Respir J 9S:55, 1996.

89. Zhang P, Summer WR, Bagby GJ, Stoltz DA, and Nelson S: Ethanol inhibits neutrophil β2-integrin expression and phagocytosis during endotoxemia. Am J Respir Crit Care Med 155S:A292, 1997.

90. Kolls JK, Lei D, Nelson S, Odom G, Summer WR, and Shellito JE: Adenoviral-mediated gene transfer of the murine interferon-gamma gene prevents acquisition of P. carinii pneumonia in CD4-depleted mice. Am J Respir Crit Care Med 155S:A458, 1997.


91. Nelson S, Marrie T, and Movahhed H: Filgrastim (granulocyte colony-stimulating factor[G-CSF]) reduces morbidity in patients with a history of chronic alcohol abuse hospitalized with community-acquired pneumonia. Am J Respir Crit Care Med 155S:A801, 1997.

92. Zhang P, Bagby GJ, Stoltz DA, Spitzer JA, Summer WR, and Nelson S: Modulation of the inflammatory response by granulocyte colony-stimulating factor in rats challenged with intrapulmonary endotoxin. Am J Respir Crit Care Med 155S:A801, 1997.

93. Lei D, Shellito S, Nelson S, Summer WR, and Kolls JK: Organ-specific cytokine gene therapy: attenuation of ethanol induced TNF suppression by adenoviral-mediated gene transfer of the murine interferon-gamma gene. Am J Respir Crit Care Med 155S:A802, 1997.

94. Mason CM, Dobard E, Summer W, Kolls JK, and Nelson S: Effect of alcohol on murine lung interleukin (IL)-12. Am J Respir Crit Care Med 155S:A803, 1997.

95. Stoltz DA, Bagby GJ, Bohm Jr. RP, Zhang P, and Nelson S: Lipopolysaccharide-induced tumor necrosis factor-α by Rhesus monkey alveolar macrophages is suppressed by ethanol. Am J Respir Crit Care Med 155S:A803, 1997.

96. Mason CM, Dobard E, Summer W, Kolls J, and Nelson S: Ethanol and lung interleukin (IL)-12. Alcohol Clin Exp Res 21:45A, 1997.

97. Zhang P, Prakash O, Shellito JE, Stoltz DA, and Nelson S: Acute ethanol administration suppresses endotoxin-induced β-integrin expression on PMNS in normal and HIV-1-TAT transgenic mice. Alcohol Clin Exp Res 21:46A, 1997.

98. Zhang P, Summer WR, Bagby GJ, Stoltz DA, and Nelson S: Acute ethanol intoxication inhibits neutrophil β-integrin expression in endotoxin treated rats. Alcohol Clin Exp Res 21:46A, 1997.

99. Nelson S, Stoltz DA, and Bagby G: Ethanol suppresses Escherichia coli-induced plasma granulocyte colony-stimulating factor. Alcohol Clin Exp Res 21:46A, 1997.

100. Zhang P, Nelson S, Summer WR, and Spitzer JA: Acute ethanol intoxication suppresses the pulmonary inflammatory response in rats. Alcohol Clin Exp Res 21:47A, 1997.

101. Lei D, Zhang P, Stoltz D, Ye P, Nelson S, Bagby G, Summer WR, Shellito J, and Kolls J: Augmentation of pulmonary host defense in alcoholic rats by IFN gene therapy: overexpression of adhesion molecule CD11b/c. Alcohol Clin Exp Res 21:82A, 1997.

102. Lei D, Stoltz DA, Shellito J, Nelson S, Summer WR and Kolls J: Pulmonary cytokine gene therapy: attenuation of ethanol induced TNF suppression by adenoviral-mediated gene transfer of the murine interferon-gamma gene. Alcohol Clin Exp Res 21:82A, 1997.

103. Mason CM, Dobard E, Summer W, and Nelson S: Effects of ethanol on bacterial and endotoxin translocation from the gut. Alcohol Clin Exp Res 21:82A, 1997.


104. Stoltz DA, Bagby GJ, Bohm RP Jr.,Zhang P, and Nelson S: Ethanol suppression of lipopolysaccharide-induced tumor necrosis factor production by alveolar macrophages from uninfected and SIV-infected asymptomatic rhesus monkeys. Alcohol Clin Exp Res 21:82A, 1997.

105. Zhang P, Bagby GJ, Stoltz DA, Summer WR, and Nelson S: Enhancement of peritoneal leukocyte function by granulocyte colony-stimulating factor in rats with abdominal sepsis. Am J Respir Crit Care Med 157:A27, 1998.

106. Mason C, Dobard E, deBoisblanc B, Guery B, Nelson S, and Summer W: Keratinocyte growth factor, hydrostatic pulmonary edema, and lymph flow. Am J Respir Crit Care Med 157:A202, 1998.

107. Zhang P, Spitzer JA, Summer WR, and Nelson S: Inhibition of serine/threonine protein phosphatase enhances phagocytic activity of alveolar macrophages in rats challenged with or without intratracheal endotoxin. Am J Respir Crit Care Med 157:A241, 1998.

108. Zhang P, Prakash O, Shellito JE, Xie M, Stoltz DA, Bagby GJ, and Nelson S: Ethanol intoxication suppresses endotoxin-induced β2-integrin expression on neutrophils in normal and HIV-1-TAT transgenic mice. Am J Respir Crit Care Med 157:A864, 1998.

109. Stoltz DA, Bagby GJ, Bohm RP Jr., Murphey-Corb M, Wilson LA, Zhang P, and Nelson S: Ethanol enhances simian immunodeficiency virus (SIV) replication in rhesus monkey peripheral blood mononuclear cells in vitro. Am J Respir Crit Care Med 157:A865, 1998.

110. Zhang P, Bagby GJ, Summer WR and Nelson S: G-CSF does not prevent alcohol-induced inhibition of the TNF-α and MIP-2 production in the lung in response to intratracheal endotoxin. Alcohol Clin Exp Res 23:25A, 1999.

111. Zhang P, Bagby GJ, Summer WR, and Nelson S: Granulocyte colony-stimulating factor enhances pulmonary host defense function in ethanol-intoxicated rats. Alcohol Clin Exp Res 23:1999.

112. Mason C, Dobard E, Kolls J, and Nelson S: Effect of ethanol on murine interlelukin (IL)-12 p40 and p70 production. Alcohol Clin Exp Res 23:27A, 1999.

113. Zhang Z, Cork J, Nelson S, and Kolls JK: Accumulated TNF-α is co-localized with the golgi apparatus in ethanol-treated Mono Mac 6 cells. Alcohol Clin Exp Res 23:27A, 1999.

114. Zhang Z, Stoltz DA, Nelson S, Bagby GJ, Good D, and Kolls JK: Ethanol inhibits TNF-α receptor II shedding in peripheral blood monocytes from rhesus macagues infected with SIV. Alcohol Clin Exp Res 23:27A, 1999.

115. Ye P, Garvey PB, Huang W, Good DE, Zhang Z, Schwarzenberger P, Summer WR, Shellito JE, Nelson S and Kolls JK: IL-17 increases lung immunity and improves lung host defense against K. pneumoniae infection. Am J Respir Crit Care Med 159: A239, 1999.


116. Welsh DA, Summer, WR, Dobard E, Nelson S, and Mason CM: Effect of keratinocyte growth factor in ventilator induced lung injury. Am J Respir Crit Care Med 159: A479, 1999.

117. Mason CM, Dobard E, Kolls J, and Nelson S: Ethanol and murine interleukin (IL)-12 production: role of p40 regulation. Am J Respir Crit Care Med 159:A660, 1999.

118. Nelson S, Stoltz DA, Zhang P, and Bagby GJ: The host response to intravenous E. coli is inhibited by anti-granulocyte colony-stimulating factor (G-CSF) antibody. Am J Respir Crit Care Med 159:A750, 1999.

119. Zhang P, Bagby GJ, Stoltz DA, Summer WR, and Nelson S: Granulocyte colony-stimulating factor modulates the pulmonary host response to endotoxin in the absence and presence of ethanol intoxication. Am J Respir Crit Care Med, 159:A753, 1999.

120. Zhang P, Bagby GJ, Summer WR, and Nelson S: Modulation of the pulmonary cytokine response to endotoxin by granulocyte colony-stimulating factor. Am J Respir Crit Care Med 159:A927, 1999.

121. Zhang P, Nelson S, Summer WR, and Bagby GJ: Effects of chronic alcohol intoxication on in vitro T lymphocyte Ki67-Ag expression in SIV-infected rhesus macaques. Alcohol Clin Exp Res 24:19A, 2000.

122. Kolls JK, Zheng M, Schwarzenberger P, Zhang Z, Ye P, Nelson S, and Shellito JE: Suppression on IL-17 and pulmonary host defenses by acute ethanol. Alcohol Clin Exp Res 24:19A, 2000.

123. Zhang P, Bagby GJ, Summer WR, and Nelson S: Alcohol suppresses C-X-C chemokine production by alveolar macrophages stimulated in vitro with endotoxin. Alcohol Clin Exp Res 24:19A, 2000.

124. Zhang P, Bagby GJ, Summer WR, and Nelson S: Granulocyte colony-stimulating factor enhances neutrophil chemotaxis and attenuates alcohol-induced suppression of neutrophil chemotaxis in vitro. Alcohol Clin Exp Res 24:20A, 2000.

125. Zhang Z, Lancaster J, Oliver P, Nelson S and Kolls JK: Activation of TACE-mediated ectodomain shedding in human monocytes by chronic ethanol. Alcohol Clin Exp Res 24:20A, 2000.

126. Kolls JK, Lancaster J, Oliver P, Nelson S, and Zhang Z: Suppression of TACE-mediated ectodomain shedding by acute ethanol. Alcohol Clin Exp Res 24:21A, 2000.

127. Boe D, Zhang P, Nelson S, and Bagby G: Ethanol intoxication suppresses lung chemokine production following infection with Streptococcus pneumoniae. Alcohol Clin Exp Res 24:21A, 2000.


128. Root R, Nelson S, Dale D, Martin T, and Welch W: A multicenter, double blind, placebo-controlled study of filgrastim (R-METHUGCSF) in the treatment of patients with multilobar community-acquired pneumonia. Am J Respir Crit Care Med 161:A91, 2000.

129. Root R, Nelson S, Dale D, Martin T, and Welch W: Filgastrim (R-METHUGCSF) as adjunctive therapy in the treatment of patients with pneumonia and severe sepsis: results of a placebo-controlled trial. Am J Respir Crit Care Med 161:A91, 2000.

130. Boe DM, Zhang P, Nelson S, and Bagby GJ: Ethanol intoxication suppresses lung antibacterial defenses against Streptococcus pneumoniae. Am J Respir Crit Care Med 161:A124, 2000.

131. Kolls JK, Ye P, Nelson S, Summer WR, and Shellito JE: Establishment of a critical role for CD4+ T-cells in a murine model of Streptococcus pneumoniae infection. Am J Respir Crit Care Med 161:A216, 2000.

132. Nelson S, Zhang P, Summer WR, and Bagby G: Granulocyte colony-stimulating factor is not compartmentalized following an intrapulmonary bacterial challenge. Am J Respir Crit Care Med 161:A216, 2000.

133. Welsh DA, Summer WR, Nelson S, Mason CM, and Lallier T: KGF effects expression of alveolar epithelial cell integrins and extracellular matrix (ECM) components. Am J Respir Crit Care Med 161:A444, 2000.

134. Zhang, P, Holmes M, Bagby GJ, Summer WR, and Nelson S: Compartmentalization of macrophage inflammatory protein-2, but not cytokine-induced neutrophil chemoattractant, in rats challenged with intratracheal endotoxin. Am J Respir Crit Care Med 161:A465, 2000.

135. Kolls JK, Zhang Z, Ye P, Shellito JE, and Nelson S: Alcohol suppresses TACE-ectodomain shedding from monocytes: implications for pulmonary host defenses. Am J Respir Crit Care Med 161:A588, 2000.

136. Zhang P, Bagby GJ, Summer WR, and Nelson S: Alcohol suppresses endotoxin-induced macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant production by alveolar macrophages. Am J Respir Crit Care Med 161:A590, 2000.

137. Mason CM, Dobard E, and Nelson S: Effect of ethanol on infection with Mycobacterium tuberculosis in mice. Am J Respir Crit Care Med 161:A647, 2000.

138. Zhang P, Bagby GJ, Summer WR, and Nelson S: Granulocyte colony-stimulating factor and neutrophils modulate the pulmonary chemokine response. Am J Respir Crit Care Med 161:A846, 2000.

139. Mason C, Dobard E, and Nelson S: Effect of ethanol on BCG-induced protection against murine pulmonary tuberculosis. Alcohol Clin Exp Res 25:27A, 2001.


140. Prakash O, Rodriguez VE, Tang ZY, Zhou P, Coleman R, Dhillon G, Shellito J, and Nelson S: Ethanol potentiates HIV-1 Tat-induced bone marrow toxicity in transgenic mice. Alcohol Clin Exp Res 25:27A, 2001.

141. Bagby GJ, Brown JA, Kolls JK, Schexnayder JA, Rockar RA, and Nelson S: Chronic binge alcohol consumption increases early viral load in SIV-infected rhesus macaques. Alcohol Clin Exp Res 25:27A, 2001.

142. Zhang P, Bagby GJ, Summer WR, and Nelson S: In vitro effects of alcohol on the binding of C-X-C chemokines to polymorphonuclear leukocytes. Alcohol Clin Exp Res 25:29A, 2001.

143. Zhang P, Bagby GJ, Summer WR, and Nelson S: Acute ethanol intoxication suppresses the systemic chemokine response in rats with endotoxemia. Alcohol Clin Exp Res 25:30A, 2001.

144. Boé DM, Zhang P, Nelson S, and Bagby GJ: Alcohol-induced suppression of lung chemokine production following infection with Streptococcus pneumoniae. Alcohol Clin Exp Res 25:30A, 2001.

145. Prakash O, Tang ZY, Peng X, Zhou P, Kolls J, Shellito J, and Nelson S: Alcohol inhibits thymidine kinase activity essential for activation of AZT (Zidovudine) to its anti-HIV form. Alcohol Clin Exp Res 25:30A, 2001.

146. Welsh DA, Zhang P, Mason CM, Bagby GJ, Summer WR, and Nelson S: Effect of alveolar epithelial cells on LPS-induced TNF-α production by circulating PMN. Am J Respir Crit Care Med 163:A274, 2001.

147. Boé D, Zhang P, Nelson S, and Bagby GJ: Ethanol-induced suppression of lung chemokine production in a neutropenic model of pneumococcal pneumonia. Am J Respir Crit Care Med 163:A383, 2001.

148. Ye P, Hilton C, Zheng M, Schwarzenberger P, Nelson S, Summer WR, Shellito J, and Kolls JK: Differences in IL-17 response against gram (-) and gram (+) bacterial lung infections. Am J Respir Crit Care Med 163:A274, 2001.

149. Welsh DA, Zhang P, Mason CM, Bagby GJ, Summer WR, and Nelson S: Circulating PMN modulate LPS-induced CINC production by alveolar epithelial cells. Am J Respir Crit Care Med 163:A593, 2001.

150. Mason CM, Dobard E, Shellito J, and Nelson S: CD4 lymphocyte responses to murine pulmonary TB. Am J Respir Crit Care Med 163:A662, 2001.

151. Zhang P, Bagby GJ, Summer WR, and Nelson S: Contrasting chemokine responses in the lung and systemic circulation following lipopolysaccharide challenge. Am J Respir Crit Care Med 163:A944, 2001.

152. Holmes M, Zhang P, Nelson S, Summer WR, and Bagby GJ: Neutrophils alter the pulmonary cytokine response to intratracheal LPS. Am J Respir Crit Care Med 163:A948, 2001.


153. Zhang P, Bagby GJ, Summer WR, and Nelson S: Polymorphonuclear leukocytes modulate the systemic macrophage inflammatory protein-2 response in rats with endotoxemia. Am J Respir Crit Care Med 163:A986, 2001.

154. Zhang P, Bagby GJ, Purcell JE, Summer WR, and Nelson S: Neutrophil function in SIV-infected rhesus macaques with or without chronic binge alcohol consumption. Alcohol Clin Exp Res 26:47A, 2002.

155. Bagby GJ, Purcell JE, Zhang P, and Nelson S: Ethanol suppresses the LPS-induced TNFα response of blood mononuclear cells obtained from SIV (-) and SIV (+) rhesus macaques. Alcohol Clin Exp Res 26:48A, 2002.

156. Zhang P, Quinton LJ, Bagby GJ, Summer WR, and Nelson S: Acute alcohol intoxication inhibits interferon-ү-induced enhancement of MIP-2 response in the lung to intrapulmonary endotoxin challenge. Alcohol Clin Exp Res 26:50A, 2002.

157. Zhang P, Bagby GJ, Summer WR, and Nelson S: Alcohol suppresses β2-integrin expression on PMNs but not the binding of CXC chemokines to these immune effector cells. Alcohol Clin Exp Res 26:50A, 2002.

158. Kantrow SP, Marino RM, Jaligam VR, Jenkins MY, and Nelson S: Ethanol potentiates lymphocyte death signaling. Alcohol Clin Exp Res 26:51A, 2002.

159. Prakash O, Tang Z-Y, Peng X, Zhou P, Coleman R, and Nelson S: Ethanol inhibits human Kaposi’s sarcoma (KS) cell-derived tumorigenesis in nude mice. Alcohol Clin Exp Res 26:58A, 2002.

160. Winsauer PJ, Moerschbaecher JM, Gerak LR, Brauner IN Purcell JE, Bagby GJ, and Nelson S: Alcohol unmasks SIV-induced cognitive impairments in rhesus monkeys. Alcohol Clin Exp Res 26:154A, 2002.

161. Zhang P, Bagby GJ, Quinton LJ, Summer WR, and Nelson S: Interferon-ү enchances the pulmonary cytokine-induced neutrophil chemoattractant response to intratracheal lipopolysaccharide. Am J Respir Crit Care Med 165:A90, 2002.

162. Quinton LJ, Nelson S, Zhang P, Boé DM, and Bagby GJ: The granulocyte colony-stimulating factor response following intrapulmonary and systemic bacterial challenges. Am J Respir Crit Care Med 165:A90, 2002.

163. Mason CM, Dobard E, Shellito J, and Nelson S: Effect of alcohol on CD4+ lymphocytes in murine pulmonary TB. Am J Respir Crit Care Med 165: A196, 2002.

164. Zhang P, Bagby GJ, Summer WR, and Nelson S: Endotoxemia suppresses pulmonary neutrophil recruitment in the presence of high pulmonary chemokine levels following intratracheal lipopolysaccharide. Am J Respir Crit Care Med 165:A816, 2002.


165. Zhang P, Bagby GJ, Summer WR, and Nelson S: Alcohol suppresses neutrophil adhesion molecule expression without affecting CXC chemokine binding to these cells. Am J Respir Crit Care Med 165:A816, 2002.

166. Zhang P, Bagby GJ, Purcell J, Veazey RS, and Nelson S: Chronic alcohol consumption accelerates the loss of effector and central memory CD4 T-cells in SIV-infected rhesus macaques. Alcohol Clin Exp Res 27:35A, 2003.

167. Bagby GJ, Purcell J, Zhang P, Kolls J, and Nelson S: Chronic-binge alcohol consumption increases viral set-point in simian immunodeficiency virus (SIV) infected macaques. Alcohol Clin Exp Res 27:35A, 2003.

168. Prakash O, Peng Z, Wang G, Bagby GJ, and Nelson S: Ethanol decreases thymidine kinase (TK) activity and phosphorylation of zidovudine (ZDV) to its anti-retrovirally active ZDV-triphosphate form. Alcohol Clin Exp Res 27:35A, 2003.

169. Shahbazian LM, Zhang P, Quinton L, Bagby G, and Nelson S: Interferon-gamma attenuates acute alcohol-induced suppression of bacterial clearance in mice challenged with Escherichia coli. Alcohol Clin Exp Res 27:36A, 2003.

170. Mason C, Dobard E, Zhang P, and Nelson S: Effect of ethanol on murine pulmonary tuberculosis. Alcohol Clin Exp Res 27:36A, 2003.

171. Quinton L, Zhang P, Nelson S, Summer W, and Bagby G: Acute ethanol intoxication inhibits interferon-ү-induced enhancement of pulmonary chemokine production in response to intratracheal endotoxin. Alcohol Clin Exp Res 27:36A, 2003.

172. Shahbazian LM, Zhang P, Bagby G, and Nelson S: Acute alcohol intoxication inhibits granulopoiesis induced by exogenous G-CSF in mice. Alcohol Clin Exp Res 27:37A, 2003.

173. Happel KI, Quinton LJ, Zhang P, Bagby GJ, and Nelson S: Acute ethanol intoxication inhibits the ELR+ and ELR-CXC chemokine response to intratracheal endotoxin. Alcohol Clin Exp Res 27:89A, 2003.

174. Shahbazian LM, Zhang P, Quinton LJ, Bagby GJ and Nelson S: Interferon-gamma enhances bacterial clearance in mice challenged with intravenous Escherichia coli in the absence and presence of acute ethanol intoxication. Am J Respir Crit Care Med 167:A199, 2003.

175. Shahbazian LM, Zhang P, Bagby GJ, and Nelson S: Inhibition of the G-CSF-induced granulopoietic response in mice with acute alcohol intoxication. Am J Respir Crit Care Med 167:A264, 2003.

176. Zhang P, Saluja JS, Shahbazian LM, Bagby GJ, Summer WR, and Nelson S: Endotoxemia suppresses neutrophil chemotactic activity. Am J Respir Crit Care Med 167:A308, 2003.

177. Quinton LJ, Nelson S, Zhang P, and Bagby GJ: Translocation of cytokine-induced neutrophil chemoattractant, but not macrophage inflammatory


protein-2 from the pulmonary compartment into the blood. Am J Respir Crit Care Med 167:A642, 2003.

178. Zhang P, Quinton LJ, Bagby GJ, Summer WR, and Nelson S: Inhibition of interferon- induced enchancement of the pulmonary CINC response to intratracheal-ץendotoxin by acute alcohol intoxication. Am J Respir Crit Care Med 167:A643, 2003.

179. Happel KI, Zheng M, Bagby GJ, Nelson S, Shellito JE, and Kolls, JK: Toll-like receptor 4 is required for pulmonary expression of interleukin 17 in response to Klebsiella pneumoniae infection. Am J Respir Crit Care Med 167:A701, 2003.

180. Happel KI, Zheng M, Bagby GJ, Nelson S, Shellito JE, and Kolls JK: T cell production of interleukin 17 in response to Klebsiella pneumoniae does not require cell contact. Am J Respir Crit Care Med 167:A759, 2003.

181. Nelson S, Zhang P, Purcell J, Rasmussen T, MacLean A, and Bagby G: The effect of pneumococcal pneumonia on SIV replication in the pulmonary and systemic compartments. Am J Respir Crit Care Med 169:A232, 2004.

182. Gamble L, Zhang P, Quinton LJ, Bagby GJ, and Nelson S: Alterations in systemic and bone marrow granulopoietic cytokine levels during endotoxemia. Am J Respir Crit Care Med 169: A304, 2004.

183. Zhang P, Shahbazian LM, Quinton LJ, Bagby GJ, Summer WR, and Nelson S: Enhancement of granulopoiesis and mobilization of myeloid progenitor cells to the systemic circulation following an intrapulmonary challenge with Escherichia coli. Am J Respir Crit Care Med 169: A559, 2004.

184. Happel KI, Quinton LJ, Zhang P, Shellito JE, Bagby GJ, and Nelson S: Klebsiella pneumoniae induced expression of IL-23 and IL-27 from alveolar macrophages is inhibited by acute ethanol. Am J Respir Crit Care Med 169: A559, 2004.

185. Gamble L, Quinton LJ, Wang G, Zhang P, Bagby GJ, and Nelson S: Primary human respiratory epithelial cell production of cytokines in response to Klebsiella pneumoniae and the effect of exposure to alcohol. Am J Respir Crit Care Med 169: A 564, 2004.

186. Mason CM, Dobard E, Badewa AP, Zhang P, and Nelson S: Effect of alcohol on locoregional lymphocytes in murine pulmonary TB. Am J Respir Crit Care Med 169: A754, 2004.

187. Quinton LJ, Nelson S, Zhang P, Happel KI, and Bagby GJ: Systemic administration of cytokine-induced neutrophil chemoattractant attenuates alcohol-induced suppression of pulmonary host defense. Am J Respir Crit Care Med 169: A805, 2004.


188. Zhang P, Zhong Q, Bagby GJ, Schwarzenberger PO, Wang G, and Nelson S: Alcohol inhibits granulocyte colony-stimulating factor induced proliferation of murine myeloid progenitor cells. Alcohol Clin Exp Res 28 (Supplement to 5): 37A, 2004.

189. Happel KI, Gamble L, Quinton LJ, Zhang P, Bagby GJ, and Nelson S: Klebsiella pneumoniae induced expression of IL-23 and IL-27 by alveolar macrophages is inhibited by acute ethanol. Alcohol Clin Exp Res 28 (Supplement to 5): 36A, 2004.

190. Quinton LJ, Nelson S, Zhang P, Gamble L, and Bagby GJ: Intratracheal CXC chemokine administration enhances the pulmonary neutrophil response to Klebsiella pneumoniae in rats with acute alcohol intoxication. Alcohol Clin Exp Res 28 (Supplement to 5): 36A, 2004.

191. Bagby GJ, Purcell J, Zhang P, Kolls J, and Nelson S: The longitudinal consequences of chronic-binge alcohol consumption on simian immunodeficiency virus (SIV) infected macaques. Alcohol Clin Exp Res 28 (Supplement to 5): 38A, 2004.

192. Gamble L, Quinton LJ, Happel KI, Zhang P, Bagby GJ, and Nelson S: The lipopolysaccharide binding protein response to intratracheal lipopolysaccharide. Am J Respir Crit Care Med (Abstract Issue) A70, 2005.

193. Happel KI, Dubin PJ, Zheng M, Ghirlardi N, Nelson S, and Kolls JK: IL-23 is critical to survival during pulmonary infection with Klebsiella pneumoniae. Am J Respir Crit Care Med (Abstract Issue) A306, 2005.

194. Zhang P, Zhong Q, Bagby GJ, Summer, WR and Nelson S: Inhibition of endotoxin-induced S100A8 production in the lung by acute alcohol intoxication. Am J Respir Crit Care Med (Abstract Issue) A367, 2005.

195. Happel KI, Mason CM, Lockhart E, Nelson S, and Ramsay AJ: Transient IL-23 over-expression improves early clearance of Mycobacterium tuberculosis. Am J Respir Crit Care Med (Abstract Issue) A449, 2005.

196. Zhang P, Quinton LJ, Gamble L, Bagby GJ, and Nelson S: The granulopoietic cytokine response and enhancement of granulopoiesis in mice during endotoxemia. Am J Respir Crit Care Med (Abstract Issue) A631, 2005.

197. Mason CM, Happel KI, Porretta E, Butler R, Welsh DA, Zhang P, Shellito JE, and Nelson S: Regulatory T cells in murine tuberculosis (TB). Proceedings of the American Thoracic Society 3:A218, 2006.

198. Zhang P, Bagby GJ, Engel LS, and Nelson S: Alcohol up-regulates p27kip1 expression and impairs the granulopoietic response to lung infection in mice. Alcohol Clin Exp Res 31 (Supplement to 6):219A, 2007.

199. Zhang P, Bagby GJ, Engel LS, and Nelson S: Alcohol impairs granulocyte mobilization from hematopoietic tissues in response to pneumococcal pneumonia. Alcohol Clin Exp Res 31 (supplement to 6):217A, 2007.

200. Kantrow SP, Shen Z, Jagneaux T, Zhang P, and Nelson S: Neutrophils and NADPH oxidase in lipopolysaccharide induced lung permeability. Am J Respir Crit Care Med (Abstract Issue) A175, 2007.


201. Happel KI, Zhang P, Bagby GJ, Dufour JP, and Nelson S: Chronic binge alcohol consumption by rhesus macaques may alter the T-helper cell cytokine profile toward IL-17. Alcohol Clin Exp Res 31(supplement):216A, 2007.

202. Mason CM, Porretta E, Zhang P, Ramsay A, and Nelson S: Alcohol and foxp3+ lung T cells in mice. Alcohol Clin Exp Res 31(supplement):219A, 2007.

203. Nelson S and Bagby GJ: The biomedical consequences of alcohol in the simian immunodeficiency virus (SIV) infected rhesus macaque model of HIV. Alcohol Clin Exp Res 31(supplement):262A, 2007.

204. Happel KI, Zhang P, Bagby GJ, and Nelson S: Alcohol and bacterial pneumonia: impairment of innate and adaptive immunity. Alcohol Clin Exp Res 31 (supplement):310A, 2007.

205. Bagby GJ, Dufour J, Zhang P, and Nelson S: Bacterial pneumonia increases viral load in the lungs of simian immunodeficiency virus infected rhesus macaques: effect of chronic alcohol consumption. Alcohol Clin Exp Res 32 (supplement):172A, 2008.

206. Kantrow SP, Shen Z, Zhang P, Ramsey J, and Nelson S: Acute alcohol intoxication, lung permeability and host defense. Alcohol Clin Exp Res 32 (supplement):172A, 2008.

207. Raasch CE, Bagby GJ, Nelson S, and Zhang P: Alcohol intoxication suppresses the Lin¯ C-Kit+ Sca-1+ cell response to pneumococcal pneumonia in mice. Alcohol Clin Exp Res 32 (supplement):173A, 2008.

208. Thomas JS, Lacour N, Nelson S, Bagby GJ, and Amedee AM: Using the SIV-infected rheuses macaque to examine the effects of chronic alcohol consumption on the HIV-inhibitory properties of saliva. Alcohol Clin Exp Res 32 (supplement):173A, 2008.

209. Zhang P, Bagby GJ, and Nelson S: Alcohol impairs G-CSF signaling in myeloid progenitor cell proliferation. Alcohol Clin Exp Res 32 (supplement):174A, 2008.

210. Siggins RW II, Nelson S, Welsh DA, Bagby GJ, Shellito JE, and Zhang P: Alcohol impairs the hematopoietic stem cell response to bacteremia. Alcohol Clin Exp Res 32 (supplement):174A, 2008.

211. Happel KI, Jeyaseelan S, Odden AR, Zhang P, Bagby GJ, and Nelson S: Acute ethanol intoxication impairs the pulmonary LIX response to endotracheal endotoxin. Alcohol Clin Exp Res 32 (supplement):224A, 2008.

Revised 01/27/09 KD


APPENDIX FOR IS-14a

LCME REPORT ONINSTITUTIONAL SETTING

Subcommittee 14aSchool of Medicine


Insert Appendix Material Here(Landscape Orientaion)


APPENDIX FOR IS-15

LCME REPORT ONINSTITUTIONAL SETTING

Subcommittee 15School of Medicine

Submitted by:

James Cairo, PhD, Dean of Allied Health


Proposed Funding, Translational Research Initiative Grant Proposals, FY 2009

New Proposals Funded Amount

1 – Bonny L. Dickinson, PhD and Eugene A. Woltering, MD, FACS“Human carcinoid tumor dysregulation of dendritic cell function” $60,000.00

2 – Tara L. Lin, MD and Yong Sung Choi, MD, PhD “Optimizing cancer stem cell targeted therapy in ALL” $60,000.00

3 – Sean Collins, MD and L. Joseph Su, MD “Prevalence of metabolic syndrome in the subjects of The North

Carolina/Louisiana prostate cancer project and the association with prostate cancer aggressiveness” $60,000.00

4 – L. Joseph Su, MD and Jodi Kamps, PhD “Folic acid supplementation during pregnancy and autism spectrum disorders” $49,000.00

5 – Yuwei Fan, PhD and Xiaoming Xu, PhD “Novel biomimetic remineralization dental materials for early dental caries treatment” $38,000.00

6 – Patricia E. Molina, MD, PhD and Lisa Moreno-Walton, PhD“Translational studies on the consequences of alcohol intoxication on outcome from traumatic injury” $65,000.00

7 – Erich Richter, MD, Theodore Weyand, PhD and Anne Foundas, MD “Neuromodulation of depressive affect in Rhesus monkeys” $60,000.00

8 – Jovanny Zabaleta, BS, MSc, PhD and Pelayo Correa, MD“Profiles of mRNA and micro RNA in gastric pre-malignant lesions” $60,000.00

9 – Bennet P. deBoisblanc, MD, David Welsh, MD, Nicole LeCapitaine, PhD “Microparticle networks in ARDS” $65,000.00

10 – Lolie C. Yu, MD, Yan Cui, PhD, Faisal Razzaqi, MD “Co-transfer of dendritic cell precursors and cytokine stimulation to accelerate immune recovery following hematopoietic stem cell transplant” $60,000.00

11 – Donna M. Neumann, Herbert E. Kaufman, MD “Epigenetic modifications regulation HSV-1 reactivation, efficiency, and frequency in an ocular model of herpes simplex keratitis” $60,000.00

12 – Jasmine Ellison, MD and William Gordon, PhD “Modulation of inflammatory signaling in an experimental


Academic Year _2007-2008_

animal model of uveitis: Potential therapeutic targets” $65,000.00

Supplements Funded Amount

1 – Walter J. Lukiw, MS, PhD, Frank Culicchia, MD and Jeff Erickson, PhD. Supplement – “Genetic regulatory mechanisms in growth and invasiveness of glioblastoma multiforme (GBM)” $60,000.00

2 – Kyle Happel, MD and Alistair J. Ramsay, PhD “Immunomodulation and pneumonia in HIV infection” $15,000.00(unspent FY 2008 funds: $46,775.00)

3 – Paulo C. Rodriguez, PhD, John Cole, MD and Augusto C. Ochoa, MD Supplement – “Arginase I, a molecular target for new treatment of T cell leukemia” $60,000.00

4 – Arnold Zea, PhD, Juzar Ali, MD, FRCP, FCCP and Carol Mason, MD Supplement - “The role of arginase and iNOS in Mtb growth-induced immunosuppression” $35,000.00

5 – Jian-Guo Cui, PhD and Gabriel C. Tender, MD Supplement – “The Role of VR1-positive neurons in central sensitization: Neuropathic pain management” $60,000.00

6 – Soledad M. Cortina, MD and Haydee E.P. Bazan, PhD - RenewalSupplement - “The role of pigment epithelial-derived growth factor (PEDF) and docosahexaenoic acid (DHA) in tear production and corneal nerve regeneration following refractive surgery” $60,000.00 (start date: upon Dr. Cortina’s appointment as a faculty member)

7 – Allal Ouhtit, PhD “Dysfunction of mesenchymal stem cell CD44 signaling in emphysema” $50,000.00

8 - Angela M. Amedee, PhD, Rebecca Clark, MD, PhD, David Martin, MD “Longitudinal analysis of HIV expression in women” $60,000.00

TOTAL $1,102,000.00



Basic Science Departments Collaborations (detailed examples)

TeachingDepartment of GeneticsCourse name/number Audience (school and

level)Examples of collaborative arrangements

Genetics(Med)

1st year Medical Students

Robin McGoey, MD Medical SchoolMike Marbell, MD Dept. of PedsPaula Gregory, PhD Genetics

Genetics through lifespan(Nursing)

Nursing School Gloria Giarrtano, PhD (Nursing School)Robin McGoey, Med SchoolPaula Gregory, PhD Genetics

Genetics in Physical Therapy

PT Students Jane Eason, PhD (Allied Health)Paula Gregory, PhD Genetics

Molecular Biology (INTER122/CMB-B)

1st year Graduate students

Andrew D. Hollenbach, Ph.D. – Course Director (Department of Genetics)Fern Tsien, PhD (Department of Genetics)Tadahide Izumi, Ph.D. (Department of Biochemistry)Ed Grabczyk, Ph.D. (Department of Genetics)Tomoo Iwakuma, M.D., Ph.D. (Department of Genetics)

Control of Gene Expression (INTER123/CMB-C)

1st year Graduate students

Andrew D. Hollenbach, Ph.D. – Course Director (Department of Genetics)Fern Tsien, Ph.D. (Department of Genetics)Tomoo Iwakuma, M.D., Ph.D. (Department of Genetics)Diptasri Mandal, Ph.D. (Department of Genetics)Ed Grabczyk, Ph.D. (Department of Genetics)Paula Gregory, Ph.D. (Department of Genetics)

Genetic Epidemiology & Population Genetics (GENET 236)

Graduate students Diptasri Mandal, PhD (course director)

Genetics (SPTHAUD 7225)

Audiology graduate students

Fern Tsien, PhD (Genetics)

Practical BioinformaticsGENET 256

Graduate students Genetics (Grabczyk, leader)

Genetics/SPTHAUD7225 LSUHSC School of Allied Health ProfessionsDoctor of Audiology

Fern Tsien, PhD, course director, Genetics LSUHSCDiptasri Mandal, PhD, Genetics, LSUHSCChris Dvorak, MS, Genetics, Tulane HSC

Research Methods/HMGN 795

Tulane Medical School

Medical studentsGraduate students

Karen Weissbecker, PhD, Course director, Genetics, Tulane HSC



Department of Anatomy

Human Prenatal Development

Medical Students-first year

Pediatrics: Dr. Barkemeyer; ObGyn: Drs. Holman, Curole; Pathology: Dr. McGoey

Medical Gross Anatomy Medical Students-first year

Surgery: Drs. Hollier,Paige; ENT: Drs. McWhorther, Nuss, Pou, Lin, Zuzukin, Valvekar; Radiology: Dr. Landry; Orthopedics: Drs.Omotola,Sisco; Emergency Medicine: Several Residents in ER; Ob/Gyn: Dr. Bedastani

Genetics: Dr. Gregory

Medical Neuroscience Medical Students-first year

Neurology: Drs.Deputy,England, Foundas, Gould,Gutierrez, Tilton; Neurosurgery: Drs. Owen, Culicchia,Dawson,Richter, Tender; NeuroscienceCenter: Dr. Bazan

Senior Surgical Anatomy Elective

Medical Students-4th year

Surgery: Drs. Hollier,Baker, Sheahan, Wang, Paige, Steeb, Marr, Hunt; Radiology: Dr. Chalpin; Pathology: Drs.McGoey,Troxclair,Lipscomb, Springer; ENT: Dr.Pou; Ob/Gyn: Drs.Brewer, Ibeanu; Orthopedics: Dr. Murphy

Department of Pharmacology

Medical Physiology 1st year medical studentsNurse anesthetistsGraduate students

Jimmy Cairo, PhD Ben DeBoisblanc, MD

School of Allied HealthDepartment of Medicine

Medical Pharmacology/ 2nd year medical studentsGraduate Students

Bob Richards – MedicineBen deBoisblanc – MedicineCharles Sanders – MedicineDeborah Fox –MIPJeff Hobden - MIPJames Hill – OphthalmologySteve Kantrow – MedicinePaula Gregory – GeneticsHarry Gould – NeurologyAlan Kaye – AnesthesiologyCharles Cefalu – Geriatric MedicineKim Leblanc – Family MedicineVictor Tuckler - Medicine



Department of Biochemistry

Integrated Graduate Curriculum (Cell Biology & Development)

1st year graduate students

The Biochemistry faculty collaborates with faculty from other basic science departments in team teaching this first year course for the Graduate School of Biomedical Sciences for which Dr. Andrew Catling is course director.

Medical Pharmacology 1st year medical students Drs. Alahari and Desai contribute lectures to this team taught Pharmacology Department medical course.

Medical Biochemistry 1st year medical students The course is team taught by 8 members of the Biochemistry faculty, each of which focuses on their particular area of expertise.

Department of PhysiologyMedical Physiology 100Nursing 8301

Medical school L1 level

Nursing grad level

Physiology faculty: Levitzky, Molina, McDonough, Harrison-Bernard, Potter, Porter, GiaimoJimmy Cairo – Dean Allied HealthBen DeBoisblanc – MedicineWarren Summer – MedicineJuzar Ali – MedicineDuna Penn – Pediatric MedicineWilliam Cefalu - MedicineJohn Zamjahn – Allied health - CPS

Dental Physiology 1115 Dental School1st year

Physiology faculty: Porter, Giaimo, Breslin, GardnerHappel - NeurologyEmeritus professors of Physiology : Liles, Nakamoto

Dental Hygiene 3202 Dental School 1st year

Physiology faculty: Harrison-Bernard Breslin, Gardner,Emeritus professor of Physiology : Liles

N-HLS2410AH-OCCT 6523

Nursing School 1st yearAllied Health School 1st year

Physiology faculty: Shepherd, Potter, GardnerAndrew Pellett – Allied health – CPSJohn Zamjahn – Allied health – CPSVicki Jordan - Nursing

N-Nursing HLSC 3410 Nursing School2nd year

Physiology faculty: Shepherd, Potter, Gardner, Levitzky, Molina, McDonough, PorterJohn B. Zamjahn, PhD - Allied Health - CPSDebbie Garbee, PhD- NursingVickie Jordan, PhD, CRNA – NursingPhyllis Peterson, PhD– NursingDemetrius Porche, Dean Nursing SchoolMiroslav Sarac, PhD - Xavier UniversityAlbert J. Swafford, PhD - Our Lady of Lake

N-Care HS 3410 Nursing School 2nd year Physiology faculty: Shepherd, Potter, Gardner, Levitzky, Molina, McDonough, PorterJohn B. Zamjahn, PhD - Allied Health - CPS



Debbie Garbee, PhD- NursingVickie Jordan, PhD, CRNA – NursingPhyllis Peterson, PhD– NursingDemetrius Porche, Dean Nursing SchoolMiroslav Sarac, PhD - Xavier UniversityAlbert J. Swafford, PhD - Our Lady of Lake

G-INT132

G-INT 132 (AH DPT)Graduate school1st year

Physiology faculty: Shepherd, Potter, Gardner, Levitzky, Molina, McDonough, Porter, Harrison-Bernard, BagbyDan Kapusta – PharmacologyPaula Gregory – GeneticsRichard Tracy – PathologyHamilton Farris – Neuroscience

M-Medical Spanish PHSY220a

Medical School 1st year Physiology Faculty : Molina

G-INTER217 History and Philosophy of Medical Research

Graduate School Physiology Faculty : Potter

G Special Topics PHYS 281 PAR

Graduate School Physiology faculty: Molina, BagbyPing Zhang – Medicine

Science and Practice of Medicine 100 (DXR)

Medical School 1st year 2nd year

Levitzky, McDonough

Department of Microbiology

Medical Microbiology 2nd year medical students

James Thompson, PhD, Director - MicrobiologyBonny Dickinson PhD Children’s HospitalJulio Figueroa, MD Department of MedicineDipon Dixit, PhD Pennington CenterTom Gillis, PhD Hansen’s CenterMike Hagensee,MD,PhD Department of MedicineDavid Martin, MD Department of MedicineLee Engel, PhD,MD Department of MedicineToby Rodriguez,PhD School of DentistryJoAnne Maffei,MD Department of MedicineWilliam Cassidy,MD Department of MedicineCharles Sanders,MD Department of Medicine

Microbiology Dental Hygiene [3201course]

1st year dental hygiene students

Microbiology (Johnston, Director)Dental School (Palmer)

Advanced Bacteriology Graduate Students Microbiology (Hobden, Director)Microbiology (Johnston)

Molecular Biology of Eukaryotic Pathgins (MIP231)

Graduate Students Microbiology (Sturtevant, Director)Dental School (Palmer)Pediatrics (Cutler, Fox, Wang)

Medical Pharmacology Medical students Microbiology (Koochekpour, Hobden)



ResearchDepartment of GeneticsActivity/project Departments or schools involvedRCEEP Grant BOR Tulane HSC (Hamou)( Weiner)( Delafontaine)

LSU HSC- Medical (Nelson) Genetics (Gregory) Pediatrics (Pincus)

LGTRC Tulane HSCLSUHSC-Genetics (Gregory) Gene Therapy (Ramsay)

The Role of phosphorylation in the development of the solid muscle tumor alveolar Rhabdomyosarcoma, Junior investigator on the Cancer Genetics COBRE award

Tulane Medical School – Epidemiology (Deininger,PI) Epidemiology (Engel) Microbiology (Scandurro)

LSUHSC – Genetics ( Keats, Co-PI) Genetics ( Hollenbach) Genetics (Iwakuma)

Determination of Genetic Susceptibility to Lung Cancer

Washington University, St. Louis, Missouri;Mayo Clinic, Rochester, MinnesotaUniversity of Cincinnati, Cincinnati, OhioUniversity of Colorado, Denver, ColoradoKarmanos Cancer Institute, Detroit, MichiganUniversity of Toledo College of Medicine,Toledo, OhioSaccomanno Research Institute, Grand Junction, ColoradoNational Human Genome Research InstituteM. D. Anderson Cancer Center, HoustonNational Cancer Institute, Bethesda, Maryland, USA

Genetic Characterization of Prostate Cancer

National Human Genome Research InstituteDepartment of Genetics/Tulane University School of MedicineDepartment of Medicine and Urology/Tulane Medical SchoolMD Anderson Cancer Center, Houston

Analysis of Endometriosis Candidate Genes

Department o Microbiology/Ponce School of Medicine, Puerto Rico

Mechanisms contributing to frataxin deficiency, RO1, NINDS-funded

Genetics, LSUHSC (Grabczyk, PI)

The roles of MTBP in osteosarcoma metastasis

Genetics, LSUHSC (Iwakuma, PI)Genetics, LSUHSC (Tsien,)

Characterization of multipotent mesenchymal stem cells from the bone marrow of rhesus macaques

Tulane Primate Center (Bunnell, PI)Genetics, LSUHSC (Tsien)



Center for Acadiana Genetics and Hereditary Health Care (CAGHHC)

LSUHSC (Keats and Kolls, PIs)LSUHSC (Tsien)Tulane HSC (Andersson)Nicholls State University,Thibodeaux LA ( Doucet)

Crosstalk between IL-7Rα signaling and p53 pathway in maintaining chromosomal stability during thymopoiesis and preventing lymphomagenesis

Gene Therapy (Yan Cui, PI)Genetics (Tsien)

The roles of MTBP in osteosarcoma metastasis

Genetics ( Iwakuma; Liu)Orthopedics (S Heinrich)Bioinformatics ( Velasco-Gonzalez),Pathology ( Ruiz)

The role of mutant p53 in the properties of osteosarcoma stem cells

Genetics (Iwakuma; Liu)Orthopedics (Heinrich)Bioinformatics (Velasco-Gonzalez),Pathology (Ruiz)

DNA Damage-Response Defects and Prostate Cancer Susceptibility

Microbiology & Cancer Center (Koochekpour)Genetics ( Liu)

The Role of AXIN2 in Colorectal Cancer Development

Genetics & Cell Biology (Wessely)Genetics (Liu) Animal care (Birke)

CD8 T-CELLS AND Host Defense against P. carinii Pneumonia

Genetics (Kolls, PI)Medicine (Shellito)

IL-23/IL-17 and Lung Host Defense

Genetics (Kolls, PI)Medicine (Happel)

Host Defense against HIV-related pulmonary infections

Genetics (Kolls Project 2)Medicine (Shellito Project 1)Gene Therapy (Ramsay Project 3)

Alcohol, ROS, and Macrophage Epigenetics

Genetics (Kolls, PI)Physiology (Bagby)Physiology (Zhang)Medicine (Happel)

Department of Pharmacology

Seminar series Physiology/PharmacologyJournal Club Physiology/Pharmacology

Cardiovascular Center Seminar program (COBRE)

Pharmacology, Physiology, Pathology, Biochemistry, Surgery

Medical Student Summer Research

Basic Science and Clinical Science Depts. and the 1st year Medical Students



Medical Student Honors program

Basic Science and Clinical Science Depts. and Medical Students

THC impact on SIV progression RO1, NIDA-funded

Physiology (Molina, PI)Pharmacology (Winsauer, Varner)Microbiology (Amedee)Animal Care (Birke)Pathology (Zieske, Troxclair)

“Mentoring in Cardiovascular Biology”, COBRE Grant, NI

Pharmacology : (Kapusta, PI, Varner, Cormier, Lazartigue, Songu-Mize, Guidry, Wu, Wainford, Worthylake, Boulares, Filipeanu)Physiology: (Molina, Breslin, Harrison-Bernard, Gardner)Biochemistry: (Claycomb)Pathology: (Strong, Troxlair)Surgery: (Bazan)

Department of BiochemistryBioinformatics and statistics

Xiaogeng Feng MS, our Bioinformatics Specialist, collaborates with a number of investigators from Biochemistry and other departments in the School of Medicine on bioinformatic projects involving protein and gene sequence analysis in addition to software development.

Structural biology Drs. Chiu and Worthylake individually collaborate with a number of investigators from the School of Medicine on projects to determine the structure of specific proteins including: Ben Kelly (MIP), Sunyoung Kim (Biochemistry), Ed Wojcik (Biochemistry), Sunyoung Kim (Biochemistry), Suresh Alahari (Biochemistry), and Andrew Catling (Pharmacology). These collaborations have resulted to date in two submitted grant applications (Kelly and Catling).

Cancer and neurological disorders

Dr. Desai is collaborating with Augusto Ochoa (Cancer Center) and J. Rao (Ochsner Foundation Clinic) on the role of ISG15 in cancer progression and Parkinson’s disease, respectively.

Cancer research Dr. Alahari collaborates with several investigators on the etiology of breast cancer: Robin McGoey (Pathology), Donald Mercante (Biostatistics), Andrew Catling (Pharmacology), Becky Worthylake (Pharmacology), Tomoo Iwakooma (Genetics)

Department of PhysiologySeminar series Physiology/PharmacologyJournal Club Physiology/PharmacologyCardiovascular Center Seminar program (COBRE)

Physiology, Pharmacology, Pathology, Biochemistry, Surgery

Medical Student Summer Research

Basic Science and Clinical Science Depts. and the 1st year Medical Students

Medical Student Honors program

Basic Science and Clinical Science Depts. and Medical Students


Physiology (Molina, PI)Pharmacology (Winsauer, Varner)Microbiology (Amedee)



Animal Care (Birke)Pathology (Zieske, Troxclair)

“Mentoring in Cardiovascular Biology”, COBRE Grant, NI

Physiology: (Molina, Breslin, Harrison-Bernard, Gardner)Pharmacology : (Kapusta, PI, Varner, Cormier, Lazartigue, Songu-Mize, Guidry, Wu, Wainford, Worthylake, Boulares, Filipeanu)Biochemistry: (Claycomb)Pathology: (Strong, Troxlair)Surgery: (Bazan)

Regulation of Coronary Collateral Growth in Metabolic Syndrome

University South AlabamaLSU HSC- Physiology (Potter)

Department of MicrobiologyLongitudinal Analysis of HIV Expression in Women – Translational Research Initiative

Microbiology (Amedee, PI)Medicine/Infectious Disease (Martin, Mentor)Tulane/Dept of Medicine (Clark, Clinician)

Mucosal Cell Mediated Immunity in Vaginal Candidiasis, R01, NIAID

Microbiology and School of Dentistry (Fidel, PI)

Mechanisms of Herpes Virus Proteins in Hijacking and Subverting Host and Cellular Response Pathways – BOR LEQSF

Microbiology (Foster, PI)Gene Therapy (Ramsay)Pharmacology (Cormier)

Endocervical Chlamydia Trachomatis Infection; is there evidence of persistence? – Translational Research Initiative

Microbiology (Quayle, PI)Pathology (Ruiz, Strong)Medicine/Infectious Disease (Martin)OB/GYN (Dildy, Nolan)UTHSC, Molecular Sciences (Belland)

Gulf South STI/Topical Microbicide Cooperative Research Center – U19, NIAID, Project 1

Microbiology (Quayle, PI – Project 1)Medicine/Infectious Disease (Martin)University of Missouri (Schust)

Signaling Complexes and the 14-3-3 Protein in Candida, R01, NIAID

Microbiology (Sturtevant, PI)School of Dentistry (Palmer, Fidel)Pediatrics (Cutler)UTHSC (Lorenz)

South Louisiana Institute for Infectious Disease Research – BOR, RCEEP

Microbiology and School of Dentistry (Fidel, PI)Medicine/Infectious Disease (Martin, Co-PI, Hagensee)TUHSC, Microbiology (Clements, Co-PI)Microbiology (Hobden, Luftig, Quayle, Shen, Amedee, Zhong)Anatomy and School of Dentistry (Lallier)Office of Technology Development (Ceulemans)Gene Therapy (Ramsay)



Pediatrics (Cutler, Pincus, Pishardy, Ferris, Penn)Medicine/Pulmonary (Shellito)Opthalmology (Hill)School of Dentistry (Wen)

Dental School COBRE, NCRR

School of Dentistry (Fidel, PI)Microbiology (Sturtevant, Luftig - both as mentors)

Research Institute at Children’s Hospital COBRE, NCRR

Pediatrics (Cutler, PI)Microbiology (Sturtevant, Co-PI and Mentor)

Discovering New Anti-Leishmania Therapies by Targeting Leishmania Signaling Pathways Required for Virulence, DOD

Microbiology (Kelly, PI)Biochemistry (Chiu

Development and Evaluation of Student Competency Measures

Microbiology (Thompson – PI)Office of Medical Education and Research

Alcohol Research Center Medicine/Pulmonary (Nelson – PI)Microbiology (Amedee)


Physiology (Molina, PI)Microbiology (Amedee)

Antibody Affinity Maturation

Pediatrics (Pincus – PI)Microbiology (Aiyar)

Bacterial Keratitis Microbiology (Hobden)LSU Ag Center (Liu)

Bacterial Biofils on Artificial hip and knee joints

Microbiology (Hobden)Orthopedics (Vinod)

ServiceDepartment of GeneticsStrategic Planning, Communications workgroup

Physiology (Molina, leader)Pathology (Venuti)Genetics (Hollenbach)OB/Gyn (Brewer)Anatomy (McClugage)Psychiatry (Osofsky)Neuroscience Center (Bazan)LSU Alumni (Klein)LSU Foundation

Strategic PlanningFaculty Development Workgroup

Neurosurgery (Richter)PharmocologyPath (McGoey)Phys. (Levitsky)BiochemistryInt. Med (Launders)



Genetics (Gregory)Med SchoolCurriculumCommittee

Anatomy ( Schwartz)Physiology (Levitsky; McDonough)Family Medicine (Le Blanc)Neurosurgery (Richter)OB/GYNGenetics (Gregory)

LSUHSC Committee on Women’s Affairs

Genetics (Gregory, Tsien)Medicine (McLean, Sanders, Clark, Subramaniam, Besch, Kumari, Hebert, Murphey-LaVoie, Cui)Anatomy (Delcarpio)Pediatrics (Velez, Yu, Olister, Albrecht, Rivera, Lo-Blais, Sadowska-Krowicki, Mangat)Pharmacology (Songu-Mize, Worthylake)Neurology (Gutierrez)Ophthalmology (Jacob, Canavier)OB/Gyn (Chau, Truehill, Holman)Pathology (Espinosa)MIP (Amadee, Luftig)BioChemistry (Huh)Med/Peds (McDermott)Psychiatry (Many)Cell/Bio (Venuti)Dean’s Office (Letourneau)

LSUHSC Faculty Assembly

Various clinical and basic research faculty representatives for each department within LSUHSCGenetics (Hollenbach, Andrew)

Graduate Advisory Council

School of Medicine LSUHSC Graduate SchoolBiochemistry (Alahari, Haas, Kim)MIP (Amedee, Hobden)Physiology (Bagby, Levitzky, McDonough)Pharmacology (Catling, Nichols, Songu-Mize)Neuroscience (Erikson)Biostatistics (Fang, Mercante)Anatomy (Lallier, Mize, Venuti, Weyand)Pathology (Sakamuro, Scheer)Neuroscience (Erikson)VC for Academic Affairs (Moers)

Curriculum Committee Graduate SchoolChairperson (Mandal)Biostatistics (Mercante)Physiology (Molina)Pharmacology (Songu-Mize) Anatomy (Weyend)



Council on Professional Conduct

Genetics (Mandal)School of MedicineChancellor (Gardner)Med (Herbert, Wilcox)Med/Pul (Kantrow, Mason)Anat/Cell (Lallier, Whiworth)Phys iology (Levitzky)Dean/Anat (McClugage)Pediatrics (Lo-Blais)Med/Id (Taylor)

Institutional Biosafety Committee

Microbiology, Immunology & Parasitology (Thompson, leader)Biochemistry (Alahari)Pharmacology (Catling) Genetics (Grabczyk)Opthalmology (Jacob)Environmental Health & Safety (Pourciau, Troxler)

Area Health Education Centers (AHEC)

LSUHSC (Tsien)Tulane HSC (Anderson)Nicholls State University,Thibodeaux LA (Doucet)

Member of the junior faculty mentoring committee in Stanley S. Scott Cancer Center, LSUHSC

Cancer Center (Ochoa)Genetics (Liu)

Member of the Tissue Utilization Review Committee in LCRC

Cancer Center (Paz)Genetics (Liu)

Department of PharmacologyStrategic Planning, Communications workgroup

Physiology (Molina, leader)Pathology (Venuti)Genetics (Hollenbach)OB/Gyn (Brewer, Holman)Anatomy (McClugage)Psychiatry (Osofsky)Neuroscience Center (Bazan)LSU Alumni (Klein)LSU Foundation

Department of BiochemistryStrategic Planning, Communications workgroup

Physiology (Molina, leader)Pathology (Venuti)Genetics (Hollenbach)OB/Gyn (Brewer, Holman)Anatomy (McClugage)



Psychiatry (Osofsky)Neuroscience Center (Bazan)LSU Alumni (Klein)LSU Foundation

Department of PhysiologyStrategic Planning, Communications workgroup

Physiology (Molina, leader)Pathology (Venuti)Genetics (Hollenbach)OB/Gyn (Brewer)Anatomy (McClugage)Psychiatry (Osofsky)Neuroscience Center (Bazan)LSU Alumni (Klein)LSU Foundation

Strategic PlanningFaculty Development Workgroup

Neurosurgery (Richter)PharmocologyPath (McGoey)Phys. (Levitsky)BiochemistryInt. Med (Launders)Genetics (Gregory)

Med SchoolCurriculumCommittee

Anatomy ( Schwartz)Physiology (Levitsky; McDonough)Family Medicine (Le Blanc)Neurosurgery (Richter)OB/GYNGenetics (Gregory)


School of Medicine LSUHSC Graduate SchoolBiochemistry (Alahari, Haas, Kim)MIP (Amedee, Hobden)Physiology (Bagby, Levitzky, McDonough)Pharmacology (Catling, Nichols, Songu-Mize)Neuroscience (Erikson)Biostatistics (Fang, Mercante)Anatomy (Lallier, Mize, Venuti, Weyand)Pathology (Sakamuro, Scheer)Neuroscience (Erikson)VC for Academic Affairs (Moers)

Curriculum Committee Graduate SchoolChairperson (Mandal)Biostatistics (Mercante)Physiology (Molina)Pharmacology (Songu-Mize) Anatomy (Weyend)



Council on Professional Conduct

Genetics (Mandal)School of MedicineChancellor (Gardner)Med (Herbert, Wilcox)Med/Pul (Kantrow, Mason)Anat/Cell (Lallier, Whiworth)Phys iology (Levitzky)Dean/Anat (McClugage)Pediatrics (Lo-Blais)Med/Id (Taylor)

LSUHSC Faculty Assembly

Various clinical and basic research faculty representatives for each department within LSUHSCPhysiology (Porter, Bagby, Levitzky)

IACUC Physiology (Bagby, Molina)ACAC Physiology (Bagby, Molina)Search for Head of Pathology

Physiology ( Molina)

Department of MicrobiologyFaculty Assembly Microbiology (Sturtevant, MIP representative)Strategic Planning: Research and Core Facilities

Gene Therapy (Ramsay – Chair)Microbiology (Kelly, Foster, Aiyar)

Radiation Safety Committee

Microbiology (Koochekpour, Aiyar – members)

Institutional Biosafety Committee

Microbiology (Thompson – Chair)

Teaching Academy Scholarship Committee

Microbiology (Thompson – Chair)

Faculty Senate Microbiology (Amedee – Member)Constitution and Bylaws Committee (Faculty Senate)

Microbiology (Amedee – member)


Microbiology (Amedee, Hobden – members)

Postdoctoral Fellow Committee (Graduate Advisory Council)


Pharmacology Chair Search Committee


N.O. Public School Outreach Program (Graduate School)

Microbiology (Amedee – participant)

Research Enhancement Fund Committee

Microbiology (Aiyar)

LCME Prep Committee Microbiology (Hobden)Pre-Clinical Promotions Microbiology (Hobden)



Committee



END OF SECTION I


Documents

FUNCTIONS AND STRUCTURE OF A MEDICAL …€¦ · Web viewApril 3, 2009. GENERAL INSTRUCTIONS FOR COMPLETING THE DATABASE. Each question in the database is preceded by the relevant