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    Frudensia Kristiana

    405110031

    Group 10

    Problem 5“Emergency Medicine Bloc!

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    "iagnosis Multia#ial$PP"% &&&'

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    "a(tar Kategori "iagnosisF0 ) Gangguan Mental *rgani+ ,ermasu Gangguan Mental

    -imtomati

    F1 ) Gangguan Mental dan Perilau .ibat Penggunaan /at Psioati( F10 ) Gangguan mental dan perilau aibat penggunaan aloolF11 ) Gangguan mental dan perilau aibat penggunaan opioidaF1 ) Gangguan mental dan perilau aibat penggunaan anabinoida

    F13 ) Gangguan mental dan perilau aibat penggunaan sedati2a atauipnotiaF14 ) Gangguan mental dan perilau aibat penggunaan oainF15 ) Gangguan mental dan perilau aibat penggunaan stimulansia lain

    termasu a(einF1 ) Gangguan mental dan perilau aibat penggunaan alusinogenia

    F1 ) Gangguan mental dan perilau aibat penggunaan tembaauF1 ) Gangguan mental dan perilau aibat penggunaan pelarut yang

    muda menguapF16 ) Gangguan mental dan perilau aibat penggunaan 7at multipel

    dan penggunaan 7at psioati( lainnya

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    F ) -i7o(renia+ Gangguan -i7otipal dan Gangguan8aam

    F3 ) Gangguan -uasana Perasaan

    F4 ) Gangguan 9euroti+ Gangguan -omato(orm danGangguan yang beraitan dengan -tres

    F5 ) -indrom Perilau yang Berubungan denganGangguan Fisiologis dan Fator Fisi

    F ) Gangguan Kepribadian dan Perilau Masa "e:asa

    F ) ;etardasi Mental

    F ) Gangguan Perembangan PsiologisF6 ) Gangguan Perilau dan Emosional dengan *nset

    Biasanya pada Masa Kana dan ;ema

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    "iagnosis Multiasial

    •  ,u

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    .#is &Gangguan Klinis $F00>06+ F10>6+ F0>6+ F30>36+ F40>

    4+ F50>56+ F>+ F0>6+ F60>6+ F66'Kondisi ?ain yang Men6'$tida ada diagnosis /03=+ diagnosis tertunda ;4='

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    .#is &&&Kondisi Medi @mum

    .#is &A

    Masala Psiososial dan ?ingungan$eluarga+ lingungan social+ pendidian+peer

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    .#is A

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    .#is A Penilaian Fungsi -ecara Global $Global .ssesment o( Functioning G.F -cale' 100>61 ge1 ge1 ge1 bbrp ge51 ge41 ge31 bbrp disabilitas dlm ubungan dgn realita C omuniasi+ disabilitasberat dlm beberapa (ungsi

    30>1 disabilitas berat dlm omuniasi C daya nilai+ td mampu ber(ungsi

    dlm ampir semua bidang 0>11 baaya mencederai diriDorang lain+ disabilitas sangat berat dlm

    omuniasi C mengurus diri

    10>01 persisten dan lebi serius

    0 in(ormasi tida adeuat

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    "rug abuse

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    ommon "rugs o( .buse

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    *pioid

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    *pioid Eect

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    ttp)DD:::=ncbi=nlm=ni=go2Dboosel(Dpicrender=(cgiHboossamsatipCpart.4566Cblobnametip54aIg=

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    Jallucionogen

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    annabis

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    Jo: to @seH

    -moed  euporic eects in minutes+Pea ) 30 minutes+?asts ) >4 ours+

    Motor C cogniti2e eect ) 5>1 ours

    *rally  bro:nies+ caes= >3 times dose toacie2e same eect as smoed=

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    .mpetamine

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    "-M &A>,; ;&,E;&. F*;.MPJE,.M&9E &9,*&.,&*9

    Kaplan and -adocLs -ynopsis o(

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    "-M &A>,; ;&,E;&. F*;.MPJE,.M&9E 8&,J";.8.?

    Kaplan and -adocLs -ynopsis o(

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    Jypnotics+ -edati2es+.n#iolytics

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    &nto#ication and 8itdra:al

    Kaplan and -adocLs Pocet Jandboo o( linical

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     ,reatment o( Ben7odia7epine8itdra:al

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    .lcool

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    "-M>&A>,; "iagnostic riteria (or.lcool 8itdra:al

    .= essation o( $or reduction in' alcool use tat as been ea2yand prolonged

    B= ,:o $or more' o( te (ollo:ing+ de2eloping :itin se2eralours to a (e: days a(ter riterion .)

      1= autonomic yperacti2ity $e=g=+ s:eating or pulse rategreater tan 100'

      = increased and tremor  3= insomnia  4= nauseaD2omiting  5= transient 2isual+ tactile+ or auditory allucinations or

    illusions  = psycomotor agitation

      = an#iety  = grand mal sei7ures

    = ,e symptoms in riterion B cause clinically signiIcantdistress or impairment in social+ occupational+ or oterimportant areas o( (unctioning

    "= ,e symptoms are not due to a general medical condition andare not better accounted (or by anoter mental disorder

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    9icotine

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    aeine

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    Withdrawal Symptoms Intoxications

    Headache $o(ten described asbeing gradual in de2elopment

    and diuse+ and sometimestrobbing and se2ere'Fatigue >> $e=g=+ (atigue+tiredness+ letargy+ sluggisness'Sleepiness/drowsiness >> $e=g=+sleepy+ dro:sy+ ya:ning'

    Difculty concentrating >>$e=g=+ mu77y'Work difculty >> $e=g=+decreased moti2ation (ortassD:or'Irritability >> $e=g=+ irritable+

    cross+ miserable+ decreased :ell>beingDcontentedness'Depression >> $e=g=+ depressedmood'Anxiety >> $e=g=+ an#ious+ner2ous'

    Flulike symptoms >> $e=g=+nauseaD2omiting+ muscle

    ner2ousness $an#iety'+restlessness+

    e#citement+insomnia+rambling No: o( tougt andspeec+gastrointestinal upsetremors+

    tacycardia+diuresis+muscle t:itcing+periods o( ine#austibility+ andpsycomotor agitation=

    &n addition+ tere a2e beenreports o( patients :it caeineinto#ication a2ing (e2er+irritability+ tremors+ sensorydisturbances+ tacypnea+ andeadaces= Jig dose caeine

    to#icity is 2ery rarely (atal=Jo:e2er+ caeine can be letal at

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    Psyciatry Emergency

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    "-M > &A

    ;ecent ingestionBea2ior canges $e=g= aggression'

    -lurred speec

    oordination

    @nsteady gait

    9ystagmus

    O .ttention or memory

    -tupor or coma

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    -upport Aital -igns

    Measure 2ital signs (reuently.ddress li(e>treatening problems  .Bs

    *( Emergency are

    9o medication until are sure tey are

    needed

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    .ir:ay and Breating

    .ssure adeuate 2entilation-traigten ead $i( no nec in

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    irculation

    Maintain adeuate blood pressure-tart &A line@se large>gauge needle

    @se a slo: drip until no: i( need Nuids

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    -peciIc "rugs ) .ntidotes

    *pioids R nalo#oneMonitor possible opioid abstinence syndrome

    B"/ R Numa7enilMonitor possible sei7ures C S intracran press

    .tropine>lie drugsR pysostigmine

    Barbiturates R 9o antidoteForced diuresis C alalini7ation o( urine

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    GE*ME,;&.? J.?@&9.,&*9

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    Brain &n2ol2ement

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    Jeroin

    Jeroin enters te brain+ con2erted tomorpine+ binds to opioid receptors$located in brain+ body+brainstem'  aectsperception o( pain+ and alter breating+ BP+

    J;+ arousal+ etc;egular eroin use  tolerancedecreased pysiological andpsycological eect o( drug  more eroin

    needed to reac te same intensity o(eect

    9ational &nstitute on "rug .bu

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    9ational &nstitute on "rug .bu

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    Mari

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    ?-"

    "isrupting interaction o( ner2e cells andneurotransmitter serotonin  impairscontrol o( bea2ioral+ perceptual+ andregulatory systems+ including mood+

    unger+ body temperature+ se#ualbea2ior+ muscle control+ and sensoryperception

    &mpairs glutamate receptors  impairs

    perception o( pain+ responses to teen2ironment+ and learning and memory=

    9ational &nstitute on "rug .bu

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    .mpetamine

    Binds to serotonin transporter

     prolongedserotonin signal

    Enters serotonergic neurons  releasemore serotonin

    -erotonin is a neurotransmitter tat playsan important role in te regulation o( mood+sleep+ pain+ appetite+ and oter bea2iors=

    9ational &nstitute on "rug .bu

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    Metampetamine

    &ncreases te release and bloc tereuptae o( dopamine  euporia

    ronic abuse  reduced motor sills andimpaired 2erbal learning+ se2ere structural

    and (unctional canges in areas o( tebrain associated :it emotion and memory cogniti2e and emotional problems

    9ational &nstitute on "rug .bu

    -edati2es+ Jypnotics+

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    -edati2es+ Jypnotics+.n#iolytics

    Binds to G.B.. receptors

     increaseaTnity to G.B.  increase te No: o(cloride ions torug te cannel into teneuron

    G.B. stimulation results less cloride inNutan :as caused by G.B. stimulationbe(ore ben7odia7epine administrations  tolerance and dependence

    Kaplan and -adocLs -ynopsis o(

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    Ecstasy

    Binds to serotonin transporter

     prolongedserotonin signal

    Enters serotonergic neurons  releasemore serotonin

    ?esser eect in dopamine.(ter drugs use ) con(usion+ depression+

    sleep problems+ drug cra2ing+ and se2erean#iety

    ronic ) impairs cogniti2e ability

    9ational &nstitute on "rug .bu

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    .lcool

    9o single molecular targetsEects on membranes o( neurons-ort term ) increasing Nuidity o( te

    membranes

    ?ong term ) membranes become rigi

    Kaplan and -adocLs -ynopsis o(

    JarrisonLs Principle o( &nternal Medicine 1t Ed

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    .lcoolLs .ect on te Brain

    Alcoholism shrinks the brain 

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    "iagnosis

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    Eyes8atering eyes occur during opiate :itdra:al=

    Pin>point pupils suggests te recentadministration o( opiates=

    "ilated pupils occurs in opiate :itdra:al+ and:ic also occur (ollo:ing te use o(ampetamine+ cocaine+ allucinogens $?-"'+ andanticolinergic drugs $in some *, drugs'=

    9ystagmus is indicati2e o( into#ication :it

    sedati2e ypnotics;ed eye $dilatation o( con

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    Mout"ental caries is (reuently (ound in opiate

    dependent users $due to poor dental ygieneand predilection (or s:eet (ood'=

    ?oss o( se2eral teet may occur in te courseo( con2ulsions during sedati2e ypnotic:itdra:al=Breat odour may indicate sol2ents or

    alcool abuse=

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    -inGooseNes $pilo>erection' indicates opiate

    :itdra:al=Pro(use s:eating indicates :itdra:al (rom

    sedati2e>ypnotics and alcool=-cars o( abscesses o2er any:ere o( te

    body

    9eedle puncture mars in te sin o2erlying

    te 2eins o( in

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    9euromuscular system ,remor and muscle t:itcing are signs o(

    opiate :itdra:al=-e2ere :asting o( te muscle occurs :en

    drug lie petidine is repeatedly in

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    ?aboratory E#amination

    "rug test lab management include)-creening test-ee te presence D absence o( te substance D

    metabolite

    Kno:ing te type o( substance D metabolitecontained-etting presence D absence complications

    due to drug use

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    ?aboratory metod (or screening drugs and ismetobolit must a2e te (ollo:ing reuirements)

    -ensiti2ity and speciIcity ig sensiti2e)Being able to detect presence or absence o(

    substance metabolite types o( drugs in urine

    -PE&F& ,ools D reagents are able to identi(y te type o(

    drug tat is in te urine= ,e metod meets tet:o conditions are)

    E&. $en7yme immunoassay' and &munoromatograIMoreo2er bot metods a2e a common simple

    tecniue (or screening

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     ,e ad2antage o( using imunoromatograItecniues)Easy to doFast results $3>10 minutes'

    -peciIc $standards 9ational &nstitute o( "rug.buse 9&".+ no: -.MJ-.'-ensiti2ity up to 66=U

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    $ase-aturation competition &gG anti>drug

    containing en7yme substrate $antibodies':it en7yme drug in urine samples to be

    screened $antigen' ,is test is a ualitati2e

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    ;esult@rine sample $V'-aturation occurs+ meaning tat &g G anti>

    drug containing en7ymes can not bind to te

    en7yme o( te drugs e#amined=9o color cange=

    @rine sample $>'-aturation does not occur+ it means &g G anti>

    drug containing en7yme could bind to (ull orpart by en7ymes o( te drug :ere e#amined=

    &t canges color=

    -ingle "etection o( "rugs and

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    g gMetabolites

    *nly detect one type o( drug ,E-, -,;&P D -,&K .llo: samples and reagents at room

    temperature=

    ;eagents opened sortly be(ore done"ip tesstrip into te urine sample= "o not

    e#ceed te ma#imum limit sign on te strip;ead te results o( te Irst 3>5 minutes and

    3>5 minutes bot

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    %est &ard ?et te samples and reagents at room

    temperature=;eagents opened sortly be(ore done

    Put 3>5 drops o( urine samples in te sample7one

    ;ead te results o( te Irst 3>5 minutes and3>5 minutes bot

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    &nterpretation o( ;esults

    'ositi"eForming a pin line on te 7one + so:ed drug

    le2els abo2e te tresold 2alue

    (egati"e  ,ere are t:o pin lines on 7one , $test' 7one

    and $control'

    &t could mean)

    9o drug substances in te urine?e2els belo: te tresold $cut o point' tat can

    be detected by te test tool i( dubious conIrmation

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    &n2estigations

    >ray,>scan

    EKG

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    omplication

    &n(ection J&A+ epatitis+ and tuberculosis ,racs+W 2isible puncture scars+ are caused

    by repeated in

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    Prognosis

    0U e#posure to to#ins can be treated andremo2ed

    10U admitted to &@

    9on to#ic e#posure or ligt can o(ten be

    sent omePsyciatric consultation i( tere is an

    attempt to commit suicide

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    ""

    )pioidJypoglycemia

    Jypo#ia

    &ntracerebral

    emorrage.lcool into#ication

    Jepaticencepalopaty

    JypotermiaJyponatremia

    sei7ures

    $arbiturat

    .lcool into#ication

    Ben7odia7epin into#ication

    -epsis

    sei7ures

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    ""

    $en*odia*epins.lcool into#ication

    Barbituratinto#ication

    JypoglycemiaMeningitis

    -epsis

    Halusinogen

    "elirium

    -i7o(ren Jead in