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Frudensia Kristiana
405110031
Group 10
Problem 5“Emergency Medicine Bloc!
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"iagnosis Multia#ial$PP"% &&&'
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"a(tar Kategori "iagnosisF0 ) Gangguan Mental *rgani+ ,ermasu Gangguan Mental
-imtomati
F1 ) Gangguan Mental dan Perilau .ibat Penggunaan /at Psioati( F10 ) Gangguan mental dan perilau aibat penggunaan aloolF11 ) Gangguan mental dan perilau aibat penggunaan opioidaF1 ) Gangguan mental dan perilau aibat penggunaan anabinoida
F13 ) Gangguan mental dan perilau aibat penggunaan sedati2a atauipnotiaF14 ) Gangguan mental dan perilau aibat penggunaan oainF15 ) Gangguan mental dan perilau aibat penggunaan stimulansia lain
termasu a(einF1 ) Gangguan mental dan perilau aibat penggunaan alusinogenia
F1 ) Gangguan mental dan perilau aibat penggunaan tembaauF1 ) Gangguan mental dan perilau aibat penggunaan pelarut yang
muda menguapF16 ) Gangguan mental dan perilau aibat penggunaan 7at multipel
dan penggunaan 7at psioati( lainnya
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F ) -i7o(renia+ Gangguan -i7otipal dan Gangguan8aam
F3 ) Gangguan -uasana Perasaan
F4 ) Gangguan 9euroti+ Gangguan -omato(orm danGangguan yang beraitan dengan -tres
F5 ) -indrom Perilau yang Berubungan denganGangguan Fisiologis dan Fator Fisi
F ) Gangguan Kepribadian dan Perilau Masa "e:asa
F ) ;etardasi Mental
F ) Gangguan Perembangan PsiologisF6 ) Gangguan Perilau dan Emosional dengan *nset
Biasanya pada Masa Kana dan ;ema
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"iagnosis Multiasial
• ,u
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.#is &Gangguan Klinis $F00>06+ F10>6+ F0>6+ F30>36+ F40>
4+ F50>56+ F>+ F0>6+ F60>6+ F66'Kondisi ?ain yang Men6'$tida ada diagnosis /03=+ diagnosis tertunda ;4='
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.#is &&&Kondisi Medi @mum
.#is &A
Masala Psiososial dan ?ingungan$eluarga+ lingungan social+ pendidian+peer
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.#is A
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.#is A Penilaian Fungsi -ecara Global $Global .ssesment o( Functioning G.F -cale' 100>61 ge1 ge1 ge1 bbrp ge51 ge41 ge31 bbrp disabilitas dlm ubungan dgn realita C omuniasi+ disabilitasberat dlm beberapa (ungsi
30>1 disabilitas berat dlm omuniasi C daya nilai+ td mampu ber(ungsi
dlm ampir semua bidang 0>11 baaya mencederai diriDorang lain+ disabilitas sangat berat dlm
omuniasi C mengurus diri
10>01 persisten dan lebi serius
0 in(ormasi tida adeuat
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"rug abuse
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ommon "rugs o( .buse
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*pioid
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*pioid Eect
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ttp)DD:::=ncbi=nlm=ni=go2Dboosel(Dpicrender=(cgiHboossamsatipCpart.4566Cblobnametip54aIg=
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Jallucionogen
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annabis
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Jo: to @seH
-moed euporic eects in minutes+Pea ) 30 minutes+?asts ) >4 ours+
Motor C cogniti2e eect ) 5>1 ours
*rally bro:nies+ caes= >3 times dose toacie2e same eect as smoed=
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.mpetamine
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"-M &A>,; ;&,E;&. F*;.MPJE,.M&9E &9,*&.,&*9
Kaplan and -adocLs -ynopsis o(
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"-M &A>,; ;&,E;&. F*;.MPJE,.M&9E 8&,J";.8.?
Kaplan and -adocLs -ynopsis o(
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Jypnotics+ -edati2es+.n#iolytics
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&nto#ication and 8itdra:al
Kaplan and -adocLs Pocet Jandboo o( linical
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,reatment o( Ben7odia7epine8itdra:al
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.lcool
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"-M>&A>,; "iagnostic riteria (or.lcool 8itdra:al
.= essation o( $or reduction in' alcool use tat as been ea2yand prolonged
B= ,:o $or more' o( te (ollo:ing+ de2eloping :itin se2eralours to a (e: days a(ter riterion .)
1= autonomic yperacti2ity $e=g=+ s:eating or pulse rategreater tan 100'
= increased and tremor 3= insomnia 4= nauseaD2omiting 5= transient 2isual+ tactile+ or auditory allucinations or
illusions = psycomotor agitation
= an#iety = grand mal sei7ures
= ,e symptoms in riterion B cause clinically signiIcantdistress or impairment in social+ occupational+ or oterimportant areas o( (unctioning
"= ,e symptoms are not due to a general medical condition andare not better accounted (or by anoter mental disorder
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9icotine
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aeine
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Withdrawal Symptoms Intoxications
Headache $o(ten described asbeing gradual in de2elopment
and diuse+ and sometimestrobbing and se2ere'Fatigue >> $e=g=+ (atigue+tiredness+ letargy+ sluggisness'Sleepiness/drowsiness >> $e=g=+sleepy+ dro:sy+ ya:ning'
Difculty concentrating >>$e=g=+ mu77y'Work difculty >> $e=g=+decreased moti2ation (ortassD:or'Irritability >> $e=g=+ irritable+
cross+ miserable+ decreased :ell>beingDcontentedness'Depression >> $e=g=+ depressedmood'Anxiety >> $e=g=+ an#ious+ner2ous'
Flulike symptoms >> $e=g=+nauseaD2omiting+ muscle
ner2ousness $an#iety'+restlessness+
e#citement+insomnia+rambling No: o( tougt andspeec+gastrointestinal upsetremors+
tacycardia+diuresis+muscle t:itcing+periods o( ine#austibility+ andpsycomotor agitation=
&n addition+ tere a2e beenreports o( patients :it caeineinto#ication a2ing (e2er+irritability+ tremors+ sensorydisturbances+ tacypnea+ andeadaces= Jig dose caeine
to#icity is 2ery rarely (atal=Jo:e2er+ caeine can be letal at
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Psyciatry Emergency
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"-M > &A
;ecent ingestionBea2ior canges $e=g= aggression'
-lurred speec
oordination
@nsteady gait
9ystagmus
O .ttention or memory
-tupor or coma
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-upport Aital -igns
Measure 2ital signs (reuently.ddress li(e>treatening problems .Bs
*( Emergency are
9o medication until are sure tey are
needed
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.ir:ay and Breating
.ssure adeuate 2entilation-traigten ead $i( no nec in
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irculation
Maintain adeuate blood pressure-tart &A line@se large>gauge needle
@se a slo: drip until no: i( need Nuids
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-peciIc "rugs ) .ntidotes
*pioids R nalo#oneMonitor possible opioid abstinence syndrome
B"/ R Numa7enilMonitor possible sei7ures C S intracran press
.tropine>lie drugsR pysostigmine
Barbiturates R 9o antidoteForced diuresis C alalini7ation o( urine
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GE*ME,;&.? J.?@&9.,&*9
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Brain &n2ol2ement
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Jeroin
Jeroin enters te brain+ con2erted tomorpine+ binds to opioid receptors$located in brain+ body+brainstem' aectsperception o( pain+ and alter breating+ BP+
J;+ arousal+ etc;egular eroin use tolerancedecreased pysiological andpsycological eect o( drug more eroin
needed to reac te same intensity o(eect
9ational &nstitute on "rug .bu
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9ational &nstitute on "rug .bu
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Mari
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?-"
"isrupting interaction o( ner2e cells andneurotransmitter serotonin impairscontrol o( bea2ioral+ perceptual+ andregulatory systems+ including mood+
unger+ body temperature+ se#ualbea2ior+ muscle control+ and sensoryperception
&mpairs glutamate receptors impairs
perception o( pain+ responses to teen2ironment+ and learning and memory=
9ational &nstitute on "rug .bu
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.mpetamine
Binds to serotonin transporter
prolongedserotonin signal
Enters serotonergic neurons releasemore serotonin
-erotonin is a neurotransmitter tat playsan important role in te regulation o( mood+sleep+ pain+ appetite+ and oter bea2iors=
9ational &nstitute on "rug .bu
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Metampetamine
&ncreases te release and bloc tereuptae o( dopamine euporia
ronic abuse reduced motor sills andimpaired 2erbal learning+ se2ere structural
and (unctional canges in areas o( tebrain associated :it emotion and memory cogniti2e and emotional problems
9ational &nstitute on "rug .bu
-edati2es+ Jypnotics+
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-edati2es+ Jypnotics+.n#iolytics
Binds to G.B.. receptors
increaseaTnity to G.B. increase te No: o(cloride ions torug te cannel into teneuron
G.B. stimulation results less cloride inNutan :as caused by G.B. stimulationbe(ore ben7odia7epine administrations tolerance and dependence
Kaplan and -adocLs -ynopsis o(
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Ecstasy
Binds to serotonin transporter
prolongedserotonin signal
Enters serotonergic neurons releasemore serotonin
?esser eect in dopamine.(ter drugs use ) con(usion+ depression+
sleep problems+ drug cra2ing+ and se2erean#iety
ronic ) impairs cogniti2e ability
9ational &nstitute on "rug .bu
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.lcool
9o single molecular targetsEects on membranes o( neurons-ort term ) increasing Nuidity o( te
membranes
?ong term ) membranes become rigi
Kaplan and -adocLs -ynopsis o(
JarrisonLs Principle o( &nternal Medicine 1t Ed
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.lcoolLs .ect on te Brain
Alcoholism shrinks the brain
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"iagnosis
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Eyes8atering eyes occur during opiate :itdra:al=
Pin>point pupils suggests te recentadministration o( opiates=
"ilated pupils occurs in opiate :itdra:al+ and:ic also occur (ollo:ing te use o(ampetamine+ cocaine+ allucinogens $?-"'+ andanticolinergic drugs $in some *, drugs'=
9ystagmus is indicati2e o( into#ication :it
sedati2e ypnotics;ed eye $dilatation o( con
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Mout"ental caries is (reuently (ound in opiate
dependent users $due to poor dental ygieneand predilection (or s:eet (ood'=
?oss o( se2eral teet may occur in te courseo( con2ulsions during sedati2e ypnotic:itdra:al=Breat odour may indicate sol2ents or
alcool abuse=
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-inGooseNes $pilo>erection' indicates opiate
:itdra:al=Pro(use s:eating indicates :itdra:al (rom
sedati2e>ypnotics and alcool=-cars o( abscesses o2er any:ere o( te
body
9eedle puncture mars in te sin o2erlying
te 2eins o( in
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9euromuscular system ,remor and muscle t:itcing are signs o(
opiate :itdra:al=-e2ere :asting o( te muscle occurs :en
drug lie petidine is repeatedly in
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?aboratory E#amination
"rug test lab management include)-creening test-ee te presence D absence o( te substance D
metabolite
Kno:ing te type o( substance D metabolitecontained-etting presence D absence complications
due to drug use
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?aboratory metod (or screening drugs and ismetobolit must a2e te (ollo:ing reuirements)
-ensiti2ity and speciIcity ig sensiti2e)Being able to detect presence or absence o(
substance metabolite types o( drugs in urine
-PE&F& ,ools D reagents are able to identi(y te type o(
drug tat is in te urine= ,e metod meets tet:o conditions are)
E&. $en7yme immunoassay' and &munoromatograIMoreo2er bot metods a2e a common simple
tecniue (or screening
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,e ad2antage o( using imunoromatograItecniues)Easy to doFast results $3>10 minutes'
-peciIc $standards 9ational &nstitute o( "rug.buse 9&".+ no: -.MJ-.'-ensiti2ity up to 66=U
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$ase-aturation competition &gG anti>drug
containing en7yme substrate $antibodies':it en7yme drug in urine samples to be
screened $antigen' ,is test is a ualitati2e
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;esult@rine sample $V'-aturation occurs+ meaning tat &g G anti>
drug containing en7ymes can not bind to te
en7yme o( te drugs e#amined=9o color cange=
@rine sample $>'-aturation does not occur+ it means &g G anti>
drug containing en7yme could bind to (ull orpart by en7ymes o( te drug :ere e#amined=
&t canges color=
-ingle "etection o( "rugs and
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g gMetabolites
*nly detect one type o( drug ,E-, -,;&P D -,&K .llo: samples and reagents at room
temperature=
;eagents opened sortly be(ore done"ip tesstrip into te urine sample= "o not
e#ceed te ma#imum limit sign on te strip;ead te results o( te Irst 3>5 minutes and
3>5 minutes bot
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%est &ard ?et te samples and reagents at room
temperature=;eagents opened sortly be(ore done
Put 3>5 drops o( urine samples in te sample7one
;ead te results o( te Irst 3>5 minutes and3>5 minutes bot
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&nterpretation o( ;esults
'ositi"eForming a pin line on te 7one + so:ed drug
le2els abo2e te tresold 2alue
(egati"e ,ere are t:o pin lines on 7one , $test' 7one
and $control'
&t could mean)
9o drug substances in te urine?e2els belo: te tresold $cut o point' tat can
be detected by te test tool i( dubious conIrmation
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&n2estigations
>ray,>scan
EKG
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omplication
&n(ection J&A+ epatitis+ and tuberculosis ,racs+W 2isible puncture scars+ are caused
by repeated in
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Prognosis
0U e#posure to to#ins can be treated andremo2ed
10U admitted to &@
9on to#ic e#posure or ligt can o(ten be
sent omePsyciatric consultation i( tere is an
attempt to commit suicide
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""
)pioidJypoglycemia
Jypo#ia
&ntracerebral
emorrage.lcool into#ication
Jepaticencepalopaty
JypotermiaJyponatremia
sei7ures
$arbiturat
.lcool into#ication
Ben7odia7epin into#ication
-epsis
sei7ures
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""
$en*odia*epins.lcool into#ication
Barbituratinto#ication
JypoglycemiaMeningitis
-epsis
Halusinogen
"elirium
-i7o(ren Jead in