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Frontline Scientific Research ProjectsAdvanced in JAPAN
Frontline Scientific Research Projects Advanced in JAPAN
Newly Selected Large-scale Research Projects under FY2015Grant-in-Aid for Scientific Research
December, 2015
Ministry of Education, Culture, Sports, Science & Technology (MEXT)Japan Society for the Promotion of Science (JSPS)
Newly Selected Large-scale Research Projects under FY2015
Grant-in-Aid for Scientific ResearchM
inistry of Education, Culture, Sports, Science & Technology (MEXT)
Japan Society for the Promotion of Science (JSPS)
December, 2015
Foreword Grants-in-Aid for Scientific Research (Kakenhi ) are competitive funds disbursed for the purpose of making leapfrog advances in scientific research carried out based on the free ideas of researchers themselves—research in all fields of the humanities, social sciences and natural sciences, spanning the spectrum from basic to applied science. Grants-in-Aid are awarded through a peer-review selection process, and they support pioneering, cutting-edge research that provides the underpinnings for building a bountiful society. Within the program, various grant categories are established to coincide with the objective, content and scale of research projects. Applications are solicited and screened under the terms of each of category. This booklet introduces research projects newly selected in FY 2015, namely under the categories Specially Promoted Research and Scientific Research (S), carried out by a single researcher or a relatively small number of researchers, and Scientific Research on Innovative Areas (Research in a proposed research area), carried out by multiple researches or a research group. We will be pleased if the information provided this booklet is helpful in understanding the research activities being carried out in Japanese universities and other research institutions.
Research Promotion Bureau, Ministry of Education, Culture, Sports, Science & Technology（MEXT） (http://www.mext.go.jp/a_menu/shinkou/hojyo/main5_a5.htm)
Japan Society for the Promotion of Science（JSPS） (http://www.jsps.go.jp/english/index.html)
i
Contents
(page)
１．Distribution by Research Area of the Newly Adopted Projects ・・・・・・・・・・・・・ 1
２．List of the Newly Adopted Projects ･・・・・・・・・・・・・・・・・・・・・・・・・・・ 2
３．Abstracts of the Newly Adopted Projects
【Humanities and Social Sciences】
(1) Construction of Policy-Evaluation-Oriented and Heterogeneity-Sensitive National Transfer
Accounts and their Application to Policies for Coping with Declining Fertility and Population
Aging
(Hidehiko Ichimura：The University of Tokyo, Graduate School of Economics, Professor) ・・ 4
【Science and Engineering】
(1) Extended Telescope Array Experiment - Nearby Extreme Universe Elucidated by Highest-
energy Cosmic Rays
(Hiroyuki Sagawa：The University of Tokyo, Institute for Cosmic Ray Research, Associate Professor) ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 5
(2) Innovation of the "interstellar medium" by accurate measurements of the interstellar hydrogen
(Yasuo Fukui：Nagoya University, Graduate School of Science, Professor ) ・・・・・・・・ 6
(3) A model for formation and evolution of solid materials in space based on 3D structures of solar
primitive materials
(Akira Tsuchiyama：Kyoto University, Graduate School of Science, Professor ) ・・・・・・ 7
(4) Sub-femtosecond molecular imaging
(Kaoru Yamanouchi：The University of Tokyo, Graduate School of Science, Professor) ・・・ 8
(5) Design of light- or electromagnetic-wave-correlating phase transition materials and research
of their advanced functionalities
(Shin-ichi Ohkoshi：The University of Tokyo, Graduate School of Science, Professor) ・・・・ 9
(6) Revolutionizing organic chemistry by utilizing water as solvent
(Shu Kobayashi：The University of Tokyo, Graduate School of Science, Professor) ・・・・・ 10
(7) Spin-orbit Engineering
(Junsaku Nitta：Tohoku University, Graduate School of Engineering, Professor) ・・・・・ 11
(8) Solid-state Quantum Electrodynamics in Quantum Dot-Nanocavity Multiply-Coupled Quantum
Systems and Its Application to Novel Light Sources
(Yasuhiko Arakawa：The University of Tokyo, Institute of Industrial Science, Professor) ・・ 12
(9) Development of advanced energy storage system based on overall strategies on new materials
and new interface
(Atsuo Yamada：The University of Tokyo, Graduate School of Engineering, Professor) ・・・ 13
Grant-in-Aid for Specially Promoted Research of KAKENHI, FY2015
（Newly Adopted Projects）
- i -
ii
(10)Spin-orbitronics and device application
(Teruo Ono : Kyoto University, Institute for Chemical Research, Professor) ・・・・・・・・ 14
【Biological Sciences】
(1) Promotion of osteoimmunology for understanding the new regulatory systems of vertebrate
(Hiroshi Takayanagi：The University of Tokyo, Graduate School of Medicine and Faculty of Medicine, Professor) ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 15
(2) Comprehensive analysis of innate immunity
(Shizuo Akira：Osaka University, Immunology Frontier Research Center, Professor) ・・・ 16
(3) Elucidation of the integrated cellular network for mitochondrial biogenesis
(Toshiya Endo：Kyoto Sangyo University, Faculty of Life Sciences, Professor) ・・・・・・・ 17
（Appendix）List of the Continuing Projects for Grant-in-Aid for
Specially Promoted Research of KAKENHI ・・・・・・・・・・・・・・・・・・・・ 18
１．Distribution by Research Area of the Newly Adopted Projects ・・・・・・・・・・・・・ 23
２．List of the Newly Adopted Projects ・・・・・・・・・・・・・・・・・・・・・・・・・・ 24
３．Abstracts of the Newly Adopted Projects
【Humanities and Social Sciences】
(1) Rice Farming and Chinese Civilization : Renovation of Integrated Studies of Rice-based
Civilizations
（Shinichi Nakamura：Kanazawa University, Faculty of Letters, Professor） ・・・・・・・ 26
【Science and Engineering】
(1) Frontiers of materials science spun from topology
（Norio Kawakami：Kyoto University, Graduate School of Science, Professor） ・・・・・・ 27
(2) Precise Formation of a Catalyst Having a Specified Field for Use in Extremely Difficult Substrate
Conversion Reactions
（Kazushi Mashima：Osaka University, Graduate School of Engineering Science, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 28
(3) Science of Hybrid Quantum Systems
（Yoshiro Hirayama：Tohoku University, Graduate School of Science, Professor） ・・・・・ 29
(4) J-Physics: Physics of conductive multipole systems
（Hisatomo Harima：Kobe University, Graduate School of Science, Professor） ・・・・・・ 30
(5) Why does the Universe accelerate? -Exhaustive study and challenge for the future-
（Hitoshi Murayama：The University of Tokyo, Kavli Institute for the Physics and Mathematics of the Universe, Project Professor） ・・・・・・・・・・・・・・・・・・・ 31
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a
proposed research area) of KAKENHI, FY2015（Newly Adopted Projects）
- ii -
iii
(6) Interaction and Coevolution of the Core and Mantle: Toward Integrated Deep Earth Science
（Taku Tsuchiya：Ehime University, Geodynamics Research Center, Professor） ・・・・・・ 32
(7) Middle Molecular Strategy: Creation of Higher Bio-functional Molecules by Integrated Synthesis
（Koichi Fukase：Osaka University, Graduate School of Science, Professor） ・・・・・・・ 33
(8) Solar-Terrestrial Environment Prediction as Science and Social Infrastructure
（Kanya Kusano：Nagoya University, Solar-Terrestrial Environment Laboratory, Professor） ・・・・・・・・・・・・・・・・・・・ ・・・・・・・・・・・・・・・・・ 34
【Biological Sciences】
(1) Quality of lipids in biological systems
（Makoto Arita：RIKEN, Center for Integrative Medical Sciences, Team Leader） ・・・・・ 35
(2) Integrative understanding of biological phenomena with temperature as a key theme
（Makoto Tominaga：National Institutes of Natural Sciences, Okazaki Institute for Integrative Bioscience, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・ 36
(3) Chromosome Orchestration System
（Katsuhiko Shirahige：The University of Tokyo, Institute of Molecular and Cellular Biosciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 37
(4) Resonance Biology for Innovative Bioimaging
（Atsushi Miyawaki：RIKEN, Brain Science Institute, Laboratory Head） ・・・・・・・・ 38
(5) Discovery of the logic that establishes the 3D structure of organisms
（Shigeru Kondo：Osaka University, Graduate School of Frontier Biosciences, Professor） ・・ 39
(6) Integrative system of autonomous environmental signal recognition and memorization for plant
plasticity
（Toshinori Kinoshita：Nagoya University, Institute of Transformative Bio-Molecules, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 40
【Interdisciplinary Area】
(1) Conquering Cancer through Neo-dimensional Systems Understanding
（Satoru Miyano：The University of Tokyo, The Institute of Medical Science, Professor） ・・ 41
(2) Ocean Mixing Processes: Impact on Biogeochemistry, Climate and Ecosystem
（Ichiro Yasuda：The University of Tokyo, Atmosphere and Ocean Research Institute, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 42
(3) Non-linear Neuro-oscillology: Towards Integrative Understanding of Human Nature
（Atsushi Nambu：National Institute for Physiological Sciences, Division of System Neurophysiology, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 43
(4) "LIVING IN SPACE" - Integral Understanding of life-regulation mechanism from "SPACE"
（Satoshi Furukawa：Japan Aerospace Exploration Agency, Head of Space Biomedical Research Group, Astronaut） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 44
- iii -
iv
(5) Understanding human recognition of material properties for innovation in SHITSUKAN science
and technology
（Shin'ya Nishida：Nippon Telegraph and Telephone Corp, Human Information Science Lab, NTT Communication Science Laboratories, Senior Distinguished Scientist） ・・・・ 45
（Appendix） List of the Continuing Projects for Grant-in-Aid for Scientific
Research on Innovative Areas (Research in a proposed research area)
of KAKENHI ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 46
１．Distribution by Research Area of the Newly Adopted Projects ・・・・・・・・・・・・・ 51
２．List of the Newly Adopted Projects ・・・・・・・・・・・・・・・・・・・・・・・・・・ 52
３．Abstracts of the Newly Adopted Projects
【Integrated Disciplines】
（Informatics）
(1) Refinement and Extension of Higher-Order Model Checking
（Naoki Kobayashi：The University of Tokyo, Graduate School of Information Science and Technology, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 60
(2) Establishing Theoretical Foundations for Mathematical Modeling of Pathological Biosystems and
its Applications to Personalized Medicine
（Kazuyuki Aihara：The University of Tokyo, Institute of Industrial Science, Professor） ・・ 61
(3) Research on Information Infrastructure Platform for Sustainable Smart Mobility
（Akira Fukuda：Kyushu University, Graduate School of Information Science and Electrical Engineering, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・ 62
(4) Wild Cognitive Science：Comparative Cognitive Approach toward Understanding Evolution and
Diversity of Mind
（Masaki Tomonaga：Kyoto University, Primate Research Institute, Associate Professor） ・・ 63
(5) Neural Basis of Mental Images
（Yukiyasu Kamitani：Kyoto University, Graduate School of Informatics, Professor） ・・・ 64
(6) Research on Core Algorithms for Discrete Structure Manipulation Systems
（Shin-ichi Minato：Hokkaido University, Graduate School of Information Science and Technology, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 65
（Environmental Science）
(1) Plankton in Polar Regions toward an Understanding of their Characteristics
（Naomi Harada：Japan Agency for Marine-Earth Science and Technology, Research & Development Center for Global Change, Deputy Director of R&D Center） ・・・・・・・・ 66
Grant-in-Aid for Scientific Research (S) of KAKENHI, FY2015
（Newly Adopted Projects）
- iv -
v
(2) Mechanism of Genome Integrity Maintenance in Tissue Stem Cell
（Takeshi Todo：Osaka University, Graduate School of Medicine, Professor） ・・・・・・・ 67
(3) Molecular Mechanism for Toxic Effect of Methylmercury
（Akira Naganuma：Tohoku University, Graduate School of Pharmaceutical Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 68
(4) Physical Photochemical Functionalization of Oxide Nanotubes through Hierarchical Structure
Tuning
（Tohru Sekino：Osaka University, The Institute of Scientific and Industrial Research, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 69
（Complex Systems）
(1) Design for Driving Automation and Legal Systems Conforming to Characteristic Features and
Limitations of Cognition and/or Decision Making of Human Drivers
（Toshiyuki Inagaki：University of Tsukuba, Faculty of Engineering, Information and Systems, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 70
(2) Urgency Evaluation of the Nankai Great Earthquake and Tsunami by Scientific Ocean Drilling
（Gaku Kimura：The University of Tokyo, Graduate School of Science, Professor） ・・・・・ 71
(3) Toward Mitigating Tsunami Hazards from Outer-rise Earthquakes: Mapping Potential Earthquake
Faults and Constructing a Tsunami Database
（Shuichi Kodaira：Japan Agency for Marine-Earth Science and Technology, R&D Center for Earthquake and Tsunami, Director） ・・・・・・・・・・・・・・・・・・・・・・・ 72
(4) Evaluation and Control of Epilepsy Dynamics Based on Multimodal Brain Signals and Thermal
Neuromodulation Using Focal Brain Cooling
（Michiyasu Suzuki：Yamaguchi University, Graduate School of Medicine, Professor） ・・・ 73
(5) Toward New Frontiers in High-Resolution 3D Color Radiology Imaging
（Jun Kataoka：Waseda University, Faculty of Science and Engineering, Professor） ・・・・ 74
(6) Therapeutic Drug Discovery and Elucidation of RNA Disease Pathogenesis by Use of
CRISPR-Based Disease iPS Cells and Animal Models
（Masatoshi Hagiwara：Kyoto University, Graduate School of Medicine, Professor） ・・・・ 75
(7) Cellular Programming Using Synthetic RNP Nanosystems
（Hirohide Saito：Kyoto University, Center for iPS Cell Research and Application, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 76
(8) Development of Fluorescent Probes with Molecular Evolution Engineering
（Junichi Nakai：Saitama University, Graduate School of Science and Engineering, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 77
(9) Neuroendocrinology of Social Behavior
（Sonoko Ogawa：University of Tsukuba, Faculty of Human Sciences, Professor） ・・・・・ 78
- v -
vi
【Humanities and Social Sciences】
（Humanities）
(1) Construction of a New Knowledge Base for Buddhist Studies: Presentation of an Advanced
Model for the Next Generation of Humanities Research
（Masahiro Shimoda：The University of Tokyo, Graduate School of Humanities and Sociology, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 79
（Social Sciences）
(1) Employment Sustainability and the Shifting Paradigm of Labor Law
（Hajime Wada：Nagoya University, Graduate School of Law, Professor） ・・・・・・・・・ 80 (2) An Analytical and Practical Approach to Universal and International Access to Policy Information
（Mikitaka Masuyama：National Graduate Institute for Policy Studies, School of Policy Studies, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 81
(3) Behavioral-Economic Analysis of Long-Run Stagnation
（Yoshiyasu Ono：Osaka University, Institute of Social and Economic Research, Professor） ・ 82
(4) Risk Management of Comprehensive Monetary/Fiscal Policy: Theory, Empirics, and Simulations
（Takashi Kamihigashi：Kobe University, Research Institute for Economics and Business Administration, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 83
(5) Mutual Construction of Neuro-Psychological and Socio-Institutional Foundations of Prosocial
Behavior
（Toshio Yamagishi：Hitotsubashi University, Graduate School of International Corporate Strategy, Adjunct Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 84
【Science and Engineering】
（Interdisciplinary Science and Engineering）
(1) Nucleation
（Yuki Kimura：Hokkaido University, Institute of Low Temperature Science, Associate Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 85
(2) Achievement of Tailor-made Lighting Sources by the Control of Nanoscopic Carrier Localization
in Nitride Semiconductors
（Yoichi Kawakami：Kyoto University, Graduate School of Engineering, Professor） ・・・・ 86
(3) Research on Unexplored Frequency Quantum-Cascade Lasers Using Nitride Semiconductors
（Hideki Hirayama：RIKEN, Quantum Optodevice Laboratory, Chief Scientist） ・・・・・ 87
(4) Nanoscale Probing Photoinduced Dynamics by Optical Pump-Probe Scanning Tunneling
Microscopy
（Hidemi Shigekawa：University of Tsukuba, Faculty of Pure and Applied Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 88
(5) Novel Photonic Integration Platform with Hybrid Nanophotonics-Nanomaterials Systems
（Masaya Notomi：Nippon Telegraph and Telephone Corporation, NTT Basic Research Labs., Director of Nanophotonics Center） ・・・・・・・・・・・・・・・・・・・・・・ 89
- vi -
vii
(6) Quantum Theoretical Analyses of Plasma Processing for Novel and Diverse Materials Using
Multi-Scale Numerical Simulations
（Satoshi Hamaguchi：Osaka University, Graduate School of Engineering, Professor） ・・・ 90
(7) Cell Dynamics Studied by X-Ray Laser Diffraction
（Yoshinori Nishino：Hokkaido University, Research Institute for Electronic Science, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 91
（Mathematical and Physical Sciences）
(1) Lattices, Automorphic Forms and Moduli Spaces
（Shigeyuki Kondo：Nagoya University, Graduate School of Mathematics, Professor） ・・・ 92
(2) Geometric Group Theory
（Koji Fujiwara：Kyoto University, Graduate School of Science, Professor） ・・・・・・・・ 93
(3) Renovating Solutions and Applications of Coefficient Inverse Problems for Partial Differential
Equations
（Masahiro Yamamoto：The University of Tokyo, Graduate School of Mathematical Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 94
(4) Study of the Ultra High Energy Cosmic Ray Source Evolution by Detailed Measurement of Cosmic
Rays in the Wide Energy Range
（Shoichi Ogio：Osaka City University, Graduate School of Science, Professor） ・・・・・・ 95
(5) Sensitive Search for New Physics Law with Precision Measurement of Muon Anomalous Magnetic
Moment
（Naohito Saito：High Energy Accelerator Research Organization, Institute of Particle and Nuclear Studies, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・ 96
(6) Investigation of Inflation Cosmology with Ground-based Experiment of Large-angle Distribution
of CMB B-mode Polarization
（Chiko Otani：RIKEN, Center for Advanced Photonics, Team Leader） ・・・・・・・・・・ 97
(7) Probing into the Intra-Halo Light and the Epoch of Cosmic Re-Ionization by Rocket Experiments
to Measure the Cosmic Infrared Background
（Shuji Matsuura：Kwansei Gakuin University, School of Science and Technology, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 98
(8) Understanding of the Superconducting Mechanism and Search for a Novel Superconducting
State in Uranium Heavy-Fermion Compounds
（Kenji Ishida：Kyoto University, Graduate School of Science, Professor） ・・・・・・・・・ 99
(9) Macroscopic Theory for Robustness and Plasticity in Cells
（Kunihiko Kaneko：The University of Tokyo, Graduate School of Arts and Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 100
(10)The Quest for the Ultimate Production Mechanism of Pulsating Auroras with Extremely High Time
Resolution and Coordinated Observations from Space and Ground
（Ryoichi Fujii：Nagoya University, Solar-Terrestrial Environment Laboratory, Professor） ・・ 101
- vii -
viii
(11)Creation of the Best Model of the Earth’s Core
（Eiji Ohtani：Tohoku University, Graduate School of Science, Professor） ・・・・・・・・ 102
(12)Advanced Trace Organic Compound Study in Planetary Materials: Development of High
Sensitivity and High Resolution
（Hiroshi Naraoka：Kyushu University, Faculty of Science, Professor） ・・・・・・・・・・ 103
(13)2D Imaging Study of High Power Heating / Acceleration of High Magnetic Field Reconnection for
its Physics and Application
（Yasushi Ono：The University of Tokyo, Graduate School of Frontier Science, Professor） ・・・ 104
(14 )Proof of Fast Ignition Scheme Using Super-penetration of Laser Light
（Kazuo A. Tanaka：Osaka University, Graduate School of Engineering, Professor） ・・・・ 105
（Chemistry）
(1) Nonadiabatic Electron Dynamics in Chemistry of Charge Separation, Proton Transfer, Electron
Transmission, and Huge Electronic-State Fluctuation
（Kazuo Takatsuka：The University of Tokyo, Graduate School of Arts and Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 106
(2) Ultrafast Photoelectron Spectroscopy of Solution Chemistry
（Toshinori Suzuki：Kyoto University, Graduate School of Science, Professor） ・・・・・・ 107
(3) Hierarchal Control of Carbon Cluster Organization and their Function
（Eiichi Nakamura：The University of Tokyo, Graduate School of Science, Professor） ・・・ 108
(4) Development of High Performance Acid Base Combined Nanocatalysts
（Kazuaki Ishihara：Nagoya University, Graduate School of Engineering, Professor） ・・・ 109
(5) Development of Molecular Transformations by Means of Light and Metals Directing towards
Straightforward Synthesis
（Masahiro Murakami：Kyoto University, Graduate School of Engineering, Professor）・・・ 110
(6) Creation of Superatoms Based on the Precision Inorganic Synthesis and Elucidation of its
Function
（Kimihisa Yamamoto：Tokyo Institute of Technology, Chemical Resources Laboratory, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 111
(7) Role of Liquid for Controlling Autonomy of Soft Materials Containing Ionic Liquids
（Masayoshi Watanabe：Yokohama National University, Graduate School of Engineering, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 112
（Engineering）
(1) Frontier of Precision Optical Metrology Created by the Ultra-Precision Optical Nano-Grid
Reference Artifact and the Absolute Optical Scale Comb
（Wei Gao：Tohoku University, Graduate School of Engineering, Professor） ・・・・・・・ 113
- viii -
ix
(2) Construction of Functionalized Carbon Nano-Materials and Development of Innovative Energy
Devices
（Shigeo Maruyama：The University of Tokyo, Graduate School of Engineering, Professor） ・・ 114
(3) Cell Exercise toward Elastic Cellular Tissue
（Makoto Kaneko：Osaka University, Graduate School of Engineering, Professor） ・・・・ 115
(4) Formation of Self-Aligned Super-Atom-Like Si-Ge Based Quantum Dots and Characterization
of their Optical and Electrical Properties
（Seiichi Miyazaki：Nagoya University, Graduate School of Engineering, Professor） ・・・・ 116
(5) Creation of Ultra-low Power-consumption Semiconductor Membrane Photonic Integrated
Circuits toward On-chip Optical Interconnections
（Shigehisa Arai：Tokyo Institute of Technology, Graduate School of Science and Engineering, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 117
(6) Development of Advanced Biosensing Systems Utilizing Magnetic Markers and Magnetic Sensors
（Keiji Enpuku：Kyushu University, Research Institute of Superconductor Science and Systems, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 118
(7) Integrated Research on State-of-the-art Multi-sensors In-situ Observation of Storm Genesis
and Reduction of Serious Disaster due to Heavy Rainfall
（Eiichi Nakakita：Kyoto University, Disaster Prevention Research Institute, Professor） ・・・ 119
(8) Ferrous Structural Superelastic Alloys - New Stage of Shape Memory Materials -
（Ryosuke Kainuma：Tohoku University, Graduate School of Engineering, Professor） ・・・ 120
(9) Novel Material Design Based on Unified Understanding on Unique Mechanical Behaviors in Bulk
Nanostructured Metals
（Nobuhiro Tsuji：Kyoto University, Graduate School of Engineering, Professor） ・・・・・ 121
(10)Systematization of Academic Foundation on Grain Refinement Strengthening in Steel
（Setsuo Takaki：Kyushu University, Graduate School of Engineering, Professor） ・・・・・ 122
(11)Development of Digital Bio-Molecular Device and Biomedical Applications
（Eiichi Tamiya：Osaka University, Graduate School of Engineering, Professor） ・・・・・ 123
(12)Discharge Induced in a High-Energy Electromagnetic Beam and its Engineering Applications
（Kimiya Komurasaki：The University of Tokyo, Graduate School of Engineering, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 124
(13)New Developments in Science and Engineering of Mineral Resources from Present and Past
Oceans
（Yasuhiro Kato：The University of Tokyo, Graduate School of Engineering, Professor） ・・ 125
【Biological Sciences】
（Biological Sciences）
(1) How are Synapses Formed, Fine-tuned and Eliminated in vivo? Novel Mechanisms by the
Complement Family Proteins
（Michisuke Yuzaki：Keio University, School of Medicine, Professor） ・・・・・・・・・・・ 126
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x
(2) Elucidation of Mechanisms Regulating Neural Stem/Progenitor Cell Fate
（Yukiko Gotoh：The University of Tokyo, Graduate School of Pharmaceutical Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 127
(3) Transcriptional Regulation by TGF-β Signaling and its Relation to Progression of Cancer
（Kohei Miyazono：The University of Tokyo, Graduate School of Medicine, Professor） ・・・ 128
（Biology）
(1) Studies in Structural Physiology of Channels
（Yoshinori Fujiyoshi：Nagoya University, Graduate School of Pharmaceutical Sciences/CeSPI, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 129
(2) Endomembrane-Mediated Organ Straightening and Defense in Plants
（Ikuko Hara-Nishimura：Kyoto University, Graduate School of Science, Professor） ・・・・ 130
(3) Contribution of Opsin Properties to Non-Visual Functions
（Akihisa Terakita：Osaka City University, Graduate School of Science, Professor） ・・・・ 131
(4) Molecular Mechanisms of Color Pattern Formation in Mimicry Controlled by Supergene
（Haruhiko Fujiwara：The University of Tokyo, Graduate School of Frontier Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 132
（Agricultural Sciences）
(1) Towards Understanding Molecular Interactions of Rice and the Blast Fungus Magnaporthe
Oryzae
（Ryohei Terauchi：Iwate Biotechnology Research Center, Department of Genomics and Breeding, Head） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 133
(2) Molecular Basis of Infection Strategy in Plant Pathogenic Fungi: Host Recognition and Infection
Structure Development
（Yasuyuki Kubo：Kyoto Prefectural University, Graduate School of Life and Environmental Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・ 134
(3) Analysis on Molecular Nutritional Functions of Bile Acids as a Feeding Signal, and Regulation of
Metabolic Response to Feeding by Food Factors
（Ryuichiro Sato：The University of Tokyo, Graduate School of Agriculture and Life Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 135
(4) Identification of Bull Pheromone and its Application to the Improvement of Fertility
（Kei-ichiro Maeda：The University of Tokyo, Graduate School of Agriculture and Life Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 136
（Medicine, Dentistry, and Pharmacy）
(1) Development of Novel Anti-Infectious Drugs Exhibiting Therapeutic Effects
（Kazuhisa Sekimizu：The University of Tokyo, Graduate School of Pharmaceutical Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 137
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(2) Regulatory Mechanism of Immunoglobulin Gene Diversification and Genome Instability by
RNA-Editing Catalyzed by Activation-Induced Cytidine Deaminase (AID)
（Tasuku Honjo：Kyoto University, Graduate School of Medicine, Guest Professor） ・・・・ 138
(3) Engulfment of Apoptotic Cells and Asymmetry of Plasma Membranes
（Shigekazu Nagata：Osaka University, Immunology Frontier Research Center, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 139
(4) Previously Unappreciated Roles for Basophils in Health and Disease
（Hajime Karasuyama：Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・ 140
(5) Elucidation of the Host’s Homeostatic Responses by the Regulation of Immune System and its
Application to the Prevention and Treatment of Immunological Disorders
（Tadatsugu Taniguchi：The University of Tokyo, Institute of Industrial Science, Project Professor） ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 141
(6) Development of a Novel Strategy for Life Style Disease through Exploration of the Roles of
Mineral- and Gluco-Corticoids in Hypertension and Organ Dysfunction
（Toshiro Fujita：The University of Tokyo, Research Center for Advanced Science and Technology, Emeritus Professor/Project Researcher） ・・・・・・・・・・・・・・・・・・ 142
(7) Development of a Novel Anti-Aging Strategy by Elucidating the Mechanisms Regulating Aging
through a Muscle Centric Organ Network
（Kohjiro Ueki：The University of Tokyo, Graduate School of Medicine, Professor） ・・・・ 143
(8) Understanding the Mechanism How the Skin Responses to External Stimuli
（Kenji Kabashima：Kyoto University, Graduate School of Medicine, Professor） ・・・・・ 144
(9) Achievement of Highly Accurate Diagnosis of Early Pancreatic Cancer in Japanese Patients
through a Comprehensive/Integrated Approach
（Masaki Mori：Osaka University, Graduate School of Medicine, Professor） ・・・・・・・ 145
(10)Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving
Cancer Stem Cells
（Yoshihiko Maehara：Kyushu University, Faculty of Medical Sciences, Professor） ・・・・ 146
（Appendix）List of the Continuing Projects for Grant-in-Aid for
Scientific Research (S) of KAKENHI ・・・・・・・・・・・・・・・・・・・・・・ 148
【Reference】
・Outline of the Grant-in-Aid for Scientific Research - KAKENHI ・・・・・・・・・・・ 169
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