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DIGITAL FRIABILITY APPARATUS by Dr AMIT S.MANE PG Dept of Rasashastra

Friability

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Page 1: Friability

DIGITAL FRIABILITY APPARATUS

by

Dr AMIT S.MANEPG Dept of Rasashastra

Page 2: Friability

Friability??

Page 3: Friability

Introduction• Standardization of tabletsDiameter sizeUniformity of weightThicknessHardnessFriabilityPercentage of medicamentRate of disintegration

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Digital friability apparatus• Digital friability test apparatus is specially

used to determine the durability of tablets from the time of production to the time use.

• Friability test is also performed to evaluate the ability of the tablets to withstand abrasion in packing, handling and transporting.

• It is also called as friabilator

Page 5: Friability

Parts of the Instrument

•Plastic chamber•Timer•Partition

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Plastic chamber

Chamber

Partition

Mounting block Tablet

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Types

SINGLE DRUM DOUBLE DRUM

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Procedure • A number of tablets weighed and

placed in tumbling chamber .• This chamber rotated for four

minutes or 100 revolutions.• During each revolution tablets fall

from a distance of six inches to undergo shock

Page 9: Friability

Cont…

• Each of two acrylic drums provided with an arm which carries the tablets along with it up to specific height and allows them to fall from specific height,while the drums are rotating.• Thus the tablet rub against each other

without hard impact.• It is fitted with digital revolution counter

showing the current revolution for test.

Page 10: Friability

Cont…

• The digital LCD screen displays various important massages regarding the test like –set rotations and actual rotations of test.

• Tablets are weighed before and after the test and the difference is weight for particular time prior indication the rate of abrasion.

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Cont…

• After 100 revolutions the tablet are again weighed and loss in weight indicates the friability.• Acceptable limits of weight loss

should not be more than 0.8%

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Salient features

• Accurate, reliable and stable.• Instrument for measuring abrasion

and strength of tablet.• Sturdy motor to drive drums at

constant speed.• Powerful, sturdy motor ensures

smooth function.

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Digital Friability Test Apparatus Model No.:IN-902

Microprocessor Friability Test Apparatus Model: IN-982

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Product Code : Model:VFT-DV

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Bellstone Tablet Friability Test Apparatus Product Code : BHI-PTM-4530

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References.

• Introduction to Pharmaceutics-I Ashok Gupta

• Pharmaceutics-I R.M.Mehta• Article - Biological Museum• Article - Magumps Medical Equipments• Article - Rimek Pharmaceutical Machinery• Internet

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Thank you….