2
FREQUENTLY ASKED QUESTIONS Q: Is the Vein Ablation procedure painful? A: Patients generally report feeling little, if any, pain during and after the procedure. Q: How quickly can I resume normal activity? A: Patients are encouraged to walk immediately following the procedure, and most patients resume normal activities within 2-4 days. Q: How soon after treatment will my symptoms improve? A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure. Most patients report minimal to no scarring, bruising, or swelling following the Vein Ablation procedure. Q: How is the Vein Ablation procedure different from vein stripping? A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Vein Ablation procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery. 1,2 Q: Is the Vein Ablation procedure covered by insurance? A: The Vein Ablation procedure is covered by most health insurances for symptomatic patients diagnosed with venous reflux. References 1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-14 2 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218 Additional Available Venous Procedures Venous Micro Phlebectomy Sclerotherapy Intravascular Ultrasound of Deep Iliac Veins Do you experience the discomfort and swelling of varicose veins? If so, you may be suffering from Chronic Venous Insufficiency. Approximately 25 million people in the United States suffer from this condition. Traditionally, patients diagnosed with venous reflux would undergo vein stripping surgery. Now, patients can be treated with the Vein Ablation procedure, a minimally invasive and more comfortable alternative to painful vein stripping surgery. Do you have VARICOSE VEINS? If yes, you may suffer from venous reflux disease. Our cardiologists are experts in the diagnosis and treatment for Chronic Venous Insufficiency. We can help you return to a more active and enjoyable lifestyle www.cava.cc EXPERT PHYSICIANS Our physicians are board certified in Cardiology and Interventional Cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, atherectomy and stenting for lower extremity peripheral arterial disease. Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries. Vascular Center of Michigan 5701 Bow Pointe Dr. Suite 210. Clarkston, MI 48346 Cardiology and Vascular Associates, P.C. 42557 Woodward, Suite 200. Bloomfield Hills, MI 48304 5701 Bow Pointe Dr. Suite 205. Clarkston, MI 48346 (248) 365-6900 Michele De Gregorio MD, FACC Abdul R. Halabi MD, FACC Kirit C. Patel MD, FACC

FREQUENTLY ASKED QUESTIONS VARICOSE VEINS … · Bloom˜eld Hills, MI 48304. If yes, you may su˜er from venous re˚ux disease. Our cardiologists are experts in the diagnosis and

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FREQUENTLY ASKED QUESTIONS

If so, you may be suffering from venous reflux

disease. Approximately 25 million people in the

United States suffer from this condition.

Traditionally, patients diagnosed with venous reflux

would undergo vein stripping surgery. Now, patients

can be treated with the Venefit™ procedure,

formerly known as the VNUS Closure™ procedure

— a minimally invasive and more comfortable

alternative to painful vein stripping surgery.

Do you experience the discomfort and swelling of varicose veins?

References

1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-14

2 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218

Nishit Choksi. MD, FACC

Our physicians are board certified in Cardiology and interventional cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, arthrectomy and stenting for lower extremity peripheral arterial vascular disease.

Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries.

www.cava.cc

Kirit C. Patel. MD, FACC

Michele De Gregorio. MD, FACC

Q: Is the Venefit™ procedure painful?

A: Patients generally report feeling little, if any, pain during

and after the procedure.

Q: How quickly can I resume normal activity?

A: Patients are encouraged to walk immediately following

the procedure, and most patients resume normal activities within 1-3 days.

Q: How soon after treatment will my symptoms improve?

A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure.

Q: Is there any scarring, bruising, or swelling after the procedure?

A: Most patients report minimal to no scarring, bruising, or swelling following the Venefit procedure.

Q: How is the Venefit procedure different from vein stripping?

A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Venefit procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery.1,2

Q: Is the Venefit procedure covered by insurance?

A: The Venefit procedure is covered by most health

insurances for patients diagnosed with venous reflux.

(248) 333-1172 x 301

Do you have VARICOSE VEINS?

Cardiology and Vascular Associates, P.C.42557 Woodward, Suite 100. Bloom�eld Hills, MI 48304

If yes, you may su�er from venous re�ux disease. Our cardiologists are

experts in the diagnosis and treatment for Venous Re�ux Disease.

Abdul R. Halabi. MD, FACC

EXPERT PHYSICIANS

THE BENEFITS FOR YOUOur physicians fellowship training and years of experience

provide them the skills and confidence to deliver outstanding results for you.    

Let CAVA help you return to a more active and enjoyable lifestyle

new CAVA_Brochure.pdf 1 6/27/12 9:47 AM

FREQUENTLY ASKED QUESTIONS

Q: Is the Vein Ablation procedure painful?A: Patients generally report feeling little, if any, pain during and after the procedure.

Q: How quickly can I resume normal activity?A: Patients are encouraged to walk immediately following the procedure, and most patients resume normal activities within 2-4 days.

Q: How soon after treatment will my symptoms improve? A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure. Most patients report minimal to no scarring, bruising, or swelling following the Vein Ablation procedure.

Q: How is the Vein Ablation procedure different from vein stripping?A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Vein Ablation procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery.1,2

Q: Is the Vein Ablation procedure covered by insurance?A: The Vein Ablation procedure is covered by most health insurances for symptomatic patients diagnosed with venous reflux.

References

1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-142 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218

Additional Available Venous Procedures Venous Micro PhlebectomySclerotherapyIntravascular Ultrasound of Deep Iliac Veins

Do you experience the discomfort and swelling of varicose veins?If so, you may be suffering from Chronic Venous

Insufficiency. Approximately 25 million people

in the United States suffer from this condition.

Traditionally, patients diagnosed with venous

reflux would undergo vein stripping surgery.

Now, patients can be treated with the Vein

Ablation procedure, a minimally invasive and

more comfortable alternative to painful vein

stripping surgery.

Do you have VARICOSE VEINS?

If yes, you may suffer from venous reflux disease. Our cardiologists

are experts in the diagnosis and treatment for

Chronic Venous Insufficiency.

We can help you return to a more active and enjoyable lifestyle

www.cava.cc

FREQUENTLY ASKED QUESTIONS

If so, you may be suffering from venous reflux

disease. Approximately 25 million people in the

United States suffer from this condition.

Traditionally, patients diagnosed with venous reflux

would undergo vein stripping surgery. Now, patients

can be treated with the Venefit™ procedure,

formerly known as the VNUS Closure™ procedure

— a minimally invasive and more comfortable

alternative to painful vein stripping surgery.

Do you experience the discomfort and swelling of varicose veins?

References

1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-14

2 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218

Nishit Choksi. MD, FACC

Our physicians are board certified in Cardiology and interventional cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, arthrectomy and stenting for lower extremity peripheral arterial vascular disease.

Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries.

www.cava.cc

Kirit C. Patel. MD, FACC

Michele De Gregorio. MD, FACC

Q: Is the Venefit™ procedure painful?

A: Patients generally report feeling little, if any, pain during

and after the procedure.

Q: How quickly can I resume normal activity?

A: Patients are encouraged to walk immediately following

the procedure, and most patients resume normal activities within 1-3 days.

Q: How soon after treatment will my symptoms improve?

A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure.

Q: Is there any scarring, bruising, or swelling after the procedure?

A: Most patients report minimal to no scarring, bruising, or swelling following the Venefit procedure.

Q: How is the Venefit procedure different from vein stripping?

A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Venefit procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery.1,2

Q: Is the Venefit procedure covered by insurance?

A: The Venefit procedure is covered by most health

insurances for patients diagnosed with venous reflux.

(248) 333-1172 x 301

Do you have VARICOSE VEINS?

Cardiology and Vascular Associates, P.C.42557 Woodward, Suite 100. Bloom�eld Hills, MI 48304

If yes, you may su�er from venous re�ux disease. Our cardiologists are

experts in the diagnosis and treatment for Venous Re�ux Disease.

Abdul R. Halabi. MD, FACC

EXPERT PHYSICIANS

THE BENEFITS FOR YOUOur physicians fellowship training and years of experience

provide them the skills and confidence to deliver outstanding results for you.    

Let CAVA help you return to a more active and enjoyable lifestyle

new CAVA_Brochure.pdf 1 6/27/12 9:47 AM

FREQUENTLY ASKED QUESTIONS

If so, you may be suffering from venous reflux

disease. Approximately 25 million people in the

United States suffer from this condition.

Traditionally, patients diagnosed with venous reflux

would undergo vein stripping surgery. Now, patients

can be treated with the Venefit™ procedure,

formerly known as the VNUS Closure™ procedure

— a minimally invasive and more comfortable

alternative to painful vein stripping surgery.

Do you experience the discomfort and swelling of varicose veins?

References

1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-14

2 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218

Nishit Choksi. MD, FACC

Our physicians are board certified in Cardiology and interventional cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, arthrectomy and stenting for lower extremity peripheral arterial vascular disease.

Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries.

www.cava.cc

Kirit C. Patel. MD, FACC

Michele De Gregorio. MD, FACC

Q: Is the Venefit™ procedure painful?

A: Patients generally report feeling little, if any, pain during

and after the procedure.

Q: How quickly can I resume normal activity?

A: Patients are encouraged to walk immediately following

the procedure, and most patients resume normal activities within 1-3 days.

Q: How soon after treatment will my symptoms improve?

A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure.

Q: Is there any scarring, bruising, or swelling after the procedure?

A: Most patients report minimal to no scarring, bruising, or swelling following the Venefit procedure.

Q: How is the Venefit procedure different from vein stripping?

A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Venefit procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery.1,2

Q: Is the Venefit procedure covered by insurance?

A: The Venefit procedure is covered by most health

insurances for patients diagnosed with venous reflux.

(248) 333-1172 x 301

Do you have VARICOSE VEINS?

Cardiology and Vascular Associates, P.C.42557 Woodward, Suite 100. Bloom�eld Hills, MI 48304

If yes, you may su�er from venous re�ux disease. Our cardiologists are

experts in the diagnosis and treatment for Venous Re�ux Disease.

Abdul R. Halabi. MD, FACC

EXPERT PHYSICIANS

THE BENEFITS FOR YOUOur physicians fellowship training and years of experience

provide them the skills and confidence to deliver outstanding results for you.    

Let CAVA help you return to a more active and enjoyable lifestyle

new CAVA_Brochure.pdf 1 6/27/12 9:47 AM

FREQUENTLY ASKED QUESTIONS

If so, you may be suffering from venous reflux

disease. Approximately 25 million people in the

United States suffer from this condition.

Traditionally, patients diagnosed with venous reflux

would undergo vein stripping surgery. Now, patients

can be treated with the Venefit™ procedure,

formerly known as the VNUS Closure™ procedure

— a minimally invasive and more comfortable

alternative to painful vein stripping surgery.

Do you experience the discomfort and swelling of varicose veins?

References

1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-14

2 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218

Nishit Choksi. MD, FACC

Our physicians are board certified in Cardiology and interventional cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, arthrectomy and stenting for lower extremity peripheral arterial vascular disease.

Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries.

www.cava.cc

Kirit C. Patel. MD, FACC

Michele De Gregorio. MD, FACC

Q: Is the Venefit™ procedure painful?

A: Patients generally report feeling little, if any, pain during

and after the procedure.

Q: How quickly can I resume normal activity?

A: Patients are encouraged to walk immediately following

the procedure, and most patients resume normal activities within 1-3 days.

Q: How soon after treatment will my symptoms improve?

A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure.

Q: Is there any scarring, bruising, or swelling after the procedure?

A: Most patients report minimal to no scarring, bruising, or swelling following the Venefit procedure.

Q: How is the Venefit procedure different from vein stripping?

A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Venefit procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery.1,2

Q: Is the Venefit procedure covered by insurance?

A: The Venefit procedure is covered by most health

insurances for patients diagnosed with venous reflux.

(248) 333-1172 x 301

Do you have VARICOSE VEINS?

Cardiology and Vascular Associates, P.C.42557 Woodward, Suite 100. Bloom�eld Hills, MI 48304

If yes, you may su�er from venous re�ux disease. Our cardiologists are

experts in the diagnosis and treatment for Venous Re�ux Disease.

Abdul R. Halabi. MD, FACC

EXPERT PHYSICIANS

THE BENEFITS FOR YOUOur physicians fellowship training and years of experience

provide them the skills and confidence to deliver outstanding results for you.    

Let CAVA help you return to a more active and enjoyable lifestyle

new CAVA_Brochure.pdf 1 6/27/12 9:47 AM

EXPERT PHYSICIANS

Our physicians are board certified in Cardiology and Interventional Cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, atherectomy and stenting for lower extremity peripheral arterial disease.

Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries.

Vascular Center of Michigan5701 Bow Pointe Dr. Suite 210. Clarkston, MI 48346

Cardiology and Vascular Associates, P.C.42557 Woodward, Suite 200. Bloomfield Hills, MI 48304

5701 Bow Pointe Dr. Suite 205. Clarkston, MI 48346

(248) 365-6900

FREQUENTLY ASKED QUESTIONS

If so, you may be suffering from venous reflux

disease. Approximately 25 million people in the

United States suffer from this condition.

Traditionally, patients diagnosed with venous reflux

would undergo vein stripping surgery. Now, patients

can be treated with the Venefit™ procedure,

formerly known as the VNUS Closure™ procedure

— a minimally invasive and more comfortable

alternative to painful vein stripping surgery.

Do you experience the discomfort and swelling of varicose veins?

References

1 LurieF, Creton D, Eklof B, Kabnick LS, Kistner RL, Pichot O, et al. Prospective randomized study of endovenous radiofrequency obliteration. (Closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). J Vasc Surg 2003;38;2:207-14

2 Hinchliffe RJ, et al. A prospective randomised controlled trial of VNUS Closure versus Surgery for the treatment of recurrent long saphenous variscose veins. Eur J Vasc Endovasc Surg 2006 Feb;31;2:212-218

Nishit Choksi. MD, FACC

Our physicians are board certified in Cardiology and interventional cardiology with extensive experience in diagnostic and interventional procedures of the heart and peripheral vascular system. In addition to vein ablation, our physicians perform angioplasty, arthrectomy and stenting for lower extremity peripheral arterial vascular disease.

Additional areas of expertise include percutaneous coronary revascularization, endovascular abdominal aortic aneurysm repair and percutaneous intervention of the renal and carotid arteries.

www.cava.cc

Kirit C. Patel. MD, FACC

Michele De Gregorio. MD, FACC

Q: Is the Venefit™ procedure painful?

A: Patients generally report feeling little, if any, pain during

and after the procedure.

Q: How quickly can I resume normal activity?

A: Patients are encouraged to walk immediately following

the procedure, and most patients resume normal activities within 1-3 days.

Q: How soon after treatment will my symptoms improve?

A: Most patients report a noticeable improvement in their symptoms within 1-2 weeks following the procedure.

Q: Is there any scarring, bruising, or swelling after the procedure?

A: Most patients report minimal to no scarring, bruising, or swelling following the Venefit procedure.

Q: How is the Venefit procedure different from vein stripping?

A: During vein stripping, incisions are made in the groin and calf, and a stripper tool is threaded through the diseased vein to pull the vein out of the leg. With the Venefit procedure, only one small incision is made at the insertion site and the vein is then closed and left in place. This minimally invasive approach virtually eliminates pain and bruising associated with vein stripping surgery.1,2

Q: Is the Venefit procedure covered by insurance?

A: The Venefit procedure is covered by most health

insurances for patients diagnosed with venous reflux.

(248) 333-1172 x 301

Do you have VARICOSE VEINS?

Cardiology and Vascular Associates, P.C.42557 Woodward, Suite 100. Bloom�eld Hills, MI 48304

If yes, you may su�er from venous re�ux disease. Our cardiologists are

experts in the diagnosis and treatment for Venous Re�ux Disease.

Abdul R. Halabi. MD, FACC

EXPERT PHYSICIANS

THE BENEFITS FOR YOUOur physicians fellowship training and years of experience

provide them the skills and confidence to deliver outstanding results for you.    

Let CAVA help you return to a more active and enjoyable lifestyle

new CAVA_Brochure.pdf 1 6/27/12 9:47 AM

Michele De GregorioMD, FACC

Abdul R. HalabiMD, FACC

Kirit C. PatelMD, FACC

UNDERSTANDING VENOUS REFLUX DISEASEHealthy leg veins contain valves that open and close to assist the return of blood back to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:

• Varicose veins • Leg heaviness and fatigue

• Leg pain • Skin changes

• Swollen limbs • Skin ulcers

• Nighttime cramps • Restless legs

VENOUS REFLUX DISEASE IS PROGRESSIVE — SYMPTOMS CAN WORSEN OVER TIME IF LEFT

UNTREATED.

A Serious Progressive Disorder

Photos courtesy of Rajabrata Sarkar, MD, PhD.

THE VENOUS SYSTEM ANATOMY The venous system is made up of a network of veins, including:• Superficial veins- veins located close to the surface of the skin. • Deep veins- larger veins located deep in the leg.• Perforator veins- veins that connect the superficial veins to the deep veins.

UNDERSTANDING VENOUS REFLUX DISEASEHealthy leg veins contain valves that open and close to assist the return of blood back to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:

• Varicose veins • Pain • Swollen limbs

• Leg heaviness and fatigue• Skin changes• Ulcers

VENOUS REFLUX DISEASE IS PROGRESSIVE — SYMPTOMS CAN WORSEN OVER TIME IF LEFT UNTREATED.

EXPERIENCE THE VENEFIT™ PROCEDURE

The Venefit procedure is performed on an outpatient basis. Using ultrasound, your physician will position the ClosureFAST™ catheter into the diseased vein through a small opening in the skin. The tiny catheter powered by radiofrequency (RF) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the vein is sealed closed. Once the diseased vein is closed, blood is re-routed to other healthy veins.

Following the procedure, a simple bandage is placed over the insertion site, and additional compression may be provided to aid healing. Your doctor may encourage you to walk, and to refrain from extended standing and strenuous activities for a period of time. Most patients who undergo the Venefit procedure typically resume normal activities within 1-3 days.

PROCEDURAL HIGHLIGHTS• Relief of symptoms

• Outpatient procedure

• Can be performed under local anesthesia

• Most patients resume normal activities within 1-3 days

• Good cosmetic outcome with minimal or no scarring, bruising or swelling1

Many factors contribute to the presence of venous reflux disease, including:

• Age • Gender • Family history • Heavy lifting Using ultrasound to scan your leg(s), your physician will determine if venous reflux is present.

• Multiple pregnancies• Obesity • Standing profession

ARE YOU A CANDIDATE?INDICATIONS: The Venefit procedures treat leg veins in the ™

superficial and perforating systems that have venous reflux, theunderlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient's condition.

CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the Venefit ™ Procedures.

POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation(when the catheter punctures the vein wall), thrombosis, pulmonary embolism (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), infection, nerve damage, arteriovenous

hematoma (bruising), and skin burn. Consult with a physician to receive more information.

The Venefit™ procedure, formerly known as the VNUS Closure™ procedure, treats venous reflux disease in the superficial venous system, often the underlying cause of painful varicose veins.

SaphenofemoralJunction

Femoral Vein(Deep System)

Femoral Vein(Deep System)

Great Saphenous Vein(Superficial System)

Small Saphenous Vein(Superficial System)

Skin

Perforating Vein

DeepVein

SuperficialVein

Perforating veins connect the deepsystem with the superficial system

A Serious Progressive Disorder* Individual results may vary.

VISUAL RESULTS1

1 Photo courtesy of Vein Institute of the North Shore, Beverly, MA

Healthy valves keep blood moving in one direction

Diseased valves cause blood to move in both directions, elevating venous pressure

Healthy Vein Valve Diseased Vein Valve

Disposable catheter inserted into vein

Controlled heat collapses vein

Catheter withdrawn, closing vein

Pre-treatment Post-treatment*

Varicose Veins

Swelling and Skin Discoloration

Skin Color andTexture Changes Venous Ulcers

Phot

os c

ourte

sy o

f Raj

abra

ta S

arka

r, M

D, P

hD.

fistula (an abnormal connection between an artery and a vein),

THE VENOUS SYSTEM ANATOMY The venous system is made up of a network of veins, including:• Superficial veins- veins located close to the surface of the skin. • Deep veins- larger veins located deep in the leg.• Perforator veins- veins that connect the superficial veins to the deep veins.

UNDERSTANDING VENOUS REFLUX DISEASEHealthy leg veins contain valves that open and close to assist the return of blood back to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:

• Varicose veins • Pain • Swollen limbs

• Leg heaviness and fatigue• Skin changes• Ulcers

VENOUS REFLUX DISEASE IS PROGRESSIVE — SYMPTOMS CAN WORSEN OVER TIME IF LEFT UNTREATED.

EXPERIENCE THE VENEFIT™ PROCEDURE

The Venefit procedure is performed on an outpatient basis. Using ultrasound, your physician will position the ClosureFAST™ catheter into the diseased vein through a small opening in the skin. The tiny catheter powered by radiofrequency (RF) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the vein is sealed closed. Once the diseased vein is closed, blood is re-routed to other healthy veins.

Following the procedure, a simple bandage is placed over the insertion site, and additional compression may be provided to aid healing. Your doctor may encourage you to walk, and to refrain from extended standing and strenuous activities for a period of time. Most patients who undergo the Venefit procedure typically resume normal activities within 1-3 days.

PROCEDURAL HIGHLIGHTS• Relief of symptoms

• Outpatient procedure

• Can be performed under local anesthesia

• Most patients resume normal activities within 1-3 days

• Good cosmetic outcome with minimal or no scarring, bruising or swelling1

Many factors contribute to the presence of venous reflux disease, including:

• Age • Gender • Family history • Heavy lifting Using ultrasound to scan your leg(s), your physician will determine if venous reflux is present.

• Multiple pregnancies• Obesity • Standing profession

ARE YOU A CANDIDATE?INDICATIONS: The Venefit procedures treat leg veins in the ™

superficial and perforating systems that have venous reflux, theunderlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient's condition.

CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the Venefit ™ Procedures.

POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation(when the catheter punctures the vein wall), thrombosis, pulmonary embolism (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), infection, nerve damage, arteriovenous

hematoma (bruising), and skin burn. Consult with a physician to receive more information.

The Venefit™ procedure, formerly known as the VNUS Closure™ procedure, treats venous reflux disease in the superficial venous system, often the underlying cause of painful varicose veins.

SaphenofemoralJunction

Femoral Vein(Deep System)

Femoral Vein(Deep System)

Great Saphenous Vein(Superficial System)

Small Saphenous Vein(Superficial System)

Skin

Perforating Vein

DeepVein

SuperficialVein

Perforating veins connect the deepsystem with the superficial system

A Serious Progressive Disorder* Individual results may vary.

VISUAL RESULTS1

1 Photo courtesy of Vein Institute of the North Shore, Beverly, MA

Healthy valves keep blood moving in one direction

Diseased valves cause blood to move in both directions, elevating venous pressure

Healthy Vein Valve Diseased Vein Valve

Disposable catheter inserted into vein

Controlled heat collapses vein

Catheter withdrawn, closing vein

Pre-treatment Post-treatment*

Varicose Veins

Swelling and Skin Discoloration

Skin Color andTexture Changes Venous Ulcers

Phot

os c

ourte

sy o

f Raj

abra

ta S

arka

r, M

D, P

hD.

fistula (an abnormal connection between an artery and a vein),

THE VENOUS SYSTEM ANATOMY The venous system is made up of a network of veins, including:• Superficial veins- veins located close to the surface of the skin. • Deep veins- larger veins located deep in the leg.• Perforator veins- veins that connect the superficial veins to the deep veins.

UNDERSTANDING VENOUS REFLUX DISEASEHealthy leg veins contain valves that open and close to assist the return of blood back to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:

• Varicose veins • Pain • Swollen limbs

• Leg heaviness and fatigue• Skin changes• Ulcers

VENOUS REFLUX DISEASE IS PROGRESSIVE — SYMPTOMS CAN WORSEN OVER TIME IF LEFT UNTREATED.

EXPERIENCE THE VENEFIT™ PROCEDURE

The Venefit procedure is performed on an outpatient basis. Using ultrasound, your physician will position the ClosureFAST™ catheter into the diseased vein through a small opening in the skin. The tiny catheter powered by radiofrequency (RF) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the vein is sealed closed. Once the diseased vein is closed, blood is re-routed to other healthy veins.

Following the procedure, a simple bandage is placed over the insertion site, and additional compression may be provided to aid healing. Your doctor may encourage you to walk, and to refrain from extended standing and strenuous activities for a period of time. Most patients who undergo the Venefit procedure typically resume normal activities within 1-3 days.

PROCEDURAL HIGHLIGHTS• Relief of symptoms

• Outpatient procedure

• Can be performed under local anesthesia

• Most patients resume normal activities within 1-3 days

• Good cosmetic outcome with minimal or no scarring, bruising or swelling1

Many factors contribute to the presence of venous reflux disease, including:

• Age • Gender • Family history • Heavy lifting Using ultrasound to scan your leg(s), your physician will determine if venous reflux is present.

• Multiple pregnancies• Obesity • Standing profession

ARE YOU A CANDIDATE?INDICATIONS: The Venefit procedures treat leg veins in the ™

superficial and perforating systems that have venous reflux, theunderlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient's condition.

CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the Venefit ™ Procedures.

POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation(when the catheter punctures the vein wall), thrombosis, pulmonary embolism (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), infection, nerve damage, arteriovenous

hematoma (bruising), and skin burn. Consult with a physician to receive more information.

The Venefit™ procedure, formerly known as the VNUS Closure™ procedure, treats venous reflux disease in the superficial venous system, often the underlying cause of painful varicose veins.

SaphenofemoralJunction

Femoral Vein(Deep System)

Femoral Vein(Deep System)

Great Saphenous Vein(Superficial System)

Small Saphenous Vein(Superficial System)

Skin

Perforating Vein

DeepVein

SuperficialVein

Perforating veins connect the deepsystem with the superficial system

A Serious Progressive Disorder* Individual results may vary.

VISUAL RESULTS1

1 Photo courtesy of Vein Institute of the North Shore, Beverly, MA

Healthy valves keep blood moving in one direction

Diseased valves cause blood to move in both directions, elevating venous pressure

Healthy Vein Valve Diseased Vein Valve

Disposable catheter inserted into vein

Controlled heat collapses vein

Catheter withdrawn, closing vein

Pre-treatment Post-treatment*

Varicose Veins

Swelling and Skin Discoloration

Skin Color andTexture Changes Venous Ulcers

Phot

os c

ourte

sy o

f Raj

abra

ta S

arka

r, M

D, P

hD.

fistula (an abnormal connection between an artery and a vein),

THE VENOUS SYSTEM ANATOMY The venous system is made up of a network of veins, including:• Superficial veins- veins located close to the surface of the skin. • Deep veins- larger veins located deep in the leg.• Perforator veins- veins that connect the superficial veins to the deep veins.

UNDERSTANDING VENOUS REFLUX DISEASEHealthy leg veins contain valves that open and close to assist the return of blood back to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:

• Varicose veins • Pain • Swollen limbs

• Leg heaviness and fatigue• Skin changes• Ulcers

VENOUS REFLUX DISEASE IS PROGRESSIVE — SYMPTOMS CAN WORSEN OVER TIME IF LEFT UNTREATED.

EXPERIENCE THE VENEFIT™ PROCEDURE

The Venefit procedure is performed on an outpatient basis. Using ultrasound, your physician will position the ClosureFAST™ catheter into the diseased vein through a small opening in the skin. The tiny catheter powered by radiofrequency (RF) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the vein is sealed closed. Once the diseased vein is closed, blood is re-routed to other healthy veins.

Following the procedure, a simple bandage is placed over the insertion site, and additional compression may be provided to aid healing. Your doctor may encourage you to walk, and to refrain from extended standing and strenuous activities for a period of time. Most patients who undergo the Venefit procedure typically resume normal activities within 1-3 days.

PROCEDURAL HIGHLIGHTS• Relief of symptoms

• Outpatient procedure

• Can be performed under local anesthesia

• Most patients resume normal activities within 1-3 days

• Good cosmetic outcome with minimal or no scarring, bruising or swelling1

Many factors contribute to the presence of venous reflux disease, including:

• Age • Gender • Family history • Heavy lifting Using ultrasound to scan your leg(s), your physician will determine if venous reflux is present.

• Multiple pregnancies• Obesity • Standing profession

ARE YOU A CANDIDATE?INDICATIONS: The Venefit procedures treat leg veins in the ™

superficial and perforating systems that have venous reflux, theunderlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient's condition.

CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the Venefit ™ Procedures.

POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation(when the catheter punctures the vein wall), thrombosis, pulmonary embolism (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), infection, nerve damage, arteriovenous

hematoma (bruising), and skin burn. Consult with a physician to receive more information.

The Venefit™ procedure, formerly known as the VNUS Closure™ procedure, treats venous reflux disease in the superficial venous system, often the underlying cause of painful varicose veins.

SaphenofemoralJunction

Femoral Vein(Deep System)

Femoral Vein(Deep System)

Great Saphenous Vein(Superficial System)

Small Saphenous Vein(Superficial System)

Skin

Perforating Vein

DeepVein

SuperficialVein

Perforating veins connect the deepsystem with the superficial system

A Serious Progressive Disorder* Individual results may vary.

VISUAL RESULTS1

1 Photo courtesy of Vein Institute of the North Shore, Beverly, MA

Healthy valves keep blood moving in one direction

Diseased valves cause blood to move in both directions, elevating venous pressure

Healthy Vein Valve Diseased Vein Valve

Disposable catheter inserted into vein

Controlled heat collapses vein

Catheter withdrawn, closing vein

Pre-treatment Post-treatment*

Varicose Veins

Swelling and Skin Discoloration

Skin Color andTexture Changes Venous Ulcers

Phot

os c

ourte

sy o

f Raj

abra

ta S

arka

r, M

D, P

hD.

fistula (an abnormal connection between an artery and a vein),

THE VENOUS SYSTEM ANATOMYThe venous system is made up of a network of veins, including:

• Superficial veins- veins located close to the surface of the skin.• Deep veins- larger veins located deep in the leg.• Perforator veins- veins that connect the superficial veins to the

deep veins.

PROCEDURAL HIGHLIGHTS• Relief of symptoms

• Outpatient procedure

• Can be performed under local anesthesia

• Most patients resume normal activities within 2-4 days

• Good cosmetic outcome with minimal or no scarring,

bruising or swelling1

VISUAL RESULTS1

*Individual results may vary. 1Photo courtesy of Vein Institute of the North Shore, Beverly, MA

INDICATIONS: ™The Vein Ablation procedures treat leg veins

in the superficial and perforating systems that have venous reflux, the underlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient’s condition.

CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the Vein Ablation ™ Procedures.

POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation (when the catheter punctures the vein wall), thrombosis, pulmonary embolism (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), infection, nerve damage, arteriovenous fistula (an abnormal connection between an artery and a vein), hematoma (bruising), and skin burn. Consult with a physician to receive more information.

THE VENOUS SYSTEM ANATOMY The venous system is made up of a network of veins, including:• Superficial veins- veins located close to the surface of the skin. • Deep veins- larger veins located deep in the leg.• Perforator veins- veins that connect the superficial veins to the deep veins.

UNDERSTANDING VENOUS REFLUX DISEASEHealthy leg veins contain valves that open and close to assist the return of blood back to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:

• Varicose veins • Pain • Swollen limbs

• Leg heaviness and fatigue• Skin changes• Ulcers

VENOUS REFLUX DISEASE IS PROGRESSIVE — SYMPTOMS CAN WORSEN OVER TIME IF LEFT UNTREATED.

EXPERIENCE THE VENEFIT™ PROCEDURE

The Venefit procedure is performed on an outpatient basis. Using ultrasound, your physician will position the ClosureFAST™ catheter into the diseased vein through a small opening in the skin. The tiny catheter powered by radiofrequency (RF) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the vein is sealed closed. Once the diseased vein is closed, blood is re-routed to other healthy veins.

Following the procedure, a simple bandage is placed over the insertion site, and additional compression may be provided to aid healing. Your doctor may encourage you to walk, and to refrain from extended standing and strenuous activities for a period of time. Most patients who undergo the Venefit procedure typically resume normal activities within 1-3 days.

PROCEDURAL HIGHLIGHTS• Relief of symptoms

• Outpatient procedure

• Can be performed under local anesthesia

• Most patients resume normal activities within 1-3 days

• Good cosmetic outcome with minimal or no scarring, bruising or swelling1

Many factors contribute to the presence of venous reflux disease, including:

• Age • Gender • Family history • Heavy lifting Using ultrasound to scan your leg(s), your physician will determine if venous reflux is present.

• Multiple pregnancies• Obesity • Standing profession

ARE YOU A CANDIDATE?INDICATIONS: The Venefit procedures treat leg veins in the ™

superficial and perforating systems that have venous reflux, theunderlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient's condition.

CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the Venefit ™ Procedures.

POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation(when the catheter punctures the vein wall), thrombosis, pulmonary embolism (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), infection, nerve damage, arteriovenous

hematoma (bruising), and skin burn. Consult with a physician to receive more information.

The Venefit™ procedure, formerly known as the VNUS Closure™ procedure, treats venous reflux disease in the superficial venous system, often the underlying cause of painful varicose veins.

SaphenofemoralJunction

Femoral Vein(Deep System)

Femoral Vein(Deep System)

Great Saphenous Vein(Superficial System)

Small Saphenous Vein(Superficial System)

Skin

Perforating Vein

DeepVein

SuperficialVein

Perforating veins connect the deepsystem with the superficial system

A Serious Progressive Disorder* Individual results may vary.

VISUAL RESULTS1

1 Photo courtesy of Vein Institute of the North Shore, Beverly, MA

Healthy valves keep blood moving in one direction

Diseased valves cause blood to move in both directions, elevating venous pressure

Healthy Vein Valve Diseased Vein Valve

Disposable catheter inserted into vein

Controlled heat collapses vein

Catheter withdrawn, closing vein

Pre-treatment Post-treatment*

Varicose Veins

Swelling and Skin Discoloration

Skin Color andTexture Changes Venous Ulcers

Phot

os c

ourte

sy o

f Raj

abra

ta S

arka

r, M

D, P

hD.

fistula (an abnormal connection between an artery and a vein),

Healthy Vein Valve Diseased Vein Valve

Healthy valves keep blood moving in one direction

Diseased valves cause blood to move in both directions, elevating venous pressure

VEIN ABLATION PROCEDURESThe Vein Ablation procedure is performed on an outpatient basis.

Using ultrasound, your physician will position the Ablation catheter into the diseased vein through a small opening in the skin. The tiny catheter powered by radiofrequency (RF) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the vein is sealed closed. Once the diseased vein is closed, blood is re-routed to other healthy veins.

Following the procedure, a simple bandage is placed over the insertion site, and additional compression will be provided to aid healing. Your doctor will encourage you to walk, and to refrain from extended standing and strenuous activities for a period of time. Most patients who undergo the Vein Ablation procedure typically resume normal activities within 2-4 days.

ARE YOU A CANDIDATE?

Many factors contribute to the presence of venous reflux disease, including:

• Age • Multiple pregnacies

• Gender • Obesity

• Family history • Standing or sitting profession

• Heavy lifting

Using ultrasound to scan your leg(s), your physician will determine if venous reflux is present as well as the level and severity of venous reflux.