1
The world’s leading continuous glucose monitoring technology 1 has unsurpassed 14-day accuracy, 2 with optional real-time alarms for adults and kids with diabetes. 3 Get details on the growing market for this life-changing tech and why the FreeStyle Libre 2 system is a standout. IMPORTANT SAFETY INFORMATION The FreeStyle Libre 2 Flash Glucose Monitoring System is a continuous glucose monitoring (CGM) device with real time alarms capability indicated for the management of diabetes in persons age 4 and older.* WARNINGS/LIMITATIONS* The System must not be used with automated insulin dosing (AID) systems, including closed loop and insulin suspend systems. Remove the sensor before MRI, CT scan, X-ray, or diathermy treatment. Do not take high doses of vitamin C (more than 500 mg per day), as this may falsely raise your Sensor readings. Failure to use the System according to the instructions for use may result in missing a severe low blood glucose or high blood glucose event and/or making a treatment decision that may result in injury. If glucose alarms and readings from the System do not match symptoms or expectations, use a fingerstick blood glucose value to make diabetes treatment decisions. Seek medical attention when appropriate and contact Abbott Toll Free (855-632-8658) or visit *www.freestylelibre.us for detailed indications for use and safety information. *Please refer to www.freestylelibre.us for the indications and important safety information. ADC-23440 v 1.0 REFERENCES 1. Data on file, Abbott Diabetes Care. Data based on the number of users worldwide for the FreeStyle Libre system compared to the number of users for other leading personal-use, sensor-based glucose monitoring systems. 2. FreeStyle Libre 2 system user manual. 3. For children age 4 and older. 4. International Diabetes Federation Diabetes Atlas, Ninth Edition, 2019. https://www.diabetesatlas.org/upload/resources/material/20200302_133351_IDFATLAS9e-final-web.pdf. 5. Centers for Disease Control and Prevention, National Diabetes Statistics Report, 2020. https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdf 6. Data on file, Abbott Diabetes Care. 7. Based on FDA iCGM special controls. 8. Data on file, Abbott Diabetes Care. 9. Dexcom G6 CGM User Guide. 10. FreeStyle Libre 2 system user manual. Dexcom G6 CGM User Guide. Based on low glucose alarms set at 70 mg/dL for pediatrics. TO LEARN MORE, PLEASE VISIT FREESTYLELIBRE.US FreeStyle Libre ® 2 System IMPROVING LIFE FOR PEOPLE WITH DIABETES MEETING THE HIGHEST LEVEL OF ACCURACY STANDARD, 7 EVERY MINUTE FREESTYLE LIBRE 2 IS THE LONGEST-LASTING WEARABLE INTEGRATED CONTINUOUS GLUCOSE MONITORING (iCGM) FOR UP TO 14 DAYS SUPERIOR ACCURACY ON DAY 1 Mean absolute relative difference (MARD) is the most common metric to measure the performance of CGMs. Lower MARD equals better accuracy. 18.5 % 8 Other available iCGM MARD 9.1 % 8 FreeStyle Libre 2 MARD BETTER REAL-TIME ALARM PERFORMANCE FEWER FALSE ALARMS IN CHILDREN COMPARED TO THE OTHER AVAILABLE iCGM 10 1 / 3 ONLY iCGM WITH UNSURPASSED 14-DAY ACCURACY 2 9.8 % Other available iCGM 9.3 % FreeStyle Libre 2 OVERALL MARD OVER 14 DAYS 8 OVERALL MARD OVER 10 DAYS 9 USE IS 40% LONGER THAN OTHER WEARABLE GLUCOSE SENSORS Other available iCGM UP-TO-THE-MINUTE READINGS 288 READINGS PER DAY (MEASURES GLUCOSE EVERY 5 MINUTES – A LOT CAN CHANGE MINUTE TO MINUTE) 1,440 FreeStyle Libre 2 READINGS PER DAY (MEASURES GLUCOSE EVERY MINUTE, WHICH IS 5 TIMES MORE OFTEN THAN COMPETITORS) AN INCREASING NEED FOR ACCESS TO DIABETES TECHNOLOGIES 4 ADULTS WITH DIABETES (20–79 YEARS) AND TOTAL DIABETES-RELATED HEALTH EXPENDITURE IN 2019 (IN USD) DIABETES CASES TOTAL HEALTHCARE EXPENSES $109B $294.6B 116.4M 31M 19.4M USA PAKISTAN $52.3B 16.8M BRAZIL CHINA INDIA 77M $1B– < $10B $1B– < $10B DIABETES: A GROWING GLOBAL CONCERN GLOBAL PREVALENCE OF DIABETES IN ADULTS AGES 20–79 4 ABOUT 10.5% OF THE U.S. POPULATION HAS DIABETES 5 463M GLOBAL DIABETES CASES IN ADULTS AGES 20-79 4 26.9M DIAGNOSED 7M UNDIAGNOSED 2000 2019 9.3% 4.6% >2M GLOBAL USERS OF FREESTYLE LIBRE PRODUCTS 6 ABBOTT.COM/INVESTORS

FreeStyle Libre - Abbott Laboratories...FreeStyle Libre 2 system is a standout. IMPORTANT SAFETY INFORMATION The FreeStyle Libre 2 Flash Glucose Monitoring System is a continuous glucose

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Page 1: FreeStyle Libre - Abbott Laboratories...FreeStyle Libre 2 system is a standout. IMPORTANT SAFETY INFORMATION The FreeStyle Libre 2 Flash Glucose Monitoring System is a continuous glucose

The world’s leading continuous glucose monitoring technology1 has unsurpassed 14-day accuracy,2 with optional real-time alarms for adults and kids with diabetes.3 Get details on the growing market for this life-changing tech and why the FreeStyle Libre 2 system is a standout.

IMPORTANT SAFETY INFORMATIONThe FreeStyle Libre 2 Flash Glucose Monitoring System is a continuous glucose monitoring (CGM) device with real time alarms capability indicated for the management of diabetes in persons age 4 and older.*

WARNINGS/LIMITATIONS*The System must not be used with automated insulin dosing (AID) systems, including closed loop and insulin suspend systems. Remove the sensor before MRI, CT scan, X-ray, or diathermy treatment. Do not take high doses of vitamin C (more than 500 mg per day), as this may falsely raise your Sensor readings. Failure to use the System according to the instructions for use may result in missing a severe low blood glucose or high blood glucose event and/or making a treatment decision that may result in injury. If glucose alarms and readings from the System do not match symptoms or expectations, use a fingerstick blood glucose value to make diabetes treatment decisions. Seek medical attention when appropriate and contact Abbott Toll Free (855-632-8658) or visit *www.freestylelibre.us for detailed indications for use and safety information.*Please refer to www.freestylelibre.us for the indications and important safety information.ADC-23440 v 1.0

REFERENCES1. Data on file, Abbott Diabetes Care. Data based on the number of users worldwide for the FreeStyle Libre system compared to the number of users for other leading personal-use, sensor-based glucose monitoring systems. 2. FreeStyle Libre 2 system user manual. 3. For children age 4 and older. 4. International Diabetes Federation Diabetes Atlas, Ninth Edition, 2019. https://www.diabetesatlas.org/upload/resources/material/20200302_133351_IDFATLAS9e-final-web.pdf. 5. Centers for Disease Control and Prevention, National Diabetes Statistics Report, 2020. https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdf 6. Data on file, Abbott Diabetes Care. 7. Based on FDA iCGM special controls. 8. Data on file, Abbott Diabetes Care. 9. Dexcom G6 CGM User Guide. 10. FreeStyle Libre 2 system user manual. Dexcom G6 CGM User Guide. Based on low glucose alarms set at 70 mg/dL for pediatrics.

TO LEARN MORE, PLEASE VISIT FREESTYLELIBRE.US

FreeStyle Libre® 2 System IMPROVING LIFE FOR PEOPLE WITH DIABETES

MEETING THE HIGHEST LEVEL OF ACCURACY STANDARD,7 EVERY MINUTE

FREESTYLE LIBRE 2 IS THE LONGEST-LASTING WEARABLE INTEGRATED CONTINUOUS GLUCOSE MONITORING (iCGM) FOR UP TO 14 DAYS

SUPERIOR ACCURACY ON DAY 1

Mean absolute relative difference (MARD) is the most common metric to measure the performance of CGMs. Lower MARD equals better accuracy.

18.5%8

Other available iCGMMARD

9.1%8

FreeStyle Libre 2MARD

BETTER REAL-TIME ALARM PERFORMANCE

FEWER FALSE ALARMS IN CHILDREN COMPARED TO THE OTHER AVAILABLE iCGM101/3

ONLY iCGM WITH UNSURPASSED 14-DAY ACCURACY2

9.8%Other available iCGM

9.3%FreeStyle Libre 2OVERALL MARD OVER 14 DAYS8

OVERALL MARD OVER 10 DAYS9

USE IS 40% LONGER THAN OTHER WEARABLE GLUCOSE SENSORS

Other available iCGM

UP-TO-THE-MINUTE READINGS

288READINGS PER DAY(MEASURES GLUCOSE EVERY 5 MINUTES – A LOT CAN CHANGE MINUTE TO MINUTE)

1,440FreeStyle Libre 2READINGS PER DAY(MEASURES GLUCOSE EVERY MINUTE, WHICH IS 5 TIMES MORE OFTEN THAN COMPETITORS)

AN INCREASING NEED FOR ACCESS TO DIABETES TECHNOLOGIES4

ADULTS WITH DIABETES (20–79 YEARS) AND TOTAL DIABETES-RELATED HEALTH EXPENDITURE IN 2019 (IN USD)

DIABETES CASESTOTAL HEALTHCARE EXPENSES

$109B$294.6B116.4M

31M19.4M

USA PAKISTAN

$52.3B

16.8M

BRAZILCHINA INDIA

77M

$1B– <$10B

$1B– <$10B

DIABETES: A GROWING GLOBAL CONCERN

GLOBAL PREVALENCE OF DIABETES IN

ADULTS AGES 20–794

ABOUT 10.5% OF THE U.S. POPULATION

HAS DIABETES5

463MGLOBAL DIABETES CASES

IN ADULTS AGES 20-79 4

26.9M DIAGNOSED

7M UNDIAGNOSED

2000 2019

9.3%

4.6% >2M GLOBAL USERS OF FREESTYLE LIBRE PRODUCTS6

ABBOTT.COM/INVESTORS