“Forget Antibodies. Use Aptamers!”

Opportunity for Employer Savings

Smoking employee costs the Employer an additional ~$3,000/year

40 Million employees work for large self-insured Companies

Opportunity for Life Insurance

Quick Facts for Smoking Individuals:

Life Insurance Premium Increase= 50-65%

Life Insurance Policies = 10 Million annually (USA)

The Problem of Testing for Tobacco Use

Tobacco Use

Nicotine Products

$2Results in minutes

Only anabasine detection available in the market: LC-MS

COST of Assay= ~$100Time = 1 day before Results

Trained Technician & Equipment needed

Anabasine is a definitive marker for Tobacco Use.

Nicotine products are negative for Anabasine.

Apta-basine™Test Strip (Y/N)

The Solution:

Quantify

Short-term Vision

Long-term Vision

Caffeine Theophylline

Apta-beacon™ (GQ-EXPAR)Demonstration Kit (Theophylline/Caffeine)

Selectivity:Distinguish just a few Atoms!

Current PlatformTest Strip

(Lateral Flow Platform)

ReconfigureColorimetric

Apta-basine™ Licensing Strategy

Apta-basine™Test Strip (Y/N)

$2/test X 50 million individuals =$100M Market

“Forget Antibodies. Use Aptamers!”