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The categories for today’s Jeopardy on Substance Use will be:

Opioids

Stimulants

Alcohol Use Disorder

Criterion A

Substance Induced

disorders

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800

Opioids Alcohol Use Disorders

Substance Induced

Disorders

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300

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800

Subst Use Disorders

Criterion A

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Stimulants

Row 1, Col 1

Opioids can be detected thru a urine drug test for this many hours after

administration of the opioid

What is 12-36 hours?

1,2

This type of liver disease may occur in up to 90% of persons who

inject opioids

What is hepatitis C?

1,3

HIV, hepatitis, tuberculosis, and this cardiac related condition are serious medical problems

for IV opiate users

What is bacterial endocarditis?

1,4

This physical sign of opiate withdrawal is also “seen” in

hallucinogen intoxication and stimulant intoxication

What is pupil dilation?

1,5

Opioid intoxication may be diagnosed by administering this opioid

antagonist challenge

What is naloxone (narcan)?

1,6

These two symptoms are associated with more severe opiate

withdrawal and are often not seen in routine clinical practice

What is piloerection & fever?

1,7

Suboxone is a combination of these two medications

What is naloxone (narcan) & buprenorphine?

1,8

Yawning, insomnia, dizziness, diarrheaThis one is not part of opiate

withdrawal

What is lightneadedness?Withdrawal: dysphoria, N/V, muscle aches,

lacrimation/rhinorrhea, pupil dilation/piloerection, fever, sweating,

1,9

Signs of opioid intoxication are pupil constriction, drowsiness/coma, impaired attention or memory,

and this

What is slurred speech?

2,1

This can differentiate PCP intoxication & stimulant

intoxication from each other

What is a urine drug test?(Clinical picture is similar though rotary nystagmus may be

seen in PCP intoxication but not stimulant)

2,2

Cocaine users often use sedative substances--most often this

substance--to reduce insomnia, nervousness, and other unpleasant side effects

What is alcohol?

2,3

Amphetamine type stimulant users often use sedative substances--most often this substance--to

reduce insomnia, nervousness, and other unpleasant side effects

What is marijuana?

2,4

This sign is often present and is a reliable measure of stimulant

withdrawal

What is a bradycardia?

2,5

Bipolar disorder, schizophrenia, other substance use disorders, and

this personality disorder in particular are risk factors for

stimulant use disorder

What is antisocial personality disorder?

2,6

This type of sample can be used to detect use of a stimulant up to

90 days after the use

What is a hair sample

2,7

These two forms of cocaine administration have the most

rapid onset of action

What is inhalation and injection?

2,8

A speedball is the combination of cocaine and this drug

What is heroin?

2,9

Cocaine increases the levels of glutamate and this neurotransmitter

What is dopamine?

3,1

In terms of operant conditioning, the alcohol induced buzz/high is this;

also tolerance results in the lack of this

What is positive reinforcement?

3,2

In terms of operant conditioning, consuming alcohol to stave off alcohol withdrawal symptoms

results in this

What is negative reinforcement?

3,3

Most substance induced disorders resolve within this amount of time after the cessation of acute withdrawal, the cessation of severe

intoxication, or the use of the substance.

What is 1 month?

(Most improve within days to weeks of abstinence)

3,4

The prevalence of alcohol use disorder in this sex is twice as much as

the other

What is males?Males ~12%, Females ~5%

3,5

For an individual who has a close relative (parent) with an alcohol use

disorder, their risk is this many times higher than normal

What are 3-4 times?

3,6

Alcohol metabolizing enzyme genetic polymorphisms result in flushing,

palpitations, & possibly more severe reactions in individuals

of this race when they consume alcohol

What is Asians?Japanese, Chinese, and Koreans are at lower risk for

Alcohol Use Disorders

3,7

Elevations in these two lab test results are sensitive indicators of ongoing heavy drinking and can be used to

monitor abstinence

What is gamma-glutamyltransferase (GGT) and carbohydrate-deficient transferrin (CDT)?

3,8

While elevation of GGT, CDT, and this test indicates a history of heavy drinking, GGT & CDT test may also

be useful in detecting a relapse to heavy drinking, but

this test is not

What is mean corpuscular volume (MCV)?Not useful for monitoring due to long half life of RBC’s

3,9

The patients with bipolar disorder, schizophrenia, & this personality

disorder have a markedly high rate of co-morbid alcohol

use disorder

What is Antisocial Personality Disorder?

4,1

Substance use disorder pts, especially those with severe disorder, have an

underlying change in this which persists even beyond detoxification

What is brain circuitry?

4,2

Impaired control, Social impairment, Risky use, or Pharmacological criteria

Continued use despite persistent or recurring interpersonal problems

What is social impairment?

4,3


A desire to cut down or unsuccessful attempts decrease or stop use refers

to this Criterion A

What is impaired control?

4,4


Pharmacological criteria refers to “putting up” with these two

phenomenon

What is tolerance & withdrawal?

4,5


Taking the substance in larger amounts or over a longer time

period than intended refers to this Criterion A


4,6


Use in physically hazardous situations or continued use despite knowledge the substance is causing or worsening a

medical problem is called this

What is risky use? .

4,7


Spending a great deal of time obtaining, using, or recovering from the substance

use refers to this Criterion A


4,8


Failure to fulfill major obligations at work, home, or school refers to this

Criterion A

What is social impairment

4,9


Craving refers to this Criterion A


5,1

Caffeine intoxication may induce a sleep disorder or this type of substance induced disorder

What is anxiety?

5,2

Marijuana intoxication may induce anxiety disorders, sleep disorders,

and this type of substance induced disorder

What is Psychotic disorder?

5,3

The hallucinogen phencyclidine may induce psychotic disorders,

anxiety disorders, delirium, & this type of substance

induced disorders

What are mood disorders?(both bipolar & depressive)

5,4

Opioid intoxication may induce sleep disorders, sexual dysfunction,

delirium, & this type of substance induced disorder

What is depressive disorders?

5,5

Opioid intoxication will not, but opioid withdrawal may induce this

type of substance disorder

What are anxiety?

5,6

Alcohol & sedative/hypnotic intoxication may both induce the same type of substance disorders

except sedative/hypnotic intoxication will NOT

induce this

What is anxiety?Psychotic, Bipolar, Depressive, Sleep, Sexual Dysfunction, Delirium, Neurocognitive disorders

5,7

Intoxication, but not withdrawal, of stimulants such as cocaine may induce sexual dysfunction, delirium

& this type of substance induced disorder

What are psychotic disorders?

5,8

Intoxication & withdrawal of stimulants such as cocaine may

induce, anxiety, OCD, sleep, & this type of substance induced disorder

What is mood?(both bipolar & depressive)

5,9

Inhalants and this type of substance do not cause a withdrawal

What is hallucinogens?

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