Grow your practice and competitive edge with MEDISCA’s comprehensive FizzMixTM Kit. We want to set you up for success as quickly as possible!

CUSTOMIZED EFFERVESCENTCOMPOUNDING FORMULATIONS

FIZZMIXTM KIT

WHY USE AN EFFERVESCENT DELIVERY SYSTEM?

Effervescent delivery systems such as tablets or sachets are a popular and innovative way to approach compounding challenges, for example, large powder loads of multiple ingredients with varying densities. This dosage form is ideal for customized nutraceutical products including vitamins, minerals, herbal supplements and amino acids as well as pharmaceutical treatments such as anti-nausea, antacids, analgesics, antihistamines, antipyretics, antibiotics and sleep aids.

Benefits of effervescent dosage options:

• Combines the portability and stability of a capsule with the bioavailability of a solution

• Easy to compound high dose, multiple-ingredient formulations

• Improved compliance: highly palatable solutions due to superior bitterness-masking

• Easier to swallow than capsules or tablets

• Good gastrointestinal tolerance: effervescent formulations dissolve fully into a buffered solution

• Ideal for special patient populations: Pediatrics, geriatrics, patients who have undergone chemo or radiation therapy as well as patients with autism or Down syndrome

WHAT ’S INCLUDED IN THE FIZZMIX KIT ?MEDISCA has introduced a comprehensive kit which includes everything needed to quickly and easily compound customized effervescent formulations:

Product No.: 3042 Included in the kit: 1 x 500 g FizzMixTM Base

FizzMix Base (500 g)FizzMix™ Base is a sweetened, uniquely processed fine powder blend, containing all excipients needed to prepare effervescent formulations. This ready-to-use base eliminates the steps of weighing and mixing individual ingredients so you can now streamline the process of compounding effervescent powders or compressed tablet formulations.

Features & Benefits:

• Fast dissolution and extended fizzing effect1

• Versatility: innovative delivery method for a wide range of ingredients (nutraceuticals, herbal supplements, various APIs, etc.)

• No additional excipients required: simply add active ingredients and desired flavor(s)

• Excellent solubility & palatability: forms a clear solution, with no insoluble residue or film

• Free-flowing and stable: packaged in moisture-barrier bags to prevent loss of effervescence over time2

• Lactose and sugar free: suitable for patients with dietary restrictions

• Available in 100 g, 500 g, 1 Kg and 2.5 Kg formats1Use of room temperature water is recommended for best effervescence results 2Samples not packaged in moisture-barrier bags

FIZZMIXTM KIT – CUSTOMIZED EFFERVESCENT COMPOUNDING FORMULATIONS 2

Sachet Filling EquipmentMEDISCA’s Sachet Filling Equipment offers a fast, simple and convenient way to dispense various batch sizes of powder formulations. Specifically designed for MEDISCA’s Effervescent Delivery System, this device facilitates the accurate dispensing of medicated powder formulations in a wide range of dosages even at high drug loading content.

Simply choose the desired bin volume and load the pre-mixed powder into the sachet filling equipment for uniform fill weights!

Features & Benefits:

• Lightweight for easy handling and cleaning

• Highly durable thermal and mechanical resistant material

• Changeable parts for multiple sizes

• Calibrated cavities for dosage uniformity

• Teflon-free

• Additional bins sold separately

Product No.: 6592 Included in the kit: 1 Sachet Filling Equipment with Bins – 2.5 mL,

5.0 mL, 7.5 mL and 10.0 mL (32 of Each) & Powder Scraper

Moisture Barrier BagsThe Moisture Barrier Bag provides an elegant and cost-effective option for dispensing FizzMix effervescent powder formulations and other powdered dosage forms. These bags are heat-sealable and can be used for any application requiring superior tear and puncture resistance as well as protection from light, air and moisture.*The foil film material conforms to FDA Regulations PART 177-1520 CFR21 for direct food contact when used as supplied and in accordance with sound manufacturing practices.

Additional Features:

• Tear-notch for clean and easy opening

• Laminated OPP/PE/Foil/PE material

• Available in 2 sizes (70 x 80 mm for 2.5-5 mL and 100 x 80 mm for 7.5-10 mL)

Product No.: 6594, 6590 Included in the kit: Pk/100 – Moisture Barrier Bags (70 x 80 mm) and

Pk/100 – Moisture Barrier Bags (100 x 80 mm)

Customized FormulaMEDISCA NETWORK recognizes your need to get it right the first time, which is why for your first FizzMix effervescent powder formulation, MEDISCA NETWORK will provide you with a free customized sample formula of your choice to help get you started with confidence.

Formulas Available:

F 006 631 Ferrous Sulfate 165 mg per 7.5 mL Oral Effervescent Powder Blend for Reconstitution (Powder Blend, 30 x 7.5 mL Pouches)

F 006 636 Scopolamine Hydrobromide 75 µg per 2.5 mL Oral Effervescent Powder Blend for Reconstitution (Powder Blend, 30 x 2.5 mL Pouches)

F 006 655 Carnitine 500 mg per 7.5 mL Oral Effervescent Powder Blend for Reconstitution (Powder Blend, 30 x 7.5 mL Pouches)

F 006 945 L-Glutamine 500 mg per 5 mL Oral Effervescent Powder Blend for Reconstitution (Powder Blend, 30 x 5 mL Pouches)

F 006 946 Calcium Citrate 712 mg, Magnesium Citrate 619 mg, Zinc sulfate 34 mg per 10 mL Oral Effervescent Powder Blend for Reconstitution (Powder Blend, 30 x 10 mL Pouches)

F 006 947 Chondroitin sulfate 600 mg, Glucosamine Sulfate 750 mg per 7.5 mL Oral Effervescent Powder Blend for Reconstitution (Powder Blend, 30 x 7.5 mL Pouches)

FIZZMIXTM KIT – CUSTOMIZED EFFERVESCENT COMPOUNDING FORMULATIONS3

CONTACT US TODAY TO PLACE AN ORDER WWW.MEDISCA.COM 1.800.932.1039 | 1.800.665.6334 | 1300 786 392

DISCLAIMER : For use in prescription pharmacy compounding only, in accordance with applicable law. MEDISCA makes no warranty or representation regarding the use of this product or fitness for any particular purpose, and any such use is entirely the responsibility of the pharmacist in the exercise of his/her professional expertise and judgment. Accordingly, in no event will MEDISCA be liable for any damages from the use or misuse of the product. Purchaser’s sole remedy in the event of product defect or other damage, shall be the refund of the purchase price of the product.

GET STARTED TODAY!Grow your practice and competitive edge with MEDISCA’s comprehensive FizzMixTM Kit. We want to set you up for success as quickly as possible with all the necessary tools to elevate your compounding practice and surpass your patients’ expectations with our FizzMix Kit.

Additional items sold separately

Hardware

• 6588-01: Bins (PE), Sachet Filling, 2.5 mL

• 6591-01: Bins (PE), Sachet Filling, 5.0 mL

• 6587-01: Bins (PE), Sachet Filling, 7.5 mL

• 6589-01: Bins (PE), Sachet Filling, 10.0 mL

• 9813-01: Impulse Sealer (Small) 8“

• 7173-01: Mixer, Manual Inversina, 1.5 L

Flavors

• 2000: Apple

• 2851: Passion Fruit

• 2852: Raspberry

• 2853: Orange

• 2854: Mango

Product No.: 6586