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Figure 10.6
Structure of the
Neuromuscular Junction
Process Diagrams Step-by-Step
Copyright © 2007 by John Wiley & Sons, Inc.
1
Axon terminal
Axon terminal
Axon collateral ofsomatic motor neuron
Sarcolemma
Myofibril
ACh is releasedfrom synaptic vesicle
Junctional fold
Synaptic vesiclecontainingacetylcholine(ACh)
Sarcolemma
Synaptic cleft(space)
Motor end plate
Synaptic cleft(space)
(a) Neuromuscular junction
(b) Enlarged view of the neuromuscular junction
(c) Binding of acetylcholine to ACh receptors in the motor end plate
Synapticend bulb
Synapticend bulb
Neuromuscularjunction (NMJ)
Synaptic end bulb
Motor end plate
Nerve impulse
1
1
Axon terminal
Axon terminal
Axon collateral ofsomatic motor neuron
Sarcolemma
Myofibril
ACh is releasedfrom synaptic vesicle
ACh binds to Achreceptor
Junctional fold
Synaptic vesiclecontainingacetylcholine(ACh)
Sarcolemma
Synaptic cleft(space)
Motor end plate
Synaptic cleft(space)
(a) Neuromuscular junction
(b) Enlarged view of the neuromuscular junction
(c) Binding of acetylcholine to ACh receptors in the motor end plate
Synapticend bulb
Synapticend bulb
Neuromuscularjunction (NMJ)
Synaptic end bulb
Motor end plate
Nerve impulse
Na+
1
22
1
Axon terminal
Axon terminal
Axon collateral ofsomatic motor neuron
Sarcolemma
Myofibril
ACh is releasedfrom synaptic vesicle
ACh binds to Achreceptor
Junctional fold
Synaptic vesiclecontainingacetylcholine(ACh)
Sarcolemma
Synaptic cleft(space)
Motor end plate
Synaptic cleft(space)
(a) Neuromuscular junction
(b) Enlarged view of the neuromuscular junction
(c) Binding of acetylcholine to ACh receptors in the motor end plate
Synapticend bulb
Synapticend bulb
Neuromuscularjunction (NMJ)
Synaptic end bulb
Motor end plate
Nerve impulse
Muscle action potential is produced
Na+
1
2
3
2
1
Axon terminal
Axon terminal
Axon collateral ofsomatic motor neuron
Sarcolemma
Myofibril
ACh is releasedfrom synaptic vesicle
ACh binds to Achreceptor
Junctional fold
Synaptic vesiclecontainingacetylcholine(ACh)
Sarcolemma
Synaptic cleft(space)
Motor end plate
Synaptic cleft(space)
(a) Neuromuscular junction
(b) Enlarged view of the neuromuscular junction
(c) Binding of acetylcholine to ACh receptors in the motor end plate
Synapticend bulb
Synapticend bulb
Neuromuscularjunction (NMJ)
Synaptic end bulb
Motor end plate
Nerve impulse
Muscle action potential is produced
ACh is broken down
Na+
1
2
4
3
2