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www.du.ac.in Page 1
Title Prof./Dr./Mr./Ms. Dr.
First Name
Manu Last Name Agarwal Photograph
Designation Associate Professor
Department Botany
Address (Campus) Room No. 9, Department of Botany University of Delhi, Delhi 110007
(Residence) 168 Mukherjee Park II F Behind Subhash Nagar Pacific Mall New Delhi-‐110018
Phone No (Campus) 01127662609
(Residence)optional
Mobile
Fax
Email [email protected]
Web-‐Page
Education Subject Institution Year Details B.Sc. Rohilkhand University 1993 Subjects: Zoology, Botany,
Chemistry M.Sc. Goa University 1995 Subjects: Marine Biotechnology M.Phil University of Delhi 1997 Thesis topic: “High temperature
induced protein alterations associated with germination of seeds in rice, maize and wheat with emphasis on 104 and 90 kDa proteins.”
Ph.D. University of Delhi 1999 Thesis topic: “Molecular characterization of high and low molecular weight heat shock genes/proteins from rice (Oryza sativa L)”
Career Profile Organisation / Institution Designation Duration Role University of Arizona Tucson, USA Postdoctoral research
associate Sept 2002-‐Dec 2003
Research
University of California Riverside, USA
Postdoctoral research associate
Jan 2004-‐June 2007
Research
TERI University, India Assoc Professor July 2007-‐Jan 2008
Research and Postgraduate teaching
University of Delhi Reader Jan 2008-‐ Jan 2011
Research and Postgraduate teaching
University of Delhi Reader Jan 2011-‐present Research and Postgraduate teaching Research Interests / Specialization
University Faculty Details Page on DU Web-‐site
www.du.ac.in Page 2
My research interests are in understanding the gene regulation mechanisms in plants subjected to stressful environments. Our lab utilizes a combination of genomics and genetics approaches to decipher gene regulation at transcriptional, post-‐transcriptional, translational and post-‐translational levels. Of particular interest is discovery of novel stress regulated small RNAs from crop plants. Other projects in lab include biotechnological approaches to improve stress tolerance in crop plants and using reporter mutagenesis screens to isolate and implicate components in abiotic stress signaling pathways.
Teaching Experience ( Subjects/Courses Taught) Molecular Genetics, Recombinant DNA technology, Molecular and Cell Biology and Genomics.
Honors & Awards CSIR National Research Fellowship holder 1995-‐2000
Publications (LAST FIVE YEARS) Books / Monographs Year of Publication
Title Publisher Co-‐Author
In Indexed/ Peer Reviewed Journals Year of
Publication
Title Journal Co-‐Author
2012 Singh A, Mittal D, Lavania D, Agarwal M, Mishra RC, Grover A. OsHsfA2c and OsHsfB4b are involved in the transcriptional regulation of cytoplasmic OsClpB (Hsp100) gene in rice (Oryza sativa L.).
Bhardwaj AR, Pandey R, Agarwal M and
Katiyar-‐Agarwal S. Northern Blot Analysis for
Expression Profiling of mRNAs and Small
RNAs.
Cell, Stress and
Chaperones.
17(2):243-‐54
Methods in
molecular biology.
883:19-‐45
Singh A, Mittal D,
Lavania D, Mishra
RC, Grover A.
Bhardwaj AR,
Pandey R and
Katiyar-‐Agarwal
2011 Agarwal M, Singh A, Mittal D, Sahi C, Grover
A. Cycloheximide-‐mediated super-‐induction
of genes involves both native and foreign
transcripts in rice (Oryza sativa L.)
Plant Physiol
Biochem. 49(1):9-‐
12.
Singh A, Mittal D,
Sahi C, Grover A.
2011 Ji L, Liu X, Yan J, Wang W, Yumul RE, Kim YJ,
Dinh TT, Liu J, Cui X, Zheng B, Agarwal M, Liu
C, Cao X, Tang G, Chen X. ARGONAUTE10 and
ARGONAUTE1 Regulate the Termination of
Floral Stem Cells through Two MicroRNAs in
Arabidopsis.
PLoS Genetics.
7(3): e1001358.
Ji L, Liu X, Yan J,
Wang W, Yumul
RE, Kim YJ, Dinh
TT, Liu J, Cui X,
Zheng B, Liu C,
Cao X, Tang G,
www.du.ac.in Page 3
Chen X.
2010 Yu B, Bi L, Zhai J, Agarwal M, Li S, Wu Q, Ding
SW, Meyers BC, Vaucheret H, Chen X. siRNAs
compete with miRNAs for methylation by
HEN1 in Arabidopsis.
Nucleic Acids Res.
38(17):5844-‐50.
Yu B, Bi L, Zhai J, Li
S, Wu Q, Ding SW,
Meyers BC,
Vaucheret H, Chen
X.
2008 Yu B, Bi L, Zheng B, Ji L, Chevalier D, Agarwal
M, Ramachandran V, Li W, Lagrange T,
Walker JC, Chen X. The FHA domain proteins
DAWDLE in Arabidopsis and SNIP1 in humans
act in small RNA biogenesis.
PNAS, USA
105:10073-‐8
Yu B, Bi L, Zheng
B, Ji L, Chevalier D,
Ramachandran V,
Li W, Lagrange T,
Walker JC, Chen X.
2007 Sahi C*, Agarwal M*, Singh A and Grover A.
Molecular characterization of a novel isoform
of rice (Oryza sativa L) glycine rich RNA
binding protein and evidence for its
involvement in high temperature stress
response. (*-‐ equal contributions).
Plant Science 173:
144-‐155
Sahi C, Singh A
and Grover A
(2007).
Articles Vivek Raxwal, Surekha Katiyar-‐Agarwal and Manu Agarwal (2012). Structural and Functional Diversity of
Plant Heat Shock Factors. Plant Stress 6: 89-‐96. Global Science Books
Manu Agarwal and Jian-‐Kang Zhu (2005). Integration of abiotic stress signaling pathways: In Plant
abiotic stress Eds. Matt Jenks and Mike Hasegawa, Blackwell Publishers pgs: 215-‐237.
Agarwal M, Katiyar-‐Agarwal S and Grover A. Plant Hsp100 proteins: structure, function and regulation.
Plant Sci 163: 397-‐405.
Grover A, Aggarwal PK, Kapoor A, Katiyar-‐Agarwal S, Agarwal M and Chandramouli A. 2002. Addressing
abiotic stresses in agriculture through transgenic technology. Curr Sci 84(3): 355-‐367.
Agarwal M, Katiyar-‐Agarwal S, Sahi C, Gallie DR and Grover A. 2001. Arabidopsis thaliana Hsp100
proteins: kith and kin. Cell stress and Chaperones 6(3): 219-‐224.
Katiyar-‐Agarwal S, Agarwal M, Gallie DR and Grover A. 2001. Search for the cellular functions of plant
www.du.ac.in Page 4
Hsp100/Clp family proteins. Crit Rev Plant Sci 20(3): 277-‐295.
Grover A, Kapoor A, Katiyar-‐Agarwal S, Agarwal M, Sahi C, Jain P, Kotak S, Agrawal S, Dubey H. 2001.
Experimentations in biology of plant abiotic stress responses. Proc Indian Natn Sci Acad B67 (5): 189-‐
214.
Grover A, Kapoor A, Satya Lakshmi O, Agarwal S, Sahi C, Katiyar-‐Agarwal S, Agarwal M and Dubey H.
Understanding molecular alphabets of the plant abiotic stress responses. 2001. Curr Sci 80: 206-‐216.
Grover A, Agarwal M, Katiyar-‐Agarwal S, Sahi C and Agarwal S. 2000. Production of high temperature
tolerant transgenic plants through manipulation of photosynthetic membrane lipids. Curr Sci 79: 557-‐
559.
Grover A, A Kapoor, C Sahi, S Agarwal, S Katiyar-‐Agarwal, M Agarwal and H Dubey. 2000. Abiotic stress
responsive genes and promoters in plants. Proceedings Andhra Pradesh Netherlands project workshop
"Biotechnological interventions for abiotic stress management in rainfed crops", Central Research
Institute for Dryland Agriculture, Hyderabad, pp. 1-‐39.
Katiyar-‐Agarwal A, Agarwal M and Grover A. 1999. Emerging trends in agricultural biotechnology
research: use of abiotic stress-‐induced promoter to drive expression of a stress resistance gene in the
transgenic system leads to high level stress tolerance associated with minimal negative effects on
growth. Curr Sci 77: 1577-‐1579.
Conference Presentations
Total Publication Profile optional Books
In Indexed/ Peer Reviewed Journals 17
Articles 11
Conference Presentations
Public Service / University Service / Consulting Activity Departmental Administrative work, which include building maintenance and installation of Phosphorimager Infrastructure development and maintenance Ex-‐member for Bioinformatics Setup in the Department Other day-‐to-‐day activities for smooth functioning of the department.
www.du.ac.in Page 5
Professional Societies Memberships
Projects (Major Grants / Collaborations) 1) PI in DBT funded project “Development and stress-‐specific genomics of small non-‐coding RNAs from Brassica sps., rice and wheat Phase II ” 2) PI in DBT funded COE for the project “Transgenic approaches for frost tolerance in Brassica juncea” 3) Co-‐PI in DBT funded project “Profiling of small RNAs unique to Apomictic addition lines in Pennisetum glaucum through Subtractive small RNA library” Other Details Five registered Ph.D. Students
(Signature of Faculty Member) (Signature & Stamp of Head of the Department)