Faculty of Allied Medical Faculty of Allied Medical SciencesSciences

ParasitologyParasitology(MLPR-201)(MLPR-201)

fall 2013/2014fall 2013/2014

kingdom : Protista (Protozoa)kingdom : Protista (Protozoa)

Dr. Hamdy  Badie M. El-WakilProf. of Parasitology & Public Health .

Faculty of Allied Medical Sciences.Pharos University In Alexandria,Egypt

By the end of this lecture, students should understand the classification, pathogenicity, clinical importance and clinical features of kingdom : Protista (kingdom : Protista (Pathogenic Pathogenic Protozoa) .Protozoa) .

Hu

man

Para

sit

olo

gy

Medical

Helminthology

Medical

Protozoology

Medical

Arthropodology

• Class Nematoda• Class Trematoda• Class Cestoda• Class MetacanthocephalaClass Metacanthocephala

• Class Lobosea• Class Zoomastigophorea• Class Sporozoa• Class Ciliophora

• Class Insecta • Class Arachnida• Class Crustacea• Class Chilopoda

5

kingdom : Protista (Protozoa)kingdom : Protista (Protozoa)

Only a few of the many tens of thousands of protozoa species are pathogenic for humans

1- Intestinal:1- Intestinal: Entamoeba histolytica (Ameba).

Giardia lamblia (Flagellate).

Cryptosporidium parvum (Sporozoan).

2- Urogenital:2- Urogenital: Trichomonas vaginalis.

3- Blood and tissues:3- Blood and tissues:

Plasmodium species (Sporozoan).

Toxoplasma gondii (Sporozoan).

Trypanosoma species (Flagellate).

Leishmania species (Flagellate).

(I) Pathogenic protozoa:(I) Pathogenic protozoa:

1- Phylum: Sarcomastigophora: (a) Subphylum: Sarcodina e.g. Amoeba

(b)Subphylum: Mastigophora e.g. Trypansoma Digestive and genital tracts Blood and tissues.   2- Phylum: Ciliophora (Ciliates): Balantidium coli

Intestinal parasite of man.

3- Phylum: Apicomplexa: Class: Sporozoa: Asexual and sexual generations (All are parasitic). (e.g. Malaria).

Amebas : Move by extending cytoplasmic projections.

Flagellates : Move by rotating whip – like flagella.

Ciliates : Move by synchronous beating of hair – like cilia.

Sporozoa : Generally have non-motile adult forms.

8

ProtozoaProtozoa

9

A.A.

10

11

12

Intestinal InfectionsIntestinal Infections

There are three principal protozoal intestinal parasites: the ameba Entamoba histolytica, the flagellate, Giardia lamblia and several varieties of sporozoa, Cryptosporidium parvum. Each causes a dysentry which although similar, differs in the site of infection, the severity and secondary consequences.

13

14

15

16

Entamoeba sp. (causing amoebiasis)

17

18

Pathology (Invasion of the large intestine)Pathology (Invasion of the large intestine)

19

ComplicationsComplications

20

Entamoeba histolytica Entamoeba histolytica (causing amoebiasis)(causing amoebiasis)

21vulvitis

22

23

24

25

26

27

Life Cycle of Balantidium coliBalantidium coli

28

Complete the following sentences: Pathogenic protozoa could be intestinal Pathogenic protozoa could be intestinal

as……………….,……….. or………………. Like as……………….,……….. or………………. Like ……….and……………….or Blood and tissues, ……….and……………….or Blood and tissues, like……………………….,………………..and………….like……………………….,………………..and………….

Amebas : Move by………………while Flagellates Amebas : Move by………………while Flagellates

Move by…………………..Move by………………….. Entamoba histolytica, Giardia lamblia and, Entamoba histolytica, Giardia lamblia and,

Cryptosporidium parvum. Each causes a ………….Cryptosporidium parvum. Each causes a ………….

Group of students will be selected for an assignment topic ,one of the parasites that are studied in your course.

The following points should be covered in your assignment sheets:

(1) Classification Position:(2) Name of the parasite;(3)Description ( Morphological Characters in vivo): (4) Definitive (Final) Host:(5) Intermediate Host:(6) Mode Of Infection:(7) Infective Stage:-.(8) Habitat:- (9) Diagnostic Stage:- (10) Disease:- (11) life cycle

Schistosoma sppطه زغلول محمد خالد باسم

شابون مهدي رياض مهدي بسمه

شكري احمد محمد اشرف بسنت

احمد محمد علي حسن بسنت

النقيب القادر عبد صالح محمد محمود

حسن علي الفتاح عبد عادل مراد

محمود محمد السالم عبد محمد مروة

بريقع علي محمد مروه