Faculty details profile for IIU Web-site

Name Dr. Bubun Banerjee Photograph Designation Assistant Professor

Address Department of Chemistry, Indus International University, V.P.O-Bathu, Dist. Una, Himachal Pradesh, Pin Code- 174301, India

Phone No. 8582804332

E-mail bubun.banerjee@iiuedu.in, banerjeebubun@gmail.com

Educational Qualification Degree Institution University Year Branch

Ph.D Dept. of Chemistry,

Visva-Bharati (a central University)

Visva-Bharati (a central University)

2016 Organic Synthesis

M. Sc Ram Jas College, New Delhi

University of Delhi 2010 Organic Chemistry

B. Sc St. Xavier’s College,

Kolkata University of Calcutta 2008 Chemistry

(Hons.)

Qualified CSIR-UGC NET EXAMINATION held on June 2010

Title of the PhD thesis: “Development of some new organic methodologies with special emphasis on greener aspects” PhD supervisor: Prof. (Dr.) Goutam Brahmachari, Department of Chemistry, Siksha Bhavana, Visva Bharati University, Santiniketan, West Bengal, India. Teaching experience: Taking classes of B. Sc, M. Sc, and B. Tech students

Research Interests: Research work based on the fields of Organic Synthesis (Viz, synthetic methodologies, semi synthesis and total synthesis). Research Achievements: 1. Synthesis of densely functionalized 2-amino-3-cyano-4H-pyrans and pyran annulated heterocyclic scaffolds

Ref. ACS Sustainable Chem. Eng., 2014, 2, 411-422.

2. Sulfamic acid-catalyzed one-pot access of 3,3-bis(indol-3-yl)indolin-2-ones and 2,2-bis(indol-3-yl)acenaphthylen-1(2H)-one derivatives

2,2-Bis(indol-3-yl)acenaphthylen-1(2H)-one

3,3-Bis(indol-3-yl)indolin-2-ones

Indoles (2 equiv)

4 entries (yield: 89-93%)

isatins (1equiv)

23 entries (yield: 82-94%)

R1,R2 = H,H; F,H; Br,H; CH3O,H;

H,CH3; COOCH3,H

EtOH:H2O (1:1 v/v)

sulfamic acid(20 mol%)

N

R2

R1

N

O O

R4

R3

rt,2-7h

O

O

R3 ,R

4 =H,H;F,H;Br,H;

Cl,H; NO 2,H; H,CH 3

N

N

N

O

R2 R2

R1 R1

R3

R4

N N

OR1 R1

R2 R2

Acenaphthaquinone(1 equiv)

ORTEP View

Ref. ACS Sustainable Chem. Eng., 2014, 2, 2802-2812.

3. Sulfamic acid-catalyzed synthesis of bis(6-aminouracil-5-yl)methane derivatives

+

R H

OSulfamic acid

(20 mol%)

No column

chromatography

Room Temp.

Aq. EtOH

Recycle

22 entries

(up to 94% yield) CCDC 968994

N

N

O

NH2O

H3C

CH3 N

N

R

N

N

NH2O

H3C

O

CH3NH2O O

CH3

CH3

(1 equv.)

(2 equv.)

-H2O(second molecule)

ONH3SO3

NN

O

OCH3H3C

H2N

NN

RN

N

NH2

O

CH3

CH3

H2N

O

H3C

OCH3

O

RH

NN

O

OCH3H3C

H2N

OR

H H

NN

O

OCH3H3C

H2N

OR

H

N

N

OO

CH3

H3C

NH2

NH2SO3

H

NH3SO3

(first molecule)

(protontransfer)

H

NH3SO3NN

O

O

CH3H3C

HN

R(intermediate)

NH2 SO3 H

NN

O

O

CH3H3C

N

R

O3SH3N

Aq. EtOH

NH2SO

3H

-NH2SO3

H

Ref. Current Organocatalysis, 2016, 3, 125-132

4. NH4Cl-Catalyzed synthesis of 1,8-dioxo-octahydroxanthenes and N-aryl-1,8-dioxo-decahydroacridines

Ref. J. Chem. Res., 2014, 38, 745-750.

5. Synthesis of biologically relevant αααα-aminonitriles under solvent-free conditions at room temperature

Ref. Asian J. Org. Chem., 2012, 1, 251-258.

6. Sustainable one-pot synthesis of a wide array of fused O- and N-heterocycles catalyzed by trisodium citrate dihydrate under ambient conditions

EtOH : H2O

(1:1, v/v), rt

CN

CN

PQP

O O

P = CH2,Q = C(CH3)2

R1 = CH3,iPr, Ph, CH3COCH2

H2N

NC

R

O NNH

R1

R1

O

OEt

O

NH2-NH2.H2O

+

HN

N

O

R1

Insitu

generated

Trisodium citrate(10 mol%)

EtOH : H2O

(1:1, v/v), rt

(A total of 80 entrieswith 81-95% yield)

N

O

OR1

OR2

O

O

NC

H2N

HN

OR-CHO

N

O

O

Trisodium citrate(10 mol%)

N

O

O

O

NC

H2N

N

O

NNH

R1

O

NC

H2N

N

O

NNH

COOR5

NH2-NH2.H2O

+

HNNH

O

COOR5

COOR5R5OOC

H2N

NC

R

O NNH

COOEt

Insitu

generated

R1 = CH3,iPr, Ph,

CH2COCH3

R1

O

OR2

O

R3

R3

R3

R3

R3

R3

P = NCH3,Q = CO

R4R4

P = CH2,Q = CH2

QP

P

O

O

NC

H2N

O

OO

PQP

O O

R2 = CH3, C2H5

R4R4

R4

R5 = Me, Et

O

NC

H2N

O

O

O

R-CHO

O

OH

O

CH3O

NC

H2N

O

O

O

O

OH

O

QP

P

O

O

NC

H2N

N

O

R3R4

O

O

O

NC

H2N

HN

O

R3

O

NC

H2N

OHN

N

O

R1

NNH

R1

Insitu

generated

O

OH

O

Ref. Asian J. Org. Chem. 2016, 5, 271-286

List of Publications: 1. Goutam Brahmachari and Bubun Banerjee, Ceric ammonium nitrate (CAN): an efficient

and eco-friendly catalyst for the one-pot synthesis of alkyl/aryl/heteroaryl-substituted bis(6-aminouracil-5-yl)methanes at room temperature. RSC Adv., 2015, 5, 39263-39269.

2. Goutam Brahmachari and Bubun Banerjee, Facile and one-pot access to diverse and densely functionalized 2-amino-3-cyano-4H-pyrans and pyran-annulated heterocyclic scaffolds via an eco-friendly multicomponent reaction at room temperature using urea as a novel organo-catalyst. ACS Sustainable Chem. Eng., 2014, 2, 411-422.

3. Goutam Brahmachari and Bubun Banerjee, Facile and one-pot access of 3,3-bis(indol-3-yl)indolin-2-ones and 2,2-bis(indol-3-yl)acenaphthylen- 1(2H-one derivatives via an eco-friendly pseudo-multicomponent reaction at room temperature using sulfamic acid as an organo-catalyst. ACS Sustainable Chem. Eng., 2014, 2, 2802-2812.

4. Bubun Banerjee and Goutam Brahmachari, Ammonium chloride catalyzed one-pot multicomponent synthesis of 1,8-dioxo-octahydroxanthenes and N-aryl-1,8-dioxo decahydroacridines under solvent free condition. J. Chem. Res., 2014, 38, 745-750.

5. Goutam Brahmachari, Sujay Laskar and Bubun Banerjee, Eco-friendly, one-pot multicomponent synthesis of pyran annulated heterocyclic scaffolds at room temperature using ammonium or sodium formate as non-toxic catalyst. J. Heterocyclic Chem., 2014, 51, E303-E308.

6. Goutam Brahmachari and Bubun Banerjee, Facile synthesis of symmetrical bis(benzhydryl)ethers using p-toluenesulfonyl chloride under solvent-free conditions. Org. Med. Chem. Lett., 2013, 3, 1.

7. Goutam Brahmachari, Sajal Sarkar, Ranjan Ghosh, Soma Barman, Narayan C Mandal, Shyamal K. Jash, Bubun Banerjee, Rajiv Roy, Sunlight-induced rapid and efficient biogenic synthesis of silver nanoparticles using aqueous leaf extract of Ocimum sanctum Linn. with enhanced antibacterial activity. Org. Med. Chem. Lett., 2014, 4, 18.

8. Goutam Brahmachari and Bubun Banerjee, A comparison between catalyst-free and ZrOCl2·8H2O-catalyzed strecker reactions for the rapid and solvent-free one-pot synthesis of racemic �-aminonitrile derivatives. Asian J. Org. Chem., 2012, 1, 251-258.

9. Goutam Brahmachari and Bubun Banerjee, Facile and chemically sustainable one-pot synthesis of a wide array of fused O- and N-heterocycles catalyzed by trisodium citrate dihydrate under ambient conditions. Asian J. Org. Chem., 2016, 1, 271-286.

10. Goutam Brahmachari and Bubun Banerjee, Catalyst-free organic synthesis at room temperature in aqueous and non-aqueous media: An emerging field of green chemistry practice and sustainability. Current Green Chem., 2015, 2, 274-305.

11. Goutam Brahmachari and Bubun Banerjee, Sulfamic acid-catalyzed carbon-carbon and carbon-heteroatom bond forming reactions: An overview. Current Organocatalysis, 2016, 3, 93-124.

12. Bubun Banerjee, Vivek K. Gupta, Sumati Anthal, Rajni Kant and Goutam Brahmachari, Synthesis, spectroscopic characterization and X-ray analysis of symmetrical bis[bis-(4-chlorophenyl)-methyl] and bis[bis-(4-fluorophenyl)-methyl]ethers. Signpost Open Access J. Org. Biomol. Chem., 2013, 1, 23-32.

13. Sumati Anthal, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta, Trimethyl(triphenylmethoxy)silane. Acta Cryst., 2012, E68, o556.

14. Sumati Anthal, Goutam Brahmachari, Sujay Laskar, Bubun Banerjee, Rajni Kanta and Vivek K. Gupta, 2-Amino-7,7-dimethyl-5-oxo-4-(p-tolyl)- 5,6,7,8-tetrahydro-4H- chromene-3-carbonitrile. Acta Cryst., 2012, E68, o2592-o2593.

15. Naresh Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta, Crystal structure of 5,5′[(4-fluorophenyl)methylene]bis [6-amino-1,3-dimethyl pyrimidine-2,4(1H,3H)-dione]. Acta Cryst., 2014, E70, o1098-o1099.

16. Naresh Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta, Ethyl 6-amino-5-cyano-4-phenyl-2,4-dihydropyrano [2,3-c]pyrazole-3-carboxylate dimethyl sulphoxide monosolvate. Acta Cryst., 2014, E70, o795-o796.

17. Naresh Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta, 6-Amino-3-methyl-4-(3,4,5-trimethoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile. Acta Cryst., 2014, E70, o875-o876.

18. Sakshi Sharma, Sujay Laskar, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta, Crystal structure of 2-(4-nitrophenyl)-2-(phenylamino)propanenitrile and 2-(4-fluorophenylamino)-2-(4-nitrophenyl)propanenitrile. Crystallography Reports, 2014, 59, 1037-1041.

19. Suresh Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta, Synthesis, Characterization, and Crystal Structure of 2-Amino-5-oxo-4-phenyl-4,5- dihydropyrano[3,2-c]chromene-3-carbonitrile Crystallography Reports. 2015, 60, 1142-1146.

20. Suresh Sharma, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta, X-ray studies of 2-amino-5-oxo-4-propyl-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile. Crystallography Reports. 2015, 60, 865-868.

21. Suresh Sharma, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta, Synthesis, characterization and crystal structure of 2-amino-7-methyl-5-oxo-4-phenyl-4,5-dihydropyrano[3,2-c]pyran-3-carbonitrile. Crystallography Reports. 2015, 60, 1126-1130.

22. Suresh Sharma, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta. X-ray studies of 2-amino-4-(3-nitrophenyl)-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile and 2-amino-7,7-dimethyl-4-(4-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile. Crystallography Reports. 2015, 60, 1136-1141.

23. Naresh Sharma, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta. Crystal structure of 2-amino-7,7-dimethyl-5-oxo-4-(pyridin-4-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile hemihydrates. Crystallography Reports, 2015, 60, 1111-1115.

24. Sakshi Sharma, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta. Synthesis, characterization and crystal structure of 5,5"-difluoro-1H,1"H-[3,3':3',3"-terindol]-2'(1'H)-one. Crystallography Reports, 2016, 61, 225-229.

25. Suresh Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta, Structure of 2-amino-5-oxo-4-p-tolyl-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile. Eur. Chem. Bull., 2014, 3, 654-657.

26. Balbir Kumar, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta, Structure of 5'-chloro-5,5"-difluoro-1H,1"H-[3,3':3',3" -terindol]-2'(1'H)-one. Eur. Chem. Bull., 2015, 4, 177-180.

27. Suresh Sharma, Bubun Banerjee, Goutam Brahmachari, Rajni Kant and Vivek K. Gupta, X-ray studies of methyl 6-amino-5-cyano-2-methyl-4-(3-nitrophenyl)-4H-pyran-3- carboxylate. Eur. Chem. Bull., 2015, 4, 230-233.

28. Suresh Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta. X-ray studies of 2-amino-4-isopropyl-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile. Eur. Chem. Bull., 2015, 4, 368-371.

29. Sakshi Sharma, Goutam Brahmachari, Bubun Banerjee, Rajni Kant and Vivek K. Gupta. Synthesis, spectroscopic characterization, x-ray analysis of DMSO solvated 5'-chloro-1H,1"H-[3,3':3',3"-terindol]-2'(1'H)-one. Eur. Chem. Bull., 2015, 4, 389-392.

30. Balbir Kumar, Goutam Brahmachari, Bubun Banerjee, Khondekar Nurjamal, Rajni Kant and Vivek K. Gupta. Structure of 2-amino-4-(3-bromophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile. Eur. Chem. Bull., 2016, 5, 14-17.

31. Bubun Banerjee and Goutam Brahmachari, Room temperature metal-free synthesis of aryl/heteroaryl-substituted bis(6-aminouracil-5-yl)methanes using sulfamic acid (NH2SO3H) as an efficient and eco-friendly organo-catalyst. Current Organocatalysis, 2016, 3, 125-132.

32. Goutam Brahmachari, Bubun Banerjee, Balbir Kumar, Rajni Kant and Vivek K. Gupta, Synthesis, spectroscopic characterization and X-ray analysis of racemic 2-(4-chlorophenyl)- 2-(4-fluorophenylamino)acetonitrile. J. Ind. Chem. Soc., 2015, 92, 1473-1478.

33. Sakshi Sharma, Goutam Brahmachari, Bubun Banerjee, Khondekar Nurjamal, Abhishek Kumar, Ambrish Kumar Srivastava, Neeraj Misra, Sarvesh Kumar Pandey, Rajnikant and Vivek K. Gupta, Synthesis, spectroscopic characterization and crystallographic behavior of a biologically relevant novel indole-fused heterocyclic compound d Experimental and theoretical (DFT) studies. J. Mol. Structure, 2016, 1118, 344-355.

Pin-Points [Feature articles]

1. Bubun Banerjee, Per-6-amino-β-cyclodextrin (per-6-ABCD) (Pin-point 1), Signpost

Open Access J. Org. Biomol. Chem., 2015, 3, 28-33. 2. Bubun Banerjee, Zn[(L)proline]2 (Pin-point 4), Signpost Open Access J. Org. Biomol.

Chem., 2015, 3, 80-86. 3. Bubun Banerjee, Baker’s yeast (Pin-point 5), Signpost Open Access J. Org. Biomol.

Chem., 2015, 3, 87-91.

List of Publications as a corresponding author: 1. Bubun Banerjee, Recent developments on ultrasound assisted catalyst-free organic

synthesis. Ultrason. Sonochem. 2016, in press, DOI: 10.1016/j.ultsonch.2016.09.023. 2. Bubun Banerjee, Recent developments on ultrasound-assisted one-pot multicomponent

synthesis of biologically relevant heterocycles. Ultrason. Sonochem. 2016, in press, DOI: 10.1016/j.ultsonch.2016.10.010.

3. Bubun Banerjee,. Sc(OTf)3 catalyzed carbon-carbon and carbon-heteroatom bond forming reactions: A review. Arkivoc. 2016, Accepted, MS. No. 16-9868LR.

Conference attended:

1. Goutam Brahmachari and Bubun Banerjee, Development of a novel and efficient protocol for the synthesis of symmetrical Bis(diarylmethyl)ethers using copper chloride as reusable catalyst under solvent-free conditions. “Proceedings of the Acharya Prafulla Chandra Ray Memorial Symposium on Chemistry Today (2011) and Celebration of the International Year of Chemistry” on August 2-3, 2011, Organized by The Indian Chemical Society, 92, Acharya Prafulla Chandra Road, Kolkata-700009.

2. Bubun Banerjee and Goutam Brahmachari, Rapid and solvent-free one-pot synthesis of α-aminonitriles at room temperature: comparison between catalyzed and catalyst-free conditions. In “INDO-US WORKSHOP on Green Chemistry for Environments & Sustainable Development” on 11-13th March, 2012, Organized by Department of Chemistry, Hemwati Nandan Bahuguna Garhwal (a Central University), Srinagar, Uttarakhand, India-246174.

3. Bubun Banerjee and Goutam Brahmachari, Development of an efficient MCR-protocol for the facile one-pot synthesis of biologically relevant 4H-pyran-annulated heterocyclic scaffolds at room temperature. In “International Conference on Global Opportunities for Latest Developments in Chemistry and Technology (GOLD-CT-2014)” on February 06-08, 2014 organized by School of Chemical Sciences, North Maharashtra University, Jalgaon-425001. (Got best poster award)

4. Bubun Banerjee and Goutam Brahmachari, Facile access to biologically relevant 4H-pyran-annulated heterocyclic scaffolds via one-pot multicomponent reaction at room temperature. In national seminar on “Recent Advances in Chemistry” on 9th March 2014, organized by Department of Chemistry, Visva-Bharati, Santiniketan. WB-731235.

Research Experience: 5 years of research experience and can operate NMR (400 MHz Bruker), IR, UV machine.