explain the relationship between mutation, cell cycle, and uncontrolled cell growth potentially resulting in cancer.

Jessica SantosMcArthur High School

Cell Cycle Stages•The life of a cell is regulated by numerous checkpoints and proteins

•A mutation in a protein that is meant to either SLOW or STOP the cell cycle can cause a cell to

LOSE CONTROL

CANCER•Is known as UNCONTROLLED cell division•It happens when REGULATION of the cell cycle has broken down

•CANCER CELLS:•Divide more often than do healthy cells•May form disorganized clumps called TUMORS•Comes from normal cells that have suffered damage to the genes that help make proteins involved in Cell Cycle Regulation

A. one that sped up the cell cycleB. one that slowed down the cell cycleC. one that acted as a growth-promoting moleculeD. one that responded to growth-promoting molecules

Cancer is often characterized by tumors. Which would most likely trigger the formation of a tumor?

A. a parasite that both lived and reproduced within the human body

B. a change in the DNA sequence of a gene that codes for skin coloration

C. a bacterial infection that caused inflammation and swelling in body tissues

D. a mutation in a gene that codes for a protein regulating cell