Do something amazing, help save lives!

New You!New Year,

New Challenge,

Set yourself a challenge this year...

Every year over six thousand people in the UK have to start renal replacement therapy because their kidneys have failed. It’s reported by the NHS that one thousand people unfortunately die while waiting for an organ - 90% of people on the waiting list desperately need a kidney.

Samantha Lamb set London Bridges Walk as a goal last year in her bid to lose three stone so she could donate a kidney to her husband, Andy, in time to save his life.

The start of 2009 couldn’t have been harder but Samantha was determined to take her body mass index of 42.8 to below 35 so doctors would allow her to have the life-saving transplant operation.

Samantha started her diet by swapping burger and chips for planned meals of complex carbohydrates such as brown rice, potatoes and bread. She also signed-up for the gym and worked with a personal trainer, setting herself milestones along the way, including the London Bridges Walk.

Samantha said: “When you meet somebody who understands you in every single way and loves you for you, you are going to do everything you can to save that person. The kids need their dad and I need a husband. I’m 37, far too young to be a widow.”

Fast forward to 2010 and we’re delighted to report that the transplant operation was a huge success and both Andy and Samantha are doing extremely well.

Danny Carnegie has Down’s syndrome which dramatically affects his fitness and ability to exercise. Despite this, he has raised an amazing £850.

Zainab Khan defied the odds by not only surviving a brain haemorrhage in 1991 and having a kidney transplant in 2007 but completed the London Bridges Walk 2009, raising £1,200, and then won four medals in the British Transplant Games 2009!

2

Samantha in 2009 before her weight loss

Samantha after her weight loss

FACT:

Samantha lost weight to save her husband’s life and used London Bridges Walk as her goal

Zainab is so lucky to be alive Danny ran three miles with the support of his wonderful sister

Brian King stopped smoking and went to the gym 2-3 times a week to ensure he was healthy enough for the transplant operation.

He ran the Bupa Great North Run and raised £1,200.

Brian got fit to save his daughter’s life

Ben Spink (23) had a successful kidney transplant in April 2009 which has transformed his life. To celebrate, he has persuaded his fellow Lincolnshire Young Farmers and friends to join him in a Case IH Puma 210 tractor to drive from Land’s End to John O’Groats to raise vital funds for the charity.

If that wasn’t tough enough, they are also attempting to climb the three biggest peaks in the UK along the way, Snowdon, Scafell Pike and Ben Nevis.

“I am wishing for a new kidney this Christmas” Jasmine, aged 7

A patient’s story

Set yourself a challenge this year... 3

Damon cycled 150 miles because he doesn’t want anybody else to have to experience his gruelling 24-hour kidney operationDamon Bullimore has witnessed first-hand how investment into kidney research actually saved his two children from not having to have the same horrific operation he had to endure.

Damon said: “I’m a great fan of Kidney Research UK, so much to the point that myself and my business partner, Rick Palmer, went to the French Alps to challenge ourselves to a 150 mile bike ride over two days. We need to continually raise as much needed funds as possible to help more children, like mine.”

Right, Damon and Rick enjoying the French Alps

“We’re so proud of Daddy and Rick...’” Opposite, Damon’s wife Jacqueline with children, Olivia and Mason Bullimore

David ran the Bupa Great North Run with no kidneys!Dialysis patient, David Rand, suffers from Polycystic Kidney Disease (PKD) and was diagnosed with high blood pressure in 1998 after graduating as a Chemical Engineer.

David, who raised £700, said: “I had both my kidneys removed because they were very large and were restricting the space for a kidney transplant. I received a kidney in 2008 but it failed and had to be removed within 24 hours. Throughout all of this I have kept active and as fit as I possibly can.”

This year David’s thinking about running the Virgin London Marathon. “Not until he gets a kidney!” said his extremely proud Dad.

Andrew felt running the London Marathon was nothing compared to what his sister has had to cope withAndrew Holmes ran the 2009 Flora London Marathon as a 40th Birthday challenge, to do something for his sister who has renal failure and also to raise money for research.

He said: “I thought that meeting the £1,400 golden bond would be harder than the running. Wrong! People have been so generous and it was great to be part of the Charity’s team.”

Amy Leigh is walking Britain’s coastline to help find a cure“My brother Dean sadly died in 2005 after a long, painful battle against kidney disease. Unfortunately for Dean there was nothing that could be done to save him – he was just too ill to undergo a kidney transplant and his regular dialysis treatment was no longer effective.”

45,000 people in the UK are being treated for Kidney failureFACT: Kidney disease can affect people of any ageFACT:

“We’re very thankful for all the work that has been done on Kidney Research and how it has transformed people’s lives. May this work go from strength to strength.”

A patient’s story

Bupa Great Manchester RunStarting in Manchester City centre, the Bupa Great Manchester Run will take you over a 10k course around this great City. Feel the atmosphere and hear the cheers from supporters as the route takes you past some of the city’s most historic sights.

Does the idea of cycling through tranquil rural villages and the peaceful countryside roads of France and England appeal to you?

Well why not sign up to join us on our fabulous London to Paris Cycle Ride! This event is an absolute delight to take part in and places fill up very quickly.

The cycle ride leads you through the tranquil rural villages and the peaceful countryside roads of England and France. You will be cycling through historic towns and cities, with plenty of opportunities to take breaks during the day to experience local hospitality and to sample the French cuisine. Everything is taken care of on this hassle-free event and you will be given all the support and care you need before and during the trip.

The event is an amazing experience and by the time you head home you will have not only have helped fund research to save lives, but also made fabulous memories and gained some lifelong friends from other team members!

30 JUNE – 4 JULY 2010

LONDON2PARISCYCLING CHALLENGE

KIDNEY RESEARCH UK’s

Events calendar 2010 Plan your challenges for the year ahead... we have something for everyone!4

Bupa Great South RunThis flat, fast course attracts elite athletes from around the world as well as celebrities and fun runners alike, and gives you the perfect opportunity to try for your personal best!

19th September 2010

Edinburgh Marathon

Renowned as the UK’s fastest marathon, the 26.2 mile course takes you from this beautiful City and out to finish at Musselburgh Racecourse.

London Marathon 2011 The Virgin London Marathon is the most famous and prestigious marathon in the world and all who compete go home with a strong sense of satisfaction and accomplishment.

Cycle Challenge Running EventsBupa Great North RunJoin an assorted mix of elite athletes, celebrities and charity runners competing in the world’s biggest and most famous half marathon! The 13.1 mile route starts in the heart of Newcastle and finishes in South Shields.

Ben Nevis ChallengeBen Nevis, the highest mountain in Britain, stands majestically at 1,344 meters (4,409 feet) amongst the hills and Monroes of the Scottish Highlands. This adventure is an amazing experience which offers the opportunity to walk up one of the most spectacular and picturesque mountains in Great Britain and is also a fantastic weekend away!

Walking Events15th - 17th Oct 2010

Be Inspired!

Watch coverage from our 2009 climb on our

website at: www. kidneyresearchuk.

org/events

Helen Leslie Smith, a Renal Nurse, took part in the London to Paris cycle challenge in 2009.

“I became really fit, made some life-long friends and cycled through some beautiful countryside.

“The organisation was brilliant with great support in order to keep you on track with the others.

“It was also great to be able to indulge in lots of lovely French cuisine because I was able to work it off the next day.”

Sign up today to register for any of these events or for further information visit www.kidneyresearchuk.org/events email events@kidneyresearch.org or call 08456 12 12 26

16th May 2010

24th October 2010

23rd May 2010

Pict

ure

cour

tesy

of

Bup

a G

reat

Run

/

Pete

r Lan

gdow

n

London 2 Paris Cycle 30th June - 4th July 2010

ChinaFor those wishing to mix the challenge of the lifetime with an adventure through a country steeped in history, grandeur and natural beauty, then this is the event for you! Walk along the magnificent Great Wall and come away with some amazing memories.

PeruTrek through the untouched Lares region of Peru, over high mountain passes, green valleys, tranquil mountain lakes and breathtaking views of snowcapped Andean mountains all whilst experiencing Peruvian life first hand.

Events calendar 2010 Plan your challenges for the year ahead... we have something for everyone!

KilimanjaroThis breathtaking trip will guide you up the tranquil Machame route where you will trek through lush deep forests, home to spectacular wildlife, stretching up to moorland and onwards towards glaciers before reaching the Uhuru Peak. This will be one of the most challenging and rewarding experiences of your life: be part of this truly magnificent journey.

Overseas Challenges ParachuteJumps

London Bridges Walk 2010 We invite you, your family and your friends to join us as we walk a route which will take you over eleven of London’s most famous bridges. Feel the camaraderie as you join kidney patients, their families and friends, as well as our other dedicated supporters all wearing their purple t-shirts with pride!

Anyone can enter, young or old. The route will start and finish at Boules area, Battersea Park, where we will have an exclusive hospitality area for all to enjoy. Register online at www.kidneyresearchuk.org/londonbridgeswalk

13th June 2010

5

British Gas Great North SwimThe British Gas Great North Swim is a one-mile open water swim in Windermere, England’s largest Lake. It has become a world renowned event, attracting swimmers of all abilities from elite to novice.

Abseils

Swim NEW EVENT FOR 2010LIMITED PLACES AVAILABLE.

Sign up today to register for any of these events or for further information visit www.kidneyresearchuk.org/events email events@kidneyresearch.org or call 08456 12 12 26

24th Sept - 3rd Oct 2010 April 2011 (dates tbc)

8th - 17th Oct 2010 May 2011 (dates tbc)

17th - 26th Sept 2010 15th - 24th Oct 2010

4th - 5th Sept 2010

Canonteign Abseil

At 220ft, Canonteign Falls at Christow, near Exeter is the highest waterfall in England, set amongst what visitors describe as one of the most idyllic places on earth.

1st & 2nd May 2010

Guy’s Abseil

Guy’s Tower stands at 450ft and is the ultimate abseil, offering breathtaking views across London and an adrenaline rush like never before! Descend down the exterior of the famous hospital tower to feel your feet touch the ground and the sense of satisfaction of achieving your own personal goal!

27th & 28th March 2010

Pict

ure

cour

tesy

of

Bup

a G

reat

Run

/

Pete

r Lan

gdow

n

Right now, over three million people in the UK are at risk of chronic kidney disease. Please help us to help them.FACT:

The adrenaline kicks in...

the most amazing feeling...

...what a fantastic experience!

thumbs up, all ok...

Various dates and venues available

We appreciate everything you do!The Charity’s Liz and Lin (left) welcome back runners at the Bupa Great North Run before they had their well deserved massage.

How do I fundraise? It’s easier than you think!6

Uncontrolled, or poorly controlled, high blood pressure can cause chronic kidney failure.FACT:FACT: Diabetes is the single largest cause of kidney failure.

“I asked for donations instead of birthday presents and raised £330.” Lydia Langley

“I raised £600 from organising a Race Night” Abby Tombs

Here are a few tried and tested ideasTo raise £100...

Cook dinner for a few friends, ask them to pay!

Or, ask your local school to hold a non-uniform day

Or, persuade a friend to shave their head/legs/sit in a bath of custard!

Car boot sale profits – ask friends and family to donate items

We’ll help you find things you’re happy doing to raise life-saving funds.

Give your local Kidney Research UK fundraising expert a call

Set up your own fundraising pageRegister for a fundraising account with Kidney Research UK, which will be the online home of all your donation gathering for us. Your account comes with a personalisable profile, showing all the efforts you have made to raise money.

Go online and visit www.kidneyresearchuk.org to set up your page today!

Or, arrange a Friday night three-legged pub crawl

“I was feeling a bit depressed but then on 15th January 2000 I got the magical call from Western Infirmary, Glasgow, “We have a kidney for you!”.Since then I have walked the Forth Road Bridge and the Golden Gate Bridge, raising £1,000.”

Our regional community fundraisers are here to give you help and support to hit your fundraising targets.

For details of your local community fundraiser visit www.kidneyresearchuk.org

Or, ask friends, family and work colleagues for sponsorship money

“I raised £300 from selling cakes” Adam Langrick

A patient’s story

Or, hold a karaoke in your local pub for a percentage of the drink sales

Or, organise a quiz night with a raffle

Host a summer BBQ for friends

To raise £150...

To raise £200...

Don’t forget to ask your employer to match the amount you raise!

We also know how to party!

7

£27 One hour of vital research by a research fellow.

£50 Printing costs for a campaign to educate approximately 100 people about the early signs of kidney problems.

£675 A 68 year old man has ‘end stage renal failure’ and relies on a kidney dialysis machine to stay alive. He also has a wide range of health issues including diabetes, hypertension and epilepsy. He received a Kidney Patient Support Grant to buy an adjustamatic chair which costs £675. The deterioration in his health has caused mobility problems and the gentleman finds it difficult transferring from sitting to standing. This chair will help improve his quality of life through mobility.

£1,000 Would provide the plastic ware required each year for a research study looking at the potential of stem cells to repair kidney damage in Alports Syndrome.

£3,000 Running costs of the Kidney Health Information Service for one month.

£10,000 Provides 2-years of consumables for a young researcher who is carrying out research to see if it is possible through a different approach to prevent the high levels of blood phosphate in kidney patients.

£54,094 Will support the second year’s research of a ‘future research expert’ who is testing if stopping a process in the body may lead to less transplant rejection and a better outcome for patients.

£90,000 Budget allocated to support kidney patients through the Kidney Patient Support Grants Scheme, during 2008/2009.

£319,578 Senior Researcher Fellow who is supported for 5 years to look at specific molecules involved in the filtering part of the kidney.

Award-winning researchDr Michael Robson from King’s College London, was the only UK winner in an international award and has been awarded a grant by Kidney Research UK for two years’ work that will explore the disease mechanisms by which our own immune system attacks the kidney to cause inflammation and kidney failure.

Where is my money spent? Other ways the money is spent includes:

We are currently researching for a transplanted kidney to be ‘for life’ rather than an average of 14 years.FACT:

Getting closer to a cureOver the last eight years the Charity has invested more than £1 million into studying the Macrophage. We believe we can programme these immune cells to repair kidney scarring, which often causes kidney failure.

Dr David Kluth, pictured left, and his research group from the University of Edinburgh have completed the final stage of this study, but it now needs to progress to clinical trials, which will cost millions.

Improving health on dialysis or with kidney diseaseDr Joanne Marks, at the Royal Free, London, is researching to see if it is possible to prevent the complications of phosphate overload in chronic kidney failure via the gut (intestines).

Improving transplant successDr Matthew Welberry Smith, from Leeds, is looking to identify new protein biomarkers in blood and/or urine that could help us diagnose problems with transplanted kidneys earlier. His work is joint funded with the Medical Research Council.

The charity produces educational DVDs on kidney disease for patientsFACT:

“My husband, Mike, was on dialysis for six years before a very successful transplant which lasted for nearly 20 years until his death (not connected with his kidney). Not everyone is so lucky to receive such a gift. Keep up the good work with your research into kidney failure”.

A patient’s story

We invest in research that focuses on the prevention, treatment and management of kidney disease.We have currently invested £9 million into research and support on average 13 research projects each year. Below are few of these projects. To find out more about all our researchers and projects, please visit www.kidneyresearchuk.org

Medical breakthrough – a UK firstThe Charity funded the first verified research project by Dr Xu to prove Chinese complementary medicines indeed have anti-scarring activities, supporting that they can work alongside conventional medicine in fighting against renal scarring – the common cause of chronic kidney failure. The outcomes of this study can have a massive impact on patients affected by chronic kidney disease, bringing us closer to a cure for many people.

Help us save lives by supporting kidney research

Please enter your name and address below

Title Mr Mrs Miss Other

Name

Address

Postcode

Telephone

Email

Please complete and return this form to Kidney Research UK, FREEPOST ANG 3465, Peterborough PE1 1BR

Please send me a registration form and more information on:

China Trek 2010 Kilimanjaro Trek 2010

Peru Trek 2010 Ben Nevis Challenge 2010

Parachute Jumping London to Paris Cycle Ride 2010

Bupa Great North Run 2010 Bupa Great South Run 2010

Bupa Great Manchester Run 2010 Edinburgh Marathon 2010

London Bridges Walk 2010 British Gas Great North Swim 2010

Canonteign Abseil 2010 Guy’s Abseil 2010

Would you like to receive our events ‘What’s On’ newsletter by email?Bringing you all the latest news and event information straight to your inbox, our new email newsletter will have all the details you need to register for all our challenge events.

To receive a copy you can either visit our website and sign up online or complete this form and send it back to us at our Freepost address. Registration for your favourite event is only a few clicks away!

YES, please sign me up for the ‘What’s On’ email newsletter

Sign up now!

Kidney Research UK would like to write to you with further information relating to our activities. If you do not wish to receive such information please tick this box.

For more information, visitwww.kidneyresearchuk.org or email events@kidneyresearchuk.org or call 08456 12 12 26

The 2010 Photo CompetitionPlease upload your events pictures via flickr.com to help share your experience, inspire others and allow us to gather inspirational pictures to use in our future literature.

To help encourage you, we will organise a prize for the best picture at the end of the year. We also used the winning picture (shown above) on the front of our annual review.

So, whenever you are at one of our events, supporter receptions, cathedral services or just out training with a Kidney Research UK T-shirt on – send us those photos!

We rely heavily on the goodwill of our participants and supporters, and by taking part in this annual photo competition will mean you are helping Kidney Research UK to make people aware of the life saving research we do.

The clock is ticking – we need more funds to help save more lives – Please help us.

Registered Office : Kidney Research UK, Kings Chambers, Priestgate, Peterborough PE1 1FG

Tel: 0845 070 7601 Fax: 01733 704699

Please visit our website at www.kidneyresearchuk.org and help us fund research to save lives.

Donation Line 0800 783 2973Registered Charity No. 252892 Registered Scottish Charity No. SC039245. Registered Company No. 905963 Registered in England and Scotland.

Jacqui Mould won last year’s

photo competition with her picture ‘River of Dreams’.

River of Dreams

EV01

Why not participate in one of our events as a team...