Ethics at the Beginning of Life

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    Ethics at the beginning of life

    AbortionEmbryonic stem cell

    IVF

    Preimplantation screening

    Children with serious healthproblems

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    Cornerstone of biomedical ethics

    Autonomyrespecting an individuals rights of freedom and liberty to make

    changes that affect his or her life

    Beneficenceacting so as to benefi t others

    Non-maleficenceavoiding harming people unnecessarily

    Justicetreating people truthfully and fairly

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    LEGAL

    SCIENTIFIC ETHICAL

    RELIGIOUS

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    ABORTION

    Basic facts in human development

    Fertilization Implantation

    Embryonic period

    Fetal period

    The baby is ready for life outside the womb

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    ABORTION

    What is abortion? Is the termination of pregnancy by removal or expulsion

    from the uterus of a fetus or embryo before viability What are the reasons for abortion?

    Economic cost

    Family planning

    Heath

    Rape incest

    Age

    Societys moralism

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    ABORTION

    What are types of abortion?

    Natural/ spontaneous/ accidental abortion Direct/ intentional abortion

    Therapeutic abortion

    Eugenic/ selective abortion/ abortion on fetal

    indication Indirect abortion

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    Viewpoints on ABORTION

    CONSERVATIVE Abortion is never permissible except it is required to save the

    pregnant womans life

    Murder?!

    LIBERAL Abortion is always permissible, whatever the state of fetal

    development is

    Women have freedom to control their own reproductive capacities

    Fetus is neither an individual nor a person, but only a tissue in

    womans uterus. It possesses no rights and no moral status MODERATE

    Abortion is morally permissible up to certain stage of fetaldevelopment and some limited sets of situations.

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    In my opinion

    Taking away the potential of life is morally

    wrong Removing a baby is totally different from

    removing a tissue in the body. The baby has

    potential to grow and contribute to society

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    EMBRYONIC STEM CELL

    Stem cell Cell that has ability to continuously divide and

    differentiate into other kinds of cell

    Stem cell type Totipotent: cells from early (1-3 days) embryos

    Pluripotent: cells from blastocyst (5-14 days)

    Multipotent: differentiated cell can form a numberof other tissues, from fetal tissue, cord blood,adult stem cell

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    First mammal cloned from adult cells

    1996

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    What are we waiting for?

    Replaceable tissues/ organs

    Repair of defective cell types Delivery of genetic therapies

    Delivery of chemotherapeutics agents

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    Possible points of contention

    Source of cells

    Source of funding Autonomy or freedom

    Respect for life

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    Legal consideration of embryonic stell

    cell research

    Reproductive cloning: not allowed

    Therapeutic cloning: allowed Research on embryo: allowed

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    Ethic principles for embryonic stem

    cell research

    Principle of Respect Embryo is human life which should not be damaged without

    reason Because of potential benefit in treating human diseases,research should be allowed and supported.

    Principle of Informed consent (autonomy)

    Principle of Safety and utility (non-malfeasance)

    Principle of Non-commercialization (justice) Tissues and cells should be donated Buying and selling of gametes, embryos and fetal tissues

    should not be allowed.

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    IVF

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    IVF

    Process by which an egg is fertilized by sperm

    outside the body

    A major treatment for infertility when other methods

    of assisted reproductive technology have failed

    4 basic steps

    1. Superovulation

    2. Egg collection

    3. In vitro fertilisation

    4. Embryo transfer

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    Fertility treament

    Married couple? Single women? Same sex

    couple? Too old?

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    We are doctors trying to do the best for

    our patients

    Playing god?

    Should embryonic research be banned?

    Dealing with creating human life

    Unnatural_ Some religious organization disapprove of theprocedure

    Have to come with government rules and guidelines

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    Complication

    Multiple births

    Birth defects

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    Indication

    Sex linked genetic disorders Hemophilia

    Duchenne muscular dystrophy Chromosomal disorders

    Downs syndrome ( Trisomy 21)

    Single gene diseases ( using PCR) Thalassemia

    Older women doing IVF Screen embryos foraneuploidy

    Recurrent pregnancy loss because of chromosomalanomalies

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    Preimplantation screening

    Note a cure

    Designed baby

    To prevent life suffering

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    Children with serious health problem

    Child with limited viability or lethal syndrome

    or life-threatening anomaly Challenging heal care provider

    Ethical and legal dilemmas

    Effective communication between health

    care team and parents is essential

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    Children with serious health problem

    The baby can not make a decision by himself

    Autonomy: end of life decision is made based on

    parents moral and religious belief Ensure that parents have a comprehensive

    understanding of existing condition

    Must respect parent right to make medical decisions

    for their own child Be aware of our legal options, when we believe

    parents are not making medical decision in the bestinterest of newborn