EQUINE HEALTH STUDIES PROGRAM - lsu.edu for lameness, gastrointestinal disease, endocrine disease and respiratory disease, ... equine health and welfare. Sincerely, Joel Baines, VMD,

2018 Equine Research ReportScientific studies conducted to help advance equine health and well-being

EQUINE HEALTH STUDIES PROGRAM

LETTER FROM OUR DEAN

The LSU School of Veterinary Medicine is pleased to once again

present the 2018 Equine Health Studies Program (EHSP) Equine

Research Report, which covers scientific and scholarly activities

of the program from 2015 through 2017. The EHSP continues

to focus on the health, well-being and performance of horses

by delivering state-of-the-art research and clinical services that

benefit the horse-owning public. As the new Dean of the School of

Veterinary Medicine, it is an honor for me to be a part of this premier

equine program. I am impressed with the comprehensive research

performed by the faculty, graduate students, house officers and staff

within this program, as evidenced by the contents of this report.

Since its inception in 2005, the EHSP has been translating research

into practical solutions for our broad-based constituents and clients

in addition to delivering clinical services, education and community

outreach to referring veterinarians and clients.

The EHSP continues to make significant contributions to our understanding of the complex mechanisms of horses in health and

disease. The EHSP collaborates with other universities, industry and foundations to discover new treatment and preventative

measures for lameness, gastrointestinal disease, endocrine disease and respiratory disease, which collectively result in a significant

yearly loss of revenue to the equine industry. More specifically, EHSP faculty scientists are actively studying a number of common

diseases, including osteoarthritis, laminitis, long bone fracture repair, gastric and colonic ulcer disease, Equine Cushing’s disease,

and inflammatory and allergic airway disease (summer pasture associated obstructive pulmonary disease). Recently the EHSP has

become a Good Laboratory Practices (GLP) laboratory and completed a study which was submitted to the FDA.

The EHSP continues to build and maintain strong relationships and community engagements with Louisiana stakeholders so that

it can respond to the needs of horses and horse owners. In the aftermath of the Great Flood of Baton Rouge 2016 and Hurricane

Harvey, the EHSP and the LSU SVM, in concert with the Louisiana State Animal Response Team and Texas A&M University College of

Veterinary Medicine, helped horses and other large animals in need by supplying personnel for search and rescue, triage of injured

animals, and clinical and surgical care. The EHSP has been and continues to be on-alert to respond to the needs of horses and is a

model for emergency preparedness for other veterinary institutions. Additionally, the EHSP continues to provide strong leadership

and the latest information to horse owners through its continued involvement with referring veterinarians, the Louisiana State

Racing Commission, the Louisiana Equine Council, the Louisiana Thoroughbred Breeders Association, the Louisiana Horse Rescue

Association and many others.

The program has always been about the people and horses and we are blessed by strong relationships with the equine community. I

could not be more proud of the emergence and productivity of our EHSP as it continues to benefit horses throughout the world. I am

always humbled by the dedication of our faculty and staff and their continued commitment to the mission of the EHSP and the LSU

SVM. It is truly a nationally and internationally recognized program that has put the LSU School of Veterinary Medicine out in front in

equine health and welfare.

Sincerely,

Joel Baines, VMD, PhD

Dean, School of Veterinary Medicine, Louisiana State University

Professor, Department of Pathobiological Sciences

The LSU School of Veterinary Medicine continues to promote the

highest level of support for equine health and welfare through its

commitment to equine research and service. The equine industry

is an integral part of the Louisiana livestock community, including

the racing and performance, breeding and pleasure industries.

Our Equine Health Studies Program is the basis for the research

effort that investigates and provides up-to-date and pertinent

information for educating students and extending service to the

public.

Our faculty continue to participate in quality meaningful research

funded through intramural support from the EHSP and extra-

mural support from granting institutions and industry. We are

much appreciative of the National Institutes of Health, USDA,

Equine Health Appropriations from the State of Louisiana, the

Grayson Jockey Club Research Foundation, Elanco Animal

Health, Boehringer Ingelheim Animal Health, Zinpro Corporation,

Centaur Corporation, Seabuck Equine, LLC, SmartPill Corporation,

Pall Corporation, Purina Animal Health, Darling Ingredients, Inc.

(Sonac), Randlab, Kindred Bioscience, Inc. and other entities

that supplied funding for the EHSP research program. The

faculty contributing to the EHSP are to be commended for their

concerted efforts to ensure that equine health remains one of the

top priorities of the LSU SVM.

Sincerely,

Rhonda Cardin, AB, PhD

Associate Dean for Research and Advanced Studies

Professor, Department of Pathobiological Sciences

LETTER FROM OUR ASSOCIATE DEAN FOR RESEARCH AND ADVANCED STUDIES

LETTER FROM OUR DIRECTOR

As Director of the Equine Health Studies Program (EHSP), it is my pleasure to

present the 2018 EHSP Research Report from the LSU School of Veterinary

Medicine. This research report documents contributions by numerous faculty

and staff in the program. The EHSP team remains committed to the health,

well-being and performance of horses through veterinary research, education

and clinical and public service, and I congratulate contributors to the program.

The EHSP team continues to produce high quality biomedical research and

address horse health and welfare and disseminate that information to the

local, state, regional and worldwide stockholders. The EHSP biomedical

research team has diverse research interests with one major goal: to improve

the health and welfare of the horse. Investigators represented in this report

contributed information in the areas of equine surgery, gastrointestinal disease

(colitis and gastric ulcer disease), laminitis, reproduction, respiratory disease

and lameness. Each study in this report benefits the horse and the equine

industry by identifying essential mechanisms of disease, ground-breaking new

treatments, essential techniques in reproduction, and essential information to

prevent diseases. Many of the studies in this report were and continue to be

presented at local, regional, national and international meetings, including the

American Association of Equine Practitioners (AAEP), the American College of Veterinary Surgery (ACVS), the American College of

Veterinary Internal Medicine annual forum (ACVIM), the Colic Research Symposium, the Veterinary Orthopedic Society (VOS), the

EPM Society, Havemeyer Equine Endocrinology Workshop, the Havemeyer Laminitis Workshop, the Applied Equine Nutrition and

Training Conference, the International Equine Infectious Disease Conference, and the American Society of Animal Science. EHSP

researchers continue to be sought-after board members to review grants, present at state, regional, national and international

meetings and asked to present keynote speeches.

The biomedical research outlined in this report and state-of-the-art facilities on campus are the result of continued support from

the Louisiana Governor’s Biotechnology Initiative Grants Program, Louisiana Board of Regents Enhancement Grants Program and a

statutory dedication from the Louisiana racetrack slot machine tax revenues. The State funding provides researchers with technical

support and intramural funds to generate pilot data that leads to extramural funding from the Grayson Jockey Club Research, Morris

Animal and the Pennington Biomedical Research Foundations, National Wetlands Research Center, the Bureau of Land Management,

and industry partners Boehringer Ingelheim Vetmedica, Elanco Animal Health, SmartPak® Equine, LLC, Zinpro Corporation, Darling

Ingredients (Sonac), The High Bush Blueberry Council and Purina Animal Health, among others. Furthermore, we owe our deepest

gratitude to the horses that participate in these studies. The research findings presented in this report would not have been possible

without the availability and use of horses. All biomedical research on animals at LSU is conducted under Federal Guidelines for the

Humane Care and Use of Animals and approved by the Institutional Animal Care and Use Committee (IACUC). These horses are

valued members of our program and are treated with kindness and dignity.

LSU SCHOOL OF VETERINARY MEDICINE ADMINISTRATION

Joel D. Baines, VMD, PhDDean and Dr. Kenneth F. Burns Chair in Veterinary Medicine

Rhonda Cardin, PhDAssociate Dean for Research and Advanced Studies

Lorrie Gaschen, DVM, Dr.med.vet., Dr.habil., PhD, DECVDIAssociate Dean for Diversity and Faculty Affairs

Joseph Taboada, DVM, DACVIMAssociate Dean for Veterinary Education and Student Affairs

Ernie Tanoos, MPAAssistant Dean for Finance and Administrative Services

Frank Andrews, DVM, MS, DACVIMDirector of the Equine Health Studies Program

Mark Mitchell, DVM, PhD (LSU SVM 2001), DECZMDirector of the LSU Veterinary Teaching Hospital

Tracy Nye Evans, MPASenior Director of Development

Thomas RooneyDirector of Strategic Communications

The Equine Research Report is published by the Louisiana State University, School of Veterinary Medicine, Baton Rouge, LA 70803. Please send comments to Ginger Guttner, MMC, APR, communications manager, at [email protected], or Julie Thomas, MMC, public relations coordinator, at [email protected].

Phone: (225) 578-9500

facebook.com/LSU SVM

facebook.com/LSUequine

@LSUVetMed

instagram.com/LSUVetMed

LinkedIn: LSU School of Veterinary Medicine

lsu.edu/vetmed

The faculty and staff of the EHSP are proud to be a part of

this world-class program and look forward to the continued

participation in the biomedical research program as it moves

forward.

As part of the EHSP team, I am committed to furthering the

health, well-being and performance of horses everywhere

regardless of the breed or use. Also, with continued support

from the horse industry and the State of Louisiana, we can

further promote and establish the EHSP at the LSU SVM as

the premier equine biomedical program in the southern region

and the world.

Sincerely,

Frank M. Andrews, DVM, MS, DACVIM (LAIM)

LVMA Equine Committee Professor and Director

Equine Health Studies Program

Our Mission: The LSU Equine Health Studies Program will become a premier equine biomedical center in the 21st century through leading-edge research of equine diseases, contemporary instruction of professional veterinary students and veterinarians in advanced studies programs, and enhanced continuing education of the horse-owning public and private equine practitioners, with the ultimate goal of providing state-of-the-art diagnostic and therapeutic capabilities for critically ill and injured horses, and optimal clinical service to horsemen in Louisiana and the surrounding region.

TABLE OF CONTENTS

FACULTY ..................................................................................................................................................... 4

GRADUATE PROGRAM ............................................................................................................................12

PUBLICATIONS, ABSTRACTS AND PROCEEDINGS ............................................................................13

GRANTS .................................................................................................................................................... 43

HONORS AND AWARDS ......................................................................................................................... 53

FACILITIES AND EQUIPMENT ................................................................................................................ 57

LAMINITIS ................................................................................................................................................. 64

Assessment of Digital Venograms in Non-laminitic Horses .............................................................64

Use of Laser Capture Microdissection for the Assessment of Equine Laminar Basal Epithelial Cell Signaling in the Early Stages of Laminitis .....................................................................................65

STEM CELLS ............................................................................................................................................. 67

Optimized Adult Equine Multipotent Stromal Cell Osteogenesis with Customized Scaffolds and Perfusion Bioreactor Culture ............................................................................................................67

Isolation and Characterization of Equine Hoof Stem Cells...............................................................69

GASTROINTESTINAL DISEASE .............................................................................................................. 72

Effects of Metronidazole and Flunixin Meglumine on Equine Right Dorsal Colonic Mucosa .. 72

Acupuncture and Therapeutic Massage Treatment and the Attenuation of Salivary Cortisol Levels in the Domestic Horse .................................................................................................................. 74

The EHSP is part of the LSU School of Veterinary Medicine, which is one of only 30 veterinary schools in the U.S. and the only one in Louisiana. The EHSP is supported with funds provided by the Louisiana State University School of Veterinary Medicine, the State of Louisiana and contributions from private donors.

The LSU School of Veterinary Medicine: We teach. We heal. We discover. We protect.

TABLE OF CONTENTS

The Effects of Purina Outlast Gastric Supplement on Equine Gastric Health Parameters ....... 76

Alterations in Equine Gastric pH by Purina Outlast Gastric Supplement ...................................... 78

Effects of Hydrolyzed Collagen on Equine Gastric Ulcers Scores and Gastric Juice pH in Horses ............................................................................................................................................................80

HOSPITAL MANAGEMENT ..................................................................................................................... 84

Elimination of the Use Of Rubber Stall Mats for Effective Intervention of Nosocomial Salmonella Enterica Spp. Infection in a Veterinary Teaching Hospital .........................................84

SURGERY .................................................................................................................................................. 86

Assessment of Tuber Coxae Bone Biopsy in the Standing Horse .................................................86

Influence of Clodronate on Bone Density and Bone Formation in Young Horses .....................88

Influence of Tiludronate on Bone Density and Bone Formation in Young Horses ....................89

THERIOGENOLOGY ..................................................................................................................................91

Preeclamptic Mouse Model: Investigation of the Embryo-Uterine Interactions that Will Improve Mare-Foal Outcomes ..................................................................................................................91

DEVELOPMENT ........................................................................................................................................ 94

4

FACULTY

Frank M. Andrews, DVM, MS, DACVIM, LVMA Equine Committee Professor and Director of the Equine Health Studies Program, Veterinary Clinical Sciences

Dr. Andrews received his DVM and MS from Washington State University in 1983. He completed one year in private practice at

Associated Veterinary Clinics, Inc. in Walla Walla, Wash., and completed an internal medicine residency in 1988 at The Ohio State

University College of Veterinary Medicine. Dr. Andrews became a Diplomate of the American College of Veterinary Internal Medicine

in 1989 and was on the faculty at the University of Tennessee College of Veterinary Medicine from 1988-2008. His research focuses

on investigating treatment and prevention of gastric ulcer disease, gastric emptying and gastrointestinal motility, and treatment of

pituitary par intermedia dysfunction (Equine Cushing’s Disease).

Chance Armstrong, DVM, MS, DACT, Assistant Professor of Food Animal Health Management, Veterinary Clinical Sciences

Dr. Armstrong received his DVM in 2010 and his MS in 2016 from Auburn University. He also completed his theriogenology residency

at Auburn in 2015. He is a Diplomate of the American College of Theriogenologists. His research focuses on infertility of cattle with

a particular study of Trichomoniasis. Dr. Armstrong was also recognized as a 40 under 40 professional in 2014 by Vance Publishing,

which is a list of the most influential people in agriculture. He joined the faculty in 2015.

Renee T. Carter, DVM (LSU SVM 2000), DACVO, Assistant Professor of Ophthalmology, Veterinary Clinical Sciences

Dr. Carter received her DVM from the LSU SVM in 2000 and completed a rotating internship in small animal medicine and surgery

at the LSU SVM in 2001. She completed a four-year comparative ophthalmology residency and fellowship at the University of

Madison-Wisconsin in 2006 and returned to LSU as an assistant professor. Dr. Carter became a Diplomate of the American College

of Veterinary Ophthalmologists in 2007 and her research focuses on corneal wound healing disorders and the role of leptospirosis in

the pathogenesis of equine recurrent uveitis.

Ann Chapman, DVM (LSU SVM 2001), MS, DACVIM, Assistant Professor of Equine Medicine, Veterinary Clinical Sciences

Dr. Chapman was born and raised in Harrisburg, Penn. She received her BA in biology from Gettysburg College in 1990 and worked

in laboratory research in both government and private sectors. She received her DVM from the LSU SVM in 2001. After working in

private practice for one year, she began her combination equine internal medicine residency/graduate program at the LSU SVM

in 2002. Dr. Chapman completed her residency in 2005 and became a Diplomate of the American College of Veterinary Internal

Medicine. She received an MS in 2006 from the LSU SVM. She performs mobile equine medicine consultation throughout Louisiana

and equine ambulatory medicine to the Baton Rouge community. Her research interests include endocrine diseases, pars intermedia

pituitary dysfunction (PPID), equine cardiology, and infectious disease, especially Salmonella detection and prevention. Dr. Chapman

is also section chief of the Equine Ambulatory Service, which provides general specialty services to Baton Rouge, the region and the

State of Louisiana.

Shafiqul Chowdhury, DVM, MS, PhD, Professor, Pathobiological Sciences

Dr. Chowdhury received his DVM and MS degrees from Bangladesh Agricultural University (Bangladesh) and a PhD from the Goethe

Institute (Germany). He completed a post-doctoral fellowship in the Department of Microbiology at the University of Texas Health

Sciences Center in Houston, Texas. Dr. Chowdhury was a research scientist at Bayer Animal Health and was on the faculty at Kansas

State University College of Veterinary Medicine for 18 years before coming to LSU in 2008. His research interests include gene

characterization and vaccine development for Equine Herpes Virus 1 and Bovine Herpes Virus 1. He recently completed a USDA

grant and works closely with industry.

5

FACULTY

Elizabeth Coffman, DVM, MS, DACT, Instructor of Theriogenology, Veterinary Clinical Sciences

Dr. Coffman received her BS in 2005 and her DVM in 2009, both from the University of Tennessee. She received her MS from the

Ohio State University in 2013. Dr. Coffman is a Diplomate of the American College of Theriogenologists.She joined the faculty in

2016. Her research interests include equine reproduction and the uterine environment.

Jeanette Cremer, DVM, Dr.med.vet., DACVAA, Assistant Professor of Anesthesiology, Veterinary Clinical Sciences

Dr. Cremer received her DVM in 2003 and her Dr.med.vet. in 2005, both from Ludwig Maximilians University (Germany). She is a

Diplomate of the American College of Veterinary Anesthesia and Analgesia. Dr. Cremer completed her anesthesia residency at the

University of Georgia in 2011. She joined the faculty of the LSU SVM in 2014. Dr. Cremer’s research interests are in the evaluation of

learning competencies, validation of teaching methods, influence of computer based learning, and analgesic techniques.

Anderson da Cunha, DVM, MS, DACVAA, Associate Professor of Anesthesiology, Veterinary Clinical Sciences

Dr. da Cunha is Associate Professor and chief of the anesthesiology service for the Veterinary Teaching Hospital. He received his

DVM from Federal University of Parana in 2000 and his MS from Federal University of Santa Maria (Brazil) in 2002. He completed his

residency in anesthesiology at North Carolina State University in 2006, and he is a Diplomate of the American College of Veterinary

Anesthesia and Analgesia.

Chiara De Caro Carella, DVM, MS, Assistant Professor of Anesthesiology, Veterinary Clinical Sciences

Dr. De Caro Carella is an assistant professor of veterinary anesthesiology in the Department of Veterinary Clinical Sciences. She joined the

faculty on July 26, 2016. She received her DVM from the Università degli Studi di Messina (Italy) in 2008 and her MS from Oregon State

University in 2016; she completed her residency at Oregon State University in 2016 as well. Dr. De Caro Carella’s teaching interests are in

teaching acid-base physiology and diagnostic approaches, and her research focus is in hemodynamic monitoring under anesthesia, and

anesthetic techniques in swine to improve their overall welfare.

Levant Dirikolu, PhD, Professor, Comparative Biomedical Sciences

Dr. Dirikolu, professor in Comparative Biomedical Sciences (CBS) and director of the Equine Medication Surveillance Laboratory, joined the

faculty in January 2016. He received his DVM from Ankara University (Turkey) in 1992, his MVSc and his PhD, both from the University of

Kentucky in 2001. He completed a post-doctoral fellowship in veterinary pharamcology from the University of Kentucky in 2002.

Susan C. Eades, DVM (LSU SVM 1982), PhD, DACVIM, Professor of Equine Medicine, Veterinary Clinical Sciences

Dr. Eades received her DVM in 1982 from the LSU SVM and then completed an internship in large animal medicine and surgery and

a residency in large animal internal medicine at the University of Pennsylvania’s New Bolton Center. She then completed a PhD in

veterinary physiology at the University of Georgia. Her doctoral studies concentrated on intestinal vascular and nonvascular smooth

muscle physiology and pharmacology. Upon completion of her PhD, Dr. Eades began as an assistant professor of large animal

medicine at the University of Georgia College of Veterinary Medicine, where she remained through 1997. She returned to LSU in

1998 as an associate professor of equine medicine. Dr. Eades’ clinical interests include equine internal medicine; however, she has

a special interest in cardiology and ultrasound. Her research interests include intestinal disease and laminitis. Dr. Eades is currently

Department Head of Veterinary Clinical Sciences at Texas A&M University, College of Veterinary Medicine, College Station, Texas.

6

FACULTY

Bruce E. Eilts, Professor Emeritus of Theriogenology, Veterinary Clinical Sciences

Dr. Eilts is originally from the Minneapolis/St. Paul area in Minnesota. He attended the University of Minnesota as a pre-veterinary

medicine student and obtained a BS in veterinary science in 1975 and his DVM in 1977, both from the University of Minnesota. He

was in private practice for one year before returning to the University of Minnesota to obtain an MS in theriogenology in 1982. After

two and a half years in a private practice in southern California, he came to the LSU SVM as an assistant professor in 1984. He

became board certified in the American College of Theriogenologists in 1986, and his main clinical and research interests are in

basic reproduction management in the horse.

Jon Fletcher, DVM (LSU SVM 2005), DACVIM, Assistant Professor of Companion Animal Medicine, Veterinary Clinical Sciences

Dr. Fletcher received his DVM from the LSU SVM in 2005. He completed a small animal medicine and surgery rotating internship

at Auburn University before returning to LSU for his small animal internal medicine residency, which he completed in 2008. He

started an internal medicine practice in a private specialty hospital, where he remained for four years before returning to the LSU

SVM to join the faculty in 2012. Dr. Fletcher’s clinical interests include canine and feline endocrinology. He is the section head of

the Veterinary Endocrinology Laboratory and his research interests include diabetes mellitus, obesity and endocrine diagnostic

techniques.

Joseph Francis, BVSc, MVSc, PhD, Professor, Comparative Biomedical Sciences

Dr. Francis is a professorin the Department of Comparative Biomedical Sciences. He joined the faculty in 2003. Dr. Francis received

his BVSc in 1990 and his MVSc in 1994, both from the Madras Veterinary College in India. He received his PhD from Kansas State

University in 1999. His research focuses on the brain mechanisms regulating cardiovascular function, specifically the understanding

of the central nervous system interactions of cytokines renin-angiotensinaldosterone system, in heart failure. He’s also conducting

research on the benefits of blueberries and the effects of exercise.

Lorrie Gaschen, DVM, PhD, DECVDI, Professor of Diagnostic Imaging, Veterinary Clinical Sciences

Dr. Gaschen received her BS and DVM degrees from the University of Florida in 1985 and 1990, respectively. She received her PhD

from the University of Utrecht (Netherlands) in 2001. She is a Diplomate of the European College of Veterinary Diagnostic Imaging.

She joined the faculty at LSU in 2006. Dr. Gaschen’s research interests are in vascular imaging and ultrasound of the gastrointestinal

tract and pancreas, and MRI.

L. Abbigail Granger, DVM, MS, DACVR, Associate Professor of Diagnostic Imaging, Veterinary Clinical Sciences

Dr. Granger received her DVM from the University of Tennessee and completed a radiology residency. She is a Diplomate in the

American College of Veterinary Radiology. Her teaching interests include radiographic interpretation, ultrasound performance and

interpretation (basic, intermediate, and expert), and research methods. Her research interests include functional CT, thoracic CT

with emphasis on airways and interstitial disease, ultrasound in endocrine diseases, and correlation of ultrasound with pathological

findings. Dr. Granger is also the service chief for the LSU SVM Diagnostic Imaging Service.

Samithamby Jeyaseelan, DVM, PhD, Professor, Pathobiological Sciences

Dr. Jeyaseelan received his DVM degree from the University of Peradeniya (Sri Lanka) in 1992. He received his PhD in pulmonary

immunology from the University of Minnesota College of Veterinary Medicine in 2001. He completed his first post-doctoral training at

Yale University in pulmonary immunology in 2003 and his second post-doctoral training at National Jewish Health/Colorado Health

7

FACULTY

Sciences Center in lung biology in 2004, where he was also on the faculty from 2004-07. In addition to being a professor in PBS,

Dr. Jeyaseelan is also the director of the Lung Biology Laboratory. His research focuses on investigating the mechanisms underlying

lung inflammation and host defense in response to bacterial pathogens. Dr. Jeyaseelan has published more than 40 original articles

and more than 12 review articles. He serves as an associate editor of the Journal of Immunology, academic editor of PLoS One and

serves on the editorial boards of Clinical and Vaccine Immunology and Infection and Immunity. Dr. Jeyaseelan’s research is funded

by the National Institutes of Health and Flight Attendant Medical Research Institute.

Jill R. Johnson, DVM, MS, DACVIM, DABVP, Professor Emeritus of Equine Medicine, Veterinary Clinical Sciences

Dr. Johnson is a native of South Dakota and received her DVM from the University of Minnesota, where she also received her MS

degree in veterinary surgery and radiology. She joined the faculty of the LSU SVM in 1977. She is a Diplomate in both the American

College of Veterinary Internal Medicine and the American Board of Veterinary Practitioners (Equine Practice). Her past research

activities have centered on immunogenetics and immunology, methods of quantifying exercise training using the global positioning

system (GPS) and development of tissue culture models to study diseases. Her current research involves the spatial-temporal study

of hospital-acquired infections in the large animal hospital.

Ronald Koh, DVM, MS, Certified Acupuncture (CVA) and Canine Rehabilitation (CCRP), Assistant Professor, Veterinary Clinical Sciences

Dr. Koh received his DVM degree in 2006 from National Chung Hsing University College of Veterinary Medicine in Taiwan. He

completed a specialty internship in acupuncture in 2010 and received his Master’s degree in 2012 from University of Florida College

of Veterinary Medicine. Dr. Koh also gained certifications in acupuncture (CVA), Chinese herbal medicine (CVCH), and food therapy

(CVFT) through the Chi Institute, as well as Canine Rehabilitation (CCRP) through University of Tennessee College of Veterinary

Medicine. His clinical interests include TCVM and integrative medicine for pain management, neurological disorders, geriatric

conditions, and palliative and hospice care. Currently, Dr. Koh is an assistant professor and the section chief of the Integrative

Medicine Service at the Louisiana State University School of Veterinary Medicine. He has authored several articles on acupuncture,

rehabilitation and integrative medicine for publications in the United States and China. He has also been invited to provide lectures

and trainings on traditional Chinese veterinary medicine, integrative medicine and rehabilitation for veterinary schools, conferences,

and general public events in the United States, China, Russia, and Indonesia. Teaching interests include Integrative Medicine,

Acupuncture, Rehabilitation, Nutraceuticals, and Herbal Medicine. Research interests include acupuncture and physical therapy for

pain management, spinal injury, and post-surgery.

Britta Leise, DVM (LSU SVM 2002), MS, PhD, DACVS, Assistant Professor of Equine Surgery, Veterinary Clinical Sciences

Dr. Leise received her undergraduate degree from Virginia Tech in animal sciences and from there went to Louisiana State University

where she received a Master’s degree in equine reproductive endocrinology. In 2002, she graduated from Louisiana State University

School of Veterinary Medicine. She then completed an internship at the University of Georgia in large animal surgery and medicine.

Dr. Leise returned to Baton Rouge where she completed a residency in equine surgery and became a Diplomate of the American

College of Veterinary Surgeons in 2008. She was a clinical instructor in equine emergency and critical care at The Ohio State

University from 2007 until 2010, where she completed her PhD in Comparative and Veterinary Medicine with a focus on the role

of inflammation and the epithelial cell in equine laminitis. From there Dr. Leise became faculty at Colorado State University from

2011-2015 as an assistant professor of equine surgery and lameness. She returned to LSU in October 2015 as assistant professor of

equine surgery. Her research interest includes equine laminitis, wound healing and inflammatory conditions in the horse.

8

FACULTY

Mandi J. Lopez, DVM, MS, PhD, DACVS, Professor, Veterinary Clinical Sciences

From the Pacific Northwest, Dr. Lopez received her BS from Humboldt State University in Arcata, Calif., and received her DVM from the

University of California, Davis. She completed a food animal internship at Kansas State University prior to going to the University of

Wisconsin, where she completed a residency in large animal surgery and obtained MS and PhD degrees. She then did a post-doctoral

fellowship in applied biomechanics. Her areas of interest are comparative orthopedic research and surgery. Dr. Lopez is a Diplomate of

the American College of Veterinary Surgeons and holds several patents for biomedical devices and has expertise in both applied and

basic research. She came to LSU in 2004 and directs the Laboratory of Equine and Comparative Orthopedic Research (LECOR).

Aliya Magee, DVM (LSU SVM 2009), MS, DACVIM (Cardiology), Assistant Professor, Veterinary Clinical Sciences

Dr. Magee received her DVM from Louisiana State University School of Veterinary Medicine in 2009 and MS from Purdue University

School of Veterinary Medicine in 2013. She completed a Cardiology residency at Purdue University and is board certified in the

American College of Veterinary Internal Medicine, Cardiology. Her clinical and research interests include comparative cardiac disease.

Charles T. “Chuck” McCauley, DVM, MS, DABVP, DACVS, Assistant Professor of Equine Surgery, Veterinary Clinical Sciences

Dr. McCauley joined the equine faculty at the LSU SVM in 2006. Prior to that, Dr. McCauley was employed in a busy private referral

practice in northeast Texas. He received his DVM from Texas A&M University and completed an internship and residency in food animal

medicine and surgery at Oklahoma State University. In addition, Dr. McCauley completed a residency in large animal surgery (equine

emphasis) at Purdue University. He is a Diplomate of both the American Board of Veterinary Practitioners (Food Animal Practice) and

the American College of Veterinary Surgeons (Large Animal Surgery).

Rebecca S. McConnico, DVM (LSU SVM 1987), PhD, DACVIM, Professor of Equine Medicine, Veterinary Clinical Sciences

Dr. McConnico is originally from north central Ohio but received her DVM in 1987 from the LSU SVM. She received her PhD from

and completed a clinical residency in large animal internal medicine at North Carolina State University. She is a Diplomate of the

American College of Veterinary Internal Medicine. Dr. McConnico’s clinical interests include equine critical care and internal medicine.

She is also a certified veterinary acupuncturist. The long term goals of Dr. McConnico’s research collaborations are elucidating

the pathophysiologic mechanisms associated with intestinal diseases in horses and determining the link between these diseases

and other related abnormalities (e.g., laminitis, endotoxemia, myositis), with the broader intention of preventing, attenuating and

determining effective treatment modalities for these life-threatening conditions. Additionally, Dr. McConnico is integrally involved in

the development of the LSU SVM’s disaster preparedness and response program, which provides training and disaster response

in partnership with other LSU units, non-government groups, and state and federal government entities. Dr. McConnico is currently

Professor of Animal Science at Louisiana Technical University in Rustin, La.

Mustajab Mirza, DVM, MS, DACVS, Assistant Professor of Equine Surgery, Veterinary Clinical Sciences

Dr. Mirza received his DVM from the College of Veterinary Sciences Lahore affiliated with the University of Agriculture (Pakistan) in

1992. He completed his surgery residency and received his MS degree from the LSU SVM in 1998. Dr. Mirza is board certified in the

American College of Veterinary Surgery. Dr. Mirza’s primary clinical interests include repair of long bone fractures and pathogenesis of

colics in equids, laminitis, ophthalmology and advanced wound healing. He primarily provides after-hours emergency equine services

for the LSU Veterinary Teaching Hospital. Dr. Mirza’s research interests are in long bone fractures, performance limitations, advanced

therapeutics for osteoarthritis and gastrointestinal disease in horses.

9

FACULTY

Colin F. Mitchell, BVMS, MS, DACVS, Associate Professor of Equine Surgery, Veterinary Clinical Sciences

Originally from Perth, Scotland, Dr. Mitchell received his veterinary medical degree from the University of Edinburgh and completed an

internship at the University of Prince Edward Island prior to entering a combined three-year equine surgery residency and MS graduate

program at the University of Minnesota, which he completed in 2004. He then remained on the hospital staff at the University of

Minnesota, where he worked as the equine emergency clinician/surgeon until 2005, when he joined the faculty at the LSU SVM. He is

a Diplomate of the American College of Veterinary Surgeons, and his clinical interests include orthopedic, laparoscopic and respiratory

surgery. His research interests include orthopedic implants and laminitis and pharmaceutical treatment of navicular disease.

Dale L. Paccamonti, DVM, MS, DACT, Professor and Head, Veterinary Clinical Sciences

Dr. Paccamonti, originally from Kankakee, Ill., received his DVM from Michigan State University in 1981. After four years in a mixed

practice in Chestertown, Md., he pursued advanced training at the University of Florida, where he completed a residency in

theriogenology and received his MS degree in 1988. Dr. Paccamonti is a Diplomate in the American College of Theriogenologists.

He joined the faculty at the LSU SVM in 1988, where he is head of the Department of Veterinary Clinical Sciences and a professor of

theriogenology. His primary research interests include the study of infertility in mares, assisted reproduction techniques in horses,

factors affecting sperm motility in stallions, semen cryopreservation in stallions, and the process of fetal maturation and parturition in

mares. He also collaborates in reproductive research in other domestic species. He shares responsibility for clinical theriogenology

cases in all species presented to the LSU Veterinary Teaching Hospital.

Daniel B. Paulsen, DVM, MS, PhD, DACVP, Professor, Pathobiological Sciences

Dr. Paulsen received his DVM in 1977 and his MS in 1978, both from Kansas State University. In 1989, he received his PhD from

Oklahoma State University. Dr. Paulsen’s major research interests are in bovine respiratory disease with emphasis on Mannheimia

haemolytica, Pasteurella multocida, infectious bovine rhinotracheitis and bovine respiratory coronavirus; pathogenesis, bacterial

genetics, respiratory immunity and vaccinology; toxicologic pathology associated with inhaled toxins and effects of inhaled substances

on the pathogenesis of asthma; and application of immunohistochemical techniques in equine respiratory disease and laminitis. In

addition to being a professor in PBS, Dr. Paulsen is the director of the Louisiana Animal Disease Diagnostic Laboratory.

Carlos Pinto, DVM, PhD, DACT, Associate Professor of Theriogenology, Veterinary Clinical Sciences

Dr. Pinto received his DVM from Sao Paulo State University (Brazil) in 1986 and his PhD from the LSU School of Veterinary Medicine in

2001. He is a Diplomate of the American College of Theriogenologists. Dr. Pinto’s clinical interests are in comparative theriogenology

and assisted reproduction in equine, bovine and canine species. He joined the faculty in 2013 and his primary research interests

include artificial insemination and in vitro fertilization.

Cherie Pucheu-Haston, DVM (LSU SVM 1992), PhD, DACVD, Associate Professor of Dermatology, Veterinary Clinical Sciences

Dr. Pucheu-Haston received her DVM in 1992 from the LSU School of Veterinary Medicine and completed an internship in small

animal medicine and surgery at LSU in 1993. She received her residency training in veterinary dermatology at North Carolina State

University and is a Diplomate of the American College of Veterinary Dermatology. She worked as a specialist in private practice for

seven years, then returned to NCSU in 2002 to pursue advanced graduate training. She received her PhD in immunology (with a minor

in biotechnology) from NCSU in 2006. She completed three years as a post-doctoral research associate in the Immunotoxicology

Branch of the U.S. Environmental Protection Agency, as a grantee from the University of North Carolina-Chapel Hill. Dr. Pucheu-Haston

returned to LSU as a faculty member in 2011. Her research interests include identification of factors involved in the development and

perpetuation of atopic dermatitis, the relationships between allergic skin diseases and hypersensitivity in other organ systems (asthma,

gastrointestinal disease) and the identification of genomic or proteomic biomarkers of allergic sensitization.

10

FACULTY AND STAFF

Patricia Queiroz-Williams, DVM, MS, Associate Professor of Veterinary Anesthesiology, Veterinary Clinical Sciences

Dr. Queiroz-Williams joined the faculty of the LSU SVM in 2007. She received her DVM from the Universidade Federal de Minas

Gerais (Brazil) in 1996 and her MS from the Universidade Estadual Paulista School of Medicine (Brazil) in 2002. She also completed

a residency and her MS in anesthesiology at the Universidade Estadual Paulista (Brazil). Her research interests include inhalational

MAC studies; Pulse Pressure Variation and Stroke Volume Variation monitoring in colic horses; pain management and its assessment

in different species; anesthetic drugs’ pharmacodynamic/pharmacokinetic.

Nathalie Rademacher, Med.Vet., DACVR, DECVDI, Associate Professor of Diagnostic Imaging, Veterinary Clinical Sciences

Dr. Rademacher received her Med.Vet. from the Justus-Liebig-University (Germany) in 2000 and her Dr.med.vet. from the University

of Berne (Switzerland) in 2003. After completion of a small animal internship in a private referral center in Switzerland, she completed

a diagnostic imaging residency in 2006 at the Vetsuisse Faculty (Switzerland). Dr. Rademacher is a Diplomate of both the European

College of Veterinary Diagnostic Imaging and the American College of Veterinary Radiology. She joined the faculty of the LSU SVM

in 2007. Dr. Rademacher’s research focus is ultrasound in small and large animals, contrast enhanced ultrasound of the pancreas in

dogs and cats, elastographic ultrasound application and lung ultrasound in dogs.

Laura Riggs, DVM, PhD, DACVS, Associate Professor of Equine Surgery, Veterinary Clinical Sciences

Dr. Riggs is originally from Memphis, Tenn., and received her DVM from the University of Tennessee College of Veterinary Medicine

in 2001. She completed a large animal internship followed by a large animal surgery residency at the University of Georgia. In 2007

she received her PhD in veterinary physiology from the University of Georgia with research studying biomarkers in equine laminitis.

Dr. Riggs is a Diplomate of the American College of Veterinary Surgeons. Her research focuses on lameness, laminitis and fracture

repair biomechanics.

Clare Scully, MA, DVM, MS, Assistant Professor of Food Animal Health Maintenance, Veterinary Clinical Sciences

Dr. Scully received her DVM from the University of Tennessee in 2011 and received her MS from Oregon State University in 2015.

She is board certified in the American College of Theriogenology. Her clinical interests include advanced reproduction techniques

in ruminants, pain management in food animals, as well as food animal surgery. In 2013 Dr. Scully won the Western Veterinary

Conference Food Animal Incentive Award and was awarded the Society of Theriogenology Emerging Leader Scholarship in 2014. Dr.

Scully joined the faculty in 2015.

Jennifer Sones, DVM (LSU SVM 2008), PhD, DACT, Assistant Professor of Theriogenology, Veterinary Clinical Sciences

Dr. Sones received her BS from LSU in 2004 and her DVM from the LSU School of Veterinary Medicine in 2008. She received

her PhD from Cornell University in 2014 in molecular and integrative physiology. . She completed her theriogenology residency at

Cornell and is board certified in the American College of Theriogenology. Dr. Sones joined the faculty in 2015. Her research interests

include comparative pregnancy physiology, preeclampsia and fetal growth restriction and equine placentitis.

Changaram S. Venugopal, BVSc, MSc, MS, PhD, Professor Emeritus, Veterinary Clinical Sciences

Dr. Venugopal received his BVSc from Kerala Veterinary College and Research Institute at Kerala University (India). After

practicing veterinary medicine at the Kamadhenu Dairy Farm for five years, he pursued advanced studies and received his MSc

11

FACULTY

Veterinary Sports Medicine and Rehabilitaton

Advanced equine lameness diagnosis

Advanced imaging (MRI, CT, ultrasonography,

radiographs, nuclear scintigraphy, dynamic

ultrasound)

Performance evaluation

Podiatry and advanced therapeutic farrier service

Integrative medicine service (shock wave,

acupuncture, therapeutic and service massage)

Full-service veterinary hospital

Veterinary Teaching Hospital

24-hour care

Skip Bertman Drive at River Road Baton Rouge, LA 70803

225-578-9500lsu.edu/vetmed

in neuropharmacology from Calicut University (India). He later received his MS degree in cardiovascular pharmacology and a PhD

in pulmonary pharmacology from the Massachusetts College of Pharmacy and Allied Health Sciences in a cooperative program

with Harvard University in Boston, Mass. Then he worked as a post-doctoral fellow at Harvard Medical School and, in 1981, joined

the faculty at the LSU SVM. He received the New Investigator Award grant from the National Institutes of Health in 1983 and the

Beecham Award for Research Excellence in 1985. He received the Faculty Distinguished Scholar Award in 2003 from the LSU SVM

and the Distinguished Alumni Award from his alma mater in 2005. His research interests include recurrent airway obstruction in

horses, mediators of airway hyperreactivity, pathophysiology of insulin resistance in equine laminitis, pharmacology of vasculature,

and oxidative stress in equine respiratory diseases. He is the recipient of research grants as principal investigator from the National

Institutes of Health, the USDA and the Grayson Jockey Research Foundation, as well as grants from the National Institute of

Environmental Health Science and the Louisiana Board of Regents as co-principal investigator. In the area of teaching, Dr. Venugopal

has been on the honor roll in merit teaching from 1994-99, and he received an LSU School of Veterinary Medicine Teaching Award in

2008.

Matt Welborn, DVM, MPH, ACVPM, Professor of Food Animal Health Management, Veterinary Clinical Sciences

Dr. Welborn received his DVM from the LSU School of Veterinary Medicine in 1987 and his MPH from the University of Tennessee in

2005. He is a Diplomate of the American College of Veterinary Preventive Medicine, and his specialty is in farm animal production

medicine. His research and clinical interests are in veterinary public health, agroterrorism, emergency preparedness and toxic plants.

Dr. Welborn joined the faculty in 2012.

Michelle Woodward, DVM, MS (LSU SVM 2014), DACVD, Assistant Professor of Veterinary Dermatology, Veterinary Clinical Sciences

Dr. Woodward joined the faculty in March 2016. She received her BS from the Rose-Hulman Institute of Technology in 2005 and her

DVM from the University of Tennessee in 2009. She received her MS in 2014 from the LSU School of Veterinary Medicine, where

she also completed her residency in veterinary dermatology. Dr. Woodward is a Diplomate of the American College of Veterinary

Dermatology. Her research interests include equine hypersensitivity/allergy and bacterial resistance in the clinical setting.

12

GRADUATE PROGRAM

David Beehan, MVB, PhD, DACT

David Paul Beehan, MVB, MS, DipACT (Athgarvan, Newbridge, Ireland), received his PhD in December 2016 from the Department

of Veterinary Clinical Sciences (VCS). Dr. Beehan’s dissertation was entitled, “The Investigation of Biofilm Formation by Equine

Reproductive Tract Escherichia Coli,” and his major advisor was Sara Lyle, DVM, PhD, DACT, adjunct assistant professor in VCS.

Since completing his dissertation, Dr. Beehan has returned to Ireland, where he has taken a position as a veterinarian with the Irish

Department of Agriculture. He currently works at the central office in Dublin for a section responsible for infectious disease.

Wei Duan, MS, PhD

Wei Duan, PhD, received his PhD degree from the LSU School of Veterinary Medicine in August 2017. He was part of the Laboratory

for Equine and Comparative Orthopedic Research and worked with Mandi Lopez, DVM, PhD, DACVS, director of LECOR. Dr. Duan’s

experience includes four years of biomaterials and human stem cell research and four years of canine, equine, and feline adipose

derived stem cells research and bioreactor designing. The majority of his research work is within the field of biomaterials and tissue

regeneration, specifically equine bone and feline diabetes mellitus. Dr. Duan is currently working on the regenerative medicine in

feline diabetes.

Nicole Marie Hanson, BA, BS, PhD, Certificate in Prosthetics

Nicole Marie Hanson, BA, BS, Certificate in Prosthetics (Grafton, Wis.), received her PhD in December 2016 from VCS. Dr. Hanson’s

dissertation was entitled, “Evaluation and Biomechanical Analysis of Equine Prosthetics,” and her major advisor was Laura Riggs,

DVM, PhD, DACVS, associate professor of equine surgery VCS. Upon graduation, Dr. Hanson plans to continue operating her

business, Bayou Time Babysitting and Nannies, and hopes to start a charitable foundation and educate the community about

veterinary prosthetics.

Heather Richbourg, PhD

Heather A. Richbourg, PhD, received her BS from Young

Harris College in 2013 and her PhD from the LSU School

of Veterinary Medicine in 2017. Her mentor was Margaret

McNulty, PhD, [then] assistant professor in Comparative

Biomedical Sciences. Dr. Richbourg’s dissertation is

entitled “Microscopic Evaluations of Bone in Equine and

Mucoid Models.”

Michelle Woodward, BS, DVM, DACVD

Michelle Woodward, BS, DVM (Bloomington, Ill.) received

her MS in May 2014 from VCS. Her thesis was entitled,

“Characterization of IgE-Mediated Cutaneous Immediate

and Late-phase Reactions in Non-allergic Horses,” and

her major advisor was Frank Andrews, DVM, DACVIM,

director of the equine health studies program and

professor of veterinary medicine. Dr. Woodward is

currently an assistant professor of veterinary dermatlogy

at the LSU SVM.

Dr. Mandi Lopez, professor in Veterinary Clinical Sciences, with Dr. Wei

Duan on the day he received his PhD from LSU.

13

PUBLICATIONS, ABSTRACTS AND PROCEEDINGS

PUBLICATIONS

TEXTBOOK CHAPTERS

Leise, B. S. (2016). Inflammatory Signaling. In Belknap, J. K., Geor, R. J. (Ed.), Equine Laminitis.

Pinto, C. R. (2015). Artificial Insemination. Cote/Clinical Veterinary Advisor: Dogs and Cats, (ed. 3).

Pinto, C. R. (2015). Vaginal Palpation in the Bitch. Cote/Clinical Veterinary Advisor: Dogs and Cats, (ed. 3).

Pinto, C. R. (2015). Vaginoscopy. Cote/Clinical Veterinary Advisor: Dogs and Cats, (ed.3).

Woodward, M., Ramos, S. (2016). Calcification Disorders of Skin. In Tater, K. (Ed.), Veterinary Information Network Associate. Davis,

California: Veterinary Information Network. Published Electronically www.vin.com/Members/Associate/Associate.plx?from=GetDz

Info&DiseaseId=392 Woodward (2016). Cutaneous Mucinosis. In Tater, K. (Ed.), Veterinary Information Network Associate. Davis,

California: Veterinary Information Network. Published Electronically. www.vin.com/Members/Associate/Associate.plx?from=GetDzInfo

&DiseaseId=377

Proceedings

Andrews, F. M. (2015). Equine Cushing’s Disease (PPID): Not Just Your Father’s Wooly Mamoth (pp. 4-8). Mississippi Veterinary

Medical Association. Alabama.

Andrews, F. M. (2015). Equine Gastric Ulcer Syndrome: A pain in the Gut! (pp. 1-3). Mississippi Veterinary Medical Association.

Alabama.

Andrews, F. M. (2015). Gastroscopy – Technique & Interpretation (pp. 48-53). Veterinary Professional Development. Nevada.

Andrews, F. M. (2015). In Engeli, E. (Ed.), Usefulness of Haematology/Biochemistry ‘Screening’ (pp. 60-67). Veterinary Professional

Development. Nevada.

Andrews, F. M. (2015). In Engeli, E. (Ed.), Using Pulse & Lactate for Training/Rehabilitation Management (pp. 79-86). Veterinary

Professional Development. Nevada.

Andrews, F. M., Shannon, D., Camacho-Luna, P., Keowen, M. L., Garza, Jr., F., Roy, A. F., Keene, R., Grubbs, S., Doyle, T., Lyle, S. K.

(2016). IgM and IgG Response of Horses and Pony Foals after Vaccination for West Nile Virus and Eastern Equine Encephalitis (vol.

62, pp. 233-234). Orlando, Florida: Proceeding 62nd Annual Convention of the American Association of Equine Practitioners. www.

aaep.org

Armstrong, C. L., Wolfe, D. F., Koziol, J., Edmondson, M. A. (2015). Lameness in Breeding Bulls. (3rd ed., vol. 7, pp. 249-253). Clinical

Theriogenology. Therio.org.

Armstrong, C. L. (2016). Bull Breeding Soundness Exam-Morphologic Slide Preparation and Assessment. Alabama Veterinary Medical

Association. alvma.org

Camacho-Luna, P., Andrews, F. M., Gaschen, L., Markle, M., Keowen, M. L., Garza, Jr., F., Kearney, M. T., Storey, E. S. (2016). Effects

of 1% Ophthalmic Atropine Sulfate Solution on Gastrointestinal Motility and Transit Time in Healthy Horses (vol. 62, pp. 495-496).

Orlando, Florida: Proceeding 62nd Annual Convention of the American Association of Equine Practitioners. www.aaep.org

Carter, R. T. (2016). Glaucoma medications: What Drug to Choose? North American Veterinary Conference.

Carter, R. T. (2016). Ocular Complications of Endocrine Diseases in Dogs and Cats. North American Veterinary Conference.

14


Carter, R. T. (2016). Underlying Disorders that Complicate Ocular Health. Louisiana State University.

Carter, R. T. (2016). Your Ophthalmoscope: How to Get the Most From It. North American Veterinary Conference.

Cremer, J. (2016). Adrenal Glands - Cushings Disease.

Cremer, J. (2016). Diabetes mellitus and Insulinoma.

Cremer, J. (2016). Hyper- and Hypothyroidism.

Koh, R. (2016). Traditional Chinese Veterinary Medicine for Sleeping Disorders. Reddick, Florida: International Traditional Chinese

Veterinary Medicine Conference.

Leise, B. (2016). Regional Limb Perfusion in the Horse: Update on Use. North American Veterinary Conference.

Leise, B. (2016). Wounds Associated with Synovial Structures: Diagnosis and Management. North American Veterinary Conference.

Leise, B. (2016). Wounds of the Chest and Abdomen. North American Veterinary Conference.

McConnico, R. S. (2015). Equine Medicine “911”. Proceedings of the 87th Western Veterinary Conference - Nevada: WVC Learning

Library. http://library.wvc.org/vrtags/media/666

McConnico, R. S. (2015). Horse Hot Zone: Care and Management of Equine Infectious Disease Cases. Proceedings of the 87th

Western Veterinary Conference – Nevada: WVC Learning Library. http://library.wvc.org/vrtags/media/666

McConnico, R. S. (2015). Preventing Pestilence. Proceedings of the 87th Western Veterinary Conference - Nevada: WVC Learning

Library. http://library.wvc.org/vrtags/media/666

McConnico, R. S. (2015). The Veterinarian’s Role in Cases of Equine Cruelty. Proceedings of the 87th Western Veterinary Conference

- Nevada: WVC Learning Library. http://library.wvc.org/vrtags/media/666.

McConnico, R. S. (2016). Biosecurity Considerations for Equine Emergency Sheltering. College Station, Texas: Proceedings of the

2016 NASAAEP Summit.

Mitchell, C. F. (2015). A Diagnostic Approach to Evaluating Lower Limb Lameness. Mississippi Veterinary Medical Association.

Mitchell, C. F. (2015). Distal Limb Lameness. Mississippi Veterinary Medical Association.

Mitchell, C. F. (2015). New Treatments for Navicular Disease. Louisiana Veterinary Medical Association.

Mitchell, C. F. (2015). Update on Navicular Disease. Louisiana Veterinary Medical Association.

Paccamonti, D. L. (2016). Ovulatory Failure: Contributing Factors and Possible Management Strategies (pp. 234-236). Leipziger Blaue

Hefte, 9th International Congress on Equine Reproductive Medicine.

Pinto, C. R., Coffman, E. A. (2015). Efeito Antiluteogenico da Prostaglandina F2α (1st ed., vol. 39, pp. 15–16). Revista Brasileira de

Reproducao Animal.

Pinto, C. R. (2015). O Processo Inflamátorio na Formacao do Corpo Luteo da Égua (1st ed., vol. 39, pp. 121–122). Revista Brasileira de

Reproducao Animal.

Pucheu-Haston, C. M. (2015). Allergic Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015.

Published Electronically.

15


Pucheu-Haston, C. M. (2015). Fungal Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015.


Pucheu-Haston, C. M. (2015). Parasitic Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015.


Pucheu-Haston, C. M. (2015). Techniques in Equine Dermatology. Louisiana Veterinary Medical Association Equine Seminar 2015.


Pucheu-Haston, C. M. (2015). Therapeutics for Skin Disease in the Horse. Louisiana Veterinary Medical Association Equine Seminar

2015. Published Electronically.

Pucheu-Haston, C. M. (2016). Antibiotic Resistant Skin Infections: What Antibiotics to Use Now? Orlando, Florida: North American

Veterinary Community (NAVC).

Pucheu-Haston, C. M. (2016). Better Skin Biopsies: How to Get the Most from Your Samples. Orlando, Florida: North American

Veterinary Community (NAVC).

Pucheu-Haston, C. M. (2016). Optimizing Your Microscope for Dermatologic Samples. Louisiana State University Dermatology

Continuing Education Seminar Series 2016.

Pucheu-Haston, C. M. (2016). Optimizing your Microscope for Dermatologic Samples. Orlando, Florida: North American Veterinary

Community (NAVC).

Pucheu-Haston, C. M. (2016). Top Ten Reasons Otitis Treatments Fail. Louisiana State University Dermatology Continuing Education

Seminar Series 2016.

Pucheu-Haston, C. M. (2016). When It’s Not Just an Abscess. Louisiana State University Dermatology Continuing Education Seminar

Series 2016.

Rademacher, N. (2016). Basic Physics, Knobology and Ultrasound Artifacts. Rademacher, N. (2016). FLASH Ultrasound of the

Abdomen. Published Electronically

Rademacher, N. (2016). Ultrasonography of the Abdomen - Abnormal Appearance.

Rademacher, N. (2016). Ultrasonography of the Abdomen - Normal Appearance.

Rademacher, N. (2016). Ultrasound Guided Tissue Sampling: Tips, Tricks and Indications.

Riggs, L. M. (2015). Acute Wounds: When to be Concerned. North American Veterinary Conference. Published Electronically.

Riggs, L. M. (2015). Field Anesthesia: The Cliff’s Notes. North American Veterinary Conference. Published Electronically.

Riggs, L. M. (2015). Field Treatments for Colic: More Options Than You Think. North American Veterinary Conference. Published

Electronically.

Riggs, L. M. (2015). Never Too Young to Colic. North American Veterinary Conference. Published Electronically.

Riggs, L. M. (2015). Sedation and Local Anesthesia for Standing Surgery: Tips for Success. North American Veterinary Conference.


Riggs, L. M. (2015). Standing Surgical Procedures: No anesthesia, No problem. North American Veterinary Conference. Published

Electronically.

16


Riggs, L. M. (2016). Acute Wounds: When to be Concerned. Kansas City, Missouri: CVC- Veterinary Continuing Education. Published

Electronically.

Riggs, L. M. (2016). Chronic Wounds. Kansas City, Missouri: CVC- Veterinary Continuing Education. Published Electronically.

Riggs, L. M. (2016). Colic in Foals. Kansas City, Missouri: CVC- Veterinary Continuing Education. Published Electronically.

Riggs, L. M. (2016). Dealing with Thoracic and Abdominal Wounds. Kansas City, Missouri: CVC- Veterinary Continuing Education.


Riggs, L. M. (2016). Exercising Upper Airway Endoscopy: A Game Changer. Kansas City, Missouri: CVC- Veterinary Continuing

Education. Published Electronically.

Riggs, L. M. (2016). Sedation and Local Anesthesia for Standing Surgery: Tips for Success. Kansas City, Missouri: CVC- Veterinary

Continuing Education. Published Electronically.

Riggs, L. M. (2016). Standing Surgery Procedures: No General Anesthesia? No Problem! Kansas City, Missouri: CVC- Veterinary

Continuing Education. Published Electronically.

Riggs, L. M. (2016). Updates on Treating Upper Airway Disease. Kansas City, Missouri: CVC- Veterinary Continuing Education.


Woodward, M. (2016). Calcinosis Cutis/Osteoma Cutis. Louisiana State University Dermatology Continuing Education Seminar Series

(pp. 4). Baton Rouge, Louisiana, Louisiana State University SVM.

Woodward, M. (2016). Optimizing Your Skin Biopsy. Louisiana State University Dermatology Continuing Education Seminar Series (pp.

3). Baton Rouge, Louisiana, Louisiana State University SVM.

Woodward, M. (2016). Topical Therapy with a Focus on Topical Therapy for Bacterial Skin Disease. Louisiana State University

Dermatology Continuing Education Seminar Series (pp. 5). Baton Rouge, Louisiana, Louisiana State University SVM.

Lay Publications

Andrews, F. M. (2016). In Milazzo, M. (Ed.), New Foal? What Should be Done? (vol. Stallion Issue, pp. 19). Gonzales, Louisiana:

Louisiana Equine Report. Published Electronically theequinereport.com

Andrews, F. M., Camacho-Luna, P., Gaymon, G., Loftin, P., Keowen, M., Garza, Jr., F., Kearney, M. T. (2016). In Milazzo, M. (Ed.), The

Supplement, SmartGut Ultra, Maintains Stomach Health After Ulcer Treatment! (1st ed., vol. 5, pp. 69). Gonzales, Louisiana: Louisiana

Equine Report. Published Electronically theequinereport.com

Armstrong, C. L. (2016). The Bull Breeding Soundness Exam-Why it is Critical to the Overall Success of the Operation. San Antonio,

Texas: Gulf Coast Cattleman. Published Electronically http://www.gulfcoastcattleman.com/

McCauley, C. T. (2016). Clinical Evaluation of Lameness in Foals (vol. June/July 2016). The Equine Report.

McConnico, R. S. (2015). Louisiana State Animal Response Team Leads the Way in Animal Response. Emergency Response

Magazine. www.emergencymgmt.com/disaster/Louisiana-State-Animal-Response-Team.html

McConnico, R. S. (2016). Equine Community Helps Horses Affected By Louisiana Flooding. Chronicle of the Horse. chronofhorse.

com/article/community-helpshorses-affected-louisiana-flooding

McConnico, R. S., Addison, J. (2016). Flooding Challenges Humans, Horses in Louisiana. TheHorse.com. www.thehorse.com/

articles/38013/floodingchallenges-humans-horses-in-louisiana

17


McConnico, R. S. (2016). Horses Evacuated From Louisiana Flood Heading Home. www.thehorse.com/articles/38091/

horses-evacuated-from-louisiana-floodheading-home

Newtown, B., Andrews, F. M. (2016). In Milazzo, M. (Ed.), Q and A with Dr. Frank Andrews of the LSU Equine Health Studies Program

(6th ed., vol. 4, pp. 1-23). Gonzales, Louisiana: Louisiana Equine Report. Published Electronically theequinereport.com

Oberhaus, E. L., Sones, J. (2016). Seasonality of Reproduction in Horses. The Equine Report. theequinereport.com/2016/09/

seasonality-of-reproduction-in-horses/

Riggs, L. M. (2015). Scope on the Geaux: Evaluation of the Horse’s Airway! (April/May 2015 ed., pp. 35). Louisiana Equine Report:

Louisiana Equine Report.

Scully, C. (2015). Equine Theriogenology Services at OSU. The Oregon Horse (vol. Breeding Issue, pp. 25). Oregon Thoroughbred

Owners and Breeders Association. Portland, Oregon.

Sones, J. (2016). Breeding Success After a Racing Career (2nd ed., vol. 5). Louisiana Equine Report.

Continuing Education Presentations

International

Andrews, F. M., (Author & Presenter). Equine Poor Performance & Rehabilitation for Practitioners, “Gastroscopy – Technique &

Interpretation.” Veterinary Professional Development (VetPD). Las Vegas, NV. (April 2015).

Andrews, F. M., (Author & Presenter). Equine Poor Performance & Rehabilitation for Practitioners, “Gastroscopy, Wet lab,” Veterinary

Professional Development (VetPD). Las Vegas, NV. (April 14, 2015).

Andrews, F. M., (Author & Presenter). Equine Poor Performance & Rehabilitation for Practitioners, “Usefulness of Haematology/

Biochemistry ‘Screening’.” Veterinary Professional Development (VetPD). Las Vegas, NV. (April 2015).

Andrews, F. M., (Author & Presenter). Equine Poor Performance & Rehabilitation for Practitioners, “Using Pulse & Lactate for Training /

Rehabilitation Management,” Veterinary Professional Development (VetPD). Las Vegas, NV. (April 2015).

Koh, R., China Acupuncture Course, Acupuncture: Evidence-Based and Clinical Applications. Chi Institute of Chinese Medicine.

Guangzhou, China. (May 2015).

Koh, R. (Presenter), Grand Rounds Seminar, “Improving Neurologic and Orthopedic Outcomes with Rehabilitation,” National Taiwan

University College of Veterinary Medicine, Taipei City, Taiwan. (September 6, 2016).

Koh, R. (Presenter), Grand Rounds Seminar, “Improving Neurologic and Orthopedic Outcomes with Rehabilitation,” National Chung

Hsing University College of Veterinary Medicine, Taichung City, Taiwan. (September 2, 2016).

Koh, R. (Presenter), Hongkong Veterinary Seminar, “Rehabilitation for Intervertebral Disc Disease,” Hongkong Veterinary Medical

Association, Hongkong, China. (May 24, 2016).

Koh, R. (Presenter), Hongkong Veterinary Seminar, “Traditional Chinese Veterinary Medicine for Intervertebral Disc Disease,”

Hongkong Veterinary Medical Association, Hongkong, China. (May 24, 2016).

Koh, R. (Presenter), Moscow Veterinary Congress, “Intro to Traditional Chinese Veterinary Medicine,” Moscow Veterinary Medical

Association, Moscow, Russia. (April 24, 2016).

18


Koh, R. (Presenter), Moscow Veterinary Congress, “Most Researched Acupoints and their Clinical Applications,” Moscow Veterinary

Medical Association, Moscow, Russia. (April 24, 2016).

Koh, R. (Presenter), Moscow Veterinary Congress, “The Science behind Veterinary Acupuncture,” Moscow Veterinary Medical


Koh, R. (Presenter), Moscow Veterinary Congress, “Understanding Acupuncture and How It Could Benefit Your Patients,” Moscow

Veterinary Medical Association, Moscow, Russia. (April 24, 2016).

Mirza, M. H., LSART Boot Camp 2015, Large Animal Rescue. LDAF,LSART,IFAW, NASAAEP,USDA and People of Humane Society.

(August 2015).

Paccamonti, D. L., Corso de Diplomado en Reproducion en Equinos, (Diagnostic Techniques for Mare Infertility: How Times Have

Changed) AMMVEE. Guadalajara, Mexico. (March 2015).

Paccamonti, D. L., Corso de Diplomado en Reproducion en Equinos, (Uterine Biopsy: Time to Re-evaluate?) AMMVEE, Guadalajara,

Mexico. (March 2015).

Paccamonti, D. L., Corso de Diplomado en Reproducion en Equinos, (Uterine Therapy for the Infertile Mare). AMMVEE, Guadalajara,


Paccamonti, D. L., 9th International Congress on Equine Reproductive Medicine, “Ovulatory Failure: Contributing Factors and

Possible Management Strategies.” (January 2016).

National

Andrews, F. M. (Author & Presenter), BIVI CE Meeting at the American Rodeo, “Viral Respiratory Disease in Horses,” Boehringer

Ingelheim Vetmedica, Arlington, Texas. (February 28, 2016).

Armstrong, C., Alabama Veterinary Medical Association 25th Annual Food Animal Conference, “Bull Breeding Soundness Exam:

Morphologic Slide Preparation and Assessment,” ALVMA, Columbiana, Alabama. (February 21, 2016).

Carter, R. T., North American Veterinary Conference, “Glaucoma Medications: What Drugs to Choose?” (January 18, 2016).

Carter, R. T., North American Veterinary Conference, “Management of Ocular Emergencies: Case Discussion (Masterclass).” (January

17, 2016).

Carter, R. T., North American Veterinary Conference, “Your Ophthalmoscope: How to Get the Most From It.” (January 18, 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Equine Wounds: Case Discussions,” Orlando, Florida.

(January 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Regional Limb Perfusion in the Horse: Update on Use,”

Orlando, Florida. (January 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Wounds Associated with Synovial Structures: Diagnosis

and Management,” Orlando, Florida. (January 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Wounds of the Chest and Abdomen,” Orlando, Florida.

(January 2016).

Leise, B. (Author & Presenter), Miller, N., Moorman, V., Bass, L., Pittman, S., Rucker, A., Redden, R., AAEP 62nd Annual Convention,

19


“Assessment of Digital Venograms in Non-Laminitic Horses,” American Association of Equine Practitioners, Orlando, Florida.

(December 2016).

McConnico, R. S., Katrina Commemorative Animal Responder Boot Camp. Large Animal Technical Emergency Rescue. LSART-LVMA-

ASPCA-IFAW-NASAAEP-AHA-RR. Baton Rouge, LA. (August 2015).

McConnico, R. S., Equine Medicine 911. Western Veterinary Conference, Las Vegas, NV. (February 16, 2015).

McConnico, R. S., Horse Hot Zone: Care and Management of Equine Infectious Disease Cases. Western Veterinary Conference. Las

Vegas, NV. (February 2015).

McConnico, R. S., Preventing Pestilence. Western Veterinary Conference. Las Vegas, NV. (February 16, 2015).

McConnico, R. S., The Veterinarian’s Role in Cases of Equine Cruelty. Western Veterinary Conference. Las Vegas, NV. (February 16,

2015).

McConnico, R. S. (Author & Presenter), Animal Welfare Symposium for Veterinary Students, “The Impact of Equine Welfare Issues on

the Animal,” Humane Society Veterinary Medical Association, LSU-Vet Med. (November 12, 2016).

Mirza, M. H., Large Animal Rescue Techniques. LDAF. (September 2015).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Antibiotic Resistant Skin Infections: What

Antibiotics to Use Now?” North American Veterinary Community, Orlando, Florida. (January 17, 2016).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Better Skin Biopsies: How to Get the Most From

Your Samples,” North American Veterinary Community, Orlando, Florida. (January 17, 2016).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Medical Management of Pruritus: The Good, the

Bad and the Ugly,” North American Veterinary Community, Orlando, Florida. (January 16, 2016).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Optimizing Your Microscope for Dermatologic

Samples,” North American Veterinary Community, Orlando, Florida. (January 17, 2016).

Pucheu-Haston, C. M., Whole Horse Wellness Seminar, “Techniques in Equine Dermatology,” Kinetic Vet, Nashville, Tennessee. (July

23, 2016).

Rademacher, N. (Presenter), LSU Abdominal Ultrasound Course, “Tissue Sampling - FNA and Biopsy Basics,” Universal Ultrasound,

Baton Rouge, Louisiana. (September 25, 2016).

Rademacher, N. (Author & Presenter), NAVC-North American VeterinaryCommunity, “FLASH Ultrasound of the Abdomen,” Orlando,

Florida. (January 19, 2016).

Riggs, L. M., North American Veterinary Conference, “Acute Wounds: When to be Concerned,” NAVC, Orlando, Florida. (January 17,

2016).

Riggs, L. M., North American Veterinary Conference, “Field Anesthesia: The Cliff’s Notes,” NAVC, Orlando, Florida. (January 17, 2016).

Riggs, L. M., North American Veterinary Conference, “Field Treatments for Colic: More Options Than You Think,” NAVC, Orlando,


Riggs, L. M., North American Veterinary Conference, “Never Too Young to Colic,” NAVC, Orlando, Florida. (January 17, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Acute Wounds: When to Worry,” CVC, Kansas City, Missouri. (August 28, 2016).

20


Riggs, L. M., Veterinary Continuing Education (CVC), “Chronic Wounds,” CVC, Kansas City, Missouri. (August 28, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Colic in Foals,” CVC, Kansas City, Missouri. (August 28, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Dealing with Thoracic and Abdominal Wounds,” CVC, Kansas City, Missouri.

(August 29, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Exercising Upper Airway Endoscopy,” CVC, Kansas City, Missouri. (August 29,

2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Sedation and Local Anesthesia for Standing Surgery,” CVC, Kansas City,

Missouri. (August 29, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Standing Surgical Procedures,” CVC, Kansas City, Missouri. (August 29, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Updates on Treating Upper Airway Disease,” CVC, Kansas City, Missouri.

(August 29, 2016).

Welborn, M. G. (Presenter), Common Toxic Plants Affecting Small and Large Animals. Southwest Veterinary Symposium. Ft. Worth, TX.

(September 26, 2015).

Welborn, M. G. (Presenter), Update on Zoonotic Diseases. Southwest Veterinary Symposium. Ft. Worth, TX. (September 26, 2015).

State and Local

Andrews, F. M. (Author & Presenter), Equine Cushing Disease: Not your Father’s Wooly Mammoth! Mississippi VMA Summer

Conference. Columbus, Ohio. (July 2015).

Andrews, F. M. (Author & Presenter), Gastric Ulcers: A Pain in the Gut! Mississippi VMA Summer Conference. Perdido Beach, AL. (July

2015).

Andrews, F. M. (Author & Presenter), A Pain in the Gut: Equine Gastric Ulcers. 84th Annual Conference for Veterinarians and

Veterinary Technicians. Louisiana State University, Baton Rouge, Louisiana. (April 2015).

Andrews, F. M. (Author & Presenter), Case Studies in Equine Medicine. Midwest Veterinary Conference. Columbus, Ohio. (February

2015).

Andrews, F. M. (Author & Presenter), Colic: Making Decisions, Referrals, and Prognosis. Midwest Veterinary Conference. Columbus,

Ohio. (February 2015).

Andrews, F. M. (Author & Presenter), Colonic Ulcers: A Pain in the Hindgut! Midwest Veterinary Conference. Columbus, Ohio.

(February 2015).

Andrews, F. M. (Author & Presenter), Equine Cushing Disease: No your Father’s Wooly Mammoth! Midwest Veterinary Conference.

Columbus, Ohio. (February 2015).

Andrews, F. M. (Author & Presenter), Gastric Ulcers: A pain in the Gut! Midwest Veterinary Conference. Columbus, Ohio. (February

2015).

Andrews, F. M. (Author & Presenter), Gastric Ulcers: Relieving the Pain! Midwest Veterinary Conference. Columbus, Ohio. (February

2015).

21


Andrews, F. M. (Author & Presenter), An Update on Equine Gastric Ulcer Syndrome. LVMA Annual Winter Meeting. Lafayette, LA.

(January 2015).

Andrews, F. M. (Author & Presenter), Colic: A Model for Surgery and Survival. LVMA Annual Winter Meeting. Lafayette, LA. (January

2015).

Andrews, F. M. (Author & Presenter), Equine Gastric Ulcer Syndrome: What About Supplements? LVMA Annual Winter Meeting.

Lafayette, LA. (January 2015).

Andrews, F. M., 85th LSU SVM Annual Conference for Veterinarians and Veterinary Technicians, “Am I Giving My Horse a Stomach

Ulcer?” Louisiana State University SVM, Baton Rouge, Louisiana. (April 16, 2016).

Carter, R. T., LSU Alumni Homecoming CE, “Underlying Disorders That Complicate Ocular Health,” Louisiana State University SVM,

Baton Rouge, Louisiana. (October 15, 2016).

Chapman, A. M., The Fat Horse: Update on Equine Metabolic Syndrome. Partnering for Large Animal Health Educational Series.

Louisiana State University. Baton Rouge, LA. (August 2015).

Chapman, A. M. (Author & Presenter), Equine Medical Emergencies. Annual Conference for Veterinarians and Technicians. Louisiana

State University. Baton Rouge, Louisiana. (April 2015).

Chapman, A. M. (Author & Presenter), Annual Meeting, “Understanding Equine Fluid Therapy,” Louisiana Veterinary Medicine

Association, Shreveport, Louisiana. (January 31, 2016).

Cremer, J., BRAVMA, “Hemoabdomen,” Baton Rouge, Louisiana. (April 12, 2016).

De Caro Carella, C., Continuing Education for Technicians, “Moving Into the Future with the Digital Anesthetic Record,” Louisiana

State University SVM, Baton Rouge, Louisiana. (December 5, 2016).

Eades, S. C., Equine Laminitis. Partnering for Large Animal Health Education Series. Equine Health Studies Program, Louisiana State

University. Baton Rouge, Louisiana. (August 2015).

Granger, L. A., U-Learn Ultrasound, “Abnormal: Liver and Spleen,” Universal Ultrasound and LSU, Louisiana State University SVM,

Baton Rouge, Louisiana. (April 10, 2016).

Granger, L. A., U-Learn Ultrasound, “Abnormal: Lymph Nodes and Mesentery,” Universal Ultrasound and LSU, Louisiana State

University SVM, Baton Rouge, Louisiana. (April 10, 2016).

Granger, L. A., U-Learn Ultrasound, “Abnormal: Urogenital Tract,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Basic Physics of Ultrasound,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Normal Organ Appearance,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Patient Preparation and Tissue Sampling,” Universal Ultrasound and LSU, Louisiana State


Granger, L. A., U-Learn Ultrasound, “Ultrasound Equipment,” Universal Ultrasound and LSU, Louisiana State University SVM, Baton

Rouge, Louisiana. (April 9, 2016).

22


Koh, R., Chinese Herbal Medicine and Food Therapy in Veterinary Practice. Oklahoma State University Integrative Medicine Club

Meeting. Oklahoma State University Integrative Medicine Club, Oklahoma. (October 2015).

Koh, R., Integrative Medicine: Acupuncture and Its Integration into Conventional Medicine. Oklahoma State University Grand Seminar.

Oklahoma State University School of Veterinary Medicine. Oklahoma. (October 2015).

Koh, R., Intro to Integrative Medicine. Louisiana State University Integrative Medicine Club Meeting. Louisiana State University

Integrative Medicine Club. Baton Rouge, Louisiana. (September 2015).

Koh, R. (Presenter), LVMA Winter Meeting, “Acupuncture - Science-Based Medicine,” LVMA, Shreveport, Louisiana. (January 29, 2016).

Koh, R. (Presenter), LVMA Winter Meeting, “Integrative Medical Approach to Common Clinical Problems in Small Animals,” LVMA,

Shreveport, Louisiana. (January 29, 2016).

Koh, R. (Presenter), LVMA Winter Meeting, “Rehabilitation in Hindlimb,” LVMA, Shreveport, Louisiana. (January 29, 2016).

Leise, B. S. (Author & Presenter), Louisiana State University SVM Annual Conference– Technician’s Forum, “Equine Wound

Management,” Baton Rouge, Louisiana. (April 2016).

Lopez, M. J., 39th Annual Louisiana Veterinary Medical Association Equine Seminar, “Platelet Rich Plasma and Stem Cells,”

Shreveport, Louisiana. (September 25, 2016).

Lopez, M. J., Annual Meeting of Louisiana Professional Association of Therapeutic Horsemanship, “Platelet Rich Plasma to Alleviate

Signs of Osteoarthritis in Horses,” Annual Meeting of Lo, Baton Rouge, Louisiana. (January 31, 2016).

Magee, A., BRAVMA monthly meeting, “Interpreting ECGs,” BRAVMA, Baton Rouge, Louisiana. (January 2016).

Magee, A., SVM Annual Conference, “ECG Interpretation for Technicians,” Louisiana State University SVM, Baton Rouge, Louisiana.

(April 2016).

McCauley, C. T., Suspensory Ligament Disease. Louisiana Veterinary Medical Association Winter Meeting. Louisiana Veterinary

Medical Association. Lafayette, LA. (January 2015).

McCauley, C. T., Suspensory Ligament Disease. Partnering for Large Animal Health Education Series. Louisiana State University SVM,

Baton Rouge, LA. (August 2015).

McCauley, C. T. (Presenter), 2016 Louisiana Society or Radiological Technology Annual Meeting, “Application of Diagnostic Imaging

Technology to Veterinary Medicine,” Louisiana Society of Radiological Technology, Baton Rouge, Louisiana. (July 9, 2016).

Mitchell, C. F., A Diagnostic Approach to Lower Limb Lameness. Mississippi Veterinary Medical Association. Mississippi Veterinary

Medical Association, Perdido Bay, Alabama. (July 2015).

Mitchell, C. F., An Update on Navicular Disease. Louisiana Veterinary Medical Association. Louisiana Veterinary Medical Association,

Lafayette, Louisiana. (January 2015).

Mitchell, C. F., Distal Limb Lameness. Mississippi Veterinary Medical Association. Mississippi Veterinary Medical Association, Perdido

Bay, Alabama. (July 2015).

Mitchell, C. F., New Treatments for Navicular Disease. Louisiana Veterinary Medical Association. Louisiana Veterinary Medical

Association, Lafayette, Louisiana. (January 2015).

23


Pucheu-Haston, C. M., Allergic Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana

Veterinary Medical Association, Shreveport, Louisiana. (September 2015).

Pucheu-Haston, C. M., Fungal Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana


Pucheu-Haston, C. M., Parasitic Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana


Pucheu-Haston, C. M., Sarcoids. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana Veterinary Medical

Association, Shreveport, Louisiana. (September 2015).

Pucheu-Haston, C. M., Techniques in Equine Dermatology. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana


Pucheu-Haston, C. M., Therapeutics for Skin Disease in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015.

Louisiana Veterinary Medical Association. Shreveport, Louisiana. (September 2015).

Pucheu-Haston, C. M., LSU Dermatology Continuing Education Seminar Series; October 2016, “Optimizing Your Microscope for

Dermatologic Samples,” Baton Rouge, Louisiana. (October 9, 2016).

Pucheu-Haston, C. M., LSU Dermatology Continuing Education Seminar Series; October 2016, “Top Ten Reasons Otitis Treatments

Fail,” Baton Rouge, Louisiana. (October 9, 2016).

Pucheu-Haston, C. M., LSU Dermatology Continuing Education Seminar Series; October 2016, “When It’s Not Just an Abscess,” Baton

Rouge, Louisiana. (October 9, 2016).

Rademacher, N. (Presenter), LSU Abdominal Ultrasound Course, “Basic Physics, Knobology and Ultrasound Artifacts,” Universal

Ultrasound, Baton Rouge, Louisiana. (September 24, 2016).

Rademacher, N. (Presenter), LSU Abdominal Ultrasound Course, “Ultrasonography of the Abdomen - Normal Appearance,” Universal

Ultrasound, Baton Rouge, Louisiana. (September 24, 2016).

Rademacher, N. (Presenter), LSU Abdominal Ultrasound Course, “Ultrasonography of the Abdomen - Abnormal Appearance,”

Universal Ultrasound, Baton Rouge, Louisiana. (September 25, 2016).

Welborn, M. G. (Author & Presenter), Toxic Plants to Be Mindful of in the Spring. LVMA. 2015 LVMA Annual Conference. Lafayette, LA.

(January 23, 2015).

Welborn, M. (Author & Presenter), Technician Continuing Education, “Toxic Plants,” Louisiana State University SVM, Baton Rouge,

Louisiana. (March 14, 2016).

Woodward, M., Louisiana State University Dermatology Continuing Education Seminar Series, “Calcinosis Cutis/Osteoma Cutis,”

Louisiana State University SVM, Baton Rouge, Louisiana. (October 9, 2016).

Woodward, M., Louisiana State University Dermatology Continuing Education Seminar Series, “Optimizing Your Skin Biopsy,”


Woodward, M., Louisiana State University Dermatology Continuing Education Seminar Series, “Topical Therapy,” Louisiana State

University SVM, Baton Rouge, Louisiana. (October 9, 2016).

24


Other Educational Contributions

Interviews

McConnico, R. S. (2015). Hurricane Katrina: 10 years of recovery and reflection. http://www.npr.org/series/429056277/

hurricane-katrina-10-years-of-recovery-and-reflection

Annotations

McConnico, R. S. (2015). Hurricane Katrina: 10 years of recovery and reflection. http://www.npr.org/series/429056277/

hurricane-katrina-10-years-of-recovery-and-reflection

Refereed Publications

Andrews, F. M., Camacho-Luna, P., Loftin, P. G., Gaymon, G., Garza, Jr., F., Keowen, M. L., Kearney, M. T. (2015). Effects of a Pelleted

Supplement (SmartGut Ultra) on Non-Glandular Gastric Ulcer Sores and Gastric Juice pH. Equine Veterinary Education/Wiley

Publications. www.aaep.org.

Armstrong, C., Wolfe, D. F., Koziol, J., Carson, R. L. (2015). Preputial Stoma: A Novel Surgical Approach for Semen Collection in Bulls

With Phimosis Due to Preputial Stenosis; Three Cases (2007–2014). Clinical Theriogenology, 7(4), 419-423. Therio.org.

Armstrong, C. L., Koziol, J., Maxwell, H., Wolfe, D. F. (2016). Therio Question of the Month. Journal of the American Veterinary Medical

Association. avma.org

Daniel AJ, Leise BS*, Burgess BA, Morley PS, Cloniger M, and Hassel DH. 2016. Concentrations of serum amyloid A and plasma

fibrinogen in horses undergoing emergency abdominal surgery. J Emerg Vet Crit Care. 26:344-51.

Daniel AJ, McCue PM, Ferris RA, Miller C, and Leise BS*. 2015. Bilateral ovarian leiomyoma treated with standing laparoscopic

ovariectomy. Equine Vet Edu. 27:510-514.

DiGiovanni, D., Rademacher, N., Riggs, L. M., Rebecca, B., Gaschen, L. (2016). Dynamic Sonography of the Equine Metacarpo(tarso)

phalangeal Digital Flexor Tendon Sheath. Veterinary Radiology and Ultrasound, 57(6), 621-629.

Freeman, C., Mirza, M. H., Pescosolido, K., McConnico, R. S. (2015). Injuries and Outcome of Three Horses Hospitalized in the

Aftermath of Hurricane Isaac. Equine Veterinary Education, 27(6), 308-315. http://onlinelibrary.wiley.com/doi/10.1111/eve.12322/abstract

Goodman, J. D., Burns, T. A., Watts, M. R., Kelly, C. S., Leise, B. S., Schoreder, E. K., Van Eps, A., Belknap, J. K. (2016). The Effect of

Hypothermia on Influx of Mononuclear Cells in the Digital Lamellae of Horses with Oligofructose-Induced Laminitis. Vet Immunol

Immunopathol, 178, 22-28.

Koh, R. (2015). Traditional Chinese Veterinary Medicine for Challenging Disorders: Seziures. Integrative Veterinary Care Journal, 5(4),

35-40.

Leise BS*, Watts MR, Sen C, Roy S, and Belknap JK. 2015. Use of laser capture microdissection for the assessment of equine

laminar basal epithelial cells signaling in the early stages of laminitis. Equine Vet J. 47:478-488.

Madrigal, R., Andrews, F. M., Rademacher, N., McConnico, R. S., Duplantis, D., Eades, S. C. (2016). Suspected Large Pituitary Adenoma

in an 8 Year-Old Arabian Stallion. Equine Veterinary Education(Equine Vet Educ. doi:10.1111/eve.12621), 1-6. onlinelibrary.wiley.com/

25


doi/10.1111/eve.12621/epdf

Memon, M. A., Adair III, H. S., Shmalberg, J., Allweiler, S., Bryan, N., Cantwell, S., Carr, E., McConnico, R. S. (2016). Integrative

Veterinary Medical Education and Consensus Guidelines for an Integrative Veterinary Medicine Curriculum Within Veterinary

Colleges. Open Veterinary Journal.

Mitchell, C. F., Fugler, L. A., Eades, S. C. (2015). The Management of Equine Acute Laminitis. Veterinary Medicine: Research and

Reports, 6, 39.

Nelson BB, Ferris RA, McCue PM, and Leise BS*. 2015. Surgical management of atresia ani and perineal hypospadias in a miniature

donkey foal. Equine Vet Edu. 27:525-529.

Nelson BB, Edmondson EF, Frank CB, Valdes-Martinez A, and Leise BS*. 2015. Multiple skeletal metastases from a penile squamous

cell carcinoma in a horse. Equine Vet Edu. 27:119-123.

Nevarez, J. G. (2016). “Transfusiones de Sangre en Aves y Reptiles” (Blood transfusions in birds and reptiles). Consulta de Difusion

Veterinaria, 24(230), 42-44.

Queiroz, P., Doherty, T., da Cunha, A. F., Leonardi, C. (2016). Effects of Ketamine and Lidocaine in Combination on the Sevoflurane

Minimum Alveolar Concentration in Alpacas. Canadian Journal of Veterinary Research, 80(2), 141-145.

Rademacher, N. (2016). Top 5: Tips to Radiographic Diagnosis of Obstructive Foreign Bodies. Clinician’s Brief, April 2016, 89-95.

Scully, C., Lee, R. L., Pielstick, L., Medlock, J., Patton, K. M., Collins, G. H., Kutzler, M. A. (2015). Comparison of Chemical and Surgical

Vasectomy on Testicular Activity in Free-Roaming Horses (Equus Caballus). Journal of Zoo and Wildlife Medicine, 46(4).

Scientifc Abstracts

Oral Presentations

Andrews, F. M. (Author & Presenter), Equine Cushing Disease: Not Your Father’s Wooly Mammoth! Mississippi VMA Summer

Conference. Mississippi VMA. Columbus, Ohio. (July 2015).

Andrews, F. M. (Author & Presenter), Gastric Ulcers: A Pain in the Gut! Mississippi VMA Summer Conference. Mississippi VMA.

Perdido Beach, Alabama. (July 2015).

Andrews, F. M. (Author & Presenter), IgM and IgG Responses in Horses and Pony Foals After West Nile Virus and Eastern Equine

Encephalitis Vaccination. Annual ACVIM Forum. American College of Veterinary Internal Medicine. Indianapolis, Indiana. (June 2015).

Andrews, F. M. (Author & Presenter), A Pain in the Gut: Equine Gastric Ulcers. 84th Annual Conference for Veterinarians and

Veterinary Technicians. Louisiana State University SVM, Baton Rouge, Louisiana. (April 2015).

Andrews, F. M. (Author & Presenter), Gastroscopy – Technique & Interpretation. Equine Poor Performance & Rehabilitation for

Practitioners. Veterinary Professional Development (VetPD). Las Vegas, Nevada. (April 14, 2015).

Andrews, F. M. (Author & Presenter), Gastroscopy, Wet Lab. Equine Poor Performance & Rehabilitation for Practitioners. Veterinary

Professional Development (VetPD). Las Vegas, Nevada. (April 2015).

26


Andrews, F. M. (Author & Presenter), Usefulness of Haematology/Biochemistry ‘Screening’. Equine Poor Performance & Rehabilitation

for Practitioners. Veterinary Professional Development (VetPD). Las Vegas, Nevada. (April 2015).

Andrews, F. M. (Author & Presenter), Using Pulse & Lactate for Training /Rehabilitation Management. Equine Poor Performance &

Rehabilitation for Practitioners. Veterinary Professional Development (VetPD). Las Vegas, Nevada. (April 2015).

Andrews, F. M. (Author & Presenter), Case Studies in Equine Medicine. Midwest Veterinary Conference. Ohio Veterinary Medical

Association. Columbus, Ohio. (February 2015).

Andrews, F. M. (Author & Presenter), Colic: Making Decisions, Referrals, and Prognosis. Midwest Veterinary Conference. Ohio

Veterinary Medical Association. Columbus, Ohio. (February 2015).

Andrews, F. M. (Author & Presenter), Colonic Ulcers: A Pain in the Hindgut! Midwest Veterinary Conference. Ohio Veterinary Medical


Andrews, F. M. (Author & Presenter), Equine Cushing Disease: Not Your Father’s Wooly Mammoth! Midwest Veterinary Conference.

Ohio Veterinary Medical Association. Columbus, Ohio. (February 2015).

Andrews, F. M. (Author & Presenter), Gastric Ulcers: A Pain in the Gut! Midwest Veterinary Conference. Ohio Veterinary Medical


Andrews, F. M. (Author & Presenter), Gastric Ulcers: Relieving the pain! Midwest Veterinary Conference. Ohio Veterinary Medical

Association, Columbus, Ohio. (February 2015).

Andrews, F. M. (Author & Presenter), An Update on Equine Gastric Ulcer Syndrome. LVMA Annual Winter Meeting. Lafayette, LA.

(January 2015).

Andrews, F. M. (Author & Presenter), Colic: A Model for Surgery and Survival. LVMA Annual Winter Meeting. Lafayette, LA. (January

2015).

Andrews, F. M. (Author & Presenter), Equine Gastric Ulcer Syndrome: What about supplements? LVMA Annual Winter Meeting.

Lafayette, LA. (January 2015).

Andrews, F. M., 14th Annual Mid-Atlantic Nutrition Conference, “New Advances in Treating Gastric Ulcers in Performance Horses,”

Maryland Feed Industry Council, Hunt Valley, Maryland. (March 24, 2016).

Andrews, F. M., 77th Minnesota Nutrition Conference, “Equine Gastric Ulcers: Prevention and Treatment,” University of Minnesota,

Prior Lake, Minnesota. (September 22, 2016).

Andrews, F. M., 85th LSU SVM Annual Conference for Veterinarians and Veterinary Technicians, “Am I Giving my Horse a Stomach

Ulcer?” Louisiana State University SVM, Baton Rouge, Louisiana. (April 16, 2016).

27


Andrews, F. M. (Author & Presenter), 2015–2016 Southern States Advanced Equine Feedmaster Program, “Equine Gastric Ulcer

Syndrome and Colonic Ulcers,” Southern States Feed Company, Glen Allen, Virginia. (February 2, 2016).

Andrews, F. M. (Author & Presenter), BIVI CE Meeting at the American Rodeo, “Viral Respiratory Disease in Horses,” Boehringer

Ingelheim Vetmedica, Arlington, Texas. (February 28, 2016).

Andrews, F. M. (Author & Presenter), BIVI Veterinary Meeting, “Equine Gastric Ulcer Syndrome: Updates on Diagnosis and

Treatment,” Boehringer Ingelheim Vetmedica, Bozeman, Montana. (September 8, 2016).

Andrews, F. M. (Author & Presenter), BIVI Veterinary Meeting, “Equine Protozoal Myeloencephalitis: Updates on Diagnosis and

Treatment,” Boehringer Ingelheim Vetmedica, Bozeman, Montana. (September 8, 2016).

Andrews, F. M., EquiDay 2016, “Are You Giving Your Horse Stomach Ulcers?” Student Chapter AAEP at Louisiana State University,

Baton Rouge, Louisiana. (March 12, 2016).

Andrews, F. M., Camacho, P., Garza, Jr., F., Keowen, M. L., 62nd Annual AAEP Convention, “IgM and IgG Response of Horses and

Pony Foals after Vaccination for West Nile Virus and Eastern Equine Encephalitis,” American Association of Equine Practitioners,

Orlando, Florida. (December 6, 2016).

Andrews, F. M. (Author & Presenter), Odoi, A. (Author), Sommardahl, C. S. (Author), International Equine Infectious Disease

Conference X, “Incidence of Equine Protozoal Myeloencephalitis (EPM) in Veterinary Teaching Hospitals,” Gluck Equine Research

Center, University of Kentucky, Buenos Aires, Argentina. (April 5, 2016).

Andrews, F. M. (Author & Presenter), Shannon, D. (Author), Lyle, S. K. (Author), Keowen, M. L. (Author), Keene, R. (Author), Grubbs,

S. (Author), Roy, A. F. (Author), International Equine Infectious Disease Conference X, “IgM and IgG Responses in Horses and Pony

Foals after Vaccination for West Nile Virus and Eastern Equine Encephalitis,” Gluck Equine Research Center, University of Kentucky,

Buenos Aires, Argentina. (April 5, 2016).

Arana, N. (Author & Presenter), Andrews, F. M. (Author), Annual ACVIM Forum, The Effect of pH on Large Intestinal Ion Transport and

Transepithelial Resistance in Suspected Insulin Resistance Horses. American College of Veterinary Internal Medicine. Indianapolis,

Indiana. (June 2015).

Armstrong, C. L. (Author & Presenter), Koziol, J. (Author & Presenter), BSE/eBSE and Lameness in Bulls. Therio Conference and

Symposia. Society for Theriogenology. San Antonio, Texas. (August 8, 2015).

Armstrong, C., Alabama Veterinary Medical Association 25th Annual Food Animal Conference, “Bull Breeding Soundness Exam:

Morphologic Slide Preparation and Assessment,” ALVMA, Columbiana, Alabama. (February 21, 2016).

Armstrong, C., Integrated Approach for Managing Diseases and Parasites in Small Ruminants, “Major Diseases of Small Ruminants

and Their Prevention, Control, and Treatment Strategies,” Tuskegee University, Tuskegee, Alabama. (October 28, 2016).

28


Armstrong, C., Louisiana Cattlemen’s Annual Meeting, “Bull Breeding Soundness Examination,” Louisiana Cattlemen’s Association,

Houma, Louisiana. (January 9, 2016).

Armstrong, C. L., Lunch and Science Seminar Series, “Detection of Tritrichomonas foetus in Bovine Semen with Centrifugation and

PCR,” Louisiana State University SVM, Baton Rouge, Louisiana. (November 18, 2016).

Armstrong, C. L. (Presenter), Small Ruminant Field Day, “Small Ruminant Reproductive Performance,” Louisiana State University SVM,


Armstrong, C., Washington Parish Cattlemen’s Association Summer Meeting, “Veterinary Feed Directive,” Washington Parish

Cattlemen’s Association, Louisiana State University Southeast Dairy Unit, Franklinton, Louisiana. (June 16, 2016).

Camacho, P. (Author & Presenter), Andrews, F. M. (Author), Gaschen, L., Markle, M. (Other), Keowen, M. L. (Author), Garza, Jr., F.

(Author), Kearney, M. T., Storey, E. S., 62th Annual AAEP Convention, “Effects of 1% Ophthalmic Atropine Sulfate Solution on the

Gastrointestinal Motility and Transit Time in Healthy Horses,” American Association of Equine Practitioners, Orlando, Florida.

(December 6, 2016).

Carter, R. T., Louisiana State University Alumni Homecoming CE, “Underlying Disorders That Complicate Ocular Health,” Louisiana

State University SVM, Baton Rouge, Louisiana. (October 15, 2016).

Carter, R. T., North American Veterinary Conference, “Glaucoma Medications: What Drugs to Choose?” (January 18, 2016).

Carter, R. T., North American Veterinary Conference, “Management of Ocular Emergencies: Case Discussion (Masterclass).” (January

17, 2016).

Carter, R. T., North American Veterinary Conference, “Your Ophthalmoscope: How to Get the Most From It.” (January 18, 2016).

Chapman, A. M. (Author & Presenter), Equine Medical Emergencies. Annual Conference for Veterinarians and Technicians. Louisiana

State University SVM. Baton Rouge, Louisiana. (April 2015).

Chapman, A. M., The Fat Horse: Update on Equine Metabolic Syndrome. Partnering for Large Animal Health Educational Series.

Louisiana State University SVM. Baton Rouge, Louisiana. (August 2015).

Chapman, A. M., Equi-Day, “Equine Vaccinations,” Louisiana State University SVM SCAAEP, Baton Rouge, Louisiana. (March 12, 2016).

Chapman, A. M. (Author & Presenter), Annual Meeting, “Understanding Equine Fluid Therapy,” Louisiana Veterinary Medicine

Association, Shreveport, Louisiana. (January 31, 2016).

Cremer, J., BRAVMA, “Hemoabdomen,” Baton Rouge, Louisiana. (April 12, 2016).

da Cunha, A. F., PROSSUI, “Trajetoria de um Profissional Graduado no Setor Palotina que atua na Docência em Louisiana State

University,” Federal University of Parana, Brazil. (May 31, 2016).

29


De Caro Carella, C., Continuing Education for Technicians, “Moving Into the Future with the Digital Anesthetic Record,” Louisiana

State University SVM, Baton Rouge, Louisiana. (December 5, 2016).

Dirikolu, L. (Author & Presenter), Waller, P., Waguespack, M. L., Andrews, F. M., Keowen, M. L., Gaunt, S. D., 21st International

Conference on Racing Analysts and Veterinarians, “The Effect of Sodium Bicarbonate and Validation of Beckman Coulter AU680

Analyzers for Measuring Total Carbon Dioxide (TC02) Concentration Horse Serum,” Racing Analysts and Veterinarians, Montevideo,

Uraguay. (October 15, 2016).

Eades, S. C., Equine Laminitis. Partnering for Large Animal Health Education Series. Equine Health Studies Program. Louisiana State

University SVM. (August 2015).

Eades, S. C., Laminitis Induction Via Carbohydrate Overload and Euglycemic Hyperinsulinemic Clamp Technique and the Effects of

Pentoxifylline on Lameness. The Ohio State University Department Seminar. The Ohio State University. (June 2015).

Gaschen, L., EVDI 2016 Congress, “Diagnosing Intestinal Obstructions Tips You Need to Know,” Wroclaw, Poland. (September 4,

2016).

Gaschen, L., EVDI 2016 Congress, “Making Sense of Lung Patterns How to Develop an Action Plan,” Wroclaw, Poland. (September 4,

2016).

Gaschen, L., LSU Annual Conference, “Making Sense of Lung Patterns How to Develop an Action Plan,” LSU SVM, Baton Rouge,

Louisiana. (April 16, 2016).

Gaschen, L., WSAVA, “How I do Tissue Sampling,” Cartegna, Colombia. (September 30, 2016).

Gaschen, L., WSAVA, “How I use Compression Radiography,” Cartegna, Colombia. (September 30, 2016).

Gaschen, L., WSAVA, “Respiratory Distress: The Airway,” Cartegna, Colombia. (September 30, 2016).

Gaschen, L., WSAVA, “Respiratory Distress: The Lung,” Cartegna, Colombia. (September 30, 2016).

Granger, L. A., U-Learn Ultrasound, “Abnormal: Gastrointestinal Tract,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Abnormal: Liver and Spleen,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Abnormal: Lymph Nodes and Mesentery,” Universal Ultrasound and LSU, Louisiana State


Granger, L. A., U-Learn Ultrasound, “Abnormal: Urogenital Tract,” Universal Ultrasound and LSU, Louisiana State University SVM,


30


Granger, L. A., U-Learn Ultrasound, “Basic Physics of Ultrasound,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Normal Organ Appearance,” Universal Ultrasound and LSU, Louisiana State University SVM,


Granger, L. A., U-Learn Ultrasound, “Patient Preparation and Tissue Sampling,” Universal Ultrasound and LSU, Louisiana State


Granger, L. A., U-Learn Ultrasound, “Ultrasound Equipment,” Universal Ultrasound and LSU, Louisiana State University SVM, Baton


Koh, R., Acupuncture: Evidence-Based and Clinical Applications. China Acupuncture Course. Chi Institute of Chinese Medicine.

Guangzhou, China. (May 2015).

Koh, R., Intro to Integrative Medicine. Louisiana State University Integrative Medicine Club Meeting. Louisiana State University

Integrative Medicine Club. Baton Rouge, Louisiana. (September 2015).

Koh, R., Integrative Medicine: Acupuncture and Its Integration into Conventional Medicine. Oklahoma State University Grand Seminar.

Oklahoma State University SVM. Oklahoma. (October 2015).

Koh, R., Chinese Herbal Medicine and Food Therapy in Veterinary Practice. Oklahoma State University Integrative Medicine Club

Meeting. Oklahoma State University Integrative Medicine Club. Oklahoma. (October 2015).

Koh, R., Integrative Medicine - Moving Health Care In A New Direction. South West Veterinary Conference. Fort Worth, Texas.

(September 2015).

Koh, R., Osteoarthritis: Thinking Beyond NSAIDs—An Integrative Approach. South West Veterinary Conference. Fort Worth, Texas.

(September 2015).

Koh, R. (Presenter), Hongkong Veterinary Seminar, “Rehabilitation for Intervertebral Disc Disease,” Hongkong Veterinary Medical

Association, Hongkong, China. (May 24, 2016).

Koh, R. (Presenter), Hongkong Veterinary Seminar, “Traditional Chinese Veterinary Medicine for Intervertebral Disc Disease,”

Hongkong Veterinary Medical Association, Hongkong, China. (May 24, 2016).

Koh, R. (Presenter), Integrative Medicine Club Lunch and Learn, “Acupuncture for Clinical Practice,” North Carolina State University

College of Veterinary Medicine, Raleigh, North Carolina. (October 25, 2016).

Koh, R. (Presenter), Grand Rounds Seminar, “Improving Neurologic and Orthopedic Outcomes with Rehabilitation,” National Taiwan

University College of Veterinary Medicine, Taipei City, Taiwan. (September 6, 2016).

31


Koh, R. (Presenter), Grand Rounds Seminar, “Improving Neurologic and Orthopedic Outcomes with Rehabilitation,” National Chung

Hsing University College of Veterinary Medicine, Taichung City, Taiwan. (September 2, 2016).

Koh, R. (Presenter), Grand Rounds Seminar, “Improving Neurological Patient Outcomes with Rehabilitation,” China Agricultural

University College of Veterinary Medicine, Guangzhou, China. (May 19, 2016).

Koh, R. (Presenter), LVMA Winter Meeting, “Acupuncture - Science-Based Medicine,” LVMA, Shreveport, Louisiana. (January 29, 2016).

Koh, R. (Presenter), LVMA Winter Meeting, “Integrative Medical Approach to Common Clinical Problems in Small Animals,” LVMA,

Shreveport, Louisiana. (January 29, 2016).

Koh, R. (Presenter), Moscow Veterinary Congress, “Intro to Traditional Chinese Veterinary Medicine,” Moscow Veterinary Medical


Koh, R. (Presenter), Moscow Veterinary Congress, “Most Researched Acupoints and their clinical applications,” Moscow Veterinary

Medical Association, Moscow, Russia. (April 24, 2016).

Koh, R. (Presenter), Moscow Veterinary Congress, “The Science behind Veterinary Acupuncture,” Moscow Veterinary Medical


Koh, R. (Presenter), Moscow Veterinary Congress, “Understanding Acupuncture And How It Could Benefit Your Patients,” Moscow

Veterinary Medical Association, Moscow, Russia. (April 24, 2016).

Leise, B. S. (Author & Presenter), Custis, J. T., Landolt, G. A., LaRue, S. M., Use of Electronic Brachytherapy for Adjunctive Therapy in

the Treatment of Equine Neoplasia. ACVS Symposium. ACVS. Nashville, Tennessee. (October 2015).

Leise, B. (Author & Presenter), Louisiana State University -SCAAEP Equi-Day, “First Aid for Horses,” LSU-SCAAEP, Baton Rouge,

Louisiana. (March 2016).

Leise, B. S. (Author & Presenter), Louisiana State University SVM Annual Conference– Technician’s Forum, “Equine Wound

Management,” Baton Rouge, Louisiana. (April 2016).

Leise, B., Louisiana Therapeutic Riding Association Annual Conference, “Equine Laminitis,” Baton Rouge, LA. (January 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Equine Wounds: Case Discussions,” Orlando, Florida.

(January 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Regional Limb Perfusion in the Horse: Update on Use,”

Orlando, Florida. (January 2016).

Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Wounds Associated with Synovial Structures: Diagnosis

and Management,” Orlando, Florida. (January 2016).

32


Leise, B. S. (Author & Presenter), North American Veterinary Conference, “Wounds of the Chest and Abdomen,” Orlando, Florida.

(January 2016).

Leise, B. (Author & Presenter), Miller, N., Moorman, V., Bass, L., Pittman, S., Rucker, A., Redden, R., AAEP 62nd Annual Convention,

“Assessment of Digital Venograms in Non-Laminitic Horses,” American Association of Equine Practitioners, Orlando, Florida.

(December 2016).

Liu, A. (Author), Haque, M. (Author), Andrews, F. M. (Author & Presenter), Roy, A. F. (Author), Kousoulas, K. G. (Chair), International

Equine Infectious Disease Conference X, “A Recombinant Fusion Protein Consisting of West Nile Virus Envelope Domain III Fused

in-frame with Equine CD40 Ligand Induces Anti-viral Immune Responses in Horses,” Gluck Equine Research Center, University of

Kentucky, Buenos Aires, Argentina. (April 5, 2016).

Lopez, M. J. (Author & Presenter), An Alternate Funding Universe: Foundations and Industry. Louisiana State University SVM

Graduate Student Organization. Louisiana, Baton Rouge. (August 2015).

Lopez, M. J. (Author & Presenter), Fargason, C. (Author), Kelly, L. (Author), Del Piero, F. (Author), Dasa, V. (Author), King, A. (Author),

Stem Cells Augment Demineralized Bone Matrix. American College of Veterinary Surgeons Summit. Nashville, Tennessee. (October

2015).

Lopez, M. J. (Author & Presenter), Fargason, C. (Author), Kelly, L. (Author), Del Piero, F. (Author), Dasa, V. (Author), King, A. (Author),

Stem Cells Augment Demineralized Bone Matrix. International Federation for Adipose Therapeutics and Science Meeting. New

Orleans, Louisiana. (November 2015).

Lopez, M. J. (Author & Presenter), Stem Cells: Breaking News from the Benchtop. Merial Summer Scholars Program. Louisiana State

University SVM. Baton Rouge, Louisiana. (June 2015).

Lopez, M. J. (Author & Presenter), Jarazo, J. (Author), Fargason, C. (Author), Bondioli, K. (Author & Presenter), Synthetic mRNA to

Dedifferentiate Equine Adult Multipotent Stromal Cells. International Federation for Adipose Therapeutics and Science Meeting. New

Orleans, Louisiana. (November 2015).

Lopez, M. J. (Author & Presenter), Jarazo, J. (Author), Fargason, C. (Author), Bondioli, K. (Author), Synthetic mRNA to Dedifferentiate

Equine Adult Multipotent Stromal Cells. North American Veterinary Regenerative Medicine Conference. Monterey, California. (June

2015).

Lopez, M. J., 39th Annual Louisiana Veterinary Medical Association Equine Seminar, “Platelet Rich Plasma and Stem Cells,”

Shreveport, Louisiana. (September 25, 2016).

Lopez, M. J., Annual Meeting of Louisiana Professional Association of Therapeutic Horsemanship, “Platelet Rich Plasma to Alleviate

Signs of Osteoarthritis in Horses,” Annual Meeting of Lo, Baton Rouge, Louisiana. (January 31, 2016).

Lopez, M. J. (Author & Presenter), Johnson & Johnson Innovation Meeting, “Tesa Medical GrabTek Technology,” New Orleans,

Louisiana. (September 19, 2016).

33


Lopez, M. J., “Of Mice and Men (and Everything in Between): Imaging for Translational Research,” Louisiana State University Imaging

Symposium: Biomedical, Materials, and Computational, Baton Rouge, Louisiana. (April 23, 2016).

Lopez, M. J. (Author & Presenter), Duan, W. (Author), Haque, M. (Author), Kearney, M. T. (Author), Gimble, J. (Author), International

Federation for Adipose Therapeutics and Science Annual Meeting, “Collagen and Hydroxyapatite Scaffolds Stimulate Distinct

Osteogenesis Pathways.” (November 18, 2016).

Magee, A., SVM Annual Conference, “ECG Interpretation for Technicians,” Louisiana State University SVM, Baton Rouge, Louisiana.

(April 2016).

Magee, A., BRAVMA monthly meeting, “Interpreting ECGs,” BRAVMA, Baton Rouge, Louisiana. (January 2016).

McCauley, C. T., Suspensory Ligament Disease. Partnering for Large Animal Health Education Series. Louisiana State University SVM.

Baton Rouge, Louisiana. (August 2015).

McCauley, C. T., Suspensory Ligament Disease. Louisiana Veterinary Medical Association Winter Meeting. Louisiana Veterinary

Medical Association, Lafayette, Louisiana. (January 2015).

McCauley, C. T. (Presenter), 2016 Louisiana Society or Radiological Technology Annual Meeting, “Application of Diagnostic Imaging

Technology to Veterinary Medicine,” Louisiana Society of Radiological Technology, Baton Rouge, Louisiana. (July 9, 2016).

McConnico, R. S. (Author & Presenter), Walker, N. (Author), Navarre, C. B. (Author), Biosecuritry Considerations for Equine Emergency

Sheltering. Katrina & Rita Symposium: A Decade of Research & Response. Louisiana State University Office of Research and

Economic Development. Baton Rouge, Louisiana. (August 2015).

McConnico, R. S., Equine Medicine ‘911’.Western Veterinary Conference. Las Vegas, Nevada. (February 2015).

McConnico, R. S., Experiential Learning in Community Disaster Response. International Disaster Conference and Expo. New Orleans,

Louisiana. (February 2015).

McConnico, R. S. (Author & Presenter), Wolfson, W. (Author), Mirza, M. H. (Author), Taboada, J. (Author), Experiential Learning in

Disaster Response for Veterinary Students and Veterinarians. Katrina and Rita Symposium. Louisiana State University Office of

Research and Development. Baton Rouge, Louisiana. (July 2015).

McConnico, R. S., Horse Hot Zone: Care and Management of Equine Infectious Disease Cases. Western Veterinary Conference. Las

Vegas, Nevada. (February 2015).

McConnico, R. S. (Author & Presenter), Freeman, C. (Author), Pescosolido, K. (Author), Mirza, M. H. (Author), Injuries and Outcome

of Three Horses Hospitalized in the Aftermath of Hurricane Isaac. Katrina & Rita Symposium: A Decade of Research & Response.

Louisiana State University Office of Research and Economic Development. Baton Rouge, Louisiana. (August 2015).

McConnico, R. S., Large Animal Technical Emergency Rescue. Katrina Commemorative Animal Responder Boot Camp. LSART-LVMA-

ASPCA-IFAW-NASAAEP-AHA-RR. Baton Rouge, Louisiana. (August 2015).

34


McConnico, R. S., Preventing Pestilence. Western Veterinary Conference. Las Vegas, Nevada. (February 2015).

McConnico, R. S., The Veterinarian’s Role in Cases of Equine Cruelty. Western Veterinary Conference. Las Vegas, Nevada. (February

2015).

McConnico, R. S. (Author & Presenter), Animal Welfare Symposium for Veterinary Students, “The Impact of Equine Welfare Issues on

the Animal,” Humane Society Veterinary Medical Association, Louisiana State University SVM, Baton Rouge, Louisiana. (November 12,

2016).

McConnico, R. S. (Author & Presenter), National Alliance of State Animal and Agriculture Emergency Programs, “Biosecurity

Considerations in Equine Emergency Sheltering,” Texas A & M, College Station, Texas. (May 17, 2016).

McConnico, R. S. (Author & Presenter), Rashmir, A. (Author & Presenter), 8th World Congress of Veterinary Dermatology, “The Use of

Serine Protease Inhibitors in the Treatment of Equine Pemphigus Foliaceus,” World Association of Veterinary Dermatology, Bordeaux,

France. (June 3, 2016).

McConnico, R. S., First Defense Conference & Expo, “Title: Experiential Learning in Animal Disaster Response: The Louisiana

Experience 2004-2015,” Centers for Domestic Preparedness, Louisville, Kentucky. (March 18, 2016).

Mirza, M. H., Large Animal Handling and Rope Tying. (September 2015).

Mirza, M. H., Large Animal Rescue. LSART Boot Camp. 2015LDAF,LSART,IFAW, NASAAEP,USDA and People of Humane Society.

(August 2015).

Mirza, M. H., Large Animal Rescue Techniques. LDAF. (September 2015).

Mitchell, C. F., A Diagnostic Approach to Lower Limb Lameness. Mississippi Veterinary Medical Association. Perdido Bay, Alabama.

(July 2015).

Mitchell, C. F., An Update on Navicular Disease. Louisiana Veterinary Medical Association. Lafayette, Louisiana. (January 2015).

Mitchell, C. F., Distal Limb Lameness. Mississippi Veterinary Medical Association. Perdido Bay, Alabama. (July 2015).

Mitchell, C. F., New Treatments for Navicular Disease. Louisiana Veterinary Medical Association, Lafayette, Louisiana. (January 2015).

Paccamonti, D. L., Diagnostic Techniques for Mare Infertility: How Times Have Changed. Corso de Diplomado en Reproducion en

Equinos. AMMVEE. Guadalajara, Mexico. (March 2015).

Paccamonti, D. L., Uterine Biopsy: Time to Re-evaluate? Corso de Diplomado en Reproducion en Equinos. AMMVEE. Guadalajara,


35


Paccamonti, D. L., Uterine Therapy for the Infertile Mare. Corso de Diplomado en Reproducion en Equinos. AMMVEE. Guadalajara,


Paccamonti, D. L., 9th International Congress on Equine Reproductive Medicine, “Ovulatory Failure: Contributing Factors and

Possible Management Strategies.” (January 2016).

Paccamonti, D. L. (Presenter), Len, J. A. (Author), McDowall, M. (Author), Anastasie, M. (Author), Kleeman, D. (Author), International

Symposium on Equine Embryo Transfer, “Glucose Uptake and Lactate Production of Equine Cumulus-Oocyte Complexes During In

Vitro Maturation,” Gent, Belgium. (June 2016).

Pucheu-Haston, C. M., Allergic Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana

Veterinary Medical Association. Shreveport, Louisiana. (September 2015).

Pucheu-Haston, C. M, Fungal Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana


Pucheu-Haston, C. M, Parasitic Skin Diseases in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana


Pucheu-Haston, C. M., Sarcoids. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana Veterinary Medical

Association. Shreveport, Louisiana. (September 2015).

Pucheu-Haston, C. M., Techniques in Equine Dermatology. Louisiana Veterinary Medical Association Equine Seminar 2015. Louisiana


Pucheu-Haston, C. M., Therapeutics for Skin Disease in the Horse. Louisiana Veterinary Medical Association Equine Seminar 2015.

Louisiana Veterinary Medical Association. Shreveport, Louisiana. (September 2015).

Pucheu-Haston, C. M., Louisiana State University Dermatology Continuing Education Seminar Series; October 2016, “Optimizing Your

Microscope for Dermatologic Samples,” Baton Rouge, Louisiana. (October 9, 2016).

Pucheu-Haston, C. M., Louisiana State University Dermatology Continuing Education Seminar Series; October 2016, “Top Ten

Reasons Otitis Treatments Fail,” Baton Rouge, Louisiana. (October 9, 2016).

Pucheu-Haston, C. M., Louisiana State University Dermatology Continuing Education Seminar Series; October 2016, “When It’s Not

Just an Abscess,” Baton Rouge, Louisiana. (October 9, 2016).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Antibiotic Resistant Skin Infections: What

Antibiotics to Use Now?” North American Veterinary Community, Orlando, Florida. (January 17, 2016).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Better Skin Biopsies: How to Get the Most From

Your Samples,” North American Veterinary Community, Orlando, Florida. (January 17, 2016).

36


Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Optimizing Your Microscope for Dermatologic

Samples,” North American Veterinary Community, Orlando, Florida. (January 17, 2016).

Pucheu-Haston, C. M., North American Veterinary Community Conference (NAVC), “Medical Management of Pruritus: The Good, the

Bad and the Ugly,” North American Veterinary Community, Orlando, Florida. (January 16, 2016).

Pucheu-Haston, C. M., Whole Horse Wellness Seminar, “Techniques in Equine Dermatology,” Kinetic Vet, Nashville, Tennessee. (July

23, 2016).

Rademacher, N. (Presenter), Louisiana State University Abdominal Ultrasound Course, “Basic Physics, Knobology and Ultrasound

Artifacts,” Universal Ultrasound, Baton Rouge, Louisiana. (September 24, 2016).

Rademacher, N. (Presenter), Louisiana State University Abdominal Ultrasound Course, “Tissue Sampling - FNA and Biopsy Basics,”

Universal Ultrasound, Baton Rouge, Louisiana. (September 25, 2016).

Rademacher, N. (Presenter), Louisiana State University Abdominal Ultrasound Course, “Ultrasonography of the Abdomen - Abnormal

Appearance,” Universal Ultrasound, Baton Rouge, Louisiana. (September 25, 2016).

Rademacher, N. (Presenter), Louisiana State University Abdominal Ultrasound Course, “Ultrasonography of the Abdomen - Normal

Appearance,” Universal Ultrasound, Baton Rouge, Louisiana. (September 24, 2016).

Rademacher, N. (Author & Presenter), NAVC-North American Veterinary Community, “FLASH Ultrasound of the Abdomen,” Orlando,


Riggs, L. M., Veterinary Continuing Education (CVC), “Acute Wounds: When to Worry,” CVC, Kansas City, Missouri. (August 28, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Chronic Wounds,” CVC, Kansas City, Missouri. (August 28, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Colic in Foals,” CVC, Kansas City, Missouri. (August 28, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Dealing with Thoracic and Abdominal Wounds,” CVC, Kansas City, Missouri.

(August 29, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Exercising Upper Airway Endoscopy,” CVC, Kansas City, Missouri. (August 29,

2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Sedation and Local Anesthesia for Standing Surgery,” CVC, Kansas City,

Missouri. (August 29, 2016).

Riggs, L. M., Veterinary Continuing Education (CVC), “Standing Surgical Procedures,” CVC, Kansas City, Missouri. (August 29, 2016).

37


Riggs, L. M., Veterinary Continuing Education (CVC), “Updates on Treating Upper Airway Disease,” CVC, Kansas City, Missouri.

(August 29, 2016).

Riggs, L. M., North American Veterinary Conference, “Acute Wounds: When to be Concerned,” NAVC, Orlando, Florida. (January 17,

2016).

Riggs, L. M., North American Veterinary Conference, “Field Anesthesia: The Cliff’s Notes,” NAVC, Orlando, Florida. (January 17, 2016).

Riggs, L. M., North American Veterinary Conference, “Field Treatments for Colic: More Options Than You Think,” NAVC, Orlando,


Riggs, L. M., North American Veterinary Conference, “Never Too Young to Colic,” NAVC, Orlando, Florida. (January 17, 2016).

Scully, C., Comparison of Chemical and Surgical Vasectomy on Testicular Activity in Free-Roaming Stallions. Society for

Theriogenology. San Antonio, Texas. (July 2015).

Sones, J., 2016 Experimental Biology, “Artificial Synchronization of Ovarian Hormones in Early Pregnancy Improves Adverse

Pregnancy Outcomes Associated with Preeclampsia in the BPH/5 Mouse Model,” American Physiological Society, San Diego,

California. (April 2016).

Sones, J. L. (Author & Presenter), Academic Development, Reproductive Endocrinology & Women’s Health Research Program,

“Preeclampsia: Inflammation, Ovarian Hormone Signaling, and Adiposity,” Pennington Biomedical Research Center, Baton Rouge,

Louisiana. (September 2016).

Sones, J. L. (Author & Presenter), Cornell University 2nd Reproductive Genomics Seminar, “The Role of MicroRNAs in Defective

Perimplantation Signaling Observed in the Spontaneous BPH/5 Mouse Model of Preeclampsia,” NIH, Ithaca, New York. (April 2016).

Sones, J. L. (Author & Presenter), Louisiana Biomedical Collaborative Research Program, “The Role of Maternal Adipose Tissue in the

Preeclamptic-Like BPH/5 Mouse,” Louisiana State University, Baton Rouge, Louisiana. (September 2016).

Sones, J. L., Lunch and Science seminar series, “BPH/5, a Model of Adverse Pregnancy Outcomes in Women,” Louisiana State

University SVM, Baton Rouge, Louisiana. (March 2016).

Sones, J., SCAAEP EquiDay, “So You Wanna Breed Your Mare?” Student Chapter of the American Association of Equine Practitioners,

Baton Rouge, Louisiana. (March 2016).

Welborn, M. G. (Presenter), Common Toxic Plants Affecting Small and Large Animals. Southwest Veterinary Symposium. Ft. Worth,

Texas. (September 2015).

Welborn, M. G. (Presenter), Update on Zoonotic Diseases. Southwest Veterinary Symposium. Ft. Worth, Texas. (September 2015).

Welborn, M. G. (Author & Presenter), Toxic Plants to Be Mindful of in the Spring. 2015 LVMA Annual Conference. LVMA. Lafayette,

Louisiana. (January 2015).

38


Welborn, M. G. (Author & Presenter), Louisiana Cattleman’s Annual Convention, “Toxic Plants to Be Mindful of in the Spring,” Louisiana

Cattleman’s Association, Houma, Louisiana. (January 9, 2016).

Welborn, M. G. (Presenter), Louisiana State University/Southern Univ. Small Ruminant Field Day, “Drug Use & Off-Label Issues

Concerning Small Ruminant Owners,” Louisiana State University SVM & Southern University, Louisiana State University SVM, Baton


Welborn, M. G. (Author & Presenter), Technician Continuing Education, “Toxic Plants,” Louisiana State University SVM, Baton Rouge,

Louisiana. (March 14, 2016).

Woodward, M., Louisiana State University Dermatology Continuing Education Seminar Series, “Calcinosis Cutis/Osteoma Cutis,”


Woodward, M., Louisiana State University Dermatology Continuing Education Seminar Series, “Optimizing Your Skin Biopsy,”


Woodward, M., Louisiana State University Dermatology Continuing Education Seminar Series, “Topical Therapy,” Louisiana State

University SVM, Baton Rouge, Louisiana. (October 9, 2016).

Poster Presentations

Ainsworth, S. (Presenter), Keowan, M. (Other), Fletcher, J. M. (Other), Kearney, M. T. (Other), Chapman, A. M. (Author), Evaluation of

Adrenocorticotropin Hormone Concentrations in Response Varying Doses of Thyrotropin Releasing Hormone in Normal Horses.

Louisiana Undergraduate Research Conference. Louisiana State University Office of Strategic Initiatives. Baton Rouge, Louisiana.

(November 2015).


Adrenocorticotropin Hormone Concentrations in Response Varying Doses of Thyrotropin Releasing Hormone in Normal Horses. Phi

Zeta Research Day. Louisiana State University, SVM. Baton Rouge, Louisiana. (September 2015).


Adrenocorticotropin Hormone Concentrations in Response Varying Doses of Thyrotropin Releasing Hormone in Normal Horses.

Louisiana State University Summer Undergraduate Research Forum. Louisiana Biomedical Research Network. Baton Rouge,

Louisiana. (July 2015).

Andrews, F. M. (Author & Presenter), Cruz-Sanabia, J. (Author), Validation of a Multivariable Colic Predition Model. Annual ACVIM

Forum. American College of Veterinary Internal Medicine. Indianapolis, Indiana. (June 2015).

Armstrong, C. L. (Author & Presenter), Wolfe, D. F. (Author), Passler, T. (Author), Edmondson, M. (Author), Joiner, K. (Author), Carson,

R. L. (Author), Rodning, S. P. (Author), The Detection of Tritrichomonas Foetus in Bovine Semen with Centrifugation and PCR. 2015

Therio Conference and Symposia. Society for Theriogenology. San Antonio, Texas. (August 2015).

39


DiGiovanni, D. (Author & Presenter), Rademacher, N. (Author), Riggs, L. M. (Author), Baumruck, R. (Author), Gaschen, L. (Author),

Dynamic Sonography of The Equine Fetlock. ACVS Surgery Summit 2015. American College of Veterinary Surgery. Knoxville,

Tennessee. (October 2015).

DiGiovanni, D. L. (Author & Presenter), Rademacher, N., Riggs, L. M. (Author), Baumruck, R., Gaschen, L. (Author), Dynamic

Sonography of the Equine Fetlock. Louisiana State University SVM Phi Zeta Research Day. Merck Merial Summer Student Research.

Baton Rouge, Louisiana. (September 2015).

Duan, W. (Author & Presenter), Lopez, M. J. (Author), Bioscaffolds Direct Adult Equine Multipotent Stromal Cell Osteogenesis.

Louisiana State University SVM Phi Zeta Research Day. (September 2015).

Duan, W. (Author & Presenter), Mirza, M. H., Lopez, M. J., LSU SVM Phi Zeta Research Day, “Equine Adipose Derived Multipotent

Stromal Cells Expressing Major Histocompatibility Complex II Have Multipotent Capacity,” Baton Rouge, Louisiana. (September 28,

2016).

Gillett, A. (Author & Presenter), McNulty, M. A. (Other), Goupil, B. (Other), Mitchell, C. F. (Other), Effects of Tiludronate on Bone Growth

and Remodeling in Young Horses. Louisiana State University SVM Phi Zeta Research Day. (September 2015).

Gillett, A. (Author & Presenter), McNulty, M. A. (Other), Goupil, B. (Other), Mitchell, C. F. (Other), Effects of Tiludronate on Bone Growth

and Remodeling in Young Horses. Merial/NIH Symposium at UC Davis. California. (August 2015).

Jarazo, J. (Author), Fargason, C. (Author), Bondioli, K. (Author), Lopez, M. J. (Author & Presenter), Synthetic mRNA to Dedifferentiate

Equine Adult Multipotent Stromal Cells. International Federation for Adipose Therapeutics and Science Meeting. New Orleans,

Louisiana. (November 2015).

Jarazo, J. (Author), Bondioli, K. (Author), Lopez, M. J. (Author & Presenter), Orthopaedic Research Society Annual Meeting, “Synthetic

mRNA to Dedifferentiate Equine Adult Multipotent Stromal Cells,” Orlando, Florida. (March 7, 2016).

Leisinger, C., Pinto, C. R., Love, C. C., Paccamonti, D. L., Annual Phi Zeta Research Emphasis Day, “Effects of Repeated Partial Thaw

and Refreeze on Post Thaw Parameters of Stallion Semen,” Louisiana State University SVM, Baton Rouge, Louisiana. (September

2016).

Malik, C. (Presenter), Keowan, M. (Other), Fletcher, J. M. (Other), Kearney, M. T. (Other), Chapman, A. M. (Author), Evaluation of

Seasonal Change in Adrenocorticotropin Concentrations in Response to Thyrotropin-Releasing Hormone in Aged Ponies. Phi Zeta

Research Day. Louisiana State University SVM. Baton Rouge, Louisiana. (September 2015).

Malik, C. (Presenter), Keowan, M. (Other), Fletcher, J. M. (Other), Kearney, M. T. (Other), Chapman, A. M. (Author), Evaluation of

Seasonal Change in Adrenocorticotropin Concentrations in Response to Thyrotropin-Releasing Hormone in Aged Ponies. Merial/NIH

Veterinary Summer Scholars Conference. Merial/NIH Veterinary Summer Scholars Program. Davis, California. (August 2015).

McConnico, R. S. (Author), Walker, N. (Author & Presenter), Large Animal Disaster Bootcamp: Building Community Resilience to

Disasters. Katrina & Rita Symposium: A Decade of Research & Response. Louisiana State University Office of Research and Economic

Development. Baton Rouge, Louisiana. (August 2015).

40


McConnico, R. S., Roy, A. F., Andrews, F. M., 10th International Equine Infectious Diseases Conference (IEIDC X), “Elimination of

the Use of Rubber Stall Mats for Effective Intervention of Nosocomial Salmonella Enterica spp. Infection in a Veterinary Teaching

Hospital,” Buenos Aires, Argentina. (April 10, 2016).

McNulty, M. A. (Author & Presenter), Gillett, A. (Other), Goupil, B. (Other), Mitchell, C. F. (Other), Orthopaedic Research Society, “Effects

of Tiludronate on Bone Growth and Remodelling in Young Horses,” Orlando, Florida. (March 5, 2016).

Mirza, M. H. (Author), Bommala, P. (Author), Richbourg, H. (Author), Rademacher, N. (Author), Kearney, M. T. (Author), Lopez, M. J.

(Author & Presenter), American College of Veterinary Surgery Summit, “Gait Changes Vary Among Horses with Naturally Occurring

Osteoarthritis Following Intra-Articular Administration of Autlogous Platelet-Rich Plasma,” Seattle, Washington. (October 5, 2016).

Newcomer, B. W. (Author & Presenter), Armstrong, C. L. (Author), Riddell, K. P. (Author), Edmondson, M. A. (Author), Walz, P. H.

(Author), Evaluation of Delayed Insemination with Sexed Semen for Non-responding Beef Heifers after Estrus Synchronization. 9th

Annual Conference of the American Association of Bovine Practitioners. American Association of Bovine Practitioners. New Orleans,

Louisiana. (September 2015).

Rabalais, R. (Author & Presenter), Rademacher, N. (Author), Riggs, L. M. (Author), Sonographic Evaluation of the Equine Lateral Plantar

Nerve and its Deep Branch. Louisiana State University SVM Phi Zeta Research Day. Merck Merial Summer Student Research. Baton

Rouge, Louisiana. (September 2015).

Richbourg, H. (Author & Presenter), Mirza, M. H. (Author), Fargason, C. (Author), Rademacher, N. (Author), Kearney, M. T. (Author),

Lopez, M. J. (Author), Intra-Articular Platelet Therapy to Alleviate Pain Associated with Equine Osteoarthritis. Louisiana State

University SVM Phi Zeta Research Day. Baton Roue, Louisiana. (September 2015).

Richbourg, H. (Author & Presenter), Mitchell, C. F., Gillett, A., McNulty, M. A., Phi Zeta Research Day, “Impact of Bisphosphonates on

Bone Remodeling in Young Horses.” (September 27, 2016).

Sandow, C. (Author & Presenter), Fugler, L. A., Leise, B., Riggs, L., Monroe, T., Belknap, J., Eades, S., Louisiana State University SVM

Phi Zeta Research Day, “Ex Vivo Assessment of Structural Integrity and Preliminary Effects of High Concentrations of Insulin,” Phi

Zeta, Louisiana State University SVM, Baton Rouge, Louisiana. (September 2016).

Yang, Q. (Author & Presenter), Takawira, C. (Author), Duan, W. (Author), Lopez, M. J., LSU SVM Phi Zeta Research Day, “Novel

Investigation of Equine Hoof Stem Cells,” Baton Rouge, Louisiana. (September 28, 2016).

Published Abstracts

Andrews, F. M. (2015). In Andrews, F. M. (Ed.), IgM and IgG Responses in Horses and Pony Foals After West Nile Virus and Eastern

Equine Encephalitis Vaccination. American College of Internal Medicine (ACVIM). Published Electronically ACVIM.org

Andrews, F. M., Cruz-Sanabria, J. (2015). In Andrews, F. M. (Ed.), Validation of a Multivariable Colic Predication Model. American

College of Internal Medicine (ACVIM). Published Electronically ACVIM.org

41


Arana, N., Andrews, F. M. (2015). In Andrews, F. M. (Ed.), The Effect of pH on Large Intestinal Ion Transport and Transepithelial

Resistance in Suspected Insulin Resistance Horses. American College of Internal Medicine (ACVIM). Published Electronically ACVIM.

org

Brown, J. L., Sones, J., Boehm, U., Roberson, M. S. (2016). Loss of ERK1/2 Signaling in Cells Expressing the GnRH Receptor Causes

Prolonged Gestation, Dystocia, and Fetal Death. Role of Growth Factor Signaling in Fertility and Pregnancy (pp. OR09-3-OR09-3).

http://press.endocrine.org/doi/abs/10.1210/endo-meetings.2016.RE.14.OR09-3

Diaz, F. A., Gentry, G. T., Eddie, C., Paccamonti, D. L., Bondioli, K. R. (2015). Pregnancies from Vitrified Equine Blastocysts Previously

Subjected to Low-Temperature Storage (vol. 61, pp. 474). Proceedings Ann Conv Am Assoc Eq Pract.

Gautreaux, S., Koch, C., Kearney, M. T., McConnico, R. S. (2015). Salivary Cortisol Levels in Horses Receiving Acupuncture or

Therapeutic Massage. Proceedings of the Louisiana State University SVM Phi Zeta (Merck, NIH) Research Symposium. Baton Rouge,

Lousiana.

Gautreaux, S., Koch, C., Kearney, M. T., McConnico, R. S. (2015). Salivary Cortisol Levels in Horses Receiving Acupuncture or

Therapeutic Massage. Proceedings of the Louisiana State University SVM Phi Zeta (Merck, NIH) Research Symposium. Davis,

California.

Jarazo, J., Gentry, G., Bondioli, K., Lopez, M. J. (2016). Synthetic mRNA to Dedifferentiate Equine Adult Multipotent Stromal Cells. New

Orleans, LA: Orthopaedic Research Society Annual Meeting Proceedings.

Leise, B., Miller, N., Moorman, V., Bass, L., Pittman, S., Rucker, A., Redden, R. (2016). Assessment of Digital Venograms in Non-

Laminitic Horses. American Association of Equine Practitioners.

Leisinger, C. A., Markle, M. L., Paccamonti, D. L., Cramer, E., Pinto, C. R. (2016). Production of Equine Embryos In Vitro Using

Conventional Intracytoplasmic Sperm Injection and a Complete Human Embryo Culture System (vol. 41, pp. 78). J Eq Vet Sci.

Lopez, M. J., Fargason, C., Kelly, L., Del Piero, F., Dasa, V., King, A. (2015). Demineralized Human Bone Matrix with Syngeneic Adult

Adipose-Derived Multipotent Stromal Cells Accelerates Spinal Fusion. International Federation for Adipose Therapeutics and

Science Proceedings.

Lopez, M. J., Jarazo, J., Fargason, C., Bondioli, K., Gentry, G. (2015). Synthetic mRNA to Dedifferentiate Equine Adult Multipotent

Stromal Cells. International Federation for Adipose Therapeutics and Science Proceedings.

Lopez, M. J., Fargason, C., Kelly, L., Del Piero, F., Dasa, V., King, A. (2015). Demineralized Human Bone Matrix with Syngeneic Adult

Adipose-Derived Multipotent Stromal Cells Accelerates Spinal Fusion. American College of Veterinary Surgery Summit Proceedings.

Lopez, M. J., Jarazo, J., Fargason, C., Bondioli, K. (2015). Synthetic mRNA to Dedifferentiate Equine Adult Multipotent Stromal Cells.

North American Veterinary Regenerative Medicine Conference.

42


Lopez, M. J., Duan, W., Haque, M., Kearney, M. T., Gimble, J. (2016). Collagen and Hydroxyapatite Scaffolds Stimulate Distinct

Osteogenesis Pathways. Proceedings, International Federation for Adipose Therapeutics and Science.

Mathias, A. J., Williams, C. C., Welborn, M. G., Navarre, C. B., Coetzee, J. F., Orellana, R. M., Blair, S. J. (2016). Effect of Timing of Local

Anesthesia on Physiological Responses in Calves after Dehorning (vol. 94, pp. 36). Journal of Animal Science.

McConnico, R. S., Stout, R. W., Andrews, F. M., Roy, A. F. (2016). Elimination of the Use of Rubber Stall Mats for Effective Intervention

of Nosocomial Salmonella Enterica spp. Infection in a Veterinary Teaching Hospital. 10th International Equine Infectious Diseases

Conference. Lexington, Kentucky: Equine Journal of Veterinary Science. Published Electronically www.sciencedirect.com/science/

article/pii/S0737080616000423

Mirza, M. H., Bommala, P., Richbourg, H., Rademacher, N., Kearney, M. T., Lopez, M. J. (2016). Gait Changes Vary Among Horses with

Naturally Occurring Osteoarthritis Following Intra-Articular administration of autlogous platelet-rich plasma. Proceedings, American

College of Veterinary Surgery Summit.

Rashmir, A., McConnico, R. S. (2016). The use of serine protease inhibitors in the treatment of equine pemphigus foliaceus.

Proceedings of the 8th World Congress on Veterinary Dermatology. Bordeaux, France: Proceedings of the 8th World Congress on

Veterinary Dermatology.

Sones, J., Woods, A. K., Cha, J., Dey, S. K., Davisson, R. L. (2016). Artificial Synchronization of Ovarian Hormones in Early Pregnancy

Improves Adverse Pregnancy Outcomes Associated with Preeclampsia in the BPH/5 Mouse Model (1 Supplement ed., vol. 30, pp.

1247.4-1247.4). The FASEB Journal.

Xia, J., Baxter, S., Grenier, J., Davisson, R. L., Sones, J. (2016). MicroRNAs Target Decidual Angiogenic Factors During Early Pregnancy

in BPH/5, a Spontaneous Mouse Model of Preeclampsia (1 Supplement ed., vol. 30, pp. 1028.14-1028.14). The FASEB Journal.

43

GRANTS

Funded Proposals

Andrews, Frank M (PI), “Safety of a Fly Spray in Horses,” Sponsored by SmartPak – Private. $21,875. (September 15, 2015 - June 30,

2016).

Andrews, Frank M (PI), Camacho, Pilar, Vineyard, Kelly, Gordon, Mary Beth, Cartmill, Josh, Keowen, Michael L, Garza, Jr., Frank, “Pilot

Study: Effects of Calcified Seaweed (Calmin) on Gastric Juice pH in Horses,” Sponsored by Purina Animal Nutrition, Private, $11,220.

(May 1, 2015 - December 31, 2015).

Andrews, Frank M (PI), Camacho, Pilar, Cartmill, Josh, Keowen, Michael L, Garza, Jr., Frank, “Pilot Study: Effects of Alfa-Lox-Forage on

Equine Gastric Ulcers Scores and Gastric Juice pH in Horses,” Sponsored by Triple Crown Feeds – Private. $61,000. (March 1, 2015 -

December 31, 2015).

Andrews, Frank M (PI), Camacho, Pilar, Cartmill, Josh, Keowen, Michael L, Garza, Jr., Frank, “Pilot Study: Effects of Hydrolyzed

Collagen on Equine Gastric Ulcers Scores and Gastric Juice pH in Horses,” Sponsored by Sonac and Darling Ingredients - Private.

$45,000. (February 13, 2015 - December 31, 2015).

Andrews, Frank M (PI), “Pivotal Study: A 2-Period Crossover Bioequivalence Study Comparing Gastrogard Paste Formulation of

Omeprazole (NADA 141-123) Versus a Generic Omeprazole Formulation when Administered Orally in Horses,” Sponsored by Randlab

Pty, Ltd., 7/85 Alfred Road, Chipping Norton, NSW, Australia 2170, Private, $159,703. (September 30, 2016 - June 30, 2017).

Andrews, Frank M (PI), “Gastroscopy Instructional Video,” Sponsored by Randlab Pty, Ltd., 7/85 Alfred Road, Chipping Norton, NSW,

Australia 2170, Private, $10,300. (December 1, 2016 - February 28, 2017).

Andrews, Frank M (PI), Chapman, Ann M, “A Dose-Ranging Pilot Clinical Trial to Assess the Effectiveness and Field Safety of

Esomeprazole for the Treatment of Equine Gastric Ulcer Syndrome (EGUS),” Sponsored by Kindred BioScience, Private, $221,490.

(April 28, 2016 - Present).

Andrews, Frank M (PI), Chapman, Ann M, “Efficacy & Safety Field Study of Ciclesonide for Horses with Recurrent Airway Obstruction

(RAO) and/or Summer Pasture Associated Obstructive Pulmonary Disease (SPAOPD),” Sponsored by Boehringer Ingelheim

Vetmedica, Private, $50,000. (September 28, 2016 - December 31, 2017).

Andrews, Frank M (PI), Riggs, Laura M, Lopez, Mandi J, “Effect of an Oral Supplement Containing Curcumin Extract (Longvida) on

Lameness due to Osteoarthritis or Degenerative Disease and Gastric Ulcer Scores,” Sponsored by W. F. Young Company, Private,

$161,131. (June 1, 2016 - July 1, 2017).

Burgess, Brandy (PI), Morley, Paul, McConnico, Rebecca S, Pabilonia, Kristy, “Evaluation of a Rapid Test Strip, PCR, and Aerobic

Culture for Detection of Salmonella in Equine Fecal Samples in the Clinical Setting,” Sponsored by Boehringer Ingelheim Vetmedica,

Inc., Private, $25,000. (2016).

Carter, Renee T (PI), Camacho-Luna, Pilar, Andrews, Frank M, Gaschen, Lorrie, “Effect of Topical 1% Atropine Sulfate Ophthalmic

Solution on the GI Motility and Transit Time in the Horse,” Sponsored by Charles V. Cusimano Equine Health Studies Program,

Louisiana State University, $12,000. (August 2016 -Present).

44

GRANTS

Cary, Julie (PI), Compton, Nashua, Lutter, Dylan, Godfrey, Jennifer, Fulcher, Jake, Mitchell, Colin F, “An evaluation of different surgical

training techniques for veterinary students performing subcutaneous mass removal,” Sponsored by Departmental Research, Other.

(September 2015 - Present).

Chapman, Ann M (PI), “Evaluation of α-melanocyte-stimulating hormone and proopiomelanocortin responses to thyrotropin releasing

hormone in young and aged ponies,” Sponsored by EHSP Corp Fund, Louisiana State University, $12,000. (September 4, 2015

- Present).

Davolli, Gabriel A (PI), Pinto, Carlos R, Paccamonti, Dale L., “A. Title: Antiluteogenic Treatment of Hemorrhagic Anovulatory Follicles,”

Sponsored by Charles V. Cusimano EHSP grant, Louisiana State University, $6,000. (August 15, 2016 - June 30, 2017).

Eades, Susan C, Belknap, Jim (PI), “Laminar growth factor signaling in equine metabolic syndrome-associated laminitis: establishment

of therapeutic targets,” Sponsored by American Quarter Horse Association, Private, $68,225. (July 2015 - Present).

Eades, Susan C (PI), Fugler, Lee Ann, “Effects of Pentoxifylline on Cytokine Production in Carbohydrate Overload Laminitis,”

Sponsored by Departmental Research, Louisiana State University, $5,000. (May 2015 - Present).

Eades, Susan C (PI), Riggs, Laura M, Fugler, Lee Ann, Sandow, Cole, “Ex vivo equine digital laminar explant integrity and

phosphorylation events in response to high concentrations of insulin,” Sponsored by EHSP Grants Program, State, $12,000.

(September 1, 2015 - Present).

Gauthier, Ted (PI), Paccamonti, Dale L., Pinto, Carlos R, “The Use of Membrane Disrupting Peptide/Peptoid LHRH Conjugates to

Control Wild Horse and Burro Populations,” Sponsored by US Department of Interior, Bureau of Land Management, Wild Horse and

Burro Program, Federal, $850,002. (October 2015 - Present).

Geautraux, Sarah (PI), Koch, Catherine, Bruns, Susan, McConnico, Rebecca S, “Acupuncture Treatment and the Attenuation of

Salivary Cortisol Levels in the Domestic Horse,” Sponsored by Merial/NIH Veterinary Summer Scholars Program Summer Biomedical

Research Opportunities for Veterinary Students, Louisiana State University, $5,500. (May 15, 2015 - August 15, 2015).

Leise, Britta S (PI), “Assessment of Keratinocyte Wound Healing and Growth Factor Production In Vitro After Exposure to Bone

Marrow Derived Mesenchymal Stem Cells or Lipopolysaccharide,” Sponsored by Charles V. Cusimano EHSP Research Grant,

Louisiana State University, $11,617. (June 2016 - Present).

Leisinger, Chelsey A (PI), Pinto, Carlos R, Sones, Jennifer, Paccamonti, Dale L., “Characterization of Steroid Hormone Responsive

Genes in the Equine Endometrium During Induced Aluteal Cycles,” Sponsored by VCS CORP, Louisiana State University, $4,000.

(August 15, 2016 - June 30, 2017).

Leisinger, Chelsey A (PI), Pinto, Carlos R, Sones, Jennifer, Paccamonti, Dale L., “Developmental Characteristics of In Vivo Equine

Embryos Produced During Induced Aluteal Cycles,” Sponsored by Charles V. Cusimano EHSP grant, Louisiana State University,

$6,000. (August 15, 2016 - June 30, 2017).

Lopez, Mandi J (PI), “EpiBone Graft Dosing Study-Supplement,” Sponsored by EpiBone, Private, $53,281. (October 1, 2015 - Present).

45

GRANTS

Lopez, Mandi J (PI), “GrabTen - Innovative soft tissue tensioning and fixation device,” Sponsored by LSU Board of Supervisors LIFT2,

State, $36,783. (March 1, 2015 - Present).

Lopez, Mandi J (PI), Duan, Wei, “Selecting adipose-derived stromal cells for osteogenesis with fluorescence-activated cell sorting,”

Sponsored by LSU School of Veterinary Medicine Equine Health Studies Program, Local, $12,000. (September 1, 2015 - Present).

Lopez, Mandi J (PI), “PAH-100 to Improve Hind Limb Use in Dogs with Coxofemoral Joint Disease,” Sponsored by Piedmont Animal

Health, Private, $126,420. (August 15, 2016 - August 14, 2017).

Lopez, Mandi J (PI), Duan, Wei, “Identification of a Synergistic Cell Immunophenotype to Augment De Novo Bone Generation by

Equine Adipose Derived Multipotent Stromal Cells,” Sponsored by Louisiana State University Equine Health Studies Program, Local,

$8,000. (September 2016 - June 2017).

Lopez, Mandi J, Koh, Ronald, “Agmatine Supplementation for Painful Thoracolumbar Intervertebral Disc Disease in Dogs,” Sponsored

by American Holistic Veterinary Medical Foundation, Private, $29,850. (May 9, 2016 - May 8, 2017).

Lopez, Mandi J (PI), Kraus, Peter, “A Revolutionary Mechanism to Support CuttingEdge Discoveries to Prevent and Treat Degenerative

Hip Disease,” Sponsored by LSU-Health Sciences Center, State, $8,000. (July 1, 2016 - June 30, 2017).

Lopez, Mandi J (PI), Yang, Qingqiu, “Characterization of Adult Equine Stem Cells From Normal and Laminitic Hooves,” Sponsored by

USDA, Federal, $7,500. (October 1, 2016 - September 30, 2017).

Lopez, Mandi J (PI), Yang, Qingqiu, Takawira, Catherine, “Isolation and Characterization of Adult Equine Stem Cells from Normal and

Laminitic Hooves,” Sponsored by LSU Equine Health Studies Program, Local, $6,000. (September 2016 - July 2017).

Markle, Mariah (PI), Pinto, Carlos R, “Effects of Systemic Serial Administration of Prostaglandin F2 Alpha (PGF2α) on the Early

Developing Corpus Luteum of Mares,” Sponsored by Charles V. Cusimano EHSP grant, Louisiana State University, $6,000. (August

15, 2016 - June 30, 2017)

McConnico, Rebecca S (PI), Mirza, Mustajab H, “Northwestern State University Disaster Response Training for Technician Students,”

Sponsored by Louisiana State Animal Response Team (Walter J. Ernst Jr. Foundation of the LVMA), State, $4,000. (March 1, 2015 -

June 1, 2015).

McConnico, Rebecca S (PI), Mirza, Mustajab H, “Support for CE/Professional Course in Large Animal Handling and Technical Large

Animal Emergency Rescue,” Sponsored by American Association of Equine Practitioners, Private, $3,000. (September 2016 - June

30, 2017).

McConnico, Rebecca S (PI), Mirza, Mustajab H, Duhon, Brandy, Wolfson, Wendy, “Medical Support for Equine Flood Victims in

Louisiana,” Sponsored by May HTR Foundation, Private, $14,480. (September 2, 2016 - September 1, 2017).

McConnico, Rebecca S (PI), Poirrier, Renee, Littlefield, Martha, Wolfson, Wendy, Mirza, Mustajab H, “Support to Purchase Equipment

for Animal Response - Great Flood of 2016,” Sponsored by ASPCA, Private, $10,000. (September 1, 2016 - August 31, 2017).

46

GRANTS

Mitchell, Colin F (PI), McNulty, Margaret A, “Influence of clodronate on bone density and bone formation in young horses,” Sponsored

by Equine Health Studies Program, Louisiana State University, $12,000. (August 1, 2015 - Present).

Pinto, Carlos R (PI), “Effect of GnRH administration on in vitro maturation of equine oocytes,” Sponsored by Charles V. Cusimano

EHSP grant, Louisiana State University, $11,635. (August 15, 2015 - June 30, 2016).

Pinto, Carlos R, Leisinger, Chelsey (PI), Paccamonti, Dale L., “Fertility of stallion semen cryopreserved in cryovials and subjected to

repeat partial thaw refreeze cycles in an ICSI program,” Sponsored by Charles Cusimano EHSP grant, Louisiana State University,

$5,889. (August 15, 2015 - June 30, 2016).

Rabalais, Reid (PI), Rademacher, Nathalie (PI), Riggs, Laura M (PI), “Dynamic Sonographic Evaluation of the Equine Hind Suspensory

Ligament, lateral Plantar Nerve and Deep Branch of the Lateral Plantar Nerve,” Sponsored by Merck Merial Summer Student

Research, Private, $5,619. (May 18, 2015 - July 31, 2015).

Richbourg, Heather, Lopez, Mandi J (PI), Schachner, Emma, “Shoe shape affects motion of the distal phalanx in normal and laminitic

hooves,” Sponsored by LSU School of Veterinary Medicine Equine Health Studies Program, $6,000. (September 1, 2015 - Present).

Riggs, Laura M, Grimes, Janet A, Hodgson, Michelle, “Effect of Multiple Sterilizations on Biomechanical Properties of Surgical

Screws,” Sponsored by VCS Corp grant, Louisiana State University. $3,217. (October 2015 - Present).

Sones, Jennifer, Beavers, Kelli (PI), “Measurement of Serum Amyloid A Levels in Clinical Cases of Equine Placentitis.,” Sponsored by

Equine Health Studies Program, LSU SVM, Louisiana State University, $6,000. (August 24, 2016 - Present).

Sones, Jennifer, Leisinger, Chelsey (PI), “Characterization of Steroid Hormone Responsive Genes in the Equine Endometrium During

Induced Aluteal Cycles,” Sponsored by Veterinary Clinical Sciences, LSU SVM, Louisiana State University, $4,000. (October 10, 2016

- Present).

Sones, Jennifer, Leisinger, Chelsey (PI), “Developmental Characteristics of In Vivo Equine Embryos Produced During Induced Aluteal

Cycles,” Sponsored by Equine Health Studies Program, LSU SVM, Louisiana State University, $6,000. (August 24, 2016 - Present).

Sones, Jennifer L (PI), Redman, Leanne M, “The Role of Maternal Adipose Tissue in the Preeclamptic-Like BPH/5 Mouse,” Sponsored

by Louisiana Biomedical Collaborative Research Program, Louisiana State University, $50,000. (September 22, 2016 - Present).

Witonsky, Sharon (PI), Andrews, Frank M, Del Piero, Fabio, Keowen, Michael L, Garza, Jr., Frank, “Equine Protozoal Myeloencephalitis

(EPM): Identifying the immune response and the role of infection,” Sponsored by Virginia Horse Industry Board, State, $10,000. (July

1, 2015 - July 1, 2016).


(EPM): Identifying the immune response and the role of infection,” Sponsored by Virginia Maryland Regional College of Veterinary

Medicine Internal Grant, Other, $19,998. (July 1, 2015 - July 1, 2016).

47

GRANTS

Woodward, Michelle (PI), Pucheu-Haston, Cherie M, “Determination of Allergen Irritant Threshold Concentrations for Equine

Intradermal Testing in Normal Horses in the Southeastern United States,” Sponsored by Equine Health Studies Program, Louisiana

State University, $8,558. (August 3, 2016 - Present).

Pending Proposals

Beehan, David (PI), Lyle, Sara K, “Equine Endometritis and Biofilm-Forming Escherichia Coli,” Sponsored by American Quarter Horse

Foundation. Private. (April 2015 - March 2016).

Beehan, David (PI), Lyle, Sara K, “Equine Endometritis and Biofilm-forming Escherichia coli,” Sponsored by American Quarter Horse

Association, Private. (December 2014 - Present).

Beehan, David (PI), Lyle, Sara K, “Equine Endometritis and Biofilm-Forming Escherichia Coli.,” Sponsored by American Quarter Horse

Foundation, Private. (April 2015 - March 2016).

Devireddy, Ram (PI), Hayes, Daniel, Lopez, Mandi J, “Magnetogenetic Directed Deep Tissue Differentiation of Stem Cells for Neuronal

Repair,” Sponsored by National Institutes of Health. Federal. $1,000,000. (2015).

Lopez, Mandi J (PI), Schachner, Emma, Richbourg, Heather, “3-D Models of Bone Motion in Normal and Laminitic Hooves,” Sponsored

by Grayson Jockey Club Research Foundation. Private. $48,267. (2015).

Macpherson, Margo, Giguere, S, Pozor, M, Lyle, Sara K, “Firocoxib Properties in Equine Pregnancy and Placentitis,” Sponsored by

Grayson Jockey Club Research Foundation. Private. (2014 - Present).

McConnico, Rebecca S (PI), Wolfson, Wendy, Duhon, Brandy, “Service Outreach for Parish Large Animal Welfare,” Sponsored by

American Society for the Prevention of Cruelty to Animals. Private, $4,000. (December 2015 - Present).

Riggs, Laura (PI), Sandow, Cole, “Evaluation of the Short-Term Effects of IntraArticular Administration of Platelet Rich Plasma in Horses

with Experimentally Induced Synovitis,” Sponsored by American College of Veterinary Surgeons, Private. (June 2016 - Present).

Active Grants in 2015

Baia, Petrisor (PI), Riggs, Laura M, Riggs, Laura M, “Histomorphometric and Surface Topography Analysis of Stainless Steel Implants

with Different Surface Treatment,” Sponsored by Charles V. Cusimano EHSP. Louisiana State University. $8,000. (August 2012

- Present).

Beehan, David (PI), Lyle, Sara K, “Detection of Uropathogenic Virulence Genes in Equine Reproductive Tract Escherichia Coli by

Polymerase Chain Reaction and Comparing Results with Isolate Biofilm Forming Potential,” Sponsored by Department of Veterinary

Clinical Science. Louisiana State University. $1,710. (October 2014 - Present).

Beehan, David (PI), Lyle, Sara K, Krekler, Nathalie, Doerrler, W., Paccamonti, Dale L., “The Establishment of Minimal Inhibitory

Concentrations for Biofilm-Forming Escherichia Coli Isolates for Both Antimicrobial and Nonantimicrobial Therapeutic Agents,”

Sponsored by Charles V. Cusimano Equine Health Studies Program. Louisiana State University. $9,176. (August 2014 - Present).

48

GRANTS

Burba, Daniel J, Andrews, Frank M, “Prevalence of Gastric Ulcers in Horses that Crib Bite - Clinical Study,” Sponsored by EHSP.

Louisiana State University. $5,000. (October 2012 - Present).



Inc. Private. $25,000. (December 2014 - March 2016).

Chapman, Ann M (PI), “Seasonal Release of Adrenocorticotrophic Hormone Concentrations in Response to Thyrotropin Releasing

Hormone in Normal Ponies in Louisiana.” Sponsored by EHSP Corp Fund. Louisiana State University. $10,000. (August 9, 2013 - June

30, 2015).

DiGiovanni, Daria (PI), McCauley, Charles T, Riggs, Laura M, Mitchell, Colin F, Burba, Daniel J, Mirza, Mustajab H, Del Piero, Fabio,

“Histologic Changes to the Muscular Portion of the Hind Suspensory Ligament of Horses as a Result of Neurectomy of the Deep

Branch of the Lateral Plantar Nerve.,” Sponsored by Charles V. Cusimano EHSP, Louisiana State University, $1,340. (October 2014

- Present).

Duan, Wei, Lopez, Mandi J (PI), “Loading Adult Equine Multipotent Stromal Cells Onto Customized Scaffold by Perfusion Bioreactor

System for Cell Osteogenesis,” Sponsored by LSU School of Veterinary Medicine Equine Health Studies Program. Local. $6,000.

(July 1, 2014 - June 30, 2015).

Lopez, Mandi J (PI), “EpiBone Graft Dosing Study,” Sponsored by EpiBone. Private. $180,943. (October 1, 2014 - Present).

Lopez, Mandi J, Bates, Karl (PI), “An Open Source Equine Computer Model for Locomotor and Veterinary Research,” Sponsored by

Royal Society International Exchanges. Other. $15,000. (March 2014 - Present).

Lopez, Mandi J, Vunjak-Novakovic, G (PI), “Craniofacial Tissue Engineering,” Sponsored by National Institutes of Health. Federal.

$324,736. (September 20, 2013 - Present).

Lopez, Mandi J (PI), Richbourg, Heather, Schachner, Emma, “Forces of Horses: A Quantitative and 3-Dimensional Equine Model,”

Sponsored by Louisiana Board of Regents Pilot Funding for New Research (PFUND). Federal. $10,000. (October 1, 2014 - September

30, 2015).

Lopez, Mandi J (PI), Richbourg, Heather, Schachner, Emma, “Forces of Horses: A Computer Model to Pair Horses with Patients for

Therapeutic Riding,” Sponsored by Equine Health Studies Program. Local. $12,000. (October 1, 2014 - June 30, 2015).

Lopez, Mandi J (PI), Ryan, William, “A Novel In Vitro Model of Equine Hoof Stem Cells for Laminitis Research,” Sponsored by Merial -

Summer Scholars Program. $5,000. (May 2014 - May 2015).

Lyle, Sara K (PI), Mitchell, Colin F, Riggs, Laura M, McCauley, Charles T, “Serum Testosterone Concentrations Following Human

Chorionic Gonadotropin (hCG) Stimulation in Cryptorchid Horses Before and After Castration,” Sponsored by Charles V. Cusimano

EHSP Grant. $2,745. (October 2014 - Present).

49

GRANTS

McCauley, Charles T, DiGiovanni, Daria, Riggs, Laura, Mitchell, Colin, Burba, Dan, Mirza, Mustajab, Del Piero, Fabio, “Histologic

Changes to the Muscular Portion of the Hind Suspensory Ligament of Horses as a Result of Neurectomy of the Deep Branch of

the Lateral Plantar Nerve,” Sponsored by Charles V. Cusimano EHSP Grant. Louisiana State University. $1,340. (September 15, 2014

- Present).

McCauley, Charles T (PI), DiGiovanni, Daria, Gaschen, Lorrie, Riggs, Laura M, Mitchell, Colin F, Burba, Daniel J, Mirza, Mustajab H,

“The Effect of Neurectomy of the Deep Branch of the Lateral Plantar Nerve on the Biomechanical Properties and Diagnostic Imaging

Characteristics of the Equine Hind Suspensory Ligament,” Sponsored by Charles V. Cusimano EHSP, Louisiana State University.

$11,998. (October 2014 - Present).

McConnico, Rebecca S (PI), “SVM-LSART Support Fund (Disaster Training & Response),” Sponsored by Noah’s Wish. Louisiana State

University. $4,750. (July 2014 - December 2015).

Mitchell, Colin F (PI), McNulty, Margaret A, “Influence of Tiludronate on Bone Density and Bone Formation in Young Horses,”

Sponsored by Equine Health Studies Program. Louisiana State University. $9,500. (September 1, 2014 - July 1, 2015).

Pinto, Carlos R, Paccamonti, Dale L., Leisinger, Chelsey A (PI), “The Effect of Repeated Freeze-Thaw Cycles on Semen Parameters in

the Stallion,” Sponsored by VCS Corp funds. Louisiana State University. $3,167. (October 1, 2014 - Present).

Pinto, Carlos R, Paccamonti, Dale L. (PI), “Equine Assisted Reproduction Program,” Sponsored by Equine Veterinary Management of

Louisiana. Private. $96,722. (November 1, 2014 - November 1, 2019).

Richbourg, Heather, Lopez, Mandi J (PI), “Shoe Shape Affects Motion of the Distal Phalanx (P3) in Normal and Laminitic Equine

Hooves: Three Dimensional Models of P3 Motion Within the Hoof,” Sponsored by Veterinary Clinical Sciences Corp. Local. $2,000.

(September 2014 - June 30, 2015).

Riggs, Laura M, Hansen, Nicole M., “Are Implanted Prosthetic Legs for Horses Possible,” Sponsored by Experiment.com crowd

funding. Private, $10,000. (November 15, 2014 - Present).

Seibert, Lyndsea, Welborn, Matthew G, Kelly, Vicky, Young, Kristen, Garza, Javier, Miller, James E (PI), “Evaluation of Eprinomectin

(LongRange) for Long-Term Control of Gastrointestinal Nematode Infection in Nursing Calves During Summer Grazing,” Sponsored by

Merial Veterinary Services. Private. (June 2, 2014 - May 30, 2015).

Williams, Cathleen (PI), Mathias, Amanda, Welborn, Matthew G, Navarre, Christine B, “Effects of Timing and Administration of

Anesthesia and Analgesia on Pain Management During Dehorning of Dairy Calves,” Sponsored by Departmental Research. Louisiana

State University Dept. of Animal Science. $2,000. (December 11, 2014 - January 14, 2015).

Active Grants in 2016

Andrews, Frank M (PI), “Safety of a Fly Spray in Horses,” Sponsored by SmartPak, Private, $21,875. (September 15, 2015 - June 30,

2016).

50

GRANTS

Baia, Petrisor (PI), Riggs, Laura M, Riggs, Laura M, “Histomorphometric and Surface Topography Analysis of Stainless Steel Implants

with Different Surface Treatment,” Sponsored by Charles V. Cusimano EHSP, Louisiana State University, $8,000. (August 2012

- Present).

Beehan, David (PI), Lyle, Sara K, “Detection of Uropathogenic Virulence Genes in Equine Reproductive Tract Escherichia Coli by

Polymerase Chain Reaction and Comparing Results with Isolate Biofilm Forming Potential,” Sponsored by Department of Veterinary

Clinical Science, Louisiana State University, $1,710. (October 2014 - Present).

Beehan, David (PI), Lyle, Sara K, Krekler, Nathalie, Doerrler, W., Paccamonti, Dale L., “The Establishment of Minimal Inhibitory

Concentrations for BiofilmForming Escherichia Coli Isolates for Both Antimicrobial and Non- Antimicrobial Therapeutic Agents,”

Sponsored by Charles V. Cusimano Equine Health Studies Program, Louisiana State University, $9,176. (August 2014 - July 2016).



Inc., Private, $25,000. (December 2014 - March 2016).

Chapman, Ann M (PI), “Evaluation of α-Melanocyte-Stimulating Hormone and Proopiomelanocortin Responses to Thyrotropin

Releasing Hormone in Young and Aged Ponies,” Sponsored by EHSP Corp Fund, Louisiana State University, $12,000. (September 4,

2015 - Present).

DiGiovanni, Daria (PI), McCauley, Charles T, Riggs, Laura M, Mitchell, Colin F, Burba, Daniel J, Mirza, Mustajab H, Del Piero, Fabio,

“Histologic Changes to the Muscular Portion of the Hind Suspensory Ligament of Horses as a Result of Neurectomy of the Deep

Branch of the Lateral Plantar Nerve.,” Sponsored by Charles V. Cusimano EHSP, Louisiana State University, $1,340. (October 2014

-Present).

Eades, Susan C, Belknap, Jim (PI), “Laminar Growth Factor Signaling in Equine Metabolic Syndrome-Associated Laminitis:

Establishment of Therapeutic Targets,” Sponsored by American Quarter Horse Association, Private, $68,225. (July 2015 - Present).

Eades, Susan C (PI), Fugler, Lee Ann, “Effects of Pentoxifylline on Cytokine Production in Carbohydrate Overload Laminitis,”

Sponsored by Departmental Research, Louisiana State University, $5,000. (May 2015 - Present).

Eades, Susan C (PI), Riggs, Laura M, Fugler, Lee Ann, Sandow, Cole, “Ex Vivo Equine Digital Laminar Explant Integrity and

Phosphorylation Events in Response to High Concentrations of Insulin,” Sponsored by EHSP Grants Program, State, $12,000.

(September 1, 2015 - Present).

Gauthier, Ted (PI), Paccamonti, Dale L., Pinto, Carlos R, “The Use of Membrane Disrupting Peptide/Peptoid LHRH Conjugates to

Control Wild Horse and Burro Populations,” Sponsored by US Department of Interior, Bureau of Land Management, Wild Horse and

Burro Program, Federal, $850,002. (October 2015 -Present).

Lopez, Mandi J (PI), “GrabTen - Innovative Soft Tissue Tensioning and Fixation Device,” Sponsored by LSU Board of Supervisors

LIFT2, State, $36,783. (March 1, 2015 - Present).

51

GRANTS

Lopez, Mandi J, Bates, Karl (PI), “An Open Source Equine Computer Model for Locomotor and Veterinary Research,” Sponsored by

Royal Society International Exchanges, Other, $15,000. (March 2014 - February 2016).

Lopez, Mandi J (PI), De Caro Carella, Chiara, “EpiBone Graft Dosing Study,” Sponsored by EpiBone, Private, $180,943. (October 1,

2014 - Present).

Lopez, Mandi J (PI), De Caro Carella, Chiara, “EpiBone Graft Dosing StudySupplement,” Sponsored by EpiBone, Private, $53,281.

(October 1, 2015 - Present).

Lopez, Mandi J (PI), Duan, Wei, “Selecting Adipose-Derived Stromal Cells for Osteogenesis with Fluorescence-Activated Cell Sorting,”

Sponsored by Louisiana State University SVM Equine Health Studies Program, Local, $12,000. (September 1, 2015 - June 30, 2016).

Lopez, Mandi J, Vunjak-Novakovic, G (PI), De Caro Carella, Chiara, “Craniofacial Tissue Engineering,” Sponsored by National

Institutes of Health, Federal, $324,736. (September 20, 2013 - Present).

Lyle, Sara K (PI), Mitchell, Colin F, Riggs, Laura M, McCauley, Charles T, “Serum Testosterone Concentrations Following Human

Chorionic Gonadotropin (hCG) Stimulation in Cryptorchid Horses Before and After Castration,” Sponsored by Charles V. Cusimano

EHSP Grant, $2,745. (October 2014 - Present).

McCauley, Charles T, Di Giovanni, Daria, Riggs, Laura, Mitchell, Colin, Burba, Dan, Mirza, Mustajab, Del Piero, Fabio, “Histologic

Changes to the Muscular Portion of the Hind Suspensory Ligament of Horses as a Result of Neurectomy of the Deep Branch of

the Lateral Plantar Nerve,” Sponsored by Charles V. Cusimano EHSP Grant, Louisiana State University, $1,340. (September 15, 2014

- Present).

McCauley, Charles T (PI), DiGiovanni, Daria, Gaschen, Lorrie, Riggs, Laura M, Mitchell, Colin F, Burba, Daniel J, Mirza, Mustajab H,

“The Effect of Neurectomy of the Deep Branch of the Lateral Plantar Nerve on the Biomechanical Properties and Diagnostic Imaging

Characteristics of the Equine Hind Suspensory Ligament,” Sponsored by Charles V. Cusimano EHSP, Louisiana State University,

$11,998. (October 2014 - Present).

McCauley, Charles T, DiGiovanni, Daria, Riggs, laura, Mitchell, Colin, Burba, Dan, Mirza, Mustajab, Gaschen, Lorrie, “The Effect

of Neurectomy of the Deep Branch of the Lateral Plantar Nerve on the Biomechanical Properties and Diagnostic Imaging

Characteristics of the Equine Hind Suspensory Ligament,” Sponsored by Charles V. Cusimano EHSP Grant, Louisiana State University,

$11,998. (September 15, 2014 - Present).

McConnico, Rebecca S (PI), Wolfson, Wendy, Duhon, Brandy, “Service Outreach for Parish Large Animal Welfare,” Sponsored by

American Society for the Prevention of Cruelty to Animals, Private, $4,000. (December 2015 - October 15, 2016).

Mitchell, Colin F (PI), McNulty, Margaret A, “Influence of Clodronate on Bone Density and Bone Formation in Young Horses,”

Sponsored by Equine Health Studies Program, Louisiana State University, $12,000. (August 1, 2015 - Present).

Pinto, Carlos R (PI), “Effect of GnRH Administration on In Vitro Maturation of Equine Oocytes,” Sponsored by Charles V. Cusimano

EHSP grant, Louisiana State University, $11,635. (August 15, 2015 - June 30, 2016).

52

GRANTS

Pinto, Carlos R, Leisinger, Chelsey (PI), Paccamonti, Dale L., “Fertility of Stallion Semen Cryopreserved in Cryovials and Subjected to

Repeat Partial Thawrefreeze Cycles in an ICSI Program,” Sponsored by Charles Cusimano EHSP grant, Louisiana State University,

$5,889. (August 15, 2015 - June 30, 2016).

Pinto, Carlos R, Paccamonti, Dale L. (PI), “Equine Assisted Reproduction Program,” Sponsored by Equine Veterinary Management of

Louisiana, Private, $96,722. (November 1, 2014 - Present).

Richbourg, Heather, Lopez, Mandi J (PI), Schachner, Emma, “Shoe Shape Affects Motion of the Distal Phalanx in Normal and Laminitic

Hooves,” Sponsored by LSU School of Veterinary Medicine Equine Health Studies Program, $6,000. (September 1, 2015 - June 30,

2016).

Riggs, Laura M, Grimes, Janet A, Hodgson, Michelle, “Effect of Multiple Sterilizations on Biomechanical Properties of Surgical

Screws,” Sponsored by VCS Corp grant, Louisiana State University. (October 2015 - Present).

Riggs, Laura M, Hansen, Nicole M., “Are Implanted Prosthetic Legs for Horses Possible,” Sponsored by Experiment.com crowd

funding, Private, $10,000. (November 15, 2014 - December 2016).


(EPM): Identifying the Immune Response and the Role of Infection,” Sponsored by Virginia Horse Industry Board, State, $10,000. (July

1, 2015 - July 1, 2016).


(EPM): Identifying the Immune Response and the Role of Infection,” Sponsored by Virginia Maryland Regional College of Veterinary

Medicine Internal Grant, Other, $19,998. (July 1, 2015 - July 1, 2016).

53

HONORS AND AWARDS

AWARDS

Armstrong, Chance L.

Lee County Cattlemen’s Association Presidents Award, Lee County Cattlemen’s Association. (January 28, 2015).

Chapman, Ann M.

Dean’s Teacher Merit Honor Roll, Louisiana State University, School of Veterinary Medicine. (May 2015).

Dean’s Teacher Merit Honor Roll, Louisiana State University SVM. (April 29, 2016).

da Cunha, Anderson F.

10 Years Service Award, Louisiana State University. (July 1, 2015).

Dean’s Teacher Merit Honor Role, School of Veterinary Medicine. (May 2, 2015).


De Caro Carella, Chiara

The Honor Society of Phi Kappa Phi Initiation. (February 16, 2016).

Eades, Susan

Dean’s Teacher Merit Honor Roll, Louisiana State University SVM. (May 2015).

Paula and Milton Shepard Professorship. (July 1, 2015).

Fletcher, Jon

Dean’s Teacher Merit Honor Role, LSU School of Veterinary Medicine. (May 2015).

Gaschen, Lorrie

Dean’s Teacher Merit Honor Role (Year I), LSU School of Veterinary Medicine. (December 2015).

Dean’s Teacher Merit Honor Roll Year 3, Louisiana State University SVM. (December 20, 2016).

Granger, L. Abbigail

Dean’s Teacher Merit Honor Role (Year I), LSU School of Veterinary Medicine. (2015).

Dean’s Teacher Merit Honor Role (Year II, LSU School of Veterinary Medicine. (2015).

Phi Kappa Phi non-tenured faculty award, LSU Alumni Association & the LSU chapter of the Honor Society of Phi Kappa Phi.

(March 31, 2016).

Leise, Britta

Deans Teacher Merit Honor Roll, Louisiana State University SVM. (April 2016).

54

HONORS AND AWARDS

Lopez, Mandi J.

Fellows Program Nomination, National Academy of Inventors. (October 2015).

First Place (PhD Student Competition), Phi Zeta Research Emphasis Day Poster Competition, Tau Chapter, Phi Zeta.

(September 30, 2015).

Recognition of Patent Issue, Office of Innovation and Technology Commercialization. (May 19, 2015).

National Academy of Inventors Fellow, National Academy of Inventors. (December 2016).

Recognition of Patent Issue - 9,044,315, Office of Innovation and Technology Commercialization. (May 19, 2016).

McConnico, Rebecca S.

Dean’s Teacher Merit Honor Role, LSU School of Veterinary Medicine. (2015).

Dean’s Teacher Merit Honor Roll, Louisiana State University SVM. (May 15, 2016).

Mitchell, Colin F.


Mirza, Mustajab H.

Dean’s Teacher Merit Honor Role, LSU School of Veterinary Medicine. (2015).

Paccamonti, Dale Lee

Dean’s Teacher Merit Honor Roll, Louisiana State University SVM. (2016).

Pucheu-Haston, Cherie M.

Dean’s Teacher Merit Honor Roll, LSU SVM. (May 1, 2015).

Master of Ceremonies, 2015 SVM Awards and Honors Ceremony. (May 1, 2015).

Rising Faculty Research Award 2015, LSU Alumni Association. (May 5, 2015).

Dean’s Teacher Merit Honor Roll, Louisiana State University SVM.. (April 29, 2016).

Outstanding teacher selected by Class of 2019. (April 29, 2016).

Zoetis Award for Veterinary Research Excellence, Zoetis. (March 16, 2016).

Rademacher, Nathalie

Dean’s Teacher Merit Honor Roll, LSU Year I students. (May 1, 2015).

Summer Research Award, Merck Merial Research Scholar Program. (March 2015).

55

HONORS AND AWARDS

Dean’s Teacher Merit Honor Roll, LSU Year I and II students, Louisiana State University SVM. (April 29, 2016).

Riggs, Laura M.

Dean’s Teacher Merit Honor Roll, LSU SVM. (May 2015).


Welborn, Matthew G.

2015 Dean’s Teacher Merit Honor Role, SVM. (May 1, 2015).

2015 Dean’s Teacher Merit Honor Role, SVM. (May 1, 2015).


Offices Held in Professional Societies

Armstrong, Chance Lee

Lee County Cattlemen’s Board of Directors (January 1, 2014 - January 1, 2017) Alabama Cattlemen’s Association

Paccamonti, Dale Lee

Member, Educational Programs Committee (December 2014 - December 2016), American Association of Equine

Practitioners

Member, ACT representative on ABVS Committee (July 2005 - July 2020) American Veterinary Medical Association

Pinto, Carlos Roberto Fontes

Scientific Abstract Review Committee Member (2015 - 2019) American College of Theriogenologists

Rademacher, Nathalie

President (October 24, 2014 - October 2016) Veterinary Ultrasound Society of the American College of Veterinary Radiology

Credential Committee (August 2014 - November 30, 2016) European College of Veterinary Diagnostic Imaging

Editorial Review Boards

Andrews, Frank Michael

Editor, Journal Editor, Equine Veterinary Education, Lexington, Kentucky. (September 1, 2013 - Present).

56

HONORS AND AWARDS

Gaschen, Lorrie

Editor, Associate Editor, Veterinary Radiology & Ultrasound. (2007 - Present).

Lopez, Mandi J.

Editor, Associate Editor, Veterinary Surgery. (2015).

Editor, Associate Editor, Veterinary Surgery. (2016).

Pinto, Carlos Roberto Fontes

Editor, Associate Editor, Journal of Small Animal Practice, Oxford. (July 1, 2008 - Present).

Editorial Review Board Member, Journal of Small Animal Practice, Oxford. (July 1, 2008 - Present).

Pucheu-Haston, Cherie M.

Editorial Review Board Member, Veterinary Dermatology Journal Editorial Review Board. (December 2, 2014 - Present).

Riggs, Laura M.

Editorial Review Board Member, Frontiers in Veterinary Science: Veterinary Surgery and Anesthesia. (March 2016 - Present).

57

FACILITIES AND EQUIPMENT

State-of-the-Art Facilities and Equipment

The Equine Health Studies Program is an interdepartmental, multidisciplinary equine biomedical program within the LSU School of

Veterinary Medicine that is dedicated to the health, well-being and performance of horses through veterinary research, education,

and service. A diverse group of faculty, graduate students, post-doctoral fellows and staff conduct cutting-edge research in equine

health and disease. The program maintains a herd of approximately 90 horses and ponies for teaching and research. Three

research barns in the facility contain over 40 stalls and several pastures and paddocks are available for turnout and housing. We

have upgraded and added some key facilities and equipment, including the renaming and dedication of the EHSP physiology and

pharmacology laboratory as the Charles V. Cusimano Equine Physiology and Pharmacology Laboratory and the updating of the

Equine Performance Evaluation Laboratory and Lameness Pavilion, the Equine Cell and Tissue Culture Laboratory, the Laboratory

for Equine and Comparative Orthopedic Research, and the Equine Molecular Laboratory. Additionally, the clinical facilities and

equipment within the Veterinary Teaching Hospital and other core research facilities and resources within the LSU SVM support the

research activities of the EHSP.

Charles V. Cusimano Equine Physiology and Pharmacology Laboratory

Numerous faculty and graduate students conduct

scientific investigations involving equine physiology,

pharmacology, and pathophysiology, including but not

limited to vascular and nonvascular smooth muscle

physiology, pathology, and pharmacology (digital and

intestinal vasculature, bronchial, uterine and intestinal

smooth muscle), mucosal injury due to non-steroidal-anti-

inflammatory drugs, mucosal physiology and permeability,

endotoxemia, laminitis, and development and testing the

effects of medications on hemodynamics. We currently

have 15 Ussing’s chambers systems and multiple tissue

baths for measuring gastrointestinal mucosal permeability and injury and muscular contraction.

Ussing’s chambers for gastrointestinal permeability studies

58


Laminitis Research Laboratory

Pfeiffer-Burt Lameness and Performance Pavilion

The Pfeiffer-Burt Lameness and Performance Pavilion (75’ x 125’) is a modern facility for evaluation of locomotion in horses. Several

research projects evaluating the efficacy of pharmaceutical and nutraceutical agents and feed additives for treatment of lameness in

horses are being evaluated in this facility.

59


Lameness examination in the Pfeiffer-Burt Lameness and Performance Pavilion with force platform for objective measurement of lameness

Force Plate Analysis in the Pfeiffer-Burt Lameness and Performance Pavilion

60


Lameness Locator

Equine Performance Evaluation Laboratory

The Equine Performance Evaluation Laboratory (EPEL)

is equipped with a high-speed treadmill for exercising

horses at speeds that mimic racing conditions. A Coda

Motion System digital motion analysis system that

incorporates markers on the horse into digital images to

evaluate gait and lameness is also available (see image

below). Evaluation of the dynamics of the upper airway

can be achieved by a dynamic endoscopic system. The

dynamic endoscope can evaluate the upper airway in

research and clinic horses exercising on the high-speed

treadmill or working in their natural environment, such as

the racetrack or riding arena.

Dynamic Endoscope

61


Laboratory for Equine and Comparative Orthopedic Research

The Laboratory for Equine and Comparative Orthopedic

Research (LECOR) was established and designed to

facilitate a strong association between clinical and basic

orthopedic research for advancement of orthopedic

knowledge across species and disciplines. LECOR is

specifically designed and equipped for translational

orthopedic research from the molecular/genetic level to the

structural level.

The laboratory is equipped with the most modern

equipment for molecular/genetic work, including an MJ

Research Chromo4 Detector and DNA Engine 200 for DNA

fragment amplification and Quantitative PCR, a UVP hybrilinker for blot analysis and a Synergy HT multi-detection microplate reader

for ELISA assays. Housed within the laboratory is a Leica DM 4000 light microscope with fluorescent, polarizing and phase contrast

capabilities. The microscope is equipped with the latest in digital image capture equipment and software. Additionally, there is a

PathScan Enabler to obtain ultra high quality images from 1 x 3 inch glass slides. A custom-designed servohydraulic axial torsional

Material Testing System with a Flex Test SE Controller and equipped with a Multiple Gage Length Axial Extensometer makes

nearly any level of mechanical tissue testing possible, from the tissue and bone level to joint and whole limb testing. Presently,

several state-of-the-art diamond saws are available for both orthopedic hard and soft tissue microscopic and ultrastructural sample

preparation. A section of the laboratory is devoted to histologic preparation of both calcified and decalcified tissue samples. Areas

of research focus include the pathophysiology of hip dysplasia, the development and implementation of novel orthopedic devices

and cranial cruciate ligament disease. Also, the laboratory is active in equine stem cell research, regenerative medicine and tissue

culture. The laboratory focuses on translation of basic scientific research to the live horse. Projects within the laboratory include

growth of laminar cells for use as an in vitro model of laminitis and bone marrow stem cells for use in tendon healing.

Equine Orthopedics and Biomechanics

We have developed a solid research program in the area of equine orthopedics and biomechanics. This has led to the development

of numerous orthopedic implants designed specifically for equine use, which is critical for the advancement of equine orthopedics

and fracture repair. These equine specific orthopedic implants have distinct advantages over those intended for human application.

The EHSP is unique in that it is part of the only school of veterinary medicine in the country that is designing and testing equine

specific orthopedic implants. An integral part of this research program was the development of a finite element computer model

that allows for the biomechanical testing of an orthopedic implant applied to an equine bone or bones. This allows for changes in

implant design to be made and tested using the finite element model prior to in vitro biomechanical testing. This computer aided

design approach allows for more efficient use of the limited cadaver specimens. This research has direct and often immediate

clinical applications. We are presently advising and performing biomechanical tests on prototype large animal orthopedic implants

for Synthes Vet, Inc., Innovative Animal Products, and IMEX Veterinary, Inc.

Clinical Facilities and Equipment

The LSU Veterinary Teaching Hospital is staffed 24/7, 365 days a year with board certified and internationally recognized veterinary

specialists and highly-skilled veterinary technicians who provide clinical service to the horse-owning public.

62


Computed Tomography

The Veterinary Teaching Hospital’s Diagnostic Imaging

Service is equipped to provide its patients with clinical

diagnostic imaging. On-site diagnostic imaging includes

computed tomography, as well as Large and Small Animal

radiography, digital fluoroscopy, ultrasonography, magnetic

resonance imaging and nuclear scintigraphy.

MRI Unit

In 2009, the LSU Veterinary Teaching Hospital added a

state-of-the-art MRI unit for evaluation of soft tissue and

bony lesions in the head, neck, and limbs of horses with

hard to diagnose clinical conditions, including foot and

lower limb lameness.

Diagnostic and Research Endoscopy

The hospital has also added new digital endoscopy

equipment (Karl Storz, Inc.) to diagnose conditions of the

upper and lower airways, esophagus, stomach, proximal

duodenum and reproductive tract.

63

FACILITIES AND EQUIPMENTFACILITIES AND EQUIPMENT

Equine Reproduction/Theriogenology Laboratory

The Equine Reproduction/Theriogenology Laboratory

has complete facilities for the evaluation, chill-transport,

and cryopreservation of spermatozoa, including light and

phase-contrast microscopes and a computer-assisted

spermatozoal analysis system (Spermvision®). There are

three ultrasound machines with 5-7.5 MHz linear array

transducers and a 5-7.5 MHz sector array transvaginal

transducer for oocyte collection by follicular aspiration or

twin reduction by aspiration. A fourth ultrasound system

equipped with a 3.5 sector and 5-7.5 microconvex

array is available for transabdominal imaging. An

Olympus endoscope is also available for hysteroscopic

examination and for hysteroscopic low-dose insemination. Laparoscopy is available and used for oviductal insemination and for

minimally invasive placement of intrauterine catheters. We maintain a close collaborative relationship with the Equine Biotechnology

Laboratory, which is part of the LSU Agricultural Center. This facility has tissue culture laboratories and micromanipulators that make

possible such advanced assisted reproductive techniques as intracytoplasmic spermatozoal injection and nuclear transfer (cloning).

Equine Molecular Biology Research Laboratory

The Equine Molecular Biology Research Laboratory is equipped

to support the molecular biology aspects of research conducted

by the EHSP investigators. The missions of this laboratory are to

perform research to explain the molecular basis of disease with a

view to improved clinical approaches; to train scientists, students,

and visitors at all levels; and to develop new instruments and

methods in equine molecular biology. We also have direct access

to the core facilities within the LSU SVM Division of Biotechnology

and Molecular Medicine (BIOMMED) for quantitative Real-Time PCR,

primer/probe design, Quantity One for DNA fragment visualization

and analysis, SDS-PAGE analysis, MagnaPure automated nucleic

acid extraction, and microarray spotters and readers. Current

investigations utilizing this laboratory include study of key mediators

in equine laminitis, metabolic disease, gastrointestinal disease, summer pasture-associated recurrent obstructive airway disease,

bone healing and mechanisms of pain sensation and modulation. The capabilities of this laboratory have expanded in light of the

increasing importance of the molecular biological approach to the investigation of equine health and disease.

64

LAMINITIS

Assessment of Digital Venograms in Non-Laminitic Horses

Authors/Investigators

Britta Leise, DVM, PhD, DACVS, Nigel Miller, DVM, Valerie Moorman, DVM, PhD, DACVS, Luke Bass, DVM, MS, DAVBP, Sammy

Pittman, DVM, Amy Rucker, DVM, R.F. Redden, DVM

Date Issued

Presented in 2016 at the AAEP Annual Convention; Orlando, FL.

Introduction

Venography is frequently used to assess vascular perfusion in the hoof; however, interpretation of the venogram remains subjective

and can be challenging to veterinarians with limited experience performing venography.

Objective

The purpose of this study was to evaluate venographic technique in athletic, non-laminitic horses and to describe variations in the

pattern.

Methods

• Horses were evaluated for lameness, and survey radiographs were obtained for each foot. Survey radiographs were evaluated

for bone and hoof angle, palmar angle and sole depth.

• Venograms were performed in both front feet of 23 horses. The amount of contrast and time required for infusion was recorded

for each foot. Venograms were graded for contrast distribution throughout the digital vasculature.

• A total of 45 venograms in 23 horses were successfully performed.

• Amount of contrast infused in each foot averaged 22.9 mls.

• All venographic images were obtained within an average of 97 seconds post-infusion.

Results

• Fourteen feet had decrease contrast in the dorsal lamellar vessels on the early weight-bearing view, but contrast returned to this

region when viewed on the unweighted lateral.

• Variation in the venographic pattern can be related to hoof conformation and weight-bearing; however, full assessments can be

given if multiple views are obtained.

65

LAMINITIS

Take Home Message

Digital venography in horses without known digital pathology demonstrates slight variations in the vascular pattern of the equine

foot. Obtaining a full series of images, including early and late lateral views and weight-bearing and non-weight bearing images are

necessary when assessing the vascular pattern in all horses.

Venogram image obtained immediately post digital venous perfusion with

24 ml of radiographic contrast agent.

Use of Laser Capture Microdissection for the Assessment of Equine Laminar Basal Epithelial Cell Signaling in the Early Stages of Laminitis


Britta Leise, DVM, PhD, DACVS; Mauria Watts; Sashwati Roy, PhD; Selen Yilmaz; Hansjuerg Alder, PhD; James Belknap, DVM, PhD,

DACVS

Date Issued

Published in Equine Vet J. (2015) 47:478-488

Introduction

The central event leading to structural failure of the lamina in equine laminitis is the detachment of the laminar basal epithelial cell

(LBEC) from the basement membrane. As epithelial cell signaling is central to organ dysfunction and failure (i.e., kidneys, lungs) in

human sepsis, we hypothesized that LBEC signaling plays a similar role in laminar failure in equine sepsis-related laminitis.

66

LAMINITIS

66

Objective

The objective of this study was to isolate LBECs from laminar tissue using LCM techniques and subsequently identify genes involved

in LBEC dysfunction during the early stages of carbohydrate (CHO)-induced laminitis.

Methods

• Laser capture microdissection (LCM) was used to isolate LBECs from cryosections obtained from laminar biopsy samples taken

prior to (CON), and 24 (DEV) and 48 h (OG1) following experimental carbohydrate (CHO) overload in eight horses.

• Broad transcriptome analysis (RNA-Seq) was used to identify genes and signaling events occurring in LBECs.

• Forty genes (22 increased/18 decreased) were differentially expressed at the DEV time, and 107 genes (57 increased/50

decreased) were differentially expressed at the OG1 time compared to CON.

• On bioinformatics analysis, the major signaling pathways induced at the two time points were those involved in inflammatory

signaling and regulation of extracellular matrix.

• Inflammatory signaling in the LBEC included increased expression of cytokines, monocytic chemokines, Toll-like receptors and

multiple enzymes involved in prostanoid synthesis.

• Matrix signaling included upregulation of matrix metalloproteases and decreases in matrix proteins important in maintaining

stability at the epidermal/dermal interface in other species, including small leucine rich proteoglycans (biglycan, decorin, lumican,

fibromodulin) and collagen XIA1.

Results

The results demonstrate that the LBEC is not just a casualty but an active participant in laminar events leading to structural failure in

laminitis.

Laser capture microdissection from equine lamina (hoof tissue). A) section of

laminar basal epithelial cell (LBEC) are selected from 10x microscopic images. B)

laser is used to cut the selected tissue from the microscope slide. C) cut section is

catapulted into an adhesive cap and collected for gene expression analysis.

67

STEM CELLS

Optimized Adult Equine Multipotent Stromal Cell Osteogenesis with Customized Scaffolds and Perfusion Bioreactor Culture


Wei Duan, Carmel Fargason, Mandi J. Lopez, Department

of Veterinary Clinical Sciences, LSU SVM

Introduction

A tissue engineering approach to restore damaged

equine bone represents a promising alternative to

current therapeutic strategies. The proposed approach

involves selection of adipose derived-multipotent

stromal cells (ASCs) that have the best potential for

bone generation in combination with a scaffold carrier.

The most common method to isolate ASCs from

adipose tissue is collagenase digestion. However,

collagenase may hydrolyze proteins, leave foreign

protein residues and change surface marker expression.

The ideal digestion mixture has the lowest collagenase

concentration and the highest ASC yield. Additionally,

primary ASCs isolates contain numerous subpopulations

with distinct behaviors. Specific immunophenotypes

may have more predictable clinical behavior. To achieve

the best osteogenic outcomes, the ideal scaffold must

be identified, and our previous work confirmed poly-l-

lactic acid (PLLA) and polyethylene glycol (PEG) support

ASC attachment and osteogenic differentiation. Culture

conditions should support cell viability while promoting

osteogenesis. We sought to design a custom perfusion

bioreactor system in which culture medium and cells

pass through the internal porous network of scaffold

carriers. This culture system mitigates internal diffusion

limitations inherent to large tissue constructs.

Objectives

The objectives of this study were to optimize equine ASC isolation and, subsequently, select ASC immunophenotype subpopulations

with the best osteogenic capacity. We also planned to enhance decellularized/deproteinized trabecular bone with custom,

osteogenic coatings and to design and build a custom perfusion bioreactor system, both for optimal equine ASC osteogenesis. Our

ultimate goal is to develop viable bone tissue grafts from individual ASCs.

68

STEM CELLS

Methods

The stromal vascular fraction (SVF) was equally divided into two equal portions. Specific cell immunophenotypes were selected

from one portion while the entire cell population in the other portion was utilized. Both portions were evaluated up to cell passage

3. Outcomes for both cohorts included cell ultrastructure and surface antigen expression, as well as viability, proliferation and

plasticity. To make customized scaffolds, the osteogenic surface coating materials PLLA and PEG at ratio of 60:40 were used to coat

deproteinized/decellularized equine trabecular bone scaffolds through physical adsorption. Pore size was maintained at 300µm,

a size found to support differentiation and extracellular matrix (ECM) production by undifferentiated cells. Adult equine ASCs were

loaded onto coated, deproteinized/decellularized trabecular bone scaffolds using a customized perfusion bioreactor. The cells

were counted immediately after loading, and the constructs evaluated after seven, 14 and 21 days of static culture in osteogenic

or stromal medium. Constructs were evaluated for cell number, morphology, extracellular matrix deposition, viability, distribution,

osteogenic differentiation, osteogenic target gene mRNA levels and protein expression at each time point.

Results

The equine ASC immunophenotype MHCI-, CD44+, and CD105+ shows comparable calcium deposition and lipid droplet formation

compared to unsorted cells following seven days of culture in osteogenic and adipogenic induction medium, respectively. The

equine ASC immunophenotype has significantly higher osteoblastic and adipocytic colony forming unit frequency percentages than

unsorted cells and there is no detectable effect of collagenase type I concentration in the tissue digestion solution. Customized

polymer coating materials were distributed throughout the scaffold surface.

Figure 1. Unsorted, CD44+, CD105+, MHCII+ or MHCII- equine ASCs have similar fibroblastic (CFU-F) , osteoblastic (CFU-Ob), and

adipogenic (CFU-Ad) differentiation capabilities.

Figure 2. The customized polymer coating materials were distributed

throughout the deproteinized/decellularized trabecular bone scaffold.

Take Home Message

There are no differences in cell expansion, plasticity or surface protein expression among ASCs isolated from adipose tissue with

different collagenase concentrations. Unsorted cells have significantly higher expansion rates but lower differentiation potential than

ASCs that are CD44+, CD105+, and MHCII + or -. Differences in behavior between sorted and unsorted cells confirm the importance

of using specific ASC immunophenotypes for clinical applications to help ensure the most predictable clinical outcomes.

69

STEM CELLS

Funding

This study was funded by a Charles V. Cusimano Equine Health Studies Program grant, Equine Health Studies Program (EHSP),

Louisiana State University School of Veterinary Medicine. The authors declare no conflicts of interest.

Year Completed

In progress

Isolation and Characterization of Equine Hoof Stem Cells


Qingqiu Yang1, Mandi J Lopez1, Catherine Takawira2

1Laboratory for equine and comparative orthopedic research; 2Department of veterinary clinical science, LSU SVM; 3Equine health

study program, LSU SVM

Introduction

Every year, laminitis results in great expense and loss of equine companions. Our novel area of investigation is the relationship

between laminitis and equine hoof stem cells. Specifically, we seek to develop a laboratory model to study the effects of laminitis on

equine hoof stem cells and to develop therapies to prevent or treat hoof damage.

Objectives

The purpose of this study is to isolate and characterize stem cells from both unaffected and laminitic hooves, including a transitional

stem cell that is unique to the hoof. We hypothesize that the immunophenotypes and expansion rate of equine hoof stem cells are

changed during laminitis.

Methods

Hooves were harvested from five horses with laminitis and five horses without laminitis euthanatized for reasons unrelated to this

study. Laminar tissue was harvested from hooves, and stem cells were isolated via collagenase digestion.

Cell expansion rate and plasticity were quantified with cell doubling and colony forming unit frequency (CFU) assays, respectively.

Quantitative real time PCR, flow cytometry, immunohistochemistry and immunocytochemistry techniques were used for cell

immunophenotype identification. Flow cytometry was also used to isolate transitional stem cells with both epidermal and

mesodermal markers. The differentiation ability of stem cells, including transitional stem cells, from unaffected and laminitic hooves

was quantified with adipogenesis and osteogenesis differentiation assays. Cell ultrastructure was evaluated with transmission

electron microscopy (TEM).

70

STEM CELLS

Results

Cell morphology and expansion rates are similar between stem cells from unaffected and laminitic hooves. Stem cells from both

unaffected and laminitic hooves express CD29, CD105, CD44, and K15, which is also expressed by cells in situ. Transitional stem

cells are also present in unaffected and laminitic hoof tissue.

Transitional stem cells show better adipogenic and osteogenic differentiation than unsorted cells. Elongated mitochondria and

abundant rough endoplasmic reticulum in TEM images indicate a high metabolic capacity of transitional stem cells.

Figure 1: Experimental Outline

Take Home Message

We have successfully isolated and cultured stem cells from normal and laminitic equine hoof tissue. Cells from normal and affected

hooves are morphologically similar; however there are some differences in stem cell immunophenotype percentages between the

two conditions. We isolated transitional stem cells from normal and affected tissue that have promising regenerative capacity. Future

studies will focus on further characterization of this stem cell type to target laminitis prevention and treatment strategies.

References

1. Koch TG, Berg LC, Betts DH. Current and future regenerative medicine - principles, concepts, and therapeutic use of stem cell

therapy and tissue engineering in equine medicine. The Canadian Veterinary Journal. La Revue Veterinaire Canadienne 2009; 50:

155-65.

71

STEM CELLS

2. Frisbie DD, Kisiday JD, Kawcak CE et al. Evaluation of adipose-derived stromal vascular fraction or bone marrow-derived

mesenchymal stem cells for treatment of osteoarthritis. Journal of Orthopaedic Research: Official Publication of the Orthopaedic

Research Society 2009; 27: 1675-80.

3. Tarnok A, Ulrich H, Bocsi J. Phenotypes of stem cells from diverse origin. Cytometry. Part A : The Journal of the International

Society for Analytical Cytology 2010; 77: 6-10.

4. Webb A, Kaur P. Epidermal stem cells. Frontiers in bioscience: A Journal and Virtual Library 2006; 11: 1031-41.

5. multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8:

315-7.

6. Metcalfe AD, Ferguson MW. Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic

development, stem cells and regeneration. Journal of the Royal Society, Interface/The Royal Society

7. Morrison, S., Dryden, V. C., Bras, R., & Morrell, S. (2014). How to use stem cells in clinical laminitis cases. In Proceedings of the 60th

Annual Convention of the American Association of Equine Practitioners, Salt Lake City, Utah, USA, December 6-10 2014 (pp. 499-

503). American Association of Equine Practitioners (AAEP) Funding

Funding

This study was funded by a Charles V. Cusimano Equine Health Studies Program grant, Equine Health Studies Program (EHSP),

Louisiana State University School of Veterinary Medicine. The authors declare no conflicts of interest.

Acknowledgements

Special thanks to Michael Keowen and Marilyn Dietrich for their help with this project.

72

GASTROINTESTINAL HEALTH

Effects of Metronidazole and Flunixin Meglumine on Equine Right Dorsal Colonic Mucosa


K. Shell, C. Koch, F. Del Piero, R. McConnico. Dept. of Veterinary Clinical Sciences and Dept. of Pathobiological Sciences, Louisiana

State University, School of Veterinary Medicine, Baton Rouge, LA.

Introduction

One of the overall goals for the Charles V. Cusimano Equine Physiology

and Pharmacology Laboratory is collaborative research relating to

gastrointestinal diseases. Acute equine colitis is an example of a

frequent cause of rapid, severe, debilitation and death in horses where

over 90 percent of untreated horses die or require euthanasia. Horses

that are treated appropriately will usually respond and gradually

recover over a seven to 14 day period. Acute equine colitis-associated

diarrhea is sporadic in occurrence and is characterized by intraluminal

sequestration of fluid, moderate-to-severe colic, and profuse watery

diarrhea, with resultant endotoxemia, leukopenia, and hypovolemia.

The condition can affect adult horses of all ages, but usually occurs in

horses between the ages of 2 and 10 years. Disease onset is sudden

with rapid progression and is often preceded by a stressful event. A

definitive diagnosis is made in only about 20-30 percent of cases. Most

ante- and post-mortem diagnostic tests to determine etiology remain

speculative. Treatment of the condition in horses is extremely costly

because of the substantial volumes of intravenous fluid required. At

present, there is no curative treatment for acute diarrhea in horses, and

treatment strategies are directed at rehydration, electrolyte and plasma

protein replacement, anti-endotoxemia therapy, and antimicrobial

therapy when indicated.

Metronidazole (MZ) and flunixin meglumine (FM) are commonly

used drugs for treating equine colitis. While the potential of FM to

contribute to the pathophysiology of colitis has been known for

a while, effects of MZ on the intestinal mucosa are controversial

and have not been studied in horses. The aim of this study was to

investigate the effect of FM, MZ and a combination of these drugs

on the equine colonic mucosa.

Objective

To determine the effect of metronidazole and flunixen meglumine

on mucosal permeability, goblet cell depletion and thinning of the

mucosal layer of the equine colon.

73


Methods

Equine right dorsal colonic tissue of 10 horses being euthanized for natural unrelated diseases was studied in Ussing chambers.

Tissue was treated with therapeutic dosages of MZ, FM, combined MZ and FM, or no medication (negative control). Transepithelial

resistance (TER) as an indicator of tissue permeability, and direct measurement of mucosal to serosa fluxes with fluorescein labeled

LPS were recorded. Histological tissue evaluation was performed.

Results

Treatment of equine dorsal colonic with MZ did not increase colonic mucosal tissue permeability. Increased tissue permeability due

to treatment with FM was decreased with a combined treatment with MZ, thus suggesting a protective effect. The mucous layer of

the colon remains intact with MZ treatment, but not with FM alone.

Take Home Message

Systemic metronidazole treatment may provide

protection to equine colonic mucosa in cases of

acute colitis in horses treated with or without flunixen

meglumine.

References

Bjarnason, I., Hayllar, J., Smethurst, P., Price, A.,

Gumpel, M.J.: Metronidazole reduces intestinal inflammation and blood loss in non-steroidal anti-inflammatory drug induced

enteropathy. Gut. 1992 Sep;33(9):1204-8.

Campbell, N.B., Jones, S.L., Blikslager, A.T.: The effects of cyclo-oxygenase inhibitors on bile-injured and normal equine colon. Equine

Vet J. 2002 Jul;34(5):493-8.

McConnico, R.S., Koch, C.E., Paulsen, D.B., Andrews, F.A., Effect of COX1-inhibitor and COX1-sparing drugs on equine right dorsal

colon in vitro, 2011 http://www.aaep.org/images/files/EffectCOX1inhibitorandCOX1sparingdrugsequinerightdorsal.pdf

McConnico, R.S., Stokes, A.M., Eades, S.C., Moore, R.M., Investigation of the effect of black walnut extract on in vitro ion transport

and structure of equine colonic mucosa. Am J Vet Res. 2005 Mar;66(3):443-9.

McGorum, B.C., Dixon, P.M., Smith, D.G.E.: Use of metronidazole in equine acute idiopathic toxaemic colitis. Vet Rec. 1998 Jun

6;142(23):635-8.

Steinman, A., Gips, M., Lavy, E., Sinay, I., Soback, S.: Pharmacokinetics of metronidazole in horses after intravenous, rectal and oral

administration. J Vet Pharmacol Ther. 2000 Dec;23(6):353-7.

Wlodarska,M., Willing,B., Keeney, K.M., Menendez, A., Bergstrom, K.S., Gill, N., Russell, S.L., Vallance, B.A., Finlay, B.B.: Antibiotic

treatment alters the colonic mucus layer and predisposes the host to exacerbated citrobacter rodentium-induced colitis. Infect

Immun. 2011 Apr;79(4):1536-45.

74


Acupuncture and Therapeutic Massage Treatment and The Attenuation of Salivary Cortisol Levels in The Domestic Horse


SE Gautreaux, C Koch, NH Walker, and RS McConnico. Equine Health Studies Program, School of

Veterinary Medicine, Louisiana State University, Baton Rouge, LA

Introduction

Stress continues to be a concern for horses used for human pleasure. The goal of this study was

to determine effective methods for stress reduction in the practice of equine well-being. Both

acupuncture and therapeutic massage have been proven to reduce stress in humans; however,

evidence based research is needed to support its use in equine veterinary medicine.

Objective

To determine if acupuncture and/or therapeutic massage may be an effective method of reducing stress in the adult horse by

evaluating salivary cortisol levels as an indirect measure of stress levels in pastured adult horses.

Methods

Twelve horses from the LSU School of Veterinary Medicine teaching herd were evaluated in a controlled cross over study. Twelve

horses were divided into three groups of four and rotated between four treatments (1) acupuncture, 2) deep tissue massage and 3)

grooming only. Treatment sessions lasted for two weeks each. Horses in each respective group received designated treatments

two times per week and saliva was collected as a means to indirectly measure cortisol levels after treatment using a snaffle bit with

cotton and plastic webbing left in place for 35 minutes. In addition, saliva was collected from each horse three days pre- and post-

each treatment session. Salivary cortisol was measured using a cortisol enzyme immunoassay and with samples run in duplicate.

Results

There is marked Individual animal variability both within and between animals

that require additional animal numbers for the determination of statistical

significance in this study. However, when animals were assessed individually,

there was a trend for decreased cortisol production between time 0 (pre-

sample) and either first, second, or both treatment sessions during the first

week of treatment. The study also suggests the salivary cortisol values can be

a useful and non-invasive test in determining treatment differences in stress in

horses.

Take Home Message

Acupuncture therapy and/or therapeutic massage may be an effective method for reducing stress in healthy individual horses.

75


References

Lansade L, Valenchon M, Foury A, Neveux C, Cole SW, Layé S, Cardinaud B, Lévy F, Moisan MP. Behavioral and Transcriptomic

Fingerprints of an Enriched Environment in Horses (Equus caballus). PLoS One. 2014 Dec 10;9(12).

Smiet E, Van Dierendonck MC, Sleutjens J, Menheere PP, van Breda E, de Boer D, Back W, Wijnberg ID, van der Kolk JH Effect of

different head and neck positions on behaviour, heart rate variability and cortisol levels in lunged Royal Dutch Sport horses. Vet J.

2014 Oct;202(1):26-32.

Wang SJ, Zhang JJ, Qie LL. Acupuncture Relieves the Excessive Excitation of Hypothalamic-Pituitary-Adrenal Cortex Axis Function

and Correlates with the Regulatory Mechanism of GR, CRH, and ACTHR. Evid Based Complement Alternat Med. 2014:495379. doi:

10.1155/2014/495379. Epub 2014 Mar 11

Nuñez CM, Adelman JS, Smith J, Gesquiere LR, Rubenstein DI. Linking social environment and stress physiology in feral mares

(Equus caballus): group transfers elevate fecal cortisol levels. Gen Comp Endocrinol. 2014 Jan 15;196:26-33

Fureix C, Benhajali H, Henry S, Bruchet A, Prunier A, Ezzaouia M, Coste C, Hausberger M, Palme R, Jego P Plasma cortisol and

faecal cortisol metabolites concentrations in stereotypic and non-stereotypic horses: do stereotypic horses cope better with poor

environmental conditions? BMC Vet Res. ;9:3. 2013 Jan 7.

Fureix C, Jego P, Henry S, Lansade L, Hausberger M Towards an ethological animal model of depression? A study on horses. PLoS

One. 2012;7(6):e39280. doi: 10.1371/journal.pone.0039280. Epub 2012 Jun 28.

Malinowski, K Stress Management for Equine Athletes Rutgers Cooperative Extension Fact Sheet.

Haussler KK. Vet Clin North Am Equine Pract. 2010 Dec;26(3):579-601. doi: 10.1016/j.cveq.2010.07.006. Review. The role of manual

therapies in equine pain management.

Luna SP, Angeli AL, Ferreira CL, Lettry V, Scognamillo-Szabó M. Comparison of pharmacopuncture, aquapuncture and acepromazine

for sedation of horses. Evid Based Complement Alternat Med. 2008 Sep;5(3):267-72.

76


Authors: M.E. Gordon¹, M.L. Jerina¹, J.K. Young¹, F.M. Andrews²

¹Purina Animal Nutrition, Gray Summit, MO, USA; ²Louisiana State University,

Baton Rouge, LA, USA.

Presented at the Minnesota Equine Nutrition Conference.

77


78


Authors: Mary E Gordon, Kelly R Vineyard, Michael Keowen, Frank Garza, Jr.

Frank M Andrews.

Purina Animal Nutrition, Gray Summit, MO, USA

Louisiana State University, Baton Rouge, LA, USA

79


80


Effects of Hydrolyzed Collagen on Equine Gastric Ulcers Scores and Gastric Juice pH in Horses

Frank M. Andrews¹, Pilar Camacho-Luna¹, Lisa Micheau², Michael L. Keowen¹, Frank Garza, Jr.¹, Chin-Chi Liu¹, Brian Lamp³, Jos Olijve⁴

¹ Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State

University, Baton Rouge, LA, USA

² Ecole Nationale Veterinaire De Toulouse, Toulouse, France

³ Sonac - Darling Ingredients, Mukwonago, Wisconsin ,USA

⁴ Sonac - Darling Ingredients, Son, The Netherlands

Introduction

Horses have a compound stomach (Fig 1), and up to 90% of performance horses suffer from gastric ulcers. Omeprazole (Gastrogard®,

Merial LTD, Duluth, GA) is FDA-approved in the US for treating gastric ulcers. However, it is expensive and must be given daily

during training and racing, which most performance venues do not allow. In addition, ulcer recurrence is common after discontinuing

treatment. Thus, the development of effective management

strategies and natural feed supplements to prevent ulcer

recurrence and promote stomach health is needed. Hydrolyzed

collagen (HC) (Darling Ingredients, Irving, TX, USA) is a supplement

containing bioactive peptides and Type 1 Collagen, which

promotes gastric health.

The purpose of this study was to evaluate the effect of hydrolyzed

collagen (HC) on ulcer scores and gastric juice pH in stall-confined

horses.

Hypothesis

Hydrolyzed collagen (HC) prevents the worsening of gastric ulcers in stall-confined horses after omeprazole treatment and

intermittent feeding, without long-term alteration of gastric juice pH.

Methods

Thoroughbreds (n=10) were moved to stalls and subjected to two treatments in a 56-day two period crossover study timeline (Fig

2). One group received 45g HC (Mw 2.5kDa from porcine bone, Sonac) mixed with 1kg sweet feed (Omelene 100, Purina Animal

Nutrition). The control group (C) received 1kg sweet feed only. The sweet feed and mixed grass hay (1.5% body weight) was given

twice daily for two 56 days periods. From day 14-28, both groups received omeprazole (4.0mg/kg). From day 42-49, horses

underwent a feed-deprivation period, to induce ulcers. Gastroscopy (Fig 3) was performed on day -1 (before treatment) and days

14, 28, 42, 49 and 56. Gastric juice was aspirated and pH was measured at each scoping. Nonglandular gastric ulcer number

(NGN) and severity (NGS) scores, 0 (no) to 5 (severe) were assigned by a masked investigator (FMA) (Table 1). ANOVA for repeated

measurements and a post-hoc Tukey test were used to determine significant differences, P < 0.05.

81


Results

HC, mixed with grain, was readily eaten by all horses, and did not

result in any adverse effects.

There was a period effect and data was pooled for statistical

evaluation.

Overall, mean gastric ulcer scores were lower during Period 2 of

the study, due to acclimation to stalls.

Mean NGS and NGN gastric ulcer scores were lower at each

gastroscopy examination and a significant treatment effect was

seen in NGN on day 56 of the study (Figs 5).

Gastric juice pH values were low and variable throughout the trial, except

on day 28 when pH was significantly higher in HC supplement-treated

group compared to control group while on omeprazole treatment.(Fig 6).

Discussion and Conclusions

Hydrolyzed Collagen-fed horses had fewer and less severe

ulcers throughout the trial and significantly fewer ulcers

were seen after 56 days of feeding.

Hydrolyzed Collagen ameliorated the severity of gastric

ulcers in stall-confined horses undergoing stall confinement

and feed stress (Fig 7).

Acknowledgments

The authors thank the technicians, lab assistants, and

student workers who supported this study. Funding for

this study was provided by Darling Ingredients, the Equine

Health Studies Program (EHSP), Louisiana State University

School of Veterinary Medicine.

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Figures

Fig 1. Compound equine stomach, showing the

glandular and nonglandular regions.

Fig 2. Timeline for Period 1, whereby horses

were scoped on days 0, 14, 28, 42, 49, and

56. The period was repeated after at least

a 2-week washout, with the treatment and

control groups switched, so that each horse

served as his own control.

Fig 3. Horses were first sedated with xylazine.

Then, gastroscopies were performed using a 3

m endoscope (Karl Storz, El Segundo, CA).

Fig 5. Mean Nonglandular Severity Score (NGS; 0-5) on Day 0 (before) and Days 14, 28, 42, 49 and 56 of feeding Hydrolyzed

Collagen (Collagen; 45 g, mixed in grain twice daily). Horses were given omeprazole paste (4.0 mg/kg, orally, once daily), Day 14 to

28 and exposed to an alternating feed deprivation model from Days 42 to 49. Different lower case letters denote significant day

(P<0.05) differences.

Fig 6. Mean endoscopic nonglandular number score (NGN 0-4) in horses on Day 0 (before) and Days 14, 28, 42, 49 and 56 after

feeding HC (45 g, mixed in grain twice daily). Horses were given omeprazole paste (4.0 mg/kg, orally, once daily) from Day 14 to

28 and horses were exposed to an alternating feed deprivation model from Days 42 to 49. Different lower case letters denote

significant (P<0.05) day and treatment*day differences.

Fig 7. Mean gastric juice pH in horses on

Day 0 (before) and Days 14, 28, 42, 49 and

56 after feeding HC (45 g, mixed in grain

twice daily). Horses were given omeprazole

paste (4.0 mg/kg, orally, once daily) from

Days 14 to 28 and horses were exposed

to an alternating feed deprivation model

from Days 42 to 49. *denotes a significant

treatment by day effect and a denotes a

significant day effect.

83


Fig 8. Gastroscopic pictures of the

nonglandular region of the stomach on

days 0, 14, 28, 42, and 56. Nonglandular

Ulcer Number score was significantly

(P<0.05) lower in HC-treated horses by

Day 56. Also, ulcer scores decreased in

both the treatment and control horses

after omeprazole treatment (day 28).

84

HOSPITAL MANAGEMENT

Elimination of the Use of Rubber Stall Mats for Effective Intervention of Nosocomial Salmonella Enterica Spp. Infection in a Veterinary Teaching Hospital


RS McConnico, RW Stout, FM Andrews, AF Roy, Dept. of Veterinary Clinical Sciences, Dept. of Pathobiological Sciences, School of

Veterinary Medicine, Louisiana State University.

Introduction

Outbreaks of nosocomial Salmonella infections in

hospitalized horses can occur when surveillance and

infection control protocols are either not in place or not

implemented well. Over the past few decades multiple

scenarios have been reported where referral hospitals,

predominantly veterinary teaching institutions, have

experienced the consequences associated with patient

hospital-acquired infection (HAI) such as increased

morbidity or mortality, zoonotic infections, hospital

closings, and declining case-loads due to poor publicity.

The overall objective of this report is to show the

importance of facility management in an equine hospital

biosecurity program specifically as it relates to providing

cleanable stall flooring.

Methods

A nosocomial outbreak involving two serovars of Salmonella enterica spp. (serovars Javiana and Agona) in a population of

hospitalized horses resulted in re-evaluation of current hospital biosecurity measures in the large animal section of the LSU

Veterinary Teaching Hospital (VTH). Evaluation of the VTH Salmonella patient and environmental surveillance and tracking

information was suggestive of certain trouble spots with repeated positive environmental and patient fecal samples. Interventional

control measures included re-evaluating the standard operating biosecurity procedures, ensuring appropriate training sessions for

hospital personnel, re-evaluating and modifying bedding and manure disposal, removing items considered to be non-cleanable,

painting the interior of the facility with a nontoxic readily cleanable epoxy-type paint, replacement of stall walls with cleanable

synthetic surfaces, and removing the non-cleanable rubber stall mats. These changes had previously been instituted in the equine

and large animal intensive care unit, except for the elimination of the rubber stall mats.

Results

When rubber stall mats were removed and replaced with a poured flooring material,

the outbreak situation in the ICU was able to be controlled, and, subsequently, the

main large animal hospital patient housing and care areas. Prevention of nosocomial

infection requires a multifaceted approach and care must be taken to search out

covert sources of contamination, such as the rubber stall mats, when standard

intervention procedures do not prevent spread of the disease.

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HOSPITAL MANAGEMENT

Take Home Message

Prevention of nosocomial infection is multi-modal and requires continued awareness,

a committed team-oriented approach and strict enforcement of biosecurity policies

and procedures. Rubber mats may deteriorate and warrant closer inspection as a

possible source of environmental Salmonella contamination.

References

1) Dargatz DA, Traub-Dargatz JL. Multidrug-resistant Salmonella and nosocomial infections. Vet Clin North Am Equine Pract. 2004,

Dec;20(3):587-600.

2) Ekiri AB, et al. Review of the epidemiology and infection control aspects of nosocomial Salmonella infections in hospitalized

horses. Eq vet. Educ. 2010, 22 (12) 631-641.

3) Burgess BA, Morley PS. Managing Salmonella in equine populations, Vet Clin North Am Equine Pract.2014, Dec;30(3):623-40.

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SURGERY

Assessment of tuber coxae bone biopsy in the standing horse


Colin Mitchell, BVM&S, MS, Dipl. ACVS, Department of Veterinary Clinical Sciences; Margaret A. McNulty, PhD, Department of

Comparative Biomedical Sciences; Heather Richbourg, Department of Comparative Biomedical Sciences; Ashley Gillett, 4th-year

student; Brad Goupil, Department of Comparative Biomedical Sciences; School of Veterinary Medicine, Louisiana State University

Introduction

Equine bone structure and function can be evaluated for clinical or research investigation of pathologic, pharmacologic and

physiologic processes. Noninvasive diagnostic techniques are reported but provide insufficient samples for assessment of

bone architecture, or measurements of remodeling and mineral apposition. Invasive bone biopsies remain the gold standard for

quantitative assessment of bone remodeling, and efforts have previously been made to find the least invasive method to obtain

adequate bone samples from horses. Samples must be large enough for the architecture to be undamaged by the biopsy technique,

must provide enough tissue for multiple histologic sections to be examined and be of sufficient quality to assess trabecular and

cortical bone.

The tuber coxa is easily accessible, with minimal soft tissue coverage, and biopsy from this area has been described in cadaveric

or standing horses using specialized equipment; however, samples were not consistently of adequate histologic quality. The live

horses had minimal morbidity associated with the procedure. The contralateral tuber coxa can be biopsied at a future time point if

sequential samples are necessary to monitor or identify changes in remodeling or architecture, or for pharmacologic investigation.

Since the tuber coxa is a non-weight bearing region, an aggressive bone biopsy to obtain a larger sample can be performed without

the risk of disrupting function.

The objective of this study is to describe a technique of bone biopsy from the tuber coxae in standing horses using an oscillating

saw that provides a larger biopsy than previously

described using core trephine techniques. We propose

the biopsy will have intact, undamaged cortical and

trabecular architecture and be of sufficient size to allow

examination of multiple sections. We propose that this

technique will be associated with minimal morbidity in

horses.

Experimental Design

Ten young horses (<5 years of age) will be used for

this study. Unilateral biopsy of the tuber coxae will be

performed on each horse on Day 0. The horses were

monitored overnight in a stall, before being turned out

to pasture. At Day 60, the second biopsy was obtained

from the contralateral tuber coxae with similar exercise

restrictions post biopsy.

Biopsy in standing horse

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SURGERY

The biopsy technique was performed using sedation and local anesthesia. A 6-8 cm, vertically oriented skin incision was made with

its mid point over the palpable portion of the proximal tuber coxa. A combination of sharp and blunt dissection was used to expose

the tuber coxa on its cranial, caudal, proximal and axial margins. The periosteum was incised, and an oscillating saw was used to

transect the protuberance of the tuber coxa, at least 1cm distal to the proximal edge.

The saw blade was continuously lavaged with saline to limit thermal injury to the bone. The excised section of bone representing

the biopsy was at least 1 cm tall, with the width and length of the biopsy dependent on each horse’s pelvic anatomy. The goal was

to obtain the largest biopsy possible without cutting into the iliac crest on the axial border of the tuber coxa. The surgery site was

lavaged, and the biopsy site was sutured.

The biopsies were fixed in 10 percent formalin, and all were prepared for MicroCT examination. Day 0 biopsies were also prepared

for decalcified histology and the Day 60 biopsies were also prepared for undecalcified histology. All sections were evaluated under

light microscopy and, using a semi quantitative scale, were graded to be of useless, poor or good quality.

Results

All of the horses tolerated the procedure well and displayed minimal morbidity following the procedures. One surgical site (1/20

biopsy sites) dehisced shortly after the biopsy but was managed with local wound care. This proceeded to heal uneventfully.

No horses displayed any signs of moderate pain or lameness on the biopsied limbs at any time over the study period. MicroCT

evaluation was possible in all samples, with large amounts of intact trabecular and cortical bone present. The mean biopsy volume

was 3123.72 mm3. Histologic evaluation of the samples was possible and adequate for examination of cortical and trabecular bone

in both decalcified and undecalcified preparations.

Take Home Message

This biopsy technique was well tolerated by the horses and was associated with minimal morbidity. This technique provides a

considerably larger sample of bone with significantly fewer complications than other currently performed techniques. The biopsies

collected in this study were able to be evaluated using multiple techniques and were all of diagnostic quality, indicating that this is a

viable biopsy technique for researchers investigating bone remodeling, healing or performing pharmacologic studies.

Funding

Funding for this project was provided by the Charles V. Cusimano Equine Health Studies Program.

Year Completed

2014-2016.

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SURGERY

Influence of clodronate on bone density and bone formation in young horses



Comparative Biomedical Sciences; Heather Richbourg, Department of Comparative Biomedical Sciences; School of Veterinary

Medicine, Louisiana State University

Introduction

Orthopedic disease is a major performance limiting problem for equine athletes. Analgesics, anti-inflammatories, regenerative

therapies and supplements are all routinely used to try and help maintain, correct or prevent injury from occurring. New therapies are

being investigated, and clodronate is one that has demonstrated some beneficial effects on horses with navicular disease.

Clodronate is a bisphosphonate drug that was investigated as a treatment for diseases such as Paget’s disease or osteoporosis in

humans but has now been replaced by more potent alternatives. These diseases result in an uncoupling of the remodeling process,

with osteoporosis leading to a decrease in overall bone density, whereas Paget’s disease initially starts as a resorptive disease with

further complications following production of excessive, disorganized new bone. When administered, clodronate has been shown

to inhibit bone resorption by causing osteoclast apoptosis and disrupting the formation and secretion of proinflammatory mediators.

This reduction in proinflammatory mediators may be what causes the analgesia that has been observed in human patients treated

with this drug.

Histopathology and histomorphometry have been performed on multiple species treated with clodronate, at varying doses and

durations. Clodronate, like tiludronate, was able to ameliorate the decreases in bone mineral density following various surgical or

pharmacologic treatments in other species. No histopathologic or histomorphometric study has been performed in horses, and, since

this drug is being more widely used in a clinical setting, including young horses

to treat navicular disease or bone pain, the effects on normal bone remodeling in

horses should be investigated.

Experimental Design

Ten young horses (<5 years of age) will be used for this study. Five horses will

be in the treatment group and will receive clodronate, with the other five being

treated with a placebo (saline). Unilateral biopsy of the tuber coxae will be

performed on each horse. After collection of the first biopsy, clodronate (1.8mg/

kg) will be administered IM. The control group will receive only saline. The horses

will then be placed in a stall in the research barn overnight for monitoring, before

being turned out the following morning. Thirteen days prior to the second biopsy,

oxytetracycline (25mg/kg IV) will be administered. This dose of oxytetracycline

will be repeated three days prior to the second biopsy being performed. Sixty

days after clodronate administration, we will collect the second biopsy, from the

contralateral tuber coxae. The original tuber coxae will be biopsied again using

an identical approach to evaluate the effects following 60 days of healing, which Micro CT of bone

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SURGERY

is an additional component of this study. The biopsy procedure and the sample processing techniques are described in more detail

in the abstract “Assessment of tuber coxae bone biopsy in the standing horse.”

Results

At this time we are still analyzing the collected data, and no results regarding the impact of the drug on bone remodeling and healing

are available.

Take Home Message

This treatment and the biopsy technique are well tolerated by the horses. This drug could be helpful in altering bone remodeling and

healing, but further studies need to be completed.

Funding


Year Completed

In progress.

Influence of tiludronate on bone density and bone formation in young horses



Comparative Biomedical Sciences; Heather Richbourg, Department of Comparative Biomedical Sciences; School of Veterinary

Medicine, Louisiana State University

Introduction

Orthopedic disease is a major performance limiting problem for equine athletes. Analgesics, anti-inflammatories, regenerative

therapies and supplements are all routinely used to try and help maintain, correct or prevent injury from occurring. New therapies are

being investigated, and tiludronate is one that has demonstrated some beneficial effects on horses with navicular disease and back

pain.

Tiludronate is a bisphosphonate drug that was investigated as a treatment for diseases such as Paget’s disease or osteoporosis in

humans but has now been replaced by more potent alternatives. Tiludronate has been shown to inhibit bone resorption by causing

osteoclast apoptosis and disrupting the formation and secretion of proinflammatory mediators.

Histopathology and histomorphometry have been performed on multiple species treated with tiludronate at varying doses and

durations. Tiludronate is able to ameliorate the decreases in bone mineral density following various surgical or pharmacologic

treatments in other species. No histopathologic or histomorphometric study has been performed in horses and since this drug is

being more widely used in a clinical setting, including young horses to treat navicular disease or bone pain, the effects on normal

bone remodeling in horses should be investigated.

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SURGERY

Experimental Design

Ten young horses (<5 years of age) will be used for this study. Five horses will be in the treatment group and will receive clodronate,

with the other 5 being treated with a placebo (saline). Unilateral biopsy of the tuber coxae will be performed on each horse. After

collection of the first biopsy, tiludronate (1 mg/kg) will be administered IV, diluted in 1L of 0.9% saline, over 90 minutes. The control

group will receive only saline. The horses will then be placed in a stall in the research barn overnight for monitoring, before being

turned out the following morning. Thirteen days prior to the second biopsy, oxytetracycline (25mg/kg IV) will be administered.

This dose of oxytetracycline will be repeated three days prior to the second biopsy being performed. Sixty days after tiludronate

administration, we will collect the second biopsy, from the contralateral tuber coxae. The biopsy procedure and the sample

processing techniques are described in more detail in the abstract “Assessment of tuber coxae bone biopsy in the standing horse”.

Results

There were no significant changes in bone structure parameters as evaluated by microCT. Comparing Day 0 biopsy to Day 60

biopsy, tiludronate treated horses had significantly increased trabecular bone thickness. There were no significant differences in

bone remodeling parameters after 60 days.

Take Home Message

This treatment and the biopsy technique was well tolerated by the horses. Tiludronate was not found to significantly alter the

bone that was investigated. This may indicate that the drug may help alleviate pain by some other mechanism of action other than

was investigated in this study, or the timeframe was not long enough to identify significant changes within the tissue. The region

of the pelvis that was biopsied is non weight bearing, which may also have influenced the results, although the drug is found to

concentrate in this region. This drug could be helpful in altering bone remodeling and healing, but further studies need to be

completed.

Funding


Year Completed

2014-2016.

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THERIOGENOLOGY

Preeclamptic Mouse Model: Investigation of the Embryo-Uterine Interactions that Will Improve Mare-Foal Outcomes


Jenny L. Sones1,2, Jeeyeon Cha3, Ashley K. Woods1, Amanda Bartos3, Christa Y. Heyward1, Heinrich E.

Lob1, Catherine E. Isroff1, Scott D. Butler1, Stephanie E. Shapiro1, Sudhansu K. Dey3, Robin L. Davisson1,4

1Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853; 2Veterinary

Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803; 3Division of Reproductive Sciences, Cincinnati Children’s Research Foundation, Cincinnati, OH 45229; 4Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10021

Introduction

Preeclampsia is a devastating disorder of pregnancy that manifests as late gestational maternal

hypertension but can be life-threatening to both mother and baby. It is believed that abnormal

placentation is responsible for the cascade of events leading to the maternal preeclamptic syndrome; however, the exact

mechanisms are unknown. Embryo implantation is critical to establishing a healthy pregnancy. Defective implantation may contribute

to adverse “ripple effects” leading to abnormal placentation, retarded fetal development and poor pregnancy outcomes, such as

preeclampsia, fetal growth restriction and pregnancy loss.

Objectives

The objectives of this study were to utilize the spontaneous mouse model of preeclampsia, BPH/5, to investigate the peri-

implantation period and test the hypothesis that aberrations early in pregnancy contribute to

poor fetal and placental development, as well as the maternal preeclamptic syndrome in this

model.

Methods

BPH/5 and control C57 implantation sites were collected from pregnant mice during the

peri-implantation period and subjected to molecular analyses, qRT-PCR, in situ hybridization,

Western blotting, ELISA, was used to identify dysregulated implantation signaling molecules.

Flow cytometry was utilized to characterize the immune cell population at the maternal-fetal

interface in these implantation sites. Fetal health status was determined by ultra-high frequency ultrasonography, and maternal

hypertension was assessed by radiotelemetry.

Results

• BPH/5 exhibit peri-implantation defects at the maternal-fetal interface:

o Upregulation of cyclooxygenase 2 (Cox2) and interleukin 15 (IL-15)

o Decreases in decidual natural killer (dNK) cells, which have an important role in establishing placental perfusion

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THERIOGENOLOGY

• Administration of a selective Cox2 inhibitor (celecoxib) during early pregnancy improved BPH/5 pregnancy outcomes:

o Restrained decidual Cox2 and IL-15 expression

o Restored dNK cell numbers

• Increased fetal growth and attenuated late gestational maternal hypertension

Conclusions

• Decidual overexpression of Cox2 and IL-15 may trigger adverse pregnancy outcomes

• Cox2 inhibition may be a targetable strategy to prevent fetal and maternal morbidity/mortality

Translational Aspects

Ongoing efforts in the Theriogenology section at LSU SVM includes taking a similar molecular approach to investigate the embryo-

uterine interactions in the mare and how adverse ovarian hormone signaling can have “ripple effects” on pregnancy outcomes in the

horse.

Published Manuscripts/Abstracts

Sones, J.L., Davisson, R.L. (2016) Preeclampsia, Of Mice and Men. Physiol Genomics 48 (8): 565-72. PMID:27260843

Sones, J.L., Cha, J., Woods, A.K., Bartos, A., Heyward, C.Y., Lob, H.E., Isroff, C.E., Butler, S.D., Shapiro, S.E., Dey, S.K., Davisson, R.L.

(2016) Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model. JCI Insight 1(3). PMID:

27159542.

JL Sones, CY Heyward, D Lessard, SD Butler, HE Lob, RL Davisson. Normalization of Uterine Interleukin (IL)-15 in the BPH/5

Preeclamptic Mouse Improves Decidual Natural Killer Cell Activation at the Maternal-Fetal Interface. (Hypertension. 2015; 66:A039)

JL Sones, SD Butler, SE Shapiro, J Cha, SK Dey, RL Davisson. Cox2 Inhibition in Early Pregnancy Improves Adverse Outcomes in the

BPH/5 Mouse Model of Preeclampsia. (FASEBJ. Vol. 29, No. 1 [Supplement 684.11]).

JL Sones, SD Butler, CE Isroff, J Cha, SK Dey, RL Davisson. Cox2 Inhibition During Decidualization Improves Fetal Growth Restriction

In The BPH/5 Mouse Model Of Preeclampsia. (Hypertension. 2014; 64:A094; Best of AHA [top 10%] accepted abstracts)

JL Sones, HE Lob, CE Isroff, J Song, E Williamson, RL Davisson. BPH/5 Pre-eclamptic Mice Have Increased Uterine Interleukin (IL)-15

and This Is Associated with Decidual Natural Killer (dNK) Cell Loss At The Maternal-Fetal Interface Early In Pregnancy. (Hypertension.

2014; 64:A028; Best of AHA [top 10%] accepted abstracts)

Sones, J.L., Lob, H.E., Isroff, C.E., Davisson, R.L. (2014) The Role of Decidual Natural Killer cells, Interleukin-15 and Interferon-γ in

Placental Development and Preeclampsia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 307:490-2. PMID:24920727

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THERIOGENOLOGY

Funding (Sones)

Louisiana Biomedical Council Research Program, The

role of maternal adipose tissue in the preeclamptic-like

BPH/5 mouse. $50,000.

NICHD National Centers for Translational Research

in Reproduction and Infertility, Cornell Center for

Reproductive Genomics (Seed grant), The role of

microRNAs in defective periimplantation signaling

observed in the spontaneous BPH/5 mouse model of

preeclampsia. $7,500.

American Heart Association, Postdoctoral Fellowship.

Role of asynchronous embryo-uterine interactions

during the peri-implantation period in a mouse model of

preeclampsia. $96,000.

94

DEVELOPMENT

How You Can Support the EHSP and Enhance the Health, Well-Being and Performance of Horses

There are many ways individuals, foundations and companies can help support the LSU School of Veterinary Medicine’s Equine

Health Studies Program. The EHSP is dedicated to the health, well-being and performance of horses through veterinary research,

education and service. In order to fulfill our mission of becoming one of the premier equine biomedical centers in the country, we

have initiated a plan to generate funds to enhance all aspects of our program.

Professorships and Chairs

Endowed chairs and professorships provide perpetual support for outstanding faculty members. Donors give at least $1.2 million

to establish a chair, and the state provides an $800,000 match, yielding a total endowment of $2 million. A professorship is

funded through a $240,000 gift from a donor that the state matches with $60,000, yielding a $300,000 endowment. Each chair

or professorship is named by the donor who funds it. A portion of the earnings generated by the endowment fund for a chair is

typically spent to supplement the chair holder’s salary, as well as provide additional income for such special purposes as purchasing

publications that complement the chair’s work, hiring graduate and post-doctoral students to assist in research projects and buying

research equipment that could not otherwise be made available. An endowed professorship provides resources to recognize a

professor for academic achievement and enables him or her to pursue research and/or innovative teaching methods.

Equine Biomedical Research

Private gifts can provide funds for leading-edge science specific to the horse. With the limited amount of state and federal funding

available for equine scientific investigations, funds from private, charitable gifts are critical to improve successful prevention and

treatment of illnesses and injuries that can be performance-limiting, career-ending and even life-threatening.

General EHSP Support Fund

Gifts can be made to the General EHSP Support Fund (a non-endowed account). These funds may be used to purchase equipment

for equine scientific investigations. Additionally, they are used for continuing education for the horse-owning public and private

equine veterinarians. These funds also are used to assist with other educational, promotional and fundraising activities.

Equine Farrier Unit (right)

Gifts can be made to the Pfeiffer-Burt Lameness and Farrier

Unit. These funds will be used to supplement current funding to

provide equipment for diagnosis and treatment of medical and

surgical conditions of the equine hoof.

Memorial Gifts and Naming Opportunities

Your gift may be used to honor or memorialize a beloved

horse, family member or friend. Naming opportunities exist for

endowed gifts like scholarships, professorships and chairs. Newly

constructed facilities and novel projects offer a wide variety of

naming opportunities.

95

DEVELOPMENT

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DEVELOPMENT

Again, any gift will be special to the LSU School of Veterinary Medicine’s Equine Health Studies Program and will make a dramatic

and immediate impact on our teaching, service and scientific investigation programs. We thank you for your generosity and support.

To learn more about how your gift will assist the EHSP with its mission, please contact Clayton Forbes, Director of Development, at

225-578-9826 or [email protected].

I want to support the LSU SVM EHSP!

Please use my gift to continue the excellence in community service, education and research through the EHSP.

___ $500 ___ $250 ___ $100 ___ $________ Other

Your company may provide corporate matching funds. Please contact your employer’s human resources office for more information.

Name __________________________________________________________________ LSU SVM Graduation Year_______________

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Please make your check payable to: LSU FoundationMail to: Louisiana State University School of Veterinary Medicine Development Baton Rouge, LA 70803

Please use this form to make your gift, or call 225-578-9826 to make your gift by phone!

For information on ways to give:

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[email protected]

Director of Development

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EQUINE HEALTH STUDIES PROGRAM - lsu.edu for lameness, gastrointestinal disease, endocrine disease and respiratory disease, ... equine health and welfare. Sincerely, Joel Baines, VMD,