Epstein-Barr Virusand Human Cancer

K. Takada

I Molecular Mechanisms of Maintenanceand Disruption of Virus Latenc y

B . SUGDEN and E .R . LEIGH TEBV's Plasmid Replicon: An Enigma in cis and trans . . .

3

K. HIRAI ' and M . SII I RAKATA

Replication Licensing of the EBV oriP Minichromosome

1 3

S. FUJIWARAEpstein-Barr Virus Nuclear Protein 2-Induced Activatio n

of the EBV-Replicative Cycle in Akata Cells :Analysis by Tetracycline-Regulated Expression 3 5

L.M . HU'IT-FLETCHER and C.M . LAK E

Two Epstein-Barr Virus Glycoprotein Complexes 5 1

T. TSURUM IEBV Replication Enzymes 6 5

II EBV-Associated Malignancies

M . FUKAYAMA, J .-M . CHONG, and H . UOZAKIPathology and Molecular Pathology

of Epstein-Barr Virus-Associated Gastric Carcinoma . . . .

9 1

K. AOZASA, H . KANNO, H . MIwA, and Y . TOMITA

EBV and Malignant Lymphoma with Specia lEmphasis on Pyothorax-Associated Lymphoma 10 3

H. KATANO, T . SATA, and S . MOR I

AIDS Lymphoma : Its Virological Aspects 12 1

III Molecular Mechanisms of Oncogenesis

K. TAKAD A

Role of Epstein-Barr Viru s

in Burkitt's Lymphoma 141

I .K . RUF, P.W . RHYNE, H . YANG, C .M. BORZA ,

L.M. HUTT-FLETCHER, J .L . CLEVELAND, and J .T . SAMPLEEBV Regulates c-MYC, Apoptosis ,

and Tumorigenicity in Burkitt's Lymphoma 15 3

S. 1MAI, J . NISHIKAWA, M . KURODA, and K . TAKAD AEpstein-Barr Virus Infectio nof Human Epithelial Cells 16 1

T. SAIRENJI, M . TAJIMA, M . KANAMORI, N . TAKASAKA ,

X. GAO, M . MURAKAMI, K . OKINAGA, Y . SATOH ,Y. HOSHIKAWA, H . ITO, Y . MIYAZAWA, and T . KURAT A

Characterization of EBV-Infected Epithelial Cell Line sfrom Gastric Cancer-Bearing Tissues 18 5

IV Animal Model and New Therapeutic Approachto MalignancyF. WANG

A New Animal Model for Epstein-BarrVirus Pathogenesis 20 1

C .M. ROONEY, L.K. AGUILAR, M .H. HuLS ,

M .K . BRENNER, and H.E. HESLOPAdoptive Immunotherapy of EBV-Associated

Malignancies with EBV-Specific CytotoxicT-Cell Lines 22 1

Subject Index 231