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Epidemiology of Wolff- Parkinson-
White Syndrome in Singapore
---- A Preliminary result
Hossain SM, Bai Rong, Ching Chi
Keong, Jack Tan, Kuik Hwee Bing,
Ruth Kam, Teo Wee Siong
Objective
To find out the age, sex and racial
distributions of WPW syndrome
among the multi-ethnic
Singapore population.
Clinical significance of WPW
syndrome study
Associated with high frequency of
arrhythmias.
It shows bizarre and misleading
electrocardiographic pattern.
Can be cured by catheter ablation.
12 lead ECG showing different WPW
pathway
Manifest WPW
Methods
A retrospective study done in all WPW syndrome
patients admitted in NHC for catheter ablation from
Oct ’1991 to Dec’03.
Statistical analysis by chi-square and cross
tabulation methods.
Accessory pathway is determined by
• History and physical examination
• Analysis of surface 12 lead ECG
• Intracardiac mapping by EPS
Picture of normal conductive
system and wpw PATHWAY
Cinefilms to show intracardiac
catheters
Result
Male
N=462
Female
N=289
Total
N=751
M:F
1.6:1
Age 37±14 41±15 38±15 <0.01
Race
1) Chinese
2) Malay
3) Indian
4) Others
403
37
9
13
256
22
7
4
659
59
16
17
Single
pathway
432 273 705 (94%)
Multiple
pathway
30 16 46 (6%)
Bar chart showing the age
distributions in Single AP
AGE_GRP
70-7960-6950-5940-4930-3920-2910-19
Pe
rce
nt
30
28
26
24
22
20
18
16
14
12
10
8
6
4
20
Pie chart showing the percentage of the
each site in Single Accessory Pathway
3.5%
12.3%
3.0%
12.9%
68.2%
Others
Posteroseptal
Anteroseptal
Right free wall
Left free wall
Result - Racial distribution in
single pathway
Chinese Malay Indian Others p-value
Single pathway
1) LFW
2) RFW
3) Anteroseptal
4) Posteroseptal
5) Others
422
79
21
73
21
40
4
0
10
3
11
3
0
2
0
8
5
0
2
1
>0.05
X2 5.28 -5.64 -9.92 1.59
P-value <0.05 <0.05 <0.001 >0.05
Gender distribution in single
pathway
Male Female P-value
LFW 297 184
RFW 47 44
Anteroseptal 15 6
Posteroseptal 64 23
Others 9 16
<0.05
Conclusion
Male suffers more from WPW syndrome .
Highest incidence observed in 3rd and 4th
decade.
In Singapore LFW also topped the list
among the WPW syndrome pathways.
Thank you!