Eom Mcq Pathobio by Nuramalina Yahaya

7/28/2019 Eom Mcq Pathobio by Nuramalina Yahaya

1/11

Pathobio EOM

PATHOLOGY

1. The most common cause of cerebral hemorrhage inadults is :

A. traumaticB. hypertensionC. Ruptured bony aneurysmD. Arterio venous malformation

2. Sequalae of elevated intracranial pressure include allthe following EXCEPT :

A. Transtentorial herniationB. tonsillar herniationC. Erosion of skull bonesD. Hydrocephalus

3. The most common primary brain tumor isA. GliomaB. menengiomasC. SchwannomasD. Neurofibromas

4. The typr of amyloid depositin cases of osteomyelitis isA. ALB. AAC. all aboveD. None above


2/11

5. Osteoid osteoma has the following features EXCEPTA. Is a benign tumorB. the vertebrae are the most common bone involved

C. Presents with severe pain that specially relieved byaspirinD. Radiologically appear as translucent nidus surroundedby dense bone

6. Primary osteoporosis has the following featuresEXCEPT

A. More common in males

B. affected mainly vertebra bodies, femoral neck andmetacarpal boneC. Shows thin bony trabeculae and a wide marrow cavityD. May present with back pain and fracture

7. In osteomyelitis, sequestrum isA. A reactive envelope of subperiosteal bone

B. a fragment of necrotic boneC. A residual abscessD. Dense sclerotic bone

8. The following features of Hodgkin' lymphoma includethe following EXCEPT

A. Background of inflammatory cellsB. Reed stenberg cellsC. Background of malignant lymphoid cellsD. Often localized to axial group of lymph nodes

9. All is true about Burkitt's lymphoma EXCEPTA. Is a diffuse non hodgkin lymphoma


3/11

B. Is related EBVC. Is a T cell lymphomaD. Commonly affects African children

10. A 12-year-old girl present with a fever of 38 and aswollen lymph nodes of 6 days duration. The blood countis normal. Biopsy of swollen lymph node showsparacortical lymphoid hyperplasia. This pathologic findingis best interprreted as

A. Proliferation of B cellsB. proliferation of dendritic cells

C. Proliferation of T cell *D. Proliferation of plasma cell

PARASITOLOGY

11. Cutaneous larva migrans is caused by migratinglarvae of

A. Toxocara canisB.onchocercus volvulusC. W. bancroftiD. Ancylostoma braziliense

12. Which of the following parasitic stages are intracellularin man

A. Trypomastigote of T.cruziB. Microfilaria of loa loaC. Schizonts of P.falciparumD. Promastigote of Leismania

13. In malaria, jaundice caused by


4/11

A. Obstruction of bile ductB. haemolysis of RBC *C. Liver congestion

D. Anemia

14. The following stage can exist in the life cycle ofLeishmania

A. Promastigote *B. epimastigoteC. TrypomastigoteD. Metacyclic trypomastigote

15. Black water fever is a complication of infection withA. P. falciparumB. P. malariaeC. P. vivaxD. P. ovale

16. Infection with W.bancrofti occurs byA. Microfilaria in the proboscis CulexB. blood transfusionC. 3rd stage larva in proboscis CulexD. 3rd stage larva in the saliva of Culex

17. The intermediate host of Toxoplasma gondiiA. Females Anopheles mosquitoB. manC. Tsetse flyd. Phlebotamous papatasii

18. The diagnostic stage of Naegleria fowleri is


5/11

A. Amoeboid trophozoite formB. flagellated trophozoite formC. Cystic form

D. Cyst and trophozoite

19. It is recommended to give primaquine to patientsinfected with P. falciparum to kill

A. SprozoiteB. gametocyteC. Hypnozoite *d. Trophozoite

20. Blood transfusion can transmit the following parasitesEXCEPT

A. T. CruziB. P.ovaleC. Indian type of leishmania donovaniD. W.bancrofti

21. Cysticercosis is caused by infection withA. Taenia saginata eggsB. taenia solium eggsC. CysticercouscellulosaeD. Cysticercous bovis

22. All of the following statements concerning osseoushydatid cyst are true EXCEPT

A. It has an irregular branching shapeB. it is not surrounded by fibrous tissueC. The germinal layer is poorly developedD. Develops slowly 2-10 years


6/11

PHYSIOLOGY

23. shivering with fever is due toA. Increased secretion of adrenalineB. voluntary skeletal muscle contractionC. Release pf PG that changes thermostat set pointD. Incresed secretion of thyroxin

24. Manifestation of cold exposure isA. Excessive sweating

B. shiveringc. Vasodilatation of skin vesselsD. Loss appetite and inertia

PHARMACOLOGY

25. The following statement about Fluoxetine is corrct

A. It is useful in obsessive compulsive disorder *B. it is a major stimulant pf P 450 systemC. It has more anticholinergic effects than amitriptylineD. It does not cause sexual dysfunction

26. The following drug can oroduce serotonin syndrom ifgiven concurrently with MAOIs

A. BupropionB. fluoxetineC. TranylcypromineD. Chlorpromazine


7/11

27. An antiepileptic drug relatively safe to begin duringpregnancy is

A. Phenytion

B. na valproateC. LamotrigineD. None above

28. A 13-year-old male suffers to tonic clonic seizureswithin 1 week. He is diagnosed with epilepsy andphenytoin therapy is started. To achieve proper drugconcentration in plasma, the patient is first given a loading

dose, followed by maintenance doses. What us therational behind such regimen.

A. If drug is administered at a maintenance dose rate,steady state concentration will be reached after two halflivesB. a loading dose is administered to achieve the desiredplasma concentration rapidly

C. Loading dose of the drug does not depend on thevolume of distribution, whereas the maintenance dosedoesD. Maintenance dose rate not depend on clearance of thedrug, while the loading dose does

29. Which of the following correctly describes the formulaof an IV loading dose ( F= 1)

A. Loading dose = (desired plasma concentration of drug)x (clearance)B. loading dose = (0.693) x (volume of distribution) x(clearance)


8/11

C. Loading dise = (amount of drug administered) / (initialplasma concentration)D. Loading dose = (desired plasma concentration of drug)

x (volume of distribution)

30. A 50-year old female patient suffers from rheumatoidarthritis. She started to complain of pain and swelling ofthe small joints of hands and feet. You prescribeazathioprine to controlling the disease activity . Theappropriate investigation to monitor adverse effects of thedrug is

A. Complete blood pictureB. fasting blood glucose levelC. serum cholestrol levelD. Serum calcium level

31. An antiepiletic drug contraindicated to be given tocases of absence epilepsy is

A. EthosuximideB. carbamazepine*C. Na valproateD. Clonazepam

32. Pancreatitis is an idiosyncratic side effect of thefolloeing antiepileptic drug

A. LamotrigineB. ClonazepamC. Na valproateD. Phenytoin

MICROBIOLOGY


9/11

33. Human transmission of Brucellosis occurs via thefollowing routes EXCEPT

A. Contact with vaginal discharge of urine animalsB. drinking of unpasteurized milkC. Direct contact with animal tissuesD. Inhalation of infected droplets

34. Infection with dermatophytes is most often associatedwith

A. IV drug abuse

B. inhalation of organism from contaminated bird fecesC. Adherence of teh organism to moist skinD. Fecal oral transmission

35. Which one of the following can be detected at theearliest stage is the serum of the person infected with HIV

A. P24

B. P31C. P1D. P160

36. The incubation period of Rabies virus seems to berelated to

A. Infecting dose of the virusB. transmitting vectorC. Type of woundD. Distance between wound and the spinal cord

37. Multinucleated giant cells is associated with infectionby


10/11

A. EBVB. Herpes simpex virusC. Retrovirus

D. Rabies virus

38. All of the following are routes of transmission ofcytomegalovirus EXCEPT

A. Intrauterine lifeB. droplet infectionC. Blood transfusionD. Organ transplantation

39. All are true about Rabies virus EXCEPTA. Bullet shape neurotropic virusB. multiplies at the site of inoculationC. The genome is SS RNAD. The administered vaccine elicit cell mediated immuneresponse

40. The commonest site if infection for anthrax bacilli isA. IntestineB. skin*C. LiverD. Blood vessels

41. The toxins that cause tetanus isA. ExotoxinsB. endotoxinsC. Exotoxins with minor endotoxic propertiesD. Enterotoxins


11/11

42. Which one of the following viruses can cross theplacenta and cause disease to the fetus

A. Rubella virus

B. herpes simplex type IC. Arbo virusD. EBV

BIOCHEMISTRY

43. All of the following are true about metal ionsequestration EXCEPT

A. it is prevented by ferritinB. it is protective against oxidative stressC. It interferes with initiation of the chain reactionpropagation in lipid moleculesD. Needs metal binding proteins

44. The reaction catalysed by NADPH oxidase will

generateA. HOClB. H2O2C. NO'D. Superoxide anion

Documents

Eom Mcq Pathobio by Nuramalina Yahaya